CURRICULUM VITAE
Ehab A. Abourashed PhD
Ehab A. Abourashed PhD
Professor
Department of School of Pharmacy Administration
Division of Administration
Department of School of Pharmacy Administration
Division of Administration
OFFICE ADDRESS: |
Health Research Center |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
EDUCATION: |
1981 - 1986 Bachelor of Pharmaceutical Sciences, Cairo University, Egypt |
1991 - 1993 MS, Organic Chemistry, University of Tennessee, Knoxville, TN |
1993 - 1998 PhD, Pharmacognosy, University of Mississippi, Oxford, MS |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
1998 - 2001 Postdoctoral Research Associate, School of Pharmacy, National Center for Natural Products Research, University of Mississippi, Oxford, MS 38677 |
FACULTY APPOINTMENTS: |
1998 - 2000 Instructor, Parmacognosy, University of Mississippi, Oxford, MS 38677 |
2002 - 2006 Assistant-Associate Professor, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia |
2009 - 2012 Assistant Professor, College of Pharmacy, Chicago State University, Chicago, IL 60628 |
2012 - 2016 Associate Professor, College of Pharmacy, Chicago State University, Chicago, IL 60628 |
2017 - 2020 Associate Professor, School of Pharmacy, Medical College of Wisconsin, Milwaukee, WI |
2020 - Present Professor, School of Pharmacy, Medical College of Wisconsin, Milwaukee, WI |
ADMINISTRATIVE APPOINTMENTS: |
2006 - 2009 Director of Quality Assurance, ElSohly Laboratories, Inc., Oxford, MS 38655 |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
10/01/2011 - 12/31/2012 Interim Chair, Pharmaceutical Sciences, Chicago State University, Chicago, IL 60628 |
07/01/2020 - Present Assistant Dean for Curricular Affairs, School of Pharmacy, Medical College of Wisconsin, Milwaukee, WI 53226 |
RESEARCH ADMINISTRATIVE APPOINTMENTS: |
2001 - 2002 Senior Scientist, Consumer Healthcare R&D, GlaxoSmithKline, Parsippany, NJ |
SPECIALTY BOARDS AND CERTIFICATION: |
Certificates | Issued By | Issue Date | Expiration |
United States Foreign Pharmacy Graduate Equivalency Examination (FPGE) | National Association of Boards of Pharmacy | 1997 | None |
AWARDS AND HONORS: |
1998 Best Poster, The Scientific Research Honor Society |
1998 Travel Grant, Lloyd Library and Museum |
2011 - 2014 Student’s Teacher of the Year, Chicago State University College of Pharmacy |
2014 Best Abstract, Scripps Institute 11th Annual Natural Supplements Conference |
2014 Faculty Excellence Award in Rsearch & Creative Activity, Chicago State University |
2016 Student’s Teacher of the Year, Chicago State University College of Pharmacy |
03/2017 - Present Runner-up for Best Overall Research, Greenville Health System/University of South Carolina |
05/03/2017 Best Capstone Poster for a Graduating Student, Chicago State University |
2020 - Present Student Instructor of the Year, Medical College of Wisconsin School of Pharmacy |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
1995 - Present American Society of Pharmacognosy (ASP) (Member) |
1996 - Present The Scientific Honor Society Phi Kappa Phi) (Member) |
1997 - Present The Pharmacy Honor Society Rho Chi (Member) |
2007 - Present American Chemical Society (ACS) (Member) |
2009 - Present American Association of Colleges of Pharmacy (AACP) (Member) |
2012 - Present The Pharmacy Leadership Society Phi Lambda Sigma (Member) |
2015 - Present Phytochemical Society of North America (PSNA) (Member) |
2016 - Present The Scientific Research Honor Society (Member) |
2018 - Present American Pharmacist Association (APhA) (Member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
2018 - Present Antioxidants |
Editorial Board |
2013 - 2017 Antioxidants |
Journal Review |
2001 - Present Journal of Natural Products |
2002 - 2006 Saudi Pharmaceutical Journal |
2004 - Present Journal of Pharmaceutical and Biomedical Analysis |
2009 - Present Journal of Chromatographic Science |
2010 - Present Phytochemistry |
2010 - Present Fitoterapia |
2011 - Present Journal of Agricultural and Food Chemistry |
2011 - Present Journal of Advanced Research |
2013 - Present Antioxidants |
2018 - Present Innovations in Pharmacy |
2018 - Present American Journal of Pharmacy Education |
Ad-Hoc Reviewer |
2002 - Present Planta Medica |
2011 Ph.D. thesis reviewer for Andhra University, College of Pharmaceutical Sciences, India. Thesis title is ‘Polypills of Cardiovascular Drugs-Estimation and Validation by New HPLC Methods’ |
2012 - Present Grant Reviewer, Sultan Qabous University, Oman |
2013 - Present American Association of Colleges of Pharmacy (AACP) New Investigator Grant Reviewer |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
10/19/2012 - 10/20/2012 Member, Organizing Committee - 2012 David Slatkin Symposium, Chicago State University College of Pharmacy |
08/2017 - Present Member, Planning Council, Midwest Teacher Scholar Retreat |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2005 Member, Scientific Committee, 9th International Pharmaceutical Conference and Exposition, King Saud University |
2011 Ph.D. thesis reviewer, Andhra University, India. Thesis title: ‘Polypills of Cardiovascular Drugs-Estimation and Validation by New HPLC Methods’, College of Pharmaceutical Sciences |
2012 - Present Grant Reviewer, Sultan Qabous University, Oman |
2014 Member, Organizing Committee, 2nd International Conference and Exhibition on Pharmacognosy, Phytochemistry & Natural Products, Omics Group Inc. |
2015 Ph.D. thesis reviewer, Ancient apple (Malus X domestica Borkh) Varieties from Tuscany: Study of Antioxidant Compounds in Relation to Human Health’., Institute of Life Sciences, Sant'Anna University, Italy |
INTERNATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
12/17/2005 Member, Scientific Committee - 9th International Pharmaceutical Conference and Exposition, King Saud University |
08/25/2014 - 08/27/2014 Member, Organizing Committee - 2nd International Conference and Exhibition on Pharmacognosy, Phytochemistry & Natural Products, Omics Group Inc. |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Local |
Herbal Medicines: Potentials, Problems, Procedures, University of Mississippi, Department of Pharmacognosy, 04/2000 |
Analytical and Biological Applications for the Assessment of Medicinal Plants and Herbal Products, Student Committees Annual Presentation, King Saud University, College of Pharmacy, 01/2003 |
The Many Faces of Qtrap MS: Applications of hybrid LC/MS/MS in Drug Forensics, Metabolism and Discovery, University of Mississippi, Department of Pharmacognosy, 09/2008 |
The Curious Case of Some CNS-Acting Herbs, Chicago State University, Department of Biological Sciences, 02/2010 |
Phytochemical Analysis from Fingerprinting to Marker Identification, Chicago Botanic Garden, 10/2011 |
Total Quality Systems: Overview of FDA Guidelines for QA and QC, Chicago State University College of Pharmacy, 11/2011 |
Ehab A. Abourashed, Toxic Plants of the Midwest, Toxicology Rounds Monthly Meetings, Medical College of Wisconsin, Milwaukee, WI, 02/2017 |
Natural is not always Safe: Dietary Supplement-Related Cardiovascular Toxicities, Toxicology Rounds Monthly Meeting, Medical College of Wisconsin, Milwaukee, WI, 10/2018 |
Regional |
In Search for New Bioactive Leads: The Role of Microbial Transformation, West Virginia University, Department of Basic Pharmaceutical Sciences, 11/2008 |
Biocatalytic Bugs: Microbial Transformation in Drug Discovery & Development, Associated Colleges of the Chicago Area (ACCA) Lecture Series, Dominican University, Chicago, IL, 11/2012 |
Ehab A. Abourashed, Abir T. El-Alfy, Just a Fancy Spice or More? Therapeutically Significant CNS Targets of Nutmeg Secondary Metabolites, David J. Slatkin Memorial Symposium, Chicago State University, IL, 11/2016 |
Abourashed EA, Health Benefits of Hemp, Marijuana, CBD and THC - A Reality Check, Hemp Help: Growing Your CannaBusiness in Wisconsin, University of Wisconsin-Parkside, Kenosha, WI, 03/2019 |
Medical Potential of Maclura pomifera as a Source of Bioactive Secondary Metabolites, National Center for Agricultural Utilization Research - Invited Presentation, USDA-ARS, Peoria, IL, 06/2019 |
National |
The Quest for Ideal Nutraceuticals, 14th Annual Meeting of the Nonprescription Medicines Academy, Cincinnati, OH, 10/2011 |
Common Herbs as a Renewable Source for Discovering Small Molecules with Potential Against Brain and Psychological Disorders, 97th Annual Meeting of the American Association for the Advancement of Science (AAAS), University of San Diego, CA, 06/2016 |
Ehab A. Abourashed, Abir T. el-Alfy, Just a Fancy Spice or More? Therapeutically Significant CNS Targets of Nutmeg Secondary Metabolites, 2016 David Slatkin Symposium, Chicago State University, Chicago, IL, 11/18/2016 |
Ehab A. Abourashed, Biocatalytic Conversions of Natural Products – Utility in Drug Discovery and Development, 98th Annual Meeting of the Pacific Division of AAAS, Hawai`i Preparatory Academy, Waimea, HI, 06/2017 |
Utility of LC-MS/MS in Forensic Analysis and Metabolite Identification, 2nd Annual Mass Spectrometry Research Symposium, Medical College of Wisconsin, Milwaukee, WI, 06/2018 |
International |
Implications of Secondary Metabolite Content Variation on Potential Benefits of Medicinal Plants, 3rd International Conference of Pharmaceutical Sciences, Future University, Cairo, Egypt, 02/2015 |
The non-volatile constituents of nutmeg—a key to solving an old riddle?, 54th meeting of the Phytochemical Society of North America (PSNA), University of Illinois, Urbana-Champaign, IL, 08/2015 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
Regional |
SI Khan, EA Abourashed, IA Khan, and LA Walker, Transport of Harman Alkaloids from Dietary Supplements Across Caco-2 Cell Monolayers, 21st Annual Meeting of Southeastern Pharmacology Society, Jackson, MS, 2000 |
K Ezell, EA Abourashed, W Gul, MA ElSohly, AT El-Alfy, Real-Time Drug Abuse by Measurement of Influent Wastewater in Sewage Treatment Plants, MidSouth SETAC meeting, Memphis, TN, 05/2010 |
SA Awan, A Abraha, EA Abourashed, In Search for Natural Tau Fibrillization Inhibitors: Preliminary Investigation of Horse Apple Fruit, 46th Midwest / 39th Great Lakes Joint Regional Meeting of the American Chemical Society, St. Louis, MO, 10/2011 |
EA Abourashed, MM Hefnawy, HI El-Subbagh, Application of Three Chromatographic Techniques in the Bioanalysis of a New Thiazolodiazepin Ultra-Short-Acting Hypnotic, 46th Midwest / 39th Great Lakes Joint Regional Meeting of the American Chemical Society, St Louis, MO, 10/2011 |
A Wardlow, N Sidelnikova, EA Abourashed, Isolation and Yield Maximization of the Major Constituents of Horse Apple Fruit, 2012 David Slatkin Symposium, Alsip, IL, 10/2012 |
SA Awan, A Abraha, EA Abourashed, In Search for Natural Tau Fibrillization Inhibitors: Preliminary Investigation of Horse Apple Fruit, Alzheimer’s Disease Conference: Translating Research into Care. Greater Illinois Chapter of the Alzheimer's Association, Chicago State University, Chicago, IL, 06/2014 |
AT El-Alfy and EA Abourashed, Engagement of PharmD Students in a Natural Products Drug Discovery Research Program: Successes and Challenges, Midwest Teacher Scholar Retreat, Manchester University, Fort Wayne, IN, 11/2015 |
EA Abourashed, Design, Delivery and Outcomes of an Elective Course on Substance Abuse and Addiction, 2nd Midwest Teacher Scholar Retreat, Manchester University, Fort Wayne, IN, 11/2016 |
EA Abourashed, Using a Final Year Capstone Project as a Platform to Introduce Student Pharmacists to the Concept of Natural Products Drug Discovery, 3rd Midwest Teacher Scholar Retreat, Manchester University College of Pharmacy, Fort Wayne, IN, 11/2017 |
EA Abourashed, Organic Chemistry Refresher as an Optional Activity in a Pharmacy Biochemistry Course, 4th Midwest Teacher Scholar Retreat, Sullivan University, College of Pharmacy, Louisville, KY, 11/2018 |
National |
NJ Toyang, EA Abourashed, J Choinski, IA Khan, Isolation and Biological Evaluation of Two New Flavone Glycosides From Paullinia Pinnata, Interim Meeting of the American Society of Pharmacognosy, Tunica, MS, 1999 |
EA Abourashed, RB Manyam, IA Khan, Comparative Analysis of Feverfew Products, Interim Meeting of the American Society of Pharmacognosy, Tunica, MS, 1999 |
CE Müller, B Schumacher, A Brattström, EA Abourashed, U Koetter, Adenosine Receptor Interactions: A New Probe for Investigating the Mechanism of Action of a Fixed Valerian-Hops Extract Combination (Ze 91019, Alluna), American Society of Pharmacognosy & Council for Responsible Nutrition Interim Meeting, Asilomar, CA, 2001 |
T McDowell, N Sidelnikova, EA Abourashed, Adopting a Traditional Phytochemical Approach to Solve the Riddle of Nutmeg, Spring Symposium & Student Research Conference in STEM, Chicago, IL, 02/2012 |
D Gemeda, W Fanouth-Ngyessen, EA Abourashed, Enhancing the Lipophilicity of Silybin by Esterification, Spring Symposium & Student Research Conference in STEM, Alsip, IL, 02/2013 |
International |
EA Abourashed, FS ElFeraly, IA Khan, R Bauer, CD Hufford, Metabolism Studies of Maesanin, 39th Annual Meeting of the American Society of Pharmacognosy, Orlando, FL, 1998 |
EA Abourashed, J Vanderplank, IA Khan, High Speed Extraction and HPLC Fingerprinting of Medicinal Plants – Application to Passiflora Alkaloids, International Conference on Ethnomedicine and Drug Discovery, Silver Springs, MD, 1999 |
EA Abourashed, IA Khan, NH Fischer, HPLC Fingerprinting of Sesquiterpene Lactones of Magnolia Grandiflora, 41st Annual Meeting of the American Society of Pharmacognosy, Seattle, WA, 07/2000 |
SI Khan, EA Abourashed, IA Khan, LA Walker, Transport of Marker Compounds from Dietary Supplements Across Caco-2 Cell Monolayers – A Model Of Human Intestinal Absorption, 41st Annual Meeting of the American Society of Pharmacognosy, Seattle, WA, 2000 |
EA Abourashed, I Muhammad, M Resch, R Bauer, FS El-Feraly, CD Hufford, In Vitro Evaluation of Maesanin and Analogs as 5-Lipoxygenase and Cyclooxygenase-1 Inhibitors, 41st Annual Meeting of the American Society of Pharmacognosy, Seattle, WA, 2000 |
EA Abourashed, RB Manyam and IA Khan, The Use of Microbial Models to Probe Mammalian Metabolism of Kava Constituents, 41st Annual Meeting of the American Society of Pharmacognosy, Seattle, WA, 2000 |
EA Abourashed, U Koetter, A Brattström, In vitro binding experiments of the Fixed Valerian-Hops combination extract Ze91019 to Melatonin and Serotonin receptors, Joint meeting of the American Society of Pharmacognosy & the Phytochemical Society of Europe, Phoenix, AZ, 07/2004 |
EA Abourashed and JS Mossa, Determination of Caffeine in Stimulant Herbal Products and Power Drinks by High Performance Thin Layer Chromatography, Joint meeting of the American Society of Pharmacognosy & the Phytochemical Society of Europe, Phoenix, AZ, 07/2004 |
EA Abourashed and A Brattström, Gastrointestinal Absorption of the Two Component Extracts of a Combined Valerian/Hops Preparation (Ze91019) in Humans – A Preliminary Study, Joint meeting of the American Society of Pharmacognosy & the Phytochemical Society of Europe, Phoenix, AZ, 07/2004 |
AM Galal, EA Abourashed, JS Mossa, Combination effect enhancement of the antimicrobial activity of isoniazide, streptomycin, 6-paradol, 6-shogaol and isoeugenol, 46th Annual meeting of the American Society of Pharmacognosy, Corvallis, OR, 07/2005 |
EA Abourashed, The Utilization of Thin Layer Densitometry as a Novel Platform for the Evaluation of the Free Radical Scavenging Capacity of Natural and Semisynthetic Antioxidants, 9th International Pharmaceutical Conference and Exposition, King Saud University, Riyadh, Saudi Arabia, 12/2005 |
EA Abourashed, MS Abdel-Kader, AM Habib, Application of HPTLC for the Determination of Active Ingredients in Herbal and Pharmaceutical Products, 9th International Pharmaceutical Conference and Exposition, King Saud University, Riyadh, Saudi Arabia, 12/2005 |
EA Abourashed, T Al-Howiriny, JR Mikell, IA Khan, Microbial transformation of Ferutinin and Silybin by Cunninghamella elegans, 9th International Pharmaceutical Conference and Exposition, King Saud University, Riyadh, Saudi Arabia, 12/2005 |
SM Al-Massarany, FA Abbas, S Khan, B Demirci, KH Başer, AJ Al-Rehaily, TA Al-Howiriny, JS Mossa, EA Abourashed, Triterpene, Phenolic and Volatile Constituents of Commiphora opobalsamum L. growing in Saudi Arabia, 9th International Pharmaceutical Conference and Exposition, King Saud University, Riyadh, Saudi Arabia, 12/2005 |
NM Al-Musayeib, AM Galal, K El-Deeb, ME Amer, JS Moussa, SI Khan, EA Abourashed, Phytochemical Investigation and Preliminary Biological Activities of Arnebia hispidissima and Echium rauwolfii growing in Sadui Arabia, 48th Annual meeting of the American Society of Pharmacognosy, Portland, ME, 07/2007 |
EA Abourashed, AT El-Alfy, MA ElSohly, Fingerprinting of Nutmeg and Quantitation of its Major Constituents by HPLC-DAD, 50th Annual meeting of the American Society of Pharmacognosy, Honolulu, HI, 07/2009 |
S Akati, EA Abourashed, and AT El-Alfy, Inhibition of Endocannabinoid Degradation Enzymes by Nutmeg Extracts, American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, Chicago, IL, 10/2012 |
EA Abourashed, JR Mikell, IA Khan, Utilization of Microbial Transformation to Enhance the Free-Radical Scavenging Activity of Silybin, American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, Chicago, IL, 10/2012 |
EA Abourashed, V Thakkar, J Zawada, Chemical Profiling of Botanical Supplements – Outcomes of a Capstone Project on Borututu Bark, 114th Annual Meeting of the American Association of Colleges of Pharmacy (AACP), Chicago, IL, 07/2013 |
AT El-Alfy, S Joseph, A Brambhatt, EA Abourashed, Indirect Modulation of the Endocannabinoid System by Nutmeg Extracts: Potential Therapeutic Applications, 114th Annual Meeting of the American Association of Colleges of Pharmacy (AACP), Chicago, IL, 07/2013 |
EA Abourashed, SI Khan, A Abraha, Phytochemical Analysis and Preliminary Pharmacological Evaluation of Horse Apple as a Sustainable Source for Biocative Isoflavones, 2nd International Conference and Exhibition on Pharmacognosy, Phytochemistry & Natural Products, Beijing, China, 08/2014 |
K Manlimos, N Patel, EA Abourashed and AT El-Alfy, Inhibition of endocannabinoid catabolizing enzymes: potential mechanism of anxiolytic action of chamomile and nutmeg, Annual Meeting of the American Association of Colleges of Pharmacy (AACP), Anaheim, CA, 07/2016 |
EA Abourashed, HW Fu, Chemical Marker Profiling of Borututu Bark - An Emerging Antioxidant Herbal Dietary Supplement, Pittcon Conference & Expo, Chicago, IL, 03/2017 |
AT El-Alfy, E Walcheske, J Spiess, K MacKinnon, M DeBisschop, EA Abourashed, N Lamberton, M Letizia, S Broadway, S Korek, D Beatty and G MacKinnon, Unlocking the Power of Reflections to Implement a Longitudinal Co-curriculum in an Accelerated Pharmacy Program, Annual Meeting of the American Association of Colleges of Pharmacy (AACP), Chicago, IL, 07/2019 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
02/2017 - 03/2017 Member, Search Committee - Clinical faculty, School of Pharmacy, Medical College of Wisconsin |
03/2017 - Present Member, Global Health Liaisons, Medical College of Wisconsin |
03/2017 - 04/2017 Chair, Search Committee - Program Manager for Assessment, School of Pharmacy, Medical College of Wisconsin |
04/2017 - Present Chair, Curriculum Committee, School of Pharmacy, Medical College of Wisconsin |
04/2017 - Present Member, Assessment Committee, School of Pharmacy, Medical College of Wisconsin |
09/2017 - Present Member, Faculty Council, Medical College of Wisconsin |
09/2017 - Present Member, Faculty Council, Medical College of Wisconsin |
10/2017 - Present Member, Forensic Medicine & Sciences Committee, Medical College of Wisconsin |
03/2018 - 2019 Member, Annual Academic Assessment Exam, School of Pharmacy, Medical College of Wisconsin |
06/2018 - Present Member, Midwest Toxicology Collaborative Steering Committee, Medical College of Wisconsin |
10/2018 - Present Chair, Search Committee, Medicinal chemistry faculty, School of Pharmacy, Medical College of Wisconsin |
03/2019 - Present Member, ex-Officio, Faculty Council Governance Committee, Medical College of Wisconsin |
08/2019 - Present Member, Pre-Matriculation Program Workgroup, School of Pharmacy, Medical College of Wisconsin |
EXTRAMURAL TEACHING: |
Graduate Student Education |
08/1998 - 06/2000 University of Mississippi, School of Pharmacy, Spectroscopic Identification of Natural Products I & II |
08/1998 - 06/2000 University of Mississippi, School of Pharmacy, Medicinal Chemistry Research Methodology |
08/2002 - 06/2006 King Saud University, College of Pharmacy, Selected Topics in Natural Products Chemistry |
08/2002 - 06/2006 King Saud University, College of Pharmacy, Spectroscopic Identification of Natural Products I & II |
08/2003 - 06/2006 King Saud University, College of Pharmacy, Computer Applications in Pharmacognosy Research |
Pharmacy Student Education |
08/1998 - 06/2000 University of Mississippi, School of Pharmacy, Natural Product Derived Pharmaceuticals |
08/2002 - 06/2006 King Saud University, College of Pharmacy, Pharmaceutical Biotechnology |
08/2002 - 06/2006 King Saud University, College of Pharmacy, Antimicrobial Agents |
08/2002 - 06/2006 King Saud University, College of Pharmacy, Phytochemistry |
08/2009 - 12/2010 Chicago State University, College of Pharmacy, Pharmaceutical Biochemistry I & II |
01/2010 - 12/2016 Chicago State University, College of Pharmacy, Drug Action, Structure, and Therapeutics (DAST) III-VII |
08/2010 - 12/2016 Chicago State University, College of Pharmacy, Substances of Abuse & Addiction |
01/2011 - 05/2016 Chicago State University, College of Pharmacy, Complementary and Alternative Medicine |
08/2011 - 12/2016 Chicago State University, College of Pharmacy, Natural Products Electives & Capstone Projects |
08/2017 - Present Medical College of Wisconsin School of Pharmacy, PHAR 510 - Biochemistry, Course Director/Instructor |
01/2018 - Present Medical College of Wisconsin School of Pharmacy, PHAR 562 - Infectious Diseases I, Course Director/Instructor |
2018 - Present Medical College of Wisconsin School of Pharmacy, PHAR 683 - Substance Abuse Elective |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Undergraduate Students |
Ashley Wardlow, Chicago State University College of Pharmacy, 2011 - 2012 Research Advisor, RISE program, Peer-reviewed publication, poster presentation at regional meeting |
Triejaye McDowell, Chicago State University College of Pharmacy, 2011 - 2012 Research Advisor, RISE program, Oral presentation and recognition at national meeting |
Graduate Students |
PhD Students Advised |
Nawal M. AlMussayeib, King Saud University, 2002 - 2006 Pharmacognostical Investigation of Arnebia |
MS Students Advised |
Shaza M. AlMassarany, King Saud University, 2003 - 2006 Pharmacognostical Study of Commiphora opobalsamum L. |
Ibtissam ElSultan, King Saud University College of Pharmacy, 2004 - 2006 A Phytochemical and Biological Study of Maytenus arbutifolia (Fam. Celastraceae), Thesis defended successfully. Degree bestowed. |
Pharmacy Students |
Saad Awan, Chicago State University College of Pharmacy, 01/2011 - 05/2011 Research Elective, Peer-reviewed publication |
Ketur Darji, Chicago State University College of Pharmacy, 06/2011 - 05/2012 Capstone project, Peer-reviewed publication |
Vaidehi Thakar, Chicago State University College of Pharmacy, 06/2012 - 05/2013 Capstone project, Poster presentation at national meeting |
Jadwiga Zawada, Chicago State University College of Pharmacy, 06/2012 - 05/2013 Capstone Project, Poster presentation at national meeting |
Chelsey Imel, Chicago State University College of Pharmacy, 2012 - 2013 Capstone project co-advisor, Oral presentation at national meeting |
Wenceslas Fanouth-Nguyesson, Chicago State University College of Pharmacy, 2012 - 2013 Capstone project, Poster presentation at national meeting |
Dereje Gemeda, Chicago State University College of Pharmacy, 2012 - 2013 Capstone project, Poster presentation at national meeting |
Alicia Ross, Chicago State University College of Pharmacy, 2012 - 2013 Capstone project co-advisor, Capstone paper and poster |
Kduse Ragassa, Chicago State University College of Pharmacy, 2013 - 2014 Capstone project co-advisor, Capstone paper and poster |
Nancy El-Sharkawy, Chicago State University College of Pharmacy, 2013 - 2014 Capstone project, Two peer-reviewed publications |
Kwame Owusu-Banahene, Chicago State University College of Pharmacy, 2014 - 2015 Capstone project, Capstone poster and paper |
Nkuti Ndely, Chicago State University College of Pharmacy, 2014 - 2015 Capstone project, Capstone poster and paper |
Hao-Wen Fu, Chicago State University College of Pharmacy, 2014 - 2016 Research elective, Capstone project, Peer-reviewed publication, oral presentation at international meeting, capstone award |
Sharon Chiu, Chicago State University College of Pharmacy, 2014 - 2015 Capstone project, Peer-reviewed publication |
Kristine Manlimos, Chicago State University College of Pharmacy, 2015 - 2016 Capstone co-advisor, Poster presentations at national meetings |
Nidhi Patel, Chicago State University College of Pharmacy, 2015 - 2016 Capstone co-advisor, Poster presentations at national meetings |
COMMUNITY SERVICE ACTIVITIES: |
09/17/2017 2017 Greater Milwaukee Heart & Stroke Walk, Veterans Park, Milwaukee, WI. Donor/Walker Public |
10/08/2017 American Foundation for Suicide Prevention (AFSP) Out of the Darkness Walk, Milwaukee, WI. Donor/Walker |
09/22/2018 Inaugural Cancer Crush Walk/Run, Medical College of Wisconsin, Milwaukee, WI. Donor/Walker |
09/29/2018 2018 Greater Milwaukee Heart & Stroke Walk, Veterans Park, Milwaukee, WI. Donor/Walker |
10/14/2018 American Foundation for Suicide Prevention (AFSP) Out of the Darkness Walk, Milwaukee, WI. Donor/Walker |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Abourashed EA, El-Alfy AT. Chemical diversity and pharmacological significance of the secondary metabolites of nutmeg (<i>Myristica fragrans</i> Houtt.). Phytochem Rev. 2016 Dec;15(6):1035-1056. PMCID: PMC5222521 |
2. Chiu S, Wang T, Belski M, Abourashed EA. HPLC-Guided Isolation, Purification and Characterization of Phenylpropanoid and Phenolic Constituents of Nutmeg Kernel (Myristica fragrans). Nat Prod Commun. 2016 Apr;11(4):483-8. PMCID: PMC4943679 |
3. El-Alfy AT, Joseph S, Brahmbhatt A, Akati S, Abourashed EA. Indirect modulation of the endocannabinoid system by specific fractions of nutmeg total extract. Pharm Biol. 2016 Dec;54(12):2933-2938. |
4. Abourashed EA, Roberson CL, Elsharkawy N. Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements. J Diet Suppl. 2016;13(2):171-84. |
5. Abourashed EA, Abraha A, Khan SI, McCants T, Awan S. Potential of Horse Apple Isoflavones in Targeting Inflammation and Tau Protein Fibrillization. Nat Prod Commun. 2015 Sep;10(9):1577-80. |
6. Osman AMG, Abourashed EA, Slade D, Ahmed SA, Gul W, Khan SI, Abo-Elfadl T, Dale OR, Husni AS, Cutler SJ, ElSohly MA. Synthesis and in Vitro Evaluation of Ferutinol Aryl Esters for Estrogenic Activity and their Affinity Med. Chem. Res.. Osman, A.M.G., Abourashed, E.A., Slade, D. et al. Med Chem Res (2015) 24: 2670. doi:10.1007/s00044-015-1319-7. |
7. Stec J, Abourashed EA. Recently disclosed chemical entities as potential candidates for management of tuberculosis. Pharm Pat Anal. 2015;4(4):317-47. |
8. A Roberson CL, Abourashed EA, Elsharkawy N. Evaluation of cost versus antioxidant determinants in green tea dietary supplements. J Am Pharm Assoc (2003). 2015;55(4):381-9. |
9. Abourashed EA. Bioavailability of Plant-Derived Antioxidants. Antioxidants (Basel). 2013 Nov 05;2(4):309-25. PMCID: PMC4665521 |
10. Darji K, Miglis C, Wardlow A, Abourashed EA. HPLC determination of isoflavone levels in osage orange from the Midwest and southern United States. J Agric Food Chem. 2013 Jul 17;61(28):6806-11. PMCID: PMC3774050 |
11. Abourashed EA, Mikell JR, Khan IA. Bioconversion of silybin to phase I and II microbial metabolites with retained antioxidant activity. Bioorg Med Chem. 2012 May 01;20(9):2784-8. |
12. El-Alfy AT, Abourashed EA, Matsumoto RR. Nature against depression. Curr Med Chem. 2012;19(14):2229-41. |
13. Abourashed EA, Galal AM, Shibl AM. Antimycobacterial activity of ferutinin alone and in combination with antitubercular drugs against a rapidly growing surrogate of Mycobacterium tuberculosis. Nat Prod Res. 2011 Jul;25(12):1142-9. |
14. El-Alfy AT, Wilson L, ElSohly MA, Abourashed EA. Towards a better understanding of the psychopharmacology of nutmeg: Activities in the mouse tetrad assay. J Ethnopharmacol. 2009 Nov 12;126(2):280-6. PMCID: PMC2783227 |
15. Abbas FA, Al-Massarany SM, Khan S, Al-Howiriny TA, Mossa JS, Abourashed EA. Phytochemical and biological studies on Saudi Commiphora opobalsamum L. Nat Prod Res. 2007 May;21(5):383-91. |
16. Abourashed EA, Koetter U, Brattström A. In vitro binding experiments with a Valerian, hops and their fixed combination extract (Ze91019) to selected central nervous system receptors. Phytomedicine. 2004 Nov;11(7-8):633-8. |
17. Abourashed EA, Mossa JS. HPTLC determination of caffeine in stimulant herbal products and power drinks. J Pharm Biomed Anal. 2004 Nov 15;36(3):617-20. |
18. Akgul Y, Ferreira D, Abourashed EA, Khan IA. Lotaustralin from Rhodiola rosea roots. Fitoterapia. 2004 Sep;75(6):612-4. |
19. Schellenberg R, Sauer S, Abourashed EA, Koetter U, Brattström A. The fixed combination of valerian and hops (Ze91019) acts via a central adenosine mechanism. Planta Med. 2004 Jul;70(7):594-7. |
20. Khan SI, Abourashed EA, Khan IA, Walker LA. Transport of harman alkaloids across Caco-2 cell monolayers. Chem Pharm Bull (Tokyo). 2004 Apr;52(4):394-7. |
21. Khan SI, Abourashed EA, Khan IA, Walker LA. Transport of parthenolide across human intestinal cells (Caco-2). Planta Med. 2003 Nov;69(11):1009-12. |
22. Abourashed EA, Vanderplank J, Khan IA. High-Speed Extraction and HPLC Fingerprinting of Medicinal Plants – II. Application to Harman Alkaloids of Genus Passiflora Pharm. Biol.. 2003, 41, 100-106. http://dx.doi.org/10.1076/phbi.41.2.100.14244 . |
23. Abourashed EA, El-Alfy AT, Khan IA, Walker L. Ephedra in perspective--a current review. Phytother Res. 2003 Aug;17(7):703-12. |
24. Abourashed EA, Ganzera M, Khan IA, Khan S, Mossa JS, El-Feraly FS. HPLC fingerprinting and estimation of the bioactive components of Clutia richardiana L. as a potential hypoglycemic herbal tea. Phytother Res. 2003 Jun;17(6):657-60. |
25. Glisson JK, Rogers HE, Abourashed EA, Ogletree R, Hufford CD, Khan I. Clinic at the health food store? Employee recommendations and product analysis. Pharmacotherapy. 2003 Jan;23(1):64-72. |
26. Müller CE, Schumacher B, Brattström A, Abourashed EA, Koetter U. Interactions of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors. Life Sci. 2002 Sep 06;71(16):1939-49. |
27. Abourashed EA, Vanderplank JR, Khan IA. High-Speed Extraction and HPLC Fingerprinting of Medicinal Plants – I. Application to Passiflora Flavonoids Pharm. Biol.. Pharm. Biol., 2002, 40, 81-91. http://dx.doi.org/10.1076/phbi.40.2.81.5844 . |
28. Meazza G, Scheffler BE, Tellez MR, Rimando AM, Romagni JG, Duke SO, Nanayakkara D, Khan IA, Abourashed EA, Dayan FE. The inhibitory activity of natural products on plant p-hydroxyphenylpyruvate dioxygenase. Phytochemistry. 2002 Jun;60(3):281-8. |
29. Abourashed EA, Khan IA. GC determination of parthenolide in feverfew products. Pharmazie. 2001 Dec;56(12):971-2. |
30. Abourashed EA, Galal AM, El-Feraly FS, Khan IA. Separation and quantification of the major daucane esters of Ferula hermonis by HPLC. Planta Med. 2001 Oct;67(7):681-2. |
31. Abourashed EA, Muhammad I, Resch M, Bauer R, el-Feraly FS, Hufford CD. Inhibitory effects of maesanin and analogs on arachidonic acid metabolizing enzymes. Planta Med. 2001 Jun;67(4):360-1. |
32. Abourashed EA, Khan IA. High-performance liquid chromatography determination of hydrastine and berberine in dietary supplements containing goldenseal. J Pharm Sci. 2001 Jul;90(7):817-22. |
33. Khan IA, Allgood J, Walker LA, Abourashed EA, Schlenk D, Benson WH. Determination of heavy metals and pesticides in ginseng products. J AOAC Int. 2001;84(3):936-9. |
34. Galal AM, Abourashed EA, Ross SA, ElSohly MA, Al-Said MS, El-Feraly FS. Daucane sesquiterpenes from Ferula hermonis. J Nat Prod. 2001 Mar;64(3):399-400. |
35. Abourashed EA, Khan IA. Microbial transformation of kawain and methysticin. Chem Pharm Bull (Tokyo). 2000 Dec;48(12):1996-8. |
36. Abourashed EA, Khan IA, Abourashed EA, Khan IA. Determination of parthenolide in selected feverfew products by liquid chromatography. J AOAC Int. 2000;83(4):789-92. |
37. Abourashed EA, el-Feraly FS, Khan IA, Hufford CD. 2-Hydroxy-5-(ethanolamino)-3-(10'-Z-pentadecenyl)-1,4-benzoquinone, new microbial phase II metabolite of maesanin. Chem Pharm Bull (Tokyo). 2000 Jan;48(1):45-7. |
38. Abourashed EA, Toyang NJ, Choinski J Jr, Khan IA. Two new flavone glycosides from paullinia pinnata. J Nat Prod. 1999 Aug;62(8):1179-81. |
39. Abourashed EA, El-Feraly FS, Hufford CD. Carboxylic acid microbial metabolites of the natural benzoquinone, maesanin. J Nat Prod. 1999 May;62(5):714-6. |
40. Abourashed EA, Clark AM, Hufford CD. Microbial models of mammalian metabolism of xenobiotics: An updated review. Curr Med Chem. 1999 May;6(5):359-74. |
41. E.A. Abourashed
C.D. Hufford. Microbial Transformation of Artemether J. Nat. Prod.. J. Nat. Prod., 1996, 59 (3), pp 251–253. |
42. Abourashed EA, Fu HW. Hydroxybenzoic Acids Are Significant Contributors to the Antioxidant Effect of Borututu Bark, Cochlospermum angolensis Welw. ex Oliv. Antioxidants (Basel). 2017 Jan 28;6(1). PMCID: PMC5384172 |
43. Pertzborn M, Obradovich J, Bhathena S, Sperry A, Abourashed EA. Cause or Consequence? The Role of Heroin in the Opioid Epidemic, and Pharmacists as Frontline Responders. The Journal of the Pharmacy Society of Wisconsin 2019, 22, 30-34. |
44. Abourashed EA and Cross W. A Sustained Elective Course on Substance Abuse and Addiction Delivered in an Academic Pharmacy Programme. Pharmacy Education, 2019, 19, 190-198. |
45. Kadi A, Hefnawy M, Al-Majed A, Alonezi S, Asiri Y, Attia S, Abourashed EA, El-Subbagh H. Liquid Chromatographic High-Throughput Analysis of the New Ultra-short Acting Hypnotic ‘HIE-124’ and its Metabolites in Mice Serum Using a Monolithic Silica Column. Analyst, 2011, 136, 591-597. |
46. Hefnawy M, Al-Omar M, Julkhufa S, Attia S, Abourashed E, El-Subbagh H.Novel, Selective Sample Stacking Microemulsion Electrokinetic Capillary Chromatography Induced by Reverse Migrating Pseudostationary Phase for the Determination of the New Ultra-Short Acting Hypnotic “HIE-124” in Mice Serum. Analytica Chimica Acta, 2010, 673, 194–199. |
47. Abourashed EA, Hefnawy MM, El-Subbagh HI. HPTLC Determination of a New Ultra-Short-Acting Thiazolodiazepine Hypnotic (HIE-124) in Spiked Human Plasma. J. Planar Chromatogr., 2009, 22, 183–186. |
48. El-Massarany SM, Abbas FA, Demirci B, Baser KHC, Khan SI, Al-Rehaily AJ, Mossa JS, Abourashed EA. Chemical Composition and Biological Evaluation of the Essential Oil of Commiphora opobalsamum L. J. Herbs Spices Med. Plants, 2007, 13, 109-121. |
49. Abourashed EA, Galal AM, Shebl AM, Mossa JS. Enhancing Effect of Isoeugenol on the Antimicrobial Activity of Isoniazid, 6-Paradol and 6-Shogaol. J. Herbs Spices Med. Plants, 2007, 13, 95-103. |
50. Abourashed EA. Thin-layer Densitometry as an Alternative Tool in the Quantitative Evaluation of the Free Radical Scavenging Activity of Natural Antioxidants. Z. Naturfortsch., 2005, 60b, 1212-1218. |
51. Abourashed EA, Abdel-Kader MS, Habib AM. HPTLC determination of sildenafil in pharmaceutical products and aphrodisiac herbal preparations. J. Planar Chromatogr., 2005, 18, 372-376. |
52. Abourashed EA. Validation and application of an HPTLC method for the determination of parthenolide in feverfew herbal products.J. Planar Chromatogr., 2004, 17, 375-378. |
53. El-Alfy AT, Abourashed EA, Patel C, Mazhari N, An H, Jeon A. Phenolic compounds from nutmeg (Myristica fragrans Houtt.) inhibit the endocannabinoid-modulating enzyme fatty acid amide hydrolase. J Pharm Pharmacol. 2019 Dec;71(12):1879-1889. PMCID: PMC7938946 |
54. Cramer J, Bevry M, Handler S, Tillman K, Abourashed EA. Stability Determination of an Extemporaneously Compounded Ambrisentan Suspension by High Performance Liquid Chromatography Analysis. J Pediatr Pharmacol Ther. 2021;26(3):265-270. PMCID: PMC8021248 |
55. Abourashed EA, Kutty RG, Bevry M, Hoffmann P. Retained strength of expired albuterol and montelukast pharmaceuticals Annals of Allergy, Asthma and Immunology. 2021. |
56. Abourashed EA, Cross W. A sustained elective course on substance abuse and addiction delivered in an academic pharmacy programme Pharmacy Education. 2019;19(1):190-198. |
57. Abourashed EA. Review of Stilbenes: Applications in Chemistry, Life Sciences and Materials Science Journal of Natural Products. 24 February 2017;80(2):577. |
58. Osman AMG, Abourashed EA, Slade D, Ahmed SA, Gul W, Khan SI, Elfadl TA, Dale OR, Husni AS, Cutler SJ, Elsohly MA. Synthesis and in vitro evaluation of ferutinol aryl esters for estrogenic activity and affinity toward cannabinoid receptors Medicinal Chemistry Research. 11 June 2015;24(6):2670-2678. |
59. Kadi A, Hefnawy M, Al-Majed A, Alonezi S, Asiri Y, Attia S, Abourashed E, El-Subbagh H. Liquid chromatographic high-throughput analysis of the new ultra-short acting hypnotic 'HIE-124' and its metabolite in mice serum using a monolithic silica column Analyst. 7 February 2011;136(3):591-597. |
60. Hefnawy M, Al-Omar M, Julkhuf S, Attia S, Abourashed E, El-Subbagh H. Novel, selective sample stacking microemulsion electrokinetic capillary chromatography induced by reverse migrating pseudostationary phase for the determination of the new ultra-short acting hypnotic "HIE-124" in mice serum. Anal Chim Acta. 2010 Jul 19;673(2):194-9. |
61. Abourashed E, Hefnawy M, El-Subbagh H. HPTLC analysis of a new ultra-short-acting thiazolodiazepine hypnotic (HIE-124) in spiked human plasma Journal of Planar Chromatography - Modern TLC. 1 June 2009;22(3):183-186. |
62. Al-Massarany SM, Abbas FA, Demirci B, Baser KHC, Khan SI, Al-Rehaily AJ, Mossa JS, Abourashed EA. Chemical composition and biological evaluation of the essential oil of Commiphora opobalsamum L. Journal of Herbs, Spices and Medicinal Plants. 28 April 2008;13(4):111-121. |
63. Abourashed EA, Galal AM, Shebl AM, Mossa JS. Enhancing effect of isoeugenol on the antimicrobial activity of isoniazid, 6-paradol and 6-shogaol Journal of Herbs, Spices and Medicinal Plants. 28 April 2008;13(4):95-103. |
64. Abourashed EA, Abdel-Kader MS, Habib AAM. HPTLC determination of sildenafil in pharmaceutical products and aphrodisiac herbal preparations Journal of Planar Chromatography - Modern TLC. September 2005;18(105):372-376. |
65. Abourashed EA. Thin-layer densitometry as an alternative tool in the quantitative evaluation of the free radical scavenging activity of natural antioxidants Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences. November 2005;60(11):1212-1218. |
66. Abourashed EA. Validation and application of an HPTLC method for the determination of parthenolide in feverfew herbal products Journal of Planar Chromatography - Modern TLC. September 2004;17(5):375-378. |
67. Abourashed EA, Vanderplank J, Khan IA. High-speed extraction and HPLC fingerprinting of medicinal plants - II. Application to harman alkaloids of genus Passiflora Pharmaceutical Biology. April 2003;41(2):100-106. |
68. Abourashed EA, Vanderplank JR, Khan IA. High-speed extraction and HPLC fingerprinting of medicinal plants - I. Application to Passiflora flavonoids Pharmaceutical Biology. 2002;40(2):81-91. |
69. Abourashed EA, Hufford CD. Microbial transformation of artemether Journal of Natural Products. March 1996;59(3):251-253. |
Books, Chapters, and Reviews |
1. Leung’s Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. 3rd Ed. IA Khan and EA Abourashed Eds. Wiley, New Jersey, 2009. |
Non-Refereed Journal Publications/Original Papers |
1. Abourashed EA. Review of Discovery and Development of Neuroprotective Agents from Natural Products. Journal of Natural Products, 2018, 81, 1917-1918. |
2. Abourashed EA. J. Nat. Prod., 2017, 80, 577. “Review of Stilbenes: Applications in Chemistry, Life Sciences and Materials Science”. |
3. Abourashed EA. HerbalGram 2013, 97, 73-74. “Greco-Arab and Islamic Herbal Medicine: Traditional Systems, Ethics, Safety, Efficacy, and Regulatory Issues, by Bashar Saad and Omar Said”. |
4. Abourashed EA. HerbalGram 2012, 95, 69-70. “Encyclopedia of Islamic Herbal Medicine, by John A. Marrow”. |
5. Abourashed EA. J. Nat. Prod., 2010, 73, 1460. “Review of Bioactive Natural Products−Detection, Isolation, and Structural Determination, by Steven M. Colegate and Russell J. Molyneux”. |
6. Abourashed EA. HerbalGram 2009, 82, 68. “Arab/American: Landscape, Culture, and Cuisine in Two Great Deserts, by Gary P. Nabhan”. |
7. Abourashed EA. Saudi Pharm. J. 2006, 14, 136-137. “ACD/ChemSketch 8.0 for Windows, Advanced Chemistry Development Inc.”. |
8. Abourashed EA. Saudi Pharm. J. 2005, 13(1), 61-62. “The Handbook of Clinically Tested Herbal Remedies, Vol 1 & 2, edited by Marilyn Barrett”. |
9. Abourashed EA. Saudi Pharm. J. 2005, 13, 200-201. “Reference Manager for Windows, ver. 11, ISI Researchsoft”. |
10. Abourashed EA. Saudi Pharm. J. 2005, 13, 201-202. “The ABC Clinical Guide to Herbs, by Mark Blumenthal”. |
11. Abourashed EA. J. Nat. Prod. 2004, 67, 1771-1772. “Review of Medicinal Plants of the World, 2nd Edition, Vol. 1, by Ivan A. Ross”. |
Patents |
1. Method of Modulating the Endocannabinoid System through Pure Compounds from Nutmeg for Treatment of Psychiatric Conditions. EA Abourashed and AT El-Alfy. U.S. provisional patent, December 15, 2014.
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