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Alan Bloom PhD, MA
Emeritus Professor
Institution:
Medical College of Wisconsin
Department:
Pharmacology and Toxicology
Member of the
Neuroscience Research Center
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Publications (55)
Perceived cognitive changes with chemotherapy for breast cancer: A pilot study.
(Piacentine LB, Miller JF, Haberlein S, Bloom AS)
Appl Nurs Res
2016 Feb;29:9-11 PMID: 26856481 SCOPUS ID: 2-s2.0-84958801324 02/10/2016
10 Citations
Responses of dopaminergic, serotonergic and noradrenergic networks to acute levo-tetrahydropalmatine administration in naïve rats detected at 9.4 T.
(Liu X, Yang Z, Li R, Xie J, Yin Q, Bloom AS, Li SJ)
Magn Reson Imaging
2012 Feb;30(2):261-70 PMID: 22079072 PMCID: PMC3402210 SCOPUS ID: 2-s2.0-84855481910 11/15/2011
15 Citations
Expectation modulates human brain responses to acute cocaine: a functional magnetic resonance imaging study.
(Kufahl P, Li Z, Risinger R, Rainey C, Piacentine L, Wu G, Bloom A, Yang Z, Li SJ)
Biol Psychiatry
2008 Jan 15;63(2):222-30 PMID: 17644071 SCOPUS ID: 2-s2.0-37349070329 07/24/2007
53 Citations
A validation of event-related FMRI comparisons between users of cocaine, nicotine, or cannabis and control subjects.
(Murphy K, Dixon V, LaGrave K, Kaufman J, Risinger R, Bloom A, Garavan H)
Am J Psychiatry
2006 Jul;163(7):1245-51 PMID: 16816231 SCOPUS ID: 2-s2.0-85047697140 07/04/2006
23 Citations
Peripheral blood pressure changes induced by dobutamine do not alter BOLD signals in the human brain.
(Liu H, Rainey C, Lauer KK, Piacentine L, Bloom A, Risinger R, Ward BD, Stein E, Li SJ)
Neuroimage
2006 Apr 15;30(3):745-52 PMID: 16376576 SCOPUS ID: 2-s2.0-33645751664 12/27/2005
9 Citations
Neural responses to acute cocaine administration in the human brain detected by fMRI.
(Kufahl PR, Li Z, Risinger RC, Rainey CJ, Wu G, Bloom AS, Li SJ)
Neuroimage
2005 Dec;28(4):904-14 PMID: 16061398 SCOPUS ID: 2-s2.0-28244470111 08/03/2005
126 Citations
Neural correlates of high and craving during cocaine self-administration using BOLD fMRI.
(Risinger RC, Salmeron BJ, Ross TJ, Amen SL, Sanfilipo M, Hoffmann RG, Bloom AS, Garavan H, Stein EA)
Neuroimage
2005 Jul 15;26(4):1097-108 PMID: 15886020 SCOPUS ID: 2-s2.0-20444405004 05/12/2005
185 Citations
Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli.
(Garavan H, Pankiewicz J, Bloom A, Cho JK, Sperry L, Ross TJ, Salmeron BJ, Risinger R, Kelley D, Stein EA)
Am J Psychiatry
2000 Nov;157(11):1789-98 PMID: 11058476 SCOPUS ID: 2-s2.0-0033766993 11/04/2000
832 Citations
Hepatitis C virus infection in cocaine users--a silent epidemic.
(Harsch HH, Pankiewicz J, Bloom AS, Rainey C, Cho JK, Sperry L, Stein EA)
Community Ment Health J
2000 Jun;36(3):225-33 PMID: 10933240 SCOPUS ID: 2-s2.0-0034045750 08/10/2000
29 Citations
Determination of drug-induced changes in functional MRI signal using a pharmacokinetic model.
(Bloom AS, Hoffmann RG, Fuller SA, Pankiewicz J, Harsch HH, Stein EA)
Hum Brain Mapp
1999;8(4):235-44 PMID: 10619417 PMCID: PMC6873301 SCOPUS ID: 2-s2.0-0032757698 01/05/2000
72 Citations
Practice effects on functional activation in a working memory task
(Garavan H, Kelly D, Rosen A, Bloom AS, Rao SM, Stein EA)
NeuroImage
1999;9(6 PART II) SCOPUS ID: 2-s2.0-4243660710 12/01/1999
1 Citation
Nicotine-induced limbic cortical activation in the human brain: a functional MRI study.
(Stein EA, Pankiewicz J, Harsch HH, Cho JK, Fuller SA, Hoffmann RG, Hawkins M, Rao SM, Bandettini PA, Bloom AS)
Am J Psychiatry
1998 Aug;155(8):1009-15 PMID: 9699686 SCOPUS ID: 2-s2.0-0031872333 08/12/1998
442 Citations
Between sessions reproducibility of cognitive task-induced brain activation
(Bloom AS, Wright J, Ross TJ, Rao SM, Stein EA)
NeuroImage
1998;7(4 PART II) SCOPUS ID: 2-s2.0-21944437215 01/01/1998
Brain activation by cognitive tasks: Modification by smoking cessation
(Stein EA, Bloom AS, Wright J, Pankiewicz J, Rao SM, Cho J, Harsch HH, Fuller SA, Wang Y, Watz LS)
Neuroimage
1997;5(4 PART II):S125 SCOPUS ID: 2-s2.0-21544436312 12/01/1997
Cannabinoid-induced alterations in regional cerebral blood flow in the rat.
(Bloom AS, Tershner S, Fuller SA, Stein EA)
Pharmacol Biochem Behav
1997 Aug;57(4):625-31 PMID: 9258987 SCOPUS ID: 2-s2.0-0030879417 08/01/1997
38 Citations
Nonclassical and endogenous cannabinoids: effects on the ordering of brain membranes.
(Bloom AS, Edgemond WS, Moldvan JC)
Neurochem Res
1997 May;22(5):563-8 PMID: 9131634 SCOPUS ID: 2-s2.0-0030998073 05/01/1997
36 Citations
Leukocyte hexokinase activity in aging and Alzheimer disease.
(Antuono PG, Ravanelli-Meyer J, Nicholson K, Bloom AS)
Dementia
1995;6(4):200-4 PMID: 7550599 SCOPUS ID: 2-s2.0-0029018903 07/01/1995
4 Citations
Cannabinoid-like effects of aminoalkylindole compounds on the physical properties of brain membranes: fluorescence polarization studies.
(Moldovan JC, Ward SJ, Bloom AS)
NIDA Res Monogr
1990;105:302-3 PMID: 1876019 SCOPUS ID: 2-s2.0-0025552822 01/01/1991
Interactions of flavins with melanin. Studies on equilibrium binding of riboflavin to dopa-melanin and some spectroscopic characteristics of flavin-melanin complex.
(Kozik A, Korytowski W, Sarna T, Bloom AS)
Biophys Chem
1990 Oct;38(1-2):39-48 PMID: 2128193 SCOPUS ID: 2-s2.0-0025076830 10/01/1990
15 Citations
Studies of the role of membrane lipid order in the effects of delta 9-tetrahydrocannabinol on adenylate cyclase activation in heart.
(Hillard CJ, Pounds JJ, Boyer DR, Bloom AS)
J Pharmacol Exp Ther
1990 Mar;252(3):1075-82 PMID: 2156989 SCOPUS ID: 2-s2.0-0025257436 03/01/1990
26 Citations
Cannabinoid action in the central nervous system.
(Martin B, Bloom A, Howlett A, Welch S)
NIDA Res Monogr
1988;90:275-83 PMID: 2855857 SCOPUS ID: 2-s2.0-0024164107 01/01/1988
3 Citations
Effects of pyrethroid insecticides on operant responding maintained by food.
(Stein EA, Washburn M, Walczak C, Bloom AS)
Neurotoxicol Teratol
1987;9(1):27-31 PMID: 3627076 SCOPUS ID: 2-s2.0-0023597938 01/01/1987
21 Citations
Effects of delta 9-tetrahydrocannabinol on glucagon receptor coupling to adenylate cyclase in rat liver plasma membranes.
(Hillard CJ, Bloom AS, Houslay MD)
Biochem Pharmacol
1986 Aug 15;35(16):2797-803 PMID: 3017362 SCOPUS ID: 2-s2.0-0022505707 08/15/1986
17 Citations
Effects of the cannabinoids on physical properties of brain membranes and phospholipid vesicles: fluorescence studies.
(Hillard CJ, Harris RA, Bloom AS)
J Pharmacol Exp Ther
1985 Mar;232(3):579-88 PMID: 2983062 SCOPUS ID: 2-s2.0-0021929098 03/01/1985
98 Citations
Possible noradrenergic involvement in naloxone potentiation of apomorphine-induced stereotypic climbing in mice.
(Quock RM, Bloom AS, Sadowski JA)
Pharmacol Biochem Behav
1984 Nov;21(5):733-6 PMID: 6096896 SCOPUS ID: 2-s2.0-0021689775 11/01/1984
5 Citations
The effects of delta 9-tetrahydrocannabinol on serum thyrotropin levels in the rat.
(Hillard CJ, Farber NE, Hagen TC, Bloom AS)
Pharmacol Biochem Behav
1984 Apr;20(4):547-50 PMID: 6328543 SCOPUS ID: 2-s2.0-0021344416 04/01/1984
31 Citations
The effects of cannabinoids on fluidity of brain synaptic membranes
(Hillard CJ, Harris RA, Bloom AS)
Federation Proceedings
1984;43(4) SCOPUS ID: 2-s2.0-0021137132 01/01/1984
Possible role of prostaglandins in the effects of the cannabinoids on adenylate cyclase activity.
(Hillard CJ, Bloom AS)
Eur J Pharmacol
1983 Jul 15;91(1):21-7 PMID: 6311573 SCOPUS ID: 2-s2.0-0020595620 07/15/1983
21 Citations
Pyrethroid effects on operant responding and feeding.
(Bloom AS, Staatz CG, Dieringer T)
Neurobehav Toxicol Teratol
1983;5(3):321-4 PMID: 6877472 SCOPUS ID: 2-s2.0-0020956117 05/01/1983
33 Citations
Effect of pyrethroids on [3H]kainic acid binding to mouse forebrain membranes.
(Staatz CG, Bloom AS, Lech JJ)
Toxicol Appl Pharmacol
1982 Jul;64(3):566-9 PMID: 7135402 SCOPUS ID: 2-s2.0-0020001151 07/01/1982
14 Citations
Effect of delta9-tetrahydrocannabinol on the synthesis of dopamine and norepinephrine in mouse brain synaptosomes.
(Bloom AS)
J Pharmacol Exp Ther
1982 Apr;221(1):97-103 PMID: 6278139 SCOPUS ID: 2-s2.0-0020003784 04/01/1982
39 Citations
delta 9-Tetrahydrocannabinol-induced changes in beta-adrenergic receptor binding in mouse cerebral cortex.
(Hillard CJ, Bloom AS)
Brain Res
1982 Mar 11;235(2):370-7 PMID: 6329417 SCOPUS ID: 2-s2.0-0020059703 03/11/1982
29 Citations
A pharmacological study of pyrethroid neurotoxicity in mice
(Staatz CG, Bloom AS, Lech JJ)
Pesticide Biochemistry and Physiology
June 1982;17(3):287-292 SCOPUS ID: 2-s2.0-0020323001 01/01/1982
40 Citations
Effect of intraventricular beta-endorphin and morphine on hypothalamic-pituitary-adrenal activity and the release of pituitary beta-endorphin.
(Haracz JL, Bloom AS, Wang RI, Tseng LF)
Neuroendocrinology
1981 Sep;33(3):170-5 PMID: 6270585 SCOPUS ID: 2-s2.0-0019418744 09/01/1981
62 Citations
Endogenous norepinephrine release induced by tyramine modulates intestinal ion transport.
(Tapper EJ, Bloom AS, Lewand DL)
Am J Physiol
1981 Sep;241(3):G264-9 PMID: 7282935 SCOPUS ID: 2-s2.0-0019614941 09/01/1981
30 Citations
Effects of beta-endorphin on body temperature in mice at different ambient temperatures.
(Bloom AS, Tseng LF)
Peptides
1981;2(3):293-7 PMID: 6272245 SCOPUS ID: 2-s2.0-0019818147 01/01/1981
33 Citations
Adrenalectomy reverses the effects of delta-9-THC on mouse brain 5-hydroxytryptamine turnover.
(Johnson KM, Dewey WL, Bloom AS)
Pharmacology
1981;23(4):223-9 PMID: 6275421 SCOPUS ID: 2-s2.0-0019412511 01/01/1981
5 Citations
Cannabinoid effects on the synthesis of dopamine and norepinephrine in mouse brain synaptosomes
(Bloom AS, Hardman HF)
Federation Proceedings
1981;40(3 I):248 SCOPUS ID: 2-s2.0-0019412262 01/01/1981
Interaction of ambient temperature with the effects of delta 9-tetrahydrocannabinol on brain catecholamine synthesis and plasma corticosterone levels.
(Bloom AS, Kiernan CJ)
Psychopharmacology (Berl)
1980;67(3):215-9 PMID: 6247738 SCOPUS ID: 2-s2.0-0018851676 01/01/1980
19 Citations
Effects of Δ
9
-tetrahydrocannabinol (THC) and analogs on
3
H-dihydroalprenolol (DHA) binding in mouse cerebral cortex
(Kiernan CJ, Bloom AS)
Federation Proceedings
1980;39(3 II):3071 SCOPUS ID: 2-s2.0-0018900519 01/01/1980
Effect of Δ
9
-tetrahydrocannabinol on the synthesis of dopamine and norepinephrine in striatal and brain stem synaptosomes
(Bloom AS, Nabena CD, Kiernan CJ)
Federation Proceedings
1979;38(3 I) SCOPUS ID: 2-s2.0-0018777869 01/01/1979
Effects of delta9-tetrahydrocannabinol on ATPases in mouse brain subcellular fractions.
(Bloom AS, Haavik CO, Strehlow D)
Life Sci
1978 Oct 02;23(13):1399-404 PMID: 214649 SCOPUS ID: 2-s2.0-0018196719 10/02/1978
11 Citations
A comparison of some pharmacological actions of morphine and delta9-tetrahydrocannabinol in the mouse.
(Bloom AS, Dewey WL)
Psychopharmacology (Berl)
1978 May 31;57(3):243-8 PMID: 97703 SCOPUS ID: 2-s2.0-0018154549 05/31/1978
86 Citations
The effects of cannabinoids on body temperature and brain catecholamine synthesis.
(Bloom AS, Johnson KM, Dewey WL)
Res Commun Chem Pathol Pharmacol
1978 Apr;20(1):51-7 PMID: 663408 SCOPUS ID: 2-s2.0-0018091004 04/01/1978
27 Citations
Δ
9
-Tetrahydrocannabinol (THC) induced increase in brain catecholamine synthesis and plasma corticosterone (CS) levels in the absence of hypothermia
(Bloom AS, Kiernan CJ, Haavik CO)
Federation Proceedings
1978;37(3) SCOPUS ID: 2-s2.0-17344384194 01/01/1978
Effects of d-amphetamine and strychnine on cycloheximide- and diethyldithiocarbamate-induced amnesia in mice.
(Quinton EE, Bloom AS)
J Comp Physiol Psychol
1977 Dec;91(6):1390-7 PMID: 202616 SCOPUS ID: 2-s2.0-0017612606 12/01/1977
19 Citations
Effects of cycloheximide, diethyldithiocarbamate and D-amphetamine on protein and catecholamine biosynthesis in mouse brain.
(Bloom AS, Quinton EE, Carr LA)
Neuropharmacology
1977 Jun;16(6):411-8 PMID: 198698 SCOPUS ID: 2-s2.0-0017414657 06/01/1977
18 Citations
9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine.
(Bloom AS, Dewey WL, Harris LS, Brosius KK)
J Pharmacol Exp Ther
1977 Feb;200(2):263-70 PMID: 839438 SCOPUS ID: 2-s2.0-0017367697 02/01/1977
58 Citations
Effect of Δ
9
-tetrahydrocannabinol (THC) in vitro on ATPases in mouse brain subcellular fractions
(Bloom AS, Haavik CO, Hardman HF)
Federation Proceedings
1977;36(3) SCOPUS ID: 2-s2.0-18144438742 01/01/1977
1 Citation
The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain catecholamines.
(Bloom AS, Dewey WL, Harris LS, Brosius KK)
J Pharmacol Exp Ther
1976 Jul;198(1):33-41 PMID: 6793 SCOPUS ID: 2-s2.0-0017078077 07/01/1976
33 Citations
Interactions of active constituents of marihuana with other drugs in the neuron.
(Dewey WL, Johnson KM, Bloom AS)
Ann N Y Acad Sci
1976;281:190-7 PMID: 798522 SCOPUS ID: 2-s2.0-0017096884 01/01/1976
3 Citations
Development of central catecholamine systems in the postnatal rat brain
(Schumann AM, Bloom AS, Dewey WL, Klase PA)
Pharmacologist
1976;18(2) SCOPUS ID: 2-s2.0-17944403974 01/01/1976
Correlation between the effects of several cannabinoids on catecholamine synthesis, body temperature, and behavior
(Bloom AS, Johnson KM, Bowman FJ, Dewey WL)
Federation Proceedings
1976;35(3) SCOPUS ID: 2-s2.0-0017260730 01/01/1976
3 Citations
The effects of analgesics, narcotic antagonist analgesics and narcotic antagonists on the activation of CNS catecholamine containing neurons in mice
(Bloom A, Brosius K)
Federation Proceedings
1975;34(3) SCOPUS ID: 2-s2.0-0016608425 01/01/1975
1 Citation
Inhibition of brain protein and norepinephrine synthesis by diethyldithiocarbamate (DDC): possible mechanisms for amnesic effects
(Carr LA, Bloom AS, Quinton EE)
Pharmacologist
1974;16(2) SCOPUS ID: 2-s2.0-0016302341 01/01/1974
Last update: 07/02/2021