Medical College of Wisconsin
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CURRICULUM VITAE

James A. Hokanson PhD
Assistant Professor
Department of Biomedical Engineering

OFFICE ADDRESS:
8701 Watertown Plank Road
Milwaukee, WI 53226

EDUCATION:
08/2002 - 05/2006 BS Biomedical Engineering, Washington University in St. Louis, St. Louis, MO
08/2002 - 05/2006 BS Electrical Engineering, Washington University in St. Louis, St. Louis, MO
08/2006 - 02/2014 PhD Bioengineering, University of Pittsburgh, Pittsburgh, PA

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
03/2014 - 07/2019 Postdoctoral Associate, Biomedical Engineering, Duke University, Durham, NC
07/2019 - 12/2020 Research Scientist, Biomedical Engineering, Duke University, Durham, NC

FACULTY APPOINTMENTS:
01/2021 - Present Assistant Professor, Joint Department of Biomedical Engineering, Medical College of Wisconsin, Biomedical Engineering, TBRC, 8701 Watertown Plank Road, Milwaukee, WI 53226

CENTER/INSTITUTE AFFILIATIONS:
06/2023 - Present Member, Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI

AWARDS AND HONORS:
04/2006 Rick Grodsky Award for Technical Achievement, Wash U. Engineering
05/2009 TA of the Year, U. Pitt Bioengineering
05/2009 Poster Abstract Honorable Mention, UPMC Rehabilitation Institute Research Day
09/2009 - 08/2010 Multi-modal Neuroimaging Trainee (T90), NIH NIDA
06/2010 Student Travel Award, Neural Interfaces Conference
06/2010 Student Travel Award, Beyond Brain Machine Interface Workshop
09/2010 - 08/2012 Integrative Graduate Education and Research Traineeship (IGERT), NSF
12/2019 Best Poster Award, NIDDK CAIRIBU meeting
12/2020 Best Poster Award, NIDDK CAIRIBU meeting

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2003 - 2018 Institute of Electrical and Electronics Engineers (Member)
2006 - 2013 Center for the Neural Basis of Cognition (Member)
2006 - 2014 American Society for Engineering Education (Member)
2007 - Present Society for Neuroscience (Member)
2016 - Present International Continence Society (Member)
2017 - Present American Urological Association (Member)
2020 - Present Society for Basic Urological Research (Member)
2021 - Present American Urogynecologic Society (Member)
2022 - Present Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction (Member)
2023 - 2024 International Consultation on Incontinence – Research Society (Member)
2023 - Present SUFU Research Network (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
03/2019 - Present American Journal of Physiology – Renal Physiology
01/2023 - Present Neurourology and Urodynamics
Journal Review
09/2011 - Present Journal of Neural Engineering
11/2016 - Present Journal of Neurotrauma
05/2017 - Present American Journal of Physiology-Renal Physiology
07/2017 - Present American Journal of Obstetrics & Gynecology
07/2017 - Present Neuromodulation: Technology at the Neural Interface
01/2018 - Present Scientific Reports
11/2019 - Present IEEE Transactions on Neural Systems and Rehabilitation Engineering
01/2021 - Present American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
10/2021 - Present Biochemical Pharmacology
11/2021 - Present Frontiers in Neuroscience
02/2022 - Present Neurourology and Urodynamics
06/2024 - Present Frontiers in Physiology
09/2024 - Present IEEE Transactions on Biomedical Circuits and Systems
09/2024 - Present Journal of Urology
09/2024 - Present Current Opinion in Biomedical Engineering
03/2026 - Present npj Regenerative Medicine
05/2026 - Present Techniques in Coloproctology

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
09/2024 reviewer, pilot awards, AHW

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
04/2021 ad hoc reviewer, R25 and F31 reviews, NIH NIDDK
04/2022 - 03/2025 Member, ISAC reviews, NIH NIDDK
02/2023 reviewer, Swiss National Science Foundation
02/2023 ad hoc reviewer, F grants, NIH NIDDK
09/2023 reviewer, research scholar awards, American Urological Association
02/2024 - Present Member, Basic Science Committee, SUFU
07/2025 reviewer, Swiss National Science Foundation
11/2025 ad hoc reviewer, SBIR/STTR, NIH ZRG1 KUDS-R11
02/2026 - Present Secretary, Research Network, SUFU
05/2026 ad hoc reviewer, R18, R61/R33, UG3/UH3, NIH ZRG1 NV-J (52)
07/01/2026 - 06/30/2030 standing member, Kidney and Urological Systems Function and Dysfunction Study Section (KUFD), NIH NIDDK

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Advancing the Measurement and Classification of Lower Urinary Tract Dysfunction
Source:
NIDDK, U01DK097780
Role & Effort:
Co-Investigator
PI:
Cindy Amundsen, Kevin Weinfurt
Dates:
09/2019 - 08/2026
Direct Funds:
$2,474,900
  
Title:
Urothelial Cells and Sensory Signaling
Source:
NIDDK, R01DK140233
Role & Effort:
Co-Investigator
PI:
Aaron Mickle
Dates:
09/2024 - 08/2029
Direct Funds:
$1,836,660
  
Title:
University of Washington LURN II Research Site
Source:
NIDDK, U01DK100011
Role & Effort:
Co-Investigator, Principal Investigator on MCW subcontract
PI:
Claire Yang
Dates:
09/2024 - 08/2026
Direct Funds:
$48,962
  
Title:
Chronic tibial neuromodulation model development
Source:
Advancing a Healthier Wisconsin Endowment Pilot Grant
Role & Effort:
Principal Investigator
PI:
Hokanson
Dates:
01/2025 - 12/2025
Direct Funds:
$50,000
  
Title:
Impact of tibial nerve stimulation approach on nerve recruitment and bladder outcomes
Source:
SUFU Medtronic Grant
Role & Effort:
Principal Investigator
PI:
Hokanson
Dates:
03/2025 - 09/2026
Direct Funds:
$25,000
  
Title:
Animal model and resource development for preclinical lower urinary tract research
Source:
NIDDK, R21DK140694
Role & Effort:
Principal Investigator
PI:
Hokanson
Dates:
08/2025 - 07/2027
Direct Funds:
$432,625
  
Title:
Developing SURN Registry for Implantable Tibial Neuromodulation for Urgency Urinary Incontinence
Source:
SUFU Research Network
Role & Effort:
Mentor
PI:
Tope Rude
Dates:
01/2026 - 12/2027
Direct Funds:
$50,000
  
Title:
Optimization of Chronic Neuromodulation in Treating Neurogenic Bladder Dysfunction
Source:
NIDDK, R01DK147123
Role & Effort:
Principal Investigator
PI:
Hokanson
Dates:
04/21/2026 - 02/28/2031
Direct Funds:
$2,730,816
  
Prior
Peer Review
Title:
Electrical stimulation of the urethra to prevent urgency urinary incontinence episodes
Source:
Urology Care Foundation Research Scholar Award
Role & Effort:
Research Scholar
Dates:
07/2017 - 06/2019
Direct Funds:
$80,000
  
Title:
Predicting Urinary Continence Status with Sacral Neuromodulation and Botulinum Toxin Treatments
Source:
NIDDK, K01DK121866
Role & Effort:
Principal Investigator
PI:
Hokanson
Dates:
09/2020 - 08/2024
Direct Funds:
$363,416
  
Title:
Changes in brain and brainstem fMRI activity during bladder filling with and without tibial nerve stimulation
Source:
MCW Research Affairs Committee pilot grant
Role & Effort:
Principal Investigator
PI:
Hokanson
Dates:
07/2023 - 12/2024
Direct Funds:
$35,000
  
Title:
Neuroanatomical basis for tibial neuromodulation
Source:
NIDDK CAIRIBU Collaboration Grant
Role & Effort:
Co-Principal Investigator
PI:
Hokanson, Satkunendrarajah
Dates:
09/2024 - 08/2025
Direct Funds:
$50,000
  
Non-Peer Review
Title:
Peripheral Nerve Stimulation to Treat Overactive Bladder Symptoms
Source:
NIDDK, K12DK100024
Role & Effort:
Research Scholar
PI:
Cindy Amundsen
Dates:
08/2014 - 06/2017
Direct Funds:
$328,424
  
Title:
Improved phenotyping of lower urinary tract function; towards personalized medicine
Source:
Advancing a Healthier Wisconsin Research and Education Program
Role & Effort:
Principal Investigator
PI:
Hokanson
Dates:
02/2021 - 09/2023
Direct Funds:
$413,000
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
International
Hokanson, Beyond Averages. Using Prediction Modeling to Improve Therapy Selection and Design, AUGS-IUGA joint meeting, Austin, Texas, 06/14/2022 - 06/18/2022
Hokanson, State-Dependent Bioelectronics Interface to Control Bladder Function, INS 2024, Vancouver, Canada, 05/11/2024 - 05/16/2024
 
National
Hokanson, Beyond sacral root modulation: Pudendal nerve stimulation to improve bladder function, Society for Neuroscience Annual Meeting, San Diego, California, 11/12/2016 - 11/16/2016
Hokanson, Making Physiology Matter, NIDDK Female Urethral Function and Failure Workshop, Online, 09/30/2020
Overcoming Challenges in the Research World, CAIRIBU trainee event, Virtual, 12/02/2021
Hokanson, Neural Control of Vesicourethral Function, NIDDK Neurourology Meeting, Online, 08/22/2022 - 08/23/2022
Growing Your Career: How to move from point A to point B as an early career stage investigator, CAIRIBU trainee event, North Bethesda, MD, 11/30/2022
Hokanson, Towards Physiology as an Important Tool for Personalized LUTS Therapies, SBUR at the AUA, Chicago, Illinois, 04/29/2023
Hokanson, Towards physiology as an important tool for personalized pelvic health therapies, KUMC OBGYN Grand Rounds, Kansas City, KS, 09/08/2023
Hokanson, Phenotyping, Prediction Modeling and the Path Forward to Individualized Treatments (with a focus on OAB/UUI), SUFU Winter Meeting, Fort Lauderdale, Florida, 02/20/2024 - 02/24/2024
Hokanson, Ippolito, Sheyn, Hendrickson, Rose, Practical and Ethical Considerations for AI in Urogynecology and Urology: A Panel Discussion, AUGS annual meeting, Washington, DC, 10/14/2024 - 10/17/2024
Hokanson, Prediction modeling applied to non-cancerous genitourinary conditions, Duke KURe meeting, Durham, NC, 04/09/2025
Hokanson, Yang, Measurement of lower urinary tract function, NIDDK Addressing Gaps, Challenges, and Opportunities Related to Data and Metadata Standards for NIDDK Research Priorities meeting, Online, 06/03/2025 - 06/04/2025
Hokanson, Sexual function in women with bothersome lower urinary tract symptoms: findings from the symptoms of lower urinary tract dysfunction research network (LURN) cohort study, NIDDK CAIRIBU Uro-Lit Live, Online, 10/29/2025
Hokanson, Insights into the pathophysiology of urgency urinary incontinence (UUI) from the LURN organ study, NIDDK CAIRIBU Meeting, Madison, WI, 12/2025
Hokanson, Improving tibial nerve stimulation and understanding the pathophysiology of UUI, Pelvic Floor Conference, Cleveland Clinic, 03/03/2026
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
International
James Hokanson, Spacing and Size of Electrocorticography electrodes with a focus on Brain Computer Interfaces, Neurohike Motor Control Conference, Kananaskis, Alberta, Canada, 09/22/2006 - 09/25/2006
James Hokanson, Channel Interactions During Synchronous Microstimulation with High Density Microelectrode Arrays, International Functional Electrical Stimulation Society, Banff, Alberta, Canada, 09/09/2012 - 09/12/2012
James Hokanson, State-Dependent Pudendal Nerve Stimulation to Increase Bladder Capacity and Voiding Efficiency in Cats, • International Continence Society Meeting, Philadelphia, Pennsylvania, 08/28/2018 - 08/31/2018
 
National
James Hokanson, Using Classifiers to Identify Differences in Evoked Responses from Stimulation of Primary Afferents, • Biomedical Engineering Society Conference, Pittsburgh, Pennsylvania, 10/07/2009 - 10/10/2009
James Hokanson, Effects of Spatial and Temporal Parameters of Primary Afferent Microstimulation on Neural Responses Evoked in Primary Somatosensory Cortex of an Anesthetized Cat, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Boston, Massachusetts, 08/30/2011 - 09/03/2011
James Hokanson, Predicting Urinary Continence Status with Sacral Neuromodulation and Botulinum Toxin Treatments, NIDDK CAIRIBU Meeting, Ellicott City, Maryland, 12/12/2018 - 12/14/2018
James Hokanson, Intravesical Prostaglandin E2: Bladder Irritant or Urethral Smooth Muscle Relaxer?, NIDDK CAIRIBU Meeting, Kansas City, Missouri, 12/04/2019 - 12/06/2019
Whitney K. Hendrickson, Development of models predicting treatment efficacy and need for self-catheterization after intradetrusor onabotulinumtoxina for non-neurogenic urgency incontinence in women, SUFU Meeting, Online, 02/25/2021 - 02/27/2021
Wei He, Impact of Bladder Filling Rate on Cystometric Variables in Anesthetized Rats, SUFU Meeting, Nashville, Tennessee, 03/07/2023 - 03/11/2023
Farshad Samadifam, Outcome prediction for sacral neuromodulation therapy in women with non-neurogenic urgency incontinence: a machine learning approach, SUFU Meeting, Fort Lauderdale, Florida, 02/20/2024 - 02/24/2024
 

COMMITTEE SERVICE:
Medical College of Wisconsin
01/2021 - 09/2023 Member, Undergraduate Committee, Joint Department of Biomedical Engineering, MCW
02/2021 - Present Faculty Advisor, SUPREMES, Joint Department of Biomedical Engineering, MCW
09/21/2022 poster judge, MCW Annual Postdoc Symposium, MCW
10/31/2022 faculty facilitator, RCR Refresher, MCW
05/08/2023 faculty facilitator, RCR Refresher, MCW
06/2023 - Present Assistant Representative, Faculty Council, MCW
10/30/2023 faculty facilitator, RCR Refresher, MCW
10/2023 - Present Member, Research Committee, Joint Department of Biomedical Engineering, MCW
09/15/2025 poster judge, MCW Annual Postdoc Symposium, MCW
09/17/2025 panelist, MCW Spotlight on Science Postdoc Seminar, MCW
09/2025 - Present Member, AI & Date Science Committee, Marquette Olin College of Engineering
 

MCW TEACHING ACTIVITIES:
Graduate Student Education
08/2021 - 05/2022 Faculty advisor for design team in course BIEN 4920: Principles of Design & BIEN 4998: Senior Design Project
08/2021 - 12/2021 Co-Instructor for informal MATLAB programming course for students in the department
10/2021 Faculty lecturer for BIEN 4931/5931: Tissue Engineering
12/2022 Faculty lecturer for BIEN 6200 Biomedical Signal Processing
08/2023 - 12/2023 Co-Instructor for BIEN 2100 Statistics for Biomedical Engineering
02/28/2024 faculty lecturer for BIEN 6960 Neuroimaging Journal Club
03/2024 Faculty lecturer for BIEN 4931/5931: Tissue Engineering
08/2024 - 05/2025 Faculty advisor for design team in course BIEN 4920: Principles of Design & BIEN 4998: Senior Design Project
08/2024 - 12/2024 Co-Instructor for BIEN 4391/5931 Scientific Computing for Engineers
08/2024 - 12/2024 Co-Instructor for BIEN 4391/5931 Scientific Computing for Engineers
11/2024 Faculty lecturer for BIEN 5600 Neural Engineering
01/2026 - 05/2026 Co-Instructor for BIEN 4391/5931 Scientific Computing for Engineers
 

EXTRAMURAL TEACHING:
Graduate Student Education
01/2003 - 05/2003 Washington University in St. Louis, Course Director for EN120 Freshman Engineering Seminar
01/2004 - 05/2004 Washington University in St. Louis, Course Director for EN120 Freshman Engineering Seminar
01/2005 - 05/2005 Washington University in St. Louis, Course Director for EN120 Freshman Engineering Seminar
08/2005 - 12/2005 Washington University in St. Louis, Teaching Assistant for Introduction to Electrical and Computer Engineering
08/2006 - 12/2006 Washington University in St. Louis, Teaching Assistant for Introduction to Electrical and Computer Engineering
01/2007 - 05/2007 University of Pittsburgh, Lab Instructor for BIOE 1150 Bioengineering Methods Lab
01/2008 - 05/2008 University of Pittsburgh, Lab Instructor for BIOE 1150 Bioengineering Methods Lab
01/2008 - 05/2008 University of Pittsburgh, Teaching Assistant for BIOE 1310 Bioinstrumentation
01/2009 - 05/2009 University of Pittsburgh, Teaching Assistant for BIOE 1310 Bioinstrumentation
01/2010 - 05/2010 University of Pittsburgh, Teaching Assistant for BIOE 1310 Bioinstrumentation
04/2026 University of Miami, Faculty lecturer for BME 615 Current Trends in Neural Engineering
 
Community/Lay Public
06/2005 Washington University in St. Louis, Introduction to HTML
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Gaunt RA, Hokanson JA, Weber DJ. Microstimulation of primary afferent neurons in the L7 dorsal root ganglia using multielectrode arrays in anesthetized cats: thresholds and recruitment properties. J Neural Eng. 2009 Oct;6(5):055009. PMCID: PMC2894985
2. Bourbeau DJ, Hokanson JA, Rubin JE, Weber DJ. A computational model for estimating recruitment of primary afferent fibers by intraneural stimulation in the dorsal root ganglia. J Neural Eng. 2011 Oct;8(5):056009. PMCID: PMC3178662
3. Weber DJ, London BM, Hokanson JA, Ayers CA, Gaunt RA, Torres RR, Zaaimi B, Miller LE. Limb-state information encoded by peripheral and central somatosensory neurons: implications for an afferent interface. IEEE Trans Neural Syst Rehabil Eng. 2011 Oct;19(5):501-13. PMCID: PMC3694199
4. Szigeti B, Gleeson P, Vella M, Khayrulin S, Palyanov A, Hokanson J, Currie M, Cantarelli M, Idili G, Larson S. OpenWorm: An open-science approach to modeling Caenorhabditis elegans Frontiers in Computational Neuroscience. 3 November 2014;8(November):1-7.
5. Langdale CL, Hokanson JA, Sridhar A, Grill WM. Stimulation of the pelvic nerve increases bladder capacity in the prostaglandin E<sub>2</sub> rat model of overactive bladder. Am J Physiol Renal Physiol. 2017 Sep 01;313(3):F657-F665. PMCID: PMC5625104
6. Hokanson JA, Langdale CL, Sridhar A, Grill WM. OAB without an overactive bladder in the acute prostaglandin E2 rat model. Am J Physiol Renal Physiol. 2017 Nov 01;313(5):F1169-F1177. PMCID: PMC5792156
7. Lubba C, Mitrani E, Hokanson J, Grill WM, Schultz SR. Real-time decoding of bladder pressure from pelvic nerve activity CP International IEEE EMBS Conference on Neural Engineering Ner. 10 August 2017:617-620.
8. Hokanson JA, Langdale CL, Sridhar A, Grill WM. Stimulation of the sensory pudendal nerve increases bladder capacity in the rat. Am J Physiol Renal Physiol. 2018 Apr 01;314(4):F543-F550. PMCID: PMC5966759
9. Rutter EM, Langdale CL, Hokanson JA, Hamilton F, Tran H, Grill WM, Flores KB. Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression. IEEE Trans Neural Syst Rehabil Eng. 2018 Aug;26(8):1636-1644. PMCID: PMC6531051
10. Hokanson JA, Gaunt RA, Weber DJ. Effects of Synchronous Electrode Pulses on Neural Recruitment During Multichannel Microstimulation. Sci Rep. 2018 Aug 30;8(1):13067. PMCID: PMC6117337
11. Javer A, Currie M, Lee CW, Hokanson J, Li K, Martineau CN, Yemini E, Grundy LJ, Li C, Ch'ng Q, Schafer WR, Nollen EAA, Kerr R, Brown AEX. An open-source platform for analyzing and sharing worm-behavior data. Nat Methods. 2018 Sep;15(9):645-646. PMCID: PMC6284784
12. Langdale CL, Hokanson JA, Milliken PH, Sridhar A, Grill WM. Stimulation of the pelvic nerve increases bladder capacity in the PGE<sub>2</sub> cat model of overactive bladder. Am J Physiol Renal Physiol. 2020 Jun 01;318(6):F1357-F1368. PMCID: PMC7717121
13. Hokanson JA, Langdale CL, Milliken PH, Sridhar A, Grill WM. Effects of intravesical prostaglandin E<sub>2</sub> on bladder function are preserved in capsaicin-desensitized rats. Am J Physiol Renal Physiol. 2021 Feb 01;320(2):F212-F223. PMCID: PMC7948121
14. Hokanson JA, Langdale CL, Sridhar A, Milliken P, Grill WM. State-dependent bioelectronic interface to control bladder function. Sci Rep. 2021 Jan 11;11(1):314. PMCID: PMC7801663
15. Brady SS, Bavendam TG, Bradway CK, Conroy B, Dowling-Castronovo A, Epperson CN, Hijaz AK, Hsi RS, Huss K, Kim M, Lazar J, Lee RK, Liu CK, Loizou CN, Miran S, Mody L, Norton JM, Reynolds WS, Sutcliffe S, Zhang N, Hokanson JA. Noncancerous Genitourinary Conditions as a Public Health Priority: Conceptualizing the Hidden Burden. Urology. 2022 Aug;166:39-49. PMCID: PMC8924010
16. Hobbs KT, Choe N, Aksenov LI, Reyes L, Aquino W, Routh JC, Hokanson JA. Machine Learning for Urodynamic Detection of Detrusor Overactivity. Urology. 2022 Jan;159:247-254. PMCID: PMC8865755
17. Hendrickson WK, Xie G, Rahn DD, Amundsen CL, Hokanson JA, Bradley M, Smith AL, Sung VW, Visco AG, Luo S, Jelovsek JE. Predicting outcomes after intradetrusor onabotulinumtoxina for non-neurogenic urgency incontinence in women. Neurourol Urodyn. 2022 Jan;41(1):432-447. PMCID: PMC9014828
18. Hokanson JA, Langdale CL, Grill WM. Pathways and parameters of sacral neuromodulation in rats. Am J Physiol Renal Physiol. 2023 Dec 01;325(6):F757-F769. PMCID: PMC10874681
19. Lai HH, Rutlin J, Smith AR, Helmuth ME, Hokanson JA, Yang CC, Clemens JQ, Magnotta VA, Bretschneider CE, Kenton K, DeLancey JOL, John K, Kirkali Z, Shimony JS. Structural Changes in Brain White Matter Tracts Associated With Overactive Bladder Revealed by Diffusion Tensor Magnetic Resonance Imaging: Findings From a Symptoms of Lower Urinary Tract Dysfunction Research Network Cross-Sectional Case-Control Study. J Urol. 2024 Aug;212(2):351-361. PMCID: PMC11233244
20. Luebke MC, Neuner JM, Balza J, Davidson ERW, Hokanson JA, Marowski S, Corey O'Connor R, Schmitt E, Winn AN, Flynn KE. Developing a urinary incontinence primary care pathway: a mixed methods study. Fam Pract. 2024 Oct 08;41(5):798-806. PMCID: PMC11461143
21. Hendrickson WK, Zhang C, Hokanson JA, Nygaard IE, Presson AP. Predicting success using response after lead implantation with sacral neuromodulation for urgency incontinence. Neurourol Urodyn. 2024 Nov;43(8):1776-1783. PMCID: PMC11495989
22. He W, Slavik N, Braun J, Samadifam F, Hokanson JA. Faster bladder filling in rats reduces detrusor overactivity but worsens (i.e., decreases) bladder compliance. Am J Physiol Renal Physiol. 2024 Dec 01;327(6):F985-F993.
23. Hokanson JA, DeLancey JOL, Kirby AC, Gillespie B, Lai HH, Kreder KJ, Bretschneider CE, Slavik N, Andrews C, Andreev V, Black L, Richardson S, Kenton K, Kirkali Z, Yang CC, Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Study Group. Expanded Physiological Testing of the Lower Urinary Tract in Asymptomatic Women and Those With Urgency Urinary Incontinence: Findings From the LURN-Organ Study. Neurourol Urodyn. 2025 Jun;44(5):987-996. PMCID: PMC12414437
24. Bretschneider CE, Smerdon C, Bieber B, Goodrich N, Griffith J, Lai HH, Hokanson JA, Kirby AC, Smith A, Guerrero M, Gutta S, Flynn KE, John K, Bradley CS, LURN Study Group. Sexual function in women with bothersome lower urinary tract symptoms: findings from the symptoms of lower urinary tract dysfunction research network (LURN) cohort study. J Sex Med. 2025 Jun 03;22(6):1035-1042.
25. Yang CC, Hokanson JA, Kirby AC, Gillespie BW, Lai HH, Kreder KJ, Bretschneider CE, Kirkali Z, Delancey JOL. Lessons learned from conducting a multi-center lower urinary tract physiology study: the LURN experience Continence. March 2026;17.
26. Hokanson JA, Ayers CA, Gaunt RA, Bruns TM, Weber DJ. Effects of spatial and temporal parameters of primary afferent microstimulation on neural responses evoked in primary somatosensory cortex of an anesthetized cat. Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:7533-6. PMCID: PMC3475719
27. Bradley CS, Hokanson JA, Francis SL, Bieber B, Laddu D, Amundsen CL, Bretschneider CE, Clemens JQ, Collins S, Kenton K, Lai HH, Andreev VP, Glaser AP, Helfand BT, Andrews C, Graff J, Kirkali Z, Kreder KJ. The LURN urinary urgency and lifestyle wearable tracker (ULTra) study: Design and feasibility Continence. September 2026;19.
 
Books, Chapters, and Reviews
1. Fisher LE, Hokanson JA, Weber DJ. Neuroprostheses for somatosensory function Implantable Neuroprostheses for Restoring Function. March 04, 2015:127-151.
2. Hokanson JA, Amundsen CL, Grill WM. Neuroprosthetic control of lower urinary tract function Neuroprosthetics Theory and Practice Second Edition. 10 March 2017:537-565.
 
Non-Refereed Journal Publications/Original Papers
1. Yang CC, Hokanson JA, Keast JR. Advancing our understanding of the neural control of the female human urethra. Neurourol Urodyn. 2022 Jan;41(1):35-41. PMCID: PMC8738110
2. Hokanson JA, DeLancey JOL. Urethral failure is a critical factor in female urinary incontinence. Now what? Neurourol Urodyn. 2022 Feb;41(2):532-538. PMCID: PMC8892071
3. DeLancey JO, Hokanson JA. Reply to: The case against urethral failure is not a critical factor in female urinary incontinence. Now what? The integral theory system. Neurourol Urodyn. 2022 Nov;41(8):1934-1937. PMCID: PMC9633378
4. Dunivan GC, Ackenbom MF, Alperin M, Anger JT, Antosh DD, Bharucha AE, Birder LA, Boyd SS, Bradley MS, Brehman EH, Brito LGO, Brown HW, Brown O, Burnett LA, Caldwell LE, Carter-Brooks CM, Chermanksy CJ, Cichowski SB, Connell KA, Delancey JOL, Damaser MS, De Nisco NJ, Dubinskaya A, Glass DH, Guess MK, Hale DS, Hannan JL, High RA, Hokanson JA, Jacobs KM, Kelley RS, Kisby CK, Kravitz E, Lowder JL, Markland AD, Meister MRL, Meyer I, Moalli PA, Mysorekar IU, Parker-Autry CY, Richter HE, Rogers RG, Rolston R, Rubin RS, Sheyn D, Shinnick JK, Siddiqui NY, Suyama JA, Uloko MI, Walter JE, Welch EK, Wolfe AJ, Zeno A, McDermott CD. National Urogynecology Research Agenda: A Path Forward for Advancing the Treatment and Management of Pelvic Floor Disorders Urogynecology. 1 November 2023;29(11):851-855.
 
Abstracts
1. James Hokanson, Victor Andreev, Calvin Andrews, Anna Kirby, Brenda Gillespie, Farshad Samadifam, Claire Yang, John DeLancey (2026) Urgency urinary incontinence phenotypes as determined by cluster analysis of lower urinary tract physiological testing data: a LURN II organ study, Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, San Juan, Puerto Rico
2. Lucky Chaudhary, Bhavana Talluri, Wei He, Zachary Smith, Firoj Alom, Aaron D. Mickle, James A. Hokanson (2025) Mapping bladder and tibial nerve convergence in spinal cord using pseudorabies virus tracing and tibial nerve stimulation, NIDDK CAIRIBU, Madison, Wisconsin
3. Wei He, Farshad Samadifam, James A. Hokanson (2025) Development of a low-cost, reliable catheter for urethral pressure profile measurements in anesthetized rats. NIDDK CAIRIBU, Madison, Wisconsin
4. Farshad Samadifam, Wei He, Budde M, Greenberg A, Hokanson JA (2025) Functional MRI Analysis of Overactive Bladder: Brain and Brainstem Mechanisms and the Role of Tibial Nerve Stimulation. NIDDK CAIRIBU, Madison, Wisconsin
5. Slavik NA, Hokanson JA (2025) Impact of Stimulation Location on Bladder Inhibition from Tibial Nerve Stimulation in the Female Rat, Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Palm Springs, California
6. He W, Samadifam F, Hokanson JA (2025) Application of a Low-Cost, Reliable Catheter for Urethral Pressure Profile in Anesthetized Rats, Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Palm Springs, California
7. Slavik NA, Hokanson JA (2024) Impact of Stimulation Location on Bladder Inhibition from Tibial Nerve Stimulation in the Female Rat, Society for Neuroscience, Chicago, Illinois
8. He W, Samadifam F, Hokanson JA (2024) Application of a Low-Cost, Reliable Catheter For Urethral Pressure Profile in Anesthetized Rats, NIDDK CAIRIBU, Milwaukee, Wisconsin
9. Samadifam F, He W, Slavik N, Budde M, Greenberg A, Hokanson JA (2024) Functional MRI Analysis of Overactive Bladder: Brain and Brainstem Mechanisms and the Role of Tibial Nerve Stimulation, NIDDK CAIRIBU, Milwaukee, Wisconsin
10. Samadifam F, Banerjee A, Braun J, He W, Slavik N, Hendrickson WK, Amundsen CL, Hokanson JA (2024) Outcome prediction for sacral neuromodulation therapy in women with non-neurogenic urgency incontinence: a machine learning approach, Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Fort Lauderdale, Florida
11. Samadifam F, Fairchild RJ, Di Martino M, Aquino W, Routh JC, Hokanson JA (2023) “Predicting urinary tract infection and hydronephrosis in spina bifida patients using machine learning” Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Nashville, Tennessee
12. He W, Hokanson JA (2023) “Impact of Bladder Filling Rate on Cystometric Variables in Anesthetized Rats” Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Nashville, Tennessee
13. Braun J, Hokanson JA (2023) “Initial experience conducting void spot assays in rats” Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Nashville, Tennessee
14. Braun J, Hokanson JA (2023) “Initial experience conducting void spot assays in rats” Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Nashville, Tennessee
15. Hokanson JA, Langdale CL, Grill WM (2023) “Sacral nerve stimulation in rats: parameters & pathways” Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Nashville, Tennessee
16. He W, Hokanson JA (2022) “Impact of Bladder Filling Rate on Cystometric Variables in Anesthetized Rats” NIDDK CAIRIBU, Bethesda, MD
17. Fairchild RJ, Aksenov LI, Hobbs KT, Aquino W, Hokanson JA, Routh JC (2022) “Using machine learning of urodynamics to predict clinical outcomes in patients with spina bifida” SPU Pediatric Urology Fall Congress
18. Hobbs KT, Choe N, Aksenov LI, Aquino W, Routh JC, Hokanson JA (2021) “Utilization of Machine Learning for the Detection of Detrusor Overactivity on Urodynamics” SPU Pediatric Urology Fall Congress
19. Hendrickson WK, Xie G, Rahn DD, Bradley MB, Sung V, Hokanson JA, Smith AL, Visco A, Amundsen CL, Luo S, Jelovsek JE (2021) “Development of Models Predicting Treatment Efficacy and Need for Self-Catheterization After Intradetrusor OnabotulinumToxinA for Non-Neurogenic Urgency Incontinence in Women” Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (Online)
20. Hokanson JA, Langdale CL, Grill WM (2020) “Sacral Neuromodulation in Rats: Parameters and Pathways” Collaborating for the Advancement of Interdisciplinary Research in Benign Urology (Online)(Best Poster Awardee)
21. Langdale CL, Hokanson JA, Degoski D, Milliken P, Grill WM (2019) “Stimulation of the pudendal sensory nerve alters voiding behavior in conscious unrestrained Wistar rats” Society for Neuroscience, Chicago, Illinois
22. Hokanson JA, Grill WM, Amundsen CA (2019) “Intraurethral stimulation: a possible way to increase intraurethral pressures and prevent urgency incontinence episodes” Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction, Miami, Florida
23. Hokanson JA, Langdale CL, Milliken P, Sridhar A, Grill WM (2018) “State-dependent pudendal nerve stimulation increases bladder capacity and voiding efficiency in rats and cats” Society for Neuroscience, San Diego, California
24. Hokanson JA, Langdale CL, Milliken P, Sridhar A, Grill WM (2018) “State-dependent pudendal nerve stimulation to increase bladder capacity and voiding efficiency in rats” Neural Interfaces Conference, Minneapolis, Minnesota
25. Langdale CL, Hokanson JA, Milliken P, Grill WM (2017) “Voiding behavior in awake unrestrained untethered spontaneously hypertensive and control rats” Society for Neuroscience, Washington, D.C.
26. Hokanson JA, Langdale CL, Sridhar A, Milliken P, Grill WM (2017) “State-dependent stimulation of the pudendal nerve increases bladder capacity and voiding efficiency” Society for Neuroscience, Washington, D.C.
27. Langdale CL, Hokanson JA, Sridhar A, Grill WM (2016) “Prostaglandin E2 installation as an overactive bladder model in cats” Society for Neuroscience, San Diego, California
28. Hokanson JA, Langdale CL, Sridhar A, Grill WM (2016) “OAB Without an overactive bladder: insights from an acute prostaglandin E2 rat model” Society for Neuroscience, San Diego, California
29. Hokanson JA, Langdale CL, Grill WM (2016) “OAB Without an overactive bladder” Society for Urodynamics and Female Urology, New Orleans, Louisiana
30. Langdale CL, Hokanson JA, Sridhar A, Grill WM (2015) “Pelvic nerve stimulation restores bladder capacity and voiding efficiency in rat prostaglandin E2 overactive bladder model” Society for Neuroscience, Chicago, Illinois
31. Hokanson JA, Langdale, CA, Sridhar A, Grill WM (2015) “Pudendal nerve stimulation restores bladder capacity in rat prostaglandin E2 overactive bladder model”
32. Fisher LE, Hokanson JA, Gaunt RA, Weber DJ (2013) “A method for automatic identification of peripheral nerve microstimulation thresholds from electroneurogram signals” Society for Neuroscience, San Diego, California
33. Hokanson JA, Ayers CA, Gaunt RA, Weber DJ (2012) “Nonlinear recruitment of primary afferent neurons from simultaneous stimulation” Society for Neuroscience, New Orleans, Lousiana
34. Bruns TM, Gaunt RA, Ayers CA, Hokanson JA, Weber DJ (2012) "Bladder and pelvic activity recorded with chronic microelectrode implants in feline sacral dorsal root ganglia" Society for Neuroscience, New Orleans, Lousiana
35. Wagenaar JB, Hokanson JA, Ayers CA, Weber DJ (2010) “Development of an efficient data-management system in Matlab” Society for Neuroscience, San Diego, California
36. Hokanson JA, Ayers CA, Gaunt RA, Weber DJ (2010) “Novel stimulation paradigm to provide somatosensory feedback in a neural prosthesis” Society for Neuroscience, San Diego, California
37. Bourbeau DJ, Hokanson JA, Rubin JE, Ermentrout GB, Weber DJ (2010) “A computational model for simulating recruitment of peripheral nerve fibers by intraneural microstimulation” Society for Neuroscience, San Diego, California
38. Ayers CA, Gaunt RA, Hokanson JA, Weber DJ (2010) “Primary somatosensory cortex responses to simple patterns of primary afferent microstimulation in L6/L7 dorsal root ganglia of anesthetized cats” Society for Neuroscience, San Diego, California
39. Hokanson JA, Yu B, Ayers CA, Weber DJ (2010) “Quantifying Neural Responses to Natural and Artificial Stimuli in Large Populations of Cortical Neurons” Neural Interfaces Conference, Long Beach, California
40. Perich M, Hokanson JA, Gaunt RA, Weber DJ (2009) “Improving Limb-State Decoding Using a Liquid State Machine” Biomedical Engineering Society, Pittsburgh, Pennsylvania
41. Kim J, Wilson JA, Hippensteel J, Hokanson JA, Wang W, Smith K, Otto KJ, Shain W, Weber DJ, Krugner-Higby LA, Moran DW, Williams JC (2008) “A Cortical microECoG Platform Utilizing Thin Film Polymer Electrode Arrays” Society for Neuroscience, Washington D.C.
42. Hokanson JA, Wagenaar JB, Weber DJ (2008) “Recruitment of DRG neurons by electrical microstimulation” Society for Neuroscience, Washington D.C.
43. Wagenaar JB, Hokanson JA, Ventura V, Weber DJ (2008) “Real-time feedback control of functional electrical stimulation based on primary afferent recordings” Biomedical Engineering Society, St. Louis, Missouri
44. Hokanson JA, Wagenaar JB, Weber DJ (2008) “Recruitment of DRG Neurons by Electrical Microstimulation” Biomedical Engineering Society, St. Louis, Missouri
45. Bourbeau DJ, Hokanson JA, Weber DJ (2008) “A Computational Model for Examining Activation of Peripheral Neurons by Electrical Microstimulation” Biomedical Engineering Society, St. Louis, Missouri
46. Hokanson JA, Wagenaar JB, Ventura V, Weber DJ (2007) “Neural Responses in Somatosensory Cortex to Multichannel Microstimulation of Primary Afferent Neurons” Society for Neuroscience, San Diego, California
 
Patents
1. Grill WM, Hokanson JA, Langdale CL “State-dependent pudendal nerve stimulation for bladder control” U.S. Patent No. 12,337,174, June 24, 2025
2. Grill WM, Hokanson JA, Langdale CL “Systems and Methods for Targeted Sacral Nerve Stimulation” U.S. Patent No. 12,329,967, June 17, 2025
3. Grill WM, Hokanson JA, Langdale CL “Systems and Methods for Targeted Sacral Nerve Stimulation” U.S. Patent No. 12,064,627, Aug 20, 2024
4. Grill WM, Hokanson JA, Langdale CL “State-Dependent Pudendal Nerve Stimulation for Bladder Control” U.S. Patent No. 11,911,614, Feb 26, 2024
5. Grill WM, Hokanson JA, Langdale CL “State-Dependent Peripheral Neuromodulation to Treat Bladder Dysfunction,” U.S. Patent No. 11,617,886, April, 4, 2023
6. Grill WM, Hokanson JA, Langdale CL “State-Dependent Pudendal Nerve Stimulation for Bladder Control” U.S. Patent No. 11,278,721, Mar 22, 2022
7. Grill WM, Hokanson JA, Langdale CL “State-Dependent Peripheral Neuromodulation to Treat Bladder Dysfunction,” U.S. Patent No. 10,722,708 , Jul 28, 2020