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CURRICULUM VITAE

Mandana Kamgar MD
Assistant Professor
Department of Medicine
Division of Hematology and Oncology - Medicine

OFFICE ADDRESS:
Froedtert Hospital
9200 W Wisconsin Ave
Milwaukee, WI 53226

EDUCATION:
02/2003 - 10/2010 MD, Tehran University of Medical Sciences, Theran, Iran
02/2007 - 08/2010 MPH, Tehran University of Medical Sciences, Tehran, Iran

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/2011 - 06/2013 Research Fellowship, Department of Internal Medicine, Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA
07/2013 - 06/2016 Internal Medicine Residency, Department of Internal Medicine, John Stroger Jr. Hospital of Cook County, Chicago, IL
07/2016 - 06/2019 Hematology and Oncology Fellowship, Department of Internal Medicine, Division of Hematology and Oncology, Karmanos Cancer Center/Wayne State University, Detroit, MI

FACULTY APPOINTMENTS:
08/01/2019 - Present Assistant Professor, Medicine, Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI
08/01/2020 - Present Assistant Professor, Surgery, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
2019 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Internal Medicine
2016
2026
Medical Oncology
2019
2029
Hematology
2019
2029
 
Licensure
Number Issue DateExpiration
Chicago License
125063676
2013
2016
Michigan License
301109657
2016
2019
Wisconsin License
70759
2019
2021
 

AWARDS AND HONORS:
2012 - Present Young Investigator Award, American Society of Transplantation

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2017 - Present American Society of Clinical Oncology
2019 - Present The Alliance for Clinical Trials in Oncology (GI Committee Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
11/25/2019 - Present BMC Cancer
Ad-Hoc Reviewer
03/2020 - 04/2020 External Reviewer of a proposal submitted to the CTSA External Reviewers Exchange Consortium (CEREC)
10/06/2020 - Present Cancer and Metastasis Reviews
11/08/2020 - Present Scientific Reports
11/2020 - Present Reviewer for grant applications to Advancing a Healthier Wisconsin (AHW’s) Basic, Clinical, and Translational Research Pathway

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Role of a Patient Derived Explant Model in prediction of response to standard chemotherapy in patients with metastatic pancreatic ductal adenocarcinoma
Role:
Co-Investigator
PI:
Marja T Nevalainen, MD, PhD
 
Title:
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine Treatment (NAPOLI 3)
Role:
Institutional Principal Investigator
 
Title:
Title: An Investigator-Sponsored Phase Ib Study of the Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330), Gemcitabine and nab-Paclitaxel and Phase II Study of Gemcitabine and Selinexor in Patients with Metastatic Pancreatic Cancer
Role:
Institutional Principal Investigator
PI:
Philip A Philip
 
Title:
Serial Blood Profiling for Micro-RNA Expression Signatures to Gemcitabine/Nab-Paclitaxel in Pancreatic Ductal Adenocarcinoma Patients.
Role:
Lead Investigator
PI:
Asfar S Azmi
 
Title:
HRI-AX-CL-PANC-PI-13301 / Nab-Paclitaxel + Cisplatin + Gemcitabine in Untreated Metastatic Pancreatic Adenocarcinoma
Role:
Institutional Principal Investigator
PI:
Gayle Jameson, ACNP-BC
 
Pending
Non-Peer Review
Title:
Phase I dose escalation of CPI-613 along with chemoraidation in patients with pancreatic adenocarcinoma in need of definitive local control
Role:
Principal Investogator
 
Title:
A Phase II Study of Adjuvant Metformin/Doxycycline/Mebendazole/Atorvastatin in Patients with Resected Pancreatic Ductal Adenocarcinoma and Elevated Post-treatment CA 19-9
Role:
Principal Investigator
PI:
Mandana Kamgar, MD, MPH; Kathleen Christians, MD
 
Prior
Peer Review
Title:
A Phase 2 Study of Gemcitabine plus BPM31510 (Ubidecarenone, USP) Nanosuspension Injection Administered Intravenously as 2nd line therapy in Advanced Pancreatic Cancer Patients
Role:
Institutional Principal Investigator
Dates:
12/10/2019 - Present
 
Title:
Comprehensive genomic profiling in metastatic pancreatic adenocarcinoma, correlation with early death versus prolonged survival
Role:
Principle Investigator
PI:
Mandana Kamgar, MD, MPH, Mohammed Najeeb Al-Hallak, MD, MS
 
Title:
PAK4-NAMPT Dual Inhibition for Therapy Resistant Pancreatic Neuroendocrine Tumors
Role:
Co-Investigator
PI:
Asfar S Azmi
 
Title:
Clinical Translation of Nuclear Export Inhibitor-Gemcitabine-Nab-Paclitaxel in Pancreatic Ductal Adenocarcinoma
Role:
Co-Investigator
PI:
Philip A Philip
 
Title:
Role of Calcium release-activated calcium (CRAC) channel inhibition in pancreatic ductal adenocarcinoma
Role:
Co-Investigator
PI:
Asfar S Azmi
 
Title:
Long Term Peripheral neuropathy in Breast Cancer Survivors, an Analysis of Data from the Women Health Initiative’s Life and Longevity after Cancer (LILAC) Data Base.
Role:
Lead Investigator
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Comprehensive molecular profiling of patients with pancreatic adenocarcinoma: A single institution’s experience, Molecular Tumor Board, Karmanos Cancer Institute, Detroit, 2018
Precision Medicine for Pancreatic Cancer, MCW 2020 Surgical Oncology Symposium, Virtual, 10/23/2020
GI ASCO Update, 10th Annual MCW Pancreatic Cancer Virtual Symposium, Virtual, 01/22/2021
ASCO Updates and Current Metastatic Clinical Trials, 2021 ASCO Pancreatic Cancer Review & Clinical Trials at MCW, Virtual, 06/21/2021
 
National
Mandana Kamgar, Hadeel Assad, Theresa A. Hastert, Eric McLaughlin, Kerryn Reding, Electra D. Paskett, Jennifer W. Bea, Aladdin H. Shadyab, Marian L. Neuhouser, Rami Nassir, Tracy E. Crane, Kalyan Sreeram, Mark K. Greenwald, Michael S. Simon, Peripheral Neuropathy after Breast Cancer: An Analysis of Data from the Women’s Health Initiative Life and Longevity After Cancer Cohort, Women’s Health Initiative Life and Longevity After Cancer (WHI LILAC) Webinar, Virtual, 04/27/2020
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Community/Lay Public
11/11/2020 - Present "Metastatic Treatment and HRI-AX-CL Trial" session as part of Pancreatic Cancer Awareness lecture series
12/02/2020 Lecture titled "Understanding Pancreatic Cancer" as part of "My Health Classes" for the community
 
Resident and Fellow Education
05/13/2020 - Present Non-colorectal Gastrointestinal (GI) Oncology for Internal Medicine Board
10/27/2020 - Present Lecture titled "Pancreatic Ductal Adenocarcinoma (PDAC), Diagnosis and Management" was presented to Hematology/Oncology fellows as part of their educational GI oncology lectures
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Kamgar M, Greenwald MK, Assad H, Hastert TA, McLaughlin EM, Reding KW, Paskett ED, Bea JW, Shadyab AH, Neuhouser ML, Nassir R, Crane TE, Sreeram K, Simon MS. Prevalence and predictors of peripheral neuropathy after breast cancer treatment. Cancer Med. 2021 Oct;10(19):6666-6676. PMCID: PMC8495292
2. Kim RY, Christians KK, Aldakkak M, Clarke CN, George B, Kamgar M, Khan AH, Kulkarni N, Hall WA, Erickson BA, Evans DB, Tsai S. Total Neoadjuvant Therapy for Operable Pancreatic Cancer. Ann Surg Oncol. 2021 Apr;28(4):2246-2256.
3. Krepline AN, Geurts JL, George B, Kamgar M, Madhavan S, Erickson BA, Hall WA, Griffin MO, Evans DB, Tsai S, Kim RY. Cost-effectiveness analysis of universal germline testing for patients with pancreatic cancer. Surgery. 2021 03;169(3):629-635.
4. Barnes CA, Aldakkak M, Christians KK, Clarke CN, Dua K, George B, Ritch PS, Kamgar M, Hall WA, Kulkarni N, Erickson BA, Evans DB, Tsai S. Radiographic patterns of first disease recurrence after neoadjuvant therapy and surgery for patients with resectable and borderline resectable pancreatic cancer. Surgery. 2020 09;168(3):440-447.
5. Khan HY, Mpilla GB, Sexton R, Viswanadha S, Penmetsa KV, Aboukameel A, Diab M, Kamgar M, Al-Hallak MN, Szlaczky M, Tesfaye A, Kim S, Philip PA, Mohammad RM, Azmi AS. Calcium Release-Activated Calcium (CRAC) Channel Inhibition Suppresses Pancreatic Ductal Adenocarcinoma Cell Proliferation and Patient-Derived Tumor Growth. Cancers (Basel). 2020 Mar 22;12(3). PMCID: PMC7140111
6. AN Krepline, JL Geurts, B George, M Kamgar, S Madhavan, BA Erickson, WA Hall, MO Griffin, DB Evans, S Tsai, RY Kim. Cost-effectiveness analysis of universal germline testing for patients with pancreatic cancer Surgery. 169 (3), 629-635.
7. Preclinical assessment with clinical validation of Selinexor with gemcitabine and nab-paclitaxel for the treatment of pancreatic ductal adenocarcinoma. (Azmi AS, Khan HY, Muqbil I, Aboukameel A, Neggers JE, Daelemans D, Mahipal A, Dyson G, Kamgar M, Al Hallak MN, Tesfaye A, Kim S, Shidham V, Ramzi M, Philip PA) Clin Cancer Res 2019 Dec 12 PMID: 31831564 12/14/2019
8. Mpilla G, Aboukameel A, Muqbil I, Kim S, Beydoun R, Philip PA, Mohammad RM, Kamgar M, Shidham V, Senapedis W, Baloglu E, Li J, Dyson G, Xue Y, El-Rayes B, Azmi AS. PAK4-NAMPT Dual Inhibition as a Novel Strategy for Therapy Resistant Pancreatic Neuroendocrine Tumors. Cancers (Basel). 2019 Nov 29;11(12). PMCID: PMC6966587
 
Books, Chapters, and Reviews
1. Hall WA, Kamgar M, Erickson BA, Ponce SB, Tsai S, Nevalainen MT, Christians KK, George B, Dua KS, Khan AH, Evans DB, Azmi AS. Updates and new directions in the use of radiation therapy for the treatment of pancreatic adenocarcinoma: dose, sensitization, and novel technology. Cancer Metastasis Rev. 2021 Sep;40(3):879-889.
2. Kamgar M, Chakrabarti S, Shreenivas A, George B. Evolution of Systemic Therapy in Metastatic Pancreatic Ductal Adenocarcinoma. Surg Oncol Clin N Am. 2021 Oct;30(4):673-691.
3. Chakrabarti S, Kamgar M, Mahipal A. Targeted Therapies in Advanced Biliary Tract Cancer: An Evolving Paradigm. Cancers (Basel). 2020 Jul 24;12(8). PMCID: PMC7465131
4. Philip PA, Kamgar M (2019).'How I Treat Resectable Pancreatic Cancer With Adjuvant Therapy', in T Bekaii-Saab, B El-Rayes, T Pawlik (ed.) Handbook of Gastrointestinal Cancers: Evidence-Based Treatment and Multidisciplinary Patient Care: "Springer Publishing" 183-190
5. Al-Qambar B, Chaker M, Kamgar M, Tesfaye A, Uwe-Wagner K, Azmi AS. Protocols in genetic mice models of pancreatic cancer Animal Models in Cancer Drug Discovery. 17 April 2019:107-123.
6. Tesfaye AA, Kamgar M, Azmi A, Philip PA. The evolution into personalized therapies in pancreatic ductal adenocarcinoma: challenges and opportunities. Expert Rev Anticancer Ther. 2018 02;18(2):131-148. PMCID: PMC6121777
7. Jamali A, Kamgar M, Massarrat S, Sotoudeh M, Larijani B, Adler G, Seufferlein T. Pancreatic Cancer: State of the Art and Current Situation in the Islamic Republic of Iran Govaresh. 2009;14(3):189-197.
 
Editorials, Letters to Editor, Other
1. Evans DB, Kamgar M, Tsai S. Goals of Treatment Sequencing for Localized Pancreatic Cancer. Ann Surg Oncol. 2019 Nov;26(12):3815-3819.