CURRICULUM VITAE
Heidi T. Zafra MD
Heidi T. Zafra MD
Professor
Department of Pediatrics
Division of Allergy
Associate Professor in Pediatrics and Medicine
Division of Allergy/ Clinical Immunology
Asthma Allergy Section Chief; Children’s Wisconsin (CW)
Department of Pediatrics
Division of Allergy
Associate Professor in Pediatrics and Medicine
Division of Allergy/ Clinical Immunology
Asthma Allergy Section Chief; Children’s Wisconsin (CW)
OFFICE ADDRESS: |
Children’s Wisconsin - Specialty Clinics Building |
8915 W Connell Court |
Milwaukee, WI 53226 |
EDUCATION: |
06/1982 - 03/1986 BS, University of the Philippines, Philippines |
06/1986 - 03/1990 MD, University of the East, Philippines |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
05/1990 - 04/1991 Post Graduate Rotating Internship, St. Luke’s Medical Center, Manila, Philippines |
06/1993 - 06/1996 Resident, Pediatrics, North Shore University Hospital, Manhasset, NY |
07/1996 - 06/1998 Fellowship, Allergy/Immunology, Cornell University Medical Center, New York, NY |
FACULTY APPOINTMENTS: |
07/1996 - 06/1998 Clinical Instructor, Division of Allergy, Immunology and Pulmonology, Cornell University Medical College, New York, NY |
07/1998 - 06/2001 Assistant Professor, Pediatrics, Allergy, MCP-Hahnemann School of Medicine, Philadelphia, PA 19134 |
07/2001 - 06/2015 Assistant Professor, Pediatrics and Medicine, Allergy/ Immunology, Medical College of Wisconsin, 9000 W. Wisconsin Ave., Suite 440, Milwaukee, WI 53226 |
07/2015 - Present Associate Professor, Pediatrics and Medicine, Allergy/ Immunology, Medical College of WI, 9000 W. Wisconsin Ave, Suite 440, Milwaukee, WI 53226 |
ADMINISTRATIVE APPOINTMENTS: |
07/1999 - 06/2001 Director, Subsection of Allergy, Section of Pulmonology and Allergy, St. Christopher’s Hospital for Children, Philadelphia, PA |
07/2001 - 06/2003 Director, St. Christopher’s Hospital for Children, The Asthma Center, Philadelphia, PA |
01/2013 - 09/2016 Director of Immunotherapy, Pediatrics, Allergy/ Immunology, Children's Hospital of Wisconsin, 9000 W. Wisconsin Ave, Suite 440, Milwaukee, WI 53226 |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
07/1999 - 06/2001 Course Director, Pediatrics, Pediatric Allergy, MCP-Hahnemann School of Medicine, Philadelphia, PA |
06/2002 - 06/2007 Director of Allergy/ Immunology Resident Education (Pediatrics), Medical College of Wisconsin, Milwaukee, WI |
06/2007 - 09/2016 Associate Fellowship Program Director, Pediatrics, Allergy/ Immunology, Medical College of Wisconsin, 9000 W. Wisconsin Ave, Suite 440, Milwaukee, WI 53226 |
10/2008 - 09/2016 CME Activity Director, Pediatrics, Division of Allergy/ Immunology, Medical College of Wisconsin, 9000 W. Wisconsin Ave, Suite 440, Milwaukee, WI 53226 |
10/2013 - 04/2018 Director, Annual Program Fellowship Evaluation Committee, Pediatrics, Allergy/ Immunology, Medical College of WI, Suite 440, Suite 440, Milwaukee, WI 53226 |
09/2016 - 04/2018 Fellowship Program Director, Pediatrics, Allergy/ Immunology, Medical College of WI, 9000 W. Wisconsin Ave., Suite 440, Milwaukee, WI 53226 |
HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS: |
02/2021 - Present Asthma Allergy Section Chief, Pediatrics, Allergy/ Immunology, Children's Wisconsin, 9000 W. Wisconsin Ave, Suite 440, Milwaukee, WI 53226 |
RESEARCH ADMINISTRATIVE APPOINTMENTS: |
02/2021 - Present Director, Clinical Research Trials, Pediatrics, Allergy/ Immunology, Medical College of WI, 9000 W. Wisconsin Ave., Suite 440, Milwaukee, WI 53226 |
HOSPITAL STAFF PRIVILEGES: |
07/1998 - 06/2001 St. Christopher’s Hospital for Children, Erie Avenue at Front Street, Philadelphia, PA 19134 |
07/2001 - Present Clement J. Zablocki VA Medical Center, 5000 W. National Ave., Milwaukee, WI 53295 |
07/2001 - Present Children’s Hospital of Wisconsin, 9000 W. Wisconsin Avenue, Milwaukee, WI 53226 |
07/2001 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226 |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
American Board of Pediatrics | 10/1996 | 10/2010 |
American Board of Allergy and Immunology | 09/2001 | 12/2031 |
Licensure | Number | Issue Date | Expiration |
New Jersey License (inactive) | MA066232 | 07/01/1999 | 06/30/2001 |
Pennsylvania License (inactive) | MD064828L | 11/01/2000 | 12/31/2002 |
Wisconsin License | 43348-020 | 05/31/2001 | 10/31/2023 |
AWARDS AND HONORS: |
05/2001 “Top Docs for Kids” for Allergy , Philadelphia Magazine |
02/2005 - 2006 "Top Physicians 2004-2005", Consumer's Research Council of America |
2010 - 2014 Best Doctors in America |
2012 - 2022 Best Doctors, M Magazine |
2016 - 2022 Top Doctors, Castle Conolly, Milwaukee Magazine |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
07/1993 - Present American Academy of Pediatrics (Fellow) |
07/1996 - Present American College of Allergy, Asthma and Immunology (Fellow) |
07/1996 - Present American Academy of Allergy, Asthma and Immunology (Fellow) |
07/1998 - 07/2001 Philadelphia Allergy Society (Member) |
07/2001 - Present Wisconsin Allergy Society (Member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Journal Review |
02/2021 - Present Reviewer, Annals of Allergy, Asthma and Immunology |
Ad-Hoc Reviewer |
09/2018 - Present Grant Reviewer, Clinical and Translational Science Institute (CTSI) of Southeastern Wisconsin Pilot Award Program |
02/2021 - Present Reviewer, American College of Allergy, Asthma and Immunology (ACAAI) Fellow in Training Board Review Case Vignettes |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
06/2013 - 09/2016 Member, Leadership Board, American Lung Association (ALA), Wisconsin Chapter |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
03/2003 - Present Member, Food Allergy, Anaphylaxis, Dermatology and Drug Allergy (ADDA) Interest Section, American Academy of Allergy, Asthma and Immunology |
03/2003 - 2013 Member, Rhinitis Committee, American Academy of Allergy, Asthma and Immunology |
01/2008 - 2016 Member, Atopic Dermatitis/ Eczema Committee, American Academy of Allergy, Asthma and Immunology |
09/2016 - 04/2018 Member, Program Director's Assembly, American Academy of Allergy, Asthma and Immunology |
02/2018 - Present Member, Health Outcomes, Education, Quality and Delivery Interest Section, American Academy of Allergy, Asthma and Immunology |
11/2019 - Present Member, Biologics and Pharmacology Committee, Thymic Stromal Lymphopoietin (TSLP) Subcommittee, American College of Allergy, Asthma and Immunology |
11/2019 - Present Member, Immunotherapy and Diagnostics Committee, American College of Allergy, Asthma and Immunology |
08/2020 - Present Invited Member, Advisory Board, Takeda Pharmaceuticals Advisory Board |
03/2021 - Present Invited Member, Advisory Board, Biocryst Pharmaceuticals |
02/2022 - Present Invited Member, Data Monitoring Committee, European Pediatric Berotralstat Study, Biocryst Pharmaceuticals |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
Zafra H, Practical and Effective Asthma Care, Philippine Medical Society, Philadelphia, PA, 06/11/1999 |
Zafra, H, COVID Myths and Facts, Colegio de Sta. Rosa '82 Health Seminar, (Zoom) Manila, Philippines, 04/23/2021 |
National |
Kelly B, Bauer CS, Nugent ML, Kelly KJ, Gimenez L, Zafra H., The Pediatric Asthma Adherence Test (PAAT): A Survey for Pediatric Patient Propensity to Adhere to Controller Medications (Oral Presentation), Presentation at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Atlanta, GA, 11/06/2014 |
Gobin K*, Sheppard K, Chiu A, Zafra H, Quality Improvement Survey
Assessing Immunotherapy Efficacy and Barriers in an Outpatient Setting (Oral Presentation), Presentation at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Boston, MA, 10/28/2018 |
Regional |
Zafra H, Allergy Case Discussions, The Forty Eighth Annual St. Christopher’s Hospital For Children Update Pediatrics, Philadelphia, PA, 06/09/1999 |
Zafra H, New Options for Asthma Management, Forty-Ninth Annual St. Christopher’s Hospital For Children Update Pediatrics, Philadelphia, PA, 05/23/2000 |
Zafra H, The Dual Components of Asthma and the Benefits of Combination Therapy, Easton Hospital First Annual Pediatric Seminar, Easton, PA, 11/29/2000 |
Zafra H, New Therapies for Asthma Management, Reading Hospital Pediatric Seminar, Reading, PA, 01/05/2001 |
Zafra H, Current Concepts in Pediatric Respiratory Disease, Capital Health Systems, Trenton, NJ, 06/08/2001 |
Understanding the New Asthma Guidelines, American Academy of Pediatrics, Wisconsin Chapter, Milwaukee, WI, 04/19/2008 |
Zafra H, Asthma Overview and Pathophysiology, American Lung Association (ALA) Asthma Educators Program, Asthma Educator Institute, Wheaton Health, Milwaukee, WI, 11/09/2012 - 12/09/2015 |
Zafra H, Improving Asthma Outcomes, American Lung Association Lung Expo, Milwaukee, WI, 07/16/2015 |
Local |
Zafra H, A New Treatment for Asthma, Anti-IgE, Grand Rounds, St. Christopher’s Hospital for Children, Philadelphia, PA, 08/21/1998 |
Zafra H, Anaphylaxis Urticaria and Angioedema, MCP-Hahnemann School of Medicine, Philadelphia, PA, 10/01/1998 |
Zafra H, EIB: Diagnosis and Management, Dept of Sports Medicine, Medical College of WI, Milwaukee, WI, 06/14/2011 |
Zafra H, Understanding the New Asthma Guidelines, Southwest Pediatrics, New Berlin, WI, 04/16/2012 |
Zafra H, Improving Asthma Outcomes, Children's Health Alliance Office, Milwaukee, WI, 07/16/2015 |
Zafra H, Personalizing Asthma Control in Clinical Practice, Children's Specialty Group Lectures, Milwaukee, WI, 07/2015 - 10/2015 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
National |
Healy CT*, Zafra H, Zacharisen MC, Thyroid goiter masquerading as asthma, Abstracts: Poster Sessions, American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, San Antonio, TX, 11/10/2002 - 11/15/2002 |
Duke RL*, Kidder T, Zafra H, Idiopathic anaphylaxis associated with sialoadenitis, Annual meeting of the American Academy of Otolaryngic Allergy Foundation (AAOAF), Orlando, FL, 09/2003 |
Vasudev M, Martinez A, Levy MB, Zafra H, Severe Cow’s Milk Protein Sensitivity in a Child with C. Difficile Colitis, Abstracts: Poster Sessions, American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Philadelphia, PA, 11/2006 |
Buelow B, Lee C, Zafra H, Dasgupta M, Hoffmann R, Vasudev M, The Majority of Egg Allergic Patients Tolerate Egg Baked in Product at Oral Food Challenge, Abstracts: Poster Sessions, American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Baltimore, MD, 11/07/2013 |
Buelow B, Kelly B, Zafra H, Kelly KJ, The value of BAL in Acute Eosinophilic Pneumonia of Allen, Abstracts: Poster Sessions, American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Baltimore, MD, 11/07/2013 - 11/11/2013 |
Buelow B, Zafra H, The Diagnosis is in the History: A Case of DRESS in a Pediatric Patient, American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Atlanta, GA, 11/06/2015 - 11/10/2015 |
Kelly B, Bauer CS, Nugent ML, Simpson PM, Kelly KJ, Gimenez LM, Zafra H, The Pediatric Asthma Adherence Test (PAAT): A Survey for Pediatric Patient Propensity to Adhere to Controller Medications, Abstract and Oral Presentation at American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Atlanta, GA, 11/06/2015 - 11/10/2015 |
Tallar M , Chen W, Gallagher M, Gedeit R, and Zafra H, Compartment Syndrome Requiring Fasciotomy in a Patient with HAE Type 1: a Case Report, Abstracts: Poster Sessions, American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Atlanta, GA, 11/06/2015 - 11/10/2015 |
Peloza D, Gimenez L, Crandall L, Nugent M, Simpson P, Zafra H, Pediatric Asthma Adherence Test, Abstracts: Poster Sessions, American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, San Francisco, CA, 11/10/2016 - 11/14/2016 |
Gobin, K, Sheppard K, Chiu A, Zafra H, Quality Improvement Survey Assessing Immunotherapy Efficacy and Barriers in an Outpatient Setting, Abstract and Oral Presentation, American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Boston, MA, 10/26/2017 - 10/30/2017 |
Bashir M, Zafra H, Sebelipase Desensitization: A Case Report, Poster Sessions, American Academy of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, Orlando, FL, 03/02/2018 - 03/05/2018 |
Sexton D, Brown N, Lumry W, Gower G, Hao J, Lu P, Zafra H, Lanadelumab And Cardiovascular Risk: Findings From The Phase 3 HELP Study, Abstracts: Poster Sessions, American Academy of Allergy, Asthma and Immunology (AAAAI) Scientific Meeting, San Francisco, CA, 02/22/2019 - 02/25/2019 |
Regional |
Sova C, Feuling M, Baumier M, Gleason L, Tam J, Tam J, Zafra H., Goday P, Changes in Calcium Intake in Children with Multiple Food Allergies that Received Medical Nutrition Therapy, Wisconsin Academy of Nutrition and Dietetics Annual Conference, Milwaukee, WI, 04/18/2013 |
Local |
Bauer CS, Chiu AM, Zafra H, Gimenez LM, Nugent ML, Simpson PM, Vasudev M, . "Why Should I Rotate in Allergy and Clinical Immunology During Medical School or Residency?, Department of Pediatrics, The Joint Fellowship Curriculum (JFC) Committee Research Day, Medical College of Wisconsin, Milwaukee, WI, 04/2013 |
McKenny A, Zafra H., Oral Methotrexate Desensitization: A Case Report, Diversity Summer Health- Related Research Education Program (DSHREP), Medical College of Wisconsin, Milwaukee, WI, 08/05/2021 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
06/2007 - 2010 Member, Library Committee, Medical College of Wisconsin |
10/2009 - 2010 Member, Library White Paper Subgroup, Medical College of Wisconsin |
01/2010 Member, Internal Review Committee, Pediatric Endocrinology Fellowship Program, Medical College of Wisconsin |
11/2011 Member, Fellowship Work Group, Allergy/ Immunology, Pediatrics, Medical College of WI |
2012 - Present Member, Intern Selection Committee, Pediatrics, Medical College of WI |
04/2013 - 06/2013 Member, ERVU Education Advisory Committee, Pediatrics, Medical College of WI |
08/2013 - 07/2016 Member, Faculty Council, Pediatrics, Medical College of WI |
11/2020 - Present Member, Justice, Equity, Diversity and Inclusion, Workforce Subcommittee, Pediatrics, Medical College of WI |
Hospital |
03/2011 - 04/2012 Member, CSG Quality Committee, Pay for Performance Subcommittee, Children's Wisconsin |
03/2012 - 07/2012 Member, Vaccine Clinic Implementation Planning, Children's Wisconsin |
11/2014 - 06/2020 Member, Emergency Preparedness Committee, Allergy/ Immunology, Pediatrics, Children's WI |
03/2016 - 09/2016 Member, CHW Immunotherapy Quality Improvement, Allergy/ Immunology, Pediatrics |
02/2018 - Present Member, Pharmacy and Therapeutics Committee, Pediatrics, Children's Wisconsin |
04/2019 - 2020 Member, Translational / Clinical Research Advisory Committee, Pediatrics, Children's Wisconsin |
02/2021 - Present Member, CW Joint Patient Care Committee (JPCC), Pediatrics |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
09/2004 Immunology Review |
11/18/2009 - 2014 M2 Clinical Exam and Reasoning Course (CER) Preceptor, Teach Physical Exam findings (4 hours/ year) |
01/2011 M1 Cardivascular/ Respiratory/ Renal (CVRR) Module Moderator |
07/2011 - Present Apprenticeship in Medicine (AIM), for undergraduate/ high school students |
07/2012 - 06/2013 Ambulatory Immersion Rotation |
01/2013 - 05/2013 M1 Clinical Apprenticeship Course |
02/2014 M2 Bench-to-Bedside ENT clinical skills workshop |
03/2021 - Present ReasearchOpportunity for Academic Development in Science (for undergraduate/ high school students) |
Resident and Fellow Education |
2001 - 2008 Ace the Boards, Allergy/ Immunology Review Course for Pediatric Board Examinations |
2007 - 2010 Vasculitis/ Rheumatology, Allergy/ Immunology Mini-Lectures |
2007 - 2009 Insect Allergy, Allergy/ Immunology Mini-Lectures |
2007 - 2015 Allergic Diseases in Pregnancy, Allergy/ Immunology Mini-Lectures |
2009 - Present Allergy/ Immunology Journal Club |
2011 - 2019 Immunomodulators, Allergy/ Immunology Mini-Lectures |
06/2013 Annual Procedure Workshop for Interns |
06/2013 - 06/2016 MCWAH House Staff Orientation |
08/2014 Noon Conference, Pediatrics |
Continuing Medical Education |
11/17/2005 Gender Related Differences in Allergy/ Asthma, Allergy/ Immunology Grand Rounds |
09/2006 - 05/30/2008 Complementary and Alternative Medicine, Allergy/ Immunology Grand Grounds |
2007 - 2013 Aeroallergens, Allergy/ Immunology Grand Rounds |
2014 - 2017 Aeroallergens and Immunotherapy, Allergy/ Immunology Grand Rounds |
2018 - 2020 Hereditary Angioedema, Allergy/ Immunology Grand Rounds |
02/21/2020 - Present Biologics in Asthma, Allergy/ Immunology Grand Rounds |
EXTRAMURAL TEACHING: |
Community/Lay Public |
11/2004 Schoeder YMCA, Milwaukee, WI, Exercise and Asthma (Community Education Class) |
06/2005 Women's Wellness Wednesday, Wisconsin Athletic Club, Allergic Rhinitis and Sinusitis (Community Education Class) |
07/2010 Community Memorial Hospital, Menomonee Falls, WI, Asthma and Allergies (Community Education Class) |
Nursing Student Education |
08/05/2009 Children's Wisconsin, Insect Allergy Lecture for Nursing Staff Teaching lecture for the nurses and medical assistants of the Allergy Clinic |
02/2012 - 02/2013 Children's Wisconsin, Nursing Staff Competency Training on Immunotherapy |
PROGRAMMATIC DEVELOPMENTS: |
Educational Programs |
Fellow |
07/2008 - 09/2016 Associate Program Director, organized the educational, clinical and research activities from a 2yr to 3yr program |
09/2016 - 04/2018 Program Director, Revision of Allergy/ Immunology
Fellowship Program Curriculum
|
Faculty |
07/2008 - 09/2016 CME Activity Director, coordinated and completed CME Program Compliance requirements, invited speakers |
2010 - Present Jordan Fink Lecture Series, organizer and coordinator (invite a nationally recognized speaker annually) |
Clinical Programs |
11/2010 - 12/2011 Launched a Children's WI/ Froedtert Hospital/ Community Memorial Clinic (Developed an EMR system specifically tailored for Allergy/ Immunology |
01/2012 - 2012 Revision Allergen Immunotherapy Safety Protocols |
04/2012 - 2012 Development of Omalizumab Guidelines |
07/2012 - 2012 Development of Aspirin Desensitization Guidelines |
12/2012 - 2012 Development of Baked Egg Food Challenge Guidelines |
04/2013 - 2013 Revision the Asthma/Allergy Clinics Anaphylaxis Protocol |
01/2014 - 2014 Improving Efficacy of Immunotherapy Prescriptions (Revision of Immunotherapy) |
02/2014 - 2014 QI PRoject: Meta-analysis of anaphylaxis events in the Asthma/ Allergy Clinics |
02/2016 - 2018 Development and Revision of the Immunotherapy Send Out Guidelines |
11/2017 - 2017 QI Project: Quality Improvement Survey Assessing Immunotherapy Efficacy and Barriers in an Outpatient Setting (CW Value Champions Project) |
03/2018 - 2018 QI Project: Quality Improvement PRoject on Fellow Proficiency in Writing Allergen Immunotherapy Prescriptions |
Community Programs |
2009 - 2013 Nationwide Asthma Screening Program, sponsored by the American College of Allergy, Asthma and Immunology (ACAAI) |
COMMUNITY SERVICE ACTIVITIES: |
06/2013
American Lung Association Active with Asthma Day Camp (Volunteer Staff), Bayview High School, Milwaukee, WI.
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10/2013 American Lung Association Fight for Air Walk (Guest Speaker and Participant), Milwaukee, WI.
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05/2015 05/2015 American Lung Association (ALA) Lung Expo Planning Committee Member and volunteer, Italian Community Center, Milwaukee, WI.
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2018 - Present University School of Milwaukee (USM) parent volunteer for high school tennis, ski team and lacrosse
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2018 - Present Milwaukee Folk Fair volunteer, Philippine booth |
CLINICAL INVESTIGATION/CLINICAL STUDIES: |
07/1996 - 06/1997 A Phase II, Multi-Center, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Anti-IgE Recombinant Humanized Monoclonal Antibody (rhuMAb-E25) in Patients with Moderate to Severe Allergic Asthma.
Sub-Investigator.
(Genentech, Inc.)
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01/1997 - 06/1998 Rhinoconjunctivitis Quality of Life Questionnaire among
Hispanics MAPI Research Institute
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06/1997 - 06/1998 A Randomized, Open Label, Cross-Over Study Comparing Parent-Guardian Preference for Montelukast Sodium Tablets or Cromolyn Aerosol (MDI) Treatment in their Children ages 6 to 11 with Chronic Asthma.
Sub-Investigator.
(Merck)
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01/2001 - 06/2001 A Multicenter, Randomized, Double-blind, Parallel-group, Placebo-Controlled, 12-Week study of Fluticasone mcg BID delivered via CFC MDI and a Valved Holding Chamber with Facemask in Subjects with Asthma age 24 Months to 47 months, 6 Months to 23 Months.
Sub-Investigator.
(GlaxoWellcome Inc.)
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06/2002 - 06/2003 Glaxo Smith Kline, Randomized, Double-Blind, 12-Week Trial Evaluating the Safety of the Fluticasone Propionate/Salmeterol DISKUS Combination Product 100/50 mcg BID Versus Fluticasone Propionate DISKUS 100 mcg BID in Symptomatic Pediatric Subjects (4-11years) with asthma. |
06/2002 - 06/2003 Novartis, A Randomized, Multicenter, Placebo-Controlled Parallel Group Study of Four Months Duration Per Patient To Evaluate the Safety and Efficacy of Treatment with 24g BID and 12g BID Formoterol, with Additional on-demand Formoterol Doses, Open in Adolescent and Adult Patients with Persistent Stable Asthma. |
09/2002 - 08/2003 Genentech, Open-Label Extension Study II of Xolair(Omalizumab) in Moderate to Severe, Persistent Asthma Subjects Who Completed Study Q2143g (ALTO)
|
10/2002 - 09/2003 AstraZeneca, A Six-Month, Randomized, Open-Label Safety Study of Symbicort™ (160/4.5mcg) Compared to Pulmicort Turbuhaler® in Asthmatic Children Aged Six to Eleven Years – Sapling |
10/2002 - 09/2003 AstraZeneca, A Twelve-Week, Randomized, Double-Blind, Double-Dummy Trial of Symbicort™ (40/4.5) versus its Mono-Products (budesonide and formoterol) in Asthmatic Children Aged Six to Fifteen Years – SEEDLING 40/4.5 |
02/2003 - 01/2004 Altana, 12 Weeks Treatment with 125g Roflumilast Versus 250g Roflumilast Versus Placebo in Patients with Asthma Protocol No. BY217/FK1 021.
|
06/2003 - 05/2004 Astra Zeneca, A Randomized, Partly Blinded, Multicenter, Parallel Study Comparing the Efficacy and Safety of PULMICORT RESPULES (budesonide inhalation suspension) at 0.5 mg QD, 1.0 mg QD, 1.0 mg BID, 2.0mg BID and PULMICORT TURBUHALER (budesonide) at 400 mcg BID in Adolescents (12 Years of Age and Older) and Adults with Moderate to Severe Asthma Protocol SD-004-0764. |
03/2004 - 02/2005 Novartis, CIGE025AIA05 A 1 Year, Randomized, Double Blind, Parallel-Group, Placebo-Controlled, Multicenter Evaluation of Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Omalizumab in Children (6 - <12 years) With Moderate-Severe, Persistent, Inadequately Controlled Allergic Asthma. |
07/2004 - 06/2005 Protocol Q2948g An Epidemiologic Study of Xolair® (Omalizumab): Evaluating Clinical Effectiveness and Long-Term Safety in Patients With Moderate to Severe Asthma (EXCELS) |
08/2004 - 07/2005 Protocol No. QAB149A2216 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-center, Multiple Dose (7 days) Dose-Ranging Study, to assess the Efficacy and Safety of 4 Doses of QAB149 (50, 100, 200 & 400 µg) Delivered Via the MDDPI and 1 Dose of QAB149 (400 µg) Delivered Via a SDDPI in Adult and Adolescent Patients (12 -75 years) With Stable Persistent Asthma. |
03/2005 - 08/2005 Pathogenesis of Immunological Diseases/Studies in Immune Regulation |
06/2005 - 05/2006 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-center, Multiple Dose (7 days) Dose-Ranging Study, to Assess the Efficacy and Safety of 4 Doses of QAB149 (50, 100, 200 & 400 µg) Delivered Via the MDDPI and 1 Dose of QAB149 (400µg) Delivered Via a SDDPI in Adult and Adolescent Patients (12 - 75 years) With Stable Persistent Asthma |
09/2005 - 08/2006 A Randomized, Parallel Group, Double-Blind, Comparative Trial Assessing Lung function and Other Measures of Asthma Control in Adults and Adolescents, at least 12 Years of Age, with Persistent Asthma, Who Have Either a B16-Arg/Arg, a B16-Gly/Gly or a B-16 Arg/Gly Genotype and are Treated With Fluticasone Propionate/Salmeterol DISKUS Combination Product 100/50mcg or Salmeterol DISKUS 50 mcg BIDSeptember, 2005Pathogenesis of Immunological Diseases/Studies in Immune Regulation |
10/2005 - 01/2006 SFA100314 A Stratified, Multicenter, Randomized, Double-Blind, Parallel Group, 4-Week Comparison of Fluticasone Propionate/Salmeterol DISKUS Combination Product 100/50mcg BID versus Fluticasone Propionate DISKUS 100mcg BID in Pediatric and Adolescent Subjects with Activity Induced Bronchospasm December, 2005 Severity Assessment and Treatment of Asthma |
08/2006 - 12/2006 A Phase IV Trial Evaluating Health Related Quality of Life and Serious Bacterial Infections in Subjects with Primary Immunodeficiency Disorder (PIDD) Treated with Subcutaneous Immune Globulin Following Conversion from Intravenous Globulin |
08/2006 - 12/2006 Determination of Minimum and Non-provoking Doses of Soy Protein in Soy Allergic Individuals |
08/2007 - 12/2007 GrassMATAMPL301: Efficacy and Safety/Tolerability of Grass MATA MPL, a Randomized, Placebo-Controlled, Double-Blind Study |
08/2007 - 12/2007 ProtocolQ3662g: A Phase IIIb Multicenter, Randomized, Double Blind, Placebo Controlled Study of Xolair in Subjects with Moderate to Severe Persistent Asthma Who are Inadequately Controlled With High-Dose Inhaled Corticosteroids and Long-Acting Beta-Agonist |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Zafra H, Zacharisen M.C. Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents, Volume 1, Number 2, 2002, pp. 143-156(14). doi.org/10.2174/1568014023355962 |
2. Healy, CT*, Zafra H and Zacharisen, M.C. What caused progressive wheezing and cough in this woman? Journal of Respiratory Diseases. 2003; 24(5):223-225. SCOPUS ID: 2-s2.0-0038242099 05/01/2003 |
3. Gimenez LM, Zafra H. Vocal cord dysfunction: an update. Ann Allergy Asthma Immunol. 2011 Apr;106(4):267-74; quiz 275. doi: 10.1016/j.anai.2010.09.004. PMID: 21457874. |
4. Bauer CS*, Chiu AM, Zafra HT, Gimenez LM, Nugent ML, Simpson PM, Vasudev M. The value of an allergy and clinical immunology rotation at an academic tertiary medical center. Ann Allergy Asthma Immunol. 2013 Jun;110(6):468-469.e9. doi: 10.1016/j.anai.2013.04.003. Epub 2013 Apr 30. PMID: 23706721. |
5. Sova C, Feuling MB, Baumler M, Gleason L, Tam JS*, Zafra H, Goday PS. Systematic review of nutrient intake and growth in children with multiple IgE-mediated food allergies. Nutr Clin Pract. 2013 Dec;28(6):669-75. doi: 10.1177/0884533613505870. Epub 2013 Oct 28. PMID: 24166727. |
6. Zafra H, Chiu A. The changing face of allergy/immunology fellowship programs. Ann Allergy Asthma Immunol. 2013 Nov;111(5):313-5. doi: 10.1016/j.anai.2013.09.006. PMID: 24125132. |
7. Sova C, Feuling MB, Baumler M, Gleason L, Tam JS*, Zafra H, Goday PS. Systematic review of nutrient intake and growth in children with multiple IgE-mediated food allergies. Nutr Clin Pract. 2013 Dec;28(6):669-75. doi: 10.1177/0884533613505870. Epub 2013 Oct 28. PMID: 24166727. |
8. Buelow BJ*, Lee C, Zafra HT, Dasgupta M, Hoffmann RG, Vasudev M. Egg baked in product open oral food challenges are safe in selected egg-allergic patients. Allergy Rhinol (Providence). 2014 Jul;5(2):110-2. doi: 10.2500/ar.2014.5.0092. Epub 2014 Jul 15. PMID: 25198996; PMCID: PMC4124576. |
9. Buelow BJ*, Kelly BT, Zafra HT, Kelly KJ. Absence of Peripheral Eosinophilia on Initial Clinical Presentation Does Not Rule Out the Diagnosis of Acute Eosinophilic Pneumonia. J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):597-8. doi: 10.1016/j.jaip.2015.01.008. Epub 2015 Feb 12. PMID: 25683924. |
10. Chen WL, Gallagher J*, Zafra H, Gedeit R. Hereditary angioedema presenting as compartment syndrome in a white girl. Ann Allergy Asthma Immunol. 2016 Sep;117(3):321-2. doi: 10.1016/j.anai.2016.06.021. Epub 2016 Jul 7. PMID: 27397069. |
11. FitzGerald JM1, Bleecker ER2, Nair P3, Korn S4, Ohta K5, Lommatzsch M6, Ferguson GT7, Busse WW8, Barker P9, Sproule S9, Gilmartin G10, Werkström V11, Aurivillius M11, Goldman M9; CALIMA study investigators*. Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2016 Oct 29;388(10056):2128-2141. doi: 10.1016/S0140-6736(16)31322-8. Epub 2016 Sep 5.
*Dr Zafra is one of the CALIMA study investigators
|
12. Chipps BE, Newbold P, Hirsch I, Trudo F, Goldman M.* Benralizumab efficacy by atopy status and serum immunoglobulin E for patients with severe, uncontrolled asthma.
Ann Allergy Asthma Immunol. 2018 May;120(5):504-511.e4. doi: 10.1016/j.anai.2018.01.030. Epub 2018 Feb 1. PMID: 29409951
*Dr Zafra is one of the CALIMA study investigators
|
13. DuBuske L, Newbold P, Wu Y, Trudo F.* Seasonal variability of exacerbations of severe, uncontrolled eosinophilic asthma and clinical benefits of benralizumab. Allergy Asthma Proc. 2018 Sep 4;39(5):345-349. doi: 10.2500/aap.2018.39.4162. Epub 2018 Aug 4.
*Dr Zafra is one of the CALIMA study investigators
|
14. Bleecker ER, Wechsler ME, FitzGerald JM, Menzies-Gow A, Wu Y, Hirsch I, Goldman M, Newbold P, Zangrilli JG.*Baseline patient factors impact on the clinical efficacy of benralizumab for severe asthma. Eur Respir J. 2018 Oct 18;52(4). pii: 1800936. doi: 10.1183/13993003.00936-2018. Print 2018 Oct.
*Dr Zafra is one of the CALIMA study investigators
|
15. Chupp G, Lugogo NL, Kline JN, Ferguson GT, Hirsch I, Goldman M, Zangrilli JG, Trudo F.* Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma. Ann Allergy Asthma Immunol. 2019 May;122(5):478-485. doi: 10.1016/j.anai.2019.02.016. Epub 2019 Feb 23.PMID: 3080250
*Dr Zafra is one of the CALIMA study investigators
|
16. Busse WW, Bleecker ER, FitzGerald JM, Ferguson GT, Barker P, Sproule S, Olsson RF, Martin UJ, Goldman M; BORA study investigators**. Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial. Lancet Respir Med. 2019 Jan;7(1):46-59. doi: 10.1016/S2213-2600(18)30406-5. Epub 2018 Nov 8. Erratum in: Lancet Respir Med. 2019 Jan;7(1):e1.PMID: 30416083
**Dr Zafra is one of the BORA study investigators
|
17. Banerji A, Riedl MA, Bernstein JA, Cicardi M, Longhurst HJ, Zuraw BL, Busse PJ, Anderson J, Magerl M, Martinez-Saguer I, Davis-Lorton M, Zanichelli A, Li HH, Craig T, Jacobs J, Johnston DT, Shapiro R, Yang WH, Lumry WR, Manning ME, Schwartz LB, Shennak M, Soteres D, Zaragoza-Urdaz RH, Gierer S, Smith AM, Tachdjian R, Wedner HJ, Hebert J, Rehman SM, Staubach P, Schranz J, Baptista J, Nothaft W, Maurer M; HELP Investigators***. Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks: A Randomized Clinical Trial. JAMA. 2018 Nov 27;320(20):2108-2121. doi: 10.1001/jama.2018.16773. Erratum in: JAMA. 2019 Apr 23;321(16):1636. PMID: 30480729
***Dr Zafra is one of the HELP study investigators
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18. Riedl MA, Bernstein JA, Craig T, Banerji A, Magerl M, Cicardi M, Longhurst HJ, Shennak MM, Yang WH, Schranz J, Baptista J, Busse PJ. An open-label study to evaluate the long-term safety and efficacy of lanadelumab for prevention of attacks in hereditary angioedema: design of the HELP*** study extension. Clin Transl Allergy. 2017 Oct 6;7:36. doi: 10.1186/s13601-017-0172-9. eCollection 2017.
***Dr Zafra is one of the HELP study investigators
|
19. Riedl MA, Maurer M, Bernstein JA, Banerji A, Longhurst HJ, Li HH, Lu P, Hao J, Juethner S, Lumry WR, Hébert J, Ritchie B, Sussman G, Yang WH, Escuriola Ettingshausen C, Magerl M, Martinez-Saguer I, Maurer M, Staubach P, Zimmer S, Cicardi M, Perego F, Wu MA, Zanichelli A, Al-Ghazawi A, Shennak M, Zaragoza-Urdaz RH, Ghurye R, Longhurst HJ, Zinser E, Anderson J, Banerji A, Baptist AP, Bernstein JA, Boggs PB, Busse PJ, Christiansen S, Craig T, Davis-Lorton M, Gierer S, Gower RG, Harris D, Hong DI, Jacobs J, Johnston DT, Levitch ES, Li HH, Lockey RF, Lugar P, Lumry WR, Manning ME, McNeil DL, Melamed I, Mostofi T, Nickel T, Otto WR, Petrov AA, Poarch K, Radojicic C, Rehman SM, Riedl MA, Schwartz LB, Shapiro R, Sher E, Smith AM, Smith TD, Soteres D, Tachdjian R, Wedner HJ, Weinstein ME, Zafra H, Zuraw BL. Lanadelumab demonstrates rapid and sustained prevention of hereditary angioedema attacks. Allergy: European Journal of Allergy and Clinical Immunology 2020 PMID: 32452549 SCOPUS ID: 2-s2.0-85087498118 01/01/2020
***Dr Zafra is one of the HELP study investigators
|
20. Lumry WR, Weller K, Magerl M, Banerji A, Longhurst HJ, Riedl MA, Lewis HB, Lu P, Devercelli G, Jain G, Maurer M; HELPStudy Investigators***. Impact of lanadelumab on health-related quality of life in patients with hereditary angioedema in the HELP study. Allergy. 2020 Nov 30. doi: 10.1111/all.14680. Epub ahead of print. PMID: 33258114.
***Dr Zafra is one of the HELP study investigators
|
21. Harrison TW, Chanez P, Menzella F, Canonica GW, Louis R, Cosio BG, Lugogo NL, Mohan A, Burden A, McDermott L, Garcia Gil E, Zangrilli JG; ANDHI study investigators****. Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial. Lancet Respir Med. 2021 Mar;9(3):260-274. doi: 10.1016/S2213-2600(20)30414-8. Epub 2020 Dec 22. Erratum in: Lancet Respir Med. 2021 Jan 25; PMID: 33357499.
****Dr Zafra is one of the ANDHI study investigators
|
22. Healy CT, Zafra H, Zacharisen MC, Chiles , Primack . What caused progressive wheezing and cough in this woman? Journal of Respiratory Diseases. 1 May 2003;24(5):223-225. |
23. Gimenez LM, Zafra H. Vocal cord dysfunction: an update. Ann Allergy Asthma Immunol. 2011 Apr;106(4):267-74; quiz 275. |
24. Bauer CS, Chiu AM, Zafra HT, Gimenez LM, Nugent ML, Simpson PM, Vasudev M. The value of an allergy and clinical immunology rotation at an academic tertiary medical center. Ann Allergy Asthma Immunol. 2013 Jun;110(6):468-469.e9. |
25. Zafra H, Chiu A. The changing face of allergy/immunology fellowship programs. Ann Allergy Asthma Immunol. 2013 Nov;111(5):313-5. |
26. Sova C, Feuling MB, Baumler M, Gleason L, Tam JS, Zafra H, Goday PS. Systematic review of nutrient intake and growth in children with multiple IgE-mediated food allergies. Nutr Clin Pract. 2013 Dec;28(6):669-75. |
27. Buelow BJ, Lee C, Zafra HT, Dasgupta M, Hoffmann RG, Vasudev M. Egg baked in product open oral food challenges are safe in selected egg-allergic patients. Allergy Rhinol (Providence). 2014 Jul;5(2):110-2. PMCID: PMC4124576 |
28. Walia CLS, Feuling MB, Baumler M, Gleason L, Tam JS, Zafra H, Goday PS. Changes in Calcium Intake and Growth in Children With Multiple Food Allergies Infant, Child, and Adolescent Nutrition. 2 December 2014;6(6):357-362. |
29. Buelow BJ, Kelly BT, Zafra HT, Kelly KJ. Absence of Peripheral Eosinophilia on Initial Clinical Presentation Does Not Rule Out the Diagnosis of Acute Eosinophilic Pneumonia. J Allergy Clin Immunol Pract. 2015;3(4):597-8. |
30. Chen WL, Gallagher J, Zafra H, Gedeit R. Hereditary angioedema presenting as compartment syndrome in a white girl. Ann Allergy Asthma Immunol. 2016 Sep;117(3):321-2. |
31. Busse WW, Bleecker ER, FitzGerald JM, Ferguson GT, Barker P, Sproule S, Olsson RF, Martin UJ, Goldman M, BORA study investigators. Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial. Lancet Respir Med. 2019 Jan;7(1):46-59. |
32. Riedl MA, Maurer M, Bernstein JA, Banerji A, Longhurst HJ, Li HH, Lu P, Hao J, Juethner S, Lumry WR, HELP Investigators. Lanadelumab demonstrates rapid and sustained prevention of hereditary angioedema attacks. Allergy. 2020 Nov;75(11):2879-2887. PMCID: PMC7689768 |
33. Lumry WR, Weller K, Magerl M, Banerji A, Longhurst HJ, Riedl MA, Lewis HB, Lu P, Devercelli G, Jain G, Maurer M, HELP Study Investigators. Impact of lanadelumab on health-related quality of life in patients with hereditary angioedema in the HELP study. Allergy. 2021 Apr;76(4):1188-1198. PMCID: PMC8247292 |
34. Harrison TW, Chanez P, Menzella F, Canonica GW, Louis R, Cosio BG, Lugogo NL, Mohan A, Burden A, McDermott L, Garcia Gil E, Zangrilli JG, ANDHI study investigators. Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial. Lancet Respir Med. 2021 Mar;9(3):260-274. |
35. Johnston DT, Busse PJ, Riedl MA, Maurer M, Anderson J, Nurse C, Inhaber N, Yu M, Banerji A, HELP Study Investigators. Effectiveness of lanadelumab for preventing hereditary angioedema attacks: Subgroup analyses from the HELP study. Clin Exp Allergy. 2021 Oct;51(10):1391-1395. PMCID: PMC9290609 |
36. Banerji A, Bernstein JA, Johnston DT, Lumry WR, Magerl M, Maurer M, Martinez-Saguer I, Zanichelli A, Hao J, Inhaber N, Yu M, Riedl MA, HELP OLE Investigators. Long-term prevention of hereditary angioedema attacks with lanadelumab: The HELP OLE Study. Allergy. 2022 Mar;77(3):979-990. PMCID: PMC9292251 |
37. Zafra H. Hereditary Angioedema: A Review. WMJ. 2022 Apr;121(1):48-53. |
38. Jones D, Zafra H, Anderson J. Managing Diagnosis, Treatment, and Burden of Disease in Hereditary Angioedema Patients with Normal C1-Esterase Inhibitor Journal of Asthma and Allergy. 2023;16:447-460. |
39. Louis R, Harrison TW, Chanez P, Menzella F, Philteos G, Cosio BG, Lugogo NL, de Luiz G, Burden A, Adlington T, Keeling N, Kwiatek J, Garcia Gil E, ANDHI Study Investigators. Severe Asthma Standard-of-Care Background Medication Reduction With Benralizumab: ANDHI in Practice Substudy. J Allergy Clin Immunol Pract. 2023 Jun;11(6):1759-1770.e7. |
40. Zafra H, Chiu AM. The changing face of the allergy/immunology fellowship, part 2: Death of the academic allergist? Ann Allergy Asthma Immunol. 2023 Sep;131(3):298-299. |
Abstracts |
1. Bauer C.S.*, Chiu A.M., Zafra H, Gimenez L.M., Nugent M.L., Simpson P.M., Vasudev M. The Value of an Allergy-Immunology Rotation in an Academic Tertiary Medical Center for Medical Student and Residents. Ann Allergy 2011;107: A110. |
2. Tallar M, Gimenez L, Zafra H, Chiu A. Systemic Reactions to Aeroallergen Immunotherapy: A Retrospective Review of Our Practice. Abstract only, Vol 137, issue 2, supplement, AB48, February 1, 2016. DOI: 10.1016/j.jaci.2015.12.157. |
3. Peloza D, Gimenez L, Crandall L, Nugent M, Simpson P, Zafra H. P127 The pediatric asthma adherence test: a survey for pediatric patient adherence to controller medications, Annals of Allergy, Asthma & Immunology,Volume 117, Issue 5, Supplement, 2016, Page S58, ISSN 1081-1206; https://doi.org/10.1016/j.anai.2016.09.137. |
4. Gobin, K*, Sheppard K, Chiu A, Zafra H. OR090 Quality improvement survey assessing immunotherapy efficacy and barriers in an outpatient setting, Annals of Allergy, Asthma & Immunology, Volume 119, Issue 5, Supplement, 2017, Page S13,ISSN 1081-1206,
https://doi.org/10.1016/j.anai.2017.08.065.
|
5. Sexton D, Brown N, Lumry W, Gower G, Hao J, Lu P, Zafra H. Lanadelumab And Cardiovascular Risk: Findings From The Phase 3 HELP Study. Abstract only, Vol 143, Issue 2, Supplement, AB45, Feb 01, 2019. DOI:https://doi.org/10.1016/j.jaci.2018.12.138 |
Non-Peer Reviewed Educational Products |
1. ZAFRA, H.T., Gimenez, L., Zacharisen, M.. FAQ's on Latex -related occupational asthma. American Latex Allergy Association Website. http://www.latexallergyresources.org/related/OccupationalAsthma.cfm |
2. ZAFRA, H. Tips that may help asthma sufferers enjoy the outdoors during “pollen season.” Metroparent Magazine, April 2013. |
Database, Video, or Other Research/Clinical Contributions |
1. ZAFRA, H. “Allergies to Cold---Allergic Rhinitis and Cold Urticaria.” WTMJ-AM Radio Broadcast, December 5, 2013 |
2. ZAFRA, H. Seasonal allergies. WTMJ-TV (NBC 4) Live at Noon. March 16, 2017. |
3. ZAFRA, H. How to help fall/ winter allergies. WTMJ-TV (NBC 4) Live at Noon. Sept 19. 2019. |