Medical College of Wisconsin
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CURRICULUM VITAE

Khyati Girdhar PhD
Assistant Professor
Department of Pediatrics
Division of Pediatrics Endocrinology

OFFICE ADDRESS:
8701 West Watertown Plank Road
Milwaukee, WI 53226
Phone: +1 (414) 9556745

EDUCATION:
07/2010 - 05/2013 BSc, HansRaj College, University of Delhi, Delhi, India
07/2013 - 06/2015 MSc, B. R. Ambedkar National Institute of Technology, Jalandhar, India
07/2015 - 08/2019 PhD, Indian Institute of Technology (IIT) Mandi, Mandi, India

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
09/2019 - 12/2019 Project Scientist, Biology, Indian Institute of Technology Mandi, Mandi, India
01/2020 - 10/2020 Postdoctoral Research Fellow, Internal Medicine, Endocrinology, University of Michigan, Ann Arbor, MI 48109
10/2020 - 12/2025 Postdoctoral Research Fellow, Biology, Boston College, Chestnut Hill, MA 02467

AWARDS AND HONORS:
2010 - 2015 Scholarship for Higher Education, Innovation in Science Pursuit for Inspired Research (INSPIRE)
2015 - 2019 Junior Research Fellowship, Council of Scientific & Industrial Research, India
2022 - 2023 D-Challenge Award, Sugar Science
2023 Boston College Postdoctoral Association Conference Travel Award, Boston College Postdoctoral Association
10/2024 - Present Boston College Travel Grant, Boston College
2024 Boston College Postdoctoral Association Conference Travel Award, Boston College Postdoctoral Association

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2011 - 2012 DSKC Internship Program, India (Volunteer)
2017 Salter’s Chemistry Camp (Volunteer )
2020 - 2022 Boston Postdoctoral Association (Volunteer)
2023 - 2024 Boston Postdoctoral Association (Co-Chair)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
2022 - 2024 Frontiers in Clinical Diabetes and Healthcare
2023 - Present Frontiers in Endocrinology

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Prior
Peer Review
Title:
D-Challenge Award
Source:
Sugar Science
Role & Effort:
33%
PI:
Emrah Altindis
Dates:
2022 - 2023
Direct Funds:
$30,000
  
Title:
Type-1 diabetes Research Grant
Source:
Diabetes Research Connection
Role & Effort:
100%
PI:
Khyati Girdhar
Dates:
2024 - 2025
Direct Funds:
$50,000
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
National
A Gut Microbial Peptide and Molecular Mimicry in the Pathogenesis of Type 1 Diabetes, MIT Microbiome Symposium, Cambridge, MA, 2022
A Gut Microbial Peptide and Molecular Mimicry in the Pathogenesis of Type 1 Diabetes, Boston College Biology Retreat, Portsmouth, NH, 2022
A human gut commensal, Parabacteroides distasonis, stimulates an inflammatory response specific to the pancreas but not to the intestines and induces Type 1 diabetes in NOD mice, American Diabetes Association Meeting, San Diego, CA, 2023
The impact of Parabacteroides distasonis colonization on hosts’ microbiome, metabolome, immune responses, and diabetes onset, Boston College, Biology Retreat, Waltham, MA, 2024
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
International
Rational Drug Design, Indo-Australia, Workshop, INDIA, 2019
High Content Screening, Workshop, IIT Mandi, India, 2019
 
National
Diversity, Equity, and Inclusion, Workshop, Boston College, MA, 2022
The Academic Life, Workshop, Boston College, MA, 2023
Biological Data Science Summer, Workshop, Virtual, 2023
Scientific Writing Retreat, Workshop, Cold Spring Harbor Laboratory, NY, USA, 2024
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Undergraduate Students
2020 - 2021 David Kim, Boston College
2020 - 2021 Tu Tran, Boston College
2020 - 2021 Scott Hsu, Boston College
2020 - 2022 Kaan Sevgi, Boston College
2020 - 2022 Maximilian Figura, Boston College
2020 - 2022 Amol Raisingani, Boston College
2022 - 2025 Alessandro Pezzella, Boston College
2022 Typhania Zanou, Boston College
2022 - 2023 Jaewon Oh, Boston College
2022 - 2025 Clarrisa Howard, Boston College
2023 - 2025 Maria Jove, Boston College
2023 - 2025 Lukas Rhodes, Boston College
 
Graduate Students
MS Students Advised
2017 - 2018 Swarnim Pandey, Synthesis of non-invasive dye for pancreatic beta cell imaging, Indian Institute of Technology Mandi,
2018 - 2019 Kriti Kochar, A mega stokes dye for detection of lipid droplets in live cells., Indian Institute of Technology (IIT) Mandi
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Girdhar, K., Mine, K., DaCosta, M.J., Atkinson, M., Ludvigsson, J., and Altindis, E., 2024. Sexspecific cytokine, chemokine, and growth factor signatures in T1D patients and progressors, The FASEB Journal, 38(24), p.e70270.
2. Girdhar, K., Randall, A.I., Dogru, Y.D., Howard, C., Pezzella, A., Henao, J., Gautam, U.K., ˆSaˆsinkov´a, P., Hudcovic, T., Schwarzer, M., Kiebish, M., and Altindis, E., 2024. The Impact of Parabacteroides distasonis Colonization on Hosts’ Microbiome, Metabolome, Immune Responses, and Diabetes Onset, bioRxiv, pp.2024-06.
3. Girdhar, K., Huang, Q., Dogru, Y.D., Yang, Y., Tolstikov, V., Chrudinova, M., Raisingani, A., Ludvigsson, J.F., Kiebish, M.A., Palm, N.W. and Ludvigsson, J., 2023. Dynamics of Gut Microbiome, IgA Response and Plasma Metabolome in Development of Pediatric Celiac Disease, Microbiome,11(1), pp.1-20.
4. Girdhar, K., Huang, Q., Chow, I.T., Vatanen, T., Brady, C., Raisingani, A., Autissier, P., Atkinson, M.A., Kwok, W.W., Kahn, C.R. and Altindis, E., 2022. A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes, Proceedings of the National Academy of Sciences, 119(31), p.e2120028119.
5. Girdhar, K., Thakur, S., Gaur, P., Choubey, A., Dogra, S., Dehury, B., Kumar, S., Biswas, B., Dwivedi, D.K., Ghosh, S. and Mondal, P., 2022. Design, synthesis, and biological evaluation of a small molecule oral agonist of the glucagonlike-peptide-1 receptor, Journal of Biological Chemistry, 298(5), p.101889.
6. Girdhar, K., Soto, M., Huang, Q., Orliaguet, L., Cederquist, C., Sundaresh, B., Hu, J., Figura, M., Raisingani, A., Canfora, E.E. and Dirice, E., Fujisaka, S., Goossens, G.H., Blaak, E.E., Kulkarni, R.N.,Kahn, C.R., Altindis, E., 2022. Gut Microbiota Regulate Pancreatic Growth, Exocrine Function, and Gut Hormones, Diabetes, 116919.
7. Girdhar, K., Dehury, B.,Singh, M.,Daniel, P., Choubey, A., Dogra, S., Kumar, S., Mondal, P., 2018. Novel insights into the dynamics behavior of Glucagon-Like Peptide-1 Receptor with its small molecule Agonists, Journal of Biomolecular Structure and Dynamics, 37(15), pp.3976-3986.
8. Sharma, R., Kumar, H., Singla, M., Kumar, V., Ansar, S. and Girdhar, K., 2022. Evolution of solute–solvent interactions for aqueous 1-decyl-3-methylimidazolium bromide,[C10mim][Br] solutions containing glycine/glycylglycine through volumetric and acoustic studies. Chemical Data Collections, 42, p.100963.
9. Mondal, I.C., Galkin, M., Sharma, S., Murugan, N.A., Yushchenko, D.A., Girdhar, K., Karmakar, A., Mondal, P., Gaur, P. and Ghosh, S., 2022. Organosulfur/Selenium-Based Highly Fluorogenic Molecular Probes for Live-Cell Nucleolus Imaging, Chemistry–An Asian Journal, 17(7), p.e202101281.
10. Kumar, H., Kumar, V., Sharma, S., Ghfar, A.A., Katal, A., Singla, M. and Girdhar, K., 2021. Thermophysical properties of amino acids L-serine and L-leucine in aqueous diammonium hydrogen phosphate solutions: volumetric and acoustic studies. Journal of Molecular Liquids, 344, p.117780.
11. Choubey, A., Girdhar, K., Kar, A.K., Kushwaha, S., Yadav, M.K., Ghosh, D. and Mondal, P., 2020. Low-dose naltrexone rescues inflammation and insulin resistance associated with hyperinsulinemia, Journal of Biological Chemistry, 295(48), pp.16359-16369.
12. Dogra, S.*, Kar, A.K.*, Girdhar, K.*, Daniel, P.V., Chatterjee, S., Choubey, A., Ghosh, S., Patnaik, S., Ghosh, D. and Mondal, P., 2019. Zinc oxide nanoparticles attenuate hepatic steatosis development in high-fat-diet fed mice through activated AMPK signaling axis, Nanomedicine: Nanotechnology, Biology and Medicine, 17, pp.210-222.
13. Biswas, B., Venkateswarulu, M., Sinha, S., Girdhar, K., Ghosh, S., Chatterjee, S., Mondal, P., Ghosh, S., 2019. Long Range Emissive Water-Soluble Fluorogenic Molecular Platform for Imaging Carbon Monoxide in Live Cells, ACS Applied Bio Materials, 2(12), pp.5427-5433.
14. Kumar, S., Ahmad, K., Tandon, G., Singh, U., Jha, Y., Nagrale, D., Singh, M., Girdhar, K., Mondal, P., 2018. Novel insight into the molecular interaction of catalase and sucrose: A combination of in silico and in planta assays study, Computers and Electronics in Agriculture, 151, pp.258-263.
 
Books, Chapters, and Reviews
1. Mondal, P., Prasad, A., Girdhar, K., 2017. Interventions to improve β-cell mass and function, Annales d’Endocrinologie, 29(25), 4445-4456.
2. Girdhar, K., Powis, A., Raisingani, A., Chrudinov´a, M., Huang, R., Tran, T., Sevgi, K., Dogus Dogru, Y. and Altindis, E., 2021. Viruses and Metabolism: The Effects of Viral Infections and Viral Insulins on Host Metabolism, Annual Review of Virology, 8, pp.373-391.
 
Patents
1. Khyati Girdhar, Pankaj Gaur, and Prosenjit Mondal, A non-peptidic Glucagon-Like Peptide-1 Receptor (GLP-1R) agonist for anti-obesity and anti-diabetes therapeutics, WO2020/110152 A1.