CURRICULUM VITAE
Sandra L. Pfister PhD
Sandra L. Pfister PhD
Professor
Department of Pharmacology and Toxicology
Department of Pharmacology and Toxicology
OFFICE ADDRESS: |
8701 Watertown Plank Road |
Milwaukee, WI 53226 |
EDUCATION: |
1974 - 1978 B.S., St. Mary's University, San Antonio, TX |
1978 - 1984 Ph.D., University of Texas Health Science Center (UTHSC), San Antonio, TX |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
1978 - 1984 Teaching Assistant, Pharmacology & Toxiocology, UTHSC, San Antonio, TX |
1984 Postdoctoral Fellow, Pharmacology & Toxiocology, UTHSC, San Antonio, TX |
1985 - 1988 Postdoctoral Fellow, Pharmacology, UT Southwestern Medical Center, Dallas, TX |
FACULTY APPOINTMENTS: |
1982 Adjunct Faculty, St. Mary's University, San Antonio, TX |
1988 - 1992 Instructor, Pharmacology, UT Southwestern Medical Center, Dallas, TX |
1992 - 1998 Assistant Professor, Pharmacology & Toxiocology, Medical College of Wisconsin, Milwaukee, WI |
1998 - 2018 Associate Professor, Pharmacology & Toxiocology, Medical College of Wisconsin, Milwaukee, WI |
2018 - Present Professor, Pharmacology & Toxicology, Medical College of Wisconsin |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
2012 - 2023 M2 Cardiovascular Unit Director Discovery Curriculum, MCW |
2017 - 2023 Course Director, Principles of Drug Action. Discovery Curriculum, MCW |
2022 - Present CV Block Director Phase 1. MCWfusion, MCW |
2022 - Present Medical Knowledge Discipline Expert,Pharmacology, MCWfusion, MCW |
2023 - Present Member, Advancement and Remediation Team (ART) MCWfusion, MCW |
AWARDS AND HONORS: |
1976 Delta Epsilon Sigma Honor Society |
1996 Finalist for the 1996 Council for High Blood Pressure Research Harry Goldblatt Award in Cardiovascular Research |
1996 Elected Fellow of the Council for High Blood Pressure Research |
1997 Recipient of the 1997 Council for High Blood Pressure Research Harry Goldblatt Award in Cardiovascular Research |
2008 - 2010 Outstanding Medical School Teacher, MCW |
2012 - 2015 Outstanding Medical School Teacher, MCW |
2016 - 2019 Outstanding Medical School Teacher, MCW |
2017 Society for Teaching Scholars, MCW |
2020 - 2023 Outstanding Medical School Teacher, MCW |
2022 Distinguished Service Award, MCW |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
1993 - Present American Heart Association Council on Basic Science Member (Member) |
1995 - Present American Society for Pharmacology & Experimental Therapeutics (Member) |
1996 - Present AHA Council for High Blood Pressure Research Research (Fellow) |
2012 - Present Organization for the Study of Sex Differences (Member) |
2016 - Present American Association of University Women (Member) |
2019 - Present International Association of Medical Science Educators (IAMSE) (Member) |
2020 - Present AAMC (Member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorial Board |
2006 - 2018 Journal of Pharmacology & Experimental Therapeutics |
Journal Review |
Cardiovascular Drugs and Therapy |
Journal of Lipid Research |
Atherosclerosis |
Biochimica et Biophysica Acta - Lipids and Lipid Metabolism |
General Pharmacology |
Journal of Cardiovascular Pharmacology |
Journal of Pharmacology and Experimental Therapeutics |
Physiological Genomics |
American Journal of Physiology |
Hypertension |
Placenta |
Prostaglandins and Other Lipid Mediators |
British Journal of Pharmacology |
European Journal of Pharmacology |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
1998 - 1999 Member, Peer Review Committee, Northland Affiliate, AHA |
2012 - 2015 Member, Search Committee for Regional Campus Deans, MCW |
2013 - 2016 Member, Women's Faculty Council, MCW |
2014 - 2016 Chair, Faculty Credentials Committee, MCW |
2016 - 2017 Vice-Chair, Academic Standing and Professionalism Committee, MCW |
2016 - 2017 Chair, Council for Women's Advocacy, MCW |
2016 - 2020 Member, Teaching, Vision and Brand Strategy Experience Team, MCW |
2016 - 2017 Member, MCW Leadership Academy, MCW |
2017 Member, Search Committee for Pharmacologist-School of Pharmacy, MCW School of Pharmacy |
2017 - 2018 Chair, Council for Women's Advocacy, MCW |
2018 - 2019 Member, Search Committee for Chair of Family and Community Medicine, MCW |
2018 Chair, Task Force on Grading Change to U/S in Preclinical Years, MCW |
2020 - 2021 Vice-President, Faculty Council, MCW |
2021 - Present Member, Pharmacology Education Committee, MCW |
2021 - 2022 Senior Vice President, Faculty Council, MCW |
2022 - 2023 member, Search Committee for Dean of Graduate School, MCW |
2022 - 2023 President, Faculty Council |
2022 - Present Vice-Chair, Academic Standing and Professionalism Committee, MCW |
2023 - Present Governance, Faculty Council, MCW |
2023 - Present Member, Search Committee for Director of Institute for Health and Equity, MCW |
2025 - Present Co-Director, Academic Excellence and Success Workgroup, Graduate School, Medical College of Wisconsin |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2002 Ad Hoc Reviewer, Health Research Board, Ireland |
2002 Ad Hoc Reviewer, VA Grant Review |
2006 Ad Hoc Reviewer, Kentucky Science and Engineering Foundation |
2009 Ad Hoc Reviewer, Challenge Grants, NIH, RIBT Study Section |
2009 - Present Reviewer, Vascular Biology Section, AHA |
2010 - Present Ad Hoc Reviewer, NIH, RIBT Study Section |
2012 Innovative Research Grant Review, AHA |
2015 - Present Reviewer, Lung Biology Peer Review, AHA |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
Second Workshop on Endothelium-Derived Hyperpolarizing Factor, Abbaye des Vaux de Cernay, France, 06/1998 |
Third Workshop on Endothelium-Derived Hyperpolarizing Factor, Abbaye des Vaux de Cernay, France, 06/2000 |
National |
Department of Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, 05/1993 |
Winter Eicosanoid Conference 2000, Baltimore, MD, 03/2000 |
EDHF: chemical nature and sites of action, Experimental Biology 2001; The American Physiological Society Symposia, Orlando, FL, 04/2001 |
University of North Texas State Health Science Center, Department of Integrative Physiology, Fort Worth, TX, 03/2003 |
Department of Pediatrics, Wake Forest University School of Medicine, 03/2005 |
Department of Pharmacology, Rush University Medical Center, Chicago, IL, 06/2010 |
Association of Moral Education, St. Louis, Missouri, 11/03/2017 |
SL Pfister, DJ Cipriano, "Faculty Training for Supporting our Students", 2024 AAMC Central GEA/GSA/OSR Regional Conference, Milwaukee, 2024 |
DJ Cipriano, R Narayan, J Kusch, SL Pfister, Centralizing Academic Accommodations: Promoting Inclusivity and Wellbeing in Medical Education, 2025 AAMC Central GEA/GSA/OSR Regional Conference, Detroit Michigan, 2025 |
Local |
Cardiovascular Research Center, Endothelial Cell Biology Symposium, MCW, 01/1993 |
Department of Physiology, MCW, 11/1994 |
Department of Anesthesiology, Veterans Affairs Medical Center, Milwaukee, WI, 04/1995 |
Women's Health Research Program, Department of Ob-Gyn, MCW, 11/16/2011 |
Panel Discussion on Running a Lab, ADVANCE-WFC, MCW, 2015 |
Science Needs More Females in the Laboratory (and not just humans), Kaleidoscope-A Research Forum with a Diversity Lens, Medical College of Wisconsin, 03/30/2016 |
Vascular Thromboxane Receptors, Atherosclerosis & Thrombosis Signature Program Meeting, MCW, 11/21/2016 |
Estrogen, 15-Lipoxygensae, Pulmonary Vascular Function, Atherosclerosis & Thrombosis Signature Program Meeting, MCW, 02/14/2017 |
Estrogen Paradox Understanding Female Predominance in Pulmonary Hypertension, ATVB Signature Program Meeting, MCW, 02/19/2018 |
Women in Science Improve the Health of Women, Osher Lifelong Learning Institute, University of Wisconsin-Milwaukee, 11/15/2019 |
Sex AS A Biological variable in Cardiovascular diseases, CVC Atherosclerosis, Thrombosis, and Vascular Biology Signature Program Meeting, MCW, 05/24/2021 |
K.Kaljo, H. Ellinas, S. Pfister, K. Quirk, Teaching with Inclusive Materials, Pathology Educational Development Session, MCW, 06/18/2021 |
K.Kaljo, H. Ellinas, S. Pfister, K. Quirk, : Fostering a Teaching Practice that Embodies Cultural Humility and Responsiveness, Pathology Educational Development Session, MCW, 11/03/2021 |
My Resume of Failures, Work-Life Fusion Group, MCW, 06/17/2022 |
SL Pfister, C Weaver, K Kaljo, Piloting Patient-Based Discussions in Discovery Curriculum:
Lessons Learned to Inform MCWfusion, Perspectives from Students and Faculty, Connection Cafe, MCW, 01/05/2023 |
SL Pfister, D Cipriano, Save our Students (SOS), MCWfusion Faculty Development Retreat Research Conference, MCW, 07/12/2023 |
SL Pfister D Cipriano, Supporting our Students Student Mental Health Presentation for SOP, School of Pharmacy Faculty Training, MCW, 08/2023 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
Regional |
Sandra Pfister, PhD, Joseph Block, MD, Chelsea Weaver, PhD, Anoop Singh, MD, Ryan Hillmer, PhD, Jazmin Candelario, Antonio Webster, The Future of Medical Education: Balancing In-Person and Webcast Instruction, Innovations in Healthcare Education Research, Milwaukee, 09/17/2024 |
SL Pfister, D Cipriano, "Faculty Training for Supporting our Students", Central Group on Education Affairs (CGEA), Milwaukee, 2024 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
1994 - 2002 Member, Animal Care Committee |
1996 - 1998 Member, Graduate Student Welfare Committee |
1997 - 2000 Member, Academic Standing Committee |
1999 - 2001 Member, Graduate Student Curriculum Committee |
2001 - 2003 Member, Graduate Student Awards Committee |
2006 - Present Alternate Member, Institutional Animal Care and Use Committee |
2006 - 2017 Member, Graduate School Interdisciplinary Program Recruiting Committee |
2007 - 2010 Member, Faculty Benefits Committee |
2011 - 2016 Member, Scholarly Activities Work Group |
2012 - Present Member, Academic Standing and Professionalism Committee |
2012 - 2023 Member, Pharmacology Content Expert Heme-Lymph |
2013 - 2015 Member, Search Committee for Campus Dean, Community Medical Education Program |
2013 - 2016 Member, Council for Women's Advocacy |
2013 - 2016 Member, Faculty Credentials Committee |
2014 - 2022 Member, Curriculum and Evaluation Committee |
2016 - 2019 Member, Keywords Work Group |
2017 - 2020 Member, Student-Directed Learning Work Group |
2018 - 2022 Member, Task Force on #MeToo |
2018 - 2019 Member, Search Committee for Chair of Family Medicine and Community Health |
2019 Chair, Task-Force to Implement Pass-Fail |
2019 - Present member, Advancing Women |
2019 member, Evaluation Task Force |
2019 - Present Vice Chair, Graduate School CEC |
2019 - Present member, MCW Suicide Prevention Council |
2020 - 2022 Member, Ad Hoc Committee on Graduate School Holistic Admissions |
2020 - Present Member, Graduate Education Committee-Pharmacology |
2021 - Present Chair, Student Welfare -Graduate Students |
2022 - 2024 Member, Search Committee for Dean of Graduate School |
2023 - Present Member, Search Committee for Institute for Health and Equity Director |
2024 - Present Member, Search Committee for Regional Campus Dean-Central Wisconsin |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
1993 - 2023 Principles of Drug Action formally Medical Pharmacology, Prostaglandins |
1993 - 2012 Medical Pharmacology, Antihyperlipidemic Drugs |
1993 - 2023 Principles of Drug Action formally Medical Pharmacology, Thombolytics and Anticoagulants |
1993 - 2023 Principles of Drug Action formally Medical Pharmacology, Nonsteroidal Antiinflammatory Drugs |
1993 - 2023 Principles of Drug Action formally Medical Pharmacology, Histamine |
1993 - 2023 Principles of Drug Action formally Medical Pharmacology, Introdution to the Pharmacology of Inflammation |
11/2010 TBL sessions for M1 Integrated Pilot Curriculum Treatment of Back Pain |
01/2011 TBL sessions for M1 Integrated Pilot Curriculum Pharmacological Treatment of Acute Myocardial Infarction |
02/2011 TBL sessions for M1 Integrated Pilot Curriculum Treatment of Asthma |
01/2012 Treatment of Coagulation Disorders in M2 Pilot Curriculum |
04/2012 Treatment of Gout; Symptoms Module, M2 Pilot Curriculum |
2013 - 2023 M2 Cardiovascular Unit Pharmacology of Antilipidemics |
2013 - 2023 M2 Musculoskeletal Unit Pharmacology of Gout, RA and OA |
2013 - 2023 M2 Cardiovascular Unit Treatment of Acute Coronary Syndrome/Thrombolytics |
2013 - 2023 M2 Symptoms Unit Joint Pain |
2014 - 2023 M2 Cardiovascular Unit Women and CV Disease |
2014 - 2023 M2 Renal-Respiratory Unit Pharmacology of Asthma |
2015 - 2023 M2 Symptoms Unit Dyspnea |
2015 - 2023 M2 Symptoms Unit Wheezing |
2016 - 2024 Upper GI Pharmacology in M2 GI Unit |
2019 - Present Pediatric Integrating Cases for M4 Students |
2023 - Present MCWfusion Foundations of Medicine Block Introduction to Pharmacology |
2023 - Present MCWfusion GI-N Block Therapeutic Intervention in the Upper Gastrointestinal Tract |
2023 - Present MCWfusion Foundations of Medicine Block Overview of Antimicrobial Therapy |
2023 - Present MCWfusion Musculoskeletal Skin Block Therapies for Gout, Rheumatoid Arthritis & Osteoarthritis |
2023 - Present MCWfusion Musculoskeletal Skin Block NSAIDS and Acetaminophen |
2023 - Present MCWfusion Hematology – Immunology Block Anti-platelet Drugs |
2023 - Present MCWfusion Hematology – Immunology Block Anticoagulant Drugs |
2024 - Present MCWfusion Cardiovascular Block CHA2DS2-VASc and Anticoagulants
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2024 - Present MCWfusion Respiratory Block Drugs Used for Asthma and COPD |
2024 - Present MCW Fusion Cardiovascular Block Pharmacology of Hyperlipidemias |
2024 - Present MCWfusion Cardiovascular Drugs Treatment of Hypertension |
2024 - Present MCWfusion Cardiovascular Block Anti-thrombotic Pharmacological Treatments for Ischemic Heart Disease & Acute Coronary Syndrome |
2024 - Present MCWfusion Respiratory Block Drugs Used for Allergies, Cough, Respiratory Infections |
2024 - Present MCWfusion Cardiovascular Block Women and Heart Disease |
Graduate Student Education |
1994 - 2019 Graduate Student Pharmacology Lectures, Signaling by Phospholipases and Cyclooxygenase-1 and -2 |
1994 - 2015 Graduate Student Pharmacology Lectures, Phospholipases |
1994 - Present Graduate Student Pharmacology Lectures, Immunoassays |
1994 - Present Graduate Student Pharmacology Lectures, Eicosanoids as Second Messengers |
1994 - 2019 Graduate Student Pharmacology Lectures, Statins as Cholesterol-Lowering Drugs in Cardiovascular Disease |
1998 Course Director for Principles of Drug Action I- Receptors |
2004 - 2006 Biochemistry of the Cell/ Mechanisms of cellular signaling, Gene regulation of cholesterol metabolism |
2004 - 2006 Biochemistry of the Cell/ Mechanisms of cellular signaling, Steroid metabolism |
2006 - 2018 Biochemistry of the Cell/ Mechanisms of cellular signaling, Atherosclerosis; role of cholesterol and inflammation, |
2015 - Present Drug Discovery:Therapeutic Antibodies |
2019 - 2022 IDP-Foundations in Biomedical Sciences:Ligands as Initiators of Cell Signaling |
2019 - Present Understanding Cell Signaling Through Therapeutic Drugs Statins as Cholesterol-Lowering Drugs in Cardiovascular Disease |
2019 - Present IDP Foundations in Biomedical Science: Cyclooxygenases: COX-1 and COX-2 |
2024 - Present Co-Director; SEED-Skiils Enhancement through Experiential Development |
2024 - Present Co-Director Understanding Cell Signaling through Therapeutic Drugs |
Resident and Fellow Education |
2014 - 2018 New Oral Anticoagulants |
Continuing Medical Education |
2019 - 2024 Kinetic3 "Remediation of Medical Learners" |
2020 - 2024 Kinetic, Implicit Bias for Teaching Excellence |
2020 Kinetic, "Curriculum and Course Design" |
2020 - 2024 Kinetic3 "Supporting our Students" |
Community/Lay Public |
1989 - 1991 Pharmacology in the Physician's Assistants Program, Antihypertensive Drugs |
1989 - 1991 Pharmacology in the Physician's Assistants Program, Diuretics |
1995 - 1998 Mini-Medical School |
2019 - Present Kinetic3 Teaching Academy |
EXTRAMURAL TEACHING: |
Community/Lay Public |
1996 - 1999 Marquette University, Pharmacology in the Marquette University Graduate Nursing Program, Diuretics |
1996 - 1999 Marquette University, Pharmacology in the Marquette University Graduate Nursing Program, Antihypertensive Drugs |
1996 - 1999 Marquette University, Pharmacology in the Marquette University Graduate Nursing Program, Antihyperlipidemic Drugs |
PROGRAMMATIC DEVELOPMENTS: |
Educational Programs |
Faculty |
06/2014 Exploring Effective Teaching Techniques in Discovery Curriculum, WFC-FCDC sponsored |
03/30/2016 Presentation on Women's Health-Kaleidoscope |
08/2016 - 08/2017 Capstone Project "Development of a Sex and Gender Medicine Curriculum for MCW Students" MCW Leadership Academy |
06/2017 Designing Student-Centered Learning Experiences as part of Summer Institute at Olin College Collaboratory |
2019 - Present Graduate Student Well-Being Initiative |
2023 - Present HLC Quality Improvement Initiative |
COMMUNITY SERVICE ACTIVITIES: |
09/1997 - 2018 Teach catechism-ESCYM, Milwaukee, WI |
04/09/2016 - Present Engaging Girls in Science; Prep-Pro Workshop (Preparing to be a Professional). |
2016 - Present Member, Women in Science |
11/15/2019 Women in Science Improve the Health of Women, Osher Lifelong Learning Institute, University of Wisconsin-Milwaukee, |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Keeton TK, Pfister S. The effect of the antihypertensive drug labetalol on renin release in the conscious rat Federation Proceedings. 1980;39(3 II):4824. |
2. Pfister SL, Keeton TK. The mechanism of yohimbine-induced renin release in the conscious rat Federation Proceedings. 1981;40(3 I). |
3. Pfister SL, Keeton TK. Rauwolscine-induced renin release in the conscious rat Federation Proceedings. 1982;41(4):5618. |
4. Pfister SL, Biediger AM, Lopez MD, Keeton TK. Effect of renal denervation and adrenalectomy on yohimbine-induced renin release in the conscious rat Federation Proceedings. 1984;43(4). |
5. Pfister, S.L., Keeton, T.K.: Yohimbine induces sympathetically-mediated renin release in the conscious rat. Eur. J. Pharmacol. 97:247-255, 1984. |
6. Keeton TK, Pfister SL. Yohimbine amplifies the neuroendocrine effects of hydralazine and prazosin in the conscious rat Federation Proceedings. 1984;43(4). |
7. Keeton TK, Biediger AM, Pfister SL. A comparison of the hemodynamic and neuroendocrine effects of α<inf>2</inf>-adrenoceptor antagonists Federation Proceedings. 1985;44(5). |
8. Pfister SL, Hubbard JW, Keeton TK. The measurements of yohimbine in rat brain and plasma using HPLC Federation Proceedings. 1985;44(5). |
9. Pfister, S.L., Keeton, T.K.: The mechanism of yohimbine-induced renin release in the conscious rat. Naunyn-Schmeideberg's Arch. Pharmcol. 337:35-46, 1988. |
10. Hubbard, J.W., Pfister, S.L., Biediger, A.M., Herzig, T.C, Keeton, T.K.: The pharmacokinetic properties of yohimbine in the conscious rat. Naunyn-Schmeid. Arch. Pharmacol. 337:583-587, 1988. |
11. Pfister, S.L., Keeton, T.K.: Angiotensin II contributes to blood pressure maintenance in conscious rats treated with yohimbine. Eur. J. Pharmacol. 149:377-380, 1988. |
12. Pfister, S.L., Schmitz, J.M., Willerson, J.T.,Campbell, W.B.: Characterization of arachidonic acid metabolism in Watanabe Heritable Hyperlipidemic (WHHL) and New Zealand White (NZW) rabbit aortas. Prostaglandins 36:515-532, 1988. |
13. Wines, P.A., Schmitz, J.M., Pfister, S.L., Clubb, F.J., Buja, L.M., Willerson, J.T., Campbell, W.B.: Augmented vasoconstrictor responses to serotonin precede the development of atherosclerosis in the aorta of the WHHL rabbit. Arteriosclerosis 9:195-202, 1989. |
14. Pfister, S.L., Rosolowsky, M., Schmitz, J.M., Clubb, F.J., Jr., Campbell, W.B.: Eicosapentaenoic acid alters vascular reactivity and platelet adhesion in Watanabe Heritable Hyperlipidemic rabbits. Eur. J. Pharmacol. 161:85-89, 1989. |
15. Rosolowsky, M., Pfister, S.L., Buja, L.M., Clubb, F.J., Campbell, W.B.: Method of removal of aortic endothelium affects arachidonic acid metabolism & vascular reactivity. Eur. J. Pharm. 193:293-300, 1990. |
16. Pfister, S.L., Falck, J.R., Campbell, W.B.: Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta. Am. J. Physiol. 261:H843-H852, 1991. |
17. Pfister, S.L., Campbell, W.B.: Arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta. Hypertension 20:682-689, 1992. |
18. Buzzard, C.J., Pfister, S.L., Campbell, W.B.: Endothelial dependent contractions in rabbit pulmonary artery are mediated by thromboxane A2. Circ. Res. 72:1023-1034, 1993. |
19. Buzzard, C.J., Pfister, S.L., Halushka, P.V., Campbell, W.B.: Decrease in vascular thromboxane A2 receptors in a subgroup of rabbits unresponsive to a thromboxane A2 mimetic. Am. J. Physiol. 266:H2320-H2326, 1994. |
20. Pfister, S.L., Spitzbarth, N., Edgemond, W., Campbell, W.B. : Vasorelaxation by an endothelium-derived metabolite of arachidonic acid. Am J. Physiol. 270:H1021-1030, 1996. |
21. Pfister, S.L and Campbell, W.B.: Role of endothelium-derived metabolites of arachidonic acid in the enhanced pulmonary artery contractions in female rabbits. Hypertension 27:43-48, 1996. |
22. Pfister SL, Campbell WB. Platelet thromboxane a2 (TXA2) mediates arachidonic acid (AA)-induced contractions in rabbit pulmonary artery (PA) FASEB Journal. 1996;10(3). |
23. Pfister, S.L.,Campbell, W.B.: Reduced pulmonary artery vasoconstriction to methacholine in cholesterol-fed rabbits. Hypertension 27[part 2]:804-810, 1996. |
24. Pfister, S. L. ,Campbell, W.B.: Contribution of arachidonic acid metabolites to reduced norepinephrine induced contractions in hypercholesterolemic rabbit aortas. J. Cardio. Pharm. 28:784-791, 1996. |
25. Pfister, S.L., Kotulock, D.A., Campbell, W.B.: Vascular smooth muscle thromboxane A2 receptors mediate arachidonic acid-induced sudden death in rabbits. Hypertension 29:303-309, 1997. |
26. Pfister, S.L., Deinhart, D., Campbell, W. B.: Methacholine-induced contraction of rabbit pulmonary artery: Role of platelet-endothelial transcellular thromboxane synthesis. Hypertension 31:206-212, 1998. |
27. Pfister, S.L., Spitzbarth, N. Nithipatikam, K., Edgemond, W, Falck, J.R., Campbell, W.B.: Identification of the 11,14, 15- and 11,12,15-trihydroxyeicosatrienoic acid as an endothelium-derived relaxing factors of rabbit aorta. J. Biol. Chem. 273: 30879-30887, 1998. |
28. Fike, C.D., Pfister, S.L., Kaplowitz, M.R., Madden, J.A.: Cycloxygenase contracting factors and altered pulmonary vascular responses in chronically hypoxic newborn pigs, J. Appl. Physiol. 92:67-74, 2002. |
29. Sherman, T.S., Chambliss, K.L., Gibson, L.L., Pace, M.C., Mendelsohn, M.E., Pfister, S.L., Shaul, P.W.: Estrogen acutely activates prostacyclin synthesis in ovine fetal pulmonary artery endothelium. Am J Respir. Cell Mol. Biol. 26:610-616, 2002. |
30. Pfister, S.L., Hughes, M.J., Rosolowsky, M., Campbell, W.B.: Role of contaminating platelets in thromboxane B2 synthesis in primary cultures of human umbilical vein endothelial cells, Prostaglandins other Lipid Med. 70:39-49,2002. |
31. Fike, C.D.,Kaplowitz, M.R., Pfister, S.L.: Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs, Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L316-323, 2003. |
32. Pfister, S.L., Spitzbarth, N., Nithipatikom, K., Falck, J.R., Campbell, W.B.: Metabolism of 12- hydroperoxyeicosatetraenoic acid to vasodilatory trioxilin C3 by rabbit aorta. Biochim Biophys Acta.1622:6-13., 2003. |
33. Campbell, W.B., Spitzbarth, N., Gauthier, K.M., Pfister, S.L.: 11,12,15-Trihydroxyeicosatrienoic acid mediates ACh-induced relaxations in rabbit aorta. Am J Physiol Heart Circ Physiol.285:H2648-56, 2003. |
34. Pfister, S.L., Spitzbarth ,N., Zeldin, D.C., Lafite, P., Mansuy, D., Campbell, W.B.: Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450. Arch Biochem Biophys.420:142-52, 2003. |
35. Pfister, S.L.: The role of platelet microparticles in the production of thromboxane by rabbit pulmonary artery. Hypertension 43:428-433, 2004. |
36. Rademacher, D.J., Kearn, C.S., Carrier,E.J., Patel, S., Delgado, M., Barkmeier, A., Klick, D.E., Breese, N.M., Pfister, S.L., Nithipatikom, N., Campbell, W.B., Hillard, C.J.: Production of hydroxyeicosatetraenoic acids (HETEs) and prostaglandins by a novel rat microglial cell line, J Neuroimmunol,149:130-141, 2004. |
37. Carrier EJ, Kearn CS, Barkmeier AJ, Breese NM, Yang W, Nithipatikom K, Pfister, S.L., Campbell, W.B., Hillard, C.J.: Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor dependent mechanism, Mol Pharmacol, 65:999-1007, 2004 |
38. Pfister, S.L., Pratt, P, Kurian, J, Campbell, W.B.: Glibenclamide inhibits thromboxane-mediated vasoconstriction by thromboxane receptor blockade. Vascular Pharmacol, 40:285-292, 2004 |
39. Fike CD, Kaplowitz MR, Zhang Y, Pfister SL.Cyclooxygenase 2 and an early stage of chronic hypoxia-induced pulmonary hypertension in newborn pigs. J Appl Physiol. 98:1111-1118, 2005. |
40. Pfister, SL: Aortic thromboxane receptor deficiency alters vascular reactivity in cholesterol-fed rabbits Atherosclerosis, 189:358-363, 2006. |
41. Pfister, SL: Role of lipoxygenase metabolites of arachidonic acid in enhanced pulmonary artery contractions of female rabbits, Hypertension, 57:825-832, 2011. PMID: 21300669; PMCID: PMC3073701. |
42. Pfister SL. Characterization of endothelial thromboxane receptors in rabbit aorta. Prostaglandins Other Lipid Mediat. 87:54-61. 2008 |
43. Pfister, SL, Nithipatikom, K, Campbell, WB: Role of superoxide and thromboxane receptors in acute angiotensin II-induced vasoconstriction of rabbit vessels. Amer J Physiol Heart Circ Physiol, 300(6):H2064-7, 2011 PMID:21460202. |
44. Fike, CD, Aschner, JL, Kaplowitz, MR, Zhang, Y, Pfister, SL: Pulmonary arterial responses to reactive oxygen species are altered in newborn piglets with chronic hypoxia-induced pulmonary hypertension,Pediatric Research, 70(2):136-41, 2011. PMID:21516056 |
45. Pfister, S.L., Somberg, L., Lowry, T., Gao, Y. Medhora, M. and E.R. Jacobs. Mechanisms underlying increased reactivity of pulmonary arteries contralateral to a localized high-flow anastomosis. J Thor Cardio Surg, 141:425-431, 2011. PMID: 21075383 PMCID:PMC3052931. |
46. Fike, C.D., Pfister, S.L., Slaughter, J.C., Kaplowitz, M.R., Zhang, Y., Zeng, H., Frye, N.R. and Aschner, J.L. Protein complex formation with heat shock protein 90 (Hsp90) in chronic hypoxia-induced pulmonary hypertension in newborn piglets. Amer J Physiolol,Oct;299(4):H1190-204. Epub 2010 Aug 6.2010 PMID:20693398 |
47. Pfister S, Somberg L, Lowry T, Gao Y, Medhora M, Jacobs ER. Mechanisms underlying increased reactivity of pulmonary arteries contralateral to a localized high-flow anastomosis. J Thorac Cardiovasc Surg. 2011 Feb;141(2):425-31. PMCID: PMC3052931 |
48. Siangjong,L, Gauthier,KM Pfister,SL, Smyth, EM and Campbell, WB. Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries,Amer J Physiol 304(3):H382-92,2013 PMCID:PMC3774504
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49. Ma S, Yin N, Qi X, Pfister SL, Zhang MJ, Ma R, Chen G. Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER). Oncotarget. 2015 May 30;6(15):13320-33. PMCID: PMC4537017 |
50. Pfister SL, Klimko PG, Conrow RE. (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid: A stable isomer of 15(S)-HETE that retains key vasoconstrictive and antiproliferative activity. Prostaglandins Other Lipid Mediat. 2016 Mar;123:33-9. PMCID: PMC4893888 |
51. Park SK, Herrnreiter A, Pfister SL, Gauthier KM, Falck BA, Falck JR, Campbell WB. GPR40 is a low-affinity epoxyeicosatrienoic acid receptor in vascular cells. J Biol Chem. 2018 Jul 06;293(27):10675-10691. PMCID: PMC6036206 |
52. Pfister, SL, Mechanism of 15-HETE-induced contractions in female and male pulmonary arteries. in preparation, 2024 |
53. Kriska T, Herrnreiter A, Pfister SL, Adebesin A, Falck JR, Campbell WB. Macrophage 12(S)-HETE Enhances Angiotensin II-Induced Contraction by a BLT2 (Leukotriene B<sub>4</sub> Type-2 Receptor) and TP (Thromboxane Receptor)-Mediated Mechanism in Murine Arteries. Hypertension. 2022 Jan;79(1):104-114. PMCID: PMC8849474 |
54. Kling JM, Sleeper R, Chin EL, Rojek MK, McGregor AJ, Richards L, Mitchell AB, Stasiuk C, Templeton K, Prasad J, Pfister S, Newman CB. Sex and Gender Health Educational Tenets: A Report from the 2020 Sex and Gender Health Education Summit. J Womens Health (Larchmt). 2022 Jul;31(7):905-910. PMCID: PMC9483836 |
55. Trieglaff K, Zamzow MJ, Sutherland B, Farkas A, Pfister S. Audit of Sex and Gender Medicine Topics in Preclinical School of Medicine Curriculum. WMJ. 2023 Sep;122(4):243-249. |
56. Kriska T, Natarajan J, Herrnreiter A, Park SK, Pfister SL, Thomas MJ, Widiapradja A, Levick SP, Campbell WB. Cellular metabolism of substance P produces neurokinin-1 receptor peptide agonists with diminished cyclic AMP signaling. Am J Physiol Cell Physiol. 2024 Jul 01;327(1):C151-C167. PMCID: PMC11371325 |
Books, Chapters, and Reviews |
1. Pfister, SL, Spitzbarth, N, Nithipatikom, K, Edgemond, WS, Campbell, WB: Endothelium-derived eicosanoids from lipoxygenase relax the rabbit aorta by opening potassium channels. In Endothelium- Dependent Hyperpolarizations, PM Vanhoutte, Ed., Harwood Acad Publishers, Canada, p.17-28, 1999. |
2. Pfister, S.L., Spitzbarth, N., Gauthier, K.M.,Campbell, W.B.: Identification of 11,12,15-trihydroxyeicosatrienoic acid as the mediator of acetylcholine- and arachidonic acid-induced relaxations in the rabbit aorta. In Endothelium-Dependent Hyperpolarizations, PM Vanhoutte, Ed., Taylor & Francis, London,p 239-248, 2001. |
3. Pfister, S.L., Gautheir, K.M. Campbell, W.B: Vascular pharmacology of epoxyeicosatrienoic acids. In Advances in Pharmacology, PM Vanhoutte, Ed. Vol. 60:27-59, 2010 |
Abstracts |
1. Pfister, S.L. and Keeton, T.K.: Rauwolscine-induced renin release in the conscious rat. Fed. Proc. 41:1232, 1982. |
2. Pfister, S.L., Biediger, A.M., Lopez, M.D. and Keeton, T.K.: The hemodynamic and endocrine effect of yohimbine and rauwolscine in conscious rats. Fed. Proc. 42:617, 1983. |
3. Lopez, M.D., Pfister, S.L., Brennan, T.J. and Haywood, J.R.: The effect of yohimbine on thirst. Fed. Proc. 42:610, 1983. |
4. Pfister, S.L. and Keeton, T.K.: A comparison of the hemodynamic and endocrine effects of yohimbine and rauwolscine in the conscious rat. Prog. Neuro-Psychopharmacol. (Suppl):248-249, 1983. |
5. Keeton, T.K. and Pfister, S.L.: Potentiation by yohimbine of the endocrine effects caused by hydralazine in the conscious rat. Prog. Neuro-Psychopharmacol. (Suppl):187, 1983. |
6. Pfister, S.L., Biediger, A.M., Lopez M.D. and Keeton, T.K.: Effect of renal denervation and adrenalectomy of yohimbine-induced renin release in the conscious rat. Fed. Proc. 43:811, 1984. |
7. Keeton, T.K. and Pfister, S.L.: Yohimbine amplifies the neuro-endocrine effects of hydralazine and prazosin in the conscious rat. Fed. Proc. 43:813, 1984. |
8. Pfister, S.L., Hubbard, J.W. and Keeton T.K.: Measurements of yohimbine in rat brain and plasma using HPLC. Fed. Proc. 44:1117, 1985. |
9. Keeton, T.K., Biediger, A.M. and Pfister, S.L.: A comparison of the hemodynamic and neuroendocrine effects of 2-adrenoreceptor antagonists. Fed. Proc. 44:1571, 1985. |
10. Pfister, S.L., Schmitz, J.M., Willerson, J.T. and Campbell, W.B.: Metabolism of arachidonic acid in 1 yr old New Zealand white (NZW) and Watanabe heritable hyperlipidemic (WHHL) rabbit aortas. Fed. Proc. 45:456, 1986. |
11. Pfister, S.L., Schmitz, J.M., Willerson, J.T. and Campbell, W.B.: Synthesis of monohydroxyeicosatetraenoic acids (HETEs) in Watanabe Heritable Hyperlipidemic (WHHL) and New Zealand White (NZW) rabbit aortas. Fed. Proc. 46:375, 1987. |
12. Pfister, S.L. and Campbell, W.B.: Lipoxygenase and epoxygenase metabolism of arachidonic acid in cholesterol-fed rabbit aorta. Circulation 78:II-338, 1988. |
13. Pfister, S.L. and Campbell, W.B.: Comparison of arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta. FASEB J. 4:A310, 1990. |
14. Rosolowsky, M., Pfister, S.L., Buja, L.M. and Campbell, W.B.: Method of removal of endothelium affects synthesis of lipoxygenase metabolites in rabbit aorta. FASEB J. 4:A310, 1990. |
15. Pfister, S.L., Buzzard, C.J. and Campbell, W.B.: Endothelial dependent contracting factor released by arachidonic acid in rabbit pulmonary artery. The Physiologist 34:253, 1991. |
16. Pfister, S.L., Buzzard, C.J. and Campbell, W.B.: Decrease in vascular thromboxane receptors in a subgroup of nonresponding rabbits. Presented at International Conference on Prostaglandins and Related Compounds. 1992. |
17. Edgemond, W.S., Pfister, S.L. and Campbell, W.B.: Characterization of an unknown endothelial metabolite from rabbit aorta. Presented at the International Conference on Prostaglandins and Related Compounds. 1992. |
18. Pfister, S.L. and Campbell, W.B. : Enhanced endothelium-dependent contractions in pulmonary arteries from female rabbits. 48th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 1994. |
19. Pfister, S.L. and Campbell, W.B. Reduced pulmonary artery vasoconstriction in cholesterol-fed rabbits. 49th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 1995. |
20. Pfister, S.L. and Campbell, W.B. Platelet thromboxane A2 mediates arachidonic acid-induced contractions in rabbit pulmonary artery. Experimental Biology, 1996. |
21. Pfister, S.L., Kotulock, D.A. and Campbell, W.B.: Vascular thromboxane A2 receptor-deficient rabbits have lower blood pressure and are protected from arachidonic acid-induced sudden death. 50th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 1996. |
22. Pfister, S.L., Deinhart, D and Campbell, W.B. : The role of platelets in arachidonic acid-and methacholine-induced contractions of rabbit pulmonary arteries. 51st Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 1997. |
23. Pfister, S.L., Spitzbarth, N., Nithipatikom, K., Edgemond, W.S. and Campbell, W.B. : Identification of endothelium-derived lipoxygenase metabolites of arachidonic acid that relax rabbit aorta. 52nd Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 1998. |
24. Le, T.H., Thomas, D., Coffman, T.M. and Pfister, S.L.: Vascular unresponsivenness to thromboxane A2 is associated with a polymorphism at the thromboxane receptor gene locus. . 53rd Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 1999. |
25. Gauthier, K.M., Pfister, S.L., Spitzbarth, N, Rusch, N.J. and Campbell, W.B.: Role of 11,12,15-trihydroxyeicosatrienoic acid as a new endothelium-derived relaxing factor. 54th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 2000. |
26. Fike, C.D., Kaplowitz, M.R. and Pfister, S.L.. Prostacyclin production and synthase abundance are decreased in small pulmonary arteries of chronically hypoxic newborn piglets. American Thoracic Society, 2001. |
27. Pfister, S.L., Spitzbarth, N., Gauthier, K. and Campbell, W.B.: Identification of 11,12,15-trihydroxyeicosatrienoic acid as the mediator of acetylcholine- and arachidonic acid-induced relaxations in rabbit aorta, Experimental Biology, 2001 |
28. Pfister, S.L., Kurian, J., Pratt, P., and Campbell, W.B.: Inhibition of thromboxane-mediated vasoconstriction by sulfonylureas, 55th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 2001. |
29. Pfister, S.L.: Altered vascular responses in cholesterol-fed rabbits lacking vascular thromboxane receptors, XV Scientific Meeting of the Inter-American Society of Hypertension and Council for High Blood Pressure Research, 2003 |
30. Pfister, S.L. The role of platelet microparticles in the production of thromboxane by rabbit pulmonary artery 57th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 2003. |
31. Pfister, SL and Campbell, W.B. : Effect of angiotensin II in rabbits lacking vascular thromboxane receptors, 58th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 2004. |
32. Pfister, SL: Enhanced arachidonic acid(AA)-induced contractions in pulmonary arteries:role of 15-lipoxygenase and estrogen. 60th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 2006. |
33. Fike, CD, Kaplowitz, MR, Zhang, Y, Pfister, SL: Prostanoid production and pulmonary microvascular responses to hydrogen peroxide (H2O2) are altered in newborn piglets with chronic hypoxia-induced pulmonary hypertension. 8th World Congress for Microcirculation, 2007 |
34. Fike, CD, Ascher, JL, Kaplowitz, MR, Zhang, Y, Pfister, SL: Prostanoid production and vascular responses to hydrogen peroxide (H2O2) are altered in resistance level pulmonary arteries (PRA) of newborn piglets with chronic hypoxia-induced pulmonary hypertension. Society for Pediatric Research, 2009. |
35. Pfister, SL, Aggarwal, NT, Campbell WB: Hypoxia and pulmonary artery vascular function:role of gender; 63rd Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 2009. |
36. Pillay T and Pfister SL: Characterization of lipoxygenases (LOs) mediating gender-specific pulmonary artery (PA) vasoconstriction to arachidonic acid (AA) 64th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, 2010. |
37. Pfister, SL and Pillay, T: Sex-based differences in 15-lipoxygenase and airway reactivity FASEB J March 17, 2011 25:806.5 |
38. Pfister, SL A Novel Mechanism To Explain Enhanced Pulmonary Artery Vasoconstriction In Female Rabbits. Scientific Abstracts. Pulm Circ 2011;1:508; The 2011 Grover Conference - Risk Factors in Pulmonary Hypertension: Gender, Sex Hormones, Obesity, Novel Genetic Influences and Risk Factors Sedalia, Colorado, USA, 7-11 September, 2011 |
39. Pfister, SL. Potential role of estrogen in 15-hydroxyeicosatetranoic acid production and activity in human pulmonary artery endothelial cells. 2015 APS Conference:Cardiovascular, Renal and Metabolic Diseases:
Physiology and Gender, November 2015. |
40. T. Kriska, S. Pfister, W.B. Campbell. Macrophage 12-HETE enhances angiotensin-11 vasoconstriction through iso-thromboxane B2 release in murine aortas. FASEB J April 2017 31:827.18 |
41. S.Park, A. Herrnreiter, S. L. Pfister, J. R. Falck, and W.B. Campbell.
Characterization of GPR40 as a Low Affinity Epoxyeicosatrienoic Acid (EET) Receptor in Vascular Cells. FASEB J April 2017 31:827.6 |
42. S Pfister, J Kerschner, J Franco, B Hueston, C Maurana, J Raymond. How the Kern Institute is Leading US Medical School Change. 43rd Annual Association for Moral Education, St. Louis, MO November 2017. |
43. SL Pfister, AM Hines, AL Rabbitt, AJ Wagner, TP Webb. Student and Faculty Perception of Women’s Health and Sex and Gender Medicine Curriculum at the Medical College of Wisconsin (MCW), Sex and Gender Medicine Health Education Summit, Salt Lake City, Utah, April 2018 |
44. S Pfister, C Malmsten, S Twining, E Suelzer, P Hurlbut. Using Self-Directed Learning (SDL) to Teach Sex and Gender Medicine to Second-Year Medical (M2) Students, Sex and Gender Medicine Health Education Summit, Salt Lake City, Utah, April 2018 |
45. S Pfister, H Ludtke, K Scheel, K Dunisch and M Berger DAILY EXPOSURE TO ELECTROCARDIOGRAM (ECG)-RELATED PROBLEMS DURING CARDIOVASCULAR (CV) COURSE IMPROVED SECOND YEAR MEDICAL (M2) STUDENT CONFIDENCE AND PERFORMANCE IN ECG INTERPRETATION/ International Association of Medical Science Educators. Annual Meeting April 2020
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46. Tolo H, Conger RL, Magana V, Smoki JR, LaBodda SK,Polhemus SE, Pfister SL. Students take lead to educate faculty on the use of sex and gender terminology in pre-clinical courses. Sex and Gender Health Education Summit September 2020 |
47. K Kaljo K Marcdante R Treat B Thapa B Campbell S Pfister A Harrington
Changing Tides of Faculty Professional Development: Emphasizing Character and Caring in Pedagogy and Medical Education Research 2020 AAMC Medical Education Meeting Learn Serve Lead 2020: The Virtual Experience.
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48. Sutherland BL, Trieglaff K, Zamzow M, Johnson P, Rossman AH, Nwaelugo N, Mann R, Stamm K, Ark T, Pfister S. “Is a female always a woman and a male always a man? Sex and gender terminology in the M1 and M2 courses at the Medical College of Wisconsin; 2021 Sex and Gender Health Education (SGHE) Summit |
49. Zamzow M, Trieglaff K, Sutherland B, Stamm K, Ark T, Pfister S. “Sex and Gender Medicine in the First Year MD Curriculum at the Medical College of Wisconsin.” 2021 Sex and Gender Health Education (SGHE) Summit |
50. Trieglaff KM, Zamzow M, Sutherland B, Johnson P, Rossman AH, Nwaelugo N, Mann R, Stamm K, Ark T, Pfister S. “Sex and Gender Medicine (SGM) in the Second Year (M2) MD Curriculum at the Medical College of Wisconsin (MCW).” 2021 Sex and Gender Health Education (SGHE) Summit |
51. Dimmer, K, Mantsch, J Olsen, C, Ciezki, K, Auchampach, J, Borisy-Rudin, F, Pfister, S SEEDing Professional Growth: Integrating Flourishing and Experiential Learning in PhD Training. KNN 2025 Annual Conference, "Shaping the Future Together: Advancing Flourishing for All." Minneapolis, MN |
