Faculty Collaboration Database -

CURRICULUM VITAE

Mary F. Otterson MD, MS

Emeritus Professor
Department of Surgery
Division of Surgery Colorectal


OFFICE ADDRESS:
Remote-Exception
Remote Location
Madison, WI 53702


EDUCATION:
1973 - 1974 Marquette University, Milwaukee, WI
1975 - 1976 Student Trainee, Harkness House for Ballet Arts, New York, NY
1976 - 1980 BS - Clinical Dietetics, Chemistry, Mount Mary College, Milwaukee, WI
1980 - 1984 MD, Medical College of Wisconsin, Milwaukee, WI
1987 - 1988 MS - Physiology, Medical College of Wisconsin, Milwaukee, WI


POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
1984 - 1990 Resident, General Surgery, Medical College of Wisconsin, Milwaukee, WI
01/1988 - 07/1988 Registrar, General Surgery, Oxford University, Oxford, England


FACULTY APPOINTMENTS:
1990 - 1996 Assistant Professor, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI
1990 - 1995 Assistant Professor, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI
1995 - 2004 Associate Professor, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI
1996 - Present Associate Professor, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI
2004 - Present Professor, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI
2005 - Present Tenure, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI


ADMINISTRATIVE APPOINTMENTS:
2002 - 2006 Vice Chairman of Surgery, Medical College of Wisconsin, Milwaukee, WI
2002 - 2006 Chief of Surgery, Zablocki Veteran’s Affairs Center, Milwaukee, WI


EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
1990 - 2000 Advanced Trauma Life Support Instructor
1997 - 2000 Research Honors Committee
1999 - Present Alpha Omega Alpha, Medical Honor Society, Medical College of Wisconsin, Milwaukee, WI
1999 - 2002 Chair, Academic and Student Affairs, Mount Mary College, Milwaukee, WI
1999 - Present Research Committee, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI
2000 - Present Medical Scientist Training Program
2002 - 2004 Resident Education Committee


HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
1990 - Present Zablocki Veteran’s Affairs Center, 5000 W. National Avenue, Milwaukee, WI 53295
1990 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Avenue, Milwaukee, WI
1990 - 1995 John L. Doyne Hospital, Milwaukee, WI
1994 - 1995 Medical Staff Secretary, John L. Doyne Hospital, Milwaukee, WI
1997 - 1999 Clinical Practice Standards Committee, Froedtert Memorial Lutheran Hospital, Milwaukee, WI


HOSPITAL STAFF PRIVILEGES:
1990 - Present Froedtert Memorial Lutheran Hospital, Milwaukee, WI
1990 - Present Zablocki Veteran’s Affairs Medical Center, Milwaukee, WI


SPECIALTY BOARDS AND CERTIFICATION:


Board Certified	Issue Date	Expiration
American Board of Surgery	05/1991	07/2021


Licensure	Number	Issue Date	Expiration
Wisconsin License	27051	10/31/2007	10/31/2011


AWARDS AND HONORS:
1984 Award of Clinical Proficiency, Medical College of Wisconsin
1984 Outstanding Student of the Year in Surgery, Medical College of Wisconsin
1984 J.C. Peterson Pediatrics Award, Medical College of Wisconsin
1984 Hofmeister Award, Gynecology and Obstetrics, MCW
1984 American Medical Women’s Association Citation, Medical College of Wisconsin
1984 Alpha Omega Alpha
1989 - 1990 Administrative Chief Surgical Resident, Medical College of Wisconsin
1989 - 1990 Resident Research Award, Milwaukee Academy of Surgery
1989 - 1990 Student Research Prize, American Gastroenterological Association
1993 Madonna Medal for Professional Excellence, Mount Mary College, Milwaukee WI
1999 Janssens Award, Research in Digestive Diseases
1999 - 2013 Best Doctors in America
2004 America’s Top Surgeons
2004 - 2005 Executive Leadership in Academic Medicine (ELAM)
2007 Top 20 Physicians at Froedtert Hospital
2008 - 2015 Milwaukee’s Top Doctors, Milwaukee Magazine
2008 Madison’s Who’s Who
2010 Top 20 Physicians at Froedtert Hospital


MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1987 Association for Academic Surgery (Member)
1989 American Physiology Society (Member)
1989 American Motility Society (Member)
1990 Collegium Internationale Chirurgiae Digestivae (Member)
1990 Milwaukee Gastroenterological Society (Member)
1991 American Gastroenterological Association (Member)
1993 American College of Surgeons (Fellow)
1994 Association of Women Surgeons (Member)
1994 Wisconsin Surgical Society (Member)
1995 Society for Surgery of the Alimentary Tract (Member)
1995 Central Surgical Society (Member)
1995 Surgical Biology Club III, American College of Surgeons (Member)
1996 Society of University Surgeons (Member)
1998 Association of VA Surgeons (Member)
1999 - 2001 Milwaukee GI Society (President)
1999 Milwaukee Academy of Surgery (Member)
2006 - 2007 Wisconsin Surgical Society, a chapter of the American College of Surgeons (President)
2010 American Surgical Association (Member)


EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
World Journal of Gastrointestinal Pathophysiology


LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1979 Chairperson, Clinical Dietetics and Research, Wisconsin Dietetic Association
1996 - 1998 Secretary – Treasurer, Milwaukee Gastroenterological Society
1996 - 1997 Member, Policy and Planning Committee, Wisconsin Surgical Society
1998 Member, Auditing Committee, Central Surgical Association
1998 - Present Member, Research Review Committee, Digestive Disease
2002 Member, Auditing Committee, Central Surgical Association
2002 - 2005 Secretary, Wisconsin Surgical Society
2003 - 2005 Secretary Treasurer, Wisconsin Surgical Society
2003 - 2007 Member, Program Committee, Central Surgical Association
2006 - 2007 President, A chapter of the American College of Surgeons, Wisconsin Surgical Society
2007 - 2009 Councilor, Central Surgical Association


NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1991 - 1993 Member, Planning Committee, Little Brain-Big Brain III
1992 - 1994 Member, Nominating Committee, AGA, Motility and Nerve-Gut Interactions
1992 - 1993 Member, AGA, Digestive Disease Week Abstract Selection
1992 - 1994 Member, Nominating Committee, American Motility Society
1993 Chairman, Abstract Selection Committee, Digestive Diseases Week
1993 - 1995 Member, Membership Committee, Association for Academic Surgery
1994 - 1998 Councilor, American Motility Society
1994 Ad Hoc Reviewer, Veteran Affairs Merit Review Program
1995 Ad Hoc Reviewer, NIDDK, GMA
1995 Member, Membership Steering Committee, Motility and Nerve-Gut Interactions, AGA
1995 - 1997 Councilor, AGA, Motility and Nerve-Gut Interactions
1996 Member, Ad Hoc Meeting Committee, Central Surgical Association
1997 Ad Hoc Reviewer, Veteran Affairs Merit Review Program
1999 - 2001 Member, Planning Committee, Little Brain-Big Brain VII
1999 Ad Hoc Reviewer, NIDDK, GMA-2
2000 - 2003 Member, Membership Committee, Association of VA Surgeons
2000 - 2005 Examination Consultant, In-Training/Surgical Basic Science Examination Committee, American Board of Surgery
2001 - 2004 Member, Committee on Women in Gastroenterology, AGA
2002 - 2003 Member, Planning Committee, Little Brain-Big Brain VII
2003 Ad Hoc Reviewer, NIH RO3 Study Section
2004 Ad Hoc Reviewer, NIH ZRG1 Study Section
2005 Ad Hoc Reviewer, Special Emphasis Review Panel (PAR 04-082)
05/06/2010 Ad Hoc Reviewer, Radiation/Nuclear Medical Countermeasure Product Development Support Services, Special Emphasis Review Panel
2010 - 2012 Member, Awards Committee, Association of VA Surgeons
2011 - 2016 Member, Rad-Nuc Data Monitoring Committee, DAIT, NIAID
2011 - 2015 Member, Research Committee, Society for Surgery of the Alimentary Tract

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:


Active
Non-Peer Review
Title:	Gastric Emptying in Conscious Dogs: Motility Effects of Grehlin Analogs
Source:	GSK Pharmaceuticals
Role & Effort:	Principal Investigator
PI:	Self
Dates:	02/01/2006 - Present
Direct Funds:	$168,000


Prior
Peer Review
Title:	Effects of Fractionated Irradiation on Small Intestinal Motility
Source:	Medical College of Wisconsin Cancer Center
Role & Effort:	Co-Principal Investigator
Dates:	07/01/1987 - 06/30/1988
Direct Funds:	$7,000

Title:	Effect of Radiation on Enteric Neuroregulatory Mechanisms
Source:	Medical College of Wisconsin Cancer Center
Role & Effort:	Principal Investigator
PI:	Self
Dates:	07/01/1990 - 06/30/1991
Direct Funds:	$7,471

Title:	Gastrointestinal Motor Effects of Ionizing Radiation
Source:	NIH - FIRST Award
Role & Effort:	Principal Investigator, 50% of effort
PI:	Self
Dates:	07/01/1990 - 06/30/1995
Direct Funds:	$339,704

Title:	Control of Gastrointestinal Motility in Health and Disease
Source:	VA Merit Review
Role & Effort:	Co-investigator, 10% of VA effort
Dates:	07/01/1992 - 06/30/1995
Direct Funds:	$257,300

Title:	Feasibility of Cryotherapy for the Treatment of Human Breast Cancer: Analysis in a Large Animal Model
Source:	Medical College of Wisconsin Cancer Center
Role & Effort:	Co-investigator
Dates:	07/01/1995 - 06/30/1996
Direct Funds:	$10,000

Title:	The Role of Nitric Oxide on Radiation Induced Small Intestinal Contractions
Source:	Medical College of Wisconsin Cancer Center
Role & Effort:	Principal Investigator
PI:	Self
Dates:	01/01/1997 - 12/31/1997
Direct Funds:	$10,000

Title:	Gastrointestinal Motor Effects of Ionizing Radiation
Source:	NIH - RO1
Role & Effort:	Principal Investigator, 30% of effort
PI:	Self
Dates:	08/01/1997 - 06/30/2001
Direct Funds:	$422,283

Title:	Immunomodulation of Breast Cancer Using Cryo- and Dendritic Cell Therapy
Source:	Medical College of Wisconsin Cancer Center
Role & Effort:	Co-Principal Investigator
Dates:	07/01/1999 - 06/30/2000
Direct Funds:	$17,500

Title:	Human Intestinal Microvascular Endothelial Cells in Radiation Enteritis
Source:	Digestive Disease Center of the Medical College of Wisconsin
Role & Effort:	Principal Investigator
PI:	Self
Dates:	07/01/2000 - 06/30/2002
Direct Funds:	$25,000

Title:	The Effect of Ionizing Radiation on Human Intestinal Microvascular Endothelial Cells (HIMEC): An Anti-angiogenic Mechanism in Colorectal Adenocarcinoma Therapy
Source:	Medical College of Wisconsin Cancer Center
Role & Effort:	Co-Investigator
Dates:	07/01/2000 - 06/30/2001
Direct Funds:	$25,000

Title:	Work Conditions of Surgery Residents and Quality of Care
Source:	American College of Surgeons
Role & Effort:	Site Principal Investigator, Current site response rate - > 90%
Dates:	05/01/2003 - 04/30/2005

Title:	Chloraprep vs Betadine for Prevention of Infection of Clean-Contaminated Surgical Wounds: a Prospective, Randomized, Multicenter Clinical Trial
Source:	Mediflex
Role & Effort:	Site Principal Investigator
PI:	Self
Dates:	05/01/2004 - 04/30/2008

Title:	Mesh Repair of Ventral Hernia: Which Rate is Right?
Source:	Department of Veteran Affairs
Role & Effort:	Site Principal Investigator
PI:	Self
Dates:	10/01/2004 - 10/01/2006

Title:	Post-Irradiation Intervention to Mitigate and Treat Non-Hematological Injuries
Source:	NIH Center for Medical Countermeasures against Radiation
Role & Effort:	Project Leader, 25% of effort Post Irradiation Modulation of Gastrointestinal Injury, Associate Center Director, 5% of effort
Dates:	08/31/2005 - 07/31/2010
Direct Funds:	$13,362,166

Title:	Percutaneous Colostomy for Bowel Management in Spinal Cord Injury
Source:	Veteran Affairs Rehabilitation Merit Review
Role & Effort:	Principal Investigator, 10% of effort
PI:	Self
Dates:	05/01/2006 - 04/30/2009
Direct Funds:	$380,100

Title:	Intestinal Alkaline Phosphatase is a Mitigator of the Acute Radiation Syndrome
Source:	Digestive Disease Center of the Medical College of Wisconsin
Role & Effort:	Principal Investigator
PI:	Self
Dates:	09/15/2013 - 09/15/2014
Direct Funds:	$12,000

Non-Peer Review
Title:	Efficacy of the Overfill Technique to Treat Withdrawal Occlusion in Central Venous Catheters using Urokinase
Source:	Abbott Laboratories
Role & Effort:	Principal Investigator
PI:	Self
Dates:	03/15/1997 - 04/30/1999
Direct Funds:	$34,059

Title:	Motility Effects of RWJ-68023
Source:	R.W. Johnson Pharmaceutical Research Institute
Role & Effort:	Principal Investigator
PI:	Self
Dates:	01/01/2000 - 12/31/2002
Direct Funds:	$41,000 (Date Renewed: May, 2001Direct Funds: $91,800)

Title:	Treatment of Breast Cancer Using Cryo- and Dendritic Cell Therapy
Source:	Alvin and Marion Birnschein Foundation, Inc.
Role & Effort:	Principal Investigator
PI:	Self
Dates:	01/01/2000 - 12/31/2001
Direct Funds:	$15,000 ($15,000/year)

Title:	The Role of Nutritive and Non-nutritive Food Additives on Gastrointestinal Motility in the Dog
Source:	Depomed Inc.
Role & Effort:	Principal Investigator
PI:	Self
Dates:	05/01/2000 - 04/30/2001
Direct Funds:	$35,000

Title:	Motility Effects of Cisapride Analogs
Source:	Aryx Pharmaceuticals
Role & Effort:	Principal Investigator
PI:	Self
Dates:	03/12/2003 - 12/31/2004
Direct Funds:	$91,850 (December, 2003 $129,850)

Title:	Motility Effects of Cisapride Analogs
Source:	Aryx Pharmaceuticals
Role & Effort:	Principal Investigator
PI:	Self
Dates:	03/12/2003 - 12/31/2004
Direct Funds:	$129,850

Title:	Injury and Response of PMHS due to Chest Impact
Source:	Titan Corporation
Role & Effort:	Co Investigator
Dates:	02/01/2006 - 01/31/2006


INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
International
Effects of Ionizing Radiation of Small Bowel Motility, Research Seminar, Nuffield Department of Surgery, Oxford University, Oxford, England, 02/05/1988
Ionizing Radiation and Small Intestinal Motility, University Radiotherapy Research Seminar, Oxford University, Oxford, England, 06/15/1988
Motor Effects of Ionizing Radiation on the Small Intestine, Physiology Research Seminar, London, England, 06/17/1988
Enteric Neural Control of Giant Migrating Contractions, Young Investigators Conference, Munich, Germany, 09/07/1989
Enteric Neural Control of Giant Migrating Contractions, International Symposium on Gastrointestinal Motility, Gmunden, Austria, 09/12/1989
Fractionated Doses of Radiation alter Enteric Neuroregulatory Peptides, Little Brain - Big Brain II, Kobe, Japan, 11/14/1991
Giant Migrating Contractions Following Surgical Transection of the Bowel, Collegium Internationale Chirurigae Digestive, Athens, Greece, 09/22/1992
Small Intestine, Collegium Internationale Chirurigae Digestivae, Athens, Greece, 09/22/1992
Interruption of Ileal Myenteric Plexus Alters the Colonic Motor Response to Irradiation, Little Brain - Big Brain III, Toronto, Canada, 08/1993
The Role of Intraluminal Bile on Small Intestinal Contractions Produced by Irradiation, Little Brain - Big Brain IV, Munich, Germany, 10/31/1995
The NK1 Receptor Modifies the Colonic Contractile Response to Radiation, Little Brain - Big Brain VI, Belgium, 10/31/1999
Multivariate Analysis Suggests that Peri-operative Crohn’s Disease Intra-abdominal septic complications are Decreased by Concomitant Immunomodulator Therapy, Central Surgical Association Meeting, Toronto, Canada, 03/2003
Genetic Influences of Late Colonic Motility Changes Induced by Ionizing Radiation, Little Brain - Big Brain VII, Barcelona, Spain, 10/03/2003
Surgical Management of Crohn’s Disease, Alberta Heritage Foundation Visiting Scholar, University of Calgary, Calgary, Alberta, Canada, 10/2004
Radiation Motility Effects on the Gastrointestinal Tract, Alberta Heritage Foundation Visiting Scholar, University of Calgary, Calgary, Alberta, Canada, 10/2004

National
Gastrointestinal Side Effects of Erythromycin, Residents' Conference, Society of University Surgeons, San Antonio, TX, 02/10/1988
ENS Effect of Substance P on Colonic Motor Activity in the Conscious and Anesthetized States and During Laparotomy, American Motility Society Meeting, Asilomar, CA, 10/04/1988
Comparison of Gastrointestinal Side Effects of Erythromycin, Roxithromycin and Clarithromycin, FASEB, New Orleans, LA, 03/22/1989
Alterations in Small Intestinal Contractions Following Surgical Transection and Anastomosis, Residents' Conference, Society of University Surgeons, Los Angeles, CA, 02/10/1990
Small Intestinal Contractions Associated with Vomiting Following Transection of the Gut, FASEB, Anaheim, CA, 04/08/1992
Small Intestinal Motility, American Gastroenterological Association, San Francisco, CA, 05/12/1992
NO NANC Nerves Modulate Migrating Motor Complexes (MMCs) and Postprandial State, American Motility Society, Lake Tahoe, NV, 09/14/1992
Radiation Effects on GI Motility and Potential Therapies, Second Consensus Development Conference on the Treatment of Radiation Injuries, Bethesda, MD, 04/14/1993 - 04/17/1993
Clinical Motility of the Small Intestine, American Gastroenterological Association, Boston, MA, 05/19/1993
Paradoxical Inhibition of Motor Activity in the Human Cecum and Appendix after a Meal is Mediated by Cholinergic Nerves, American Gastroenterological Association, Boston, MA, 05/19/1993
Small Intestinal Motility, American Gastroenterological Association, New Orleans, LA, 05/16/1994
Central NK1 Receptors Mediate Radiation Induced Emesis, American Gastroenterological Association, Washington, DC, 05/14/1997
Balancing Family and Career, American Gastroenterological Association, AGA Women’s Committee,, New Orleans, LA, 05/19/1998
Cryo-Dendritic Cell Therapy Improves the Response to Breast Carcinoma in BALBc Model, Association of VA Surgeons, Seattle, WA, 04/2000
Long-term Neurochemical and Motility Adaptations Associated with Irradiation, American Gastroenterological Association, Atlanta, GA, 05/2001
Surgery and the Patient with Ehlers – Danlos Syndrome, Eleventh Annual Ehlers –Danlos Learning Conference, Milwaukee, WI, 07/19/2001
Obstacles to Leadership for Women in Surgery, Association for Academic Surgery, Milwaukee, WI, 11/15/2001
Acetazolamide Decreases Post-Laparoscopy Pain but not Post-Operative Nausea and Vomiting, Association of VA Surgeons, Nashville, TN, 04/2002
Crohn’s Disease Update, Gastrointestinal Disease Course, 88th Annual Clinical Congress of the American College of Surgeons, San Francisco, CA, 10/07/2002 - 10/08/2002
Radiographic Underestimation of Small Bowel Stricturing Crohn’s Disease: A Comparison with Surgical Findings, 61st Annual Meeting of the Central Surgical Association, 03/05/2004
Colonic Motility, Annual Clinical Congress SAGES, 04/02/2004
Multi-disciplinary Approach to Improve Patients Outcomes in Crohn's Disease, 91th Annual Clinical Congress of the American College of Surgeons, San Francisco, CA, 10/2005
Tips for New NIH Grant Applicants, 4th Annual Choosing a Career is Academic Gastroenterology and Hepatology, AGA symposium, Milwaukee, WI, 10/2007
Canine Animal Models, Public Workshop on Animal Models for the Treatment of Acute Radiation Syndrome (ARS),, 09/17/2008 - 09/18/2008
Post-Irradiation Modulation of Gastrointestinal Injury, NIAID Gastrointestinal Acute Radiation Syndrome Meeting, Rockville, MD, 02/02/2009 - 02/03/2009
Writing a Gran, 5th Annual Choosing a Career is Academic Gastroenterology and Hepatology, Milwaukee, Wisconsin, 10/2009
What You Should Know to Prepare Your Patients for GI-Related Surgeries: a Surgeon’s Perspective, AGA, Orlando, FL, 05/21/2013

Regional
How to Protect Your Research Time, 89th Annual Clinical Congress of the American College of Surgeons, Chicago. IL, 10/21/2003
Insides Out: Your Answers to Surgery, Ostomy Issues, and Living with IBD, CCFA 14th Annual Family and Patient Education Conference, Chicago, IL, 04/04/2009

Local
Therapeutic Doses of Ionizing Radiation Induce Giant Migrating Contractions of the Small Intestine, Wisconsin Surgical Society Resident Program, Woodruff, WI, 09/18/1987
Etiology of the Gastrointestinal Side Effects of Therapeutic Doses of Ionizing Radiation, Thesis Presentation, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, 12/23/1987
Etiology of Gastrointestinal Side Effects of Erythromycin, Wisconsin Surgical Society Resident Program, Lake Geneva, WI, 09/16/1988
Effects of Ionizing Radiation on Small Intestinal Motor Activity, Milwaukee Academy of Surgery, Milwaukee, WI, 03/27/1989
Effect of Surgical Transection on Small Intestinal Contractions, Milwaukee Academy of Surgery, Milwaukee, WI, 03/26/1990
Fractionated Irradiation alters Enteric Neuroendocrine Products, Diseases Research Seminar, Milwaukee, WI, 02/20/1992
Preparing for Medical School, Women in Science Career Workshop, Milwaukee, WI, 03/25/1992
Therapeutic Radiation Alters Enteric Neuroregulatory Peptides, Wisconsin Surgical Society Program, Milwaukee, WI, 04/25/1992
Diagnostic Dilemmas-Barium and Capsule Endoscopy, Wisconsin Chapter CCFA, Difficult Decisions in Inflammatory Bowel Disease, Wisconsin Dells, WI, 03/27/2004
Managing Pregnancy in IBD, Wisconsin Chapter CCFA, Difficult Decisions in Inflammatory Bowel Disease, Wisconsin Dells, WI, 03/27/2004
Writing a Grant, 5th Annual Choosing a Career is Academic Gastroenterology and Hepatology, AGA symposium, Milwaukee, WI, 10/2009
Surgical Infections, Lake Effect interview, WUWM, National Public Radio affiliate, Southeastern, WI, 02/01/2010


COMMITTEE SERVICE:
Medical College of Wisconsin
1991 Member, Five Year Intramural Review, Division of Surgery, Medical College of Wisconsin
1991 Member, Clinical Research Center, NIH Site Visit, Medical College of Wisconsin
1991 - 1998 Member, Steering Committee, Digestive Diseases Research Center, Medical College of Wisconsin
1995 Member, Institutional Strategic Plan Research Task Force, Medical College of Wisconsin
1996 Member, Five Year Intramural Review, Division of Anesthesiology, Medical College of Wisconsin
1997 - 2000 Member, Research Honors Committee, Medical College of Wisconsin
1998 - Present Member, Research Committee, Department of Surgery, Medical College of Wisconsin
1999 Member, GI Malignancy & Surveillance Committees, Inflammatory Bowel Diseases Program, Medical College of Wisconsin
1999 - 2002 Chair, Academic and Student Affairs, Mount Mary College
1999 - Present Member, Research Committee, Department of Surgery, Member
1999 Member, Alpha Omega Alpha, Medical Honor Society, Medical College of Wisconsin
1999 - 2003 Member, Women’s Faculty Council, Medical College of Wisconsin
1999 Co-Chairman, Lower-GI Motility/Function Bowel Disorders, Digestive Disease Center, Medical College of Wisconsin
1999 Member, Selection Committee, Alpha Omega Alpha, Medical Honor Society, Medical College of Wisconsin
2000 Member, Admissions Committee, Medical Scientist Training Program, Medical College of Wisconsin
2000 Secretary, Women’s Faculty Council, Medical College of Wisconsin
2001 Chairman, Search Committee, Plastic and Reconstructive Surgery, Medical College of Wisconsin
2002 President, Women’s Faculty Council, Medical College of Wisconsin
2002 - 2004 Member, Resident Education Committee, Medical College of Wisconsin
2002 - 2003 Chairman, Search Committee, Cardiothoracic Surgery, Medical College of Wisconsin
2003 - 2006 Member, Faculty Council Nominating Committee, Medical College of Wisconsin
2003 Chairman, Search Committee, Oral Surgery, Medical College of Wisconsin
2004 - 2005 Chairman, Search Committee, Anesthesiology, Medical College of Wisconsin
2005 Member, Search Committee, GCRC Cancer Center Director, Medical College of Wisconsin
2007 - 2008 Member, Search Committee, Chairman of Obstetrics/Gynecology, Medical College of Wisconsin
2011 - 2012 Member, Search Committee, Chairman of Plastic Surgery, Medical College of Wisconsin
2014 - Present Co-chairperson, Human Studies Subcommittee, Medical College of Wisconsin

Hospital
1990 - 1993 Member, Intramural Research Review, Zablocki, VAMC
1991 - 2002 Member, Human Studies Subcommittee, Zablocki, VAMC
1993 - 2002 Member, Research and Development Committee, Zablocki, VAMC
1994 - 1995 Medical Staff Secretary, Executive Committee, John L. Doyne Hospital
1997 - 1999 Member, Clinical Practice Standards Committee, Froedtert Memorial Lutheran Hospital
1998 - 2004 Member, Transfusion Committee, Zablocki, VAMC
1999 Member, Primary Care Task Force, Zablocki, VAMC
1999 Member, Cancer Committee, Zablocki, VAMC, Zablocki, VAMC
1999 Member, Cancer Task Force, Zablocki, VAMC
2002 - Present Member, Tissue Committee, Zablocki, VAMC
2006 - Present Member, Transfusion Committee, Zablocki, VAMC
2013 - Present Member, Ethics Committee, Zablocki, VAMC


MCW TEACHING ACTIVITIES:
Resident and Fellow Education
1990 - 1998 Gastric Duodenal and Pancreatic Surgery
1990 - Present Surgical grand rounds
1992 - Present Medical Physiology
1998 - Present Gastric and Duodenal Surgery
1998 - 2002 Course Director and Development
2001 - Present Inflammatory Bowel Disease Working Group


MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
1994 - 1995 Mark Engelsgjierd, MD, Medical College of Wisconsin

Clinical/Research Fellows
1999 - 2001 Xiauqi Liu, MD, Medical College of Wisconsin
2001 - 2002 Edward Foley, MD, Medical College of Wisconsin
2005 - 2007 Aaron Rogaczewski, MD, Medical College of Wisconsin


EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Clinical/Research Fellows
2005 - 2006 Bruce Brenner, MD, VA Merit Review Entry Program Application


COMMUNITY SERVICE ACTIVITIES:
1993 - 2002 Board of Governors, Mount Mary College, Milwaukee, Wisconsin
1999 - 2002 Chair, Academic and Student Affairs Committee, Mount Mary College, Milwaukee, Wisconsin
2000 - 2002 Chapter Medical Advisory Chair, Wisconsin Chapter Crohn’s and Colitis Foundation of America
2002 Milwaukee Breast and Cervical Cancer Awareness Program, Certificate of Appreciation
2002 Judge, Science Fair, Hayes Bilingual Elementary School, Milwaukee Public Schools, Milwaukee, Wisconsin
2005 Judge, Science Fair, Hayes Bilingual Elementary School, Milwaukee Public Schools, Milwaukee, Wisconsin


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Lyros, O., Rafiee, P., Nie, L., Medda, R., Jovanovic, N., Otterson, M.F., Behmaram, B., Gockel, Ι., Mackinnon, A., Shaker, R., Wnt/β-catenin signaling activation beyond robust nuclear β-catenin accumulation in non-dysplastic Barrett’s esophagus: Regulation via Dickkopf-1, Neoplasia, (submitted, 2015).
2. Rentea, R.M., Lam, V., Biesterveld, B., Fredrich, K.M., Callison, J., Fish, B.L., Baker, J.E., Komorowski, R., Gourlay, D.M., Otterson, M.F., Radiation-Induced Changes in Intestinal and Tissue Nonspecific Alkaline Phosphatase: Implications for Recovery after Radiation Therapy, Radiation Research , (submitted, 2015).
3. Medda, R. Lyros, O., Schmidt, J., Jovanovic, N., Nie, L., Link, B., Otterson, M., Stoner, G., Shaker, R., Raifiee, P., Anti inflammatory and Anti angiogenic Effect of Black Raspberry Extract on Human Esophageal and Intestinal Microvascular Endothelial Cells, Microvascular Research, 2015, Jan;97:167-80, Epub 2014 Oct 28.
4. Nie, L., Medda, R., Lyros, O., Otterson, M.F., Johnson, C.P., Behmram, B., Shaker, R., Rafiee, P., Endothelial-Mesenchymal Transition in Normal Human Esophageal Microvascular Endothelial Cells Co-cultured with Esophageal Adenocarcinoma cells: Role of IL-1β and TGF-β2, American Journal of Physiology- Cell Physiology, 2014 Nov 1;307(9):C859-77, Epub 2014 Aug 27.
5. Durand, M., Phillips, S, Otterson, M., Gutterman, D., The Vascular Renin Angiotensin System Contributes to Endothelial Dysfunction Induced by Transient High Pressure in Human Adipose Microvessels, American Journal of Physiology - Heart and Circulatory Physiology , 2014 Jul 1;307(1):H25-32.
6. Bautista, M.C., Otterson, M.F., Zadvornova, Y., Naik, A.S., Stein, D.J., Venu, N., Perera, L.P., Surgical Outcomes in the Elderly with Inflammatory Bowel Disease are Similar to Those in the Younger Population. Digestive Diseases and Sciences, 2013 Jul 9. [Epub ahead of print] PubMed PMID: 23836319.
7. Titus, R., Kastenmeier, A., Otterson, M.F., Consequences of Gastrointestinal Surgery on Drug Absorption. Nutrition in Clinical Practice, 2013 Jul 8. [Epub ahead of print] PubMed PMID: 23835364.
8. Otterson, M.F., Nie, L., Schmidt, J.L., Link, B.J., Jovanovic, N., Lyros, O., Rafiee, P., EUK-207 Protects Human Intestinal Microvascular Endothelial Cells (HIMEC)against Irradiation –induced Apoptosis through the Bc12 Pathway, Life Sciences , 2012, 91:771-782.
9. Leming, S., Broad, J., Cozens, S.J., Otterson, M., Winchester, W., Lee, K., Dukes, G.E.,Sanger, G.J., GSK962040: a small molecule motilin receptor agonist which increases gastrointestinal motility in conscious dogs, Neurogastroenterology and Motility , 2011, 23:958-964.
10. Williams, J.P., Brown, S.L., Georges, G.E., Hauer-Jensen, M., Hill, R.P., Huser, A.K., Kirsch, D.G., Macvittie, T.J., Mason, K.A., Medhora, M.M., Moulder, J.E., Okunieff, P., Otterson, M.F., Robbins, M.E., Smathers, J.B., McBride, W.H. Animal models for medical countermeasures to radiation exposure. Radiat Res. 2010 Apr;173(4):557-78. PMCID: PMC3021126.
11. Rafiee, P., Binion, D.G., Wellner, M., Nelson, V.M., Floer, M., Manley, S., Otterson, M.F., Modulatory Effect of Curcumin on Survival of Irradiated Human Intestinal Microvascular Endothelial Cells: Role of Akt/mTOR and NFκB, American Journal of Physiology Gastrointestinal and Liver Physiology. 2010, Jun;298(6):G865-77. Epub 2010 Mar 18.
12. Rafiee, P., Stein, D.J., Nelson, V.M., Otterson, M.F., Binion, D.G., Thalidomide Inhibits Inflammatory and Angiogenic Activation of Human Intestinal Microvascular Endothelial Cells (HIMEC), American Journal of Physiology Gastrointestinal and Liver Physiology. 2010 Feb;298(2):G167-76. Epub 2009 Nov 19. PMCID: PMC2822501.
13. Rafiee, P., Binion, D.G., Wellner, M., Nelson, V.M., Floer, M., Manley, S., Otterson, M.F., Effect of radiation on Human Intestinal Microvascular Endothelial Cells (HIMEC): Role of Akt/mTOR and NFB, (submitted, Radiation Research, 2009).
14. Ananthakrishnan, A.N., Issa, M., Barboi, A., Jaradeh, S., Zadvornova, Y., Skaros, S., Johnson, K., Otterson, M.F., Binion, D.G., Impact of Autonomic Dysfunction on Inflammatory Bowel Disease. Journal of Clinical Gastroenterology. 2010 Apr;44(4):272-9.
15. Otterson, M.F., Leming, S.C., Fox, C.J., Moulder, J.E., Propagation of Giant Migrating Contractions Between the Small Intestine, Cecum and Colon during Radiation, Neurogastroenterology and Motility, 2010, Aug;22(8):919-26 . [Epub ahead of print, Jun 7]
16. Gonzaga, J., Ananthakrishnan A.N., Issa, M., Beaulieu, D.B., Zadvornova, Y., Lemke, K., Otterson, M.F., Binion, D.G., Durability of Infliximab in Crohn's Disease - A Single Center Experience, Inflammatory Bowel Disease, 2009 May 21;15(12):1837-1843. [Epub ahead of print]
17. Binion, D.G., Heidemann, J., Li, M.S., Nelson, V.M., Otterson, M.F., Rafiee, P, Vascular Cell Adhesion Molecule-1 (VCAM-1) Expression in Human Intestinal Microvascular Endothelial Cells (HIMEC) is Regulated by PI3K/Akt, MAPK and NF-kappa B: Inhibitory Role of Curcumin, American Journal of Physiology Gastrointestinal and Liver Physiology. 2009 Aug;297(2):G259-68. Epub 2009 Jun 11. PMCID: 2724083
18. Darouiche, R.., Wall, M., Itani, K., Otterson, M.F., Webb, A., Carrick, M., Miller, H., Awad, S., Crosby, C., Mosier, M., AlSharif, A, Berger, D., A Randomized Comparison of Two Antiseptic Preparations for Prevention of Surgical Site Infection, New England Journal of Medicine, 2010, January 7, 362:18-26.
19. Ananthakrishnan A.N., Issa, M., Beaulieu, D.B., Skaros, S., Knox, J.F., Lemke, K., Emmons, J., Lundeen, S.J., Otterson M.F., Binion D.G., History of Medical Hospitalization Predicts Future Need for Colectomy in Patients with Ulcerative Colitis, Inflammatory Bowel Disease, 2009 Feb;15(2):176-81.
20. Beaulieu, D.B., Ananthakrishnan A.N., Issa, M., Rosenbaum, L, Skaros, S., Newcomer, J.R., Kuhlmann, R.S., Otterson, M.F., Emmons, J., Knox, J.F., Binion D.G., Budesonide Induction and Maintenance Therapy for Crohn's Disease during Pregnancy, Inflammatory Bowel Disease, 2009 Jan;15(1):25-8.
21. Davenport, D.L., Henderson, W.G., Hogan, S., Mentzer, R.M., Zwischenberger, J.B., Participants in the Working Conditions of Surgery Residents and Quality of Care Study (Otterson M.F., PI of 1 of 49 centers), Surgery, 144:332-338, 2008.
22. Floer, M., Binion D.G., Nelson, V.M., Wellner, M., Sadeqhi, S., Behmaram, B., Sewell, C., Otterson, M.F., Kurarzik, T., Raifee, P., Role of MutS Homologue 2 (MSH2) in Intestinal Myofibroblast Proliferation During Crohn's Disease Stricture Formation, American Journal of Physiology Gastrointestinal and Liver Physiology, 2008 Sep;295(3):G581-90. Epub 2008 Jul 17. PMCID: 2536780
23. Binion D.G., Otterson M.F., Rafiee, P., Curcumin Inhibits VEGF Mediated Angiogenesis in Human Intestinal Microvascular Endothelial Cells Through COX-2 and MAPK Inhibition, Gut, 2008 Nov;57(11):1509-17. Epub 2008 Jul 2. PMCID: 2582343
24. Ananthakrishnan A.N., Weber, L.R., Knox, J.F., Skaros, S., Emmons, J., Lundeen, S.J., Issa, M., Otterson M.F., Binion D.G., Permanent Work Disability in Crohn's Disease, American Journal of Gastroenterology, 103:154-61, 2008.
25. Ananthakrishnan A.N., Attila T., Otterson M.F., Lipchik R.J., Massey B.T., Komorowski R.A., Binion D.G., Severe pulmonary toxicity after azathioprine/6-mercaptopurine initiation for the treatment of inflammatory bowel disease. Journal of Clinical Gastroenterology, 41:682-8, 2007.
26. Horowitz S., Binion D.G., Nelson V., Kanaa Y., Javadi P., Lazarova Z., Andrekopoulos C., Kalyanaraman B., Otterson M.F., Rafiee P., Increased Arginase Activity and Endothelial Dysfunction In Human Inflammatory Bowel Disease. American Journal of Physiology Gastrointestinal and Liver Physiology, 2007 May;292(5):G1323-36. Epub 2007 Jan 11.
27. Berger, W.L., Kounev, V., Otterson, M.F., Novel Method For Re-Colonoscopy After Percutaneous Cecostomy, Gastrointestinal Endoscopy, 6:1005-6, 2008.
28. Edmiston, C.E., Krepel, C.J., Seabrook, G.R., Towne, J.B., Smith, T.L., Loehrl, T.A., Wackym, P.A., Johnson, C.P., Otterson, M.F., Gajjar, D.A., Krishna, G., Tissue and Fluid Penetration of Garenoxacin in Surgical Patients, Surgical Infections (Larchmt), 8:179-188, 2007.
29. Issa, M., Vijayapal, A., Graham, M.B., Beaulieu, D.B., Otterson, M.F., Lundeen, S.J., Weber, L.R., Komorowski, R.A., Knox, J.F., Emmons, J., Bajaj, J.S., Binion, D.G., Impact of Clostridium difficile on Inflammatory Bowel Disease, Clinical Gastroenterology and Hepatology, 5:345-351, 2007.
30. Hatoum, O.A., Otterson, M.F., Kopelman, D., Miura, H., Sukhotnik, I., Larsen, B.T., Selle, R.M., Moulder, J.E., Gutterman, D.D. Radiation induces endothelial dysfunction in murine intestinal arterioles via enhanced production of reactive oxygen species. Arteriosclerosis Thrombosis and Vascular Biology 2006 Feb;26(2):287-94. Epub 2005 Dec 1.
31. Binion, D.G., Theriot, K. G., Shidham, S., Lundeen, S.J., Hatoum, O.A., Lim, H., J., Otterson, M.F., Clinical Factors contributing to Rapid Re-operation for Crohn's Disease Patients Undergoing Resection and/or Strictureplasty, Journal of Gastrointestinal Surgery, 11:1692-8, 2007.
32. Lundeen, S.J., Otterson, M.F., Binion, D.G., Carman, E.T., Peppard, W.J., Clostridium difficile enteritis: An Early Post-operative Complication in IBD Patients Following Colectomy, Journal of Gastrointestinal Surgery, 11:138-142, 2007.
33. Sudakoff, G.S., Lundeen, S.J., Otterson, M.F., Transrectal and Transvaginal Sonographic Intervention of Infected Pelvic Fluid Collections: A Complete Approach, Ultrasound Quarterly, 21:175-185, 2005.
34. Hatoum, O.A., Spinelli, K.S., Abu-Hajir, M., Attila, T., Franco, J., Otterson, M.F., Telford, G.L., Binion, D.G. Mesenteric Venous Thrombosis in Inflammatory Bowel Disease. Journal Clinical Gastroenterology, 39:27-31, 2005.
35. Ogawa, H., Binion, D.G., Heidemann, J., Theriot, M., Fisher, P.J., Johnson, N.A., Otterson, M.F., Rafiee, P. Mechanisms of MAdCAM-1 Gene Expression in Human Intestinal Microvascular Endothelial Cells. American Journal of Physiology Gastrointestinal and Liver Physiology, 2005 Feb;288(2):C272-81. Epub 2004 Oct 13.
36. Heidemann, J., Ogawa, H., Otterson, M.F., Shidham,V.B., Binion, D.G., Normalization of Plasma D-Dimer Levels Following Successful Treatment of Mesenteric Desmoid Tumour with Interferon alfa-2b and Toremifene, Diseases of the Colon and Rectum, 47(1):118-22, 2004.
37. Woehlck, H., Otterson, M., Yun, H., Connolly, M.D., Eastwood, M.S., Using the Visual Analog Scale:In Reply, Anesthesiology, 100(6):1621-2, 2004.
38. Rafiee, P., Heidemann, J., Ogawa, H., Johnson, N.A., Fisher, P.J., Li, M.S., Otterson, M.F., Johnson, C.P., Binion, D.G., Cyclosporin A Differentially Inhibits Multiple Steps in VEGF Induced Angiogenesis in Human Microvascular Endothelial Cells by Altered Intracellular Signaling, Cell Communications and Signaling 2:3, 2004.
39. Otterson, M.F., Lundeen, S.J., Spinelli, K.S., Sudakoff, G.S., Telford, G.L., Hatoum, O.A., Saeian, K., Yun, H., Binion, D.G., Radiographic Underestimation of Small Bowel Stricturing Crohn's Disease: A Comparison with Surgical Findings, Surgery, 136:854-60, 2004.
40. Hatoum, O.A., Gauthier K.M., Binion, D.G., Miura, H., Telford, G.L. Otterson, M.F., Campbell, W.B., Gutterman, D.D. Novel Mechanism of Vasodilation Inflammatory Bowel Disease, Arterosclerosis Thrombosis and Vascular Biology, 25:2355-61, 2005.
41. Hatoum, O.A., Binion, D.G., Miura, H., Bosnjak, J.J., Otterson, M.F., Telford, G.L., Gutterman, D.D., The Role of Hydrogen Peroxide in Ach-induced Dilation of Human Submucosal Intestinal Microvessels, American Journal of Physiology Heart Circulatory Physiology, 288:H48-54, 2005. Epub 2004 Sep 02.
42. Woehlck, H., Otterson, M., Yun, H., Connolly, M.D., Eastwood, M.S., Colpaert, K., Acetazolamide Reduces Referred Postoperative Pain after Laparoscopic Surgery with Carbon Dioxide Insufflation, Anesthesiology, 99(4):924-8, 2003.
43. Tay, G.S., Binion, D.G., Eastwood, D., Otterson, M.F., Multivariate Analysis Suggests Improved Peri-Operative Outcome in Crohn's Disease Patients Receiving Immunomodulator Therapy Following Segmental Resection and/or Strictureplasty, Surgery, 134:565-573, 2003.
44. Heidemann, J., Spinelli, K. S., Otterson, M.F., Binion, D. G., Case Report: Magnetic Resonance Imaging in the Diagnosis of Epidural Abscess Complicating Perirectal Fistulizing Crohn's Disease. Inflammatory Bowel Disease, 9(2):122-4; 2003.
45. Heidemann, J., Ogawa, H., Dwinell, M. B., Rafiee, P. Maaser, C., Gockel, H.R., Otterson, M.F., Ota, D. M., Lügering, N., Domschke, W., Binion, D.G., Angiogenic Effects of Interleukin 8 (CXCL8) in Human Intestinal Microvascular Endothelial Cells are Mediated by CXCR2. Journal of Biological Chemistry, 7: 278; 8508-15, 2003.
46. Ogawa, H., Rafiee, P., Heidemann, J., Fisher, P.J., Johnson, N.A., Otterson, M.F., Binion, D.G., Mechanisms MAdCAM-1 Gene Expression in Human Intestinal Microvascular Endothelial Cells, American Journal of Physiology Cell Physiol. 288:C272-81, 2005. E-pub 2004, Oct 13.
47. Ogawa, H., Rafiee, P., Fisher, P.J., Johnson, N.A., Otterson, M.F., Binion, D.G., Butyrate Modulates Gene and Protein Expression in Human Intestinal Endothelial Cells, Biochemical and Biophysical Research Communications. 309:512-519, 2003.
48. Heidemann, J., Spinelli, K., Otterson, M.F., Binion, D.G., Case Report: Magnetic Resonance Imaging in the Diagnosis of Epidural Abscess Complicating Perirectal Fistulizing Crohn's Disease, Inflammatory Bowel Disease, 9(2):122-124, 2003.
49. Otterson, M.F., Redlich, P.N., McDonald, A., Thorsen, M.K., Klaas, K.K., Clowry, L.J., Walker, A.P., Sequelae of Cryotherapy in Breast Tissue, Cryobiology, 47:174-178, 2003.
50. Hatoum, O.A., Binion, D.G., Otterson, M.F., Gutterman, D.D. Acquired Microvascular Dysfunction in Inflammatory Bowel Disease: Loss of Nitric Oxide-Mediated Vasodilation. Gastroenterology, 125(1):58-69, 2003.
51. Ogawa, H., Rafiee, P., Heidemann, J., Fisher, P.J., Johnson, N.A., Otterson, M.F., Kalyanaraman, B., Pritchard, K.A. Jr, Binion, D.G. Mechanisms of Endotoxin Tolerance in Human Intestinal Microvascular Endothelial Cells. Journal of Immunology 170(12):5956-64, 2003.
52. Ogawa, H., Rafiee, P., Fisher, P.J., Johnson, N.A., Otterson, M.F., Binion, D.G., Sodium Butyrate Inhibits Angiogenesis of Human Intestinal Microvascular Endothelial Cells through COX-2 Inhibition. FEBS Letters, 554(1-2)88-94, 2003.
53. Heidemann, J., Ogawa, H., Dwinell, M.B., Rafiee, P., Maaser, C., Gockel, H.R., Otterson, M.F., Ota, D.M., Lugering, N., Domscke, W., Binion, D.G., Angiogenic Effects of Interleukin 8 (CXCL8) in Human Intestinal Microvascular Endothelial Cells are Mediated by CXCR2. 278(10):8508-15, 2003. Epub 2002.
54. Ahrendt, G.M., Laud, P., Tjoe, J., Eastwood, D., Walker, A.P., Otterson, M.F., Redlich, P.N., Does Breast Tumor Location Influence Success of Sentinel Lymph Node Biopsy? Journal of the American College of Surgeons, 194:278-84, 2002.
55. Rafiee, P., Johnson, C.P., Li, M.S., Ogawa, H., Heidemann, J., Fisher, P.J., Lamirand, T.H., Otterson, M.F., Wilson, K.T., Binion, D.G., Cyclosporine A Enhances Leukocyte Binding by Human Intestinal Microvascular Endothelial Cells through Inhibition of p38 MAPK and iNOS: Paradoxical Pro-inflammatory Effect on the Microvascular Endothelium, Journal of Biological Chemistry, 277:35605-35615, 2002.
56. Sato, A., Miura, H., Liu, Y., Somberg, L.B., Otterson, M.F., Demeure, M.J., Schulte, W.J., Eberhardt, L.M., Loberiza, F.R., Sakuma, I., Gutterman, D.D., Effect of Gender and Climateric Status on Bradykinin - Induced Endothelial Dilation in Human Microvessels, American Journal of Physiology, 283(3):H845-52, 2002.
57. Koch, T.R., Otterson, M.F., Telford, G.L., Nitric Oxide Production is Diminished in Colonic Circular Muscle from Acquired Megacolon, Diseases of the Colon and Rectum, 43:821-828, 2000.
58. Binion, D., Rafiee, P., Ramanujam, K.S., Fu, S., Fisher, P.J., Rivera, M.T., Johnson, C.P., Otterson, M.F., Telford, G.L., Wilson, K.T., Deficient iNOS in Inflammatory Bowel Disease Intestinal Microvascular Endothelial Cells Results in Increased Leukocyte Adhesion, Free Radical Biology Medicine, 29:881-8, 2000.
59. Ruan, E.A., Simbasiva, R., Burdick, J.S., Stryker, S.J., Telford, G.L., Otterson, M.F., Opara, E.C., Koch, T.R., Glutathione Levels in Chronic Inflammatory Disorders of the Human Colon, Nutrition Research, 17:463-473,1997.
60. Koch, T.R., Schulte-Bockholt, A., Otterson, M.F., Telford, G.L., Stryker, S.J., Ballard, T., Opara, E.C., Decreased Vasoactive Intestinal Peptide and Glutathione Depletion in Acquired Megacolon, Digestive Diseases and Sciences, 41:1409-1416, 1996.
61. Otterson, M.F., Koch, T.R., Zhang, Z., Leming, S.C., Moulder, J.E., Fractionated Irradiation alters Enteric Neuroendocrine Products, Digestive Diseases and Sciences, 40:1691-1702, 1995.
62. Schulte-Bockholt, A., Fink, J.G., Meier, D.A., Otterson, M.F., Telford, G.L., Hopp, K., Koch, T.R., Expression of mRNA for Vasoactive Intestinal Peptide in Normal Human Colon and During Inflammation, Molecular and Cellular Biochemistry, 142:1-7, 1995.
63. Walsh, B.A., Grunert, B.K, Telford, G.L., Otterson, M.F., Multidisciplinary Management of Altered Body Image in the Ostomy Patient, Journal of Wound Ostomy Continence Nursing, 22:227-236, 1995.
64. Schulte-Bockholt, A., Meier, D.A., Hopp, K., Stadelmann, A., Otterson, M.F., Telford, G.L., Koch, T.R., Gene Expression and Transcript Size of the Prepro-peptde VIP/PHM-27 in Normal Human Tissue, Neuroscience Letters, 164:101-104, 1993.
65. Erickson, B., Otterson, M.F., Sarna, S.K., Moulder, J.E., Altered Motility Causes the Early Gastrointestinal Toxicity of Irradiation, International Journal of Radiation Oncology / Biology / Physics, 28:905-912, 1994.
66. Otterson, M.F., Sarna, S.K., Neural Control of Small Intestinal Giant Migrating Contractions, American Journal of Physiology 266, (Gastrointest. Liver Physiol. 29): G576-G584, 1994.
67. Koch, T.R., Otterson, M.F., Roddy, D.R., Go,V.L.W., Characterization of Neuropeptides Extracted from Canine Intestine, Neuropeptides, 24: 359-365, 1993.
68. Koch, T.R., Schulte-Bockholt, A., Telford, G.L., Otterson, M.F., Murad, T.M., Stryker, S.J., Acquired Megacolon is Associated with Alteration of Vasoactive Intestinal Peptide Levels and Acetylcholinesterase Activity, Regulatory Peptides, 48:309-319, 1993.
69. Sarna, S.K., Otterson, M.F., Ryan, R.P., Cowles,V.E., Nitric Oxide Regulates Migrating Motor Complex Cycling and its Postprandial Disruption, American Journal of Physiology 265 (Gastrointest. Liver Physiol. 28): G759-G766, 1993.
70. Telford, G.L., Varner, D.E., McManus, L.L., Walgenbach-Telford, S., Otterson, M.F., Condon, R.E., Sarna, S.K., Effect of Daily Loperamide Administration on Gastrointestinal Myoelectric Activity, Journal of Gastrointestinal Motility, 4:25-31, 1992.
71. Otterson, M.F., Sarna, S.K., Lee, M.B., Fractionated Doses of Ionizing Radiation Alter Postprandial Small Intestinal Motor Activity, Digestive Diseases and Sciences, 37: 709-715, 1992.
72. Otterson, M.F., Sarna, S.K., Leming, S.C., Moulder, J.E., Fink, J., Effects of Fractionated Doses of Ionizing Radiation on Colonic Motor Activity, American Journal of Physiology, 263 (Gastrointest. Liver Physiol. 26):G518-G526, 1992.
73. Sarna, S.K., Otterson, M.F., Small Intestinal Amyogenesia and Dysmyogenesia Induced by Morphine and Loperamide, American Journal of Physiology, 258 (Gastrointest. Liver Physiol. 21): G282-G289, 1990.
74. Otterson, M.F., Sarna, S.K., Gastrointestinal Motor Effects of Erythromycin, American Journal of Physiology, 259 (Gastrointest. Liver Physiol. 22): G355-G363, 1990.
75. Hou, J., Otterson, M.F., Sarna, S.K., Local Effects of Substance P on Colonic Motor Activity in Different Experimental States, American Journal of Physiology, 256 (Gastrointest. Liver Physiol. 19): G997-G1004, 1989.
76. Carter, D., Choi, H., Telford, G., Otterson, M., Chitapalli, K., Pintar, K., Lymphadenopathy and Entero-vesical Fistula in Fabry's Disease, American Journal of Clinical Pathology, 90:726-731, 1988.
77. Otterson, M.F., Sarna, S.K., Moulder, J.E., Effects of Fractionated Doses of Ionizing Radiation on Small Intestinal Motor Activity, Gastroenterology, 95:1249-1257, 1988.
78. Carter, D., Choi, H., Otterson, M., Telford, G.L., Primary Adenocarcinoma of an Ileostomy after Colectomy for Ulcerative Colitis, Digestive Diseases and Sciences, 33:509-512, 1988.

Books, Chapters, and Reviews
1. Williams, J.P., Brown, S.L., Georges, G., Huser, A.K., Hill, R.P., Hauer-Jensen, M., Kirsch, D.G., Mason, K.A., MacVittie, T.J., Medhora, M.M., Moulder, J.E., Okunieff, P., Otterson, M.F., Robbins, M.E., Smathers, J.B., McBride, W.H., Animal Models for Medical Countermeasures: a CMCR Workshop Report, Radiation Research, 173, 2010, E-pub ahead of print, January 28, 2010.
2. Otterson, M.F., Invited reviewer for Evidence Based Reviews in Surgery, a joint program of Canadian Association of General Surgeons L'Association Canadienne des Chirurgiens Généraux & the American College of Surgeons, The recurrence of Crohn's disease after ileocolic resection is not affected by anastomotic type: results of a multicenter, randomized, controlled trial, 2009.
3. Kosinski, L., Ludwig, K, Otterson, M.F., Diverticular Disease, In: Fifth Edition of the Textbook Surgery: Scientific Principles and Practice, Greenfield, L.J., Mulholland, M.W., Oldham, K.T., Zelenock, G.B., Lillemoe, K.D., eds, Lippincott-Raven. 2009, (submitted)
4. Otterson, M.F., Effects of Radiation upon Gastrointestinal Motility, World Journal of Gastroenterology, 13:2684-92, 2007.
5. Otterson, M.F., Christians, K., Radiation and Surgery, General Surgery: Principles and International Practice, K.I. Bland, M.W. Büchler, A. Csendes, O.J. Garden, M.G. Sarr, and J. Wong, Springer, 2009, pp631-638.
6. Otterson, M. F., Binion, D.G., Karp, S.J., Soybel, D.J., Mun, E.C., Matthews, J.B., Small Intestine, Shackelford's Surgery of Alimentary Tract , Yeo, C.J., Dempsey, D.T., Klein, A.S., Pemberton, J.H., Peters, J.H., ed., Saunders Elsevier, 2007, pp. 988-1024.
7. Otterson, M.F., How to Protect Your Research Time, American College of Surgeons, Meeting publication, 2003.
8. Otterson, M.F., Korus, G., Diverticular Disease, In: Fourth Edition of the Textbook Surgery: Scientific Principles and Practice, Greenfield, L.J., Mulholland, M.W., Oldham, K.T., Zelenock, G.B., Lillemoe, K.D., eds, Lippincott-Raven. 2006, 1130-1137.
9. Otterson, M.F., Normal Motility and Smooth Muscle Function, In: Colonic Diseases, Koch, T.R., ed. Humana Press, Inc, 2003, pp 25-34.
10. Telford, G.L., Otterson, M.F., Telford, S., Diverticular Disease, In: Colonic Diseases, Koch, T.R., ed. Humana Press, Inc, 2003, pp 409-422.
11. Otterson, M.F., Radiation Enteropathy, In: Second Edition of The Practice of General Surgery, Cioffi, W.G., Clark, O.H., Gamelli, .R.L, Partridge, E.E., Sarr, M.G., Seeger, J.M., Shah, J.P., Simms, H.H., Tracy, T.F., eds, W.B. Saunders, 2002, pp 442-446.
12. Otterson, M.F., Binion, D.G., Crohn's Disease Surgery 2002: Concomitant Medical Therapy Improves Surgical Outcome, In: Gastrointestinal Disease Course Book, 88th Annual Clinical Congress of the American College of Surgeons pp 26-28.
13. Otterson, M.F., Telford, G.L., Diverticular Disease, In: Third Edition of the Textbook Surgery: Scientific Principles and Practice, Greenfield, L.J., Mulholland, M.W., Oldham, K.T., Zelenock, G.B., Lillemoe, K.D., eds, Lippincott-Raven. 2001, pp 137-1143.
14. Sarr, M., Collen, J., Otterson, M.F., Gastrointestinal Motility, In: Surgical Research, Souba, W., Wilmore, D., eds, Academic Press, 2001, pp 507-532.
15. Koch, T.R., Schulte-Bockholt, A., Telford, G.L., Otterson, M.F., Stryker, S.J., Opara, E.C., Neuroendocrine pathologies in IBD: Epiphenomenon or Pathophysiological Key? In Falk Symposium No. 98, Systemic Manifestations of IBD: The pending challenge for subtle diagnosis and treatments, Lembecke, B., Kruis, W., Sartor, R.B. (Eds)., Kluwer Academic Publishers, Dordrecht, 1998, pp 41-54.
16. Telford, G.L., Otterson, M.F., Diverticular Disease, In: Second Edition of the Textbook Surgery: Scientific Principles and Practice, Greenfield, L.J., Mulholland, M.W., Oldham, K.T., Zelenock, G.B., Lillemoe, K.D., eds, Lippincott-Raven, 1997, pp 1151-1157.
17. Sarna, S.K., Otterson, M.F., Cowles, V.E., Telford, G.L., Investigations of Myogenic, Neural and Chemical Control of Small Intestinal Motor Activity, In: Essentials of Experimental Surgery, Jensen, S., Gregerson, H., Moody, F., Shokoush-Amiri, M., eds, Harwood Academic, Amsterdam, 1996, pp 39/1-21.
18. Otterson, M.F., Sarna, S.K., Moulder, J.E., Radiation Effects on Gastrointestinal Motility and Potential Therapies, Proceedings of the Second Consensus Development Conference on the Treatment of Radiation Injuries, Pergamon Press, Bethesda, Maryland, 1996, pp 207-216.
19. Otterson, M.F., Intestinal Obstruction, In: Manual of Surgical Therapeutics, 9th ed., Condon, R.E., Nyhus, LM, eds., Little, Brown and Co., 1995, pp 279-285.
20. Engelsgjerd, M., Otterson, M.F., Condon, R.E., Chronic Intestinal Pseudo-Obstruction, Advances in Surgery, Cameron, J.L. et al, eds., Mosby - Yearbook, Inc., 28:397-405, 1995.
21. Otterson, M.F., Condon, R.E., Disorders of the Stomach and Duodenum, In: Surgery of the Esophagus, Stomach and Small Intestine, 5th ed., Nyhus, L.M., Wastell, C., Donahue, P.E., eds., Little, Brown and Co., 1995, pp 691-729.
22. Otterson, M.F., Summers, R.W., Postirradiation Alterations in Small and Large Bowel Motility, In: Radiation and the Gastrointestinal Tract, Dubois, A., King, G.L., Livengood, D.R., eds., CRC Press, 1994, pp 77-88.
23. Otterson, M.F., Krzywda, E., Andris, D., Hickman Catheter-Related Infections, Surgical Infections: Index and Reviews, 2:8-9, 1994.
24. Mason, G.R., Kahrilas, P.J., Otterson, M.F., Lang, I.M., Telford, G.L., Telford, S.W., Sarna, S.K., Cowles, V.E., Koch, T.R., Debas, H.T., Gittes, G., Jaffe, B.M., Dudrick, S.J., Latifi, R., Castro, G.A., The Digestive System, In: The Physiologic Basis of Surgery, O'Leary, J.P., ed., Williams and Wilkins, 1993, pp 340-375.
25. Sarna, S.K., Otterson, M.F., Myoelectric and Contractile Activities, In: Atlas of Gastrointestinal Motility in Health and Disease, Schuster, M.M., ed., Williams and Wilkins, 1993, pp 3-42.
26. Otterson, M.F., Gleysteen, J.J., Intestinal Obstruction, In: Manual of Surgical Therapeutics, 8th ed., Condon, R.E., Nyhus, L.M., eds., Little, Brown and Co., 1992, pp 254-260.
27. Sarna, S.K., Otterson, M.F., Cowles, V.E., Sethi, A.K., Telford, G.L., In vivo Motor Response to Gut Inflammation, In: The Effects of Immune Cells and Inflammation on Smooth Muscle and Enteric Nerves, Snape, W.J., Jr., Collins, S., eds., CRC Press, Inc., 1990, pp 83-94.
28. Sarna, S.K., Lang, I.M., Gleysteen, J.J., Otterson, M.F., Central vs. Enteric Neural Control of Small Intestinal Migrating Motor Complexes, In: Nerves and the Gastrointestinal Tract, Singer, M.V., Goebel, H., eds., Lancaster: MTP Press, 1989, pp 746-752.
29. Otterson, M.F., Surgical Approach to Radiation Enteritis, In:UpToDate, Soybel, D.I., Editor in Chief, General Surgery, in press, 2015.
30. Otterson, M.F., Why Do I Need to Have Surgery for My Crohn’s Disease?: Surgical Management of Crohn’s Disease, In: Inflammatory Bowel Disease: A Patient Centered, Point-of-Care Reference Guide for Busy Gastroenterology Providers, Stein, D.J. and Shaker, R. eds, Springer, 2015, pp 201-206.
31. Ridolfi, T., Otterson, M.F., My Fistulas are Just not Healing. What are You Going to do About it? Surgical Management of Perianal Crohn’s Disease, In: Inflammatory Bowel Disease: A Patient Centered, Point-of-Care Reference Guide for Busy Gastroenterology Providers, Stein, D.J. and Shaker, R. eds, Springer, 2015, pp 195-200.
32. Kosinski, L., Ludwig, K, Otterson, M.F., Diverticular Disease, In: Sixth Edition of the Textbook Surgery: Scientific Principles and Practice, Greenfield, L.J., Mulholland, M.W., Oldham, K.T., Zelenock, G.B., Lillemoe, K.D., eds, Lippincott-Raven. 2015, (submitted)
33. Klinger, D., Sudakoff, G, Otterson, M. F., Small Bowel Obstruction, Shackelford's Surgery of Alimentary Tract , Yeo, C.J., Dempsey, D.T., Klein, A.S., Pemberton, J.H., Peters, J.H., ed., Saunders Elsevier, 2011, (in press).

Non-Refereed Journal Publications/Original Papers
1. Otterson, M.F., Lundeen, S. J., Binion, D.G., C. difficile and Inflammatory Bowel Disease, a letter to the editor, American Journal of Surgery, (accepted, 2009).
2. Skaros, S., Lundeen, S., Mathison, C., Otterson, M.F., Stomas, Ostomies and Appliances: Implications for Aquatic Therapy, Aquatic Therapy Journal, 9:3-7, 2006
3. Otterson, M.F., Redlich, P.N., Gastroesophageal Reflux Disease (GERD), Digestive Health Matters, Newsletter of the International Foundation for Functional Gastrointestinal Disorders, 2:1-3, 2000.
4. Otterson, M.F., Sarr, M., Normal Physiology of Small Intestinal Motility, Surgical Clinics of North America, 3:1173-1199, 1993.
5. Sarna, S.K., Otterson, M.F., Gastroduodenal Motility, Current Opinion in Gastroenterology, 9:922-929,1993.
6. Sarna, S.K., Otterson, M.F., Small Intestinal Physiology and Pathophysiology, Gastroenterology Clinics of North America, 18:375-404, 1989.
7. Otterson, M. F., Sarna, S.K., Gastrointestinal Motility: Some Basic Concepts, European Journal of Pharmacology, 36 Suppl. 1:7-14, 1988.

Abstracts
1. Ho, K.C., Garancis, J.C., Yeung, J., Otterson, M.F., The Morphological Changes in Myelinated Peripheral Nerve Fibers Exposed to Low Sodium and High Potassium Concentrations, Journal of Neuropathology and Experimental Neurology, 43:345, 1984.
2. Otterson, M.F., Sarna, S.K., Therapeutic Doses of Ionizing Radiation Induce Giant Migrating Contractions in the Small Intestine, Proceedings of the XI International Symposium on Gastrointestinal Motility, Oxford, England, 106, 1987.
3. Otterson, M.F., Sarna, S.K., Effects of Therapeutic Doses of Ionizing Radiation on Small Intestinal Motor Activity, Gastroenterology, 94:621, 1988.
4. Hou, J., Otterson, M.F., Sarna, S.K., ENS Effects of Substance P on Colonic Motor Activity in the Conscious and Anesthetized States and During Laparotomy, Gastroenterology, 95:871, 1988.
5. Otterson, M.F., Sarna, S.K., Motor Patterns Associated with the Gastrointestinal Side Effects of Erythromycin, Gastroenterology, 95:883, 1988.
6. Otterson, M.F., Sarna, S.K., Nelans, N.H., Comparison of Gastrointestinal Side Effects of Erythromycin, Roxithromycin and Clarithromycin, FASEB Journal, 3:A850, 1989.
7. Otterson, M.F., Sarna, S.K., Therapeutic Doses of Ionizing Radiation Alter Postprandial Small Intestinal Motor Activity, Gastroenterology, 95:A690, 1989.
8. Varner, D.E., Telford, G.L., Condon, R.E., Otterson, M.F., Sarna, S.K., Chronic Oral Administration of the Opioid Agonist Loperamide alters Small Intestinal Myoelectric Activity, Gastroenterology, 95:A526, 1989.
9. Sarna, S.K., Ryan, R.P., Otterson, M.F., Lang, I.M., Giant Migrating Contractions in the Cat Small Intestine, Gastroenterology, 96:A440, 1989.
10. Otterson, M.F., Sarna, S.K., Enteric Neural Control of Giant Migrating Contractions, Journal of Gastrointestinal Motility, 1:50, 1989.
11. Varner, D.E., Telford, G.L., Condon, R.E., Otterson, M.F., Sarna, S.K., Chronic Administration of the Opioid Agonist Loperamide Alters Small Intestinal Myoelectric Activity, Journal of Gastrointestinal Motility, 1:70, 1989.
12. Otterson, M.F., Sarna, S.K., Control of Smooth Muscle Contractions During Obliteration of Electrical Control Activity, The Physiologist, 32:175, 1989.
13. Otterson, M.F., Sarna, S.K., Effects of Fractionated Doses of Radiation on Colonic Motor Activity, Gastroenterology, 100:478, 1991.
14. Sarna, S.K., Otterson, M.F., Kindt, M.V., Motility Basis of Intussusception, Gastroenterology, 100:A490, May 1991.
15. Otterson, M.F., Sarna, S.K., Small Intestinal Contractions Associated with Vomiting Following Transection of the Gut, FASEB Journal, 6:3345, 1992.
16. Otterson, M.F., Koch, T.R., Zheng, Z., Sarna, S.K., Radiation Alters Enteric Neuroregulatory Peptides, Gastroenterology, 102:A497, 1992.
17. Koch, T., Schulte-Bockholt, A., Telford, G., Otterson, M.F., Murad, T.M., Stryker, S.J., Idiopathic Acquired Megacolon is Associated with Alteration of Enteric Nervous System Products, Gastroenterology, 102:A469, 1992.
18. Sarna, S.K., Otterson, M.F., The Prokinetic Effects of Cisapride on the Colon and the Small Intestine, Gastroenterology, 102:A508, 1992.
19. Sarna, S.K., Hou, J., Lang, I.M., Ryan, R.P., Otterson, M.F., Brandon, A., CNS Stimulation of Colonic Motor Activity by TRH, Gastroenterology, 102:A508, 1992.
20. Otterson, M.F., Sarna, S.K., Leming, S.C., Ginocchio, T.E., Contractile Coordination between the Canine Small Bowel, Cecum and Colon with Irradiation, Gastroenterology, 103:1385, 1992.
21. Sarna, S.K., Otterson, M.F., Ryan, R.P., Cowles, V.E., NO NANC Nerves Modulate Migrating Motor Complexes (MMCs) and Postprandial State, Gastroenterology, 103:1375, 1992.
22. Schulte-Bockholt, A., Mustin, E., Telford, G., Otterson, M.F., Sarr, M.G., Koch, T.R., Distribution of Intrinsic Neuropeptides and Cholinergic Nerve-specific Enzymes in the Human Intestinal Tract, Regulatory Peptides, 40:247, 1992.
23. Koch, T.R., Schulte-Bockholt, A., Mustin, E., Otterson, M.F., Telford, G., Stryker, S.J., Murad, T.M., Abnormalities of Intrinsic Neuropeptides in Idiopathic Megacolon, Regulatory Peptides, 40:184, 1992.
24. Sarna, S.K., Karaus, M., Hogan, W.J., Soergel, K.H., Otterson, M.F., Arndorfer, R., Motor Correlates of Idiopathic Abdominal Pain, Gastroenterology, 104:A576, 1993.
25. Otterson, M.F., Koch, T.R., Zhang, Z., Leming, S.C., Sarna, S.K., Enteric Cholinergic Enzyme Activity is Altered by Irradiation, Gastroenterology, 104:A562, 1993.
26. Schulte-Bockholt, A., Fink, J.G., Otterson, M.F., Telford, G.L., Hopp, K., Meier, D.A., Koch, T.R., Gene Expression of VIP in Sigmoid Colon from Chronic Ulcerative Colitis (CUC), Gastroenterology, 104:A578, 1993.
27. Schulte-Bockholt, A., Meier, D.A., Otterson, M.F., Telford, G.L., Koch, T.R., A Potential Molecular Mechanism of Aging: VIP mRNA Transcript size in Human Sigmoid Colon, Gastroenterology, 104:A646, 1993.
28. Schulte-Bockholt, A., Fink, J.G., Otterson, M.F., Telford, G.L., Hopp, K., Koch, T.R., VIP-Gen-Expression in Sigma bei Colitis ulcerosa, Zeitschrift f. Gasdtroenterologie, 31(9):507, 1993.
29. Fink, J.G., Schulte-Bockholt, A., Moulder, J.E., Koch, T.R., Otterson, M.F., Effect of Fractionated External Beam Radiation on Neuronal Cell Products in Rat Ileum and Colon, Gastroenterology, 104:A507, 1993.
30. Helm, J.F., Sarna, S.K., Otterson, M.F., Ryan, R.P., Paradoxical Inhibition of Motor Activity in the Human Cecum and Appendix after a Meal is Mediated by Cholinergic Nerves, Gastroenterology, 104:A520, 1993.
31. Otterson ,M.F., Fox, C., Leming, S.C., Sarna, S.K., Moulder, J.E., Interruption of Ileal Myenteric Plexus Alters the Colonic Motor Response to Irradiation, Journal of Gastrointestinal Motility, 5:209, 1993.
32. Otterson, M.F., Leming, S.C., Sarna, S.K., Contractile Mechanisms of GI Morbidity with Cisplatinum, Gastroenterology, 106:A553, 1994.
33. Koch, T.R., Otterson, M.F., Telford, G.L., Enhancement of Muscarinic, Cholinergic Nerve-Mediated Contractions of Human Colonic Circular Muscle Following Blockade of NO Synthesis, Gastroenterology, 106:A525, 1994.
34. Fink, J.G., Mustin, E., Otterson, M.F., Telford, G.L., Schulte-Bockholt, A., Koch, T.R., In Situ Hybridization Reveals Nonspecific Mucosal Signal in Human Colon Using cDNA to Choline Acetyltransferase (ChAT), Gastroenterology, 106:A553, 1994.
35. Koch, T.R., Meier, D.A., Mustin, E., Otterson, M.F., Telford, G.L., Ballard, T., Opara, E.C., Mechanisms of Altered Expression of VIP in Adult Acquired Megacolon, Digestive Diseases and Sciences, 39:1740, 1994.
36. Koch, T.R., Otterson, M.F., Telford, G.L., In Vitro Quantitation of an Inhibitory Response Evoked in human Colonic Circular Muscle, Digestive Diseases and Sciences, 39:1739, 1994.
37. Otterson, M.F., Leming, S.C., Sarna, S.K., Contractile Mechanisms of Gastrointestinal Morbidity with Cisplatinum, World Journal of Surgery (Supplement) S20, 1994.
38. Koch, T.R., Schulte-Bockholt, A., Otterson, M.F., Telford, G.L., Stryker, S.J., Ballard, T., Opara, E.C., Decreased Expression of VIP in Adult Acquired Megacolon is Associated with Depletion of Colonic Glutathione, Gastroenterology, 108:A630, 1995.
39. Otterson, M.F., Leming, S.C., Moulder, J., Engelsgjerd, M., 5HT3 Antagonist Blocks Contractions Associated With Abdominal Cramping, Gastroenterology, 108:A662, 1995.
40. Ruan E., Otterson, M.F., Telford, G.L., Stryker, S.J., Alexander, C., Rao, S., Koch, T.R., Increased Neuronal Nitric Oxide Synthase Activity in IBD Appears to be Related to Inflammation, Gastroenterology, 108:A1002, 1995.
41. Ruan, E., Otterson, M.F., Telford, G.L., Stryker, S.J., Rao, S., Farag, A., Opara, E.C., Koch, T.R., Glutathione Deficiency in IBD is Related to Colonic Inflammation, Gastroenterology, 108:A906, 1995.
42. Ruan, E., Koch, T.R., Otterson, M.F., Telford, G.L., Stryker, S.J., Rao, S., Farag, A., Opara, E.C., Increased Neuronal No Synthase in IBD is Associated with Glutathione Deficiency, American Journal of Physiology, 90:1649, 1995.
43. Otterson, M.F., Leming, S., Moulder, J., Dawes, L., Intraluminal Bile Enhances Radiation Induced Giant Contractions, Gastroenterology, 110:A728, 1996.
44. Otterson, M.F., Leming, S., Moulder, J., Dawes, L., Intraluminal Bile Amplifies Radiation Induced Colonic Giant Contractions, Digestive Diseases and Sciences, 41:1904, 1996.
45. Koch, T.R., Otterson, M.F., Telford, G.L., Cholinergic Nerve-Mediated Contraction of Human Colonic Circular Smooth Muscle from Acquired Megacolon are not Enhanced by Blockade of NO Synthase, Gastroenterology, 112:A763, 1997.
46. Otterson, M.F., Leming, S.C., Moulder, J.E., Central NK1 Receptors Mediate Radiation Induced Emesis, Gastroenterology, 112:A801, 1997.
47. Schmidt, M.S., Gardner, P.M., Redlich, P.N., Pinnell, S., Walker, A.P., Otterson, M.F., Ozker, K., Collier, B.D., Breast Lymphoscintigraphy: High-Volume Injection Technique Improves Sentinel Lymph Node Visualization, Journal of Nuclear Medicine, 39:25P, 1998.
48. Otterson, M.F., Leming, S., Liu, X., Moulder, J., Radiation Induced Changes in Small Intestinal Motility: A Role for the NMDA Receptor, Gastroenterology, 114:A816, 1998.
49. Otterson, M.F., Leming, S., Liu, X., Moulder, J., The Role of the NMDA Receptor in Radiation Induced Colonic Motility, Digestive Disease and Sciences, 43:1590, 1998.
50. Otterson, M.F., Leming, S., Liu, X., Moulder, J., The NK1 Receptor Modifies the Colonic Contractile Response to Radiation, Gastroenterology, 116:A1055, 1999.
51. Otterson, M.F., Leming, S., Liu, X., Moulder, J., NOS Inhibition Reduces the Contractile Response to Irradiation, Gastroenterology, 118:A2134, 2000.
52. Otterson, M.F., Leming, S., Liu, X., Moulder, J., Ho, W., Sharkey, K., Enteric Neural Plasticity and Disordered Motility Following Irradiation, Gastroenterology, 118:A2110, 2000.
53. Ahrendt, G., Laud, P., Tjoe, J. Eastwood, D., Walker, A.P., Otterson, M.F., Redlich, P.N., Does Breast Tumor Location Influence Success of Sentinel Lymph Node Mapping? Journal of American College of Surgeons, 194:278-84, 2002.
54. Otterson, M.F., Leming, S., Liu, X., Moulder, J., Ho, W., Sharkey, K., Long-term Neurochemical and Motility Adaptations Associated with Irradiation, Gastroenterology, 120:A109, 2001).
55. Stein, D.J., Raifiee, P., Taras, A., Lamirand, T.H., Fisher, P.J., Hitoshi, O., Telford, G.L., Otterson, M.F., Johnson, C.J., Binion, D.G., Thalidomide Inhibits Inflammatory and Angiogenic Activation of Human Intestinal Microvascular Endothelial Cells (HIMEC), Gastroenterology, 120:A278, 2001.
56. Prajappati, D.N., Otterson, M.F., Kim, J.P., Emmons, J., Binion, D.G., Post-Operative use of Infliximab in High-Risk Crohn's Disease (CD) Patients Following Multiple Stricturoplasties, American Journal of Gastroenterology, 96:S304-305, 2001.
57. Foley, E., Callison, J., Leming ,.S, Moulder, J., Otterson, M.F., Genetic Influences on Colonic Motility Changes Induced by Ionizing Radiation, Gastroenterology, 122:A-411, 2002.
58. Raifiee, P., Ogawa, H., Fisher, P.J., Taras, A., Otterson, M.F., Binion, D.G., Antiangiogenic Effect of Radaition on Human Intestinal Microvascular endothelial cells (HIMEC) Involves Inhibition of VEGF Induced Signal Transduction, Gastroenterology, 122:A-438, 2002.
59. Raifiee, P., Ogawa, H., Lamirand, T.H., Fisher, P.J., Otterson, M.F., Telford, G.L., Binion, D.G., Heat Shock Modulates Inflamatory Activation of Human Intestinal Microvascular Endothelial Cells (HIMEC), Gastroenterology, 122:A-436, 2002.
60. Ogawa, H., Raifiee, P., Lamirand, T.H., Fisher, P.J., Heiderman, J., Otterson, M.F., Telford, G.L., Fukushima, K., Binion, D.G., Expression of Mucosal Adressin (MadCAM 1) and Peripheral Node Addressin (CD34) in Human Gastrointestinal Microvascular Endothelial Cells, Gastroenterology, 122:A-436, 2002.
61. Heiderman, J., Dwinell, M.B., Raifiee, P., Ogawa, H., Lamirand, T.H., Fisher, P.J., Otterson, M.F., Lugering, N., Domscheke, W., Binion, D.G., Mechanisms of Interleukin 8 (IL8) Induced Angiogenesis in Human Intestinal Microvascular Endothelial Cells (HIMEC), Gastroenterology, 122:A-437, 2002.
62. Ogawa, H., Heiderman, J., Raifiee, P., Lamirand, T.H., Fisher, P.J., Otterson, M.F., Telford, G.L., Fukushima, K., Domscheke, W., Binion, D.G., Endotoxin Tolerance and Toll Like Receptor (TLR) Expression in Human Intestinal Microvascular Endothelial Cells (HIMEC), Gastroenterology, 122:A-435, 2002.
63. Ogawa, H., Rafiee, P., Fisher, P., Johnson, N., Heidemann, J., Otterson, M., Binion, D.G., MAdCAM-1 Expression in Human Intestinal Microvascular Endothelial Cells (HIMEC) is Regulated by the P13K/Akt and NFkB Pathways, Gastroenterology, 124:A-148, 2003.
64. Rafiee, P., Hatoum, O.A., Wilson, K.T., Otterson, M., Gutterman, D.D., Binion, D.G., Physiologic Expression of Cox2 and PGE2 in Human Intestinal Microvessels and Isolated Endothelial Cells (HIMEC), Gastroenterology, 124:A-148, 2003.
65. Otterson, M.F., Leming, S., Gunnet, J., Hageman, W., The effect of RWJ 68023, a novel motilin antagonist, on rabbit small intestinal motility, Gastroenterology, 124:A-163, 2003.
66. Hatoum, O.A., Binion, D.G., Otterson, M.F., Gutterman, D.D., Acquired microvascular dysfunction in inflammatory bowel disease (IBD): Loss of nitric oxide mediated vasodilation, Gastroenterology, 124:A-329, 2003.
67. Ogawa, H., Heidemann, J., Rafiee, P., Fisher, P., Johnson, N., Otterson, M., Binion, D.G., Endotoxin tolerance in human intestinal microvascular endothelial cells (HIMEC) involves selective modulation of gene expression and altered MAPK signaling, Gastroenterology, 124:A-338, 2003.
68. Koch, T.R., Otterson, M.F., Telford, G.L., Quantitation of an Inhibitory Response Induced in Human Colonic Circular Muscle by the Release of Inhibitory Neurotransmitters, (accepted, International Gut Hormones).
69. Hatoum, O.A., Binion, D.G., Otterson, M.F., Telford, G.L., Gutterman, D.D., Vascular Dysfunction in Inflammatory Bowel Disease, American Heart Association Meeting, (accepted, 2002).
70. Attila, T., Prajapati, D.N., Otterson, M.F., Binion, D.G., Azathioprine Associated Pulmonary Nodules in a Patient with Crohn's Disease, American College of Gastroenterology Meeting, (accepted, 2002).
71. Tay, G.S., Otterson, M.F., Binion, D.G., Improved peri-operative surgical outcome in Crohn's disease patients receiving concomitant immunomodulator therapy, American College of Gastroenterology Meeting, (accepted, 2002).
72. Tan, A., Saeian, K., Knox, J., Emmons, J., Calabrese, L., Darius, R., Devang, P., Kugathasan, S., Otterson, M.F., Binion, D.G., Correlation of short inflammatory bowel disease questionnaire (SIBDQ) with clinical status in routine management of Crohn's disease (CD) patients including ostomates, American Gastroenterological Association (submitted, 2002).
73. Otterson, M.F., Lundeen, S., Binion, D.G., Spinelli, K., Telford, G., Sudakoff, G., Saeian, K., Radiographic Underestimation of Small Bowel Stricturing Crohn's Disease: A Comparison with Surgical Findings, Central Surgical Association, (accepted, 2004).
74. Hatoum, O.A., Binion, D.G., Miura, H., Bosnjak, J.J., Otterson, M.F., Telford, G.L., Gutterman, D.D., Role for Hydrogen Peroxide in Ach-induced Dilation of Human Intestinal Microvessels, FASEB, (accepted. 2004).
75. Theriot, K., Binion, D.G., Thameem, D., Shidham, S., Saeian, K., Hatoum, O. A., Telford, G., Otterson, M.F., Clinical Factors Contributing to Rapid Re-operation for Crohn's Disease, Wisconsin Surgical Society, (accepted, 2004).
76. Theriot, K., Binion, D.G., Thameem, D., Shidham, S., Saeian, K., Hatoum, O. A., Lundeen, S., Telford, G., Otterson, M.F., Rapid Re-operation for Crohn's Disease, Central Surgical Association, (accepted, 2004).
77. Rafiee, P, Theriot, M.E., Otterson, M.F., Binion, D.G., Vascular Endothelial Growth Factor (VEGF) Protects Human Intestinal Microvascular Endothelial Cells (HIMEC) Against Ionizing Radiation Induced Cell Death Via PI3K/akt, Bcl-2 and MAPKs, Gastroenterology, 130:A-516, 2006.
78. Rafiee, P., Horowitz, S., Rogaczewski A., Nelson, V., Kalyanaraman, B., Otterson, M.F., Binion, D.G., Increased Human Intestinal Microvascular Endothelial Arginase Activity Mediated by RHOA Pathway: Mechanisms Underlying IBD Endothelial, Gastroenterology, 130:A-686, 2006.
79. Rafiee, P., Theriot, M.E., Otterson, M.F., Binion, D.G., Vascular Endothelial Growth Factor (VEGF) Activates Signal Transducers and Activators Of Transcription (stats) Proteins in Human Intestinal Microvascular Endothelial Cells (HIMEC), Gastroenterology, 130:A-656, 2006.
80. Rafiee, P., Theriot, M.E., Otterson, M.F., Binion, D.G., Role of Mapk in Activation of Signal Transducers and Activation of Transcription (STATs) Proteins in VEGF Stimulated Human Intestinal Microvascular Endothelial Cells (HIMEC), Gastroenterology, 130:A-686, 2006.
81. Hatoum, O.A., Miura, H., Selle, R.M., Larsen, B.T., Kopelman, D., Otterson, M.F., Gutterman, D.D., Binion, D.G., Beneficial Effect of Mesalamine on Microvascular Dysfunction of Ulcerative Colitis, Gastroenterology, 130:A-698, 2006.
82. Williams, J.B., Weber, L.R., Beaulieu, D.B., Issa, M., Knox, J.F., Emmons, J., Otterson, M.F., Hatoum, O.A., Binion, D.G., Long-Term Infliximab Maintenance Infusion Regimens and Rates of Hospitalization, Surgery and Disability in Crohn's Disease, Gastroenterology, 130:A-143, 2006.
83. Ferrer, V., Otterson, M.F., Lundeen, S., Weber, L.R., Bajaj, J.S., Hatoum, O.A., Binion, D.G., Elevated C-Reactive Protein On Admission Predicts Colectomy in Hospitalized IBD Colitics with and Without Clostridium Difficile Co-Infection, Gastroenterology, 130:A-210, 2006.
84. Ashwathnarayan, R., Weber, L.R., Issa M., Knox, J., Skaros, S., Hatoum, O.A., Emmons, J., Otterson, M.F., Binion, D.G., Azathioprine Intolerant Crohn's Disease Patients: A Clinical Subgroup with Significantly Worse Disease Complications, Severity and Disability, Gastroenterology, 130:A-646, 2006.
85. Issa, M., Skaros, S., Otterson, M.F., Lundeen, S., Weber, L.R., Beaulieu, D.B., Knox, J.F., Binion, D.G., Corticosteroid Dose Influences Colectomy Rate in Hospitalized IBD Patients with Clostridium Difficle, Gastroenterology, 130:A-656, 2006.
86. Issa, M., Skaros, S., Beaulieu, D.B., Weber, L.R., Vijayapal, A.S., Graham, M.B., Knox, J.F., Emmons, J., Hatoum, O.A., Otterson, M.F., Binion, D.G., Increasing Impact of Clostridium difficile on Inflammatory Bowel Disease: A Tertiary Referral Center Experience, Gastroenterology, 130:A-649, 2006.
87. Weber, L.R., Beaulieu, D.B., Emmons, J., Knox, J.F., Otterson, M.F., Issa, M., Skaros, S., Binion, D.G., Successful Infliximab RE-Initiation in a Previously Allergic Crohn's Disease Patient Following Hematopoietic Stem Cell Transplantation (HSCT), Gastroenterology, 130:A-662, 2006.
88. Rogaczewski A., Kexel, P.J., Theriot, M.E., Nelson, V.M., Otterson, M.F., Binion, D.G., Rafiee, P., Sensitization of Human Intestinal Microvascular Endothelial Cells (HIMEC) to Ionizing Radiation By Curcumin, Gastroenterology, 130:A-683, 2006.
89. Horowitz S., Rogaczewski, A., Nelson, V., Lazarova, Z., Andrekopouis, C., Kalyanaraman, B., Otterson, M.F., Binion, D.G., Rafiee, P., Increased Arginase II and Decreased NO Synthesis in Human Microvascular Endothelial Cells (HIMEC) of IBD Patients, Gastroenterology, 130:A-684, 2006.
90. Otterson, M.F., Theriot, K., Binion, D.G., Thameem, D., Shidham, S., Hatoum, O.A., Lundeen, S., Telford, G., Rapid Re-Operation for Crohn's Disease, Gastroenterology, 130:A-856, 2006.
91. Lundeen, S.J., Otterson, M.F., Telford, G.L., Binion, D.G., Peppard, W.J., Clostridium difficile Enteritis: An Early Post-Operative Complication in IBD Patients Following Colectomy, Gastroenterology, 130:A-890, 2006.
92. Ananthakrishnan, A.N., Weber, L.R., Knox, J.F., Skaros, S., Emmons, J, Issa, M., Otterson, M.F., Binion, D.G., Permanent Work Disability in Crohn's Disease, Gastroenterology, 132:A-512, 2007.
93. Arif, M., Weber, L.R., Knox, J.F., Skaros, S., Issa, M., Emmons, J., Lundeen, S., Otterson, M.F., Binion, D.G., Patterns of Proton Pump Inhibitor Use in Inflammatory Bowel Disease (IBD) and Concomitant Risk of Clostridium difficile Infection, Gastroenterology, 132:A-513, 2007.
94. Arif, M., Weber, L.R., Knox, J.F., Skaros, S., Issa, M., Emmons, J., Lundeen, S., Otterson, M.F., Binion, D.G., Incidence and Risk Factors for Thromboembolism in Inflammatory Bowel Disease (IBD), Gastroenterology, 132:A-513, 2007.
95. Arif, M., Weber, L.R., Knox, J.F., Skaros, S., Issa, M., Emmons, J., Lundeen, S., Otterson, M.F., Binion, D.G., Clinical hypertension and Vascular Complications in Inflammatory Bowel Disease (IBD), Gastroenterology, 132:A-516, 2007.
96. Arif, M., Weber, L.R., Knox, J.F., Skaros, S., Issa, M., Emmons, J., Lundeen, S., Otterson, M.F., Binion, D.G., Prevalence and Management of Comorbid Depression in Inflammatory Bowel Disease (IBD), Gastroenterology, 132:A-659, 2007.
97. Issa, M., Weber, L.R., Kanaa,Y., Emmons, J., Skaros, S., Knox, J.F., Lundeen, S., Otterson, M.F., Binion, D.G., Decreasing Rates of Colectomy Despite High Rates of Hospitalization in C. difficile Infected IBD Patients: A Tertiary Referral Center Experience, Gastroenterology, 132:A-663, 2007.
98. Issa, M., Weber, L.R., Skaros, S., Beaulieu, D.M., Emmons, J., Knox, J.F., Otterson, M.F., Binion, D.G., Recurrent Clostridium difficile Colitis in Inflammatory Bowel Disease Patients, Gastroenterology, 132:A-660, 2007.
99. Rajagopal, M., Weber, L.R., Knox, J.F., Skaros, S., Issa, M., Emmons, J., Lundeen, S., Otterson, M.F., Saeian, K., Bajaj, J.S., Binion, D.G., Distinct Phenotypes of Inflammatory Bowel Disease in U.S. Minority Populations: Comparison of African American and Asian Subgroups, Gastroenterology, 132:A-662, 2007.
100. Rafiee, P., Nelson, V.M., Kanaa, Y., Otterson, M.F., Binion, D.G., Induction of Hsp32 by Curcumin rescues Human Intestinal Microvascular Endothelial Cells (HIMEC) from Radiation Induced Apoptosis, Gastroenterology, 132:A-570, 2007.
101. Otterson, M.F., Binion, D.G., Nelson, V.M., Floer, M., Kanaa, Y., Rafiee, P., Curcumin sensitizes Human Intestinal Microvascular Endothelial Cells (HIMEC) to Ionizing Radiation by Targeting mTOR and Akt, Gastroenterology, 132:A-367, 2007.
102. Jorns, J., Otterson, M.F., Binion, D.G., Hyun, B.L., Komorowski, R., Correlation of histology with medical treatment of Crohn's disease, Society for Surgery of the Alimentary Tract (accepted, 2007).
103. Beaulieu, D.B., Mulcaire-Jones, M., Issa, M., Ananthakrishnan, A.N., Knox, J.F., Skaros, S., Lemke, K., Bajaj, J.S., Binion, D.G., Otterson, M.F., Markers of Inflammation in Women with Crohn's Disease During Pregnancy, Gastroenterology, 134:A-199, 2008.
104. Sun, N., Katz, J.A., Issa, M., Knox, J.F., Skaros, S., Otterson, M.F., Binion, D.G., Clinical Course of Crohn's Disease Following Lymphoma Treatment, Gastroenterology, 134:A-347, 2008.
105. Rafiee, P., Otterson, M.F., Binion, D.G., Curcumin Inhibits Angiogenesis of Human Intestinal Microvascular Endothelial Cells (HIMEC) Through COX-2 Inhibition, Gastroenterology, 134:A-217, 2008.
106. Berger, W., White, K.T., Benes, P.S., Walsh, B.A., Hastings, J., Berman, J.E., Sultana, R., Hoffmann, R.G. Otterson, M.F., Bowel Dysfunction in Spinal Cord Injury Correlates with Inpatient Utilization and Survival, Gastroenterology, 134:A-327, 2008.
107. Arif, M., Ananthakrishnan, A.N., Beaulieu, D.B., Issa, M., Skaros, S., Knox, J.F., Lemke, K., Lundeen, S.J., Otterson, M.F., Binion, D.G., Clinical Factors Contributing to Thromboembolic Complications in Patients with Inflammatory Bowel Disease, Gastroenterology, 134:A-350, 2008.
108. Ananthakrishnan, A.N., Issa, M., Beaulieu, D.B., Skaros, S. Knox, J.F., Lemke, K. Emmons, J., Lundeen, S.J., Otterson, M.F., Binion, D.G., History of Medical Hospitalization Predicts Future Need for Colectomy in Patients with Ulcerative Colitis, Gastroenterology, 134:A-352, 2008.
109. Issa, M., Ananthakrishnan, A.N., Beaulieu, D.B., Knox, J.F., Skaros, S. Lemke, K. Emmons, J., Lundeen, S.J., Otterson, M.F., Binion, D.G., Association Between Vitamin B12 Levels and Colectomy in Ulcerative Colitis, Gastroenterology, 134:A-505, 2008.
110. Beaulieu, D.B., Mulcaire-Jones, M., Ananthakrishnan, A.N., Issa, M., Knox, J.F., Skaros, S., Lemke, K., Bajaj, J.S., Otterson, M.F., Binion, D.G., Increasing Crohn's Disease Severity Over Time: Correlating Interval to First Surgery with Decade of Diagnosis, Gastroenterology, 134:A-504, 2008.
111. Stein, D., Issa, M., Skaros, S., Knox, J.F., Lemke, K., Emmons, J., Otterson, M.F., Ananthakrishnan, A.N., Binion, D.G., History of Interrupted Infliximab Dosing Significantly Diminishes Efficacy During Long-Term Maintenance Therapy in Crohn's Disease, Gastroenterology, 134:A-666, 2008.
112. Floer, M., Binion, D.G., Nelson, V.M., Manley, S., Wellner, M., Sadeghi, S.N., Sewell, C.I., Otterson, M.F., Kucharzik, T., Rafiee, P., Increased Expression of Muts Homologue 2 (MSH2) in Crohn's Disease Intestinal Strictures Is Linked to Increased Proliferative Capacity of Muscularis Mucosa Myofibroblasts, Gastroenterology, 134:A-157, 2008.
113. Kane, D., Biller, J., Otterson M.F., GI Tract Operations in Adult CF Patients: A Diverse Spectrum of Findings, Accepted, Wisconsin Surgical Society, 2008.
114. Darouiche, R.. *(1), Wall, M.(2), Itani, K. (3), Berger, D. (4), Otterson, M.F. (5), Webb, A. (6), Crosby, C. (7), AlSharif, A. (8)A Prospective, Randomized, Multicenter Clinical Trial of Chloraprep versus Povidone-Iodine for Prevention of Surgical Site Infection, (1)Infectious Disease, Michael E. Debakey Veterans Affairs Medical Center, (2)Surgery, Ben Taub General Hospital, Houston, (3)Surgery, Veterans Affairs Medical Center, Boston, (4)Surgery, Michael E. Debakey Veterans Affairs Medical Center, Houston, (5)Surgery, Medical College of Wisconsin, Milwaukee, (6)Surgery, Veterans Affairs Medical Center, Atlanta, (7)Medical Affairs, Enturia, Leawood, (8)Medicine, Baylor College of Medicine, Houston, United States, International College of Surgeons, accepted, 2008.
115. Otterson, M.F., Leming, S., Callison, J., Moulder, J.E., NMDA Receptor Antagonists Block but do not Mitigate Prodromal Radiation Sickness, Radiation Research Society, 2009.
116. Rafiee P, Nelson V, Baker J, Otterson MF, Binion DG. Ionizing Radiation Modulates Hsp34 and beta-Catenin. FASEB. A42: (1120.18). 2008.
117. Stein, D.. Ananthakrishnan, A., Ulitsky, A., Naik, A., Marn, C., Sudakoff, G., Otterson, M.F., Perera, L., Binion, D.G., Issa, M., Pre-operative small bowel follow through detects more Crohn's disease strictures than CT enterography: Comparison with Intra-operative Findings, American College of Gastroenterology, accepted, 2009.
118. Rafiee, P., Nelson, V., Baker, J., Otterson, M.F., Binion, D.G.. Effect of Radiation on Human Intestinal Microvascular Cells (HIMEC): Role of Akt/m TOR and NFkappa B. FASEB. (accepted 2010).
119. Simvastatin enhances eNOS Expression in Human Intestinal Microvascular Endothelial Cells: Improvement in Crohn's disease Endothelial dysfunction Manley, S., Binion, D.G., Stein, D.J., Otterson, M.F., Raifiee, P., AGA, (accepted , 2010)
120. Otterson, M.F., Leming, S., Callison, J., Moulder, J.E., Gastrointestinal Motility Effects of Radiation differ with Dose Rate of Radiation Exposure, AGA, (accepted , 2010)
121. Naik, A.S., Zadvornova, Y., Lundeen, S.J., Stein, D.J., Venu, N., Otterson, M.F., Issa, M., Perera, L.P., Abdominal venous thrombosis following inflammatory bowel disease related surgeries while on dalteparin prophylaxis. Case series. Accepted, 2011, DDW.
122. Ridolfi, T., Watch, L., Brown, K, Seabrook, G., Foley, D., Otterson, M.F., Iliac Artery Dissection Followed by Rectal Perforation: A Possible Correlation in Vascular Ehlers Danlos Syndrome, Wisconsin Surgical Society, (Accepted, 2011).
123. Link, B.J., Medda, R., Nie, L., Schmidt, J.L., Jovanovic, N., Otterson, M.F., Rafiee, P., Black Raspberry Powder Inhibits IL-8-Mediated Angiogenesis in Human Intestinal Microvascular Endothelial Cells Role of; MAPK, Bcl2, Akt and COX-2. (FASEB, Submitted, 2011).
124. Timing of Pre-Operative Anti-Tumor Necrosis Factor Therapy Does Not Affect Early Post-Operative Complication Rates in Inflammatory Bowel Disease Patients Undergoing Intestinal Resection. (AGA, Accepted, 2012, Poster of Distinction).
125. Bautista, M., Zadvornova, Y., Eastwood, D., Naik,A.S., Stein, D.J., Venu, N., Ludwig, K., Kosinski, L., Otterson, M.F., Perera, L.P., Surgical Outcomes in the Elderly with Inflammatory Bowel Disease. (AGA, Accepted, 2012).
126. Link, B.J., Medda, R., Nie, L., Schmidt, J.L., Jovanovic, N., Otterson, M.F., Rafiee, P., Anti-Inflammatory Effect of Black Raspberry Extract on Human Intestinal Microvascular Endothelial Cells (HIMEC). (AGA, Accepted, 2012).
127. Stein D.J., Zadvornova, Y, Lin, E, Naik, A, Perera, L, Venu, N, Otterson, M.F., Binion,D.G., Long-term clinical outcomes following surgery in Crohn’s disease patients on combination immunosuppression: Impact of anastomotic reconstruction on quality of life and healthcare utilization, (AGA, Accepted, 2013).
128. Longo, J.M., Siker, M.L., George, B, Kosinski, L., Ludwig, K.A., Otterson, M.F., Thomas, J.P., Wiebe, L.A., Erickson, B., Helical Tomotherapy with Concurrent Chemotherapy in the Treatment of Anal Canal Carcinoma: A Review of Clinical Outcomes at a Tertiary Referral Center, 2014 Gastrointestinal Cancers Symposium, American Society for Clinical Oncology (ASCO, Submitted, 2013)
129. Berger, W., Otterson, M.F., White, Walsh, B., Berman, Williams, Leming, S., Does Percutaneous Endoscopic Colostomy Help in Spinal Cord Injury Bowel dysfunction? , (AGA, Accepted, 2015).
130. Longo, J.M., Siker, M.L., George, B, Kosinski, L., Ludwig, K.A., Otterson, M.F., Thomas, J.P., Wiebe, L.A., Petersen, C., Ridolfi, T., Erickson, B., Image based helical tomotherapy with concurrent chemotherapy in the treatment of anal canal carcinoma: a single institution series, (ASCO, Submitted, 2015)

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