Medical College of Wisconsin
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Aaron D. Mickle PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Physiology


Publications (26)

  • Acute ampakines increase voiding function and coordination in a rat model of SCI. (Rana S, Alom F, Martinez RC, Fuller DD, Mickle AD) Elife 2024 Mar 07;12 PMID: 38451184 PMCID: PMC10962400 SCOPUS ID: 2-s2.0-85187207646 03/07/2024       2 Citations
  • Hypertension and urologic chronic pelvic pain syndrome: An analysis of MAPP-I data. (Conic RRZ, Vasilopoulos T, Devulapally K, Przkora R, Dubin A, Sibille KT, Mickle AD) BMC Urol 2024 Jan 28;24(1):21 PMID: 38281923 PMCID: PMC10822153 SCOPUS ID: 2-s2.0-85183341759 01/29/2024    
  • Optogenetic urothelial cell stimulation induces bladder contractions and pelvic nerve afferent firing. (Robilotto GL, Yang OJ, Alom F, Johnson RD, Mickle AD) Am J Physiol Renal Physiol 2023 Aug 01;325(2):F150-F163 PMID: 37318991 SCOPUS ID: 2-s2.0-85164303227 06/15/2023       3 Citations
  • Acute ampakines increase voiding function and coordination in a rat model of SCI. (Rana S, Alom F, Martinez RC, Fuller DD, Mickle AD) bioRxiv 2023 Nov 17 PMID: 37293023 PMCID: PMC10245998 06/09/2023    
  • Evaluating the transduction efficiency of systemically delivered AAV vectors in the rat nervous system. (Yang OJ, Robilotto GL, Alom F, Alemán K, Devulapally K, Morris A, Mickle AD) Front Neurosci 2023;17:1001007 PMID: 36755734 PMCID: PMC9899837 SCOPUS ID: 2-s2.0-85147436634 02/10/2023       4 Citations
  • Role of Src kinase in regulating protein kinase C mediated phosphorylation of TRPV1. (Robilotto GL, Mohapatra DP, Shepherd AJ, Mickle AD) Eur J Pain 2022 Oct;26(9):1967-1978 PMID: 35900227 PMCID: PMC9483845 SCOPUS ID: 2-s2.0-85135524078 07/29/2022       7 Citations
  • Open source timed pressure control hardware and software for delivery of air mediated distensions in animal models. (Patel T, Hendren J, Lee N, Mickle AD) HardwareX 2022 Apr;11:e00271 PMID: 35509929 PMCID: PMC9058729 SCOPUS ID: 2-s2.0-85124207731 05/06/2022    
  • Characterization of a method to study urodynamics and bladder nociception in male and female mice. (Srivastava P, Lai HH, Mickle AD) Low Urin Tract Symptoms 2021 Apr;13(2):319-324 PMID: 33202486 PMCID: PMC8474011 SCOPUS ID: 2-s2.0-85096720870 11/18/2020       1 Citation
  • Battery-free, fully implantable optofluidic cuff system for wireless optogenetic and pharmacological neuromodulation of peripheral nerves. (Zhang Y, Mickle AD, Gutruf P, McIlvried LA, Guo H, Wu Y, Golden JP, Xue Y, Grajales-Reyes JG, Wang X, Krishnan S, Xie Y, Peng D, Su CJ, Zhang F, Reeder JT, Vogt SK, Huang Y, Rogers JA, Gereau RW 4th) Sci Adv 2019 Jul;5(7):eaaw5296 PMID: 31281895 PMCID: PMC6611690 SCOPUS ID: 2-s2.0-85068588571 07/10/2019       117 Citations
  • A wireless closed-loop system for optogenetic peripheral neuromodulation. (Mickle AD, Won SM, Noh KN, Yoon J, Meacham KW, Xue Y, McIlvried LA, Copits BA, Samineni VK, Crawford KE, Kim DH, Srivastava P, Kim BH, Min S, Shiuan Y, Yun Y, Payne MA, Zhang J, Jang H, Li Y, Lai HH, Huang Y, Park SI, Gereau RW 4th, Rogers JA) Nature 2019 Jan;565(7739):361-365 PMID: 30602791 PMCID: PMC6336505 SCOPUS ID: 2-s2.0-85060148196 01/04/2019       350 Citations
  • A bright future? Optogenetics in the periphery for pain research and therapy. (Mickle AD, Gereau RW 4th) Pain 2018 Sep;159 Suppl 1(Suppl 1):S65-S73 PMID: 30113949 PMCID: PMC6097536 SCOPUS ID: 2-s2.0-85064486300 08/17/2018       21 Citations
  • Macrophage angiotensin II type 2 receptor triggers neuropathic pain. (Shepherd AJ, Mickle AD, Golden JP, Mack MR, Halabi CM, de Kloet AD, Samineni VK, Kim BS, Krause EG, Gereau RW 4th, Mohapatra DP) Proc Natl Acad Sci U S A 2018 Aug 21;115(34):E8057-E8066 PMID: 30082378 PMCID: PMC6112686 SCOPUS ID: 2-s2.0-85051790113 08/08/2018       97 Citations
  • Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain. (Shepherd AJ, Copits BA, Mickle AD, Karlsson P, Kadunganattil S, Haroutounian S, Tadinada SM, de Kloet AD, Valtcheva MV, McIlvried LA, Sheahan TD, Jain S, Ray PR, Usachev YM, Dussor G, Krause EG, Price TJ, Gereau RW 4th, Mohapatra DP) J Neurosci 2018 Aug 08;38(32):7032-7057 PMID: 29976627 PMCID: PMC6083458 SCOPUS ID: 2-s2.0-85051586513 07/07/2018       84 Citations
  • Parathyroid hormone-related peptide activates and modulates TRPV1 channel in human DRG neurons. (Shepherd AJ, Mickle AD, McIlvried LA, Gereau RW 4th, Mohapatra DP) Eur J Pain 2018 Oct;22(9):1685-1690 PMID: 29797679 SCOPUS ID: 2-s2.0-85053414226 05/26/2018       7 Citations
  • Parathyroid Hormone-Related Peptide Elicits Peripheral TRPV1-dependent Mechanical Hypersensitivity. (Shepherd AJ, Mickle AD, Kadunganattil S, Hu H, Mohapatra DP) Front Cell Neurosci 2018;12:38 PMID: 29497363 PMCID: PMC5818411 SCOPUS ID: 2-s2.0-85043586891 03/03/2018       19 Citations
  • Miniaturized, Battery-Free Optofluidic Systems with Potential for Wireless Pharmacology and Optogenetics. (Noh KN, Park SI, Qazi R, Zou Z, Mickle AD, Grajales-Reyes JG, Jang KI, Gereau RW 4th, Xiao J, Rogers JA, Jeong JW) Small 2018 Jan;14(4) PMID: 29215787 PMCID: PMC5912318 SCOPUS ID: 2-s2.0-85040970185 12/08/2017       96 Citations
  • Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain. (Samineni VK, Mickle AD, Yoon J, Grajales-Reyes JG, Pullen MY, Crawford KE, Noh KN, Gereau GB, Vogt SK, Lai HH, Rogers JA, Gereau RW 4th) Sci Rep 2017 Nov 20;7(1):15865 PMID: 29158567 PMCID: PMC5696510 SCOPUS ID: 2-s2.0-85034640184 11/22/2017       40 Citations
  • Fully implantable, battery-free wireless optoelectronic devices for spinal optogenetics. (Samineni VK, Yoon J, Crawford KE, Jeong YR, McKenzie KC, Shin G, Xie Z, Sundaram SS, Li Y, Yang MY, Kim J, Wu D, Xue Y, Feng X, Huang Y, Mickle AD, Banks A, Ha JS, Golden JP, Rogers JA, Gereau RW 4th) Pain 2017 Nov;158(11):2108-2116 PMID: 28700536 PMCID: PMC5640477 SCOPUS ID: 2-s2.0-85040794230 07/13/2017       81 Citations
  • Flexible Near-Field Wireless Optoelectronics as Subdermal Implants for Broad Applications in Optogenetics. (Shin G, Gomez AM, Al-Hasani R, Jeong YR, Kim J, Xie Z, Banks A, Lee SM, Han SY, Yoo CJ, Lee JL, Lee SH, Kurniawan J, Tureb J, Guo Z, Yoon J, Park SI, Bang SY, Nam Y, Walicki MC, Samineni VK, Mickle AD, Lee K, Heo SY, McCall JG, Pan T, Wang L, Feng X, Kim TI, Kim JK, Li Y, Huang Y, Gereau RW 4th, Ha JS, Bruchas MR, Rogers JA) Neuron 2017 Feb 08;93(3):509-521.e3 PMID: 28132830 PMCID: PMC5377903 SCOPUS ID: 2-s2.0-85010840004 01/31/2017       315 Citations
  • Stretchable multichannel antennas in soft wireless optoelectronic implants for optogenetics. (Park SI, Shin G, McCall JG, Al-Hasani R, Norris A, Xia L, Brenner DS, Noh KN, Bang SY, Bhatti DL, Jang KI, Kang SK, Mickle AD, Dussor G, Price TJ, Gereau RW 4th, Bruchas MR, Rogers JA) Proc Natl Acad Sci U S A 2016 Dec 13;113(50):E8169-E8177 PMID: 27911798 PMCID: PMC5167187 SCOPUS ID: 2-s2.0-85006042924 12/03/2016       110 Citations
  • Nociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain Pathologies. (Mickle AD, Shepherd AJ, Mohapatra DP) Pharmaceuticals (Basel) 2016 Nov 14;9(4) PMID: 27854251 PMCID: PMC5198047 SCOPUS ID: 2-s2.0-84997294311 11/18/2016       98 Citations
  • Induction of thermal and mechanical hypersensitivity by parathyroid hormone-related peptide through upregulation of TRPV1 function and trafficking. (Mickle AD, Shepherd AJ, Loo L, Mohapatra DP) Pain 2015 Sep;156(9):1620-1636 PMID: 25970319 PMCID: PMC5070921 SCOPUS ID: 2-s2.0-84964617156 05/15/2015       23 Citations
  • Sensory TRP channels: the key transducers of nociception and pain. (Mickle AD, Shepherd AJ, Mohapatra DP) Prog Mol Biol Transl Sci 2015;131:73-118 PMID: 25744671 PMCID: PMC5903472 SCOPUS ID: 2-s2.0-84924581659 03/07/2015       108 Citations
  • Interference with peroxisome proliferator-activated receptor-γ in vascular smooth muscle causes baroreflex impairment and autonomic dysfunction. (Borges GR, Morgan DA, Ketsawatsomkron P, Mickle AD, Thompson AP, Cassell MD, Mohapatra DP, Rahmouni K, Sigmund CD) Hypertension 2014 Sep;64(3):590-6 PMID: 24914194 PMCID: PMC4134389 SCOPUS ID: 2-s2.0-84907598119 06/11/2014       12 Citations
  • Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics. (Shepherd AJ, Loo L, Gupte RP, Mickle AD, Mohapatra DP) J Neurosci 2012 Dec 05;32(49):17725-39 PMID: 23223293 PMCID: PMC3544972 SCOPUS ID: 2-s2.0-84870542038 12/12/2012       30 Citations
  • The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel. (Loo L, Shepherd AJ, Mickle AD, Lorca RA, Shutov LP, Usachev YM, Mohapatra DP) J Neurosci 2012 Aug 29;32(35):11942-55 PMID: 22933780 PMCID: PMC3461320 SCOPUS ID: 2-s2.0-84865469570 08/31/2012       41 Citations
  • Last update: 07/03/2024