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CURRICULUM VITAE

Rowena C. Punzalan MD
Associate Professor
Department of Pediatrics
Division of Hematology and Oncology - Pediatrics

OFFICE ADDRESS:
MACC Fund Research Center
8701 Watertown Plank Rd
Milwaukee, WI 53226

EDUCATION:
06/1984 - 04/1988 B.S., University of the Philippines, Manila, Philippines
06/1986 - 05/1991 M.D., University of the Philippines College of Medicine, Manila, Philippines

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/1993 - 06/1996 Resident, Pediatrics, Medical College of Wisconsin Affiliated Hospitals, Milwaukee, WI
07/1996 - 12/1999 Fellowship, Pediatric Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
09/2003 - 09/2004 Fellowship, Transfusion Medicine and Blood Banking, Blood Center of Wisconsin and Medical College of Wisconsin, Milwaukee, WI

FACULTY APPOINTMENTS:
10/2005 - 06/2011 Assistant Clinical Professor, Department of Pediatrics, Section of Hematology/Oncology/Bone Marrow Transplant, Medical College of Wisconsin, Milwaukee, WI
10/2005 - Present Assistant Clinical Professor, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI
10/2005 - 03/2011 Associate Medical Director, Blood Center of Wisconsin, Milwaukee, WI
04/2011 - Present Medical Director, Blood Center of Wisconsin, Milwaukee, WI
07/2011 - 06/2013 Assistant Professor, Department of Pediatrics, Section of Hematology/Oncology Bone Marrow Transplant, Medical College of Wisconsin, Milwaukee, WI
07/2013 - Present Associate Professor, Department of Pediatrics, Section of Hematology/Oncology/Bone Marrow Transplant, Medical College of Wisconsin, Milwaukee, WI

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
09/2010 - 04/2013 Associate Director, Transfusion Medicine and Blood Banking Fellowship, Medical College of Wisconsin and Blood Center of Wisconsin, Milwaukee, WI
04/2013 - Present Program Director, Transfusion Medicine and Blood Banking Fellowship, Medical College of Wisconsin and Blood Center of Wisconsin, Milwaukee, WI

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
10/2005 - Present Medical Director, Transfusion Service, Children's Hospital of Wisconsin, 9000 W. Wisconsin Ave., Wauwatosa, WI 53226
10/2005 - 12/2012 Associate Medical Director, Blood Center of Wisconsin, Milwaukee, WI
01/2013 - Present Medical Director, Versiti Blood Center of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
10/2005 - Present Children's Hospital of Wisconsin, 9000 W. Wisconsin Ave., Wauwatosa, WI 53226
10/2005 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226
11/2005 - Present Aurora St. Luke's Medical Center (consulting staff, Pathology), 2900 W Oklahoma Ave, Milwaukee, WI 53215
11/2005 - Present Aurora Sinai Medical Center (consulting staff, Pathology), 945 North 12th Street. Milwaukee, WI 53233
11/2005 - Present Aurora West Allis Medical Center (consulting staff, Pathology), 8901 W. Lincoln Ave., West Allis, WI 53227
07/2007 - Present Aurora Medical Center Kenosha (consulting staff, Pathology), 10400 75th St, Kenosha, WI 53142
07/2007 - Present Aurora Memorial Hospital of Burlington (consulting staff, Pathology), 252 McHenry Street Burlington, WI 53105
07/2007 - Present Aurora Lakeland Medical Center (consulting staff, Pathology), W3985 County Road NN, Elkhorn, WI 53121

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Pediatrics
08/2002
12/2010
American Board of Pediatrics –Hematology/Oncology
11/2004
12/2022
American Board of Pathology – Trans-Fusion Medicine/Blood Banking
09/2006
12/2026
   
Licensure
Number Issue DateExpiration
Wisconsin License
36081-20
10/2007
10/31/2021
    

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
01/2006 - Present AABB (Blood Bank)
04/2006 - Present American Society of Hematology
2007 - Present Hemophilia and Thrombosis Research Society
2011 - Present Inspector for the College of American Pathologists

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
2006 - Present American Journal of Hematology
2014 - Present New England Journal of Medicine
2014 - Present British Journal of Hematology
2015 - Present Transfusion
2019 Pediatric Blood and Cancer
2019 Journal of Pediatric Intensive Care
2019 Journal of Physical Medicine and Rehabilitation

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2013 - Present Member, AABB Fellowship Directors Subsection, American Association of Blood Banks

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
A Randomized, Open-Label, Active Controlled, Safety and Descriptive Efficacy Study of Apixaban in Pediatric Subjects Requiring Anticoagulation for the Treatment of a Venous Thromboembolic Event
Source:
Pfizer
Role & Effort:
Local principal investigator
Dates:
05/2015 - Present
Direct Funds:
$385,000 ((so far, since start))
  
Title:
A Phase 3, Open-Label, Randomized, Multi-Center, Controlled Trial To Evaluate The Pharmacokinetics and Pharmacodynamics of Edoxaban and To Compare the Efficacy and Safety of Edoxaban with Standard of Care Anticoagulant Therapy in Pediatric Subjects from Birth to Less Than 18 Years of Age with Confirmed Venous Thromboembolism (VTE)
Source:
Daiichi Sankyo
Role & Effort:
Local co-investigator
Dates:
11/2016 - Present
  
Title:
ALXN1210-PNH-304, A Phase 3, Open-Label Study of ALXN1210 in Children and Adolescents with Paroxysmal Nocturnal Hemoglobinuria (PNH)
Source:
Alexion
Role & Effort:
Local principal investigator
Dates:
10/2018 - Present
Direct Funds:
$82,122 (($65,236.26 per patient))
  
Title:
t-PA Prophylaxis to Reduce Central Venous Catheter Associated Infection and Thrombosis
Source:
NIH
Role & Effort:
local Co-investigator
Dates:
12/2018 - Present
  
Prior
Peer Review
Title:
Determination of the Optimal Prophylactic Platelet Dose to Prevent Bleeding
Source:
NHLBI
Role & Effort:
Principal Investigator at CHW
Dates:
10/2005 - 12/2007
  
Title:
High Dose Granulocyte Transfusions for the Treatment of Infection in Neutropenia
Source:
NHLBI
Role & Effort:
Local principal investigator
Dates:
05/2008 - 06/2011
  
Title:
Resolving Infection in Neutropenia with Granulocytes
Source:
NHLBI
Role & Effort:
Principal Investigator at CHW
Dates:
06/2008 - 2010
  
Title:
Duration of Therapy for Thrombosis in Children (Kids-DOTT)
Source:
NHLBI
Role & Effort:
Principal Investigator at CHW
Dates:
12/2011 - Present
  
Title:
Single-Dose Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Apixaban in Pediatric Subjects at Risk for a Venous or Arterial Thrombotic Disorder
Source:
Bristol-Myers Squibb
Role & Effort:
Local co-investigator
Dates:
04/2013 - 12/2019
  
Title:
Age of Blood in Children
Source:
NIH
Role & Effort:
Local co-investigator
Dates:
04/2014 - 01/2020
  
Title:
A Phase 1, Open-Label, Single-Dose, Non-Randomized Study to Evaluate Pharmacokinetics and Pharmacodynamics of Edoxaban in Pediatric Patients
Source:
Daiichi Sankyo
Role & Effort:
Local co-investigator
Dates:
01/2015 - 02/2020
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
International
RC Punzalan, Coagulation in infants and children, AABB annual meeting, New Orleans, LA, 10/2009
RC Punzalan, Extracorporeal photopheresis in children, AABB Annual Meeting, Philadelphia, PA, 10/2014
RC Punzalan, Thrombotic Disorders in Children, Pediatric Grand Rounds. St. Luke's Medical Center, Quezon City, Philippines, 07/2017 - Present
RC Punzalan, Recurrent Allergic Transfusion Reactions., AABB annual meeting, Virtual, 10/2020
 
National
RC Punzalan, Red Cell Genotyping Patients - The Clinician's Perspective, Academy of Clinical Laboratory Physicians and Scientists Annual Meeting, Milwaukee, WI, 05/31/2012
RC Punzalan, Transfusion Medicine, 2019 American Society of Pediatric Hematology Oncology Review Course, Irving, TX, 02/01/2019
 
Regional
RC Punzalan, Issues in Pediatric Transfusion Medicine, Wisconsin Association of Blood Banks Annual Meeting, Appleton, WI, 09/11/2008 - 09/12/2008
RC Punzalan, Transfusion Therapy in Sickle Cell Disease, Association of Clinical Laboratory Scientists - WI Spring Meeting, Pewaukee, WI, 04/07/2011
 
Local
RC Punzalan, Update on the Treatment of Hemophilia and von Willebrand Disease, Pharmacy Grand Rounds, Aurora St. Luke's Medical Center, Milwaukee WI, 05/2007
RC Punzalan, Selection of Blood Products: Overview and Special Needs, Aurora Clinical labs annual seminar, West Allis, WI, 10/2008 - Present
RC Punzalan, Blood Transfusion in Pediatric Hematology-Oncology, Association of Pediatric Hematology Oncology Nurses Wisconsin Chapter Meeting, Wauwatosa, WI, 04/2013
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
International
R.C. Punzalan, M.C. Du, J.P. Scott, P.S. Low, and C.A. Hillery. Role of hydration status in erythrocyte adhesion to thrombospondin. Oral presentation at the American Society of Hematology Annual Meeting, San Diego, CA, 1997.
 

COMMITTEE SERVICE:
Medical College of Wisconsin
10/2005 - 10/2008 Member, Scholarship oversight committee for Sheila Hanson, MD, Medical College of Wisconsin
05/2012 - 10/2012 Member, Scholarship Oversight Committee for Hemalatha Rangarajan Fellow, Medical College of Wisconsin
06/2012 - 12/2012 Faculty Reviewer, Critical Care Medicine Fellowship Program Internal Review Committee, Medical College of Wisconsin
 
Hospital
10/2007 - Present Chair, Blood Utilization Committee, Children's Hospital of Wisconsin
01/2008 - Present Chair, Anticoagulation Committee, Children's Hospital of Wisconsin
05/2009 - Present Member, Anticoagulation Committee, Children's Hospital of Wisconsin
2010 Alternate member, Institutional Review Board, Blood Center of Wisconsin
2011 - 2015 Member, Institutional Review Board, Blood Center of Wisconsin
10/2012 - Present Member, Committee on Prevention of Hospital-aquired conditions (thromboembolism), Children's Hospital of Wisconsin
 

MCW TEACHING ACTIVITIES:
Medical Student Education
11/2006 - Present M2 lectures; topic: Transfusion Medicine
2010 - 2012 Teaching attending at Morning Report (monthly), CHW
 
Graduate Student Education
06/2008 - Present Pediatric Surgery Physician Assistants lecture series; topic: Pediatric Transfusion Medicine
09/2010 - Present Pediatric Hematology Nurse Practitioners; topic: Evaluation of Immune Hemolysis
 
Resident and Fellow Education
07/2006 - 07/2009 Pathology resident lecture series; topic: Introduction to Transfusion Medicine
08/2006 - Present Transfusion Medicine fellow lecture series; topic: Hemoglobinopathies
08/2006 - Present Transfusion Medicine fellow lecture series; topic: Hematopoietic Growth Factors
08/2006 - Present Pediatric resident noon academic conference; topic: Pediatric Transfusion Medicine
07/2007 - Present Pediatric hematology/oncology fellow lecture series; topic: Pediatric Transfusion Medicine
07/2007 - Present Pediatric hematology/oncology fellow lecture series; topic: Immune Hemolytic Anemia
01/2008 - Present Hematology/Oncology/Transplant resident's lecture; Topic: Pediatric Transfusion Medicine
07/2009 - Present Pathology resident lecture series; topic: Adverse Events - Blood Transfusion
08/2009 - Present Transfusion Medicine fellow lecture series; topic: Issues in Pediatric Transfusion
07/2010 - 2011 Morning report with pediatric residents: case-based teaching
07/2010 - Present Pathology resident lecture series; topic: Evidence-based Indications for Transfusion
05/2011 - Present Pediatric resident board review series; topic: Thrombocytopenia in Infants and Children
2016 - 2017 Hematology/Oncology/Transplant resident's lecture, Topic: Bleeding and Thrombosis in Children
2016 - 2017 Hematology/Oncology/Transplant resident's lecture, Topic: Hemolytic anemia
 
Continuing Medical Education
08/2006 Neonatology Noon Conference; topic: Blood Banking
09/2007 Pediatric Surgery Grand Rounds; topic: Deep Venous Thrombosis in Children
05/2009 Neonatology Academic Conference; topic: Neonatal Transfusion Issues
10/2009 Pediatric Surgery/Emergency Medicine joint conference; topic: Transfusion Issues in the ED
10/2009 Pediatric Critical Care Lecture Series; topic: Use of rFVIIa and AT3 in the PICU
07/2011 Pediatric Emergency Medicine Grand Rounds; topic: Pediatric Thrombotic Disease
05/2012 Section of Allergy Grand Rounds; topic: Neutrophil Disorders
03/2014 Section of Pediatric Cardiology Research Conference: topic: Anticoagulation in Pediatric Cardiac Disease
05/2016 Section of Allergy Grand Rounds; topic: Neutrophil Disorders
06/2016 Section of Pediatric Hematology/Oncology/BMT Tumor Board; topic: Red Blood Cell transfusion updates
02/2018 Section of Adolescent Medicine Grand Rounds; topic: Overview of bleeding and thrombotic disorders in adolescents
07/2018 Section of Neonatology; topic: Cytomegalovirus infections and transfusion in neonates
 
Community/Lay Public
04/2009 CHW Oral Anticoagulation Symposium; topic: Warfarin Metabolism
04/2011 Drug-induced hemolytic anemia on-line education module
 

EXTRAMURAL TEACHING:
Continuing Medical Education
08/2006 - Present Specialist in Blood Banking lecture series; Blood Center of Wisconsin; topic: Hemoglobinopathies
2006 - 2013 Specialist in Blood Banking lecture series; Blood Center of Wisconsin; topic: Hematopoietic Growth Factors
08/2009 - Present Specialist in Blood Banking series; Blood Center of Wisconsin; topic: Issues in Pediatric Transfusion
2010 - 2012 Marquette University Acute Care Pediatric Nurse Practitioner program; topic: Pediatric Hematologic Emergencies
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Clinical/Research Fellows
10/2005 - 10/2008 Sheila Hanson MD, Oversight Committee Member, Medical College of Wisconsin
2009 Sweta Gupta, MD, Mentor, Medical College of Wisconsin
2009 Carmen Briones, MD, Mentor, Medical College of Wisconsin
2012 Chelsea Collins, MD, Mentor, Medical College of Wisconsin
2012 Hemalatha Rangarajan, MD, Mentor / Oversight Committee, Medical College of Wisconsin
2013 - 2015 Asfaw Asfawassen MD, Research Mentor / Oversight Committee, Medical College of Wisconsin
 
Residents
2010 Amanda Reiswig, Research project mentor, MCW
2020 - 2021 Maria Clarise Valencia MD, Research, Medical College of Wisconsin
2021 - Present Abinav Grover, MD, Research, Medical College of Wisconsin
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Graduate Students
Students Advised
01/2019 - 06/2020 Natalie Phillips MT, Comparison of Small Volume and Large Volume Transfusions of RBCs containing Adsol in Pediatric Patients Less than 6 Months Old Undergoing Cardiopulmonary Bypass Surgery, Blood Center of Wisconsin, - For this paper Ms. Phillips won the 2019 AABB Future Leader SBB Scholarship Award
2020 - 2021 Rachel Pietrzak MT, Versiti
 
Clinical/Research Fellows
2012 Kyle Annen, DO, Mentor, Medical College of Wisconsin and Blood Center of Wisconsin
2016 Waseem Anani MD, Academic, MCW Blood Banking/Transfusion Medicine
2017 Sarah Tehseen MBBS, Academic, MCW Blood Banking/Transfusion Medicine
 

PROGRAMMATIC DEVELOPMENTS:
Educational Programs
Fellow
2010 - Present Transfusion medicine and Blood banking curriculum for transfusion medicine and pediatric hematology/oncology/bone marrow transplant fellows
Resident
2016 - 2017 Pediatric Hematology curriculum for Pediatric Hematology/Oncology/Transplant residents
 
 
Clinical Programs
2010 - Present Children's Hospital of Wiscsonin Extracorporeal Photopheresis Program
Children's Wisconsin Program For Prevention Of Venous Thromboembolism
Children's Wisconsin Thrombosis Program
Children's Wisconsin Erythrocytapheresis Program
 
 

COMMUNITY SERVICE ACTIVITIES:
2015 - Present Philippine Center Free Clinic, Milwaukee WI (volunteer and fundraising board member)
2016 Philippine Center Free Clinic, Milwaukee WI (fundraising committee chair)
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. R.C. Punzalan, C.A. Hillery, R.R. Montgomery, J.P. Scott, and J.C. Gill. Low molecular weight heparin (enoxaparin) in thrombotic disease in children and adolescents. Journal of Pediatric Hematology Oncology 22(2):137-142, Mar-Apr 2000.
2. Greenbaum L.A., Kerlin B.A., Van Why S., Punzalan R.C., Trost B.A., Pan C.G., Scott J.P. Concurrent poststreptococcal glomerulonephritis and autoimmune hemolytic anemia. Pediatric Nephrology 18(12):1301-3, 2003.
3. N.J. Wandersee, R.C. Punzalan, M.P. Rettig, M.D. Kennedy, N.M. Pajewski, R.L. Sabina, J.P. Scott, P.S. Low, C.A. Hillery. Erythrocyte adhesion is modified by alterations in cellular tonicity and volume. British Journal of Haematology 131:366-377, 2005.
4. S.J. Hanson, R.C. Punzalan, N. Ghanayem, P.L. Havens. Prevalence of heparin-dependent platelet antibodies in children after cardiopulmonary bypass surgery. Pediatric Critical Care Medicine, 8(4):358, 2007.
5. S.J. Hanson, R.C. Punzalan, R.A. Greenup, H Liu, T.T. Sato, P.L. Havens. Incidence and Risk Factors for Venous Thromboembolism in Critically Ill Children after Trauma. Journal of Trauma, 68(1):52, 2010.
6. R.A. Neibler, R.C. Punzalan, M. Gamez, M.W. Lankiewicz. Activated Recombinant Factor VII for Refractory Bleeding During Extracorporeal Membrane Oxygenation. Pediatric Critical Care Medicine, 11(1):98, 2010.
7. S Gupta, CL Piefer, JT Fueger, ST Johnson, RC Punzalan. Trimethoprim-Induced Immune Hemolytic Anemia in a Pediatric Oncology Patient Presenting As an Acute Hemolytic Transfusion Reaction. Pediatric Blood and Cancer, 55:1201, 2010.
8. Rangarajan HG, Punzalan RC, Camitta BM, Talano JA. The use of novel Therakos™ Cellex® for extracorporeal photopheresis in treatment of graft-versus-host disease in paediatric patients. Br J Haematol. 2013 Nov;163(3):357-64.
9. Collins CL, Scott JP, Panepinto JA, Punzalan RC. Severe thrombocytopenia in a child secondary to passive platelet antibody transfer from a plasma transfusion. J Pediatr Hematol Oncol. 2013 Jul;35(5):e226-8. PMCID: PMC4508016
10. Franzblau EB, Punzalan RC, Friedman KD, Roy A, Bilen O, Flood VH. Use of purified fibrinogen concentrate for dysfibrinogenemia and importance of laboratory fibrinogen activity measurement. Pediatr Blood Cancer. 2013 Mar;60(3):500-2. PMCID: PMC4461026
11. Hanson SJ, Punzalan RC, Arca MJ, Simpson P, Christensen MA, Hanson SK, Yan K, Braun K, Havens PL. Effectiveness of clinical guidelines for deep vein thrombosis prophylaxis in reducing the incidence of venous thromboembolism in critically ill children after trauma. J Trauma Acute Care Surg. 2012 May;72(5):1292-7.
12. Schloemer NJ, Abu-Sultaneh S, Hanson SJ, Yan K, Hoffmann RG, Punzalan RC, Havens PL. Higher doses of low-molecular-weight heparin (enoxaparin) are needed to achieve target anti-Xa concentrations in critically ill children*. Pediatr Crit Care Med. 2014 Sep;15(7):e294-9.
13. SJ Hanson, RC Punzalan, NS Ghanayem, PL Havens. Incidence and risk factors for venous thromboembolism in critically ill children with cardiac disease. Pediatric Cardiology 33(1):103, 2012.
14. JP Scott, DJ Costigan , GM Hoffman, PM Simpson, M Dasgupta, RC Punzalan, RJ Berens, JS Tweddell, EAE Stuth. Increased recombinant activated factor VII use and need for surgical reexploration following a switch from aprotinin to epsilon-aminocaproic acid in infant cardial surgery. Journal of Clinical Anesthesia 26:2014-211, May 2014.
15. Niebler RA, Woods KJ, Murkowski K, Ghanayem NS, Hoffman G, Mitchell ME, Punzalan RC, Scott JP, Simpson P, Tweddell JS. A Pilot Study of Antithrombin Replacement Prior to Cardiopulmonary Bypass in Neonates. Artif Organs. 2016 Jan;40(1):80-5.
16. Punzalan RC, Gottschall JL. Use and Future Investigations of Recombinant and Plasma-Derived Coagulation and Anticoagulant Products in the Neonate. Transfus Med Rev. 2016 Oct;30(4):189-96.
17. Asfaw AB, Punzalan RC, Yan K, Hoffmann RG, Hanson SJ. Screening Guidelines for Venous Thromboembolism Risk in Hospitalized Children Have Low Sensitivity for Central Venous Catheter-Associated Thrombosis. Hosp Pediatr. 2017 Jan;7(1):39-45.
18. Landisch RM, Hanson SJ, Cassidy LD, Braun K, Punzalan RC, Gourlay DM. Evaluation of guidelines for injured children at high risk for venous thromboembolism: A prospective observational study. J Trauma Acute Care Surg. 2017 May;82(5):836-844.
19. Landisch RM, Hanson SJ, Cassidy LD, Braun K, Punzalan RC, Gourlay DM. Evaluation of guidelines for injured children at high risk for VTE: A prospective observational study. J Trauma Acute Care Surg. 2017 Mar 02.
20. Landisch RM, Hanson SJ, Punzalan RC, Braun K, Cassidy LD, Gourlay DM. Efficacy of surveillance ultrasound for venous thromboembolism diagnosis in critically ill children after trauma. J Pediatr Surg. 2018 Nov;53(11):2195-2201.
21. Onyeama SN, Hanson SJ, Dasgupta M, Baker K, Simpson PM, Punzalan RC. Central Venous Catheter-associated Venous Thromboembolism in Children With Hematologic Malignancy. J Pediatr Hematol Oncol. 2018 Nov;40(8):e519-e524.
22. Landisch RM, Hanson SJ, Punzalan RC, Braun K, Cassidy LD, Gourlay DM. Efficacy of surveillance ultrasound for venous thromboembolism diagnosis in critically ill children after trauma. J Pediatr Surg. 53(11):2195-2201, Nov 2018.
23. Anani W, Dobrozsi S, Punzalan RC. Identification of Peanut allergen in a transfused blood product causing transfusion associated anaphylaxis. Transfusion. 60(5):1108-1109, May 2020.
 
Books, Chapters, and Reviews
1. Punzalan, RC. Hemostatic Disorders. Pediatric Transfusion: A Physician's Handbook, 3rd edition, 2009.
2. Punzalan, R.C., Flood, V.H. Developmental Hemostasis. Textbook of Clinical Pediatrics, 2nd edition. Elzouki, A.Y., ed. Springer; in press.
3. Punzalan, RC, Flood, VH. Developmental Hemostasis. Textbook of Clinical Pediatrics, 2nd edition. Elzouki, AY ed. Springer, 2012.
4. Punzalan RC, Scott JP. Blood Component Therapy. Nelson's Essentials of Pediatrics. Behrman R and Kliegman R, Eds. In Press, 2014.
5. Punzalan RC, contributing editor. Pediatric Transfusion: A Physician's Handbook, 4th edition. Wong E and King K, eds. AABB, 2015.
6. Punzalan RC and Gottschall JL. Use and future investigations of recombinant and plasma-derived coagulation and anticoagulant products in the neonate. Transfusion Medicine Reviews 30 (2016) 189-196.
7. Wong ECC and Punzalan RC. Neonatal and Pediatric Transfusion Practice. In Technical Manual 19th edition. Fung MK, Eder AF, Spitalnik SL, Westhoff CM, eds. AABB, 2017
8. Wong ECC and Punzalan RC. Neonatal and Pediatric Transfusion Practice. In Technical Manual 20th edition. Fung MK, Eder AF, Spitalnik SL, Westhoff CM, Delaney M, eds. AABB, 2020.
9. Punzalan RC, contributing editor. Pediatric Transfusion: A Physician's Handbook, 5th edition. Wong E and Roseff S, eds. AABB, 2020.
10. Wong ECC, Punzalan RC. "Pediatric Thrombotic Disorders" in Biochemical Basis of Pediatric Disease, 5th Edition. Dietzen D, Bennett M, Wong ECC, Hammond S (eds), Elsevier, 2021(in preparation).
 
Abstracts
1. R.C. Punzalan, M.C. Du, J.P. Scott, P.S. Low, and C.A. Hillery. Role of hydration status in erythrocyte adhesion to thrombospondin. Blood 90(10, Suppl 1):604a, 1997.
2. R.C. Punzalan, B.A. Trost, H. Shen, J.P. Scott, A.G. Hudetz, and C.A.Hillery. Chondroitin sulfate-A limits cerebral ischemia induced by nitric oxide inhibition in sickle erythrocyte-infused rats. Blood 92(10, Suppl 1):329a, 1998.
3. R.C. Punzalan, S. Holzman, B.A. Trost, C. Paszty, N. Mohandas, and C.A. Hillery. Spontaneous stroke and erythrocyte adhesion in the transgenic knockout sickle cell mouse. Blood 94 (10 Suppl 1):304a, 1999.
4. M. Gamez, R.A. Neibler, M.W. Lankiewicz, R.C. Punzalan. Risk of thrombosis with recombinant factor VIIa during extracorporeal membrane oxygenation. Transfusion 46(9S):11a, Sept 2006.
5. Marchan MG, Leszczynski LA, Curnes JS, Rauter JJ, Punzalan RC, Johnson ST. Passive anti-E in a pediatric patient not detected by routine donor screening using anti-IgG solid screen II or gel test. Transfusion 47:160a, 2007.
6. TM Pugh, ST Johnson, LC Brenner, CL Piefer, MW Lankiewicz, RC Punzalan. Acute hemolytic transfusion reaction due to anti-Lea in a patient with sickle cell disease. Transfusion 47:150a, 2007.
7. S.J. Hanson, R.C. Punzalan, R.A. Greenup, H Liu, T.T. Sato, P.L. Havens. Incidence and Risk Factors for Venous Thromboembolism in Critically Ill Children after Trauma. Hemophilia and Thrombosis research Society annual meeting, April 2008.
8. C Piefer, RC Punzalan, KE Puca, N Leon, ST Johnson. Bactrim/Trimethoprim-Induced Immune Hemolytic Anemia in The Setting Of An Acute Hemolytic Transfusion Reaction. Transfusion 48:174a, 2008.
9. SJ Hanson, RC Punzalan, NS Ghanayem, PL Havens. Incidence and risk factors for venous thromboembolism in critically ill children with cardiac disease, oral presentation at the XXII Congress of the International Society on Thrombosis and Haemostasis, Boston, MA (07/2009)
10. SJ Hanson, RC Punzalan, NS Ghanayem, M Christensen, EM Kuhn, PL Havens. Incidence and risk factors for venous thromboembolism in critically ill children with cardiac disease, oral presentation at the American Academy of Pediatrics National Conference & Exhibition, San Francisco, CA (10/2010)
11. SJ Hanson, RC Punzalan, M Arca, P Simpson, M Christensen, PL Havens. Effectiveness of Clinical Guidelines for DVT Prophylaxis in Reducing the Incidence of Venous Thromboembolism in Critically Ill Children after Trauma. 40th Critical Care Congress, San Diego, CA, 1/15-1/19/2011.
12. RC Punzalan, JC Gill, RR Montgomery, SL Haberichter, KD Friedman. Reference Interval for Factor VIII to Von Willebrand Factor Antigen is Lower for Infants under 6 Months of Age Compared to Older Children and Adults. Accepted at the XXIII Congress of the International Society on Thrombosis and Haemostasis on July 23-28, 2011 in Kyoto, Japan.
13. Children's Hospital of Wisconsin: Blood Utilization Guidelines, Massive Transfusion Guidelines, Guidelines for VTE prophylaxis in Trauma, Guidelines for anticoagulation with warfarin, Guidelines for anticoagulation with heparin, Guidelines for anticoagulation with enoxaparin
14. C Collins, M Briggs, J Panepinto, JP Scott, RC Punzalan. Severe Thrombocytopenia in a Child Secondary to Passive Platelet Antibody Transfer from Plasma Transfusion. AABB Annual Meeting, San Diego, CA. 10/2011.
15. EB Franzblau, RC Punzalan, KD Friedman, VH Flood. Inter-Laboratory Variability in Measurement of Fibrinogen Following Purified Fibrinogen Concentrate for Dysfibrinogenemia. American Society of Pediatric Hematology Oncology Annual Meeting. New Orleans, LA. 5/2012.
16. NJ Schloemer, S Abu-Sultaneh, SJ Hanson, K Yan, RG Hoffmann, RC Punzalan, PL Havens. Higher Doses of Low Molecular Weight Heparin (LMWH)are Needed to Achieve Goal Anti-Xa Levels in Critically Ill Children. Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis Annual Meeting. Liverpool, UK. 6/2012.
17. M Mulberry, DA Margolis, RC Punzalan, M Kelly, M Browning. Autologous Stem Cell Collection for the Treatment of Malignant Disease in Pediatric Patients: The Use of the Power Hickman. 2013 American Society for Blood and Marrow Transplantation Tandem Meetings. Salt Lake City, UT. 2/2013.
18. HG Rangarajan, RC Punzalan, JA Talano. The Safety and Tolerability of the Novel Therakos Cellex Machine for Extracorporeal Photopheresis in the Treatment of GVHD in Children. 20123 American Society for Blood and Marrow Transplantation Tandem Meetings. Salt Lake City, UT. 2/2013.
19. HL Chang, A Ertl, J Enters, RC Punzalan, LD Cassidy, DM Gourlay. Massive Transfusion Protocol Improves Resuscitation in a Pediatric Level 1 Trauma Center. 2013 American Academy of Pediatrics (AAP National Conference and Exhibition. Orlando, FL 10/2013.
20. R Dora, S Graminski, S Heldke, S Brooks, M de Arruda Indig, RC Punzalan. In Vitro Explanation of Stored Pediatric Apheresis Platelet Aliquots AABB Annual Meeting. Denver, CO. 10/2013.
21. A Asfawossen, SH Hanson, K Yan, R Hoffmann, RC Punzalan. Sensitivity of Screening Guideline for Identification of Hospitalized Children at Risk for Venous Thromboembolism. Pediatric Critical Care Colloquium 2014, Huntington Beach, CA (9/2014).
22. R Landisch, SJ Hanson, RC Punzalan, K Braun, D Gourlay. Anticoagulation for venous thromboembolism: prophylaxis and treatment in children with severe traumatic brain injury. Thrombosis and Hemostasis Societies of North America 2016 meeting, Chicago, IL (4/2016).
23. JP Scott, RA Niebler, EAE Stuth, DW Benson, RK Woods, J S Tweddell, R Cole, ME Mitchell, RS Bercovitz, P Simpson, R Montgomery, A Mast, S Maroney, K Yan, RC Punzalan, DK Newman . Proactive Platelet and Cryoprecipitate Transfusion during Neonatal Cardiopulmonary Bypass Rapidly Normalizes Platelet Count, Fibrinogen, and Functional Rotational Thromboelastometry Parameters. Annual Meeting of the American Association for Thoracic Surgery, Baltimore, MD (5/2016).
24. WQ Anani, RC Punzalan. Peanut Allergen-Induced Anaphylactic Transfusion Reaction. AABB Annual Meeting, Orlando, FL (10/2016).
25. S Tehseen, RC Punzalan, R Udani, KD Friedman. Atypical Hemolytic Uremic Syndrome: Is complement pathway mutation analysis over-utilized? Experience of a large reference laboratory. AABB Annual Meeting, San Diego, CA (10/2017).
26. NA Phillips, R Berens, RC Punzalan. Comparison of Small Volume and Large Volume Transfusions of RBCs containing Adsol in Pediatric Patients Less than 6 Months Old Undergoing Cardiopulmonary Bypass Surgery. AABB Annual Meeting, San Antonio, TX (10/2019).
 
Database, Video, or Other Research/Clinical Contributions
1. Anticoagulation clinical database
2. Blood utilization database
3. Developed Guidelines at Children’s Hospital of Wisconsin: Blood Utilization Guidelines Massive Transfusion Guidelines Guidelines for Venous Thromboembolism prophylaxis in Trauma (co-developed) Guidelines for anticoagulation with warfarin Guidelines for anticoagulation with heparin Guidelines for anticoagulation with enoxaparin Guidelines for Systemic Thrombolysis (co-developed) Guidelines for anticoagulation with fondaparinux Guidelines for Venous Thrombosmebolism prophylaxis (co-developed)
 
Software, Software Modules
1. Blood product ordering and transfusion reaction modules for Sunrise Clinical Manager, CHW
2. Anticoagulation modules for Sunrise Clinical Manager, CHW
3. Blood product ordering and transfusion reaction modules for Epic, CHW
4. Anticoagulation modules for Epic, CHW