CURRICULUM VITAE
Emma A. Morrison PhD
Emma A. Morrison PhD
Assistant Professor
Department of Biochemistry
Department of Biochemistry
OFFICE ADDRESS: |
Translational and Biomedical Research Center |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Halstead MF, Ajtai K, Penheiter AR, Spencer JD, Zheng Y, Morrison EA, Burghardt TP. An unusual transduction pathway in human tonic smooth muscle myosin. Biophys J. 2007 Nov 15;93(10):3555-66. PMCID: PMC2072059 |
2. Morrison EA, DeKoster GT, Dutta S, Vafabakhsh R, Clarkson MW, Bahl A, Kern D, Ha T, Henzler-Wildman KA. Antiparallel EmrE exports drugs by exchanging between asymmetric structures. Nature. 2011 Dec 18;481(7379):45-50. PMCID: PMC3253143 |
3. Morrison EA, Henzler-Wildman KA. Reconstitution of integral membrane proteins into isotropic bicelles with improved sample stability and expanded lipid composition profile. Biochim Biophys Acta. 2012 Mar;1818(3):814-20. PMCID: PMC3292179 |
4. Morrison EA, Henzler-Wildman KA. Transported substrate determines exchange rate in the multidrug resistance transporter EmrE. J Biol Chem. 2014 Mar 07;289(10):6825-6836. PMCID: PMC3945343 |
5. Dutta S, Morrison EA, Henzler-Wildman KA. EmrE dimerization depends on membrane environment. Biochim Biophys Acta. 2014 Jul;1838(7):1817-22. PMCID: PMC4061694 |
6. Dutta S, Morrison EA, Henzler-Wildman KA. Blocking dynamics of the SMR transporter EmrE impairs efflux activity. Biophys J. 2014 Aug 05;107(3):613-620. PMCID: PMC4129506 |
7. Morrison EA, Robinson AE, Liu Y, Henzler-Wildman KA. Asymmetric protonation of EmrE. J Gen Physiol. 2015 Dec;146(6):445-61. PMCID: PMC4664823 |
8. Morrison EA, Sanchez JC, Ronan JL, Farrell DP, Varzavand K, Johnson JK, Gu BX, Crabtree GR, Musselman CA. DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes. Nat Commun. 2017 Jul 14;8:16080. PMCID: PMC5519978 |
9. Robinson AE, Thomas NE, Morrison EA, Balthazor BM, Henzler-Wildman KA. New free-exchange model of EmrE transport. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10083-E10091. PMCID: PMC5703289 |
10. Morrison EA, Bowerman S, Sylvers KL, Wereszczynski J, Musselman CA. The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome. Elife. 2018 Apr 12;7. PMCID: PMC5953545 |
11. Thomas NE, Wu C, Morrison EA, Robinson AE, Werner JP, Henzler-Wildman KA. The C terminus of the bacterial multidrug transporter EmrE couples drug binding to proton release. J Biol Chem. 2018 Dec 07;293(49):19137-19147. PMCID: PMC6295725 |
12. Li Y, Xie N, Chen R, Lee AR, Lovnicki J, Morrison EA, Fazli L, Zhang Q, Musselman CA, Wang Y, Huang J, Gleave ME, Collins C, Dong X. RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression. Eur Urol. 2019 Aug;76(2):157-166. |
13. Morrison EA, Baweja L, Poirier MG, Wereszczynski J, Musselman CA. Nucleosome composition regulates the histone H3 tail conformational ensemble and accessibility. Nucleic Acids Res. 2021 May 07;49(8):4750-4767. PMCID: PMC8096233 |
14. Lupo BE, Chu P, Harms MJ, Morrison EA, Musselman CA. Evolutionary Conservation of Structural and Functional Coupling between the BRM AT-Hook and Bromodomain. J Mol Biol. 2021 Jul 09;433(14):166845. PMCID: PMC8184587 |
15. Hammonds EF, Harwig MC, Paintsil EA, Tillison EA, Hill RB, Morrison EA. Histone H3 and H4 tails play an important role in nucleosome phase separation. Biophys Chem. 2022 Apr;283:106767. PMCID: PMC8963862 |
16. Paintsil EA, Morrison EA. Preparation of Recombinant Histones and Widom 601 DNA for Reconstitution of Nucleosome Core Particles. Methods Mol Biol. 2023;2599:163-175. |
17. Hammonds EF, Morrison EA. Nucleosome Core Particle Reconstitution with Recombinant Histones and Widom 601 DNA. Methods Mol Biol. 2023;2599:177-190. |
18. Jennings CE, Zoss CJ, Morrison EA. Arginine anchor points govern H3 tail dynamics. Front Mol Biosci. 2023;10:1150400. PMCID: PMC10228543 |
Books, Chapters, and Reviews |
1. Morrison EA, Musselman CA. The role of PHD fingers in chromatin signaling: mechanisms and functional consequences of the recognition of histone and non-histone targets. In Chromatin Signaling, Binda, O. and Fernandez-Zapico, M. (Eds.), Elsevier (2016). |
2. Weaver TM, Morrison EA, Musselman CA. Reading More than Histones: The Prevalence of Nucleic Acid Binding among Reader Domains. Molecules. 2018 Oct 12;23(10). PMCID: PMC6222470 |
