CURRICULUM VITAE
Veronica H. Flood MD
Veronica H. Flood MD
Chief, Professor
Department of Pediatrics
Division of Hematology and Oncology - Pediatrics
Department of Pediatrics
Division of Hematology and Oncology - Pediatrics
OFFICE ADDRESS: |
Children’s Wisconsin - Milwaukee Hospital |
8915 W Connell Court |
Milwaukee, WI 53226 |
EDUCATION: |
08/1991 - 06/1995 AB in Biology Anthropology, Harvard College, Cambridge, MA |
08/1995 - 05/1999 MD, Tufts University School of Medicine, Boston, MA |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
06/1999 - 06/2002 Resident, Pediatrics, Phoenix Children's Hospital/Maricopa Medical Center, Phoenix, AZ |
07/2002 - 06/2005 Fellow, Pediatrics, Hematology/Oncology, Oregon Health & Science University, Portland, OR |
FACULTY APPOINTMENTS: |
07/2005 - 07/2006 Instructor, Pediatrics, Oregon Health & Science University, Portland, OR |
08/2006 - 06/2013 Assistant Professor, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI |
07/2013 - Present Associate Professor, Pediatrics, Section of Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI |
01/2016 - Present Associate Investigator, Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
01/2009 - 06/2012 Fellowship Hematology Rotation Coordinator, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI |
07/2011 - 06/2013 Educational Liaison, Pediatric Hematology Resident Elective, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI |
07/2012 - 06/2013 Associate Fellowship Director, Pediatrics, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI |
12/2015 - Present Chair, Medical Student Educaiton Committee, Pediatric, Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI |
HOSPITAL STAFF PRIVILEGES: |
07/2005 - 07/2006 Medical Staff, Oregon Health & Science University (OHSU), 3181 S.W. Sam Jackson Park Rd., Portland, OR 97239 |
07/2005 - 07/2006 Medical Staff, OHSU Doernbecher Children's Hospital, 3181 S.W. Sam Jackson Park Rd., Portland, OR 97239 |
08/2006 - Present Medical Staff, Hematology/Oncology/BMT, Children's Hospital of Wisconsin, 9000 W. Wisconsin Ave., Milwaukee, WI 53226 |
08/2006 - Present Medical Staff, Hematology, Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226 |
SPECIALTY BOARDS AND CERTIFICATION: |
Board Certified | Issue Date | Expiration |
American Board of Pediatrics | 10/2002 | 2014 |
American Board of Pediatrics - Hematology/Oncology | 11/2006 | 2026 |
Certificates | Issued By | Issue Date | Expiration |
BLS | AHA | 04/2010 | 04/2014 |
PALS | AHA | 04/2010 | 04/2014 |
Licensure | Number | Issue Date | Expiration |
Wisconsin Medical License | 07/26/2006 | 10/31/2025 | |
AWARDS AND HONORS: |
09/2003 - 06/2005 Human Investigations Program, OHSU |
07/2004 - 06/2005 Chief Pediatric Fellow - elected chief of all pediatric fellows, OHSU |
09/2004 - 08/2010 Pediatric Research Loan Repayment Program, National Institutes of Health |
06/2005 "Outstanding Research by a Pediatric Fellow" Award, OHSU Doernbecher Children's Hospital |
08/2007 - 05/2008 Clinical Research Training - selected to be one of 20 participants nationally for this mentored research program, American Society of Hematology Clinical Training Institute, Dana Point, CA |
09/2011 - 09/2013 Clinical Research Scholars Program - Selected as one of 20 clinical research scholars for a two year training program , Medical College of Wisconsin Clinical Translational and Science Institute |
05/2013 Eberhard F. Mammen Young Investigator Award, Seminars in Thrombosis and Hematostasis |
09/2014 - 05/2015 Selected to be one of 30 participants in leadership training course, MCW Leadership Academy |
2016 Department of Pediatrics Expert Clinician |
2017 - 2018 Medical College of Wisconsin Outstanding Medical Student Teacher Pin |
2017 Department of Pediatrics Expert Teacher |
2018 Department of Pediatrics Expert Teacher |
2020 Nominated Chair of the Hemostasis and Thrombosis Research Society
Mentored Research Award Committee
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MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
07/2002 - Present American Society of Hematology |
07/2002 - Present American Society of Hematology/Oncology |
10/2005 - Present American Academy of Pediatrics |
01/2006 - Present Hemophilia and Thrombosis Research Society |
01/2007 - Present International Society on Thrombosis and Haemostasis |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
01/2020 - Present Journal of Thrombosis and Haemostasis |
01/2020 - Present Blood Advances (Journal of the American Society of Hematology) |
Journal Review |
12/2006 - Present Pediatric Blood and Cancer |
12/2007 - Present Blood |
01/2008 - Present Pediatrics |
10/2009 - Present Journal of Pediatric Hematology/Oncology |
02/2010 - Present Haemophilia |
11/2010 - Present Thrombosis |
11/2010 - Present Journal of Thrombosis and Haemostasis |
04/2011 - Present International Journal of Laboratory Hematology |
08/2012 - Present Arteriosclerosis, Thrombosis, and Vascular Biology |
07/2014 - Present Circulation Research |
10/2014 - Present Translational Research |
06/2017 - Present Research and Practice in Thrombosis and Haemostasis |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
03/2004 - 12/2004 Contract Physician, Oregon State Newborn Screen Lab, Oregon Health and Science University |
07/2004 - 06/2005 Pediatric Fellowship Committee, Oregon Health and Science University |
03/2006 - 07/2006 Founding Director, Pediatric Thrombosis Clinic, OHSU Doernbecher Children's Hospital |
01/2009 - 06/2012 Hematology Rotation Director, Pediatric Hematology/Oncology Fellowship Program, Medical College of Wisconsin |
10/2009 - 12/2012 CCBD Director, Search Committee, Medical College of Wisconsin |
02/2010 - 06/2013 Participant in project to update and revitalize website, Hematology Website Redesign Committee, Medical College of Wisconsin |
07/2011 - 06/2014 Member, Women's Faculty Council, Medical College of Wisconsin |
07/2012 - 06/2013 Associate Fellowship Director, Pediatric Hematology/Oncology Fellowship Program, Medical College of Wisconsin |
07/2014 - Present Chair, Women’s Faculty Council, Medical College of Wisconsin |
09/2024 - Present Co-Chair, Search Committee, Mental and Behavioral Health In Chief, Medical College of Wisconsin |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
04/2012 - 06/2015 Member, Symposium Planning Committee, Hemostasis and Thrombosis Research Society |
04/2015 - 04/2017 Secretary, Hemostasis and Thrombosis Research Society |
01/2016 - Present Co-Chair, Von Willebrand Disease Working Group National Hemophilia Foundation |
01/2016 - 12/2020 Co-Chair, Von Willebrand Disease Scientific Subcomittee International Society on Thrombosis and Haemostasis |
10/2016 - 04/2020 Vice Chair, Mentored Research Award Review Committee Hemostasis and Thrombosis Research Society |
12/2016 - 03/2021 Planning Committee, HTRS/NASTH Joint Research Colloquium |
12/2016 - 08/2017 Planning Committee, National Hemophilia Foundation Annual Meeting |
06/2017 - 02/2018 Reviewer, NIH Study Section, National Heart, Lung, and Blood Institute, Mentored Patient-Oriented Research review panel |
07/2017 - 01/2021 Clinical Chair, American Society of Hematology VWD Guidelines |
01/2018 - 01/2022 Member, NIH Thrombosis Trials Data and Safety Monitoring Board |
08/2018 - 07/2022 Standing member, NIH Study Section, National Heart, Lung, and Blood Institute, Mentored Patient-Oriented Research review panel |
10/2019 - 07/2021 Member, Scientific Topic Theme Committee on Platelet Disorders and von Willebrand Disease, ISTH 2021 Congress Organizing Committee |
01/2020 - Present Editorial board, Blood Advances |
05/2020 - 06/2022 Chair, Mentored Research Award Review Committee, Hemostasis and Thrombosis Research Society |
07/2024 Reviewer, NIH Study Section, R35 Review Panel, National Heart, Lung, and Blood Institute |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
VWF Polymorphisms Can Sabotage the VWF:RCo Assay of VWF Function, 6th Bari International Conference, Pugnochiuso, Italy, 05/2008 |
Effect of VWF A1 Domain Sequence Variations on Type VI Collagen Binding, International Society on Thrombosis and Haemostasis XXIV Congress, 06/2013 |
Overlap of Collagen 4 and Platelet Binding Sites in VWF A1 Domain, International Society on Thrombosis and Haemostasis SSC Meeting, Poster Presentation, Milwaukee, WI, 06/2014 |
Improved Diagnosis of VWD in Affected Family Members Using the ISTH Bleeding Score, International Society on Thrombosis and Haemostasis SSC Meeting, Poster Presentation, Milwaukee, WI, 06/2014 |
Update on Collagen Assays: Zimmerman Program Analysis, International Society on Thrombosis and Haemostasis SSC Meeting, Poster Presentation, Milwaukee, WI,, 06/2014 |
Update on Bleeding Scores in the Zimmerman Program: Comparison of ISTH BAT, PBQ, and MCMDM-1VWD Scoring Systems., International Society on Thrombosis and Haemostasis SSC Meeting, Poster Presentation, Milwaukee, WI, 06/2014 |
Von Willebrand Factor Laboratory Testing, International Society of Laboratory Hematology, Chicago, IL, 05/2015 |
Abstract Symposium: Laboratory Diagnosis of Von Willebrand Disease, International Society on Thrombosis and Haemostais XXV Congress, Toronto, Canada, 06/2015 |
Low VWF Levels in Young Children, International Society on Thrombosis and Haemostasis XXVIII Congress, Milan, Italy, 07/2020 |
Update on the Laboratory Diagnosis of VWD: the ASH ISTH NHF WFH Guidelines, World Federation of Hemophilia, Montreal, Canada, 05/2022 |
Von Willebrand Disease: A Medical Overview, World Federation of Hemophilia Congress, Montreal, Canada, 05/2022 |
On the Cutting Edge: Innovations in VDW Testing, 7th Åland Islands Conference, Geta, Åland Islands, Finland, 09/2024 |
National |
Limitations of the VWF Ristocetin Cofactor Activity Assay, National Hemophilia Foundation 61st Annual Meeting, San Francisco, CA, 10/2009 |
A1 Domain Polymorphisms In Assays of VWF Function, CSL Behring VWD Leadership Advisory Board Meeting, Wilmington, DE, 10/2010 |
The VWF AI Domain: Minor Changes in Sequence, Major Changes in Function, Puget Sound Blood Center, Seattle, WA, 06/2011 |
Challenges in VWD Diagnosis, Texas Children's Hospital, Houston, TX, 09/2012 |
Von Willebrand Disease: Laboratory Testing, Thrombosis & Hemostasis Summit of North America Annual Meeting, Chicago, IL, 04/2014 |
Advances in von Willebrand Disease: Pathophysiology and Diagnosis, American Society of Pediatric Hematology/Oncology Annual Meeting, Chicago, IL, 05/2014 |
Genetic Variability of VWF: Issues in Diagnosis of VWD, Penn-CHOP Blood Center for Patient Care and Discovery, Philadelphia, PA, 07/2014 |
Phenotypic Variability in Carriers of Von Willebrand Factor Truncating Variants in the Zimmerman Program, American Society of Hematology Annual meeting, San Francisco, CA, 12/2014 |
Impact of Age and Gender on Bleeding Score in Type 1 VWD Using the ISTH-BAT, American Society of Hematology Annual meeting, Poster Presentation, San Francisco, CA, 12/2014 |
Spectrum of Type 2 von Willebrand Disease in the Zimmerman Program, American Society of Hematology Annual meeting, Oral Presentation, San Francisco, CA, 12/2014 |
New Insights into Genotype and Phenotype of von Willebrand Disease, American Society of Hematology Annual Meeting, Invited Speaker, San Francisco, CA, 12/2014 |
Diagnosis of Von Willebrand Disease: A Moving Target, Nationwide Children’s Hospital Hematology/Oncology Seminar Series, Columbus, OH, 01/2015 |
Genetic Testing in Von Willebrand Disease, Thrombosis & Hemostasis Summit of North America Annual Meeting, Chicago, IL, 10/2020 |
The 2021 Von Willebrand Disease Guidelines, Plasma Academy (for hematology fellows), Virtual, 01/2022 |
Functions of von Willebrand Factor: Collagen Binding, University of Utah Hematology Conference, Virtual, 02/2022 |
Making the Most of a Rare Bleeding Disorder, Hemophilia Federation of America Symposium, San Antonio, TX, 04/2022 |
Advances in the Diagnosis and Management of VWD, Hemophilia Federation of America Symposium, San Antonio, TX, 04/2022 |
VWD Diagnosis: A Moving Target, Brodsky Memorial Lectureship, Johns Hopkins School of Medicine, Baltimore, MD, 06/2024 |
Management Options and Prophalaxis, VWD Connect Yearly Meeting, West Palm Beach, FL, 07/2024 |
Anemia and Iron Management, VWD Connect Yearly Meeting, West Palm Beach, FL, 07/2024 |
Regional |
Von Willebrand Disease: Update on Diagnosis and Treatment, Great Lakes Hemophilia Foundation (GLHF) Fun and Education Weekend, Green Bay, WI, 06/2007 |
Common Bleeding Disorders in Pediatric Practice, Best Practices in Pediatrics, Children's Specialty Group, Egg Harbor, WI, 07/2008 |
VWF-FVIII Interactions, Hemophilia and Thrombosis Research Society Industry Summit, Chicago, IL, 09/2008 |
Von Willebrand Disease, Wheaton Franciscan Health Care-All Saints Grand Rounds, Racine, WI, 11/2008 |
Clots and Catheters, WAPHON (Wisconsin Advanced Practice Hematology Oncology Nurses) Educational Meeting, Milwaukee, WI, 09/2009 |
Menorrhagia: Workup and Treatment of Young Women with Heavy Periods, Best Practices in Pediatrics, Children’s Specialty Group, Wisconsin Dells, WI, 03/2014 |
Bleeding Disorders in Menorrhagia, Grand Rounds, St. Joseph's Hospital, West Bend, WI, 10/2014 |
Treatment for von Willebrand Disease, Great Lakes Hemophilia Foundation, Baraboo, WI, 06/2022 |
Vitamin I: Iron Deficiency in Pediatrics, Connected for Kids Pediatric Forum, Green Bay, WI, 05/2024 |
Local |
Critical Role for Collagen Binding Assays in Von Willebrand Disease Diagnosis, Blood Center of Wisconsin Hemostasis Conference, Milwaukee, WI, 02/2012 |
Diagnosis of Von Willebrand Disease: A Sticky (or not-so-sticky?) Business, Pediatric Grand Rounds, Children's Hospital of Wisconsin, Milwaukee, WI, 08/2012 |
Diagnosis of Von Willebrand Disease: A Sticky (or not-so-sticky?) Business, Children's Specialty Group Webcast, Children's Hospital of Wisconsin, Milwaukee, WI, 09/2013 |
The Expanding Role of VWF-Collagen Interactions, Children's Research Institute noon conference, Milwaukee, WI, 02/2014 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
International |
Flood VH, Al-Mondhiry HA, Farrell DH, The Fibrinogen A R16C Mutation Results in Fibrinolytic Resistance, International Society on Thrombosis and Haemostasis (ISTH) XX Congress- Oral Presentation, Sydney, Australia, 08/2005 |
Branchford BR, Kautza BC, Gill JC, Flood VH, Friedman KD, Lee A, Morateck P, Christopherson PA, Montgomery RR, Racial Disparity in the Diagnosis of von Willebrand Disease (VWD) with Particular Reference to the Diagnosis of Type 2M VWD in African Americans, Pediatric Academic Society - Poster Presentation, Toronto, Canada, 05/2007 |
Flood VH, Morateck PA, Christopherson PA, Gill JC, Friedman KD, Montgomery RR, Zimmerman Program Investigators, Functional Assays for Discrimination of Type 2 VWD Variants, International Society on Thrombosis and Haemostasis (ISTH) XXII Congress - Oral Presentation, Boston, MA, 07/2009 |
Flood VH, Haberichter SL, Friedman KD, Lentz SR, Hoffmann RG, Gill JC, Montgomery RR, Utility of von Willebrand Factor Collagen Binding Assays (VWF:CB) with Type VI Collagen in the Diagnosis of VWD, International Society on Thrombosis and Haemostasis - Poster Presentation, Kyoto, Japan, 07/2011 |
Flood VH, Haberichter SL, Friedman KD, Lentz SR, Hoffmann RG, Gill JC, Montgomery RR, Utility of von Willebrand Factor Collagen Binding Assays (VWF:CB) with Type VI Collagen in the Diagnosis of VWD, International Society on Thrombosis and Haemostasis (ISTH) XXIII Congress - Poster Presentation, Kyoto, Japan, 07/2011 |
National |
Flood VH, Johnson FL, Boshkov LK, Nugent DJ, Thomas GA, Nicholson HS, Tilford D, Godder KT, Sustained Engraftment Post Bone Marrow Transplant Despite Anti-Platelet Antibodies in Glanzmann Thrombasthenia, American Society of Pediatric Hematology/Oncology (ASPHO) Annual Meeting - Poster Presentation, San Francisco, CA, 05/2004 |
Flood VH, Al-Mondhiry HA, Farrell DH, The Paradoxical Hemorrhagic and Thrombotic Nature of the Fibrinogen A alpha R16C Mutation, American Society of Hematology (ASH) Annual Meeting - Poster Presentation, San Diego, CA, 12/2004 |
Flood VH, Al-Mondhiry HA, Bakke AC, Farrell DH, Fibrinogen Hershey IV: A Novel Dysfibrinogen with a V411I Mutation in the Integrin IIb3 Binding Site, American Society of Hematology (ASH) Annual Meeting - Poster Presentation, Atlanta, GA, 12/2005 |
Flood VH, Galderisi FC, Lowas SR, Boshkov LK, Late Hemorrhagic Disease of the Newborn in Two Patients Receiving Vitamin K at Birth: Recognition and Treatment with Recombinant Factor VIIa, Vitamin K, and Plasma, Hemophilia & Thrombosis Research Society Meeting - Poster Presentation, Chicago, IL, 04/2006 |
Flood VH, Nagaswami C, Chernysh IN, Al-Mondhiry HA, Weisel JW, Farrell DH, Effects of Impaired Fibrinopeptide A Cleavage on Fibrin Clot Structure: Studies with an A R16C Dysfibrinogen, American Society of Hematology (ASH) Annual Meeting - Poster Presentation, Orlando, FL, 12/2006 |
Bellissimo DB, Christopherson PA, Haberichter SL, Flood VH, Gill JC, Friedman KD, Abshire TC, Di Paola JA, Hoots WK, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Montgomery RR, Novel VWF Sequence Variations Identified in Normal Controls and Index Cases Enrolled in the TS Zimmerman Program for the Molecular and Clinical Biology of VWD (ZPMCB-VWD), American Society of Hematology (ASH) Annual Meeting - Oral Presentation, Atlanta, GA, 12/2007 |
Montgomery RR, Morateck P, Christopherson PA, Kautza BC, Miller CA, Branchford BR, Flood VH, Haberichter SL, Bellissimo DB, Friedman KD, Kenny DJ, Gill JC, Functional Assay of VWF Measured by its Interaction with Platelet GPIb without the Use of Ristocetin, American Society of Hematology (ASH) Annual Meeting - Oral Presentation, Atlanta, GA, 12/2007 |
Flood VH, Kautza BC, Miller CA, Branchford BR, Gill JC, Haberichter SL, Morateck PA, Christopherson PA, Perry CL, Friedman KD, Bellissimo DB, Abshire TC, Di Paola JA, Hoots WK, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Lillicrap D, Goodeve AC, Peake IR, Montgomery RR, Common VWF Haplotypes in Normal African-Americans and Caucasians Recruited into the ZPMCB-VWD and Their Impact on VWF Laboratory Testing, American Society of Hematology (ASH) Annual Meeting - Oral Presentation, Atlanta, GA, 12/2007 |
Flood VH, Kautza BC, Miller CA, Branchford BR, Gill JC, Haberichter SL, Morateck PA, Christopherson PA, Perry CL, Friedman KD, Bellissimo DB, Abshire TC, Lusher JM, Hoots WK, Shapiro AD, Di Paola JA, Leissinger C, Ragni MV, Lillicrap D, Goodeve AC, Peake IR, Montgomery RR, The Impact of Common VWF Polymorphisms in African Americans and Caucasians on Laboratory Tests of VWF Function, Gordon Research Conference on Hemostasis - Poster Presentation, Waterville Valley, NH, 07/2008 |
Gill JC, Christopherson PA, Flood VH, Friedman KD, Montgomery RR, Zimmerman Program Investigators, Bleeding Scores in von Willebrand Disease (VWD) Re-visited: Analysis of the TS Zimmerman Program for the Molecular and Clinical Biology of VWD, American Society of Hematology (ASH) Annual Meeting - Oral Presentation, San Francisco, CA, 12/2008 |
Flood VH, Morateck PA, Christopherson PA, Friedman KD, Gill JC, Montgomery RR, Zimmerman Program Investigators, Unique ELISA-Based Assays for VWF-GPIb Interactions and the Impact of Racial Differences on VWF Testing, American Society of Hematology (ASH) Annual Meeting - Oral Presentation, San Francisco, CA, 12/2008 |
Flood VH, Lederman CA, Wren JS, Christopherson PA, Friedman KD, Montgomery RR, A Novel VWF A3 Domain Mutation with Absent Binding to Type I and Type III Collagen, American Society of Hematology (ASH) Annual Meeting - Oral Presentation, New Orleans, LA, 12/2009 |
Flood VH, Lederman CA, Wren JS, Christopherson PA, Friedman KD, Montgomery RR, Absent Collagen Binding in a VWF A3 Domain Mutant: Utility of the VWF:CB in Diagnosis of VWD, Gordon Research Conference on Hemostasis - Poster Presentation, Waterville Valley, NH, 07/2010 |
Flood VH, Haberichter SL, Friedman KD, Lentz SR, Gill JC, Montgomery RR, VWF Binding to Types I, III, or VI Collagen in the ZPMCB-VWD with Identification of Subjects with Selective Reduced Plasma VWF:CB, American Society of Hematology (ASH) Annual Meeting - Oral Presentation, Orlando, FL, 12/2010 |
Flood VH, Wren JS, Haberichter SL, Friedman KD, Bellissimo DB, Gill JC, Hoffmann RG, Scott JP, Montgomery RR, Low VWF:RCo in Subjects with VWF Polymorphisms P1472H and P1467S Due to Decreased Binding of Ristocetin to the VWF A1 Domain, American Society of Hematology (ASH) Annual Meeting - Poster Presentation, Orlando, FL, 12/2010 |
Friedman KD, Bellissimo, D.B., Christopherson PA, Flood VH, Gill JC, Montgomery RR, Haberichter SL, Fourteen Percent of Healthy African Americans Participating in the Zimmerman Program for the Molecular and Clinical Biology of VWD (ZPMCB-VWD) are Heterozygous for the VWF Gene Mutation H817Q Associa, American Society of Hematology (ASH) Annual Meeting - Oral Presentation, Orlando, FL, 12/2010 |
Haberichter SL, Jacobi PM, Flood VH, Christopherson PA, Gill JC, Bellissimo DB, Friedman KD, Zimmerman Program Investigators, Quantitative Analysis of VWF Multimer Structure: Discrimination Between VWD Subtypes, American Society of Hematology (ASH) Annual Meeting - Poster Presentation, San Diego, CA, 12/2011 |
Montgomery RR, Christopherson PA, Haberichter SL, Flood VH, Gill JC, Zimmerman Program Investigators, Diagnostic Fidelity of Historically Diagnosed Patients with VWD Enrolled from 27 Centers in the ZPMCB-VWD, American Society of Hematology (ASH) Annual Meeting - Poster Presentation, San Diego, CA, 12/2011 |
Flood VH, Gill JC, Friedman KD, Christopherson PA, Jacobi PM, Montgomery RR, Haberichter SL, Von Willebrand Factor Collagen Binding Provides a Sensitive Screen for Identification of Type 2A and 2B Von Willebrand Disease, American Society of Hematology (ASH) Annual Meeting - Poster Presentation, San Diego, CA, 12/2011 |
Local |
Flood VH, Anemia and Jaundice in a Two Year Old Boy, Mayo Clinic Scottsdale Academic Excellence Day - Poster Presentation, Scottsdale, AZ, 05/2001 |
Flood VH, The Case of the Swollen Knee, Mayo Clinic Scottsdale Academic Excellence Day - Poster Presentation, Scottsdale, AZ, 05/2002 |
Sheppard A, Flood VH, Characterization of Variant Fibrinogens, Northwest Undergraduate Science Research Conference - Oral Presentation, Portland, OR, 04/2005 |
Flood VH, The Fibrinogen A(alpha)R16C Mutation Results in Fibrinolytic Resistance, OHSU Heart Research Center Retreat, Portland, OR, 10/2005 |
Johnson C, Flood VH, Characterization of Acquired Dysfibrinogenemia in Liver Cirrhosis, Northwest Undergraduate Science Research Conference - Oral Presentation, Portland, OR, 04/2006 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
01/2008 - 06/2013 Member, Fellowship Selection Committee, Hematology/Oncology/BMT, Pediatrics, Medical College of Wisconsin |
09/2009 Poster Reviewer, Medical Student Research Day, Medical College of Wisconsin |
02/2010 - Present Member, Website Redesign Committee, Hematology, Pediatrics, Medical College of Wisconsin |
07/2011 - Present Member, Women's Faculty Council, Medical College of Wisconsin |
08/2011 - 06/2014 Liaison from Women's Faculty Council, Faculty Career Development Committee, Medical College of Wisconsin |
10/2011 Poster Reviewer, Graduate School Research Day, Hematology, Pediatrics, Medical College of Wisconsin |
2011 - Present Co-Chair, Clinical Integration Committee, Pediatrics, Medical College of Wisconsin |
07/2012 - 06/2013 Representative from Faculty Career Development Committee, Discovery Curriculum Faculty Development Workgroup, Hematology, Pediatrics, Medical College of Wisconsin |
05/2013 - 08/2013 Member, Faculty Scholarly Evaluation Committee, Pediatrics, Medical College of Wisconsin |
2014 - 2015 Chair, Women's Faculty Council, Medical College of Wisconsin |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
01/2007 - Present Oversee 3rd and 4th year medical students covering hematology patients on the inpatient hematology service (initially four weeks per year, increased to six weeks per year in 2009) |
08/2010 - Present Review H&Ps for 3rd year medical students on their pediatric rotation (approximately 4 hours per month, 4 months per year) |
03/2011 - Present Assisting in developing module for coagulation teaching as part of coagulation curriculum for second year medical students as part of the new curriculum |
01/2012 - Present Teaching coagulation module as part of coagulation curriculum for second year medical students |
Resident and Fellow Education |
01/2007 - Present Oversee 1st year residents covering hematology patients on the inpatient hematology service (initially four weeks per year, increased to six weeks per year in 2009) |
01/2007 - Present Oversee residents in hematology clinic during their outpatient hematology rotation elective (12 hours per month) |
01/2007 - Present Supervise fellows in hematology clinic, on inpatient service, and during weekend call, including: General hematology clinic, Coagulation clinic, Hematology inpatient service six weeks per year |
09/2007 - Present Fellowship curriculum lectures: Congenital and Acquired Anemia; Nutritional Anemias; Qualitative Disorders of Neutrophils; Quantitative Disorders of Neutrophils |
09/2010 Ace the Boards Pediatric Board Review Course, Hematology for the Pediatric Board Review, Lecture for review course intended for pediatric residents |
01/2011 Core curriculum lecture for residents on coagulation disorders, Inherited and Acquired Bleeding Disorders: Coagulation Factors |
02/2011 Core curriculum lecture for residents on platelet disorders, Inherited and Acquired Bleeding Disorders: Platelets |
Continuing Medical Education |
03/2008 Children's Research Institute Academic Conference Presentation - Common VWF Polymorphisms and Their Effect on Assays of VWF Function |
09/2008 Team Conference, Child Advocacy Center Presentation - Common Bleeding Disorders and Child Abuse |
02/2010 Hematology/Oncology Nursing Conference Presentation - Pediatric Bleeding Disorders |
02/2011 Children's Research Institute Academic Conference Presentation - Clinical Implications of VWF A1 Domain Polymorphisms |
05/2011 Pediatric Hematology/Oncology Conference Presentation - The Importance of VWF-Collagen Interactions |
EXTRAMURAL TEACHING: |
Medical Student Education |
04/2005 - 04/2006 Oregon Health & Science University, Biological Basis of Disease, small group leader, Coagulation Disorders, Transfusion Medicine, Red Cell Disorders, Inherited Thrombotic Disorders |
03/2006 Oregon Health & Science University, Biological Basis of Disease, lecturer, Inherited Bleeding Disorders |
Resident and Fellow Education |
01/2003 Oregon Health & Science University, Doernbecher Children's Hospital Grand Rounds, Lymphomatoid Granulomatosis |
01/2006 Oregon Health & Science University, Doernbecher Children's Hospital Grand Rounds, Update on Management of Pediatric Deep Venous Thrombosis |
Continuing Medical Education |
11/2003 Oregon Health & Science University, Doernbecher Children's Hospital Nursing Education Day Presentation - Immune Thrombocytopenic Purpura Portland, OR |
11/2004 Oregon Health & Science University, Doernbecher Children's Hospital Nursing Education Day Presentation - Pediatric Anemia |
01/2006 Oregon Hematology Update Conference, ASH Update: Hemostasis |
03/2006 Oregon Health & Science University, Physician Assistant Student Education Presentation - Inherited Bleeding Disorders |
07/2008 Children’s Specialty Group, Best Practices in Pediatrics Presentation - Common Bleeding Disorders in Pediatric Practice |
Community/Lay Public |
01/2006 Oregon Health & Science University, Oregon Hematology Update Conference, ASH Update: Hemostasis |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Undergraduate Students |
05/2011 - 08/2011 Dana Larsen, laboratory mentor for summer project on VWD, Medical College of Wisconsin |
Medical Students |
05/2007 - 11/2008 Benjamin Kautza, Laboratory mentor during his rotations with Dr. Montgomery, Medical College of Wisconsin |
11/2010 - 06/2012 Rachel martin, Mentor during her pediatric clerkship and her search for a pediatric residency program, Medical College of Wisconsin |
01/2011 - Present Amanda Martin, Pathway Advisor starting in first year of medical school, Medical College of Wisconsin |
11/2012 - Present Abraham Schlauderaff, Pathway Advisor and Research Mentor, Medical College of Wisconsin |
Clinical/Research Fellows |
11/2009 - Present Dr. Hema Rangarajan, Scholarship Oversight Committee, Medical College of Wisconsin |
02/2010 Dr. Samip Kothari, Mentor for Physiology Conference talk on neonatal hemostasis, Medical College of Wisconsin |
01/2012 - 06/2014 Jonathan Roberts, Scholarship Oversight Committee, Medical College of Wisconsin |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Undergraduate Students |
05/2004 - 04/2005 Amara Sheppard, Project Mentor, Oregon Health & Science University |
05/2005 - 04/2006 Cassie Johnson, Project Mentor, Oregon Health & Science University |
PROGRAMMATIC DEVELOPMENTS: |
Educational Programs |
Student |
2011 - Present Medical College of Wisconsin Medical School New I Discovery Curriculum |
Fellow |
2009 - 2012 Hematology Rotation Director, Pediatric Hematology/Oncology Fellowship Programy |
2009 - 2012 Assist with Journal Club, Research, Clinical and Professional Mentoring |
2012 Associate Fellowship Director, Pediatric Hematology /Oncology |
Clinical Programs |
2006 Founding director of pediatric thrombosis clinic providing followup monitoring, care, and anticoagulation management for all patients who experienced thrombosis |
2012 - Present Started Combined Hematology/Adolescent Medicine/Gynecology Menorrhagia Clinic |
COMMUNITY SERVICE ACTIVITIES: |
08/2003 - 08/2004 Camp physician, Camp Tapawingo, Falls City, OR |
01/2008 - Present Alumni Interviewer for Harvard College |
MEDIA DEVELOPMENT: |
02/2012 - 09/2012 Developed iPad and mobile device application for Von Willebrand Disease quick guide for clinicians for the American Society of Hematology |
PROGRAMMATIC DEVELOPMENT - NATIONAL: |
02/2012 - 09/2012 American Society of Hematology - Developed content and format for a mobile device compatible quick guide to von Willebrand disease, titled "VWD Pocket Guide" available as a free download from the American Society of Hematology |
2012 - Present Co-Chair of Planning Committee for 2015 Symposium |
2012 - Present Hemostasis and Thrombosis Research Society Planning Committee for 2013 Symposium |
RESEARCH EDUCATION: |
03/2008 "Common VWF Polymorphisms and Their Effect on Assays of VWF Function", Children's Research Institute Academic Conference |
09/2008 “Common Bleeding Disorders and Child Abuse” Team Conference, Child Advocacy Center |
02/2010 "Pediatric Bleeding Disorders" Hematology/Oncology Nursing Conference |
02/2011 “Clinical Implications of VWF AI Domain Polymorphisms”, Children's Research Institute Academic Conference |
05/2011 “The Importance of VWF-Collagen Interactions”, Pediatric Hematology/Oncology Conference |
02/2012 “Implications of Collagen Binding in VWD Diagnosis”, Clinical and Translational Science Institute Research Seminar |
02/2014 “The Expanding Role of VWF-Collagen Interactions”, Children's Research Institute Academic Conference |
10/2024 "The Index Case: von Willebrand Disease", Children's Research Institute Academic Conference |
10/2024 "What We Have Learned About VWF and VWD: Contributions of the Zimmerman Program", Montgomery Educational Symposium on Hemostasis |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Flood VH, Johnson FL, Boshkov LK, Thomas GA, Nugent DJ, Bakke AC, Nicholson HS, Tilford D, Brown MP, Godder KT. Sustained engraftment post bone marrow transplant despite anti-platelet antibodies in Glanzmann thrombasthenia. Pediatr Blood Cancer. 2005 Dec;45(7):971-5. |
2. Flood VH, Al-Mondhiry HA, Farrell DH. The fibrinogen Aalpha R16C mutation results in fibrinolytic resistance. Br J Haematol. 2006 Jul;134(2):220-6. |
3. Flood VH, Nagaswami C, Chernysh IN, Al-Mondhiry HA, Weisel JW, Farrell DH. Incorporation of fibrin molecules containing fibrinopeptide A alters clot ultrastructure and decreases permeability. Br J Haematol. 2007 Jul;138(1):117-24. |
4. Flood VH, Galderisi FC, Lowas SR, Kendrick A, Boshkov LK. Hemorrhagic disease of the newborn despite vitamin K prophylaxis at birth. Pediatr Blood Cancer. 2008 May;50(5):1075-7. |
5. Flood VH, Al-Mondhiry HA, Rein CM, Alexander KS, Lovely RS, Shackleton KM, David LL, Farrell DH. Fibrinogen Hershey IV: a novel dysfibrinogen with a gammaV411I mutation in the integrin alpha(IIb)beta(3) binding site. Thromb Haemost. 2008 Jun;99(6):1008-12. PMCID: PMC4089099 |
6. Flood VH, Friedman KD, Gill JC, Morateck PA, Wren JS, Scott JP, Montgomery RR. Limitations of the ristocetin cofactor assay in measurement of von Willebrand factor function. J Thromb Haemost. 2009 Nov;7(11):1832-9. PMCID: PMC3825106 |
7. Flood VH, Lederman CA, Wren JS, Christopherson PA, Friedman KD, Hoffmann RG, Montgomery RR. Absent collagen binding in a VWF A3 domain mutant: utility of the VWF:CB in diagnosis of VWD. J Thromb Haemost. 2010 Jun;8(6):1431-3. PMCID: PMC3892206 |
8. Flood VH, Gill JC, Morateck PA, Christopherson PA, Friedman KD, Haberichter SL, Branchford BR, Hoffmann RG, Abshire TC, Di Paola JA, Hoots WK, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Montgomery RR. Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor. Blood. 2010 Jul 15;116(2):280-6. PMCID: PMC2910611 |
9. Flood VH, Gill JC, Morateck PA, Christopherson PA, Friedman KD, Haberichter SL, Hoffmann RG, Montgomery RR. Gain-of-function GPIb ELISA assay for VWF activity in the Zimmerman Program for the Molecular and Clinical Biology of VWD. Blood. 2011 Feb 10;117(6):e67-74. PMCID: PMC3056647 |
10. Flood VH, Gill JC, Friedman KD, Bellissimo DB, Haberichter SL, Montgomery RR. Von Willebrand disease in the United States: a perspective from Wisconsin. Semin Thromb Hemost. 2011 Jul;37(5):528-34. PMCID: PMC3807766 |
11. Bellissimo DB, Christopherson PA, Flood VH, Gill JC, Friedman KD, Haberichter SL, Shapiro AD, Abshire TC, Leissinger C, Hoots WK, Lusher JM, Ragni MV, Montgomery RR. VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population. Blood. 2012 Mar 01;119(9):2135-40. PMCID: PMC3311248 |
12. Jacobi PM, Gill JC, Flood VH, Jakab DA, Friedman KD, Haberichter SL. Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage. Blood. 2012 May 10;119(19):4543-53. PMCID: PMC3362367 |
13. Flood VH, Gill JC, Christopherson PA, Bellissimo DB, Friedman KD, Haberichter SL, Lentz SR, Montgomery RR. Critical von Willebrand factor A1 domain residues influence type VI collagen binding. J Thromb Haemost. 2012 Jul;10(7):1417-24. PMCID: PMC3809952 |
14. Flood VH, Gill JC, Christopherson PA, Wren JS, Friedman KD, Haberichter SL, Hoffmann RG, Montgomery RR. Comparison of type I, type III and type VI collagen binding assays in diagnosis of von Willebrand disease. J Thromb Haemost. 2012 Jul;10(7):1425-32. PMCID: PMC3809762 |
15. Franzblau EB, Punzalan RC, Friedman KD, Roy A, Bilen O, Flood VH. Use of purified fibrinogen concentrate for dysfibrinogenemia and importance of laboratory fibrinogen activity measurement. Pediatr Blood Cancer. 2013 Mar;60(3):500-2. PMCID: PMC4461026 |
16. Flood VH, Gill JC, Friedman KD, Christopherson PA, Jacobi PM, Hoffmann RG, Montgomery RR, Haberichter SL, Zimmerman Program Investigators. Collagen binding provides a sensitive screen for variant von Willebrand disease. Clin Chem. 2013 Apr;59(4):684-91. PMCID: PMC3852672 |
17. Larsen DM, Haberichter SL, Gill JC, Shapiro AD, Flood VH. Variability in platelet- and collagen-binding defects in type 2M von Willebrand disease. Haemophilia. 2013 Jul;19(4):590-4. PMCID: PMC3688679 |
18. Flood VH, Friedman KD, Gill JC, Haberichter SL, Christopherson PA, Branchford BR, Hoffmann RG, Abshire TC, Dunn AL, Di Paola JA, Hoots WK, Brown DL, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Montgomery RR. No increase in bleeding identified in type 1 VWD subjects with D1472H sequence variation. Blood. 2013 May 02;121(18):3742-4. PMCID: PMC3643771 |
19. Dobrozsi S, Flood VH, Panepinto J, Scott JP, Brandow A. Vitamin B12 deficiency: the great masquerader. Pediatr Blood Cancer. 2014 Apr;61(4):753-5. |
20. Flood VH. Perils, problems, and progress in laboratory diagnosis of von Willebrand disease. Semin Thromb Hemost. 2014 Feb;40(1):41-8. PMCID: PMC3987108 |
21. Flood VH, Schlauderaff AC, Haberichter SL, Slobodianuk TL, Jacobi PM, Bellissimo DB, Christopherson PA, Friedman KD, Gill JC, Hoffmann RG, Montgomery RR, Zimmerman Program Investigators. Crucial role for the VWF A1 domain in binding to type IV collagen. Blood. 2015 Apr 02;125(14):2297-304. PMCID: PMC4383803 |
22. Flood VH. New insights into genotype and phenotype of VWD. Hematology Am Soc Hematol Educ Program. 2014 Dec 05;2014(1):531-5. PMCID: PMC4696506 |
23. Chen J, Hinckley JD, Haberichter S, Jacobi P, Montgomery R, Flood VH, Wong R, Interlandi G, Chung DW, López JA, Di Paola J. Variable content of von Willebrand factor mutant monomer drives the phenotypic variability in a family with von Willebrand disease. Blood. 2015 Jul 09;126(2):262-9. PMCID: PMC4497966 |
24. Roberts JC, Flood VH. Laboratory diagnosis of von Willebrand disease. Int J Lab Hematol. 2015 May;37 Suppl 1(Suppl 1):11-7. PMCID: PMC5600156 |
25. Flood VH. Platelet-derived VWF in the stroke spotlight. Blood. 2015 Oct 01;126(14):1640-1. PMCID: PMC4591789 |
26. Cooper S, Sell S, Nelson L, Hawes J, Benrud JA, Kohlnhofer BM, Burmeister BR, Flood VH. Von Willebrand factor is reversibly decreased during torpor in 13-lined ground squirrels. J Comp Physiol B. 2016 Jan;186(1):131-9. PMCID: PMC4838567 |
27. Cooper S, Sell S, Nelson L, Hawes J, Benrud JA, Kohlnhofer BM, Burmeister BR, Flood VH. Von Willebrand factor is reversibly decreased during torpor in 13-lined ground squirrels. J Comp Physiol B. 2016 Jan;186(1):131-9. PMCID: PMC4838567 |
28. Flood VH, Christopherson PA, Gill JC, Friedman KD, Haberichter SL, Bellissimo DB, Udani RA, Dasgupta M, Hoffmann RG, Ragni MV, Shapiro AD, Lusher JM, Lentz SR, Abshire TC, Leissinger C, Hoots WK, Manco-Johnson MJ, Gruppo RA, Boggio LN, Montgomery KT, Goodeve AC, James PD, Lillicrap D, Peake IR, Montgomery RR. Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States. Blood. 2016 May 19;127(20):2481-8. PMCID: PMC4874228 |
29. Montgomery RR, Flood VH. What have we learned from large population studies of von Willebrand disease? Hematology Am Soc Hematol Educ Program. 2016 Dec 02;2016(1):670-677. PMCID: PMC5518316 |
30. Doruelo AL, Haberichter SL, Christopherson PA, Boggio LN, Gupta S, Lentz SR, Shapiro AD, Montgomery RR, Flood VH. Clinical and laboratory phenotype variability in type 2M von Willebrand disease. J Thromb Haemost. 2017 Aug;15(8):1559-1566. PMCID: PMC5538962 |
31. Sharma R, Flood VH. Advances in the diagnosis and treatment of Von Willebrand disease. Blood. 2017 Nov 30;130(22):2386-2391. PMCID: PMC5709787 |
32. Sharma R, Flood VH. Advances in the diagnosis and treatment of Von Willebrand disease. Hematology Am Soc Hematol Educ Program. 2017 Dec 08;2017(1):379-384. PMCID: PMC6142610 |
33. Alaqzam TS, Stanley AC, Simpson PM, Flood VH, Menon S. Treatment Modalities in Adolescents Who Present with Heavy Menstrual Bleeding. J Pediatr Adolesc Gynecol. 2018 Oct;31(5):451-458. |
34. Keesler DA, Flood VH. Current issues in diagnosis and treatment of von Willebrand disease. Res Pract Thromb Haemost. 2018 Jan;2(1):34-41. PMCID: PMC5974913 |
35. Flood VH, Johnsen JM, Kochelek C, Slobodianuk TL, Christopherson PA, Haberichter SL, Udani R, Bellissimo DB, Friedman KD, Montgomery RR. Common <i>VWF</i> sequence variants associated with higher VWF and FVIII are less frequent in subjects diagnosed with type 1 VWD. Res Pract Thromb Haemost. 2018 Apr;2(2):390-398. PMCID: PMC5974909 |
36. Flood VH, Abshire TC, Christopherson PA, Friedman KD, Cox Gill J, Montgomery RR, Haberichter SL, Zimmerman Program Investigators. Von Willebrand disease in the United States: perspective from the Zimmerman program. Ann Blood. 2018 Jan;3. PMCID: PMC6100783 |
37. Slobodianuk TL, Kochelek C, Foeckler J, Kalloway S, Weiler H, Flood VH. Defective collagen binding and increased bleeding in a murine model of von Willebrand disease affecting collagen IV binding. J Thromb Haemost. 2019 Jan;17(1):63-71. PMCID: PMC6743498 |
38. Flood VH, Garcia J, Haberichter SL. The role of genetics in the pathogenesis and diagnosis of type 1 Von Willebrand disease. Curr Opin Hematol. 2019 Sep;26(5):331-335. PMCID: PMC6727843 |
39. Wang M, Konkle BA, Sidonio RF Jr, Flood V, Koenig C, Kulkarni R. von Willebrand disease Outreach into Integrated Care Education (VOICE): a call to action. Haemophilia. 2017 Jul;23(4):e370-e373. |
40. Flood VH, Scott JP. Bleeding and Thrombosis Nelson Pediatric Symptom-Based Diagnosis. 24 April 2017:682-701. |
41. Berntorp E, Fuchs B, Makris M, Montgomery R, Flood V, O'Donnell JS, Federici AB, Lillicrap D, James P, Budde U, Morfini M, Petrini P, Austin S, Kannicht C, Jiménez-Yuste V, Lee C. Third Åland islands conference on von Willebrand disease, 26-28 September 2012: meeting report. Haemophilia. 2013 Mar;19 Suppl 3(0 3):1-18. PMCID: PMC4164969 |
42. Flood VH, Montgomery RR. von Willebrand Disease: Biologic Diagnosis Textbook of Hemophilia: Second Edition. 13 August 2010:294-301. |
43. Weyand AC, Flood VH, Shavit JA, Pipe SW. Efficacy of emicizumab in a pediatric patient with type 3 von Willebrand disease and alloantibodies. Blood Adv. 2019 Sep 24;3(18):2748-2750. PMCID: PMC6759735 |
44. Kalot MA, Al-Khatib M, Connell NT, Flood V, Brignardello-Petersen R, James P, Mustafa RA, VWD working group. An international survey to inform priorities for new guidelines on von Willebrand disease. Haemophilia. 2020 Jan;26(1):106-116. PMCID: PMC7041556 |
45. Gill JC, Conley SF, Johnson VP, Christopherson PA, Haberichter SL, Diaz CD, Strong TC, Zhang J, Simpson P, Abshire TC, Montgomery RR, Flood VH. Low VWF levels in children and lack of association with bleeding in children undergoing tonsillectomy. Blood Adv. 2020 Jan 14;4(1):100-105. PMCID: PMC6960478 |
46. Garcia J, Flood VH, Haberichter SL, Fahs SA, Mattson JG, Geurts AM, Zogg M, Weiler H, Shi Q, Montgomery RR. A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9. Res Pract Thromb Haemost. 2020 Jan;4(1):64-71. PMCID: PMC6971331 |
47. Flood VH, Slobodianuk TL, Keesler D, Lohmeier HK, Fahs S, Zhang L, Simpson P, Montgomery RR. von Willebrand factor binding to myosin assists in coagulation. Blood Adv. 2020 Jan 14;4(1):174-180. PMCID: PMC6960459 |
48. Lohmeier HK, Slobodianuk TL, Kanaji S, Haberichter SL, Montgomery RR, Flood VH. von Willebrand factor variant D1472H has no effect in mice with humanized VWF-platelet interactions. Blood Adv. 2020 Sep 08;4(17):4065-4068. PMCID: PMC7479953 |
49. DiGiandomenico S, Christopherson PA, Haberichter SL, Abshire TC, Montgomery RR, Flood VH, Zimmerman Program Investigators. Laboratory variability in the diagnosis of type 2 VWD variants. J Thromb Haemost. 2021 Jan;19(1):131-138. PMCID: PMC7790985 |
50. Flood, V.H., Slobodianuk, T.L., Keesler, D., Lohmeier, H.K., Fahs, S., Zhang, L., Simpson, P., Montgomery, R.R. Von Willebrand Factor Binding to Myosin Assists in Coagulation. Blood Advances 4(1):174-180, 2020. |
51. *Kalot, M.A., Al-Khatib, M., Connell, N.T., Flood, V., Brignardello-Petersen, R., James, P., Mustafa, R.A., and the VWD Working Group. An International Survey to Inform Priorities for new Guidelines on von Willebrand Disease. Haemophilia 26(1):106-116, 2020. |
52. *Lohmeier, H.K., Slobodianuk, T.L., Kanaji, S., Haberichter, S.L., Montgomery, R.R., Flood, V.H. Von Willebrand Factor Variant D1472H Has No Effect in Mice with Humanized VWF-Platelet Interactions. Blood Advances 4(7):4065-4068, 2020. |
53. *DiGiandomenico, S., Christopherson, P.A., Haberichter, S.L., Abshire, T.C., Montgomery, R.R., Flood, V.H. and the Zimmerman Program Investigators. Laboratory Variability in the Diagnosis of Type 2 Von Willebrand Disease Variants. J Thromb Haemost 2020 in press. |
54. Connell NT, James PD, Brignardello-Petersen R, Abdul-Kadir R, Ameer B, Arapshian A, Couper S, Di Paola J, Eikenboom J, Giraud N, Grow JM, Haberichter S, Jacobs-Pratt V, Konkle BA, Kouides P, Laffan M, Lavin M, Leebeek FWG, McLintock C, McRae S, Montgomery R, O'Brien SH, O'Donnell JS, Ozelo MC, Scappe N, Sidonio R, Tosetto A, Weyand AC, Kalot MA, Husainat N, Mustafa RA, Flood VH. von Willebrand disease: proposing definitions for future research. Blood Adv. 2021 Jan 26;5(2):565-569. PMCID: PMC7839375 |
55. Connell NT, Flood VH, Brignardello-Petersen R, Abdul-Kadir R, Arapshian A, Couper S, Grow JM, Kouides P, Laffan M, Lavin M, Leebeek FWG, O'Brien SH, Ozelo MC, Tosetto A, Weyand AC, James PD, Kalot MA, Husainat N, Mustafa RA. ASH ISTH NHF WFH 2021 guidelines on the management of von Willebrand disease. Blood Adv. 2021 Jan 12;5(1):301-325. PMCID: PMC7805326 |
56. James PD, Connell NT, Ameer B, Di Paola J, Eikenboom J, Giraud N, Haberichter S, Jacobs-Pratt V, Konkle B, McLintock C, McRae S, R Montgomery R, O'Donnell JS, Scappe N, Sidonio R, Flood VH, Husainat N, Kalot MA, Mustafa RA. ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease. Blood Adv. 2021 Jan 12;5(1):280-300. PMCID: PMC7805340 |
57. James PD, Connell NT, Ameer B, Di Paola J, Eikenboom J, Giraud N, Haberichter S, Jacobs-Pratt V, Konkle B, McLintock C, McRae S, Montgomery RR, O'Donnell JS, Scappe N, Sidonio R, Flood VH, Husainat N, Kalot MA, Mustafa RA. ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease Blood Advances. 2021;5(1):280-300. |
58. Keesler DA, Slobodianuk TL, Kochelek CE, Skaer CW, Haberichter SL, Flood VH. Fibronectin binding to von Willebrand factor occurs via the A1 domain. Res Pract Thromb Haemost. 2021 Jun;5(5):e12534. PMCID: PMC8178691 |
59. Weyand AC, Flood VH. Von Willebrand Disease: Current Status of Diagnosis and Management. Hematol Oncol Clin North Am. 2021 Dec;35(6):1085-1101. PMCID: PMC8919990 |
60. Kalot MA, Husainat N, Tayiem S, El Alayli A, Dimassi AB, Diab O, Abughanimeh O, Madoukh B, Qureini A, Ameer B, Di Paola J, Eikenboom JCJ, Jacobs-Pratt V, McLintock C, Montgomery R, O'Donnell JS, Sidonio R, Brignardello-Petersen R, Flood V, Connell NT, James PD, Mustafa RA. Bleeding assessment tools in the diagnosis of VWD in adults and children: a systematic review and meta-analysis of test accuracy. Blood Adv. 2021 Dec 14;5(23):5023-5031. PMCID: PMC9153010 |
61. Digiandomenico S, Conley SF, Johnson VP, Christopherson PA, Haberichter SL, Zhang J, Simpson P, Abshire TC, Montgomery RR, Flood VH. Screening for von Willebrand disease does not impact posttonsillectomy bleeding in a low-risk population. Pediatr Blood Cancer. 2021 Dec;68(12):e29371. PMCID: PMC8919995 |
62. Brignardello-Petersen R, El Alayli A, Husainat N, Kalot M, Shahid S, Aljabirii Y, Britt A, Alturkmani H, El-Khechen H, Motaghi S, Roller J, Dimassi A, Abughanimeh O, Madoukh B, Arapshian A, Grow JM, Kouides P, Laffan M, Leebeek FWG, O'Brien SH, Tosetto A, James PD, Connell NT, Flood V, Mustafa RA. Surgical management of patients with von Willebrand disease: summary of 2 systematic reviews of the literature. Blood Adv. 2022 Jan 11;6(1):121-128. PMCID: PMC8753200 |
63. Kalot MA, Husainat N, El Alayli A, Abughanimeh O, Diab O, Tayiem S, Madoukh B, Dimassi AB, Qureini A, Ameer B, Eikenboom JCJ, Giraud N, McLintock C, McRae S, Montgomery RR, O'Donnell JS, Scappe N, Sidonio RF, Brignardello-Petersen R, Flood VH, Connell NT, James PD, Mustafa RA. von Willebrand factor levels in the diagnosis of von Willebrand disease: a systematic review and meta-analysis. Blood Adv. 2022 Jan 11;6(1):62-71. PMCID: PMC8753202 |
64. Brignardello-Petersen R, El Alayli A, Husainat N, Kalot MA, Shahid S, Aljabirii Y, Britt A, Alturkmani H, El-Khechen H, Motaghi S, Roller J, Abdul-Kadir R, Couper S, Kouides P, Lavin M, Ozelo MC, Weyand A, James PD, Connell NT, Flood VH, Mustafa RA. Gynecologic and obstetric management of women with von Willebrand disease: summary of 3 systematic reviews of the literature. Blood Adv. 2022 Jan 11;6(1):228-237. PMCID: PMC8753192 |
65. Kalot MA, Husainat N, Abughanimeh O, Diab O, El Alayli A, Tayiem S, Madoukh B, Dimassi A, Qureini A, Ameer B, Eikenboom J, Giraud N, Haberichter S, Jacobs-Pratt V, Konkle BA, McRae S, Montgomery R, O'Donnell JS, Brignardello-Petersen R, Flood V, Connell NT, James P, Mustafa RA. Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis. Blood Adv. 2022 Jun 28;6(12):3735-3745. PMCID: PMC9631556 |
66. Valentino LA, Hardy ML, James P, Connell NT, Flood V, Scappe N, Frick N. von Willebrand disease (VWD) and BATs: How do they connect and why should I care? Haemophilia. 28(3):e89-e90. 2022 |
67. James PD, Connell NT, Flood VH, Mustafa RA. Response to "The 2021 von Willebrand disease guidelines: Clarity and controversy". Haemophilia. 2022 May;28(3):371-372. |
68. El Alayli A, Brignardello Petersen R, Husainat NM, Kalot MA, Aljabiri Y, Turkmani H, Britt A, El-Khechen H, Shahid S, Roller J, Motaghi S, Mansour R, Tosetto A, Abdul-Kadir R, Laffan M, Weyand A, Leebeek FWG, Arapshian A, Kouides P, James P, Connell NT, Flood VH, Mustafa RA. Outcomes of long-term von Willebrand factor prophylaxis use in von Willebrand disease: A systematic literature review. Haemophilia. 2022 May;28(3):373-387. |
69. Christopherson PA, Haberichter SL, Flood VH, Perry CL, Sadler BE, Bellissimo DB, Di Paola J, Montgomery RR, Zimmerman Program Investigators. Molecular pathogenesis and heterogeneity in type 3 VWD families in U.S. Zimmerman program. J Thromb Haemost. 2022 Jul;20(7):1576-1588. |
70. Lavin, M., Christopherson, P.A., Grabell, J., Abshire, T., Flood, V., Haberichter, S.L., Lillicrap, D., O’Donnell, J/.S., Montgomery, R.R., James, P.D. Longitudinal Bleeding Assessment in von Willebrand Disease Utilizing an Interim Bleeding Score. J Thromb Haemost, 2022, in press. |
71. Quon D, Chitlur M, Rajpurkar M, Simpson M, O'Brien S, Flood V, Hsieh L, Acharya S, Kruse-Jarres R, Sood S, Maahs J. Women leaders in hematology: Inspirations & insights. Am J Hematol. 2016 Apr;91 Suppl 1:S6-S34. |
72. Lavin M, Christopherson P, Grabell J, Abshire T, Flood V, Haberichter SL, Lillicrap D, O'Donnell JS, Montgomery RR, James PD. Longitudinal bleeding assessment in von Willebrand disease utilizing an interim bleeding score. J Thromb Haemost. 2022 Oct;20(10):2246-2254. PMCID: PMC10193460 |
73. Christopherson PA, Haberichter SL, Flood VH, Sicking UO, Abshire TC, Montgomery RR, Zimmerman Program Investigators. Ristocetin dependent cofactor activity in von Willebrand disease diagnosis: Limitations of relying on a single measure. Res Pract Thromb Haemost. 2022 Oct;6(7):e12807. PMCID: PMC9637542 |
74. Sharma R, Flood V, Jobe S, Punzalan R, Simpson P, Conway C, Malec L. Utilization and optimization of an electronic self-administered bleeding assessment tool (E-Self BAT) for the screening of pediatric bleeding disorders in the hematology clinic. Haemophilia. 2023 Mar;29(2):685-688. |
75. Abou-Ismail MY, James PD, Flood VH, Connell NT. Beyond the guidelines: how we approach challenging scenarios in the diagnosis and management of von Willebrand disease. J Thromb Haemost. 2023 Feb;21(2):204-214. |
76. Sidonio RF Jr, Bryant PC, Di Paola J, Hale S, Heiman M, Horowitz GS, Humphrey C, Jaffray J, Joyner LC, Kasthuri R, Konkle BA, Kouides PA, Montgomery R, Neeves K, Randi AM, Scappe N, Tarango C, Tickle K, Trapane P, Wang M, Waters B, Flood VH. Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for mucocutaneous bleeding disorders. Expert Rev Hematol. 2023 Mar;16(sup1):39-54. |
77. Sadler B, Christopherson PA, Perry CL, Bellissimo DB, Haberichter SL, Haller G, Antunes L, Flood VH, Di Paola J, Montgomery RR. Characterization of copy-number variants in a large cohort of patients with von Willebrand disease reveals a relationship between disrupted regions and disease type Research and Practice in Thrombosis and Haemostasis. October 2023;7(7). |
78. Roberts JC, Christopherson PA, Tarantino MD, Gonzales SE, Morateck PA, Perry CL, Flood VH, Abshire TC, Montgomery RR, Zimmerman Program Investigators. Von Willebrand Factor (VWF) multiplex activity assay differentiation of type 1 von Willebrand Disease (VWD) and variant VWD. Haemophilia. 2024 Jan;30(1):161-168. PMCID: PMC10842138 |
79. Sadler B, Christopherson PA, Perry CL, Bellissimo DB, Haberichter SL, Haller G, Antunes L, Flood VH, Di Paola J, Montgomery RR, Zimmerman Program Investigators. Characterization of copy-number variants in a large cohort of patients with von Willebrand disease reveals a relationship between disrupted regions and disease type. Res Pract Thromb Haemost. 2023 Oct;7(7):102232. PMCID: PMC10704516 |
80. Christopherson PA, Tijet N, Haberichter SL, Flood VH, Ross J, Notley C, Rawley O, Montgomery RR, Zimmerman Project Investigators, James PD, Lillicrap D. The common VWF variant p.Y1584C: detailed pathogenic examination of an enigmatic sequence change. J Thromb Haemost. 2024 Mar;22(3):666-675. PMCID: PMC10922911 |
81. Sadler B, Christopherson PA, Perry CL, Bellissimo DB, Haberichter SL, Haller G, Antunes L, Flood VH, Di Paola J, Montgomery RR, Zimmerman Program Investigators. Characterization of copy-number variants in a large cohort of patients with von Willebrand disease reveals a relationship between disrupted regions and disease type. Res Pract Thromb Haemost. 2023 Oct;7(7):102232. PMCID: PMC10704516 |
82. Christopherson PA, Tijet N, Haberichter SL, Flood VH, Ross J, Notley C, Rawley O, Montgomery RR, Zimmerman Project Investigators, James PD, Lillicrap D. The common VWF variant p.Y1584C: detailed pathogenic examination of an enigmatic sequence change. J Thromb Haemost. 2024 Mar;22(3):666-675. PMCID: PMC10922911 |
83. Sharma R, Johnson V, Pan A, Sellers A, Betensky M, Goldenberg N, Flood VH. Assessment of rare bleeding disorders in adolescents with heavy menstrual bleeding. Haemophilia. 2024 Mar;30(2):490-496. |
84. Montgomery RR, Flood VH, Haberichter SL. Von Willebrand factor structure and function Textbook of von Willebrand Disease: Basic and Clinical Aspects. 1 January 2024:23-38. |
85. Clift H, Flood VH, Haberichter SL. Clinical and molecular markers of type 1C VWD Textbook of von Willebrand Disease: Basic and Clinical Aspects. 1 January 2024:123-128. |
86. Christopherson P, Montgomery RR, Flood VH. Molecular diagnosis of von Willebrand disease: The genotype Textbook of von Willebrand Disease: Basic and Clinical Aspects. 1 January 2024:109-114. |
87. Garcia J, Haberichter SL, Flood VH. Classification of VWD Textbook of von Willebrand Disease: Basic and Clinical Aspects. 1 January 2024:73-79. |
88. Janbain M, Haberichter SL, Flood VH. Clinical and molecular markers of type 2M VWD Textbook of von Willebrand Disease: Basic and Clinical Aspects. 1 January 2024:143-147. |
89. Branchford BR, Flood VH. Bleeding and Thrombosis Nelson Pediatric Symptom-Based Diagnosis: Common Diseases and their Mimics. 1 January 2022:942-964.e1. |
90. Seidizadeh O, Eikenboom JCJ, Denis CV, Flood VH, James P, Lenting PJ, Baronciani L, O'Donnell JS, Lillicrap D, Peyvandi F. von Willebrand disease. Nat Rev Dis Primers. 2024 Jul 25;10(1):51. |
91. Perry CL, Christopherson PA, Agostini TA, Haberichter SL, Montgomery RR, Flood VH. Prevalence and characterization of anti-VWF antibodies in a population of patients with type 3 VWD. Blood Adv. 2024 Oct 08;8(19):5051-5061. PMCID: PMC11459903 |
92. Joseph BC, Sekayan T, Falah N, Barnes RFW, Flood V, De Pablo-Moreno JA, von Drygalski A. Traumatic bleeding and mortality in mice are intensified by iron deficiency anemia and can be rescued with tranexamic acid Research and Practice in Thrombosis and Haemostasis. August 2024;8(6). |
93. Branchford BR, Samelson-Jones BJ, Flood VH. Disorders of the Blood Vessels Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
94. Samelson-Jones BJ, Branchford BR, Flood VH. Factor XI Deficiency Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3029-3034.e5. |
95. Branchford BR, Samelson-Jones BJ, Flood VH. Acquired Disorders of Platelet Function Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
96. Branchford BR, Samelson-Jones BJ, Flood VH. Neonatal Thrombocytopenia Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
97. Samelson-Jones BJ, Branchford BR, Flood VH. Factor VII Deficiency Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3029-3034.e5. |
98. Branchford BR, Samelson-Jones BJ, Flood VH. Immune Thrombocytopenia Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
99. Branchford BR, Samelson-Jones BJ, Flood VH. Congenital Abnormalities of Platelet Function Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
100. Samelson-Jones BJ, Branchford BR, Flood VH. Factor VIII or Factor IX Deficiency (Hemophilia A or B) Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3029-3034.e5. |
101. Samelson-Jones BJ, Branchford BR, Flood VH. Antiplasmin or Plasminogen Activator Inhibitor Deficiency Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3029-3034.e5. |
102. Branchford BR, Samelson-Jones BJ, Flood VH. Kasabach-Merritt Syndrome Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
103. Branchford BR, Samelson-Jones BJ, Raffini LJ, Flood VH. Clinical and Laboratory Evaluation of Hemostasis Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3023-3028.e1. |
104. Branchford BR, Samelson-Jones BJ, Flood VH. Hemolytic-Uremic Syndrome Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
105. Branchford BR, Samelson-Jones BJ, Flood VH. Platelet Function Disorders Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
106. Branchford BR, Flood VH. Von Willebrand Disease Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3035-3037.e1. |
107. Branchford BR, Samelson-Jones BJ, Flood VH. Thrombotic Thrombocytopenic Purpura Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
108. Branchford BR, Samelson-Jones BJ, Flood VH. Thrombocytopenia From Acquired Disorders Causing Decreased Production Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
109. Samelson-Jones BJ, Branchford BR, Flood VH. Congenital Fibrinogen Disorders Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3029-3034.e5. |
110. Branchford BR, Samelson-Jones BJ, Flood VH. Congenital Thrombocytopenic Syndromes Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
111. Branchford BR, Flood VH. Coagulopathy in Liver Disease Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3046-3046.e1. |
112. Samelson-Jones BJ, Branchford BR, Flood VH. Prothrombin (Factor II) Deficiency Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3029-3034.e5. |
113. Samelson-Jones BJ, Branchford BR, Flood VH. Deficiencies of the Contact Factors (Nonbleeding Disorders) Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3029-3034.e5. |
114. Branchford BR, Samelson-Jones BJ, Flood VH. Nonimmune Platelet Destruction Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
115. Samelson-Jones BJ, Branchford BR, Flood VH. Combined Deficiency of Factors V and VIII Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3029-3034.e5. |
116. Branchford BR, Samelson-Jones BJ, Flood VH. Postneonatal Vitamin K Deficiency Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3046-3046.e1. |
117. Branchford BR, Flood VH. Acquired Inhibitors of Coagulation Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3047-3047.e2. |
118. Branchford BR, Samelson-Jones BJ, Flood VH. Sequestration Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
119. Branchford BR, Samelson-Jones BJ, Flood VH. Drug-Induced Thrombocytopenia Nelson Textbook of Pediatrics: Volume 1-2. 1 January 2024:3049-3060.e1. |
120. Roberts, J.C., Christopherson, P.A., Tarantino, M.D., Gonzales, S.E., Morateck, P.A., Perry, C.L., Flood, V.H., Abshire, T.C., Montgomery, R.R., and the Zimmerman Program Investigators. Von Willebrand Factor (VWF) Multiplex Activity Assay Differentiation of Type 1 von Willebrand Disease (VWD) and Variant VWD. Haemophilia 30(1):161-168, 2024. |
121. Sharma, R.; Johnson, V., Pan, A., Sellers, A., Betensky, M/, Goldenberg, N., Flood, V. Assessment of Rare Bleeding Disorders in Adolescents with Heavy Menstrual Bleeding. Haemophilia 30(2):490-496, 2024. |
122. Christopherson, P.A., Tijet, N., Haberichter, S.L., Flood, V.H., Ross, J., Notley, C., Rawley, O., Montgomery, R.R., Zimmmerman Program Investigators, James, P.D., Lillicrap D. The Common VWF Varient p.Y1584C: Detailed Pathogenic Examination of an Enigmatic Sequence Change. J Thromb Haemost, 22(3):666-675, 2024 |
123. Perry, C.L, Christopherson, P.A., Agostini, T.A., Haberichter, S.L, Montgomery, R.R., Flood, V.H. The Prevalence and Characterization of anti-VWF Antibodies in a Population of Subjects with Type 3 VWD. Blood Advance, 2024, in press. |
124. Seidizadeh, O., Eikenboom, J.C.J., Denis, C.V., Flood, V.H., James, P., Lenting, P.J., Baronciani L,, O’Donnell, J.S., Lillicrap, D., Peyvandi, F. von Willebrand disease. Nat Rev Dis Primers, 2024, in press. |
125. Traumatic Bleeding and Mortality in Mice Are Intensified by Iron Deficiency Anemia and Can Be Rescued With Tranexemic Acid. Res Pract Thromb Haemost 2024 in press. |
126. Clearfield E, Kim B, Ford S, Connell NT, Santaella ME, Lavin M, Degenaar-Dujardin MEL, Ayoub E, Flood VH, Rotellini D, Skinner MW, James P, coreVWD Panel. A core outcome set for prophylaxis and perioperative treatment of von Willebrand disease: The coreVWD initiative. Haemophilia. 2024 Nov;30(6):1357-1365. |
Books, Chapters, and Reviews |
1. Flood VH. In: Blueprints Q&A Step 2: Pediatrics. Blackwell Science. Malden, MA; 2002, contributor. |
2. Flood VH. In: Blueprints Q&A Step 3: Pediatrics. Blackwell Science. Malden, MA; 2002, contributor. |
3. Flood VH, Montgomery RR. In: Von Willebrand Disease: Biological Diagnosis. Lee C, Berntorp E, Hoots K (eds). Textbook of Hemophilia, 2nd edition. Oxford, UK: Wiley. Revised chapter for 3rd edition submitted December 2012. |
4. Flood VH, Recht M. Autoimmune Hemolytic Anemia. Textbook of Clinical Pediatrics, 2nd edition. Elzouki, A.Y., ed. Springer; New York, NY, 2011. |
5. Punzalan RC, Flood VH. Developmental Hemostasis. Textbook of Clinical Pediatrics, 2nd edition. Elzouki, A.Y., ed. Springer; New York, NY, 2011. |
6. Flood, VH, Gill, JC, Friedman, KD, Bellissimo, DB, Haberichter, SL, Montgomery,RR. Von Willebrand Disease in the United States: A Perspective from Wisconsin. Seminars in Thrombosis and Hemostasis, 37(5):528-534 , 2011.
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7. Bemtorp E, Fuchs B, Makris M, Montgomery RR, Flood V, O'Donnell JS, Federici AB, Lillicrap D, James P, Budde U, Morfini M, Petrini P, Austin S, Kannicht C, Jimenez-Yuste V, Lee C. Third Aland Islands Conference on Von Willebrand Disease, 26-28 September 2012: Meeting Report. Haemophilia, 19 (Suppl 3): 1-18, 2013. |
8. Flood VH, Perils, Problems and Progress in Laboratory Diagnosis of Von Willebrand Disease. Seminars in Thrombosis and Hemostasis, 2014, in press.
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9. Flood, V.H., Montgomery, R.R. Von Willebrand Disease: Biological Diagnosis. Textbook of Hemophilia, 3rd edition. Lee, C., Berntorp, E., Hoots, K., eds. Wiley-Blackwell; Oxford, UK, 2014. (Revision of chapter from previous edition.) |
10. Flood, V.H., Scott, J.P. Von Willebrand Disease. Nelson Textbook of Pediatrics, 20th edition. Kleigman, R., Stanton, B., St. Geme III, J. Schor, N., eds. Elsevier; in press.
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Abstracts |
1. Flood, V.H. Anemia and Jaundice in a Two Year Old Boy. Mayo Clinic Scottsdale Academic Excellence Day, 2001. Poster presentation, Scottsdale, AZ, 05/2001. |
2. Flood, V.H. The Case of the Swollen Knee. Mayo Clinic Scottsdale Academic Excellence Day, 2002. Poster presentation, Scottsdale, AZ, 05/2002. |
3. Flood VH, Johnson FL, Boshkov LK, Nugent DJ, Thomas GA, Nicholson HS, Tilford D, Godder KT. Sustained Engraftment Post Bone Marrow Transplant Despite Anti-Platelet Antibodies in Glanzmann Thrombasthenia. Pediatr Blood Cancer. 42(6):507, 2004. Poster presentation for the American Society of Pediatric Hematology/Oncology, San Francisco, CA, 05/2004. |
4. Flood VH, Al-Mondhiry HA, Farrell DH. The Paradoxical Hemorrhagic and Thrombotic Nature of the Fibrinogen AaR16C Mutation. Blood 104(11):1047, 2004. Poster presentation for the American Society of Hematology, San Diego, CA, 12/2004. |
5. Sheppard, A, Flood, V Characterization of Variant Fibrinogens. Northwest Undergraduate Science Research Conference, 2005. Oral presentation, Portland, OR, 04/2005. |
6. Flood VH, Al-Mondhiry HA, Farrell DH. The Fibrinogen AaR16C Mutation Results in Fibrinolytic Resistance. Journal of Thrombosis and Haemostasis 3 (Supplement 1):109, 2005. Oral presentation for the International Society on Thrombosis and Haemostasis, Sydney, Australia , 08/2005. |
7. Flood VH, Al-Mondhiry HA, Bakke AC, Farrell DH. Fibrinogen Hershey IV: A Novel Dysfibrinogen with a yV4111 Mutation in the Integrin allb/h Binding Site. Blood 106(11):2133, 2005. Poster presentation for the American Society of Hematology, Atlanta , GA,12/2005. |
8. Flood, V.H., Galderisi, F.C., Lowas, S.R., Boshkov, L.K. Late Hemorrhagic Disease of the Newborn in Two Patients Receiving Vitamin K at Birth: Recognition and Treatment with Recombinant Factor VIla, Vitamin K, and Plasma. Hemophilia and Thrombosis Research Society, 2006. Poster presentation, Chicago, IL, 04/2006.
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9. Johnson C, Flood V Characterization of Acquired Dysfibrinogenemia in Liver Cirrhosis. Northwest Undergraduate Science Research Conference, 2006. Oral presentation, Portland, OR, 04/2006. |
10. Flood VH, Nagaswami C, Chernysh IN, Al-Mondhiry HA, Weisel JW, Farrell DH. Effects of Impaired Fibrinopeptide A Cleavage on Fibrin Clot Structure: Studies with an AaR16C Dysfibrinogen. Blood 108(11): 1617, 2006. Poster presentation for the American Society of Hematology, Orlando, FL, 12/2006. |
11. Branchford, B.R., Kautza, B.C., Gill, J.C., Flood, V.H., Friedman, K.D., Lee, A., Morateck, P., Christopherson, P.A., Montgomery, R.R. Racial Disparity in the Diagnosis of von Willebrand Disease (VWD) with Particular Reference to the Diagnosis of Type 2M VWD in African Americans. Pediatric Academic Society, 2007. Poster presentation, Toronto, Canada, 05/2007. |
12. Montgomery RR, Morateck P, Christopherson PA, Kautza BC, Miller CA, Branchford BR, Flood VH, Haberichter SL, Bellissimo DB, Friedman KD, Kenny DJ, Gill JC. Functional Assay of VWF Measured by its Interaction with Platelet GPIb without the Use of Ristocetin. Blood 110(11):5212 2007. Oral presentation for the American Society of Hematology, Atlanta, GA, 12/2007. |
13. Bellissimo DB, Christopherson PA, Haberichter SL, Flood VH, Gill JC, Friedman KD, Abshire TC, Di Paola JA, Hoots WK, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Montgomery RR. Novel VWF Sequence Variations Identified in Normal Controls and Index Cases Enrolled in the TS Zimmerman Program for the Molecular and Clinical Biology of VWD (ZPMCB-VWD). Blood 110(11):709, 2007. Oral presentation for the American Society of Hematology, Atlanta, GA, 12/2007. |
14. Flood VH, Kautza BC, Miller CA, Branchford BR, Gill JC, Haberichter SL, Morateck PA, Christopherson PA, Perry CL, Friedman KD, Bellissimo DB, Abshire TC, Di Paola JA, Hoots WK, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Lillicrap D, Goodeve AC, Peake IR, Montgomery RR. Common VWF Haplotypes in Normal African-Americans and Caucasians Recruited into the ZPMCB-VWD and Their Impact on VWF Laboratory Testing. Blood 110(1 1):714, 2007. Oral presentation for the American Society of Hematology, Atlanta, GA, 12/2007 |
15. Flood, VH, Kautza BC, Miller CA, Branchford BR, Gill JC, Haberichter SL, Morateck PA, Christopherson PA, Perry CL, Friedman KD, Bellissimo DB, Abshire TC, Lusher JM, Hoots WK, Shapiro AD, DiPaola JA, Leissinger C, Ragni MV, Lillicrap D, Goodeve AC, Peake IR, Montgomery RR The Impact of Common VWF Polymorphisms in African Americans and Caucasians on Laboratory Tests of VWF Function. Poster presentation for the Gordon Research Conference on Hemostasis, Waterville Valley, NH, 07/2008. |
16. Flood VH, Morateck PA, Christopherson PA, Friedman KD, Gill JC, Montgomery RR, and the Zimmerman Program Investigators. Unique ELISA-Based Assays for VWF-GPIb Interactions and the Impact of Racial Differences on VWF Testing. Blood 112(11):423, 2008. Oral presentation for the American Society of Hematology, San Francisco, CA, 12/2008. |
17. Gill JC, Christopherson PA, Flood VH, Friedman KD, Montgomery RR, and the Zimmerman Program Investigators. Bleeding Scores in von Willebrand Disease (VWD) Re-visited: Analysis of the TS Zimmerman Program for the Molecular and Clinical Biology of VWD. Blood 112(11):425, 2008. Oral presentation for the American Society of Hematology , San Francisco, CA, 12/2008 |
18. Flood VH, Morateck PA, Christopherson PA, Gill JC, Friedman KD, Montgomery RR, Zimmerman Program Investigators. Functional Assays for Discrimination of Type 2 VWD Variants. J Thromb Haemost.7(Supplement 2):2479, 2009. Oral presentation for the International Society on Thrombosis and Haemostasis, Boston, MA, 07/2009 |
19. Flood VH, Lederman CA, Wren JS, Christopherson PA, Friedman KD, Montgomery RR. A Novel VWF A3 Domain Mutation with Absent Binding to Type I and Type III Collagen. Blood 114(22):541, 2009 Oral presentation for the American Society of Hematology, New Orleans, LA, 12/2009 |
20. Flood, V.H., Lederman, C.A., Wren, J.S., Christopherson, P.A., Friedman, K.D., Montgomery, R.R. Absent Collagen Binding in a VWF A3 Domain Mutant: Utility of the VWF:CB in Diagnosis of VWD. Gordon Research Conference, 2010. Poster presentation for the Gordon Research Conference on Hemostasis, Waterville Valley, NH, 07/2010 |
21. Friedman KD, Bellissimo DB, Christopherson PA, Flood VH, Gill JC, Montgomery RR, Haberichter SL. Fourteen Percent of Healthy African Americans Participating in the Zimmerman Program for the Molecular and Clinical Biology of VWD (ZPMCB-VWD) are Heterozygous for the VWF Gene Mutation H817Q Associated with Type 2N von Willebrand Disease. Blood (ASH Annual Meeting Abstracts). 12/2010;116(21):239 |
22. Flood VH, Wren JS, Haberichter SL, Friedman KD, Bellissimo DB, Gill JC, Hoffmann RG, Scott JP, Montgomery RR. Low VWF:RCo in Subjects with VWF Polymorphisms P1472H and P1467S Due to Decreased Binding of Ristocetin to the VWF A1 Domain. Blood 116(21):2208, 2010 Poster presentation for the American Society of Hematology, Orlando, FL, 12/2010. |
23. Flood VH, Haberichter SL, Friedman KD, Lentz SR, Gill JC, Montgomery RR. VWF Binding to Types I, III, or VI Collagen in the ZPMCB-VWD with Identification of Subjects with Selective Reduced Plasma VWF:CB. Blood 116(21):235,2010 Oral presentation for the American Society of Hematology, Orlando, FL, 12/2010. |
24. Flood VH, Haberichter SL, Friedman KD, Lentz SR, Hoffmann RG, Gill JC, Montgomery RR. Utility of von Willebrand Factor Collagen Binding Assays (VWF:CB) with Type VI Collagen in the Diagnosis of VWD. J Thromb Haemost 9(Supplement 2):455, 2011. Poster presentation for the International Society on Thrombosis and Haemostasis, Kyoto, Japan, 07/2011. |
25. Haberichter SL, Jacobi PM, Flood VH, Christopherson PA, Gill JC, Bellissimo DB, Friedman KD, Zimmerman Program Investigators. Quantitative Analysis of VWF Multimer Structure: Discrimination Between VWD Subtypes. Blood 118(21): 1215, 2011. Poster presentation for the American Society of Hematology, San Diego, CA, 12/2011.
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26. Flood VH, Gill JC, Friedman KD, Christopherson PA, Jacobi PM, Montgomery RR, Haberichter SL. Von Willebrand Factor Collagen Binding Provides a Sensitive Screen for Identification of Type 2A and 2B Von Willebrand Disease. Blood 118(21):379, 2011. Oral presentation for the American Society of Hematology, San Diego, CA, 12/2011 |
27. Montgomery RR, Christopherson PA, Haberichter SL, Flood VH, Gill JC, Zimmerman Program Investigators. Diagnostic Fidelity of Historically Diagnosed Patients with VWD Enrolled from 27 Centers in the ZPMCB-VWD. Blood. 118(21):381, 2011. Oral
presentat ion for the American Society of Hematology, San Diego, CA, 12/2011.
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28. Franzblau EB, Punzalan RC, Friedman KD, Flood VH Inter-Laboratory Variability in Measurement of Fibrinogen Following Purified Fibrinogen Concentrate for Dysfibrinogenemia. Pediatr Blood Cancer 58(7):559, 2012. Poster presentation for the American Society of Pediatric Hematology/Oncology, New Orleans, LA, 05/2012. |
29. Larsen DM, Wren JS, Morateck PA, Perry CL, Haberichter SL, Flood VH Type 2M Von Willebrand Disease Encompasses a Spectrum of Functional Defects. Pediatr Blood Cancer 58(7):407, 2012. Oral presentation for the American Society of Pediatric/Hematology/Oncology, New Orleans, LA, 05/2012. |
30. Flood VH, Gill JC, Haberichter SL, Bellissimo DB, Christopherson PA, Friedman KD, Montgomery RR, and the Zimmerman Program Investigators. Binding of VWF to Type IV Collagen: An Additional Collagen Binding Mechanism Beyond Types I, Ill and VI Collagen? Oral presentation for the American Society of Hematology, New Orleans, LA, 12/2013. |
31. Flood VH, Schlauderaff AC, Jacobi PM, Slobodianuk TS, Montgomery, RR, Haberichter, SL, and the Zimmerman Program Investigators. VWF Interaction With Type IV Collagen Is Mediated Through Critical VWF AI Domain Residues. Oral presentation for the American Society of Hematology, New Orleans, LA, 12/2013.
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32. Montgomery, RR, Haberichter SL, Hille M, Morateck P, Scott JP, Flood VH Alanine Scanning Mutagenesis of the VWF-AI Flanking Regions of VWF and the Impact on Ristocetin-induced VWF Interaction with Platelets. Poster presentation for the American Society of Hematology, New Orleans, LA, 12/2013. |
33. Montgomery RR, Christopherson, PA, Bellissimo DB, Gill JC, Haberichter SL, Flood VH, Lillicrap, D, Goodeve AC, Friedman KD, Abshire TC, Shapiro AD, Ragni MV, Lentz SR, Leissinger CA, Dunn AL, Lusher J, Brown D. The Complete Type I VWD Cohort of the Zimmerman Program for the Molecular and Clinical Biology of VWD-Phenotypic Assignment, Mutation Frequency, and Bleeding Assessment. Oral presentation for the American Society of Hematology, New Orleans, LA, 12/2013. |
34. Haberichter SL, Christopherson PA, Flood VH, Gill JC, Bellissimo DB, Friedman KD, Montgomery RR, and the Zimmerman Program Investigators. Critical Importance of VWF Propeptide (VWFpp) in the Diagnosis of Type I von Willebrand Disease (VWD). Oral presentation for the American Society of Hematology, New Orleans, LA, 12/2013. |
35. Flood, V.H., Gill, J.C., Christopherson, P.A., Bellissimo, D.B., Friedman, K.D., Haberichter, S.L., Udani, R., Montgomery, R.R., and the Zimmerman Program Investigators. Update on Bleeding Scores in the Zimmerman Program: Comparison of ISTH BAT, PBQ, and MCMDM-1VWD Scoring Systems. Journal of Thrombosis and Haemostasis 12 (Supplement 1):95 (VWF16), 2014. Poster presentation for the International Society on Thrombosis and Haemostasis, Milwaukee, WI, 06/2014. |
36. Schlauderaff, A.C, Haberichter, S.L., Slobodianuk, T.L., Morateck, P.A., Montgomery, R.R., Flood, V.H., and the Zimmerman Program Investigators. Overlap of Collagen 4 and Platelet Binding Sites in VWF A1 Domain. Journal of Thrombosis and Haemostasis 12 (Supplement 1):94 (VWF14), 2014. Poster presentation for the International Society on Thrombosis and Haemostasis, Milwaukee, WI, 06/2014. |
37. Christopherson, P.A., Flood, V.H., Gill, J.C., Friedman, K.D., Haberichter, S.L., Montgomery, R.R., and the Zimmerman Program Investigators. Improved Diagnosis of VWD in Affected Family Members Using the ISTH Bleeding Score. Journal of Thrombosis and Haemostasis 12 (Supplement 1):95 (VWF17), 2014. Poster presentation for the International Society on Thrombosis and Haemostasis, Milwaukee, WI, 06/2014. |
38. Flood, V.H., Christopherson, P.A., Bellissimo, D.B., Gill, J.C., Habericter, S.L., Friedman, K.D., Udani, R.A., Roberts, J.C., Montgomery, R.R., and the Zimmerman Program Investigators. Spectrum of Type 2 von Willebrand Disease in the Zimmerman Program. Blood 124, 2014. Oral presentation for the American Society of Hematology, San Francisco, CA, 12/2014.
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39. Bellissimo, D.B., Udani, R., Christopherson, P.A., Friedman, K.D., Gill, J.C., Habericter, S.L., Montgomery, R.R., Flood, V.H., and the Zimmerman Program Investigators. Phenotypic Variability in Carriers of Von Willebrand Factor Truncating Variants in the Zimmerman Program. Blood 124, 2014. Poster presentation for the American Society of Hematology, San Francisco, CA, 12/2014. |
40. Christopherson, P.A., Flood, V.H., Friedman, K.D., Gill, J.C., Haberichter, S.L., Montgomery, R.R., Abshire, T.C., and the Zimmerman Program Investigators. Impact of Age and Gender on Bleeding Score in Type 1 VWD Using the ISTH-BAT. Blood 124, 2014. Poster presentation for the American Society of Hematology, San Francisco, CA, 12/2014 |
41. Christopherson, P.A., Abshire, T.C., Flood, V.H., Haberichter, S.L., Montgomery, R.R., and the Zimmerman Program Investigators. Diagnosis of VWD Based on a Single Low VWF:RCo in the Zimmerman Program Comparative Effectiveness Study. Res Pract Thromb Haemost 3(Suppl 1):88;OC13.1, 2019. Oral presentation for the International Society on Thrombosis and Haemostasis, Melbourne, Australia, 07/2019. |
42. Gill, J.C., Conley, S., Christopherson, P.A., Haberichter, S.L., Zhang, J., Simpson, P., Abshire, T.A., Montgomery, R.R., Flood, V.H. Low von Willebrand Levels Do Not Predict Bleeding in Children Undergoing Tonsillectomy. Res Pract Thromb Haemost 3(Suppl 1):378;PB0782, 2019. Poster presentation for the International Society on Thrombosis and Haemostasis, Melbourne, Australia, 07/2019. |
43. *DiGiandomenico, S., Christopherson, P.A., Haberichter, S.L., Abshire, T.C., Montgomery, R.R., Flood, V.H. and the Zimmerman Program Investigators. Variable Accuracy of Type 2 Von Willebrand Disease Diagnosis. Res Pract Thromb Haemost 3(Suppl 1):388;PB0798, 2019. Poster presentation for the International Society on Thrombosis and Haemostasis, Melbourne, Australia, 07/2019. |
44. *Brown, M.C., Christopherson, P.A., Abshire, T.C., Flood, V.H., Montgomery, R.R., Sidonio Jr., R. F. Poor DDAVP Response Does Not Explain Elevated Bleeding Scores in Persons with Low von Willebrand Factor. Res Pract Thromb Haemost 3(Suppl 1):396;PB0813, 2019. Poster presentation for the International Society on Thrombosis and Haemostasis, Melbourne, Australia, 07/2019 |
45. *Kalot, M.A., Al-Khatib, M., Connell, N.T., Flood, V.H., Brignardello-Peterson, R., Clark, C., Castano, J., Riker, E., Robinson, F., Skinner, M., James, P., Mustafa, R.A. Von Willebrand Disease: An International Survey Assessing the Important Topics for Decision-Making. Res Pract Thromb Haemost 3(Suppl 1):398;PB0817, 2019. Poster presentation for the International Society on Thrombosis and Haemostasis, Melbourne, Australia, 07/2019. |
46. *Kalot, M.A., Al-Khatib, M., Connell, N.T., Flood, V.H., Brignardello-Peterson, R., Clark, C., Castano, J., Riker, E., Robinson, F., Skinner, M., James, P., Mustafa, R.A. Von Willebrand Disease: An International Survey Assessing the Important Topics for Decision-Making. Poster presentation for the National Hemophilia Foundation, Orlando, FL, 10/2019. |
47. Sharma, R., Menon, S., Dobratz, M., Hansen, B., Johnson, V., Flood, V.H. Assessment of Rare Bleeding Disorders in Adolescent Females with Unexplained Bleeding. Oral presentation for the Thrombosis and Hemostasis Society of North America, Chicago, IL, 04/2020. (**rescheduled due to COVID-19). |
48. *DiGiandomenico, S.M., Conley, S.F., Johnson, V.P., Christopherson, P.A., Zhang, J., Simpson, P., Abshire, T.C., Montgomery, R.R., Flood, V.H. VWF Levels in Children with Postoperative Bleeding Following Tonsillectomy. Poster presentation for the American Society of Pediatric Hematology/Oncology, Austin, TX, 05/2020. (**cancelled due to COVID-19). |
49. Christopherson, P., Flood, V.H., Haberichter, S., Slobodianuk, T., Morateck, P., Montgomery, R. and the Zimmerman Program Investigators. Characterization of Type 2B VWD in the US Zimmerman Program. Poster presentation for the International Society on Thrombosis and Haemostasis, Milan, Italy, 07/2020. (**virtual due to COVID-19). |
50. Flood, V.H.. et al. : Lack of Congruent VWF Levels, Geneitcs, and Bleeding Symptoms in Families with a Type 1 von Willebrand Disease Diagnosis. Poster presentation for the International Society on Thrombosis and Haemostasis, 07/2022. |
51. Haberichter, S. et al. : Quantitative multimers in the diagnosis of VWD. Poster presentation for the International Society on Thrombosis and Haemostasis, 07/2022. |
52. Christopherson, P. et al. : Performance of the ISTH_Bat bleeding score in a poulatio of newly diagnosed VWD in the U.S. Zimmerman Program. Poster presentation for the International Society on Thrombosis and Haemostasis, 07/2022. |
