CURRICULUM VITAE
John F. LaDisa PhD
John F. LaDisa PhD
Professor
Department of Pediatrics
Division of Pediatrics Cardiology
Department of Pediatrics
Division of Pediatrics Cardiology
OFFICE ADDRESS: |
8701 West Watertown Plank Road |
Milwaukee, WI 53226 |
EDUCATION: |
1995 - 2000 Biomechanical Engineering, Marquette University |
2000 - 2001 Biomechanical Engineering, Marquette University |
2000 - 2004 Biomedical Engineering, Marquette University |
2004 - 2006 Postdoctoral Fellowship - Pediatrics and Bioengineering, Stanford University |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||
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BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. LaDisa JF Jr, Hettrick DA, Olson LE, Guler I, Gross ER, Kress TT, Kersten JR, Warltier DC, Pagel PS. Stent implantation alters coronary artery hemodynamics and wall shear stress during maximal vasodilation. J Appl Physiol (1985). 2002 Dec;93(6):1939-46. |
2. Tanaka K, Weihrauch D, Kehl F, Ludwig LM, LaDisa JF Jr, Kersten JR, Pagel PS, Warltier DC. Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. Anesthesiology. 2002 Dec;97(6):1485-90. |
3. Gross ER, LaDisa JF Jr, Weihrauch D, Olson LE, Kress TT, Hettrick DA, Pagel PS, Warltier DC, Kersten JR. Reactive oxygen species modulate coronary wall shear stress and endothelial function during hyperglycemia. Am J Physiol Heart Circ Physiol. 2003 May;284(5):H1552-9. |
4. Kehl F, Krolikowski JG, LaDisa JF Jr, Kersten JR, Warltier DC, Pagel PS. Adenosine type 1 (A1) receptors mediate protection against myocardial infarction produced by chronic, intermittent ingestion of ethanol in dogs. Int J Cardiol. 2003 Apr;88(2-3):175-82. |
5. LaDisa JF Jr, Guler I, Olson LE, Hettrick DA, Kersten JR, Warltier DC, Pagel PS. Three-dimensional computational fluid dynamics modeling of alterations in coronary wall shear stress produced by stent implantation. Ann Biomed Eng. 2003 Sep;31(8):972-80. |
6. Rys R, LaDisa JF Jr, Tessmer JP, Gu W, Kersten JR, Warltier DC, Pagel PS. An automated coronary artery occlusion device for stimulating collateral development in vivo. J Pharmacol Toxicol Methods. 2002;48(2):111-8. |
7. Kehl F, Ladisa JF Jr, Hettrick DA, Kersten JR, Warltier DC, Pagel PS. Influence of isoflurane on left atrial function in dogs with pacing-induced cardiomyopathy: evaluation with pressure-volume relationships. J Cardiothorac Vasc Anesth. 2003 Dec;17(6):709-14. |
8. LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Audi SH, Kersten JR, Warltier DC, Pagel PS. Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery. J Appl Physiol (1985). 2004 Jul;97(1):424-30; discussion 416. |
9. LaDisa JF Jr, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR. Cardioprotection by glucose-insulin-potassium: dependence on KATP channel opening and blood glucose concentration before ischemia. Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H601-7. |
10. LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Kersten JR, Warltier DC, Pagel PS. Circumferential vascular deformation after stent implantation alters wall shear stress evaluated with time-dependent 3D computational fluid dynamics models. J Appl Physiol (1985). 2005 Mar;98(3):947-57. |
11. LaDisa JF Jr, Olson LE, Molthen RC, Hettrick DA, Pratt PF, Hardel MD, Kersten JR, Warltier DC, Pagel PS. Alterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries. Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2465-75. |
12. LaDisa JF Jr, Meier HT, Olson LE, Kersten JR, Warltier DC, Pagel PS. Antegrade iliac artery stent implantation for the temporal and spatial examination of stent-induced neointimal hyperplasia and alterations in regional fluid dynamics. J Pharmacol Toxicol Methods. 2005;51(2):115-21. |
13. Ladisa JF Jr, Olson LE, Ropella KM, Molthen RC, Haworth ST, Kersten JR, Warltier DC, Pagel PS. Microfocal X-ray computed tomography post-processing operations for optimizing reconstruction volumes of stented arteries during 3D computational fluid dynamics modeling. Comput Methods Programs Biomed. 2005 Aug;79(2):121-34. |
14. LaDisa JF Jr, Olson LE, Hettrick DA, Warltier DC, Kersten JR, Pagel PS. Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening. Biomed Eng Online. 2005 Oct 26;4:59. PMCID: PMC1276824 |
15. LaDisa JF Jr, Olson LE, Douglas HA, Warltier DC, Kersten JR, Pagel PS. Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling. Biomed Eng Online. 2006 Jun 16;5:40. PMCID: PMC1550410 |
16. Kim HJ, Vignon-Clementel IE, Figueroa CA, LaDisa JF, Jansen KE, Feinstein JA, Taylor CA. On coupling a lumped parameter heart model and a three-dimensional finite element aorta model. Ann Biomed Eng. 2009 Nov;37(11):2153-69. |
17. LaDisa JF Jr, Bowers M, Harmann L, Prost R, Doppalapudi AV, Mohyuddin T, Zaidat O, Migrino RQ. Time-efficient patient-specific quantification of regional carotid artery fluid dynamics and spatial correlation with plaque burden. Med Phys. 2010 Feb;37(2):784-92. PMCID: PMC2826384 |
18. Moore JE Jr, Timmins LH, Ladisa JF Jr. Coronary artery bifurcation biomechanics and implications for interventional strategies. Catheter Cardiovasc Interv. 2010 Nov 15;76(6):836-43. |
19. Williams AR, Koo BK, Gundert TJ, Fitzgerald PJ, LaDisa JF Jr. Local hemodynamic changes caused by main branch stent implantation and subsequent virtual side branch balloon angioplasty in a representative coronary bifurcation. J Appl Physiol (1985). 2010 Aug;109(2):532-40. |
20. Ladisa JF Jr, Taylor CA, Feinstein JA. AORTIC COARCTATION: RECENT DEVELOPMENTS IN EXPERIMENTAL AND COMPUTATIONAL METHODS TO ASSESS TREATMENTS FOR THIS SIMPLE CONDITION. Prog Pediatr Cardiol. 2010 Dec 01;30(1):45-49. PMCID: PMC2997687 |
21. Gundert TJ, Shadden SC, Williams AR, Koo BK, Feinstein JA, Ladisa JF Jr. A rapid and computationally inexpensive method to virtually implant current and next-generation stents into subject-specific computational fluid dynamics models. Ann Biomed Eng. 2011 May;39(5):1423-37. |
22. LaDisa JF Jr, Dholakia RJ, Figueroa CA, Vignon-Clementel IE, Chan FP, Samyn MM, Cava JR, Taylor CA, Feinstein JA. Computational simulations demonstrate altered wall shear stress in aortic coarctation patients treated by resection with end-to-end anastomosis. Congenit Heart Dis. 2011;6(5):432-43. PMCID: PMC3208403 |
23. Migrino RQ, Bowers M, Harmann L, Prost R, LaDisa JF Jr. Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness. J Cardiovasc Magn Reson. 2011 Aug 03;13(1):37. PMCID: PMC3166901 |
24. LaDisa JF Jr, Alberto Figueroa C, Vignon-Clementel IE, Kim HJ, Xiao N, Ellwein LM, Chan FP, Feinstein JA, Taylor CA. Computational simulations for aortic coarctation: representative results from a sampling of patients. J Biomech Eng. 2011 Sep;133(9):091008. PMCID: PMC3705983 |
25. Menon A, Wendell DC, Wang H, Eddinger TJ, Toth JM, Dholakia RJ, Larsen PM, Jensen ES, Ladisa JF Jr. A coupled experimental and computational approach to quantify deleterious hemodynamics, vascular alterations, and mechanisms of long-term morbidity in response to aortic coarctation. J Pharmacol Toxicol Methods. 2012 Jan;65(1):18-28. PMCID: PMC3288451 |
26. Gundert TJ, Marsden AL, Yang W, LaDisa JF Jr. Optimization of cardiovascular stent design using computational fluid dynamics. J Biomech Eng. 2012 Jan;134(1):011002. |
27. Coogan JS, Chan FP, Ladisa JF Jr, Taylor CA, Hanley FL, Feinstein JA. Computational fluid dynamic simulations for determination of ventricular workload in aortic arch obstructions. J Thorac Cardiovasc Surg. 2013 Feb;145(2):489-495.e1. |
28. Gundert TJ, Marsden AL, Yang W, Marks DS, LaDisa JF Jr. Identification of hemodynamically optimal coronary stent designs based on vessel caliber. IEEE Trans Biomed Eng. 2012 Jul;59(7):1992-2002. |
29. Wendell DC, Samyn MM, Cava JR, Ellwein LM, Krolikowski MM, Gandy KL, Pelech AN, Shadden SC, LaDisa JF Jr. Including aortic valve morphology in computational fluid dynamics simulations: initial findings and application to aortic coarctation. Med Eng Phys. 2013 Jun;35(6):723-35. PMCID: PMC3577975 |
30. Menon A, Eddinger TJ, Wang H, Wendell DC, Toth JM, LaDisa JF Jr. Altered hemodynamics, endothelial function, and protein expression occur with aortic coarctation and persist after repair. Am J Physiol Heart Circ Physiol. 2012 Dec 01;303(11):H1304-18. PMCID: PMC3532538 |
31. Kwon S, Feinstein JA, Dholakia RJ, Ladisa JF Jr. Quantification of local hemodynamic alterations caused by virtual implantation of three commercially available stents for the treatment of aortic coarctation. Pediatr Cardiol. 2014 Apr;35(4):732-40. PMCID: PMC3959287 |
32. Quam DJ, Gundert TJ, Ellwein L, Larkee CE, Hayden P, Migrino RQ, Otake H, LaDisa JF Jr. Immersive visualization for enhanced computational fluid dynamics analysis. J Biomech Eng. 2015 Mar;137(3):0310041-03100412. PMCID: PMC4321107 |
33. Samyn MM, Dholakia R, Wang H, Co-Vu J, Yan K, Widlansky ME, LaDisa JF, Simpson P, Alemzadeh R. Cardiovascular magnetic resonance imaging-based computational fluid dynamics/fluid-structure interaction pilot study to detect early vascular changes in pediatric patients with type 1 diabetes. Pediatr Cardiol. 2015 Apr;36(4):851-61. |
34. LaDisa JF Jr, Bozdag S, Olson J, Ramchandran R, Kersten JR, Eddinger TJ. Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention? PLoS One. 2015;10(7):e0133356. PMCID: PMC4514739 |
35. Wang H, Weihrauch D, Kersten JR, Toth JM, Passerini AG, Rajamani A, Schrepfer S, LaDisa JF Jr. Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats. Am J Physiol Heart Circ Physiol. 2015 Oct;309(7):H1130-40. PMCID: PMC4865061 |
36. Chiastra C, Wu W, Dickerhoff B, Aleiou A, Dubini G, Otake H, Migliavacca F, LaDisa JF Jr. Computational replication of the patient-specific stenting procedure for coronary artery bifurcations: From OCT and CT imaging to structural and hemodynamics analyses. J Biomech. 2016 Jul 26;49(11):2102-2111. |
37. Ellwein L, Marks DS, Migrino RQ, Foley WD, Sherman S, LaDisa JF Jr. Image-based quantification of 3D morphology for bifurcations in the left coronary artery: Application to stent design. Catheter Cardiovasc Interv. 2016 Jun;87(7):1244-55. PMCID: PMC4896847 |
38. Wendell DC, Samyn MM, Cava JR, Krolikowski MM, LaDisa JF Jr. The Impact of Cardiac Motion on Aortic Valve Flow Used in Computational Simulations of the Thoracic Aorta. J Biomech Eng. 2016 Sep 01;138(9):0910011-09100111. PMCID: PMC4967883 |
39. Ellwein L, Samyn MM, Danduran M, Schindler-Ivens S, Liebham S, LaDisa JF Jr. Toward translating near-infrared spectroscopy oxygen saturation data for the non-invasive prediction of spatial and temporal hemodynamics during exercise. Biomech Model Mechanobiol. 2017 Feb;16(1):75-96. PMCID: PMC5217163 |
40. Wendell DC, Friehs I, Samyn MM, Harmann LM, LaDisa JF Jr. Treating a 20 mm Hg gradient alleviates myocardial hypertrophy in experimental aortic coarctation. J Surg Res. 2017 Oct;218:194-201. PMCID: PMC5679105 |
41. Kandail HS, Trivedi SD, Shaikh AC, Bajwa TK, O'Hair DP, Jahangir A, LaDisa JF Jr. Impact of annular and supra-annular CoreValve deployment locations on aortic and coronary artery hemodynamics. J Mech Behav Biomed Mater. 2018 Oct;86:131-142. |
42. LaDisa JF Jr, Tomita-Mitchell A, Stamm K, Bazan K, Mahnke DK, Goetsch MA, Wegter BJ, Gerringer JW, Repp K, Palygin O, Zietara AP, Krolikowski MM, Eddinger TJ, Alli AA, Mitchell ME. Human genotyping and an experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta. Physiol Genomics. 2019 Jun 01;51(6):177-185. PMCID: PMC6620646 |
43. Boster KAS, Dong M, Oakes JM, Bellini C, Rayz VL, LaDisa JF, Parker D, Wilson NM, Shadden SC, Marsden AL, Goergen CJ. Integrated Image-Based Computational Fluid Dynamics Modeling Software as an Instructional Tool. J Biomech Eng. 2020 Nov 01;142(11). PMCID: PMC7580653 |
44. Marklin RW Jr, Toll AM, Bauman EH, Simmins JJ, LaDisa JF Jr, Cooper R. Do Head-Mounted Augmented Reality Devices Affect Muscle Activity and Eye Strain of Utility Workers Who Do Procedural Work? Studies of Operators and Manhole Workers. Hum Factors. 2022 Mar;64(2):305-323. PMCID: PMC8935469 |
45. Razavi A, Sachdeva S, Frommelt PC, LaDisa JF Jr. Patient-Specific Numerical Analysis of Coronary Flow in Children With Intramural Anomalous Aortic Origin of Coronary Arteries. Semin Thorac Cardiovasc Surg. 2021 Spring;33(1):155-167. |
46. Ghorbanniahassankiadeh A, Marks DS, LaDisa JF. Correlation of Computational Instantaneous Wave-Free Ratio With Fractional Flow Reserve for Intermediate Multivessel Coronary Disease. J Biomech Eng. 2021 May 01;143(5). |
47. Kazik HB, Kandail HS, LaDisa JF Jr, Lincoln J. Molecular and Mechanical Mechanisms of Calcification Pathology Induced by Bicuspid Aortic Valve Abnormalities. Front Cardiovasc Med. 2021;8:677977. PMCID: PMC8187581 |
48. Nouri MZ, Yu L, Liu LP, Chacko KM, Denslow ND, LaDisa JF Jr, Alli AA. Increased endothelial sodium channel activity by extracellular vesicles in human aortic endothelial cells: putative role of MLP1 and bioactive lipids. Am J Physiol Cell Physiol. 2021 Sep 01;321(3):C535-C548. PMCID: PMC8461814 |
49. Razavi A, Sachdeva S, Frommelt PC, LaDisa JF. Computational Assessment of Hemodynamic Significance in Patients With Intramural Anomalous Aortic Origin of the Coronary Artery Using Virtually Derived Fractional Flow Reserve and Downstream Microvascular Resistance. J Biomech Eng. 2022 Mar 01;144(3). |
50. Gorzek S, LaDisa JF Jr. Assessment of Reflux From Needleless Connectors: Blinded Comparison of Category Designation to Benchtop Function Using a Venous Simulator. J Infus Nurs. 2021 Nov-Dec 01;44(6):323-330. |
51. Camarda JA, Dholakia RJ, Wang H, Samyn MM, Cava JR, LaDisa JF Jr. A Pilot Study Characterizing Flow Patterns in the Thoracic Aorta of Patients With Connective Tissue Disease: Comparison to Age- and Gender-Matched Controls <i>via</i> Fluid Structure Interaction. Front Pediatr. 2022;10:772142. PMCID: PMC9114664 |
52. Ghorbannia A, Ellepola CD, Woods RK, Ibrahim EH, Maadooliat M, Ramirez HM, LaDisa JF Jr. Clinical, Experimental, and Computational Validation of a New Doppler-Based Index for Coarctation Severity Assessment. J Am Soc Echocardiogr. 2022 Dec;35(12):1311-1321. PMCID: PMC9729418 |
53. Yu L, Nouri MZ, Liu LP, Bala N, Denslow ND, LaDisa JF Jr, Alli AA. C Type Natriuretic Peptide Receptor Activation Inhibits Sodium Channel Activity in Human Aortic Endothelial Cells by Activating the Diacylglycerol-Protein Kinase C Pathway. Int J Mol Sci. 2022 Nov 12;23(22). PMCID: PMC9698807 |
54. Venn J, Larkee CE, Garcia GJM, Rayz VL, LaDisa JF Jr. A workflow for viewing biomedical computational fluid dynamics results and corresponding data within virtual and augmented reality environments. Front Med Technol. 2023;5:1096289. PMCID: PMC9996009 |
55. Azarnoosh J, Ghorbannia A, Ibrahim EH, Jurkiewicz H, Kalvin L, LaDisa JF Jr. Temporal evolution of mechanical stimuli from vascular remodeling in response to the severity and duration of aortic coarctation in a preclinical model. Sci Rep. 2023 May 23;13(1):8352. PMCID: PMC10205817 |
56. Ghorbannia A, LaDisa JF Jr. Intravascular imaging of angioplasty balloon under-expansion during pre-dilation predicts hyperelastic behavior of coronary artery lesions. Front Bioeng Biotechnol. 2023;11:1192797. PMCID: PMC10240066 |
57. Wolfe JT, He W, Kim MS, Liang HL, Shradhanjali A, Jurkiewicz H, Freudinger BP, Greene AS, LaDisa JF Jr, Tayebi L, Mitchell ME, Tomita-Mitchell A, Tefft BJ. 3D-bioprinting of patient-derived cardiac tissue models for studying congenital heart disease. Front Cardiovasc Med. 2023;10:1162731. PMCID: PMC10247285 |
58. Ghorbannia A, Maadooliat M, Woods RK, Audi SH, Tefft BJ, Chiastra C, Ibrahim ESH, LaDisa JF. Aortic Remodeling Kinetics in Response to Coarctation-Induced Mechanical Perturbations. Biomedicines. 2023 Jun 25;11(7). PMCID: PMC10377168 |
59. Samant S, Bakhos JJ, Wu W, Zhao S, Kassab GS, Khan B, Panagopoulos A, Makadia J, Oguz UM, Banga A, Fayaz M, Glass W, Chiastra C, Burzotta F, LaDisa JF Jr, Iaizzo P, Murasato Y, Dubini G, Migliavacca F, Mickley T, Bicek A, Fontana J, West NEJ, Mortier P, Boyers PJ, Gold JP, Anderson DR, Tcheng JE, Windle JR, Samady H, Jaffer FA, Desai NR, Lansky A, Mena-Hurtado C, Abbott D, Brilakis ES, Lassen JF, Louvard Y, Stankovic G, Serruys PW, Velazquez E, Elias P, Bhatt DL, Dangas G, Chatzizisis YS. Artificial Intelligence, Computational Simulations, and Extended Reality in Cardiovascular Interventions. JACC Cardiovasc Interv. 2023 Oct 23;16(20):2479-2497. |
60. Ghorbannia A, Spearman AD, Sawalhi S, Woods RK, Maadooliat M, LaDisa JF Jr. Consistency of the continuous flow pressure gradient despite aortic arch anomalies co-existing with coarctation. medRxiv. 2023 Oct 30. PMCID: PMC10635219 |
61. Ghorbannia A, Jurkiewicz H, Nasif L, Ahmed A, Co-Vu J, Maadooliat M, Woods RK, LaDisa JF Jr. Coarctation duration and severity predict risk of hypertension precursors in a preclinical model and hypertensive status among patients. medRxiv. 2024 Mar 19. PMCID: PMC10635238 |
62. Peirce-Cottler SM, Sander EA, Fisher MB, Deymier AC, LaDisa JF Jr, O'Connell G, Corr DT, Han B, Singh A, Wilson SE, Lai VK, Clyne AM. A Systems Approach to Biomechanics, Mechanobiology, and Biotransport. J Biomech Eng. 2024 Apr 01;146(4). PMCID: PMC12047288 |
63. Ghorbannia A, Jurkiewicz H, Nasif L, Ahmed A, Co-Vu J, Maadooliat M, Woods RK, LaDisa JF Jr. Coarctation Duration and Severity Predict Risk of Hypertension Precursors in a Preclinical Model and Hypertensive Status Among Patients. Hypertension. 2024 May;81(5):1115-1124. PMCID: PMC11023794 |
64. Yu L, Bala N, Nguyen VL, Kessler L, LaDisa JF, Alli AA. Activity and function of the endothelial sodium channel is regulated by the effector domain of MARCKS like protein 1 in mouse aortic endothelial cells. bioRxiv. 2024 Jun 26. PMCID: PMC11230428 |
65. Ghorbannia A, Spearman AD, Sawalhi S, Woods RK, Maadooliat M, LaDisa JF Jr. A Novel Diastolic Doppler Index Less Affected by Aortic Arch Anomalies Co-existing with Coarctation. Pediatr Cardiol. 2025 Aug;46(6):1551-1559. PMCID: PMC13042260 |
66. McLennan DI, Maldonado JR, Foerster SR, Handler SS, LaDisa JF Jr, Gudausky TM, Guillory RJ 2nd. Absorbable metal stents for vascular use in pediatric cardiology: progress and outlook. Front Cardiovasc Med. 2024;11:1410305. PMCID: PMC11334478 |
67. Keshavarz Motamed Z, Maftoon N, Dasi LP, LaDisa JF Jr. Editorial: Novel computational fluid dynamics methods for diagnosis, monitoring, prediction, and personalized treatment for cardiovascular disease and cancer metastasis. Front Bioeng Biotechnol. 2024;12:1491950. PMCID: PMC11518811 |
68. Yu L, Bala N, Nguyen VL, Kessler L, LaDisa JF Jr, Alli AA. Activity and function of the endothelial sodium channel is regulated by the effector domain of MARCKS-like protein 1 in mouse aortic endothelial cells. Am J Physiol Cell Physiol. 2025 Apr 01;328(4):C1101-C1108. PMCID: PMC13115027 |
69. Blanch-Granada A, LaDisa JF Jr, Samyn MM, Cava JR, Handler SS, Gerardin JF, Goot B, Maadooliat M, Hraška V. Hemodynamic Evaluation of Norwood Aortic Arch Geometry Compared to Native Arch Controls. J Biomech Eng. 2025 May 01;147(5). |
70. Hiebing AA, Culver MA, LaDisa JF Jr, Witzenburg CM. Computational model of coarctation of the aorta in rabbits suggests persistent ascending aortic remodeling post-correction. Biomech Model Mechanobiol. 2025 Apr;24(2):683-700. PMCID: PMC12797878 |
71. McCarthy RP, Mason PJ, Marks DS, LaDisa JF Jr. Influence of boundary conditions and blood rheology on indices of wall shear stress from IVUS-based patient-specific stented coronary artery simulations. Sci Rep. 2025 May 07;15(1):15868. PMCID: PMC12059177 |
72. Schock D, Armstrong A, Alli A, LaDisa JF. A benchtop bioreactor to impart coarctation-induced deformation and assess mechanisms of endothelial dysfunction. bioRxiv. 2025 May 28. PMCID: PMC12154653 |
73. Chiastra C, Pirola S, Saitta S, Sturla F, LaDisa JF Jr. Building digital twins for personalized cardiovascular medicine: Advances, challenges, and future directions. Comput Biol Med. 2025 Nov;198(Pt A):111122. |
74. Kazik HB, Kandail HS, Lincoln J, LaDisa JF Jr. Patient-Informed Fluid-Structure Interaction Simulations of Bicuspid Aortic Valve in Young Adults Reveal Regionalized Differences in Mechanical Stress. Ann Biomed Eng. 2026 Mar;54(3):679-696. PMCID: PMC12927076 |
75. Blanch-Granada A, Samyn MM, Handler SS, Gerardin JF, Goot B, Hraška V, Cava JR, LaDisa JF. Effect of Virtual Aortic Arch Reconstruction After Norwood Procedure on Cardiac Function, Energy Efficiency, and Wall Shear Stress from Multiscale Simulations Current Cardiovascular Imaging Reports. December 2023;16(12):117-127. |
76. Tran J, Abeysinghe E, Ladisa J, Marsden A, Pierce M. SimVascular Gateway for Education and Research Pearc 2022 Conference Series Practice and Experience in Advanced Research Computing 2022 Revolutionary Computing Connections You. 8 July 2022. |
77. LaDisa JF, Ghorbannia A, Marks DS, Mason P, Otake H. Advancements and Opportunities in Characterizing Patient-Specific Wall Shear Stress Imposed by Coronary Artery Stenting Fluids. October 2022;7(10). |
78. Kenny DP, LaDisa JF. Aortic Coarctation: Clinical Concepts, Engineering Applications, and Impact of an Integrated Medico-Engineering Approach Modelling Congenital Heart Disease Engineering A Patient Specific Therapy. 1 January 2022:43-60. |
79. LaDisa JF, Larkee CE. The MARquette Visualization Lab (MARVL): An Immersive Virtual Environment for Research, Teaching and Collaboration Frontiers in Education. 21 April 2020;5. |
80. Garstki K, Larkee C, Ladisa J. A role for immersive visualization experiences in teaching archaeology Studies in Digital Heritage. 28 June 2019;3(1):46-59. |
81. Larkee C, LaDisa J. An efficient approach to playback of stereoscopic videos using a wide field-of-view Is and T International Symposium on Electronic Imaging Science and Technology. 2016. |
82. Wilson NM, Ortiz AK, Johnson AB, Feinstein JA, LaDisa JF, Marsden A. A public repository of image-based computational models and patient-specific blood flow simulation results ASME 2013 Summer Bioengineering Conference Sbc 2013. 2013;1 A. |
83. Gundert TJ, Dholakia RJ, McMahon D, LaDisa JF. Computational fluid dynamics evaluation of equivalency in hemodynamic alterations between driver, integrity, and similar stents implanted into an idealized coronary artery Journal of Medical Devices Transactions of the ASME. 4 February 2013;7(1). |
84. Wilson NM, Ortiz AK, Johnson AB, Arko FR, Feinstein JA, LaDisa JF, Marsden A. A public repository of image-based computational models for patient-specific blood flow simulation ASME 2012 Summer Bioengineering Conference Sbc 2012. 2012:969-970. |
85. Ellwein LM, Otake H, Gundert TJ, Koo BK, Shinke T, Honda Y, Shite J, LaDisa JF. Optical Coherence Tomography for Patient-specific 3D Artery Reconstruction and Evaluation of Wall Shear Stress in a Left Circumflex Coronary Artery Cardiovascular Engineering and Technology. September 2011;2(3):212-227. |
86. Gundert TJ, Ladisa JF. Evaluation of cerebral aneurysm stent performance in a subject-specific computational model ASME 2010 Summer Bioengineering Conference Sbc 2010. 2010(PARTS A AND B):747-748. |
87. Wendell DC, Dholakia RJ, Larsen PM, Menon A, LaDisa JF. A new image-based process for quantifying hemodynamic contributions to long-term morbidity in a rabbit model of aortic coarctation Progress in Biomedical Optics and Imaging Proceedings of SPIE. 2010;7626. |
88. Gundert TJ, Hayden P, Migrino RQ, LaDisa JF. Visualization of CFD results in a virtual reality environment Proceedings of the ASME Summer Bioengineering Conference 2009 Sbc2009. 2009(PART B):741-742. |
89. Wilson NM, Migrino RQ, Harmann L, Prost RW, LaDisa JF. Modeling and realistic simulation of the carotid artery bifurcation using 3-D image segmentation implented in a commercial software package for hemodynamic simulation (CVSIM™) Proceedings of the ASME Summer Bioengineering Conference Sbc2008. 2009(PART B):797-798. |
90. LaDisa JF, Figueroa CA, Vignon-Clementel IE, Chan FP, Feinstein JA, Taylor CA. Use of computational fluid dynamics for the replication of clinical blood flowand pressure measurements and characterization of hemodynamics in the normal ascending and thoracic aorta Proceedings of the ASME Summer Bioengineering Conference 2007 Sbc 2007. 2007:511-512. |
91. Les AS, Cheng CP, Blomme MTD, Figueroa CA, LaDisa JF, Park JM, Herfkens RJ, Dalman RL, Taylor CA. Hemodynamics in human abdominal aortic aneurysms during rest and simulated exercise Proceedings of the ASME Summer Bioengineering Conference 2007 Sbc 2007. 2007:169-170. |
92. Ladisa JF, Taylor CA, Feinstein JA. Endovascular treatment strategies for coarctation of the aorta Thoracic Aortic Diseases. 2006:363-374. |
93. Vignon-Clementel IE, Figueroa CA, LaDisa J, Feinstein JA, Jansen KE, Taylor CA. Impedance outflow boundary conditions for three-dimensional patient specific modeling of blood flow Proceedings of the 2005 Summer Bioengineering Conference. 2005;2005:1444-1445. |
94. LaDisa JF, Olson LE, Guler I, Gross ER, Hettrick DA, Kersten JR, Warltier DC, Pagel PS. Coronary artery stent implantation alters wall shear stress during maximal vasodilation Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings. 2002;2:1228-1229. |
95. Ghorbannia A, Azarnoosh J, LaDisa JF Jr. Severity and duration-dependent aortic stiffening in a rabbit coarctation model identifies constitutive material parameters as promising regional biomarkers for hypertension progression. Sci Rep. 2026 Apr 14;16(1). PMCID: PMC13237106 |









