CURRICULUM VITAE
Robert L. Truitt PhD
Robert L. Truitt PhD
Emeritus Professor
Department of Pediatrics
Division of Pediatrics Hematology Oncology Blood and Marrow Transplant
Department of Pediatrics
Division of Pediatrics Hematology Oncology Blood and Marrow Transplant
OFFICE ADDRESS: |
8701 Watertown Plank Road |
Milwaukee, WI 53226 |
EDUCATION: |
1964 - 06/1968 BA - Microbiology, Southern Illinois University, Carbondale, IL |
1968 - 06/1973 PhD - Microbiology, Southern Illinois University, Carbondale, IL |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
1972 - 1974 Postdoctoral Fellow, Lobund Laboratory, University of Notre Dame, Notre Dame, IN |
1974 - 1975 Postdoctoral Fellow, Winter Research Laboratory, Mount Sinai Medical Center, Milwaukee, WI |
FACULTY APPOINTMENTS: |
1975 - 1977 Research Associate, Winter Research Laboratory, Mount Sinai Medical Center, Milwaukee, WI |
1977 - 1983 Senior Scientist, Winter Research Laboratory, Mount Sinai Medical Center, Milwaukee, WI |
1983 - 1984 Associate Scientist, Department of Medicine, Milwaukee Clinical Campus, University of Wisconsin Medical School, Milwaukee, WI |
1983 - 1984 Associate Director, Winter Research Laboratory, Mount Sinai Medical Center, Milwaukee, WI |
1984 - 1988 Research Associate Professor, Dept. of Pediatrics, Medical College of Wisconsin, Milwaukee, WI |
1988 - 1991 Research Professor, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI |
1991 - 2010 Professor of Immunology with Tenure, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI |
1997 - 2010 Professor, Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI |
2002 - 2009 Senior Investigator, Blood Research Institute, Blood Center of Southeastern Wisconsin, Milwaukee, WI |
2010 - Present Emeritus Professor of Pediatrics, Medical College of Wisconsin, Milwaukee, WI |
HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS: |
1985 - 1990 Director, Immunology/Transplantation Program, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
1985 - Present Full Member, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
1985 - 1998 Doctorate Staff, Hematology Section, Children's Hospital of Wisconsin, Milwaukee, WI |
1988 - 2001 Coordinator, FACScan Flow Cytometry Shared Facility, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
1992 - 1995 Research Coordinator, Biological Response Modifiers Program, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
1998 - 2001 Co-Leader, Bone Marrow Transplantation Program, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
1998 - 1999 Associate Director for Planning, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
2001 - 2008 Program Director, Experimental BMT and Immunotherapy Program, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
2002 - 2007 Associate Director, Basic Science Research, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
2008 - 2009 Program Co-Director, Blood & Marrow Transplant Program, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
2008 - 2009 Associate Director of Research, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
2010 - Present Associate Director of Research Resources, Cancer Center, Medical College of Wisconsin, Milwaukee, WI |
AWARDS AND HONORS: |
1972 - 1973 Postdoctoral Fellowship, United Cancer Council |
1973 - 1975 Damon Runyon Memorial Fund , Cancer Research Postdoctoral Fellowship |
1976 - 1978 Special Fellow Award, Leukemia Society of America |
1978 - 1983 Scholar Award, Leukemia Society of America |
2007 Distinguished Service Award, Medical College of Wisconsin |
2009 Health Care Heroes Award, BizTimes-Milwaukee for advancements in health care in pediatric oncology |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
1972 American Society for Microbiology (Member) |
1974 Association for Gnotobiotics (Member ) |
1975 International Society of Experimental Hematology (Member ) |
1976 American Association of Immunologists (Member ) |
1980 American Association for the Advancement of Science (Member ) |
1980 - 1981 Association for Gnotobiotics (Vice-President ) |
1980 - 1983 Association for Gnotobiotics (Board of Directors ) |
1981 - 1982 Association for Gnotobiotics (President ) |
1984 International Association for Gnotobiotics (Member ) |
1985 Pediatric Oncology Group/Children’s Oncology Group (Member) |
1991 - 1993 Association for Gnotobiotics (Board of Directors ) |
2001 American Society of Hematology (Member ) |
2001 Great Lakes International Imaging and Flow Cytometry Association (Member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
1989 T-cell depletion in allogeneic bone marrow transplantation: Progress and problems. Haematologica 74:235-248 |
2003 Targeting DCs to Induce Regulatory T-cells In Vivo. Commentary - Inside Blood, Blood, 101: 4649-4650 |
Editorial Board |
1995 - Present Biology of Blood and Marrow Transplantation |
Journal Review |
Journal of Interferon Research |
Clinical Cancer Research |
Bone Marrow Transplantation |
Journal of Immunology |
Experimental Hematology |
Transplantation |
Transfusion Medicine |
Journal of Clinical Investigations |
Cancer Immunology & Immunotherapy |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
1986 - 1990 Member, Board of Trustees, Wisconsin Chapter of the Leukemia Society of America, Inc. |
1991 - 1995 Member, Board of Trustees, Wisconsin Chapter of the Leukemia Society of America, Inc. |
1999 - Present Member, Scientific Committee, Wisconsin Breast Cancer Showhouse for a Cure |
2001 Member, Steering Committee, Great Lakes International Imaging and Flow Cytometry Association |
03/2003 Member, Cancer Center Community Advisory Board, Medical College of Wisconsin |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
1978 Site Visitor, Division of Cancer Research Resources and Centers, NCI |
1983 Special Reviewer, Experimental Immunology Study Section, NIH |
1984 - 1990 Member, Nominating Committee, International Association for Gnotobiotics |
1987 Member, Experimental Immunology Ad Hoc Study Sections, NIH |
1987 Site Visitor, Program Project Grant Reviews, NCI |
1988 Site Visitor, Program Project Grant Reviews, NCI |
1988 Member, Bone Marrow Transplant Ideas and Planning Committee, Pediatric Oncology Group |
1988 Chair, Program Project Grant Reviews, NCI |
1989 Chair, Program Project Grant Reviews, NCI |
1990 Member, Experimental Immunology Ad Hoc Study Sections, NIH |
1990 Consultant to Pediatric Branch, Neuroblastoma Immunotherapy Protocol, NCI |
1991 Chair, Program Project Grant Reviews, NCI |
1992 Chair, Program Project Grant Reviews, NCI |
1992 Member, Experimental Immunology Ad Hoc Study Sections, NIH |
1992 Ad Hoc Member, Subcommittee F - Cancer Research Manpower, NCI |
1993 Site Visitor, Division of Cancer Research Resources and Centers, NCI |
1993 - 1996 Full member, Subcommittee F - Cancer Research Manpower, NCI |
1994 - 1996 Member, Tumor Immunology Scientific Subcommittee, American Society for Blood and Marrow Transplantation |
1995 Chair, Program Project Grant Reviews, NCI |
1996 Member, Ad Hoc Committee, T32 Application |
1996 Chair, Program Project Grant Reviews, NCI |
1996 - 1998 Ad Hoc Member, Subcommittee D - Clinical Program Projects Review Group, NCI |
1996 Member, Ad Hoc Committee, Minority K08 Applications |
1997 Chair, Program Project Grant Reviews, NCI |
02/1998 Ad Hoc Member, Subcommittee F - Cancer Research Manpower, NCI |
07/1998 - 06/1999 Special Reviewer, Experimental Therapeutics II (ET-2) IRG, NIH |
1998 Chair, Program Project Grant Reviews, NCI |
06/1999 Special Reviewer, Experimental Therapeutics II (ET-2) IRG, NIH |
11/1999 Ad Hoc Reviewer, Subcommittee G - Education, NCI |
1999 Chair, Program Project Grant Reviews, NCI |
1999 Member, Subcommittee G - Education, NCI |
1999 Teleconference Review, Subcommittee D - Clinical Program Projects Review Group, NCI |
06/2000 Ad Hoc Member, Subcommittee F - Cancer Research Manpower, NCI |
06/2000 Ad Hoc Reviewer, Subcommittee G - Education, NCI |
2000 Chair, Program Project Grant Reviews, NCI |
2000 Member, Subcommittee G - Education, NCI |
2000 - 2007 Member, External Advisory Committee, University of Kentucky’s Program Project Grant on “Growth, Regulation and Therapy of Leukemia and Lymphoma” |
2001 Chair, Program Project Grant Reviews, NCI |
2001 Study Section Boundary Team, Center for Scientific Review’s Oncological Sciences, NIH |
2001 Intramural Review, Experimental Immunology Branch, National Cancer Institute, NIH |
06/2002 Ad Hoc Member, Subcommittee F - Cancer Research Manpower, NCI |
11/2002 Ad Hoc Member, Subcommittee F - Cancer Research Manpower, NCI |
2002 Chair, Program Project Grant Reviews, NCI |
2002 External Scientific Advisor, External Review Panel, IBMTR/ABMTR |
2002 Ad Hoc Member, Subcommittee D - Clinical Program Projects Review Group, NCI |
2003 Reviewer, Loan Repayment Program, NIH |
2003 Special Emphasis Panel, Experimental Therapeutics-II Study Section, NIH |
2003 Ad hoc, Project Grant Review, NHLBI Program |
2004 - 2007 Member, Elected to Board of Directors, American Society for Blood and Marrow Transplantation |
2004 Ad hoc, Project Grant Review, NHLBI Program |
2004 Reviewer, Loan Repayment Program, NIH |
2004 Intramural Review, Experimental Transplantation and Immunology Branch, NIH |
2004 - 2007 Member, Membership Committee, American Society for Blood and Marrow Transplantation |
2005 Reviewer, Loan Repayment Program, NIH |
2005 Member, Project Grants on Hematopoietic Stem Cell Transplantation, NCI Cluster Reviews for Program |
2005 Member, Scientific Peer Review Committee (Immunotherapy), DOD Breast Cancer Research Program |
2005 - 2006 Ad Hoc Member, Subcommittee D - Clinical Program Projects Review Group, NCI |
2005 Member, NCRR Special Emphasis Panel, Centers of Biomedical Research Excellence |
2006 - 2007 Chairperson, Membership Committee, American Society for Blood and Marrow Transplantation |
2006 Discussion Leader and Reviewer, Special Emphasis Panel, NCI Clinical Sciences |
2006 Member, Project Grants on Hematopoietic Stem Cell Transplantation, NCI Cluster Reviews for Program |
2006 Ad hoc member, Study Section, NIH Center for Scientific Review “Transplatation, Tolerance and Tumor Biology” |
2007 Founding Chairperson, Distance Learning Committee, American Society for Blood and Marrow Transplantation |
2007 Reviewer, Loan Repayment Program, NIH |
2007 Reviewer, NCI Special Emphasis Panel, Program Project Grant from FHCRC |
2007 Member, NHLBI Program Project Special Review Committee, Dana-Farber Cancer Institute |
2007 Ad hoc member, Study Section, NIH Center for Scientific Review “Transplatation, Tolerance and Tumor Biology” |
2007 - Present Member, Distance Learning Committee, American Society for Blood and Marrow Transplantation |
05/2008 - 10/2008 Reviewer, Oncology Fellowship (F09) Program, NIH Center for Scientific Review |
2008 Reviewer, NCI Special Emphasis Panel, Program Project Grant from FHCRC |
2008 Member, 1 Peer Review Committee, CDMRP Breast Cancer Research Program – Idea |
2008 Ad Hoc Member, Subcommittee D - Clinical Program Projects Review Group, NCI |
2008 Reviewer, Loan Repayment Program, NIH |
2008 Ad hoc, Project Grant Review, NHLBI Program |
2008 Member, NHLBI Program Project Special Review Committee, Dana-Farber Cancer Institute |
06/2009 Reviewer, Oncology Fellowship (F09) Program, NIH Center for Scientific Review |
2009 Teleconference Review, Subcommittee D - Clinical Program Projects Review Group, NCI |
2009 Ad hoc, Project Grant Review, NHLBI Program |
2009 Reviewer, Loan Repayment Program, NIH |
02/2010 Reviewer, Oncology Fellowship (F09) Program, NIH Center for Scientific Review |
10/2010 Reviewer, Oncology Fellowship (F09) Program, NIH Center for Scientific Review |
2010 Member, Peer Review Committee, CDMRP Breast Cancer Research Program |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
Japanese Society of Bone Marrow Transplantation, Fourteenth Annual Meeting, Sapporo, Japan, 12/1991 |
Initiation and Maintenance of Tumor Dormancy, Workshop on Cellular Immune Mechanisms, Ottawa, Ontario, 1991 |
Workshop Presentation, American Association for Cancer Research, Toronto, Canada, 1995 |
Memorial University, St. Johns, Newfoundland, Canada, 1996 |
Regulatory/Suppressive T Cells, Keystone Conference, Banff, Alberta, Canada, 2004 |
National |
Scientific Program Advisory Committee, XIVth International Symposium for Comparative Research on Leukemia and Related Diseases, Vail, CO, 10/08/1989 - 10/12/1989 |
Use of Interleukin-2 in Hematologic Malignancies, NCI-INSERM Workshop, Bethesda, MD, 1991 |
Emory University, Atlanta, GA, 1992 |
Society for Biological Therapy, 8th Annual Meeting, Nashville, TN, 1993 |
Cellular Immunity and the Immunotherapy of Cancer, Taos, NM, 1993 |
BMT: Basic and Clinical Research Studies, National Heart, Lung, and Blood Institute, Workshop on GVH Disease and Other Immunologic Complications of Unrelated-Donor, Bethesda, MD, 03/10/1994 - 03/11/1994 |
American Society for Histocompatibility and Immunogenetics, Pittsburgh, PA, 10/1994 |
American Society of Hematology, Nashville, TN, 12/1994 |
BMT Program, National Heart, Lung and Blood Institute, Bethesda, MD, 1994 |
Advances and Controversies in Bone Marrow Transplantation, Keystone, CO, 1994 |
American Society of Blood and Marrow Transplantation, Keystone, CO, 01/1995 |
Workshop Presentation, American Society for Histocompatibility and Immunogenetics, Dallas, TX, 10/1995 |
Blood Cell and Bone Marrow Transplants, Keystone Symposium, Keystone, CO, 01/15/1996 - 01/21/1996 |
American Society for Blood and Marrow Transplantation, San Diego, CA, 1996 |
Department of Microbiology and Immunology, University of North Dakota, Grand Forks, ND, 1996 |
American Society for Histocompatibility and Immunogenetics, Regional Meeting, Hilton Head, SC, 03/1997 |
Transplantation Society, Fifth Basic Sciences Symposium, Chautauqua, NY, 1997 |
American Society for Hematology, Miami Beach, FL, 1998 |
Preclinical Models of GVL Reactivity, American Society for Blood and Marrow Transplantation, Anaheim, CA, 03/29/2000 - 04/01/2000 |
Animal Models in GVL, American Society for Blood and Marrow Transplantation, Anaheim, CA, 03/2000 |
Oral Session Co-chair: Experimental BMT: Novel Approaches to Optimize GVL/GVT Responses, American Society of Hematology, San Francisco, CA, 12/2000 |
American Society for Hematology, Annual Meeting, San Francisco, CA, 12/2000 |
Cellular Immunity and Immunotherapy of Cancer, Keystone Symposium, Santa Fe, NM, 2000 |
Women for MACC, 11/2003 |
Immune Tolerance, Keystone Symposium, Snowbird, UT, 2003 |
ASBMT/IBMTR, Tandem Meeting, Keystone, CO, 2003 |
Mortimer M. Bortin Lecture, Tandem BMT Meeting, Orlando, FL, 02/2004 |
University of Wisconsin Comprehensive Cancer Center, Oncology Grand Rounds, Madison, WI, 2005 |
University Club, 10/2006 |
Opportunities for PhDs in Hematology Research, American Society for Hematology Annual Meeting, San Francisco, CA, 2008 |
Mechanisms of Funding for PhDs, Trainee Day, American Society for Hematology Annual Meeting, New Orleans, LA, 2009 |
Regional |
Gnotobiology, VIII International Symposium, University of Notre Dame, Notre Dame, IN, 06/18/1984 - 06/22/1984 |
IBMTR Participating Teams, First Annual Meeting, Providence, RI, 07/1992 |
Bone Marrow Transplantation, Keystone, CO, 1992 |
22nd Annual, Autumn Immunology Conference, Chicago, IL, 1993 |
American Society of Pediatric Hematology/Oncology, Chicago, IL, 10/1994 |
Cancer Center, University of Minnesota Medical School, Minneapolis, MN, 1995 |
Bone Marrow Transplantation Program, Northwestern University, Evanston, IL, 1996 |
Midwest Division of the American Cancer Society, Dubuque, IA, 10/1999 |
American Society for Blood and Marrow Transplantation, Keystone, CO, 1999 |
Great Lakes International Imaging and Flow Cytometry Association, 10th Annual Meeting, 10/12/2001 - 10/14/2001 |
Local |
Alien Histocompatibility Antigens on Cancer Cells, First International Symposium, Wingspread Conference Center, Racine, WI, 05/20/1979 - 05/22/1979 |
Alien Histocompatibility Antigens in Cancer, Second International Symposium, Wingspread Conference Center, Racine, WI, 10/08/1980 - 10/11/1980 |
Cellular Immunotherapy of Cancer, International Symposium, Wingspread Conference Center, Racine, WI, 10/30/1986 - 11/01/1986 |
Co-organizer, Workshop on Use of Flow Cytometry in Clinical Medicine, Medical College of Wisconsin, Milwaukee, WI , WI, 11/08/1986 |
Scientific Program Committee, Sixth Annual Marquette Life Sciences Symposium, Milwaukee, WI, 03/17/1989 - 03/18/1989 |
Frontiers in Cancer Biology, Scientific Program Committee, MCW Cancer Center, 04/06/1991 |
Association for Gnotobiotics, Madison, WI, 1992 |
Association for Gnotobiotics, 30th Annual Meeting, Madison, WI, 1992 |
Wisconsin-American Cancer Society, Annual Dinner, 04/2000 |
Waukesha Rotary Club, 05/2003 |
Cancer Media Day, Medical College of Wisconsin, Milwaukee, WI, 11/2003 |
American Cancer Society, Donor Recognition Dinner, 05/2004 |
Crystal Ball, American Cancer Society, 05/2007 |
First MACC Fund, Scientific Symposium, Milwaukee, WI, 06/19/2007 |
Second MACC Fund, Scientific Symposium, Madison, WI, 12/16/2009 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
1985 - 1990 Member, Cancer Center Executive Committee, Medical College of Wisconsin |
1987 - 1994 Member, Flow Cytometry Oversight Committee, Cancer Center, Medical College of Wisconsin |
1988 - Present Member, Promotions Committee, Department of Pediatrics, Medical College of Wisconsin |
1990 - Present Chairman, Research Grants Committee, Cancer Center, Medical College of Wisconsin |
1990 - 1992 Elected, Cancer Center Executive Committee, Medical College of Wisconsin |
1991 Chairman, Flow Cytometry Oversight Committee, Cancer Center, Medical College of Wisconsin |
1992 - 1994 Member, Cancer Education Committee, Cancer Center, Medical College of Wisconsin |
1993 - 1994 Member, Cancer Center Executive Committee, Medical College of Wisconsin |
1994 - 1995 Chairperson, Taskforce on Responsible Conduct of Research, Department of Pediatrics, Medical College of Wisconsin |
1994 Member, Planning Committee, Cancer Center, Medical College of Wisconsin |
1994 - 2000 Member, Research Committee, Department of Pediatrics, Medical College of Wisconsin |
1994 - 2000 Member, Research Strategic Advisory Committee, Cancer Center Research Advisory Group, Medical College of Wisconsin |
1995 - 2000 Member, Shared Facilities Oversight Committee, Medical College of Wisconsin |
1997 Member, 25th Anniversary Celebration Committee, IBMTR |
1998 Planning Director, Planning Committee, Cancer Center, Medical College of Wisconsin |
1999 - 2000 Member, Director Search Committee, Cancer Center, Medical College of Wisconsin |
1999 - 2000 Member, Onc Chief Search Committee, Division of Hem, Department of Medicine, Medical College of Wisconsin |
1999 Member, Chief Search Committee, Division of Urology, Department of Surgery, Medical College of Wisconsin |
1999 - 2000 Vice Chair, Basic Research, Department of Pediatrics, Medical College of Wisconsin |
2000 - Present Chair, Oversight Committee, Flow Cytometry Core Facility, Medical College of Wisconsin |
2001 - 2004 Chair, Search Committee, Department of Biochemistry, Medical College of Wisconsin |
2002 - 2004 Chair, Core Facilities Committee, Medical College of Wisconsin |
2003 - 2004 Member, Planning Task Force, Cancer Center, Medical College of Wisconsin |
2003 Member, Scientific Protocol Review Committee, Cancer Center, Medical College of Wisconsin |
2004 - 2005 Member, Search Committee for Associate Director, Human Molecule Genetics Center, Medical College of Wisconsin |
2005 Member, Basic Science Research Task Force, Children’s Research Institute, Department of Pediatrics, Medical College of Wisconsin |
2005 - Present Member, Search Committee for Cancer Center Director, Cancer Center, Medical College of Wisconsin |
2007 Member, Advancing a Healthier Wisconsin Focus Group, Medical College of Wisconsin |
2007 - Present Member, Search Committee for Chair of Dermatology, Medical College of Wisconsin |
2007 - Present Member, Core Facilities Committee, Medical College of Wisconsin |
2007 - Present Chair, Biophotonic Imaging Core Oversight Committee, Medical College of Wisconsin |
2009 Member, Search Committee, Chief of Surgical Oncology, Medical College of Wisconsin |
2009 - Present Member, Steering Committee, Biospecimen Resource Center, Medical College of Wisconsin |
Hospital |
1985 - 2006 Member, Institutional Review Board/Human Rights Review Committee, Children's Hospital of Wisconsin |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
1986 - 1998 Preceptor for Summer Medical Students |
1987 - 2009 Lectures on cellular immunology and transplantation immunology, Medical Microbiology course, Department of Microbiology |
12/16/1994 Pediatric Grand Rounds, "Graft-vs-Leukemia Effects" |
1995 Cellular and Molecular Immunology, Micro 234: Lectures on Transplantation Immunology |
1995 Midwest Children's Cancer Center Research Presentations |
1996 Midwest Children's Cancer Center Research Presentations |
1997 Cellular and Molecular Immunology, Micro 234: Lectures on Transplantation Immunology |
1997 Grant Writing Seminar: “NIH Grants: a reviewer’s perspective”, Department of Pediatrics |
04/1998 Allergy and Immunology Division Grant Rounds |
1998 - 2000 Panel Participant-MCW graduate course on Ethics and Integrity in Science |
1999 Cellular and Molecular Immunology, Micro 234: Lectures on Transplantation Immunology |
1999 Interdisciplinary Graduate Program Faculty Lectures |
10/2001 Clinical Research Scholars Program Lecture |
2001 Cellular and Molecular Immunology, Micro 234: Lectures on Transplantation Immunology |
2001 Preceptor for Summer Medical Students |
04/2002 Allergy and Immunology Division Grant Rounds |
07/2002 Pediatric Academic Conference |
2004 Cellular and Molecular Immunology, Micro 234: Lectures on Transplantation Immunology |
03/2005 Allergy and Immunology Grand Rounds |
10/2005 Lecturer, Advanced Cell Biology Graduate Course on Stem Cell Biology |
03/2006 Pediatric Grand Rounds, “Regulatory T Cells: The New Immunosuppression” |
2007 - 2009 Panel Participant-MCW graduate course on Ethics and Integrity in Science |
2007 Cellular and Molecular Immunology, Micro 234: Lectures on Transplantation Immunology |
11/2008 - 01/2008 Lecture on “Bioluminescent/Fluorescent Imaging” for Pharmacology 07243: Analytical Methods in Pharmacology and Toxicology |
2009 Cellular and Molecular Immunology, Micro 234: Lectures on Transplantation Immunology |
08/2010 Lecture on “Bioluminescent/Fluorescent Imaging” for Pharmacology 07243: Analytical Methods in Pharmacology and Toxicology |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Undergraduate Students |
1994 Malaka Jackson, Minority Student Research Program, Medical College of Wisconsin |
1995 Crystal Ruffin, Minority Student Research Program, Medical College of Wisconsin |
1997 Chenoa Parsons, Minority Student Research Program, Medical College of Wisconsin |
1999 Elizabeth Hernandez, Minority Student Research Program, Medical College of Wisconsin |
Medical Students |
1986 Prakash Shah, Ph.D., Medical College of Wisconsin |
1987 Jan Jeske, Medical College of Wisconsin |
1991 - 1993 Michael Weiler, Medical College of Wisconsin |
1993 - 1994 Cathleen McCabe, Recipient of 1996 Armand J. Quick Award for Outstanding Senior Medical Student in Biochemistry, Medical College of Wisconsin |
2001 Paul Jeppsen, Medical College of Wisconsin |
Graduate Students |
MS Committees |
1987 - 1992 Jeanette Bjerke, Department of Microbiology, Medical College of Wisconsin |
1993 - 1997 Geri Lyons, Department of Microbiology & Molecular Genetics, Medical College of Wisconsin |
1993 - 1995 Jon D'Cunha, Department of Microbiology & Molecular Genetics, Medical College of Wisconsin |
2002 Lianne Marks, Department of Microbiology & Molecular Genetics, Medical College of Wisconsin |
2005 - 2009 Lance Relland, Department of Microbiology & Molecular Genetics, Medical College of Wisconsin |
2005 - 2009 Eric Kohler, Department of Microbiology & Molecular Genetics, Medical College of Wisconsin |
PhD Students Advised |
1997 - 2001 James LaBelle, MD, PhD, Medical College of Wisconsin |
MS Students Advised |
1998 Michael Rosenblum, Medical College of Wisconsin |
1999 Kelli Rose, Interdisciplinary Graduate Program, Medical College of Wisconsin |
PhD Committees |
2000 - 2003 Michael Rosenblum, MD, PhD, Department of Microbiology & Molecular Genetics, Medical College of Wisconsin |
Postdoctoral Researchers |
1988 - 1990 William Drobyski, M.D., Professor, Department of Medicine, Medical College of Wisconsin |
1989 - 1992 Bryon Johnson, Ph.D., Associate Professor, Department of Pediatrics, Medical College of Wisconsin |
2001 - 2005 Jeffrey Woodliff, Ph.D., Assistant Professor, Department of Pediatrics, Medical College of Wisconsin |
Faculty |
10/1991 - 09/1996 William R. Drobyski, M.D., National Cancer Institute K08-CA01534, “Molecular detection of leukemia after allogeneic BMT”, Medical College of Wisconsin |
03/1998 - 02/2001 Steven Ahrendt, M.D., National Cancer Institute K08-CA76452, “Molecular staging and screening of lung cancer”, Medical College of Wisconsin |
12/1998 - 11/2003 David A. Margolis, M.D., National Cancer Institute K08-CA77330, “Molecular and cellular analysis of T-cells during DLI”, Medical College of Wisconsin |
2001 - 2005 Subra Kuagthasan, M.D., NIH K23 Award, “Characterization of Gut Mucosal T-cells in Children with Crohn’s Disease”, Medical College of Wisconsin |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
High School Students |
2003 - 2004 Benjamin Boxer, Participant in International Science and Engineering Fair |
Medical Students |
1988 - 1989 Ayse Atasoylu, Transitional Year Internship, Cambridge Health Alliance, Harvard Medical School |
Graduate Students |
PhD Students Advised |
1981 - 1984 Chiu-Yang Shih, Ph.D., Marquette University |
Postdoctoral Researchers |
1981 - 1983 Ann V. LeFever, Ph.D., Present position - Director, Immunotherapy Program, St. Luke's Medical Center |
1985 - 1986 Chiu-Yang Shih, Ph.D., Research Section Head, San Diego, CA, PharMingen |
1994 - 1996 Nina A. Garlie, Ph.D., Immunotherapy Program, St. Luke's Medical Center |
2003 - 2007 Michael Rosenblum, Ph.D., Dermatology Residency and Fellowship, University of California - San Francisco |
2007 - 2009 Cheryl Cameron, M.D., Pediatric Hematology/Oncology/Transplant Fellow, Children’s Hospital of Wisconsin |
AD HOC GRANT REVIEWS: |
2003 Veteran's Administration; Netherlands Cancer Foundation (Stichting Koningin Wilhelmina Fonds); National Foundation - March of Dimes; United States-Israel Binational Science Foundation; North Carolina Board of Science and Technology; Kay Kendall Leukemia Fund, United Kingdom |
2006 Veteran's Administration; Netherlands Cancer Foundation (Stichting Koningin Wilhelmina Fonds); National Foundation - March of Dimes; United States-Israel Binational Science Foundation; North Carolina Board of Science and Technology; Kay Kendall Leukemia Fund, United Kingdom |
2008 Veteran's Administration; Netherlands Cancer Foundation (Stichting Koningin Wilhelmina Fonds); National Foundation - March of Dimes; United States-Israel Binational Science Foundation; North Carolina Board of Science and Technology; Kay Kendall Leukemia Fund, United Kingdom |
2009 Veteran's Administration; Netherlands Cancer Foundation (Stichting Koningin Wilhelmina Fonds); National Foundation - March of Dimes; United States-Israel Binational Science Foundation; North Carolina Board of Science and Technology; Kay Kendall Leukemia Fund, United Kingdom |
LISTED IN:: |
Who's Who in Science and Engineering,
Who's Who in the Midwest,
Who's Who in Medicine and Health Care,
American Men and Women of Science,
Who's Who in the World
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PATENTS: |
01/31/2005 US Patent Application # 20050169870
Methods of Modulating CD200
DNAX Research Institute, Palo Alto, CA
(Role: Co-Inventor with M. Rosenblum and E. Olasz)
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WORKSHOP REPORT: |
1975 The germ-free state: Transplantation aspects. Transplantation Proceedings 7(S1): 907 909 |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. McFadden GK, Truitt RL, Shechmeister IL. Ultrastructural examination of phytohemagglutinin stimulated lymphocytes infected with vesicular stomatitis virus. Arch Gesamte Virusforsch. 1973;41(3):229-37. |
2. Truitt RL, Schechmeister IL. The replication of bovine viral diarrhea-mucosal disease virus in bovine leukocytes in vitro. Arch Gesamte Virusforsch. 1973;42(1):78-87. |
3. Pollard M, Truitt RL. Allogeneic bone marrow chimerism in germfree mice. 1. Prevention of spontaneous leukemia in AKR mice. Proc Soc Exp Biol Med. 1973 Nov;144(2):659-65. |
4. Pollard M, Truitt RL. Allogeneic bone marrow chimerism in germ-free mice. II. Prevention of reticulum cell sarcomas in SJL-J mice. Proc Soc Exp Biol Med. 1974 Feb;145(2):488-92. |
5. Truitt RL, Pollard M, Srivastava KK. Allogeneic bone marrow chimerism in germfree mice. 3. Therapy of leukemic AKR mice. Proc Soc Exp Biol Med. 1974 May;146(1):153-8. |
6. Rose WC, Rimm AA, Saltzstein EC, Truitt RL, Bortin MM. Low-dose chemotherapy as a prelude to intensive treatment of spontaneous leukemia-lymphoma in AKR mice. J Natl Cancer Inst. 1975 Jul;55(1):219-21. |
7. Bortin MM, Rose WC, Truitt RL, Rimm AA, Saltzstein EC, Rodey GE. Graft versus leukemia. VI. Adoptive immunotherapy in combination with chemoradiotherapy for spontaneous leukemia-lymphoma in AKR mice. J Natl Cancer Inst. 1975 Nov;55(5):1227-9. |
8. Truitt RL, Pollard M. Allogeneic bone marrow chimerism in germ-free mice. IV. Therapy of "Hodgkin's-like" reticulum cell sarcoma in SJL mice. Transplantation. 1976 Jan;21(1):12-6. |
9. Rose WC, Rodey GE, Rimm AA, Truitt RL, Bortin MM. Mitigation of graft-versus-host disease in mice by treatment of donors with bacterial endotoxin. Exp Hematol. 1976 Mar;4(2):90-6. |
10. Bortin MM, Rimm AA, Rose WC, Truitt RL, Saltzstein EC. Transplantation of hematopoietic and lymphoid cells in mice. Transplantation. 1976 Apr;21(4):331-6. |
11. Pollard M, Truitt RL, Ashman RB. Mouse leukemia and solid tumors treated with bone marrow grafting. Transplant Proc. 1976 Dec;8(4):565-7. |
12. Bortin MM, Truitt RL, Rose WC, Rimm AA, Saltzstein EC. Adoptive immunotherapy of spontaneous leukemia-lymphoma in AKR mice. Adv Exp Med Biol. 1976;73 Pt B:331-9. |
13. Truitt RL, Rimm AA, Saltzstein EC, Rose WC, Bortin MM. Graft-versus-leukemia for AKR spontaneous leukemia-lymphoma. Transplant Proc. 1976 Dec;8(4):569-74. |
14. Bortin-M, Truitt RL. AKR T-cell acute lymphoblastic leukemia: a model for human T-cell leukemia. Biomedicine. 1977 Oct;26(5):309-11. |
15. Truitt RL, Rose WC, Rimm AA, Bortin MM. Graft versus leukemia. VIII. Selective reduction in antihost reactivity without loss of antileukemic reactivity by treatment of donor mice with lipopolysaccharide. Exp Hematol. 1978 May;6(5):488-98. |
16. Saltzstein EC, Rose WC, Truitt RL, Rimm AA, Bortin MM, Patillo RA. Growth of human tumors in lethally irradiated mice reconstituted with syngeneic fetal liver cells. Cancer. 1977 Feb;39(2):581-6. |
17. Bortin MM, Truitt RL, Rimm AA, Bach FH. Graft-versus-leukaemia reactivity induced by alloimmunisation without augmentation of graft-versus-host reactivity. Nature. 1979 Oct 11;281(5731):490-1. |
18. Truitt RL, Bortin MM, Rimm AA. Alloimmunization: induction of antileukemic reactivity without modification of anti-host reactivity in H-2-compatible mice. Transplant Proc. 1980 Mar;12(1):143-6. |
19. Bortin MM, Truitt RL, Shih CY, Rimm AA. Graft-versus-leukemia: allosensitization of MHC compatible donors induces antileukemic reactivity without amplification of antihost reactivity. Haematol Blood Transfus. 1980;25:31-9. |
20. Truitt RL, Shih CY, Rimm AA, Tempelis LD, Bortin MM. Alloimmunization and adoptive immunotherapy of leukemia. Transplant Proc. 1981 Dec;13(4):1910-4. |
21. Shih CY, Truitt RL, Andreani M, Bortin MM. Growth of AKR T cell leukemia lymphoblasts in medium containing interleukin 2 (IL-2). In Vitro. 1983 Oct;19(10):759-66. |
22. Bortin MM, Truitt RL, Shih CY, Tempelis LD, LeFever AV, Rimm AA. Alloimmunization for induction of graft-versus-leukemia reactivity in H-2-compatible donors: critical role for incompatibility of donor and alloimmunizing strains at non-H-2 loci. Transplant Proc. 1983 Dec;15(4):2114-7. |
23. Truitt RL, Shih CY, Lefever AV, Tempelis LD, Andreani M, Bortin MM. Characterization of alloimmunization-induced T lymphocytes reactive against AKR leukemia in vitro and correlation with graft-vs-leukemia activity in vivo. J Immunol. 1983 Oct;131(4):2050-8. |
24. LeFever AV, Truitt RL, Shih CC, Liepins A, Bortin MM. Migration patterns and functional activity of cloned cytotoxic T lymphocytes in syngeneic and allogeneic mice. Transplantation. 1984 Apr;37(4):410-7. |
25. Truitt RL, Shih CC. Isolation of suppressor-like T cells from bacteria-free allogeneic bone marrow chimeras. Prog Clin Biol Res. 1985;181:451-4. |
26. LeFever AV, Truitt RL, Shih CC. Reactivity of in-vitro-expanded alloimmune cytotoxic T lymphocytes and Qa-1-specific cytotoxic T lymphocytes against AKR leukemia in vivo. Transplantation. 1985 Nov;40(5):531-7. |
27. Truitt RL, Shih CC, LeFever AV. Manipulation of graft-versus-host disease for a graft-versus-leukemia effect after allogeneic bone marrow transplantation in AKR mice with spontaneous leukemia/lymphoma. Transplantation. 1986 Mar;41(3):301-10. |
28. LeFever AV, Truitt RL. Kinetic analysis of cloned cytotoxic T lymphocyte reactivity against normal and leukaemic target cells. J Immunogenet. 1986;13(2-3):275-85. |
29. LeFever AV, Truitt RL. Kinetic analysis of Qa-1-specific cloned cytotoxic T lymphocytes: lytic parameters and evaluation of cellular inhibition. Scand J Immunol. 1987 Jun;25(6):541-53. |
30. Shih CC, Truitt RL. A class II antigen-specific T cell clone can suppress graft-versus-host reactivity in murine allogeneic bone marrow chimeras. Transplant Proc. 1987 Feb;19(1 Pt 3):2664-7. |
31. Shih CC, Truitt RL. Downregulation of L3T4+ cytotoxic T lymphocytes by interleukin-2. Science. 1987 Oct 16;238(4825):344-7. |
32. Truitt RL, Ash RC. Manipulation of T-cell content in transplanted human bone marrow: effect on GVH and GVL reactions. Prog Clin Biol Res. 1987;244:409-21. |
33. LeFever AV, Truitt RL. Migration of cytotoxic effector cells. Prog Clin Biol Res. 1987;244:313-24. |
34. Shih CC, Truitt RL. Prophylaxis of graft-vs-host disease by adoptive transfer of a class II antigen-specific murine T-cell clone. Prog Clin Biol Res. 1987;244:439-47. |
35. Bunin NJ, Casper JT, Chitambar C, Hunter J, Truitt R, Menitove J, Camitta BM, Ash R. Partially matched bone marrow transplantation in patients with myelodysplastic syndromes. J Clin Oncol. 1988 Dec;6(12):1851-5. |
36. Liepins A, LeFever A, Truitt RL. Serotonin modulated Ca++ dependent K+ channels in alloimmune effector cell lytic function. Immunopharmacol Immunotoxicol. 1989;11(2-3):165-78. |
37. Drobyski W, Thibodeau S, Truitt RL, Baxter-Lowe LA, Gorski J, Jenkins R, Gottschall J, Ash RC. Third-party-mediated graft rejection and graft-versus-host disease after T-cell-depleted bone marrow transplantation, as demonstrated by hypervariable DNA probes and HLA-DR polymorphism. Blood. 1989 Nov 01;74(6):2285-94. |
38. Marmont AM, Gale RP, Butturini A, Goldman JM, Martelli MF, Prentice HG, Slavin S, Storb R, Truitt RL, Van Bekkum DW. T-cell depletion in allogeneic bone marrow transplantation: progress and problems. Haematologica. 1989;74(3):235-48. |
39. LeFever A, Liepins A, Truitt R. Role of K+ ion channels in lymphokine-activated killer (LAK) cell lytic function. Immunopharmacol Immunotoxicol. 1989;11(4):571-82. |
40. Horowitz MM, Gale RP, Sondel PM, Goldman JM, Kersey J, Kolb HJ, Rimm AA, Ringdén O, Rozman C, Speck B. Graft-versus-leukemia reactions after bone marrow transplantation. Blood. 1990 Feb 01;75(3):555-62. |
41. Ash RC, Casper JT, Chitambar CR, Hansen R, Bunin N, Truitt RL, Lawton C, Murray K, Hunter J, Baxter-Lowe LA. Successful allogeneic transplantation of T-cell-depleted bone marrow from closely HLA-matched unrelated donors. N Engl J Med. 1990 Feb 22;322(8):485-94. |
42. Drobyski WR, Piaskowski V, Ash RC, Casper JT, Truitt RL. Preservation of lymphokine-activated killer activity following T cell depletion of human bone marrow. Transplantation. 1990 Oct;50(4):625-32. |
43. LeFever AV, Piaskowski VD, Casper JT, Truitt RL. Kinetic analysis of human IL-2 activated cytotoxic cells. Immunopharmacol Immunotoxicol. 1991;13(1-2):147-68. |
44. Truitt RL, Atasoylu AA. Impact of pretransplant conditioning and donor T cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity, and tolerance after bone marrow transplantation. Blood. 1991 Jun 01;77(11):2515-23. |
45. Truitt RL, Atasoylu AA. Contribution of CD4+ and CD8+ T cells to graft-versus-host disease and graft-versus-leukemia reactivity after transplantation of MHC-compatible bone marrow. Bone Marrow Transplant. 1991 Jul;8(1):51-8. |
46. Drobyski WR, LeFever AV, Truitt RL. Regulation of lymphokine-activated killer activity in T-replete and T-cell-depleted human bone marrow by interleukin 4. Exp Hematol. 1991 Oct;19(9):950-7. |
47. Johnson BD, Truitt RL. A decrease in graft-vs.-host disease without loss of graft-vs.-leukemia reactivity after MHC-matched bone marrow transplantation by selective depletion of donor NK cells in vivo. Transplantation. 1992 Jul;54(1):104-12. |
48. Truitt RL, Piaskowski V, Kirchner P, McOlash L, Camitta BM, Casper JT. Immunological evaluation of pediatric cancer patients receiving recombinant interleukin-2 in a phase I trial. J Immunother (1991). 1992 May;11(4):274-85. |
49. Drobyski WR, Baxter-Lowe LA, Truitt RL. Detection of residual leukemia by the polymerase chain reaction and sequence-specific oligonucleotide probe hybridization after allogeneic bone marrow transplantation for AKR leukemia: a murine model for minimal residual disease. Blood. 1993 Jan 15;81(2):551-9. |
50. Johnson BD, Drobyski WR, Truitt RL. Delayed infusion of normal donor cells after MHC-matched bone marrow transplantation provides an antileukemia reaction without graft-versus-host disease. Bone Marrow Transplant. 1993 Apr;11(4):329-36. |
51. Johnson BD, Truitt RL. Delayed infusion of immunocompetent donor cells after bone marrow transplantation breaks graft-host tolerance allows for persistent antileukemic reactivity without severe graft-versus-host disease. Blood. 1995 Jun 01;85(11):3302-12. |
52. Johnson BD, McCabe C, Hanke CA, Truitt RL. Use of anti-CD3 epsilon F(ab')2 fragments in vivo to modulate graft-versus-host disease without loss of graft-versus-leukemia reactivity after MHC-matched bone marrow transplantation. J Immunol. 1995 May 15;154(10):5542-54. |
53. Flomenberg P, Piaskowski V, Truitt RL, Casper JT. Characterization of human proliferative T cell responses to adenovirus. J Infect Dis. 1995 May;171(5):1090-6. |
54. Casper J, Camitta B, Truitt R, Baxter-Lowe LA, Bunin N, Lawton C, Murray K, Hunter J, Pietryga D, Garbrecht F. Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia. Blood. 1995 May 01;85(9):2354-63. |
55. Ritch PS, Keever C, Schiller J, Rivkin S, Witt PL, Grossberg SE, Truitt RL, Burris H, von Hoff DD, Vaickus L. Phase IA/IB evaluation of mammalian cell-derived glycosylated recombinant human interleukin (SIGOSIX) before and after cytotoxic chemotherapy. Ann N Y Acad Sci. 1995 Jul 21;762:359-60. |
56. D'Cunha J, Knight E Jr, Haas AL, Truitt RL, Borden EC. Immunoregulatory properties of ISG15, an interferon-induced cytokine. Proc Natl Acad Sci U S A. 1996 Jan 09;93(1):211-5. PMCID: PMC40208 |
57. Keever-Taylor CA, Witt PL, Truitt RL, Ramanujam S, Borden EC, Ritch PS. Hematologic and immunologic evaluation of recombinant human interleukin-6 in patients with advanced malignant disease: evidence for monocyte activation. J Immunother Emphasis Tumor Immunol. 1996 May;19(3):231-43. |
58. Margolis D, Camitta B, Pietryga D, Keever-Taylor C, Baxter-Lowe LA, Pierce K, Kupst MJ, French J 3rd, Truitt R, Lawton C, Murray K, Garbrecht F, Flomenberg N, Casper J. Unrelated donor bone marrow transplantation to treat severe aplastic anaemia in children and young adults. Br J Haematol. 1996 Jul;94(1):65-72. |
59. Johnson BD, Hanke CA, Truitt RL. The graft-versus-leukemia effect of post-transplant donor leukocyte infusion. Leuk Lymphoma. 1996 Sep;23(1-2):1-9. |
60. Flomenberg P, Piaskowski V, Truitt RL, Casper JT. Human adenovirus-specific CD8+ T-cell responses are not inhibited by E3-19K in the presence of gamma interferon. J Virol. 1996 Sep;70(9):6314-22. PMCID: PMC190657 |
61. Truitt RL, Hanke C, Radke J, Mueller R, Barbieri JT. Glycosphingolipids as novel targets for T-cell suppression by the B subunit of recombinant heat-labile enterotoxin. Infect Immun. 1998 Apr;66(4):1299-308. PMCID: PMC108053 |
62. Johnson BD, Hanke CA, Becker EE, Truitt RL. Sca1(+)/Mac1(+) nitric oxide-producing cells in the spleens of recipients early following bone marrow transplant suppress T cell responses in vitro. Cell Immunol. 1998 Nov 01;189(2):149-59. |
63. Johnson BD, Becker EE, Truitt RL. Graft-vs.-host and graft-vs.-leukemia reactions after delayed infusions of donor T-subsets. Biol Blood Marrow Transplant. 1999;5(3):123-32. |
64. Truitt RL, Johnson BD, Hanke C, Talib S, Hearst JE. Photochemical treatment with S-59 psoralen and ultraviolet A light to control the fate of naive or primed T lymphocytes in vivo after allogeneic bone marrow transplantation. J Immunol. 1999 Nov 01;163(9):5145-56. |
65. Johnson BD, Becker EE, LaBelle JL, Truitt RL. Role of immunoregulatory donor T cells in suppression of graft-versus-host disease following donor leukocyte infusion therapy. J Immunol. 1999 Dec 15;163(12):6479-87. |
66. Johnson BD, Dagher N, Stankowski WC, Hanke CA, Truitt RL. Donor natural killer (NK1.1+) cells do not play a role in the suppression of GVHD or in the mediation of GVL reactions after DLI. Biol Blood Marrow Transplant. 2001;7(11):589-95. |
67. LaBelle JL, Hanke CA, Blazar BR, Truitt RL. Negative effect of CTLA-4 on induction of T-cell immunity in vivo to B7-1+, but not B7-2+, murine myelogenous leukemia. Blood. 2002 Mar 15;99(6):2146-53. |
68. LaBelle JL, Truitt RL. Characterization of a murine NKT cell tumor previously described as an acute myelogenous leukemia. Leuk Lymphoma. 2002 Aug;43(8):1637-44. |
69. Johnson BD, Konkol MC, Truitt RL. CD25+ immunoregulatory T-cells of donor origin suppress alloreactivity after BMT. Biol Blood Marrow Transplant. 2002;8(10):525-35. |
70. Browning MB, Woodliff JE, Konkol MC, Pati NT, Ghosh S, Truitt RL, Johnson BD. The T cell activation marker CD150 can be used to identify alloantigen-activated CD4(+)25+ regulatory T cells. Cell Immunol. 2004 Feb;227(2):129-39. |
71. Rosenblum MD, Olasz E, Woodliff JE, Johnson BD, Konkol MC, Gerber KA, Orentas RJ, Sandford G, Truitt RL. CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance. Blood. 2004 Apr 01;103(7):2691-8. |
72. Rosenblum MD, Olasz EB, Yancey KB, Woodliff JE, Lazarova Z, Gerber KA, Truitt RL. Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance? J Invest Dermatol. 2004 Nov;123(5):880-7. |
73. Xia G, Kovochich M, Truitt RL, Johnson BD. Tracking ex vivo-expanded CD4+CD25+ and CD8+CD25+ regulatory T cells after infusion to prevent donor lymphocyte infusion-induced lethal acute graft-versus-host disease. Biol Blood Marrow Transplant. 2004 Nov;10(11):748-60. |
74. Rosenblum MD, Woodliff JE, Madsen NA, McOlash LJ, Keller MR, Truitt RL. Characterization of CD 200-receptor expression in the murine epidermis. J Invest Dermatol. 2005 Dec;125(6):1130-8. |
75. Xia G, Truitt RL, Johnson BD. Graft-versus-leukemia and graft-versus-host reactions after donor lymphocyte infusion are initiated by host-type antigen-presenting cells and regulated by regulatory T cells in early and long-term chimeras. Biol Blood Marrow Transplant. 2006 Apr;12(4):397-407. |
76. Keever-Taylor CA, Browning MB, Johnson BD, Truitt RL, Bredeson CN, Behn B, Tsao A. Rapamycin enriches for CD4(+) CD25(+) CD27(+) Foxp3(+) regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with multiple sclerosis. Cytotherapy. 2007;9(2):144-57. |
Books, Chapters, and Reviews |
1. Bortin MM, Truitt RL, Rose WC, Rimm AA, Saltzstein EC. Adoptive immunotherapy of spontaneous leukemia-lymphoma in AKR mice. In: H Friedman, MR Escobar, and SM Reichard, eds. The Reticuloendothelial System in Health and Disease: Immunologic and pathologic aspects. Vol. 73B. New York: Plenum Press;1976:331-339. |
2. LeFeber WP, Truitt RL, Rose WC, Bortin MM. Graft versus leukemia. VII. Donor selection for adoptive immunotherapy in mice. In: SJ Baum, GD Ledney eds. New York: Springer-Verlag;1977:239-246. |
3. Truitt RL. Use of decontamination and a protected environment to prevent secondary disease following adoptive immunotherapy of acute leukemia in mice. In: SJ Baum, GD Ledney eds. Experimental Hematology Today. New York: Springer-Verlag;1978:195-201. |
4. Bortin MM, Truitt RL, Rimm AA. Nonspecific adoptive immunotherapy of T cell acute leukemia in man. In: H Waters ed. The Handbook of Cancer Immunology: Immunotherapy. Vol.5. New York: Garland STPM Press;1978:403-429. |
5. Truitt RL, Bortin MM, Rimm AA. Successful adoptive immunotherapy of AKR spontaneous T cell leukemia following antibiotic decontamination and protective isolation. In: T Fliedner, H Heit, D Niethammer, H Pfieger, eds. Clinical and Experimental Gnotobiotics. Stuttgart: Gustav Fischer Verlag;1979: 215-220. |
6. Bortin MM, Truitt RL, Shih CC-Y, Rimm AA. Graft-versus-leukemia: Allosensitization of MHC compatible donors induces antileukemic reactivity without amplification of antihost reactivity. In: S Thierfelder, H Rodt, HJ Kolb, eds. Immunobiology of Bone Marrow Transplantation. New York: Springer-Verlag;1980:31-39. |
7. MM Bortin, RT Truitt, ed. Alien histocompatibility antigens in cancer. New York: Grune and Stratton;1980. |
8. RL Truitt, RP Gale, MM Bortin, eds. Cellular Immunotherapy of Cancer. New York: Alan R. Liss;1987. |
9. Truitt RL, Johnson BD. Principles of graft-vs.-leukemia reactivity. Biol Blood Marrow Transplant. 1995 Dec;1(2):61-8. |
10. Bortin MM, Truitt RL, Shih CC-Y, Rimm AA. Graft versus leukemia. X. Induction of reactivity against murine leukemia in MHC compatible donors. In: JP OKunewick, RF Meredith, eds. Graft-vs-Leukemia in Man and Animal Models. Boca Raton, FL: CRC Press;1981:139-156. |
11. Fefer A, Truitt RL, Sullivan KM. Adoptive Cellular Therapy: Graft-vs-Tumor Responses after Bone Marrow Transplantation. In: VT DeVita, S Hellman and SA Rosenberg, eds. Biologic Therapy of Cancer: Principles and Practice. Philadelphia, PA: J.B. Lippincott Co.; 1991:237-246. |
12. Horowitz MM, Truitt RL. Graft-versus-leukemia effects of bone marrow transplantation. In: K Atkinson, ed. Clinical Bone Marrow Transplantation. Cambridge UK: Cambridge University Press;1994:704-14. |
13. Truitt RL, Johnson BD. Graft-versus-host disease and the graft-versus-leukemia effect: lessons from allogeneic bone marrow transplantation. In: T Spitzer, A Mazumder, eds. Immunotherapy and Bone Marrow Transplantation. Armonk, NY: Futura Publishing, Co.;1995:1-33. |
14. Truitt RL, Keever C, Borden EC. Role of IL-4, IL-6, and IL-12 in cancer therapy. In: VT DeVita, S Hellman, SA Rosenberg, eds. Biologic Therapy of Cancer, Second Edition. Philadelphia: JB Lippincott Co.;1995:279-293. |
15. Horowitz MM, Truitt RL. Graft-versus-leukemia effects of bone marrow transplantation. In: K Atkinson, ed. Clinical Bone Marrow and Blood Stem Cell Transplantation, Second Edition. Cambridge UK: Cambridge University Press;1999:1327-1338. |
16. Truitt RL, Komgold R, Johnson BD, Townsend R, Blazar BR. Experimental animal models in the study of GVL reactions. In: J Barrett, Y-Z Jiang, eds. Allogeneic Immunotherapy for Malignant Diseases. New York: Marcel Dekker;2000:39-74. |
17. Bredeson C, Horowitz MM, Truitt RL. Graft-versus-leukemia effects of bone marrow transplantation. In: K Atkinson, R Chaplin, J ritz, WE Fibbe, P Lungman, MK Brenner, eds. Clinical Bone Marrow Transplantation, Third Edition. Cambridge UK: Cambridge University Press;2004:291-310. |
18. Bortin MM, Truitt RT, eds. Alien histocompatibility antigens in cancer, Volume II. New York: Grune and Stratton;1982. |
19. Truitt RL. The Mortimer M. Bortin Lecture: to destroy by the reaction of immunity: the search for separation of graft-versus-leukemia and graft-versus-host. Biol Blood Marrow Transplant. 2004 Aug;10(8):505-23. |
20. Rosenblum MD, Yancey KB, Olasz EB, Truitt RL. CD200, a "no danger" signal for hair follicles. J Dermatol Sci. 2006 Mar;41(3):165-74. |
Abstracts |
1. Pollard M, Truitt RL. Applications of germfree technology to experimental problems of clinical significance. Proc First Intersect Cong Int Assoc Microbiol Sci. 1975; 3:250-259. |
