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CURRICULUM VITAE

Iris S. Kassem MD, PhD
Associate Professor
Department of Ophthalmology and Visual Sciences
Division of Pediatric Ophthalmology

OFFICE ADDRESS:
Eye Institute
925 N 87 St
Milwaukee, WI 53226

EDUCATION:
08/1993 - 05/1997 BS, Cornell University, Ithaca, NY
08/1998 - 05/2006 MD, PhD, State University of New York at Stony Brook, Stony Brook, NY

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/01/2006 - 06/30/2007 Intern, Internal Medicine, State University of New York at Stony Brook, Health Science Center, T16, Room 020, Stony Brook, NY 11794-8160
07/01/2007 - 06/30/2010 Resident, Ophthalmology, North Shore - Long Island Jewish Health System, 600 Northern Boulevard, Suite 107, Great Neck, NY 11021
07/01/2009 - 06/30/2010 Chief Resident, Ophthalmology, North Shore - Long Island Jewish Health System, 600 Northern Boulevard, Suite 107, Great Neck, NY 11021
07/09/2010 - 07/08/2011 Fellow, Ophthalmology, Pediatric Ophthalmology and Strabismus, University of Illinois at Chicago, 1855 W Taylor Street, MC 648, Chicago, IL 60612

FACULTY APPOINTMENTS:
07/09/2011 - 06/30/2015 Assistant Professor, Ophthalmology, Pediatric Ophthalmology and Strabismus, University of Illinois at Chicago, 1855 W Taylor Street, MC 648, Chicago, IL 60612
07/01/2015 - Present Assistant Professor, Ophthalmology, secondary appointment in Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, 925 N 87th Street, Milwaukee, WI 53226

ADMINISTRATIVE APPOINTMENTS:
2011 - 2015 Admissions Committee Member, Medical Scientist Training Program, University of Illinois at Chicago, Chicago, IL 60612
2012 - 2015 Liason, Faculty Academic Advancement Committee, University of Illinois at Chicago, Chicago, IL 60612

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
07/01/2017 - Present Resident Research Director, Ophthalmology and Visual Sciences, Medical College of Wisconsin

HOSPITAL STAFF PRIVILEGES:
08/2015 - Present Ophthalmology, Froedtert Hospital, Milwaukee, WI
08/2015 - Present Ophthalmology, Pediatric Ophthalmology, Children's Hospital of Wisconsin, Milwaukee, WI
09/2015 - Present Waukesha Memorial Hospital, Waukesha, WI
12/2015 - Present St. Joseph’s Hospital, West Bend, WI
03/2016 - Present Columbia St. Mary Hospital, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
Ophthalmology
2014
2024
   
AWARDS AND HONORS:
06/2020 Ambulatory Patient Experience Recognition, Children's Hospital of Wisconsin
2020 - Present Regional Top Doctor, Castle Connolly
2020 - Present Outstanding Graduate School Educator Award, Medical College of Wisconsin

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2007 - Present American Academy of Ophthalmology
2009 - Present The Association for Research in Vision and Ophthalmology
2011 - Present American Association for Pediatric Ophthalmology and Strabismus
2016 - Present Women in Ophthalmology
2019 - Present Human Proteome Organization

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
01/17/2019 - Present Journal of Pediatric Ophthalmology & Strabismus
Journal Review
01/18/2017 - 01/16/2019 Journal of Pediatric Ophthalmology & Strabismus
Ad-Hoc Reviewer
11/21/2018 - Present Investigative Ophthalmology and Visual Science

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2011 - 2015 Legislative Committee, American Association for Pediatric Ophthalmology and Strabismus
2011 - 2014 Preschool Screening, American Association for Pediatric Ophthalmology and Strabismus
2015 - Present Research Committee, American Association for Pediatric Ophthalmology and Strabismus
2016 - Present Legislative Committee, American Association for Pediatric Ophthalmology and Strabismus
2018 - Present Ambassador, Loan Repayment Program, National Institutes of Health

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Diagnosis and Predictive Value of the Ocular Manifestations of Fabry Disease
Source:
NIH/NEI
Role:
PI
PI:
Iris Kassem
Dates:
05/01/2019 - 03/31/2024
Direct Funds:
$341,380 (per year)
  
Non-Peer Review
Title:
Cerebrotendinous Xanthomatosis (CTX) Prevalence Study
Source:
Retrophin
Role:
PI
PI:
Iris Kassem
Dates:
09/11/2016 - Present
  
Pending
Peer Review
Title:
Ophthalmic Microscope with Intraoperative Optical Coherence Tomography
Source:
NIH
Role:
PI
PI:
Kassem
Dates:
03/01/2021 - Present
Direct Funds:
$390,398
  
Prior
Peer Review
Title:
K12 UIC Independent Clinician Vision Scientist Development Program
Source:
NIH/NEI
Role:
Awardee
PI:
Dimitri Azar
Dates:
08/2011 - 08/2014
  
Title:
Pediatric Ophthalmology Career Starter Grant
Source:
Knights Templar Eye Foundation
Role:
Principal Investigator
PI:
Iris Kassem
Dates:
2012 - 2014
Direct Funds:
$60,000
  
Title:
K08 Mentored Clinical Scientist Development Award
Source:
NIH/NEI
Role:
Principal Investigator
PI:
Iris Kassem
Dates:
09/30/2014 - 06/30/2019
Direct Funds:
$187,967
  
Non-Peer Review
Title:
Children's Research Institute K Award Supplement
Source:
Children's Research Institute
Role:
Principal Investigator
PI:
Iris Kassem
Dates:
07/01/2015 - 11/30/2019
Direct Funds:
$41,000 (per year)
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Iris Kassem, Steroids and the eye: an ophthalmologist’s perspective, Northwestern Department of Allergy and Immunology Lecture Series, Chicago, Illinois, 07/2011
Yi Pang and Iris Kassem, Updates from the Pediatric Eye Disease Investigator Group (PEDIG), Illinois College of Optometry Updates in Eye Care, Chicago, Illinois, 10/27/2014
Ocular Findings in Fabry Disease: More than Just Cornea Verticillata, Eye Institute Grand Rounds, Milwaukee, WI, 12/04/2019
 
National
Iris Kassem, Juvenile rabbit animal model of lensectomy to evaluate therapeutic interventions for postoperative inflammation and fibrosis, Clinical and Experimental Ophthalmology Conference,, Baltimore, Maryland, 07/14/2014 - 07/16/2014
Tarcy-Hornoch K, Binenbaum G, El-Dairi MA, Felius J, Jin J, Kassem IS, Nallasamy S, Pineles SL, Wang J, The Tools of Data Analysis: Matching the Hammer to the Nail, American Association of Pediatric Ophthalmology and Strabismus Annual Meeting, New Orleans, Louisiana, 03/27/2015
Overcoming Adversity, Women in Ophthalmology, Williamsburg, Virginia, 08/12/2016
YO ARVO: Navigating a Career as a Clinician-Scientist, American Academy of Ophthalmology Annual Meeting, Chicago, Illinois, 10/16/2016
Gil Binenbaum, Brian P. Brooks, Steven E. Brooks, Alejandra de Alba Campomanes, Fatema Ghasia, Judith Gurland, Gena Heidary, Iris Kassem, Stacy Pineles, Bahram B. Rahmani, Michael Yang, Evaluating the evidence: AAPOS Research Committee Analyses of what's hot in pediatric ophthalmology, American Association for Pediatric Ophthalmology and Strabismus, Washington, DC, 03/20/2018
Findings in Persistent Retinopathy of Prematurity, ROP Hot Topics 2018, Chicago, Illinois, 11/01/2018
Gil Binenbaum, Alejandra de Alba Campomanes, Steven E. Brooks, Brian Forbes, Fatema Ghasia, Iris Kassem, Stacy Pineles, Evaluating the Evidence: AAPOS Research Committee In-depth Analyses of What's New in Pediatric Ophthalmology, American Association for Pediatric Ophthalmology and Strabismus, San Diego, California, 03/29/2019
Ocular and Neurological Complications of COVID-19 Infection, Abbvie, 12/07/2020
 
International
Iris Kassem, Ocular trauma and amblyopia management, Argentinian Center of Strabismus (CAE) and the Argentinian Society for Pediatric Ophthalmology (SAOI), Buenos Aires, Argentina, 10/29/2015
Iris Kassem, Pediatric Ocular Trauma, Pediatric Ophthalmology and Strabismus, Wankaner, India, 01/24/2016
 

COMMITTEE SERVICE:
Medical College of Wisconsin
08/29/2019 - Present Member, Research Oversight, Ophthalmology and Visual Sciences, Medical College of Wisconsin
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Resident and Fellow Education
07/2017 - Present Strabismus Wet Lab Teaching
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Graduate Students
PhD Students Advised
Jonathon Young, Medical College of Wisconsin, 07/15/2015 - 03/01/2021 hanisms and Treatments for Fibrin Formation and the Immune Response after Intraocular Surgery in a Rabbit Animal Model
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Graduate Students
PhD Committees
Farah J Shareef, University of Illinois at Chicago, 2013 - 05/2015 Light Attenuating Artificial Iris: Implantable and Contact Lens Designs
PhD Students Advised
Joseph D Bogaard, University of Illinois at Chicago, 2014 - 05/20/2015 Evaluation of Therapeutic Interventions for the Treatment of Eye Disorders
 
Clinical/Research Fellows
Katherine Hare, University of Illinois at Chicago, 07/2011 - 07/2012 Clinical Fellow, Pediatric Ophthalmology and Strabismus
Senem Salar, University of Illinois at Chicago, 07/2012 - 07/2013 Clinical Fellow, Pediatric Ophthalmology and Strabismus
Maya Bitar, University of Illinois at Chicago, 07/2013 - 07/2014 Clinical Fellow, Pediatric Ophthalmology and Strabismus
 

COMMUNITY SERVICE ACTIVITIES:
09/15/2016 AEVR Emerging Vision Scientists Day on Capitol Hill
 

GLOBAL HEALTH ACTIVITIES:
01/15/2016 - 01/26/2016 Wankaner, India Eye Mission Trip
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Wade PR, Chen J, Jaffe B, Kassem IS, Blakely RD, Gershon MD. Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract. J Neurosci. 1996 Apr 01;16(7):2352-64. PMCID: PMC3327288
2. Evinger C, Bao JB, Powers AS, Kassem IS, Schicatano EJ, Henriquez VM, Peshori KR. Dry eye, blinking, and blepharospasm. Mov Disord. 2002;17 Suppl 2:S75-8. PMCID: PMC3327285
3. Kassem IS, Evinger C. Asymmetry of blinking. Invest Ophthalmol Vis Sci. 2006 Jan;47(1):195-201. PMCID: PMC3327295
4. Kassem IS, Kodsi SR. Marcus Gunn jaw winking with trigemino-oculomotor synkinesis of the inferior division of the oculomotor nerve. J AAPOS. 2009 Jun;13(3):315-6.
5. Kassem IS, Rubin SE, Kodsi SR. Exotropia in children with high hyperopia. J AAPOS. 2012 Oct;16(5):437-40. PMCID: PMC3479442
6. Gremida A, Kassem I, Traish A. Anterior capsular rupture following blunt ocular injury. Digit J Ophthalmol. 2011;17(4):66-8. PMCID: PMC3516173
7. Prickett AL, Salar S, Chow CC, Traish AS, Leiderman YI, Chau FY, Kassem IS. Traumatic eye injuries from collapsible wire laundry hampers. Pediatrics. 2013 Aug;132(2):e522-5. PMCID: PMC3727671
8. Kassem IS, Miller MT, Archer SM. One Year of Pediatric Ophthalmology and Strabismus Research in Review. Asia Pac J Ophthalmol (Phila). 2013 Nov-Dec;2(6):388-400. PMCID: PMC6839686
9. Feinstein E, Traish AS, Aakalu V, Kassem IS. A Case Report of Ablepharon-Macrostomia Syndrome with Amniotic Membrane Grafting. Case Rep Ophthalmol. 2015 Sep-Dec;6(3):366-72. PMCID: PMC4649710
10. Shareef FJ, Sun S, Kotecha M, Kassem I, Azar D, Cho M. Engineering a Light-Attenuating Artificial Iris. Invest Ophthalmol Vis Sci. 2016 Apr 01;57(4):2195-202. PMCID: PMC4849870
11. Kinori M, Wehrli S, Kassem IS, Azar NF, Maumenee IH, Mets MB. Biometry Characteristics in Adults and Children With Marfan Syndrome: From the Marfan Eye Consortium of Chicago. Am J Ophthalmol. 2017 May;177:144-149. PMCID: PMC5648325
12. Warren CC, Young JB, Goldberg MR, Connor TB, Kassem IS, Costakos DM. Findings in Persistent Retinopathy of Prematurity. Ophthalmic Surg Lasers Imaging Retina. 2018 07 01;49(7):497-503. PMCID: PMC6196355
13. Yu FPS, Sajdak BS, Sikora J, Salmon AE, Nagree MS, Gurka J, Kassem IS, Lipinski DM, Carroll J, Medin JA. Acid Ceramidase Deficiency in Mice Leads to Severe Ocular Pathology and Visual Impairment. Am J Pathol. 2019 02;189(2):320-338. PMCID: PMC6412726
14. Bogaard JD, Young JB, Movahedan A, Kassem IS. Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy. Transl Vis Sci Technol. 2019 Jan;8(1):5. PMCID: PMC6327344
15. Han DP, Skumatz C, Besharse JC, Kassem IS. Sustained Anti-Vascular Endothelial Growth Factor Activity of Aflibercept (Eylea) After Storage in Polycarbonate Syringes Used for Intravitreal Injection: A Pathway to Safety and Efficiency. J Ocul Pharmacol Ther. 2019 06;35(5):278-282. PMCID: PMC6588124
16. Dikopf MS, Machen LA, Hallak JA, Chau FY, Kassem IS. Zone of retinal vascularization and refractive error in premature eyes with and without spontaneously regressed retinopathy of prematurity. J AAPOS. 2019 08;23(4):211.e1-211.e6. PMCID: PMC6778011
17. Miller JJ, Aoki K, Reid CA, Tiemeyer M, Dahms NM, Kassem IS. Rats deficient in α-galactosidase A develop ocular manifestations of Fabry disease. Sci Rep. 2019 06 28;9(1):9392. PMCID: PMC6599056
18. Dotan G, Kassem I, Weaver D, Wagner RS. Managing a Slipped Muscle Following an Adjustable Suture Medial Rectus Recession. J Pediatr Ophthalmol Strabismus. 2019 07 01;56(4):209-211.
19. Evinger C, Kassem IS. Animal models of benign essential blepharospasm and hemifacial spasm Movement Disorders. 2005:253-263.
20. Young JB, Keppel TR, Waas M, Salmon AE, Buchberger AR, Skumatz CMB, Gundry RL, Kassem IS. Quantitative proteomic analysis of aqueous humor after rabbit lensectomy reveals differences in coagulation and immunomodulatory proteins. Mol Omics. 2020 04 01;16(2):126-137.
21. Young JB, Buchberger AR, Bogaard JD, Runquist M, Skumatz CMB, Kassem IS Tissue plasminogen activator effects on fibrin volume and the ocular proteome in a juvenile rabbit model of lensectomy. Transl Vis Sci Technol. (under revision)
22. Low SWY, Connor TB, Kassem IS, Costakos DM, Chaurasia SS. Small leucine-rich proteoglycans (Slrps) in the retina International Journal of Molecular Sciences. 2 July 2021;22(14).
 
Books, Chapters, and Reviews
1. Kassem IS (2015) Amblyopia. MedLink Neurology (Goodwin J Ed) San Diego: MedLink Corporation. Available at www.medlink.com.
2. Evinger C, Kassem IS (2005) Animal models of benign essential blepharospasm and hemifacial spasm. Animal Models of Movement Disorders (M LeDoux, Ed) Academic Press/Elsevier.
 
Editorials, Letters to Editor, Other
1. Dotan G, Kassem I, Weaver D. Managing a slipped muscle following an adjustable suture medial rectus recession. Journal of Pediatric Ophthalmology & Strabismus 2019;56(4):209-211.
 
Abstracts
1. Kassem IS, Evinger LC. Do humans exhibit eyelid dominance? Program No. 71.30. Society for Neuroscience General Meeting, San Diego, CA (2001).
2. Kassem IS, Evinger C. Effects of chronic facial nerve stimulation on the development of hemifacial spasm. Program No. 463.1. Society for Neuroscience General Meeting, Orlando, FL (2002).
3. Evinger C, Kassem IS. Origin of blink oscillations. Program No. 391.5. Society for Neuroscience General Meeting, New Orleans, LA (2003).
4. Kassem IS, Evinger C. Chronic facial nerve stimulation modifies the reflex blink. Program No. 391.4. Society for Neuroscience General Meeting, New Orleans, LA (2003).
5. Evinger C, Kassem IS, Ronneburger A, Dauvergne C. Rearranging the face – reorganizing trigeminal control of reflex blinks. Program No. 881.1. Society for Neuroscience General Meeting, San Diego, CA (2004).
6. Kassem IS, Evinger C, Pomeranz H. Dry eye, blinking, and hemifacial spasm. Program No 4037. ARVO Annual Meeting, Ft Lauderdale, FL. (2009).
7. Kassem IS, Rubin SR, Kodsi SR. Exotropia in children with high hyperopia. Program No. 14. AAPOS Annual Meeting, Seattle, WA. (2010).
8. Wehrli S, Mets M, Kassem IS, Fawzi AA, Azar NF, Maumenee IH. Biometric characteristics of the Marfan eye. Program No 5709. ARVO Annual Meeting, Ft Lauderdale, FL. (2013).
9. Movahedan A, Kassem IS, Traish AS. Effect of intraocular enoxaparin on postoperative fibrosis in a juvenile rabbit model of lensectomy. ASCRS Annual Meeting, Boston, MA. (2014) - Award: "Poster of Interest"
10. Wubben TJ, Khan A, Yasar K, Leiderman YI, Chau FY, Royston TJ, Kassem IS Ocular injuries from the impact of collapsible laundry hamper wires. Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5486.
11. Kassem IS, Oltra EZ, Salar S. Visual outcomes in pediatric open globe trauma with early amblyopia therapy. Invest. Ophthalmol. Vis. Sci. 2014; 55(13):804.
12. Shareef F, Szlachta D , Contreras G, Chen A, Kassem IS, Azar DT, Cho M Designing a Photo-Responsive Contact Lens. Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):6102. Award: MIT Outstanding Poster
13. Bogaard JD, Kassem IS. Evaluation of therapeutic interventions for postoperative inflammation and fibrosis in a juvenile rabbit model of lensectomy. Invest. Ophthalmol. Vis. Sci.. 2015; 56(7):3217. Hot Topic Presentation
14. Dikopf M, Kassem IS, Chau FY. Vascularization patterns and refractive error in retinopathy of prematurity. Invest. Ophthalmol. Vis. Sci.. 2015; 56(7):966.
15. Bogaard JD, Young J, Kassem IS. Tissue Plasminogen Activator for the Treatment of Fibrin After Lensectomy with Intraocular Lens Insertion in a Juvenile Rabbit Model. Invest. Ophthalmol. Vis. Sci. 2016.
16. Young JB, Conklyn D, Bogaard JD, Whiteley H, Kassem IS. Inhibition of Fibrin and Inflammation with Enoxaparin and Triamcinolone in a Juvenile Rabbit Model of Lensectomy. Invest. Ophthalmol. Vis. Sci. 2016.
17. Kassem IS, Miller JJ, Aoki K, Murphy CA, Young J, Tiemeyer M, Dahms NM. Early ocular manifestations of Fabry disease in alpha-galactosidase A-deficient rats. ARVO Annual Meeting, Baltimore, MD (2017).
18. Vogel R, Kassem IS, Han DP, Costakos D. Conjunctival bacterial flora and antiseptic effect of povidone-iodine for infants in the intensive care unit screened for retinopathy of prematurity. ARVO Annual Meeting, Baltimore, MD (2017).
19. Young J, Jin S, Skumatz C, Kassem IS. Aqueous humor protein changes after rabbit lensectomy with intraocular lens insertion. ARVO Annual Meeting, Baltimore, MD (2017).
20. Jhaj G, Costakos DM, Laurenti K, Kassem IS. Clinical Course and Treatment Rates of Retinopathy of Prematurity in Extremely Premature Infants. AAPOS Annual Meeting, Washington, DC. (2018).
21. Young JB, Bogaard J, Arpinar VE, Skumatz C, Runquist M, Nencka A, &Kassem IS. Magnetic Resonance Imaging(MRI)ofanterior chamberfibrosis to evaluate therapeutic interventions after lensectomy with intraocular lens(IOL)insertion in a rabbit animal model. Imaging in the Eye. Honolulu, HI (2018).
22. Han D, Skumatz C, Besharse J, Kassem I. Sustained anti-VEGF activity of aflibercept (EyleaTM) after storage in polycarbonate syringes used for intravitreal injection: a pathway to safety and efficiency in high volume clinics providing intravitreal therapy. ARVO Annual Meeting, Honolulu, HI (2018) Hot Topic Presentation.
23. Young J. Keppel T, Skumatz C, Gundry R, Kassem I. Aqueous humor protein changes in response to the different portions of lensectomy with intraocular lens (IOL) implantation in the juvenile rabbit. ARVO Annual Meeting, Honolulu, HI (2018).
24. Kassem I, Miller J, Reid C, Dahms N. Ocular Vascular Manifestations of Fabry Disease in alpha-galactosidase A-deficient Rats. ARVO Annual Meeting, Honolulu, HI (2018).
25. Young, Bakhshinejad A, Skumatz C, Runquist M, Kassem IS. Quantification of fibrin volume in a juvenile rabbit model of lensectomy using 9.4 Tesla magnetic resonance imaging. ARVO Annual Meeting, Vancouver, BC (2019).
26. Desai S, Vogel R. Kassem IS, Costakos DM. Conjunctival Ocular Flora Before and After Povidone Iodine in Neonates. AAPOS Annual Meeting, San Diego, CA. (2019).