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Medical College of Wisconsin

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Allen W. Cowley PhD

Professor

Institution: Medical College of Wisconsin
Department: Physiology

Member of the Cardiovascular Research Center

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Publications (382)

NADPH Oxidase 4 and Metabolic Stress in Dahl Salt-Sensitive Rat Kidneys. (Shimada S, Yang C, Hoffmann BR, Stodola TJ, Kurth T, Liang M, Dash RK, Cowley AW Jr) Hypertension 2026 Mar;83(3):e25718 PMID: 41368709 12/10/2025

Connecting genes to physiology: the first 25 years of Physiological Genomics. (Joe B, Cowley AW Jr, Garrett MR, Kriegel AJ, Prokop JW, Lee EC, Akinola OM, Coller HA) Physiol Genomics 2025 Dec 01;57(12):700-719 PMID: 41159925 SCOPUS ID: 2-s2.0-105024018960 10/29/2025

Null mutation of the p67phox subunit of NOX2 permits compensatory changes in renal blood flow during the development of salt-sensitive hypertension in SS rats. (Evans LC, Dayton A, Kurth T, Anidu BS, Polichnowski AJ, Cowley AW Jr) Am J Physiol Renal Physiol 2025 Nov 01;329(5):F745-F751 PMID: 41115068 PMCID: PMC12622236 SCOPUS ID: 2-s2.0-105021328055 10/20/2025

Sex dimorphism and substrate dependency of liver mitochondrial bioenergetics and H₂O₂ production. (Dave DD, Taheri P, Boovarahan SR, Kim J, Cowley AW Jr, Audi SH, Dash RK) Am J Physiol Gastrointest Liver Physiol 2025 Dec 01;329(6):G664-G679 PMID: 41106842 PMCID: PMC12739962 SCOPUS ID: 2-s2.0-105022779068 10/18/2025

Sex Differences in Renal Mitochondrial Respiration and H2O2 Emission in Young Dahl Salt-Sensitive Rats. (Yang C, Dave DD, Boovarahan SR, Shimada S, Geurts A, Dash RK, Cowley AW Jr) Function (Oxf) 2025 Oct 28;6(6) PMID: 41055389 PMCID: PMC12560232 SCOPUS ID: 2-s2.0-105020316608 10/07/2025 2 Citations

Chromatin interaction maps of human arterioles reveal mechanisms for the genetic regulation of blood pressure. (Liu Y, Pandey R, Qiu Q, Liu P, Xue H, Wang J, Therani B, Ying R, Usa K, Grzybowski M, Yang C, Mishra MK, Greene AS, Cowley AW Jr, Rao S, Geurts AM, Widlansky ME, Liang M) Nat Commun 2025 Jul 17;16(1):6577 PMID: 40675959 PMCID: PMC12271514 SCOPUS ID: 2-s2.0-105011067559 07/18/2025 1 Citation

Physiological role and mechanisms of action for a long noncoding haplotype region. (Xue H, Mishra MK, Liu Y, Liu P, Grzybowski M, Pandey R, Usa K, Vanden Avond MA, Bala N, Alli AA, Cowley AW Jr, Qiu Q, Greene AS, Rao S, O'Meara CC, Geurts AM, Liang M) Cell Rep 2025 Jun 24;44(6):115805 PMID: 40493452 PMCID: PMC12263090 SCOPUS ID: 2-s2.0-105007437771 06/10/2025 1 Citation

Chromatin State Maps of Blood Pressure-Relevant Renal Segments Reveal Potential Regulatory Role for SNPs. (Ray A, Yang C, Stelloh C, Tutaj M, Liu P, Liu Y, Qiu Q, Auer PL, Lin CW, Widlansky ME, Geurts AM, Cowley AW Jr, Liang M, Kwitek AE, Greene AS, Rao S) Hypertension 2025 Mar;82(3):476-488 PMID: 39723540 PMCID: PMC12236357 SCOPUS ID: 2-s2.0-85213707759 12/26/2024

Chromatin interaction maps of human arterioles reveal new mechanisms for the genetic regulation of blood pressure. (Liu Y, Pandey R, Qiu Q, Liu P, Xue H, Wang J, Therani B, Ying R, Usa K, Grzybowski M, Yang C, Mishra MK, Greene AS, Cowley AW Jr, Rao S, Geurts AM, Widlansky ME, Liang M) bioRxiv 2024 Oct 14 PMID: 39463975 PMCID: PMC11507733 10/28/2024

Renal Medulla in Hypertension. (Cowley AW Jr, Roman RJ, Mattson DL, Franchini KG, O'Connor PM, Makino A, Taylor NE, Evans LC, Mori T, Dickhout JG, Jin C, Miyata N, Nakanishi K, Szentiványi M Jr, Park F, Skelton MM, Kurth T, Shimada S) Hypertension 2024 Dec;81(12):2383-2394 PMID: 39344517 PMCID: PMC11578791 SCOPUS ID: 2-s2.0-85206462624 09/30/2024 4 Citations

Inhibition of mTORC2 promotes natriuresis in Dahl salt-sensitive rats via the decrease of NCC and ENaC activity. (Yang C, Isaeva E, Shimada S, Kurth T, Stumpf M, Zheleznova NN, Staruschenko A, Dash RK, Cowley AW Jr) Am J Physiol Renal Physiol 2024 Sep 01;327(3):F435-F449 PMID: 38779754 PMCID: PMC11460535 SCOPUS ID: 2-s2.0-85201902774 05/23/2024 3 Citations

Histone Modifications and Their Contributions to Hypertension. (Ray A, Stelloh C, Liu Y, Meyer A, Geurts AM, Cowley AW Jr, Greene AS, Liang M, Rao S) Hypertension 2024 Feb;81(2):229-239 PMID: 38031837 PMCID: PMC11229175 SCOPUS ID: 2-s2.0-85182776843 11/30/2023 11 Citations

Metabolic Responses of Normal Rat Kidneys to a High Salt Intake. (Shimada S, Hoffmann BR, Yang C, Kurth T, Greene AS, Liang M, Dash RK, Cowley AW Jr) Function (Oxf) 2023;4(5):zqad031 PMID: 37575482 PMCID: PMC10413938 SCOPUS ID: 2-s2.0-85168069622 08/14/2023 11 Citations

Computational Modeling of Substrate-Dependent Mitochondrial Respiration and Bioenergetics in the Heart and Kidney Cortex and Outer Medulla. (Sadri S, Zhang X, Audi SH, Cowley AW Jr, Dash RK) Function (Oxf) 2023;4(5):zqad038 PMID: 37575476 PMCID: PMC10413947 SCOPUS ID: 2-s2.0-85168064544 08/14/2023 5 Citations

Effects of ROS pathway inhibitors and NADH and FADH₂ linked substrates on mitochondrial bioenergetics and ROS emission in the heart and kidney cortex and outer medulla. (Sadri S, Tomar N, Yang C, Audi SH, Cowley AW Jr, Dash RK) Arch Biochem Biophys 2023 Aug;744:109690 PMID: 37429534 PMCID: PMC10528392 SCOPUS ID: 2-s2.0-85165963858 07/11/2023 15 Citations

Robustness of single-cell RNA-seq for identifying differentially expressed genes. (Liu Y, Huang J, Pandey R, Liu P, Therani B, Qiu Q, Rao S, Geurts AM, Cowley AW Jr, Greene AS, Liang M) BMC Genomics 2023 Jul 03;24(1):371 PMID: 37394518 PMCID: PMC10316566 SCOPUS ID: 2-s2.0-85163598768 07/03/2023 11 Citations

Advancing Physiology with Expanded Multi-Omics. (Liang M, Cowley AW Jr, Greene AS, Geurts AM, Liu P, Liu Y, Rao S) Function (Oxf) 2022;3(4):zqac031 PMID: 35801086 PMCID: PMC9247404 SCOPUS ID: 2-s2.0-85140379715 07/09/2022 3 Citations

Recently released report by The National Academies of Sciences, Engineering, and Medicine proposes significant changes in understanding and managing temporomandibular disorders. (Greene CS, Kusiak JW, Cowley T, Cowley AW Jr) J Prosthet Dent 2022 Nov;128(5):845-846 PMID: 35491258 SCOPUS ID: 2-s2.0-85130052273 05/02/2022 4 Citations

Assuring the Future of Basic Biomedical Science. (Cowley AW Jr) Function (Oxf) 2022;3(2):zqac006 PMID: 35399492 PMCID: PMC8991019 SCOPUS ID: 2-s2.0-85140227576 04/12/2022

Acute Increase of Renal Perfusion Pressure Causes Rapid Activation of mTORC1 (Mechanistic Target Of Rapamycin Complex 1) and Leukocyte Infiltration. (Shimada S, Yang C, Kumar V, Mattson DL, Cowley AW Jr) Hypertension 2022 Jun;79(6):1180-1189 PMID: 35291809 PMCID: PMC9098670 SCOPUS ID: 2-s2.0-85129999498 03/17/2022 7 Citations

Divergent roles of angiotensin II upon the immediate and sustained increases of renal blood flow following unilateral nephrectomy. (Shimada S, Yang C, Kurth T, Cowley AW Jr) Am J Physiol Renal Physiol 2022 May 01;322(5):F473-F485 PMID: 35224992 PMCID: PMC8977133 SCOPUS ID: 2-s2.0-85128161119 03/01/2022 9 Citations

Long-Term Continuous Measurement of Renal Blood Flow in Conscious Rats. (Shimada S, Cowley AW Jr) J Vis Exp 2022 Feb 08(180) PMID: 35225288 SCOPUS ID: 2-s2.0-85125412565 03/01/2022 2 Citations

Substrate- and Calcium-Dependent Differential Regulation of Mitochondrial Oxidative Phosphorylation and Energy Production in the Heart and Kidney. (Zhang X, Tomar N, Kandel SM, Audi SH, Cowley AW Jr, Dash RK) Cells 2021 Dec 31;11(1) PMID: 35011693 PMCID: PMC8750792 SCOPUS ID: 2-s2.0-85122006134 01/12/2022 14 Citations

Unique Associations of DNA Methylation Regions With 24-Hour Blood Pressure Phenotypes in Black Participants. (Roberts ML, Kotchen TA, Pan X, Li Y, Yang C, Liu P, Wang T, Laud PW, Chelius TH, Munyura Y, Mattson DL, Liu Y, Cowley AW Jr, Kidambi S, Liang M) Hypertension 2022 Apr;79(4):761-772 PMID: 34994206 PMCID: PMC8917053 SCOPUS ID: 2-s2.0-85126152389 01/08/2022 22 Citations

Substrate-dependent differential regulation of mitochondrial bioenergetics in the heart and kidney cortex and outer medulla. (Tomar N, Zhang X, Kandel SM, Sadri S, Yang C, Liang M, Audi SH, Cowley AW Jr, Dash RK) Biochim Biophys Acta Bioenerg 2022 Feb 01;1863(2):148518 PMID: 34864090 PMCID: PMC8957717 SCOPUS ID: 2-s2.0-85120828118 12/06/2021 25 Citations

Theodore Allen Kotchen, MD: June 27, 1938-July 6, 2021. (Cowley AW Jr, Kidambi S, Liang M, Grim C, Hamet P) Hypertension 2021 Dec;78(6):1674-1676 PMID: 34719936 SCOPUS ID: 2-s2.0-85121955751 11/02/2021

Global identification and characterization of tRNA-derived RNA fragment landscapes across human cancers. (Sun X, Yang J, Yu M, Yao D, Zhou L, Li X, Qiu Q, Lin W, Lu B, Chen E, Wang P, Chen W, Tao S, Xu H, Williams A, Liu Y, Pan X, Cowley AW Jr, Lu W, Liang M, Liu P, Lu Y) NAR Cancer 2020 Dec;2(4):zcaa031 PMID: 34316691 PMCID: PMC8210304 SCOPUS ID: 2-s2.0-85104342899 07/29/2021 23 Citations

Recently Released Report by Major Scientific Academy Proposes Significant Changes in Understanding and Managing Temporomandibular Disorders. (Greene CS, Kusiak JW, Cowley T, Cowley AW Jr) J Oral Maxillofac Surg 2022 Jan;80(1):8-9 PMID: 34252367 SCOPUS ID: 2-s2.0-85112571063 07/13/2021 9 Citations

Dietary Sodium Restriction Results in Tissue-Specific Changes in DNA Methylation in Humans. (Kidambi S, Pan X, Yang C, Liu P, Roberts ML, Li Y, Wang T, Laud PW, Liu Y, Rubens M, Thomas R, Widlansky ME, Beyer AM, Liu Y, Cowley AW Jr, Kotchen TA, Munyura Y, Moosreiner A, Mattson DL, Liang M) Hypertension 2021 Aug;78(2):434-446 PMID: 34120454 PMCID: PMC9299531 SCOPUS ID: 2-s2.0-85109563974 06/15/2021 16 Citations

Thomas George Coleman, PhD (1940-2021). (Hall JE, Navar LG, Cowley AW Jr, Summers RL, Hester RL) Hypertension 2021 Jun;77(6):1800-1803 PMID: 33934621 SCOPUS ID: 2-s2.0-85106545374 05/04/2021

Hydrogen peroxide (H₂O₂) mediated activation of mTORC2 increases intracellular Na⁺ concentration in the renal medullary thick ascending limb of Henle. (Zheleznova NN, Kumar V, Kurth T, Cowley AW Jr) Sci Rep 2021 Mar 31;11(1):7300 PMID: 33790341 PMCID: PMC8012714 SCOPUS ID: 2-s2.0-85103745861 04/02/2021 4 Citations

Computational/Experimental Interrogation of the Failing Heart-A Perspective on "Impaired Myocardial Energetics Causes Mechanical Dysfunction in Decompensated Failing Hearts". (Cowley AW Jr, Dash RK) Function (Oxf) 2020;1(2):zqaa022 PMID: 35330639 PMCID: PMC8788834 SCOPUS ID: 2-s2.0-85140267236 10/09/2020

A Journalistic Break Through. (Cowley AW Jr) Function (Oxf) 2020;1(2):zqaa023 PMID: 35330640 PMCID: PMC8788785 SCOPUS ID: 2-s2.0-85106106769 10/05/2020 1 Citation

NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease. (Pavlov TS, Palygin O, Isaeva E, Levchenko V, Khedr S, Blass G, Ilatovskaya DV, Cowley AW Jr, Staruschenko A) FASEB J 2020 Oct;34(10):13396-13408 PMID: 32799394 PMCID: PMC7722042 SCOPUS ID: 2-s2.0-85089380202 08/18/2020 31 Citations

Renal Perfusion Pressure Determines Infiltration of Leukocytes in the Kidney of Rats With Angiotensin II-Induced Hypertension. (Shimada S, Abais-Battad JM, Alsheikh AJ, Yang C, Stumpf M, Kurth T, Mattson DL, Cowley AW Jr) Hypertension 2020 Sep;76(3):849-858 PMID: 32755400 PMCID: PMC7429333 SCOPUS ID: 2-s2.0-85089415483 08/07/2020 16 Citations

Twenty-four-hour versus clinic blood pressure levels as predictors of long-term cardiovascular and renal disease outcomes among African Americans. (Kidambi S, Wang T, Chelius T, Nunuk I, Agarwal P, Laud P, Mattson D, Cowley AW Jr, Liang M, Kotchen T) Sci Rep 2020 Jul 15;10(1):11685 PMID: 32669581 PMCID: PMC7363933 SCOPUS ID: 2-s2.0-85087974638 07/17/2020 6 Citations

NOX4/H₂O₂/mTORC1 Pathway in Salt-Induced Hypertension and Kidney Injury. (Kumar V, Kurth T, Zheleznova NN, Yang C, Cowley AW Jr) Hypertension 2020 Jul;76(1):133-143 PMID: 32475313 PMCID: PMC10629473 SCOPUS ID: 2-s2.0-85086346307 06/02/2020 34 Citations

The early effects of uninephrectomy on rat kidney metabolic state using optical imaging. (Mehrvar S, Foomani FH, Shimada S, Yang C, Zheleznova NN, Mostaghimi S, Cowley AW Jr, Ranji M) J Biophotonics 2020 Sep;13(9):e202000089 PMID: 32436651 SCOPUS ID: 2-s2.0-85087216557 05/22/2020 7 Citations

Chromosomal Substitution Strategies to Localize Genomic Regions Related to Complex Traits. (Cowley AW Jr, Dwinell MR) Compr Physiol 2020 Mar 12;10(2):365-388 PMID: 32163204 SCOPUS ID: 2-s2.0-85081890516 03/13/2020 7 Citations

CCL2 mediates early renal leukocyte infiltration during salt-sensitive hypertension. (Alsheikh AJ, Dasinger JH, Abais-Battad JM, Fehrenbach DJ, Yang C, Cowley AW Jr, Mattson DL) Am J Physiol Renal Physiol 2020 Apr 01;318(4):F982-F993 PMID: 32150444 PMCID: PMC7191447 SCOPUS ID: 2-s2.0-85083041128 03/10/2020 26 Citations

Temporal Expression and Cellular Localization of PAPPA2 in the Developing Kidney of Rat. (Kumar V, Yang C, Cowley AW Jr) J Histochem Cytochem 2020 Mar;68(3):209-222 PMID: 31989854 PMCID: PMC7045303 SCOPUS ID: 2-s2.0-85078414057 01/29/2020 3 Citations

Epigenetic Modifications in T Cells: The Role of DNA Methylation in Salt-Sensitive Hypertension. (Dasinger JH, Alsheikh AJ, Abais-Battad JM, Pan X, Fehrenbach DJ, Lund H, Roberts ML, Cowley AW Jr, Kidambi S, Kotchen TA, Liu P, Liang M, Mattson DL) Hypertension 2020 Feb;75(2):372-382 PMID: 31838911 PMCID: PMC7058976 SCOPUS ID: 2-s2.0-85077761000 12/17/2019 33 Citations

NOX2-derived reactive oxygen species in immune cells exacerbates salt-sensitive hypertension. (Abais-Battad JM, Lund H, Dasinger JH, Fehrenbach DJ, Cowley AW Jr, Mattson DL) Free Radic Biol Med 2020 Jan;146:333-339 PMID: 31730933 PMCID: PMC6942201 SCOPUS ID: 2-s2.0-85076232983 11/16/2019 29 Citations

Progression of diabetic kidney disease in T2DN rats. (Palygin O, Spires D, Levchenko V, Bohovyk R, Fedoriuk M, Klemens CA, Sykes O, Bukowy JD, Cowley AW Jr, Lazar J, Ilatovskaya DV, Staruschenko A) Am J Physiol Renal Physiol 2019 Dec 01;317(6):F1450-F1461 PMID: 31566426 PMCID: PMC6960784 SCOPUS ID: 2-s2.0-85075960951 10/01/2019 52 Citations

Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome. (Abais-Battad JM, Alsheikh AJ, Pan X, Fehrenbach DJ, Dasinger JH, Lund H, Roberts ML, Kriegel AJ, Cowley AW Jr, Kidambi S, Kotchen TA, Liu P, Liang M, Mattson DL) Hypertension 2019 Oct;74(4):854-863 PMID: 31476910 PMCID: PMC6739138 SCOPUS ID: 2-s2.0-85072134357 09/04/2019 42 Citations

Voltage gated proton channels modulate mitochondrial reactive oxygen species production by complex I in renal medullary thick ascending limb. (Patel B, Zheleznova NN, Ray SC, Sun J, Cowley AW Jr, O'Connor PM) Redox Biol 2019 Oct;27:101191 PMID: 31060879 PMCID: PMC6859587 SCOPUS ID: 2-s2.0-85064987982 05/08/2019 13 Citations

A thermodynamically-constrained mathematical model for the kinetics and regulation of NADPH oxidase 2 complex-mediated electron transfer and superoxide production. (Tomar N, Sadri S, Cowley AW Jr, Yang C, Quryshi N, Pannala VR, Audi SH, Dash RK) Free Radic Biol Med 2019 Apr;134:581-597 PMID: 30769160 PMCID: PMC6588456 SCOPUS ID: 2-s2.0-85061529596 02/16/2019 17 Citations

Therapeutic Suppression of mTOR (Mammalian Target of Rapamycin) Signaling Prevents and Reverses Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats. (Kumar V, Evans LC, Kurth T, Yang C, Wollner C, Nasci V, Zheleznova NN, Bukowy J, Dayton A, Cowley AW Jr) Hypertension 2019 Mar;73(3):630-639 PMID: 30595123 PMCID: PMC6374175 SCOPUS ID: 2-s2.0-85061496964 01/01/2019 45 Citations

Chrm3 Gene and M3 Muscarinic Receptors Contribute to Salt-Sensitive Hypertension. (Cowley AW Jr) Hypertension 2018 Sep;72(3):588-591 PMID: 30354773 PMCID: PMC6205740 SCOPUS ID: 2-s2.0-85055600181 10/26/2018 13 Citations

Do computers dream of electric glomeruli? (Bukowy JD, Dayton A, Cloutier D, Lombard JH, Solberg Woods LC, Beard DA, Cowley AW Jr) Kidney Int 2018 Sep;94(3):635 PMID: 30143073 PMCID: PMC6110099 SCOPUS ID: 2-s2.0-85051364346 08/26/2018

Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections. (Bukowy JD, Dayton A, Cloutier D, Manis AD, Staruschenko A, Lombard JH, Solberg Woods LC, Beard DA, Cowley AW Jr) J Am Soc Nephrol 2018 Aug;29(8):2081-2088 PMID: 29921718 PMCID: PMC6065078 SCOPUS ID: 2-s2.0-85050939134 06/21/2018 103 Citations

A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease. (Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW Jr, Birnbaumer L, Staruschenko A) J Am Soc Nephrol 2018 Jul;29(7):1917-1927 PMID: 29793963 PMCID: PMC6050934 SCOPUS ID: 2-s2.0-85049383067 05/26/2018 125 Citations

Stability of global methylation profiles of whole blood and extracted DNA under different storage durations and conditions. (Li Y, Pan X, Roberts ML, Liu P, Kotchen TA, Cowley AW Jr, Mattson DL, Liu Y, Liang M, Kidambi S) Epigenomics 2018 Jun;10(6):797-811 PMID: 29683333 SCOPUS ID: 2-s2.0-85049644277 04/24/2018 45 Citations

Transcriptomic analysis reveals inflammatory and metabolic pathways that are regulated by renal perfusion pressure in the outer medulla of Dahl-S rats. (Evans LC, Dayton A, Yang C, Liu P, Kurth T, Ahn KW, Komas S, Stingo FC, Laud PW, Vannucci M, Liang M, Cowley AW Jr) Physiol Genomics 2018 Jun 01;50(6):440-447 PMID: 29602296 PMCID: PMC6032288 SCOPUS ID: 2-s2.0-85051123417 04/01/2018 13 Citations

A comprehensive evaluation of alignment software for reduced representation bisulfite sequencing data. (Sun X, Han Y, Zhou L, Chen E, Lu B, Liu Y, Pan X, Cowley AW Jr, Liang M, Wu Q, Lu Y, Liu P) Bioinformatics 2018 Aug 15;34(16):2715-2723 PMID: 29579198 SCOPUS ID: 2-s2.0-85055129630 03/27/2018 34 Citations

Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure. (Palygin O, Evans LC, Cowley AW Jr, Staruschenko A) J Am Heart Assoc 2017 Sep 12;6(9) PMID: 28899893 PMCID: PMC5634305 SCOPUS ID: 2-s2.0-85029770347 09/14/2017 25 Citations

Inhibition of Mammalian Target of Rapamycin Complex 1 Attenuates Salt-Induced Hypertension and Kidney Injury in Dahl Salt-Sensitive Rats. (Kumar V, Wollner C, Kurth T, Bukowy JD, Cowley AW Jr) Hypertension 2017 Oct;70(4):813-821 PMID: 28827472 PMCID: PMC5599353 SCOPUS ID: 2-s2.0-85030612213 08/23/2017 43 Citations

How can precision medicine be applied to temporomandibular disorders and its comorbidities? (Wilentz JB, Cowley AW Jr) Mol Pain 2017;13:1744806917710094 PMID: 28741410 PMCID: PMC5533261 SCOPUS ID: 2-s2.0-85039074884 07/26/2017 12 Citations

Increased Perfusion Pressure Drives Renal T-Cell Infiltration in the Dahl Salt-Sensitive Rat. (Evans LC, Petrova G, Kurth T, Yang C, Bukowy JD, Mattson DL, Cowley AW Jr) Hypertension 2017 Sep;70(3):543-551 PMID: 28696224 PMCID: PMC5589123 SCOPUS ID: 2-s2.0-85023160842 07/12/2017 64 Citations

Renal Delivery of Anti-microRNA Oligonucleotides in Rats. (Usa KS, Liu Y, Kurth T, Kriegel AJ, Mattson DL, Cowley AW Jr, Liang M) Methods Mol Biol 2017;1527:409-419 PMID: 28116733 SCOPUS ID: 2-s2.0-85011003449 01/25/2017

Breaking the Cycle: Estrous Variation Does Not Require Increased Sample Size in the Study of Female Rats. (Dayton A, Exner EC, Bukowy JD, Stodola TJ, Kurth T, Skelton M, Greene AS, Cowley AW Jr) Hypertension 2016 Nov;68(5):1139-1144 PMID: 27672030 PMCID: PMC5104284 SCOPUS ID: 2-s2.0-84988699090 09/28/2016 53 Citations

Role of Nox4 and p67phox subunit of Nox2 in ROS production in response to increased tubular flow in the mTAL of Dahl salt-sensitive rats. (Zheleznova NN, Yang C, Cowley AW Jr) Am J Physiol Renal Physiol 2016 Aug 01;311(2):F450-8 PMID: 27279484 PMCID: PMC5243222 SCOPUS ID: 2-s2.0-84984629818 06/10/2016 32 Citations

p66Shc regulates renal vascular tone in hypertension-induced nephropathy. (Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW Jr, Geurts AM, Staruschenko A, Imig JD, Sorokin A) J Clin Invest 2016 Jul 01;126(7):2533-46 PMID: 27270176 PMCID: PMC4922697 SCOPUS ID: 2-s2.0-84978419542 06/09/2016 41 Citations

Introduction to the American Heart Association's Hypertension Strategically Focused Research Network. (Muntner P, Becker RC, Calhoun D, Chen D, Cowley AW Jr, Flynn JT, Grobe JL, Kidambi S, Kotchen TA, Lackland DT, Leslie KK, Li Y, Liang M, Lloyd A, Mattson DL, Mendizabal B, Mitsnefes M, Nair A, Pierce GL, Pollock JS, Safford MM, Santillan MK, Sigmund CD, Thomas SJ, Urbina EM) Hypertension 2016 Apr;67(4):674-80 PMID: 26902490 PMCID: PMC5135412 SCOPUS ID: 2-s2.0-84960812805 02/24/2016 7 Citations

Ushering Hypertension Into a New Era of Precision Medicine. (Kotchen TA, Cowley AW Jr, Liang M) JAMA 2016 Jan 26;315(4):343-4 PMID: 26769233 PMCID: PMC5238956 SCOPUS ID: 2-s2.0-84964308652 01/16/2016 73 Citations

Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. (Cowley AW Jr, Yang C, Zheleznova NN, Staruschenko A, Kurth T, Rein L, Kumar V, Sadovnikov K, Dayton A, Hoffman M, Ryan RP, Skelton MM, Salehpour F, Ranji M, Geurts A) Hypertension 2016 Feb;67(2):440-50 PMID: 26644237 PMCID: PMC4713301 SCOPUS ID: 2-s2.0-84954403695 12/09/2015 94 Citations

Pappa2 is linked to salt-sensitive hypertension in Dahl S rats. (Cowley AW Jr, Yang C, Kumar V, Lazar J, Jacob H, Geurts AM, Liu P, Dayton A, Kurth T, Liang M) Physiol Genomics 2016 Jan;48(1):62-72 PMID: 26534937 PMCID: PMC4757026 SCOPUS ID: 2-s2.0-84953280775 11/05/2015 33 Citations

Use of Enzymatic Biosensors to Quantify Endogenous ATP or H2O2 in the Kidney. (Palygin O, Levchenko V, Evans LC, Blass G, Cowley AW Jr, Staruschenko A) J Vis Exp 2015 Oct 12(104) PMID: 26485400 PMCID: PMC4684070 SCOPUS ID: 2-s2.0-84946430783 10/21/2015 16 Citations

Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes. (Kriegel AJ, Baker MA, Liu Y, Liu P, Cowley AW Jr, Liang M) Hypertension 2015 Oct;66(4):793-9 PMID: 26283043 PMCID: PMC4567475 SCOPUS ID: 2-s2.0-84941199042 08/19/2015 96 Citations

deGPS is a powerful tool for detecting differential expression in RNA-sequencing studies. (Chu C, Fang Z, Hua X, Yang Y, Chen E, Cowley AW Jr, Liang M, Liu P, Lu Y) BMC Genomics 2015 Jun 13;16(1):455 PMID: 26070955 PMCID: PMC4465298 SCOPUS ID: 2-s2.0-84931273060 06/14/2015 16 Citations

Effects of p67phox on the mitochondrial oxidative state in the kidney of Dahl salt-sensitive rats: optical fluorescence 3-D cryoimaging. (Salehpour F, Ghanian Z, Yang C, Zheleznova NN, Kurth T, Dash RK, Cowley AW Jr, Ranji M) Am J Physiol Renal Physiol 2015 Aug 15;309(4):F377-82 PMID: 26062875 PMCID: PMC4596732 SCOPUS ID: 2-s2.0-84939495664 06/13/2015 17 Citations

Genetic, epigenetic, and mechanistic studies of temporomandibular disorders and overlapping pain conditions. (Munzenmaier DH, Wilentz J, Cowley AW Jr) Mol Pain 2014 Dec 15;10:72 PMID: 25511046 PMCID: PMC4269918 SCOPUS ID: 2-s2.0-84925212033 12/17/2014 12 Citations

Null mutation of the nicotinamide adenine dinucleotide phosphate-oxidase subunit p67phox protects the Dahl-S rat from salt-induced reductions in medullary blood flow and glomerular filtration rate. (Evans LC, Ryan RP, Broadway E, Skelton MM, Kurth T, Cowley AW Jr) Hypertension 2015 Mar;65(3):561-8 PMID: 25489057 PMCID: PMC4326559 SCOPUS ID: 2-s2.0-84924233263 12/10/2014 30 Citations

Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats. (Geurts AM, Mattson DL, Liu P, Cabacungan E, Skelton MM, Kurth TM, Yang C, Endres BT, Klotz J, Liang M, Cowley AW Jr) Hypertension 2015 Feb;65(2):447-55 PMID: 25452472 PMCID: PMC4289102 SCOPUS ID: 2-s2.0-84921562280 12/03/2014 62 Citations

Characteristics of long non-coding RNAs in the Brown Norway rat and alterations in the Dahl salt-sensitive rat. (Wang F, Li L, Xu H, Liu Y, Yang C, Cowley AW Jr, Wang N, Liu P, Liang M) Sci Rep 2014 Nov 21;4:7146 PMID: 25413633 PMCID: PMC4894415 SCOPUS ID: 2-s2.0-84923342198 11/22/2014 53 Citations

Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertension. (Cowley AW Jr, Abe M, Mori T, O'Connor PM, Ohsaki Y, Zheleznova NN) Am J Physiol Renal Physiol 2015 Feb 01;308(3):F179-97 PMID: 25354941 PMCID: PMC4312962 SCOPUS ID: 2-s2.0-84922264751 10/31/2014 94 Citations

Improved rat genome gene prediction by integration of ESTs with RNA-Seq information. (Li L, Chen E, Yang C, Zhu J, Jayaraman P, De Pons J, Kaczorowski CC, Jacob HJ, Greene AS, Hodges MR, Cowley AW Jr, Liang M, Xu H, Liu P, Lu Y) Bioinformatics 2015 Jan 01;31(1):25-32 PMID: 25217576 PMCID: PMC4296142 SCOPUS ID: 2-s2.0-84922366358 09/14/2014 6 Citations

Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats. (Cowley AW Jr, Moreno C, Jacob HJ, Peterson CB, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Reddy P, Lazar J, Evans L, Yang C, Kurth T, Liang M) Physiol Genomics 2014 Jun 01;46(11):398-410 PMID: 24714719 PMCID: PMC4042181 SCOPUS ID: 2-s2.0-84901718506 04/10/2014 18 Citations

Ultrastructure of mitochondria and the endoplasmic reticulum in renal tubules of Dahl salt-sensitive rats. (He X, Liu Y, Usa K, Tian Z, Cowley AW Jr, Liang M) Am J Physiol Renal Physiol 2014 May 15;306(10):F1190-7 PMID: 24694587 PMCID: PMC4024733 SCOPUS ID: 2-s2.0-84900812680 04/04/2014 23 Citations

Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence. (Liu Y, Liu P, Yang C, Cowley AW Jr, Liang M) Hypertension 2014 Apr;63(4):827-38 PMID: 24420542 PMCID: PMC4315612 SCOPUS ID: 2-s2.0-84897061863 01/15/2014 67 Citations

Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats. (Menzies RI, Unwin RJ, Dash RK, Beard DA, Cowley AW Jr, Carlson BE, Mullins JJ, Bailey MA) Front Physiol 2013;4:305 PMID: 24187541 PMCID: PMC3807716 11/05/2013

Aldosterone secretagogues increase adrenal blood flow in male rats. (Ansurudeen I, Kopf PG, Gauthier KM, Bornstein SR, Cowley AW Jr, Campbell WB) Endocrinology 2014 Jan;155(1):127-32 PMID: 24169551 PMCID: PMC3868807 SCOPUS ID: 2-s2.0-84891435800 10/31/2013 11 Citations

Epigenomics of hypertension. (Liang M, Cowley AW Jr, Mattson DL, Kotchen TA, Liu Y) Semin Nephrol 2013 Jul;33(4):392-9 PMID: 24011581 PMCID: PMC3777799 SCOPUS ID: 2-s2.0-84883497015 09/10/2013 70 Citations

CTGF a tubular twist on an old theme. (Cowley AW Jr) Hypertension 2013 Oct;62(4):687-8 PMID: 23959551 SCOPUS ID: 2-s2.0-84891523110 08/21/2013 1 Citation

Salt in health and disease--a delicate balance. (Kotchen TA, Cowley AW Jr, Frohlich ED) N Engl J Med 2013 Jun 27;368(26):2531-2 PMID: 23802533 SCOPUS ID: 2-s2.0-84879365020 06/28/2013 13 Citations

Progression of glomerular filtration rate reduction determined in conscious Dahl salt-sensitive hypertensive rats. (Cowley AW Jr, Ryan RP, Kurth T, Skelton MM, Schock-Kusch D, Gretz N) Hypertension 2013 Jul;62(1):85-90 PMID: 23630946 PMCID: PMC3806646 SCOPUS ID: 2-s2.0-84880725385 05/01/2013 63 Citations

Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. (Pavlov TS, Levchenko V, O'Connor PM, Ilatovskaya DV, Palygin O, Mori T, Mattson DL, Sorokin A, Lombard JH, Cowley AW Jr, Staruschenko A) J Am Soc Nephrol 2013 Jun;24(7):1053-62 PMID: 23599382 PMCID: PMC3699826 SCOPUS ID: 2-s2.0-84879580245 04/20/2013 72 Citations

Real-time electrochemical detection of ATP and H₂O₂ release in freshly isolated kidneys. (Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Ryan RP, Cowley AW Jr, Staruschenko A) Am J Physiol Renal Physiol 2013 Jul 01;305(1):F134-41 PMID: 23594827 PMCID: PMC3725679 SCOPUS ID: 2-s2.0-84879596730 04/19/2013 35 Citations

Salt in health and disease--a delicate balance. (Kotchen TA, Cowley AW Jr, Frohlich ED) N Engl J Med 2013 Mar 28;368(13):1229-37 PMID: 23534562 SCOPUS ID: 2-s2.0-84875502772 03/29/2013 153 Citations

Dynamic genetic linkage of intermediate blood pressure phenotypes during postural adaptations in a founder population. (Arenas IA, Tremblay J, Deslauriers B, Sandoval J, Šeda O, Gaudet D, Merlo E, Kotchen T, Cowley AW Jr, Hamet P) Physiol Genomics 2013 Feb 15;45(4):138-50 PMID: 23269701 PMCID: PMC3774577 SCOPUS ID: 2-s2.0-84874062990 12/28/2012 7 Citations

Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat. (Yang C, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Skelton M, O'Connor P, Kurth T, Ryan RP, Moreno C, Tsaih SW, Patone G, Hummel O, Jacob HJ, Liang M, Cowley AW Jr) Hypertension 2013 Jan;61(1):208-15 PMID: 23184381 PMCID: PMC3760736 SCOPUS ID: 2-s2.0-84871619201 11/28/2012 18 Citations

PPAR-ϒ pathway to vascular dysfunction. (Lombard JH, Cowley AW Jr) Cell Metab 2012 Oct 03;16(4):410-1 PMID: 23040065 SCOPUS ID: 2-s2.0-84867067338 10/09/2012

Medullary thick ascending limb buffer vasoconstriction of renal outer-medullary vasa recta in salt-resistant but not salt-sensitive rats. (O'Connor PM, Cowley AW Jr) Hypertension 2012 Oct;60(4):965-72 PMID: 22926950 PMCID: PMC3785299 SCOPUS ID: 2-s2.0-84866562683 08/29/2012 19 Citations

Mitochondrial proteomic analysis reveals deficiencies in oxygen utilization in medullary thick ascending limb of Henle in the Dahl salt-sensitive rat. (Zheleznova NN, Yang C, Ryan RP, Halligan BD, Liang M, Greene AS, Cowley AW Jr) Physiol Genomics 2012 Sep 01;44(17):829-42 PMID: 22805345 PMCID: PMC3472460 SCOPUS ID: 2-s2.0-84865819868 07/19/2012 47 Citations

Non-replication study of a genome-wide association study for hypertension and blood pressure in African Americans. (Kidambi S, Ghosh S, Kotchen JM, Grim CE, Krishnaswami S, Kaldunski ML, Cowley AW Jr, Patel SB, Kotchen TA) BMC Med Genet 2012 Apr 11;13:27 PMID: 22494468 PMCID: PMC3349540 SCOPUS ID: 2-s2.0-84859506440 04/13/2012 33 Citations

Report of the National Heart, Lung, and Blood Institute Working Group on epigenetics and hypertension. (Cowley AW Jr, Nadeau JH, Baccarelli A, Berecek K, Fornage M, Gibbons GH, Harrison DG, Liang M, Nathanielsz PW, O'Connor DT, Ordovas J, Peng W, Soares MB, Szyf M, Tolunay HE, Wood KC, Zhao K, Galis ZS) Hypertension 2012 May;59(5):899-905 PMID: 22431584 PMCID: PMC3885905 SCOPUS ID: 2-s2.0-84860218599 03/21/2012 88 Citations

Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. (Feng D, Yang C, Geurts AM, Kurth T, Liang M, Lazar J, Mattson DL, O'Connor PM, Cowley AW Jr) Cell Metab 2012 Feb 08;15(2):201-8 PMID: 22326221 PMCID: PMC3280886 SCOPUS ID: 2-s2.0-84863012892 02/14/2012 129 Citations

Genetic mapping of habitual substance use, obesity-related traits, responses to mental and physical stress, and heart rate and blood pressure measurements reveals shared genes that are overrepresented in the neural synapse. (Nikpay M, Šeda O, Tremblay J, Petrovich M, Gaudet D, Kotchen TA, Cowley AW Jr, Hamet P) Hypertens Res 2012 Jun;35(6):585-91 PMID: 22297481 PMCID: PMC3368234 SCOPUS ID: 2-s2.0-84861883171 02/03/2012 39 Citations

Increase of sodium delivery stimulates the mitochondrial respiratory chain H2O2 production in rat renal medullary thick ascending limb. (Ohsaki Y, O'Connor P, Mori T, Ryan RP, Dickinson BC, Chang CJ, Lu Y, Ito S, Cowley AW Jr) Am J Physiol Renal Physiol 2012 Jan 01;302(1):F95-F102 PMID: 21975873 PMCID: PMC3251339 SCOPUS ID: 2-s2.0-83455242850 10/07/2011 49 Citations

NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli. (Ilatovskaya DV, Levchenko V, Ryan RP, Cowley AW Jr, Staruschenko A) Biochem Biophys Res Commun 2011 May 06;408(2):242-7 PMID: 21473850 PMCID: PMC3093766 SCOPUS ID: 2-s2.0-79955662243 04/09/2011 21 Citations

Renal injury in angiotensin II+L-NAME-induced hypertensive rats is independent of elevated blood pressure. (Polichnowski AJ, Lu L, Cowley AW Jr) Am J Physiol Renal Physiol 2011 Apr;300(4):F1008-16 PMID: 21270093 PMCID: PMC3074995 SCOPUS ID: 2-s2.0-79954469664 01/29/2011 26 Citations

Narrowing a region on rat chromosome 13 that protects against hypertension in Dahl SS-13BN congenic strains. (Moreno C, Williams JM, Lu L, Liang M, Lazar J, Jacob HJ, Cowley AW Jr, Roman RJ) Am J Physiol Heart Circ Physiol 2011 Apr;300(4):H1530-5 PMID: 21257920 PMCID: PMC3075031 SCOPUS ID: 2-s2.0-79955067680 01/25/2011 28 Citations

Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. (Cowley AW Jr) J Appl Physiol (1985) 2010 Dec;109(6):2009-10 PMID: 21188824 SCOPUS ID: 2-s2.0-78651293178 12/29/2010

Temporomandibular disorders and associated clinical comorbidities. (Hoffmann RG, Kotchen JM, Kotchen TA, Cowley T, Dasgupta M, Cowley AW Jr) Clin J Pain 2011;27(3):268-74 PMID: 21178593 12/24/2010

Analyzing complex traits with congenic strains. (Shao H, Sinasac DS, Burrage LC, Hodges CA, Supelak PJ, Palmert MR, Moreno C, Cowley AW Jr, Jacob HJ, Nadeau JH) Mamm Genome 2010 Jun;21(5-6):276-86 PMID: 20524000 PMCID: PMC3805105 SCOPUS ID: 2-s2.0-77955656946 06/05/2010 41 Citations

Modulation of pressure-natriuresis by renal medullary reactive oxygen species and nitric oxide. (O'Connor PM, Cowley AW Jr) Curr Hypertens Rep 2010 Apr;12(2):86-92 PMID: 20424940 PMCID: PMC3722865 SCOPUS ID: 2-s2.0-77953538736 04/29/2010 59 Citations

Role of renal perfusion pressure versus angiotensin II on renal oxidative stress in angiotensin II-induced hypertensive rats. (Polichnowski AJ, Jin C, Yang C, Cowley AW Jr) Hypertension 2010 Jun;55(6):1425-30 PMID: 20404214 PMCID: PMC2884003 SCOPUS ID: 2-s2.0-77952957963 04/21/2010 30 Citations

Identifying physiological origins of baroreflex dysfunction in salt-sensitive hypertension in the Dahl SS rat. (Bugenhagen SM, Cowley AW Jr, Beard DA) Physiol Genomics 2010 Jun;42(1):23-41 PMID: 20354102 PMCID: PMC2888563 SCOPUS ID: 2-s2.0-77953223380 04/01/2010 49 Citations

Renal medullary microRNAs in Dahl salt-sensitive rats: miR-29b regulates several collagens and related genes. (Liu Y, Taylor NE, Lu L, Usa K, Cowley AW Jr, Ferreri NR, Yeo NC, Liang M) Hypertension 2010 Apr;55(4):974-82 PMID: 20194304 PMCID: PMC2862728 SCOPUS ID: 2-s2.0-77950500403 03/03/2010 229 Citations

Dynamic convergence and divergence of renal genomic and biological pathways in protection from Dahl salt-sensitive hypertension. (Lu L, Li P, Yang C, Kurth T, Misale M, Skelton M, Moreno C, Roman RJ, Greene AS, Jacob HJ, Lazar J, Liang M, Cowley AW Jr) Physiol Genomics 2010 Mar 03;41(1):63-70 PMID: 20009007 PMCID: PMC2841498 SCOPUS ID: 2-s2.0-77949685598 12/17/2009 28 Citations

Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. (Beetz N, Harrison MD, Brede M, Zong X, Urbanski MJ, Sietmann A, Kaufling J, Lorkowski S, Barrot M, Seeliger MW, Vieira-Coelho MA, Hamet P, Gaudet D, Seda O, Tremblay J, Kotchen TA, Kaldunski M, Nüsing R, Szabo B, Jacob HJ, Cowley AW Jr, Biel M, Stoll M, Lohse MJ, Broeckel U, Hein L) J Clin Invest 2009 Dec;119(12):3597-3612 PMID: 19959875 PMCID: PMC2786789 SCOPUS ID: 2-s2.0-72849116579 12/05/2009 43 Citations

Pressure-induced renal injury in angiotensin II versus norepinephrine-induced hypertensive rats. (Polichnowski AJ, Cowley AW Jr) Hypertension 2009 Dec;54(6):1269-77 PMID: 19858406 PMCID: PMC2812436 SCOPUS ID: 2-s2.0-73349112594 10/28/2009 42 Citations

A novel amiloride-sensitive h+ transport pathway mediates enhanced superoxide production in thick ascending limb of salt-sensitive rats, not na+/h+ exchange. (O'Connor PM, Lu L, Liang M, Cowley AW Jr) Hypertension 2009 Aug;54(2):248-54 PMID: 19564541 PMCID: PMC2771701 SCOPUS ID: 2-s2.0-68549085337 07/01/2009 17 Citations

Novel role of fumarate metabolism in dahl-salt sensitive hypertension. (Tian Z, Liu Y, Usa K, Mladinov D, Fang Y, Ding X, Greene AS, Cowley AW Jr, Liang M) Hypertension 2009 Aug;54(2):255-60 PMID: 19546378 PMCID: PMC2721687 SCOPUS ID: 2-s2.0-68549122792 06/24/2009 67 Citations

Effects of renal perfusion pressure on renal medullary hydrogen peroxide and nitric oxide production. (Jin C, Hu C, Polichnowski A, Mori T, Skelton M, Ito S, Cowley AW Jr) Hypertension 2009 Jun;53(6):1048-53 PMID: 19433780 PMCID: PMC2777807 SCOPUS ID: 2-s2.0-67049158577 05/13/2009 46 Citations

MicroRNA: a new frontier in kidney and blood pressure research. (Liang M, Liu Y, Mladinov D, Cowley AW Jr, Trivedi H, Fang Y, Xu X, Ding X, Tian Z) Am J Physiol Renal Physiol 2009 Sep;297(3):F553-8 PMID: 19339633 PMCID: PMC2739705 SCOPUS ID: 2-s2.0-67650259138 04/03/2009 92 Citations

Research recommendations from the fifth scientific meeting of the TMJ association: can studies of comorbidities with tmjds reveal common mechanisms of disease? (Cowley AW Jr) J Oral Rehabil 2009 Apr;36(4):237-9 PMID: 19278375 SCOPUS ID: 2-s2.0-61849099858 03/13/2009

Renal medullary oxidative stress, pressure-natriuresis, and hypertension. (Cowley AW Jr) Hypertension 2008 Nov;52(5):777-86 PMID: 18852392 PMCID: PMC2659638 SCOPUS ID: 2-s2.0-55949136578 10/15/2008 135 Citations

Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. (Mattson DL, Dwinell MR, Greene AS, Kwitek AE, Roman RJ, Jacob HJ, Cowley AW Jr) Am J Physiol Renal Physiol 2008 Sep;295(3):F837-42 PMID: 18653478 PMCID: PMC2536867 SCOPUS ID: 2-s2.0-54449084434 07/26/2008 97 Citations

Enhanced amiloride-sensitive superoxide production in renal medullary thick ascending limb of Dahl salt-sensitive rats. (O'Connor PM, Lu L, Schreck C, Cowley AW Jr) Am J Physiol Renal Physiol 2008 Sep;295(3):F726-33 PMID: 18579705 PMCID: PMC2536875 SCOPUS ID: 2-s2.0-54449098442 06/27/2008 19 Citations

Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic rats. (Liang M, Lee NH, Wang H, Greene AS, Kwitek AE, Kaldunski ML, Luu TV, Frank BC, Bugenhagen S, Jacob HJ, Cowley AW Jr) Physiol Genomics 2008 Jun 12;34(1):54-64 PMID: 18430809 SCOPUS ID: 2-s2.0-47249097572 04/24/2008 43 Citations

High perfusion pressure accelerates renal injury in salt-sensitive hypertension. (Mori T, Polichnowski A, Glocka P, Kaldunski M, Ohsaki Y, Liang M, Cowley AW Jr) J Am Soc Nephrol 2008 Aug;19(8):1472-82 PMID: 18417720 PMCID: PMC2488259 SCOPUS ID: 2-s2.0-49649100283 04/18/2008 94 Citations

Renal regional proteomes in young Dahl salt-sensitive rats. (Tian Z, Greene AS, Usa K, Matus IR, Bauwens J, Pietrusz JL, Cowley AW Jr, Liang M) Hypertension 2008 Apr;51(4):899-904 PMID: 18316652 SCOPUS ID: 2-s2.0-42049087447 03/05/2008 55 Citations

Systematic, genome-wide, sex-specific linkage of cardiovascular traits in French Canadians. (Seda O, Tremblay J, Gaudet D, Brunelle PL, Gurau A, Merlo E, Pilote L, Orlov SN, Boulva F, Petrovich M, Kotchen TA, Cowley AW Jr, Hamet P) Hypertension 2008 Apr;51(4):1156-62 PMID: 18259002 SCOPUS ID: 2-s2.0-40849142430 02/09/2008 41 Citations

Harnessing "omic" tools and computational hypothesis-driven approaches to understand biocomplexity: the future of Physiological Genomics. (Cowley AW Jr) Physiol Genomics 2008 Mar 14;33(1):1-2 PMID: 18198282 SCOPUS ID: 2-s2.0-41349089929 01/17/2008 3 Citations

Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats. (Mattson DL, Dwinell MR, Greene AS, Kwitek AE, Roman RJ, Cowley AW Jr, Jacob HJ) Am J Physiol Renal Physiol 2007 Dec;293(6):F1905-14 PMID: 17898042 SCOPUS ID: 2-s2.0-36549060031 09/28/2007 42 Citations

Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat. (Moreno C, Kaldunski ML, Wang T, Roman RJ, Greene AS, Lazar J, Jacob HJ, Cowley AW Jr) Physiol Genomics 2007 Oct 22;31(2):228-35 PMID: 17566075 SCOPUS ID: 2-s2.0-35548972551 06/15/2007 63 Citations

Vasopressin-induced nitric oxide production in rat inner medullary collecting duct is dependent on V2 receptor activation of the phosphoinositide pathway. (O'Connor PM, Cowley AW Jr) Am J Physiol Renal Physiol 2007 Aug;293(2):F526-32 PMID: 17507604 SCOPUS ID: 2-s2.0-34548409692 05/18/2007 24 Citations

Enhanced superoxide production in renal outer medulla of Dahl salt-sensitive rats reduces nitric oxide tubular-vascular cross-talk. (Mori T, O'Connor PM, Abe M, Cowley AW Jr) Hypertension 2007 Jun;49(6):1336-41 PMID: 17470722 SCOPUS ID: 2-s2.0-34249296718 05/02/2007 75 Citations

Genomics and proteomics of lung disease: conference summary. (Raj JU, Aliferis C, Caprioli RM, Cowley AW Jr, Davies PF, Duncan MW, Erle DJ, Erzurum SC, Finn PW, Ischiropoulos H, Kaminski N, Kleeberger SR, Leikauf GD, Loyd JE, Martin TR, Matalon S, Moore JH, Quackenbush J, Sabo-Attwood T, Shapiro SD, Schnitzer JE, Schwartz DA, Schwiebert LM, Sheppard D, Ware LB, Weiss ST, Whitsett JA, Wurfel MM, Matthay MA) Am J Physiol Lung Cell Mol Physiol 2007 Jul;293(1):L45-51 PMID: 17468134 PMCID: PMC4212816 SCOPUS ID: 2-s2.0-34447498867 05/01/2007 13 Citations

Efficient transgenic rat production by a lentiviral vector. (Michalkiewicz M, Michalkiewicz T, Geurts AM, Roman RJ, Slocum GR, Singer O, Weihrauch D, Greene AS, Kaldunski M, Verma IM, Jacob HJ, Cowley AW Jr) Am J Physiol Heart Circ Physiol 2007 Jul;293(1):H881-94 PMID: 17322424 SCOPUS ID: 2-s2.0-34547112080 02/27/2007 37 Citations

Relating cardiac performance with oxygen consumption: historical observations continue to spawn scientific discovery. (Gutterman DD, Cowley AW Jr) Am J Physiol Heart Circ Physiol 2006 Dec;291(6):H2555-6 PMID: 17090783 SCOPUS ID: 2-s2.0-33845395270 11/09/2006 22 Citations

NO synthase uncoupling in the kidney of Dahl S rats: role of dihydrobiopterin. (Taylor NE, Maier KG, Roman RJ, Cowley AW Jr) Hypertension 2006 Dec;48(6):1066-71 PMID: 17060509 SCOPUS ID: 2-s2.0-33751104204 10/25/2006 48 Citations

The genetic dissection of essential hypertension. (Cowley AW Jr) Nat Rev Genet 2006 Nov;7(11):829-40 PMID: 17033627 SCOPUS ID: 2-s2.0-33750202275 10/13/2006 244 Citations

Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. (Kunert MP, Drenjancevic-Peric I, Dwinell MR, Lombard JH, Cowley AW Jr, Greene AS, Kwitek AE, Jacob HJ) Physiol Genomics 2006 Aug 16;26(3):218-25 PMID: 16772359 SCOPUS ID: 2-s2.0-33747330104 06/15/2006 25 Citations

Effect of sodium delivery on superoxide and nitric oxide in the medullary thick ascending limb. (Abe M, O'Connor P, Kaldunski M, Liang M, Roman RJ, Cowley AW Jr) Am J Physiol Renal Physiol 2006 Aug;291(2):F350-7 PMID: 16597609 SCOPUS ID: 2-s2.0-33746583565 04/07/2006 64 Citations

NADPH oxidase in the renal medulla causes oxidative stress and contributes to salt-sensitive hypertension in Dahl S rats. (Taylor NE, Glocka P, Liang M, Cowley AW Jr) Hypertension 2006 Apr;47(4):692-8 PMID: 16505210 SCOPUS ID: 2-s2.0-33645832749 03/01/2006 174 Citations

Physiology and genomics: toward systems biology. (Cowley AW Jr, Liang M) Sheng Li Xue Bao 2006 Feb 25;58(1):1-4 PMID: 16489396 SCOPUS ID: 2-s2.0-84870580058 02/21/2006 1 Citation

BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. (Kwitek AE, Jacob HJ, Baker JE, Dwinell MR, Forster HV, Greene AS, Kunert MP, Lombard JH, Mattson DL, Pritchard KA Jr, Roman RJ, Tonellato PJ, Cowley AW Jr) Physiol Genomics 2006 Apr 13;25(2):303-13 PMID: 16478827 SCOPUS ID: 2-s2.0-33645761913 02/16/2006 31 Citations

Molecular mechanisms and therapeutic strategies of chronic renal injury: physiological role of angiotensin II-induced oxidative stress in renal medulla. (Mori T, Cowley AW Jr, Ito S) J Pharmacol Sci 2006 Jan;100(1):2-8 PMID: 16404134 SCOPUS ID: 2-s2.0-31544451830 01/13/2006 46 Citations

Effect of renal medullary H2O2 on salt-induced hypertension and renal injury. (Taylor NE, Cowley AW Jr) Am J Physiol Regul Integr Comp Physiol 2005 Dec;289(6):R1573-9 PMID: 16109803 SCOPUS ID: 2-s2.0-27844485560 08/20/2005 87 Citations

Cytochrome P-450-dependent metabolism of arachidonic acid in the kidney of rats with diabetes insipidus. (Sarkis A, Ito O, Mori T, Kohzuki M, Ito S, Verbalis J, Cowley AW Jr, Roman RJ) Am J Physiol Renal Physiol 2005 Dec;289(6):F1333-40 PMID: 16014574 SCOPUS ID: 2-s2.0-27944466804 07/15/2005 6 Citations

Transcriptome analysis and kidney research: toward systems biology. (Liang M, Cowley AW Jr, Hessner MJ, Lazar J, Basile DP, Pietrusz JL) Kidney Int 2005 Jun;67(6):2114-22 PMID: 15882254 SCOPUS ID: 2-s2.0-23044515192 05/11/2005 23 Citations

Quantitative founder-effect analysis of French Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension. (Hamet P, Merlo E, Seda O, Broeckel U, Tremblay J, Kaldunski M, Gaudet D, Bouchard G, Deslauriers B, Gagnon F, Antoniol G, Pausová Z, Labuda M, Jomphe M, Gossard F, Tremblay G, Kirova R, Tonellato P, Orlov SN, Pintos J, Platko J, Hudson TJ, Rioux JD, Kotchen TA, Cowley AW Jr) Am J Hum Genet 2005 May;76(5):815-32 PMID: 15800845 PMCID: PMC1199371 SCOPUS ID: 2-s2.0-20244390026 04/01/2005 72 Citations

Hyperaldosteronism and hypertension: ethnic differences. (Grim CE, Cowley AW Jr, Hamet P, Gaudet D, Kaldunski ML, Kotchen JM, Krishnaswami S, Pausova Z, Roman R, Tremblay J, Kotchen TA) Hypertension 2005 Apr;45(4):766-72 PMID: 15699471 SCOPUS ID: 2-s2.0-20144369497 02/09/2005 86 Citations

Genetic determinants on rat chromosome 6 modulate variation in the hypercapnic ventilatory response using consomic strains. (Dwinell MR, Forster HV, Petersen J, Rider A, Kunert MP, Cowley AW Jr, Jacob HJ) J Appl Physiol (1985) 2005 May;98(5):1630-8 PMID: 15661838 SCOPUS ID: 2-s2.0-17644403141 01/22/2005 15 Citations

Substitution of chromosome 1 ameliorates L-NAME hypertension and renal disease in the fawn-hooded hypertensive rat. (Mattson DL, Kunert MP, Roman RJ, Jacob HJ, Cowley AW Jr) Am J Physiol Renal Physiol 2005 May;288(5):F1015-22 PMID: 15644486 SCOPUS ID: 2-s2.0-17644386821 01/13/2005 30 Citations

Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure. (Basile DP, Fredrich K, Alausa M, Vio CP, Liang M, Rieder MR, Greene AS, Cowley AW Jr) Am J Physiol Renal Physiol 2005 May;288(5):F953-63 PMID: 15632414 SCOPUS ID: 2-s2.0-17644427987 01/06/2005 90 Citations

Consomic rat model systems for physiological genomics. (Cowley AW Jr, Liang M, Roman RJ, Greene AS, Jacob HJ) Acta Physiol Scand 2004 Aug;181(4):585-92 PMID: 15283774 SCOPUS ID: 2-s2.0-4043089215 07/31/2004 110 Citations

Role of pressure in angiotensin II-induced renal injury: chronic servo-control of renal perfusion pressure in rats. (Mori T, Cowley AW Jr) Hypertension 2004 Apr;43(4):752-9 PMID: 14981064 SCOPUS ID: 2-s2.0-1642460697 02/26/2004 113 Citations

The elusive field of systems biology. (Cowley AW Jr) Physiol Genomics 2004 Feb 13;16(3):285-6 PMID: 14966250 SCOPUS ID: 2-s2.0-1842430596 02/18/2004 22 Citations

Renal oxidative stress in medullary thick ascending limbs produced by elevated NaCl and glucose. (Mori T, Cowley AW Jr) Hypertension 2004 Feb;43(2):341-6 PMID: 14718354 SCOPUS ID: 2-s2.0-0842268296 01/14/2004 72 Citations

Application of chromosomal substitution techniques in gene-function discovery. (Cowley AW Jr, Roman RJ, Jacob HJ) J Physiol 2004 Jan 01;554(Pt 1):46-55 PMID: 14678490 PMCID: PMC1664739 SCOPUS ID: 2-s2.0-0346294232 12/18/2003 97 Citations

Reactive oxygen species and molecular regulation of renal oxygenation. (Zou AP, Cowley AW Jr) Acta Physiol Scand 2003 Nov;179(3):233-41 PMID: 14616239 SCOPUS ID: 2-s2.0-0345304232 11/18/2003 73 Citations

Influence of diet and genetics on hypertension and renal disease in Dahl salt-sensitive rats. (Mattson DL, Kunert MP, Kaldunski ML, Greene AS, Roman RJ, Jacob HJ, Cowley AW Jr) Physiol Genomics 2004 Jan 15;16(2):194-203 PMID: 14600213 SCOPUS ID: 2-s2.0-1442282936 11/06/2003 74 Citations

Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats. (Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr) Physiol Genomics 2003 Nov 11;15(3):243-57 PMID: 14532335 SCOPUS ID: 2-s2.0-20244376857 10/09/2003 87 Citations

Angiotensin II-NAD(P)H oxidase-stimulated superoxide modifies tubulovascular nitric oxide cross-talk in renal outer medulla. (Mori T, Cowley AW Jr) Hypertension 2003 Oct;42(4):588-93 PMID: 12975384 SCOPUS ID: 2-s2.0-0141893554 09/17/2003 90 Citations

Physiological Genomics: the next three years. (Cowley AW Jr) Physiol Genomics 2003 Aug 15;14(3):169-70 PMID: 12923299 SCOPUS ID: 2-s2.0-0141798517 08/19/2003 3 Citations

In memoriam. Arthur C. Guyton (1919-2003). (Hall JE, Cowley AW Jr, Bishop VS, Granger DN, Navar LG, Taylor AE) Physiologist 2003 Jun;46(3):126-8 PMID: 12870325 SCOPUS ID: 2-s2.0-0042969216 07/23/2003 7 Citations

Consomic rats for the identification of genes and pathways underlying cardiovascular disease. (Roman RJ, Cowley AW Jr, Greene A, Kwitek AE, Tonellato PJ, Jacob HJ) Cold Spring Harb Symp Quant Biol 2002;67:309-15 PMID: 12858554 SCOPUS ID: 2-s2.0-0038124351 07/16/2003 20 Citations

Quantitative assessment of the importance of dye switching and biological replication in cDNA microarray studies. (Liang M, Briggs AG, Rute E, Greene AS, Cowley AW Jr) Physiol Genomics 2003 Aug 15;14(3):199-207 PMID: 12799473 SCOPUS ID: 2-s2.0-0141798522 06/12/2003 36 Citations

Increased H(2)O(2) counteracts the vasodilator and natriuretic effects of superoxide dismutation by tempol in renal medulla. (Chen YF, Cowley AW Jr, Zou AP) Am J Physiol Regul Integr Comp Physiol 2003 Oct;285(4):R827-33 PMID: 12791586 SCOPUS ID: 2-s2.0-0141792792 06/07/2003 111 Citations

Increased renal medullary H2O2 leads to hypertension. (Makino A, Skelton MM, Zou AP, Cowley AW Jr) Hypertension 2003 Jul;42(1):25-30 PMID: 12782642 SCOPUS ID: 2-s2.0-0038480710 06/05/2003 126 Citations

Role of renal NO production in the regulation of medullary blood flow. (Cowley AW Jr, Mori T, Mattson D, Zou AP) Am J Physiol Regul Integr Comp Physiol 2003 Jun;284(6):R1355-69 PMID: 12736168 SCOPUS ID: 2-s2.0-0038811878 05/09/2003 194 Citations

Gene expression reveals vulnerability to oxidative stress and interstitial fibrosis of renal outer medulla to nonhypertensive elevations of ANG II. (Yuan B, Liang M, Yang Z, Rute E, Taylor N, Olivier M, Cowley AW Jr) Am J Physiol Regul Integr Comp Physiol 2003 May;284(5):R1219-30 PMID: 12676744 SCOPUS ID: 2-s2.0-0037404493 04/05/2003 27 Citations

Countercurrent exchange in the renal medulla. (Cowley AW Jr, Roman RR) Am J Physiol Regul Integr Comp Physiol 2003 May;284(5):R1151 PMID: 12676740 SCOPUS ID: 2-s2.0-0037405141 04/05/2003 11 Citations

Genomics and homeostasis. (Cowley AW Jr) Am J Physiol Regul Integr Comp Physiol 2003 Mar;284(3):R611-27 PMID: 12571070 SCOPUS ID: 2-s2.0-0037342699 02/07/2003 47 Citations

Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression. (Liang M, Yuan B, Rute E, Greene AS, Olivier M, Cowley AW Jr) Physiol Genomics 2003 Feb 06;12(3):229-37 PMID: 12488510 SCOPUS ID: 2-s2.0-0141482413 12/19/2002 55 Citations

Identification of hypertension-related QTLs in African American sib pairs. (Kotchen TA, Broeckel U, Grim CE, Hamet P, Jacob H, Kaldunski ML, Kotchen JM, Schork NJ, Tonellato PJ, Cowley AW Jr) Hypertension 2002 Nov;40(5):634-9 PMID: 12411455 SCOPUS ID: 2-s2.0-0036840308 11/02/2002 22 Citations

Tubulovascular nitric oxide crosstalk: buffering of angiotensin II-induced medullary vasoconstriction. (Dickhout JG, Mori T, Cowley AW Jr) Circ Res 2002 Sep 20;91(6):487-93 PMID: 12242266 SCOPUS ID: 2-s2.0-0037144663 09/21/2002 99 Citations

Axial stretching of extremity artery induces reversible hyperpolarization of smooth muscle cell membrane in vivo. (Monos E, Raffai G, Contney SJ, Stekiel WJ, Cowley AW Jr) Acta Physiol Hung 2001;88(3-4):197-206 PMID: 12162578 SCOPUS ID: 2-s2.0-0035552354 08/07/2002 3 Citations

Renal medullary nitric oxide deficit of Dahl S rats enhances hypertensive actions of angiotensin II. (Szentiványi M Jr, Zou AP, Mattson DL, Soares P, Moreno C, Roman RJ, Cowley AW Jr) Am J Physiol Regul Integr Comp Physiol 2002 Jul;283(1):R266-72 PMID: 12069953 SCOPUS ID: 2-s2.0-0036340195 06/19/2002 72 Citations

Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II. (Alonso-Galicia M, Maier KG, Greene AS, Cowley AW Jr, Roman RJ) Am J Physiol Regul Integr Comp Physiol 2002 Jul;283(1):R60-8 PMID: 12069931 SCOPUS ID: 2-s2.0-0036333483 06/19/2002 137 Citations

Mapping baroreceptor function to genome: a mathematical modeling approach. (Kendziorski CM, Cowley AW Jr, Greene AS, Salgado HC, Jacob HJ, Tonellato PJ) Genetics 2002 Apr;160(4):1687-95 PMID: 11973321 PMCID: PMC1462065 SCOPUS ID: 2-s2.0-0036236799 04/26/2002 11 Citations

Increased renal medullary oxidative stress produces hypertension. (Makino A, Skelton MM, Zou AP, Roman RJ, Cowley AW Jr) Hypertension 2002 Feb;39(2 Pt 2):667-72 PMID: 11882628 SCOPUS ID: 2-s2.0-0036181930 03/08/2002 153 Citations

Vasopressin increases intracellular NO concentration via Ca(2+) signaling in inner medullary collecting duct. (Mori T, Dickhout JG, Cowley AW Jr) Hypertension 2002 Feb;39(2 Pt 2):465-9 PMID: 11882591 SCOPUS ID: 2-s2.0-0036175379 03/08/2002 31 Citations

Renal medullary genes in salt-sensitive hypertension: a chromosomal substitution and cDNA microarray study. (Liang M, Yuan B, Rute E, Greene AS, Zou AP, Soares P, MCQuestion GD, Slocum GR, Jacob HJ, Cowley AW Jr) Physiol Genomics 2002 Feb 28;8(2):139-49 PMID: 11875192 SCOPUS ID: 2-s2.0-0037186992 03/05/2002 47 Citations

A genomic-systems biology map for cardiovascular function. (Stoll M, Cowley AW Jr, Tonellato PJ, Greene AS, Kaldunski ML, Roman RJ, Dumas P, Schork NJ, Wang Z, Jacob HJ) Science 2001 Nov 23;294(5547):1723-6 PMID: 11721057 SCOPUS ID: 2-s2.0-0035940943 11/27/2001 153 Citations

Oxygen-dependent expression of hypoxia-inducible factor-1alpha in renal medullary cells of rats. (Zou AP, Yang ZZ, Li PL, Cowley AW JR) Physiol Genomics 2001 Aug 28;6(3):159-68 PMID: 11526200 SCOPUS ID: 2-s2.0-0347711871 08/30/2001 52 Citations

Production and actions of superoxide in the renal medulla. (Zou AP, Li N, Cowley AW Jr) Hypertension 2001 Feb;37(2 Pt 2):547-53 PMID: 11230333 SCOPUS ID: 2-s2.0-0035097458 03/07/2001 278 Citations

Evidence that reduced renal medullary nitric oxide synthase activity of dahl s rats enables small elevations of arginine vasopressin to produce sustained hypertension. (Yuan B, Cowley AW Jr) Hypertension 2001 Feb;37(2 Pt 2):524-8 PMID: 11230329 SCOPUS ID: 2-s2.0-0035090402 03/07/2001 36 Citations

Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. (Cowley AW Jr, Roman RJ, Kaldunski ML, Dumas P, Dickhout JG, Greene AS, Jacob HJ) Hypertension 2001 Feb;37(2 Pt 2):456-61 PMID: 11230318 SCOPUS ID: 2-s2.0-0035094728 03/07/2001 177 Citations

Measurement of regional blood flow in the kidney using laser-Doppler flowmetry. (Roman RJ, Mattson DL, Cowley AW Jr) Methods Mol Med 2001;51:407-26 PMID: 21331733 01/01/2001

Tubulointerstitial injury and loss of nitric oxide synthases parallel the development of hypertension in the Dahl-SS rat. (Johnson RJ, Gordon KL, Giachelli C, Kurth T, Skelton MM, Cowley AW Jr) J Hypertens 2000 Oct;18(10):1497-505 PMID: 11057439 SCOPUS ID: 2-s2.0-0033785784 11/01/2000 64 Citations

Genetically defined risk of salt sensitivity in an intercross of Brown Norway and Dahl S rats. (Cowley AW Jr, Stoll M, Greene AS, Kaldunski ML, Roman RJ, Tonellato PJ, Schork NJ, Dumas P, Jacob HJ) Physiol Genomics 2000 Apr 27;2(3):107-15 PMID: 11015589 SCOPUS ID: 2-s2.0-0034719983 10/04/2000 71 Citations

Role of nitric oxide in the control of renal function and salt sensitivity. (Zou AP, Cowley AW Jr) Curr Hypertens Rep 1999;1(2):178-86 PMID: 10981063 SCOPUS ID: 2-s2.0-0033108016 09/12/2000 70 Citations

alpha(2)-adrenergic receptor-mediated increase in NO production buffers renal medullary vasoconstriction. (Zou AP, Cowley AW Jr) Am J Physiol Regul Integr Comp Physiol 2000 Sep;279(3):R769-77 PMID: 10956233 SCOPUS ID: 2-s2.0-0033834677 08/24/2000 69 Citations

Control of the renal medullary circulation by vasopressin V1 and V2 receptors in the rat. (Cowley AW Jr) Exp Physiol 2000 Mar;85 Spec No:223S-231S PMID: 10795926 SCOPUS ID: 2-s2.0-0342859342 05/05/2000 50 Citations

New target regions for human hypertension via comparative genomics. (Stoll M, Kwitek-Black AE, Cowley AW Jr, Harris EL, Harrap SB, Krieger JE, Printz MP, Provoost AP, Sassard J, Jacob HJ) Genome Res 2000 Apr;10(4):473-82 PMID: 10779487 PMCID: PMC310887 SCOPUS ID: 2-s2.0-0034098728 04/26/2000 204 Citations

Nitric oxide in the renal medulla protects from vasopressin-induced hypertension. (Szentiványi M Jr, Park F, Maeda CY, Cowley AW Jr) Hypertension 2000 Mar;35(3):740-5 PMID: 10720588 SCOPUS ID: 2-s2.0-4243704027 03/18/2000 45 Citations

Increase in renal medullary nitric oxide synthase activity protects from norepinephrine-induced hypertension. (Szentiványi M Jr, Zou AP, Maeda CY, Mattson DL, Cowley AW Jr) Hypertension 2000 Jan;35(1 Pt 2):418-23 PMID: 10642335 SCOPUS ID: 2-s2.0-0342514748 01/21/2000 34 Citations

Expression and actions of heme oxygenase in the renal medulla of rats. (Zou AP, Billington H, Su N, Cowley AW Jr) Hypertension 2000 Jan;35(1 Pt 2):342-7 PMID: 10642322 SCOPUS ID: 2-s2.0-0033979878 01/21/2000 93 Citations

Chronic salt loading and the expression of adenosine receptor subtypes. (Nayeem MA, Olanrewaju HA, Mustafa SJ, Li PL, Cowley AW Jr) Hypertension 1999 Dec;34(6):e18-9 PMID: 10601139 SCOPUS ID: 2-s2.0-0033443172 12/22/1999 3 Citations

Distribution of angiotensin AT1 and AT2 receptor subtypes in the rat kidney. (Miyata N, Park F, Li XF, Cowley AW Jr) Am J Physiol 1999 Sep;277(3):F437-46 PMID: 10484527 SCOPUS ID: 2-s2.0-0033194720 09/14/1999 277 Citations

Quantification of nitric oxide synthase activity in microdissected segments of the rat kidney. (Wu F, Park F, Cowley AW Jr, Mattson DL) Am J Physiol 1999 Jun;276(6):F874-81 PMID: 10362776 SCOPUS ID: 2-s2.0-0033000931 06/11/1999 182 Citations

The emergence of physiological genomics. (Cowley AW Jr) J Vasc Res 1999;36(2):83-90 PMID: 10213902 SCOPUS ID: 2-s2.0-0344258199 04/24/1999 10 Citations

Role of renal medullary adenosine in the control of blood flow and sodium excretion. (Zou AP, Nithipatikom K, Li PL, Cowley AW Jr) Am J Physiol 1999 Mar;276(3):R790-8 PMID: 10070140 SCOPUS ID: 2-s2.0-0032950243 03/10/1999 94 Citations

Renal intramedullary infusion of L-arginine prevents reduction of medullary blood flow and hypertension in Dahl salt-sensitive rats. (Miyata N, Cowley AW Jr) Hypertension 1999 Jan;33(1 Pt 2):446-50 PMID: 9931145 SCOPUS ID: 2-s2.0-0032898382 02/04/1999 82 Citations

Local renal medullary L-NAME infusion enhances the effect of long-term angiotensin II treatment. (Szentiványi M Jr, Maeda CY, Cowley AW Jr) Hypertension 1999 Jan;33(1 Pt 2):440-5 PMID: 9931144 SCOPUS ID: 2-s2.0-17144439617 02/04/1999 40 Citations

Effect of chronic salt loading on adenosine metabolism and receptor expression in renal cortex and medulla in rats. (Zou AP, Wu F, Li PL, Cowley AW Jr) Hypertension 1999 Jan;33(1 Pt 2):511-6 PMID: 9931157 SCOPUS ID: 2-s2.0-0032899717 02/04/1999 92 Citations

Arginine vasopressin-mediated stimulation of nitric oxide within the rat renal medulla. (Park F, Zou AP, Cowley AW Jr) Hypertension 1998 Nov;32(5):896-901 PMID: 9822450 SCOPUS ID: 2-s2.0-0031738947 11/20/1998 54 Citations

Renal medullary interstitial infusion of L-arginine prevents hypertension in Dahl salt-sensitive rats. (Miyata N, Zou AP, Mattson DL, Cowley AW Jr) Am J Physiol 1998 Nov;275(5):R1667-73 PMID: 9791089 SCOPUS ID: 2-s2.0-0031765628 10/29/1998 61 Citations

Effects of long-term vasopressin receptor stimulation on medullary blood flow and arterial pressure. (Cowley AW Jr, Skelton MM, Kurth TM) Am J Physiol 1998 Nov;275(5):R1420-4 PMID: 9791056 SCOPUS ID: 2-s2.0-0031766361 10/29/1998 35 Citations

Pharmacological stimulation of arterial chemoreceptors in conscious rats produces differential responses in renal cortical and medullary blood flow. (Ledderhos C, Gross V, Cowley AW Jr) Clin Exp Pharmacol Physiol 1998;25(7-8):536-40 PMID: 9673424 SCOPUS ID: 2-s2.0-0031827496 07/23/1998 19 Citations

Effects of daily sodium intake and ANG II on cortical and medullary renal blood flow in conscious rats. (Gross V, Kurth TM, Skelton MM, Mattson DL, Cowley AW Jr) Am J Physiol 1998 May;274(5):R1317-23 PMID: 9644045 SCOPUS ID: 2-s2.0-0031831496 06/27/1998 45 Citations

Regional time-dependent changes in vasopressin V2 receptor expression in the rat kidney during water restriction. (Park F, Koike G, Cowley AW Jr) Am J Physiol 1998 May;274(5):F906-13 PMID: 9612328 SCOPUS ID: 2-s2.0-0031804017 06/05/1998 14 Citations

Regional time-dependent changes in vasopressin Vreceptor expression in the rat kidney during water restriction. (Park F, Koike G, Cowley AW Jr.) Am J Physiol Renal Physiol 1998 May 01;274(5):F906-F913 PMID: 29586430 05/01/1998

Protective effect of angiotensin II-induced increase in nitric oxide in the renal medullary circulation. (Zou AP, Wu F, Cowley AW Jr) Hypertension 1998 Jan;31(1 Pt 2):271-6 PMID: 9453315 SCOPUS ID: 2-s2.0-0031606438 02/07/1998 137 Citations

Inducible nitric oxide synthase and blood pressure. (Mattson DL, Maeda CY, Bachman TD, Cowley AW Jr) Hypertension 1998 Jan;31(1):15-20 PMID: 9449384 SCOPUS ID: 2-s2.0-0031939771 02/04/1998 81 Citations

Animal rights. (Cowley AW Jr, Schafer JA, Navar LG) Science 1997 Oct 24;278(5338):557; author reply 560 PMID: 9381149 01/10/1998

Evidence for the presence of smooth muscle alpha-actin within pericytes of the renal medulla. (Park F, Mattson DL, Roberts LA, Cowley AW Jr) Am J Physiol 1997 Nov;273(5):R1742-8 PMID: 9374818 SCOPUS ID: 2-s2.0-0030723250 12/31/1997 87 Citations

The Banbury Conference. Genomics to physiology and beyond: how do we get there? (Cowley AW Jr) Physiologist 1997 Oct;40(5):205-11 PMID: 9348747 SCOPUS ID: 2-s2.0-0031252733 12/31/1997 14 Citations

Evidence for the presence of smooth muscle α-actin within pericytes of the renal medulla. (Park F, Mattson DL, Roberts LA, Cowley AW Jr.) Am J Physiol Regul Integr Comp Physiol 1997 Nov 01;273(5):R1742-R1748 PMID: 29586565 11/01/1997

Role of nitric oxide in the control of the renal medullary circulation. (Mattson DL, Lu S, Cowley AW Jr) Clin Exp Pharmacol Physiol 1997 Aug;24(8):587-90 PMID: 9269532 SCOPUS ID: 2-s2.0-0030843105 08/01/1997 44 Citations

Localization of the vasopressin V1a and V2 receptors within the renal cortical and medullary circulation. (Park F, Mattson DL, Skelton MM, Cowley AW Jr) Am J Physiol 1997 Jul;273(1 Pt 2):R243-51 PMID: 9249556 SCOPUS ID: 2-s2.0-0031183039 07/11/1997 77 Citations

Role of the renal medulla in volume and arterial pressure regulation. (Cowley AW Jr) Am J Physiol 1997 Jul;273(1 Pt 2):R1-15 PMID: 9249526 SCOPUS ID: 2-s2.0-20644458768 07/11/1997 223 Citations

Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. (Herzig TC, Jobe SM, Aoki H, Molkentin JD, Cowley AW Jr, Izumo S, Markham BE) Proc Natl Acad Sci U S A 1997 Jul 08;94(14):7543-8 PMID: 9207128 PMCID: PMC23858 SCOPUS ID: 2-s2.0-0030612599 07/08/1997 183 Citations

Vasopressin modulation of medullary blood flow and pressure-natriuresis-diuresis in the decerebrated rat. (Franchini KG, Mattson DL, Cowley AW Jr) Am J Physiol 1997 May;272(5 Pt 2):R1472-9 PMID: 9176339 SCOPUS ID: 2-s2.0-0030909966 05/11/1997 29 Citations

Allen W. Cowley, Jr. 70th president of APS. Can APS capture the bright future of physiology? (Cowley AW Jr) Physiologist 1997 Apr;40(2):49, 58-64 PMID: 9128065 SCOPUS ID: 2-s2.0-0344725689 04/01/1997 2 Citations

Genetic and nongenetic determinants of salt sensitivity and blood pressure. (Cowley AW Jr) Am J Clin Nutr 1997 Feb;65(2 Suppl):587S-593S PMID: 9022553 SCOPUS ID: 2-s2.0-1842294593 02/01/1997 65 Citations

Nitric oxide in renal cortex and medulla. An in vivo microdialysis study. (Zou AP, Cowley AW Jr) Hypertension 1997 Jan;29(1 Pt 2):194-8 PMID: 9039101 SCOPUS ID: 2-s2.0-85026138276 01/01/1997 147 Citations

Sensitivity of the renal medullary circulation to plasma vasopressin. (Franchini KG, Cowley AW Jr) Am J Physiol 1996 Sep;271(3 Pt 2):R647-53 PMID: 8853387 SCOPUS ID: 2-s2.0-0029794208 09/11/1996 49 Citations

Renal cortical and medullary blood flow responses during water restriction: role of vasopressin. (Franchini KG, Cowley AW Jr) Am J Physiol 1996 Jun;270(6 Pt 2):R1257-64 PMID: 8764292 SCOPUS ID: 2-s2.0-0029801794 06/11/1996 66 Citations

The role of the kidney in hypertension. (Cowley AW Jr, Roman RJ) JAMA 1996 May 22-29;275(20):1581-9 PMID: 8622250 SCOPUS ID: 2-s2.0-0030004732 05/22/1996 248 Citations

Control of renal medullary blood flow by vasopressin V1 and V2 receptors. (Nakanishi K, Mattson DL, Gross V, Roman RJ, Cowley AW Jr) Am J Physiol 1995 Jul;269(1 Pt 2):R193-200 PMID: 7631893 SCOPUS ID: 2-s2.0-0028891157 07/11/1995 70 Citations

The renal medulla and hypertension. (Cowley AW Jr, Mattson DL, Lu S, Roman RJ) Hypertension 1995 Apr;25(4 Pt 2):663-73 PMID: 7721413 SCOPUS ID: 2-s2.0-0028945856 04/01/1995 216 Citations

In vivo diuretic actions of renal vasopressin V1 receptor stimulation in rats. (Ledderhos C, Mattson DL, Skelton MM, Cowley AW Jr) Am J Physiol 1995 Mar;268(3 Pt 2):R796-807 PMID: 7900923 SCOPUS ID: 2-s2.0-0028905478 03/11/1995 18 Citations

Role of renal medullary blood flow in the development of L-NAME hypertension in rats. (Nakanishi K, Mattson DL, Cowley AW Jr) Am J Physiol 1995 Feb;268(2 Pt 2):R317-23 PMID: 7864223 SCOPUS ID: 2-s2.0-0028945187 02/11/1995 101 Citations

A tribute to Eric Muirhead. Evolution of the Medullipin concept of blood pressure control. (Cowley AW Jr) Nephrol Dial Transplant 1995;10(7):1137-41 PMID: 7478113 SCOPUS ID: 2-s2.0-0029123384 01/01/1995 3 Citations

Franz Volhard Lecture. Evolution of the medullipin concept of blood pressure control: a tribute to Eric Muirhead. (Cowley AW Jr) J Hypertens Suppl 1994 Dec;12(10):S25-34 PMID: 7769488 SCOPUS ID: 2-s2.0-0028650686 12/01/1994 16 Citations

Prolonged stimulation of intrarenal V1 vasopressin receptors results in sustained hypertension. (Szczepanska-Sadowska E, Stepniakowski K, Skelton MM, Cowley AW Jr) Am J Physiol 1994 Nov;267(5 Pt 2):R1217-25 PMID: 7977848 SCOPUS ID: 2-s2.0-0028156720 11/11/1994 40 Citations

Hypertension induced by high salt intake in absence of volume retention in reduced renal mass rats. (Cowley AW Jr, Skelton MM, Papanek PE, Greene AS) Am J Physiol 1994 Nov;267(5 Pt 2):H1707-12 PMID: 7977802 SCOPUS ID: 2-s2.0-0028004262 11/11/1994 17 Citations

The effect of intracarotid vasopressin infusion on ACTH release in neurohypophysectomized, conscious dogs. (Raff H, Papanek PE, Liard JF, Cowley AW Jr) Am J Physiol 1994 Sep;267(3 Pt 2):R653-8 PMID: 8092308 SCOPUS ID: 2-s2.0-0028087687 09/11/1994 1 Citation

Abnormal pressure-natriuresis in transgenic renin gene rats. (Gross V, Roman RJ, Cowley AW Jr) J Hypertens 1994 Sep;12(9):1029-34 PMID: 7852745 SCOPUS ID: 2-s2.0-0028024534 09/01/1994 31 Citations

Chronic intravenous administration of V1 arginine vasopressin agonist results in sustained hypertension. (Cowley AW Jr, Szczepanska-Sadowska E, Stepniakowski K, Mattson D) Am J Physiol 1994 Aug;267(2 Pt 2):H751-6 PMID: 8067431 SCOPUS ID: 2-s2.0-0028037990 08/11/1994 42 Citations

Effect of chronic renal medullary nitric oxide inhibition on blood pressure. (Mattson DL, Lu S, Nakanishi K, Papanek PE, Cowley AW Jr) Am J Physiol 1994 May;266(5 Pt 2):H1918-26 PMID: 8203591 SCOPUS ID: 2-s2.0-0028121625 05/11/1994 194 Citations

Renal medullary captopril delivery lowers blood pressure in spontaneously hypertensive rats. (Lu S, Mattson DL, Cowley AW Jr) Hypertension 1994 Mar;23(3):337-45 PMID: 8125560 SCOPUS ID: 2-s2.0-0028294355 03/01/1994 81 Citations

Physiopathogenesis of acute aortic coarctation hypertension in conscious rats. (Salgado HC, Skelton MM, Salgado MC, Cowley AW Jr) Hypertension 1994 Jan;23(1 Suppl):I78-81 PMID: 8282379 SCOPUS ID: 2-s2.0-0028105812 01/01/1994 29 Citations

Imaging system for three-dimensional mapping of cerebrocortical capillary networks in vivo. (Hudetz AG, Greene AS, Fehér G, Knuese DE, Cowley AW Jr) Microvasc Res 1993 Nov;46(3):293-309 PMID: 8121315 SCOPUS ID: 2-s2.0-0027374735 11/01/1993 52 Citations

Chronic pressure-natriuresis relationship in dogs with inherited essential hypertension. (Papanek PE, Bovee KC, Skelton MM, Cowley AW Jr) Am J Hypertens 1993 Nov;6(11 Pt 1):960-7 PMID: 8305171 SCOPUS ID: 2-s2.0-0027527858 11/01/1993 7 Citations

Hyperpolarization of in situ rat saphenous vein in response to axial stretch. (Monos E, Contney SJ, Dörnyei G, Cowley AW Jr, Stekiel WJ) Am J Physiol 1993 Sep;265(3 Pt 2):H857-61 PMID: 8214119 SCOPUS ID: 2-s2.0-0027372865 09/11/1993 11 Citations

Assessment of changes in intrarenal blood flow in conscious rats using laser-Doppler flowmetry. (Lu S, Mattson DL, Roman RJ, Becker CG, Cowley AW Jr) Am J Physiol 1993 Jun;264(6 Pt 2):F956-62 PMID: 8322898 SCOPUS ID: 2-s2.0-0027174438 06/11/1993 45 Citations

Kinin actions on renal papillary blood flow and sodium excretion. (Mattson DL, Cowley AW Jr) Hypertension 1993 Jun;21(6 Pt 2):961-5 PMID: 8505107 SCOPUS ID: 2-s2.0-0027263226 06/01/1993 89 Citations

Relationship between renal perfusion pressure and blood flow in different regions of the kidney. (Mattson DL, Lu S, Roman RJ, Cowley AW Jr) Am J Physiol 1993 Mar;264(3 Pt 2):R578-83 PMID: 8457011 SCOPUS ID: 2-s2.0-0027483167 03/11/1993 139 Citations

ANP-mediated volume depletion attenuates renal responses in humans. (Ebert TJ, Groban L, Muzi M, Hanson M, Cowley AW Jr) Am J Physiol 1992 Dec;263(6 Pt 2):R1303-8 PMID: 1481943 SCOPUS ID: 2-s2.0-0027092802 12/11/1992 5 Citations

Whole body autoregulation in reduced renal mass hypertension. (Hinojosa-Laborde C, Frohlich BH, Cowley AW Jr) Hypertension 1992 Nov;20(5):659-65 PMID: 1358822 SCOPUS ID: 2-s2.0-0026744587 11/11/1992 15 Citations

Renal medullary interstitial infusion of diltiazem alters sodium and water excretion in rats. (Lu S, Roman RJ, Mattson DL, Cowley AW Jr) Am J Physiol 1992 Nov;263(5 Pt 2):R1064-70 PMID: 1443224 SCOPUS ID: 2-s2.0-0026488609 11/11/1992 66 Citations

Salt intake and angiotensin II alter microvessel density in the cremaster muscle of normal rats. (Hernandez I, Cowley AW Jr, Lombard JH, Greene AS) Am J Physiol 1992 Sep;263(3 Pt 2):H664-7 PMID: 1415589 SCOPUS ID: 2-s2.0-0026655481 09/11/1992 78 Citations

Saline diuresis and natriuresis in unanesthetized dogs: a missing atrial factor? (Cowley AW Jr, Brice AG, Skelton MM) Am J Physiol 1992 Sep;263(3 Pt 2):H792-7 PMID: 1415604 SCOPUS ID: 2-s2.0-0026781052 09/11/1992 4 Citations

Effect of hypotension and hyperosmolality on vasopressin and ACTH responses to hypoglycemia in conscious dogs. (Raff H, Papanek PE, Cowley AW Jr) Am J Physiol 1992 Aug;263(2 Pt 2):R382-8 PMID: 1324617 SCOPUS ID: 2-s2.0-0026731725 08/11/1992 7 Citations

Role of nitric oxide in renal papillary blood flow and sodium excretion. (Mattson DL, Roman RJ, Cowley AW Jr) Hypertension 1992 Jun;19(6 Pt 2):766-9 PMID: 1592478 SCOPUS ID: 2-s2.0-0026602775 06/11/1992 220 Citations

Working group on noncoronary cardiovascular disease and exercise in women. (Cowley AW Jr, Dzau V, Buttrick P, Cooke J, Devereux RB, Grines CL, Haidet GC, Thames MD) Med Sci Sports Exerc 1992 Jun;24(6 Suppl):S277-87 PMID: 1352614 SCOPUS ID: 2-s2.0-0026694083 06/11/1992 4 Citations

Effect of microvascular rarefaction on tissue oxygen delivery in hypertension. (Greene AS, Tonellato PJ, Zhang Z, Lombard JH, Cowley AW Jr) Am J Physiol 1992 May;262(5 Pt 2):H1486-93 PMID: 1590452 SCOPUS ID: 2-s2.0-0026690669 05/11/1992 48 Citations

Fluid-regulating hormones during exercise when central blood volume is increased by water immersion. (Sheldahl LM, Tristani FE, Connelly TP, Levandoski SG, Skelton MM, Cowley AW Jr) Am J Physiol 1992 May;262(5 Pt 2):R779-85 PMID: 1534205 SCOPUS ID: 2-s2.0-0026736336 05/11/1992 18 Citations

Baroreflex modulation of sympathetic outflow during physiological increases of vasopressin in humans. (Ebert TJ, Cowley AW Jr) Am J Physiol 1992 May;262(5 Pt 2):H1372-8 PMID: 1590441 SCOPUS ID: 2-s2.0-0026689124 05/11/1992 94 Citations

A Ca(2+)-dependent K+ current is enhanced in arterial membranes of hypertensive rats. (Rusch NJ, De Lucena RG, Wooldridge TA, England SK, Cowley AW Jr) Hypertension 1992 Apr;19(4):301-7 PMID: 1555863 SCOPUS ID: 2-s2.0-0026717465 04/11/1992 92 Citations

Long-term control of arterial blood pressure. (Cowley AW Jr) Physiol Rev 1992 Jan;72(1):231-300 PMID: 1731371 SCOPUS ID: 2-s2.0-0026500829 01/11/1992 527 Citations

Performance on multiple choice/short answer tests is not a sufficient criterion for evaluating the educational value of live animal laboratories in the teaching of physiology. (Dawson CA, Cowley AW Jr, Spurr GB, Osborn JL, Raff H, Forster HV, Harder DR, Liard JF, Lombard JH, Stekiel WJ) Am J Physiol 1991 Dec;261(6 Pt 3):S34-5 PMID: 1755480 SCOPUS ID: 2-s2.0-0026284575 12/11/1991 4 Citations

Dominance of colloid osmotic pressure in renal excretion after isotonic volume expansion. (Cowley AW Jr, Skelton MM) Am J Physiol 1991 Oct;261(4 Pt 2):H1214-25 PMID: 1928404 SCOPUS ID: 2-s2.0-0025942192 10/11/1991 35 Citations

Structural alterations of microvascular smooth muscle cells in reduced renal mass hypertension. (Hansen-Smith F, Greene AS, Cowley AW Jr, Lougee L, Lombard JH) Hypertension 1991 Jun;17(6 Pt 2):902-8 PMID: 2045171 SCOPUS ID: 2-s2.0-0025955408 06/01/1991 14 Citations

Contribution of regional vascular responses to whole body autoregulation in conscious areflexic rats. (Hinojosa-Laborde C, Frohlich BH, Cowley AW Jr) Hypertension 1991 Jun;17(6 Pt 2):1078-84 PMID: 2045152 SCOPUS ID: 2-s2.0-0026050538 06/01/1991 12 Citations

Relative roles of cardiac and arterial baroreceptors in vasopressin regulation during hemorrhage in conscious dogs. (Shen YT, Cowley AW Jr, Vatner SF) Circ Res 1991 May;68(5):1422-36 PMID: 2019000 SCOPUS ID: 2-s2.0-0025818817 05/01/1991 37 Citations

Salt and hypertension--future directions. (Cowley AW Jr) Hypertension 1991 Jan;17(1 Suppl):I205-10 PMID: 1987005 SCOPUS ID: 2-s2.0-0026101235 01/11/1991 8 Citations

ACTH and vasopressin responses to insulin-induced hypoglycemia in intact and neurohypophysectomized conscious dogs. (Raff H, Papanek PE, Cowley AW Jr) Neuroendocrinology 1991 Jan;53(1):85-90 PMID: 1646414 SCOPUS ID: 2-s2.0-0026089346 01/11/1991 16 Citations

Pathways linking renal excretion and arterial pressure with vascular structure and function. (Cowley AW Jr, Roman RJ, Krieger JE) Clin Exp Pharmacol Physiol 1991 Jan;18(1):21-7 PMID: 2032385 SCOPUS ID: 2-s2.0-0026071018 01/01/1991 8 Citations

Hemodynamics, fluid volume, and hormonal responses to chronic high-salt intake in dogs. (Krieger JE, Liard JF, Cowley AW Jr) Am J Physiol 1990 Dec;259(6 Pt 2):H1629-36 PMID: 2260689 SCOPUS ID: 2-s2.0-0025640028 12/11/1990 58 Citations

Regional autoregulatory responses during infusion of vasoconstrictor agents in conscious dogs. (Hellebrekers LJ, Liard JF, Laborde AL, Greene AS, Cowley AW Jr) Am J Physiol 1990 Oct;259(4 Pt 2):H1270-7 PMID: 2221130 SCOPUS ID: 2-s2.0-0025016252 10/11/1990 30 Citations

Atrial natriuretic peptide augments forearm capillary filtration in humans. (Groban L, Cowley AW Jr, Ebert TJ) Am J Physiol 1990 Jul;259(1 Pt 2):H258-63 PMID: 2142858 SCOPUS ID: 2-s2.0-0025118682 07/01/1990 49 Citations

Microvessel changes in hypertension measured by Griffonia simplicifolia I lectin. (Greene AS, Lombard JH, Cowley AW Jr, Hansen-Smith FM) Hypertension 1990 Jun;15(6 Pt 2):779-83 PMID: 2351431 SCOPUS ID: 2-s2.0-0025311088 06/01/1990 82 Citations

Structural changes during microvascular rarefaction in chronic hypertension. (Hansen-Smith F, Greene AS, Cowley AW Jr, Lombard JH) Hypertension 1990 Jun;15(6 Pt 2):922-8 PMID: 2351442 SCOPUS ID: 2-s2.0-0025313654 06/01/1990 78 Citations

Vasoconstriction during volume expansion is independent of central control. (Hinojosa-Laborde C, Thunhorst RL, Cowley AW Jr) Hypertension 1990 Jun;15(6 Pt 2):712-7 PMID: 2351426 SCOPUS ID: 2-s2.0-0025370609 06/01/1990 6 Citations

1/f fluctuations in arterial pressure and regulation of renal blood flow in dogs. (Marsh DJ, Osborn JL, Cowley AW Jr) Am J Physiol 1990 May;258(5 Pt 2):F1394-400 PMID: 2337155 SCOPUS ID: 2-s2.0-0025288118 05/11/1990 96 Citations

Prevention of salt angiotensin II hypertension by servo control of body water. (Krieger JE, Cowley AW Jr) Am J Physiol 1990 Apr;258(4 Pt 2):H994-1003 PMID: 2331020 SCOPUS ID: 2-s2.0-0025228566 04/11/1990 32 Citations

Role of blood volume expansion in Dahl rat model of hypertension. (Greene AS, Yu ZY, Roman RJ, Cowley AW Jr) Am J Physiol 1990 Feb;258(2 Pt 2):H508-14 PMID: 2309916 SCOPUS ID: 2-s2.0-0025329671 02/11/1990 120 Citations

Cortisol inhibition of vasopressin and ACTH responses to arterial hypotension in conscious dogs. (Raff H, Skelton MM, Cowley AW Jr) Am J Physiol 1990 Jan;258(1 Pt 2):R64-9 PMID: 2154137 SCOPUS ID: 2-s2.0-0025129094 01/11/1990 8 Citations

Role of fluid volume retention in angiotensin II salt-dependent hypertension. (Cowley AW Jr, Krieger JE) Acta Physiol Scand Suppl 1990;591:100-6 PMID: 2220402 SCOPUS ID: 2-s2.0-0025314447 01/01/1990 6 Citations

Hemodynamics and blood volume in angiotensin II salt-dependent hypertension in dogs. (Krieger JE, Roman RJ, Cowley AW Jr) Am J Physiol 1989 Nov;257(5 Pt 2):H1402-12 PMID: 2589496 SCOPUS ID: 2-s2.0-0024308828 11/11/1989 37 Citations

Effect of plasma sodium on aldosterone secretion during angiotensin II stimulation in normal humans. (Merrill DC, Ebert TJ, Skelton MM, Cowley AW Jr) Hypertension 1989 Aug;14(2):164-9 PMID: 2527200 SCOPUS ID: 2-s2.0-0024319330 08/01/1989 9 Citations

Stimulation of atrial natriuretic peptide and vasopressin during percutaneous transluminal aortic valvuloplasty. (Lewin RF, Raff H, Findling JW, Skelton MM, Cowley AW Jr, King JF, Dorros G) Am Heart J 1989 Aug;118(2):292-8 PMID: 2546414 SCOPUS ID: 2-s2.0-0024412283 08/01/1989 6 Citations

Control of blood and extracellular volume. (Cowley AW Jr, Roman RJ) Baillieres Clin Endocrinol Metab 1989 Aug;3(2):331-69 PMID: 2698141 SCOPUS ID: 2-s2.0-0024934956 08/01/1989 23 Citations

Feedback control of vasopressin and corticotrophin secretion in conscious dogs: effect of hypertonic saline. (Raff H, Skelton MM, Cowley AW Jr) J Endocrinol 1989 Jul;122(1):41-8 PMID: 2549155 SCOPUS ID: 2-s2.0-0024347595 07/01/1989 17 Citations

Hemodynamic effects of endothelin in conscious rats. (Hinojosa-Laborde C, Osborn JW Jr, Cowley AW Jr) Am J Physiol 1989 Jun;256(6 Pt 2):H1742-6 PMID: 2660597 SCOPUS ID: 2-s2.0-0024312814 06/11/1989 31 Citations

Hemodynamic, renal, and hormonal responses to incremental ANF infusions in humans. (Groban L, Ebert TJ, Kreis DU, Skelton MM, Van Wynsberghe DM, Cowley AW Jr) Am J Physiol 1989 May;256(5 Pt 2):F780-6 PMID: 2524166 SCOPUS ID: 2-s2.0-0024312721 05/11/1989 25 Citations

Effect of long-term tilt on mechanical and electrical properties of rat saphenous vein. (Monos E, Contney SJ, Cowley AW Jr, Stekiel WJ) Am J Physiol 1989 Apr;256(4 Pt 2):H1185-91 PMID: 2705557 SCOPUS ID: 2-s2.0-0024602004 04/11/1989 46 Citations

Whole body autoregulation in conscious areflexic rats during hypoxia and hyperoxia. (Hinojosa-Laborde C, Greene AS, Cowley AW Jr) Am J Physiol 1989 Apr;256(4 Pt 2):H1023-9 PMID: 2705545 SCOPUS ID: 2-s2.0-0024567010 04/11/1989 8 Citations

Blood pressure responses to cyclic blood volume changes in awake and anesthetized dogs. (Brown DR, Cowley AW Jr, Young DB) Am J Physiol 1989 Apr;256(4 Pt 2):R827-35 PMID: 2705573 SCOPUS ID: 2-s2.0-0024524544 04/11/1989

Sequential changes of cerebrospinal fluid sodium during the development of hypertension in Dahl rats. (Nakamura K, Cowley AW Jr) Hypertension 1989 Mar;13(3):243-9 PMID: 2921078 SCOPUS ID: 2-s2.0-0024594926 03/01/1989 99 Citations

Hemodynamics and microcirculatory alterations in reduced renal mass hypertension. (Lombard JH, Hinojosa-Laborde C, Cowley AW Jr) Hypertension 1989 Feb;13(2):128-38 PMID: 2914735 SCOPUS ID: 2-s2.0-0024594187 02/01/1989 70 Citations

Electrical and mechanical responses of rat saphenous vein to short-term pressure load. (Monos E, Contney SJ, Cowley AW Jr, Stekiel WJ) Am J Physiol 1989 Jan;256(1 Pt 2):H47-55 PMID: 2912197 SCOPUS ID: 2-s2.0-0024545236 01/11/1989 26 Citations

Microvascular rarefaction and tissue vascular resistance in hypertension. (Greene AS, Tonellato PJ, Lui J, Lombard JH, Cowley AW Jr) Am J Physiol 1989 Jan;256(1 Pt 2):H126-31 PMID: 2912175 SCOPUS ID: 2-s2.0-0024557970 01/11/1989 232 Citations

Pressure-diuresis in volume-expanded rats. Cortical and medullary hemodynamics. (Roman RJ, Cowley AW Jr, Garcia-Estañ J, Lombard JH) Hypertension 1988 Aug;12(2):168-76 PMID: 3410525 SCOPUS ID: 2-s2.0-0023687467 08/01/1988 141 Citations

Acute saline loading in normal and bilaterally atrial-resected conscious dogs. (Cowley AW Jr, Anderas PR, Skelton MM) Am J Physiol 1988 Jul;255(1 Pt 2):H144-52 PMID: 3293468 SCOPUS ID: 2-s2.0-0023683927 07/11/1988 19 Citations

Dynamic cardiovascular responses to infusions of atrial natriuretic factor in humans. (Ebert TJ, Skelton MM, Cowley AW Jr) Hypertension 1988 Jun;11(6 Pt 1):537-44 PMID: 2968309 SCOPUS ID: 2-s2.0-0023718654 06/01/1988 24 Citations

Autoregulation of the systemic circulation in conscious rats. (Hinojosa-Laborde C, Greene AS, Cowley AW Jr) Hypertension 1988 Jun;11(6 Pt 2):685-91 PMID: 3134305 SCOPUS ID: 2-s2.0-0023766845 06/01/1988 25 Citations

Atrial natriuretic factor attenuates carotid baroreflex-mediated cardioacceleration in humans. (Ebert TJ, Cowley AW Jr) Am J Physiol 1988 Apr;254(4 Pt 2):R590-4 PMID: 2965521 SCOPUS ID: 2-s2.0-0023942816 04/11/1988 35 Citations

Control of adrenocorticotropin secretion and adrenocortical sensitivity in neurohypophysectomized conscious dogs: effects of acute and chronic vasopressin replacement. (Raff H, Merrill DC, Skelton MM, Brownfield MS, Cowley AW Jr) Endocrinology 1988 Apr;122(4):1410-8 PMID: 2831029 SCOPUS ID: 2-s2.0-0023903554 04/01/1988 22 Citations

Association of Chairmen of Departments of Physiology annual questionnaire results. (Cowley AW Jr, Brennan J) Physiologist 1988 Apr;31(2):27-33 PMID: 3375328 SCOPUS ID: 2-s2.0-0023987692 04/01/1988

Role of vasopressin in regulation of sodium excretion. (Cowley AW Jr, Merrill DC, Smith MJ Jr, Skelton MM) Am J Med Sci 1988 Apr;295(4):308-13 PMID: 3284352 SCOPUS ID: 2-s2.0-0023915124 04/01/1988 9 Citations

Vasopressin and arterial pressure regulation. Special lecture. (Cowley AW Jr, Liard JF) Hypertension 1988 Feb;11(2 Pt 2):I25-32 PMID: 3346062 SCOPUS ID: 2-s2.0-0023941883 02/01/1988 61 Citations

Vasopressin and blood pressure regulation. (Cowley AW Jr) Clin Physiol Biochem 1988;6(3-4):150-62 PMID: 3060296 SCOPUS ID: 2-s2.0-0023943668 01/01/1988 34 Citations

Angiotensin II sensitization of aldosterone responsiveness to plasma sodium in conscious dogs. (Merrill DC, Skelton MM, Cowley AW Jr) Am J Physiol 1987 Dec;253(6 Pt 2):R832-7 PMID: 3425762 SCOPUS ID: 2-s2.0-0023552788 12/11/1987 3 Citations

Pressor response to small elevations of cerebroventricular pressure in conscious rats. (Nakamura K, Osborn JW Jr, Cowley AW Jr) Hypertension 1987 Dec;10(6):635-41 PMID: 3692574 SCOPUS ID: 2-s2.0-0023546895 12/01/1987 22 Citations

Atriopeptin III alters renal medullary hemodynamics and the pressure-diuresis response in rats. (Takezawa K, Cowley AW Jr, Skelton M, Roman RJ) Am J Physiol 1987 Jun;252(6 Pt 2):F992-1002 PMID: 2954473 SCOPUS ID: 2-s2.0-0023177960 06/11/1987 81 Citations

Hormonal responses and blood pressure maintenance in normal and hypertensive subjects during acute blood loss. (Velasquez MT, Menitove JE, Skelton MM, Cowley AW Jr) Hypertension 1987 May;9(5):423-8 PMID: 3552977 SCOPUS ID: 2-s2.0-0023220945 05/01/1987 10 Citations

Effect of AVP on pressor responses to peripheral sympathetic stimulation in the rat. (Osborn JW Jr, Liard JF, Cowley AW Jr) Am J Physiol 1987 Apr;252(4 Pt 2):H675-80 PMID: 3565586 SCOPUS ID: 2-s2.0-0023243565 04/11/1987 8 Citations

Water loading and restriction in essential hypertension. (Velasquez MT, Skelton MM, Cowley AW Jr) Hypertension 1987 Apr;9(4):407-14 PMID: 3549558 SCOPUS ID: 2-s2.0-0023142718 04/01/1987 11 Citations

Hemodynamic effects of vasopressin compared with angiotensin II in conscious rats. (Osborn JW Jr, Skelton MM, Cowley AW Jr) Am J Physiol 1987 Mar;252(3 Pt 2):H628-37 PMID: 3826404 SCOPUS ID: 2-s2.0-0023189189 03/11/1987 52 Citations

Chronic effects of vasopressin on fluid volume distribution in conscious dogs. (Merrill DC, Cowley AW Jr) Am J Physiol 1987 Jan;252(1 Pt 2):F26-31 PMID: 3812701 SCOPUS ID: 2-s2.0-0023219261 01/11/1987 8 Citations

Vasopressin responses to corticotropin releasing factor and hyperosmolality in conscious dogs. (Raff H, Skelton MM, Merrill DC, Cowley AW Jr) Am J Physiol 1986 Dec;251(6 Pt 2):R1235-9 PMID: 3024513 SCOPUS ID: 2-s2.0-0023013819 12/11/1986 18 Citations

Chronic measurement of cardiac output in unanesthetized rats using miniature thermocouples. (Osborn JW Jr, Barber BJ, Quillen EW Jr, Abram RJ, Cowley AW Jr) Am J Physiol 1986 Dec;251(6 Pt 2):H1365-72 PMID: 3789186 SCOPUS ID: 2-s2.0-0023037615 12/11/1986 15 Citations

Cardiovascular actions of vasopressin: baroreflex modulation in the conscious rat. (Webb RL, Osborn JW Jr, Cowley AW Jr) Am J Physiol 1986 Dec;251(6 Pt 2):H1244-51 PMID: 3789178 SCOPUS ID: 2-s2.0-0023028433 12/11/1986 49 Citations

Elevated plasma vasopressin (AVP) levels during resection of pheochromocytomas. (Kay J, Minkel DT, Gustafson AB, Skelton M, Cowley AW Jr, Wilson SD) Surgery 1986 Dec;100(6):1150-3 PMID: 3787473 SCOPUS ID: 2-s2.0-0022872536 12/01/1986 6 Citations

Relationship between body fluid volumes and arterial pressure. (Cowley AW Jr, Barber WJ, Lombard JH, Osborn JL, Liard JF) Fed Proc 1986 Dec;45(13):2864-70 PMID: 3536582 SCOPUS ID: 2-s2.0-0022878970 12/01/1986 28 Citations

Osmoregulation during high salt intake: relative importance of drinking and vasopressin secretion. (Cowley AW Jr, Skelton MM, Merrill DC) Am J Physiol 1986 Nov;251(5 Pt 2):R878-86 PMID: 3777216 SCOPUS ID: 2-s2.0-0023035922 11/11/1986 13 Citations

Hemodynamic effects of infused arginine vasopressin in congestive heart failure. (Goldsmith SR, Francis GS, Cowley AW Jr, Goldenberg IF, Cohn JN) J Am Coll Cardiol 1986 Oct;8(4):779-83 PMID: 3760354 10/01/1986

Influence of endogenous opioids on the response of selected hormones to exercise in humans. (Farrell PA, Gustafson AB, Garthwaite TL, Kalkhoff RK, Cowley AW Jr, Morgan WP) J Appl Physiol (1985) 1986 Sep;61(3):1051-7 PMID: 3759744 SCOPUS ID: 2-s2.0-0022448439 09/01/1986 69 Citations

Arginine vasopressin and the renal response to water loading in congestive heart failure. (Goldsmith SR, Francis GS, Cowley AW Jr) Am J Cardiol 1986 Aug 01;58(3):295-9 PMID: 3739918 SCOPUS ID: 2-s2.0-0022547140 08/01/1986 99 Citations

Vagal regulation of arginine vasopressin in conscious dogs. (Morita H, Manders WT, Skelton MM, Cowley AW Jr, Vatner SF) Am J Physiol 1986 Jul;251(1 Pt 2):H19-23 PMID: 3728695 SCOPUS ID: 2-s2.0-0022470618 07/11/1986 11 Citations

Humoral control of water and electrolyte excretion during water restriction. (Merrill DC, Skelton MM, Cowley AW Jr) Kidney Int 1986 Jun;29(6):1152-61 PMID: 3528610 SCOPUS ID: 2-s2.0-0022620266 06/01/1986 17 Citations

Vasopressin reduces cardiac function and augments cardiopulmonary baroreflex resistance increases in man. (Ebert TJ, Cowley AW Jr, Skelton M) J Clin Invest 1986 Apr;77(4):1136-42 PMID: 3514673 PMCID: PMC424448 SCOPUS ID: 2-s2.0-0022549988 04/01/1986 56 Citations

Are hypertensive effects of aldosterone, angiotensin, vasopressin, and norepinephrine chronically additive? (Cowley AW Jr, Skelton MM, Merrill DC) Hypertension 1986 Apr;8(4):332-43 PMID: 3514449 SCOPUS ID: 2-s2.0-0022501142 04/01/1986 8 Citations

Chronic effects of vasopressin on plasma renin activity in sodium-restricted dogs. (Merrill DC, Cowley AW Jr) Am J Physiol 1986 Mar;250(3 Pt 2):F460-9 PMID: 3513620 SCOPUS ID: 2-s2.0-0022539612 03/11/1986 10 Citations

Vasopressin excess: relative contribution of volume retention versus direct actions on renin secretion and sodium excretion. (Cowley AW Jr, Merrill DC, Skelton MM, Smith MJ Jr) J Cardiovasc Pharmacol 1986;8 Suppl 7:S66-9 PMID: 2434776 SCOPUS ID: 2-s2.0-0022895269 01/01/1986 5 Citations

Hemodynamic effects of neurohypophyseal peptides with antidiuretic activity in dogs. (Schwartz J, Liard JF, Ott C, Cowley AW Jr) Am J Physiol 1985 Nov;249(5 Pt 2):H1001-8 PMID: 3840655 SCOPUS ID: 2-s2.0-0022152966 11/11/1985 41 Citations

Control of ACTH and vasopressin in neurohypophysectomized conscious dogs. (Raff H, Merrill D, Skelton M, Cowley AW Jr) Am J Physiol 1985 Aug;249(2 Pt 2):R281-4 PMID: 2992297 SCOPUS ID: 2-s2.0-0022103073 08/11/1985 13 Citations

Effects of baroreceptor denervation on volume loading hypertension in anephric dogs. (Manning RD Jr, Cowley AW Jr, Coleman TG) Hypertension 1985;7(4):562-8 PMID: 4007991 SCOPUS ID: 2-s2.0-0021815114 07/01/1985 2 Citations

Reflex control of osmotically stimulated vasopressin in normal humans. (Goldsmith SR, Cowley AW Jr, Francis GS, Cohn JN) Am J Physiol 1985 Jun;248(6 Pt 2):R660-3 PMID: 4003575 SCOPUS ID: 2-s2.0-0022083833 06/11/1985 14 Citations

Sex differences in the endocrine predictors of essential hypertension. Vasopressin versus renin. (Cowley AW Jr, Skelton MM, Velasquez MT) Hypertension 1985;7(3 Pt 2):I151-60 PMID: 3888837 SCOPUS ID: 2-s2.0-0021874115 05/01/1985 34 Citations

Abnormal pressure-diuresis-natriuresis response in spontaneously hypertensive rats. (Roman RJ, Cowley AW Jr) Am J Physiol 1985 Feb;248(2 Pt 2):F199-205 PMID: 3970210 SCOPUS ID: 2-s2.0-0021965652 02/11/1985 161 Citations

Characterization of a new model for the study of pressure-natriuresis in the rat. (Roman RJ, Cowley AW Jr) Am J Physiol 1985 Feb;248(2 Pt 2):F190-8 PMID: 3970209 SCOPUS ID: 2-s2.0-0021932716 02/11/1985 199 Citations

Long-term influence of vasopressin on the control of arterial blood pressure independent of volume changes. (Cowley AW Jr, Skelton MM, Merrill DC) J Hypertens Suppl 1984 Dec;2(3):S337-9 PMID: 6599677 SCOPUS ID: 2-s2.0-0021672731 12/01/1984 6 Citations

Osmotic control of vasopressin with chronically altered volume states in anephric dogs. (Quillen EW Jr, Skelton MM, Rubin J, Cowley AW Jr) Am J Physiol 1984 Sep;247(3 Pt 1):E355-61 PMID: 6476113 SCOPUS ID: 2-s2.0-0021484981 09/11/1984 6 Citations

Long-term blood pressure and metabolic effects of vasopressin with servo-controlled fluid volume. (Cowley AW Jr, Merrill DC, Quillen EW Jr, Skelton MM) Am J Physiol 1984 Sep;247(3 Pt 2):R537-45 PMID: 6383081 SCOPUS ID: 2-s2.0-0021487509 09/11/1984 30 Citations

Effect of increased intracardiac and arterial pressure on plasma vasopressin in humans. (Goldsmith SR, Cowley AW Jr, Francis GS, Cohn JN) Am J Physiol 1984 May;246(5 Pt 2):H647-51 PMID: 6720976 SCOPUS ID: 2-s2.0-0021435083 05/11/1984 35 Citations

Assessment of the contributions of autoregulatory mechanisms to the antihypertensive actions of beta-adrenergic therapy. (Cowley AW Jr) Hypertension 1984;6(2 Pt 1):137-9 PMID: 6144630 SCOPUS ID: 2-s2.0-0021235417 03/01/1984 5 Citations

Influence of vasopressin and angiotensin on baroreflexes in the dog. (Cowley AW Jr, Merrill D, Osborn J, Barber BJ) Circ Res 1984 Feb;54(2):163-72 PMID: 6692503 SCOPUS ID: 2-s2.0-0021329553 02/01/1984 59 Citations

Influence of daily sodium intake on vasopressin secretion and drinking in dogs. (Cowley AW Jr, Skelton MM, Merrill DC, Quillen EW Jr, Switzer SJ) Am J Physiol 1983 Dec;245(6):R860-72 PMID: 6362437 SCOPUS ID: 2-s2.0-0020986276 12/11/1983 24 Citations

Role of vasopressin in cardiovascular regulation. (Cowley AW Jr, Quillen EQ Jr, Skelton MM) Fed Proc 1983 Dec;42(15):3170-6 PMID: 6641951 SCOPUS ID: 2-s2.0-0021040826 12/01/1983 94 Citations

Impaired response of plasma vasopressin to orthostatic stress in patients with congestive heart failure. (Goldsmith SR, Francis GS, Levine TB, Cowley AW Jr, Cohn JN) J Am Coll Cardiol 1983 Dec;2(6):1080-3 PMID: 6355240 12/01/1983

Increased plasma arginine vasopressin levels in patients with congestive heart failure. (Goldsmith SR, Francis GS, Cowley AW Jr, Levine TB, Cohn JN) J Am Coll Cardiol 1983 Jun;1(6):1385-90 PMID: 6343460 06/01/1983

Renal dysfunction in essential hypertension--implications of experimental studies. (Cowley AW Jr, Roman RJ) Am J Nephrol 1983;3(2-3):59-72 PMID: 6346877 SCOPUS ID: 2-s2.0-0020962337 03/01/1983 15 Citations

Influence of volume changes on osmolality-vasopressin relationships in conscious dogs. (Quillen EW Jr, Cowley AW Jr) Am J Physiol 1983 Jan;244(1):H73-9 PMID: 6849407 SCOPUS ID: 2-s2.0-0020696195 01/11/1983 56 Citations

Vasopressin vascular and reflex effects--a theoretical analysis. (Cowley AW Jr, Barber BJ) Prog Brain Res 1983;60:415-24 PMID: 6665153 SCOPUS ID: 2-s2.0-0020989616 01/01/1983 25 Citations

Vasopressin and cardiovascular regulation. (Cowley AW Jr) Int Rev Physiol 1982;26:189-242 PMID: 7107151 SCOPUS ID: 2-s2.0-0020082675 01/01/1982 79 Citations

Is vasopressin an important hypertensive hormone? (Lohmeier TE, Smith MJ Jr, Cowley AW Jr, Manning RD Jr, Guyton AC) Hypertension 1981;3(4):416-25 PMID: 7309205 SCOPUS ID: 2-s2.0-0019720753 07/01/1981 34 Citations

Vasopressin elevation in essential hypertension and increased responsiveness to sodium intake. (Cowley AW Jr, Cushman WC, Quillen EW Jr, Skelton MM, Langford HG) Hypertension 1981;3(3 Pt 2):I93-100 PMID: 7262983 SCOPUS ID: 2-s2.0-0019795377 05/01/1981 133 Citations

Vasopressin, fluid, and electrolyte response to chronic angiotensin II infusion. (Cowley AW Jr, Switzer SJ, Skelton MM) Am J Physiol 1981 Mar;240(3):R130-8 PMID: 7212084 SCOPUS ID: 2-s2.0-0019542819 03/11/1981 39 Citations

An inexpensive pressure telemetry system. (Barber BJ, Quillen EW Jr, Cowley AW Jr) Am J Physiol 1980 Oct;239(4):H570-H572 PMID: 7425148 SCOPUS ID: 2-s2.0-0019069736 10/11/1980 2 Citations

Role of the renin-angiotensin system in prostaglandin E2-induced hypertension. (Hockel GM, Cowley AW Jr) Hypertension 1980;2(4):529-37 PMID: 6995293 SCOPUS ID: 2-s2.0-0019133649 07/01/1980 7 Citations

The concept of autoregulation of total blood flow and its role in hypertension. (Cowley AW Jr) Am J Med 1980 Jun;68(6):906-16 PMID: 7386494 SCOPUS ID: 2-s2.0-0018826194 06/01/1980 46 Citations

Evidence and quantification of the vasopressin arterial pressure control system in the dog. (Cowley AW Jr, Switzer SJ, Guinn MM) Circ Res 1980 Jan;46(1):58-67 PMID: 7349918 SCOPUS ID: 2-s2.0-0018881224 01/01/1980 132 Citations

Effect of chronic intrarenal prostaglandin E2 infusion and angiotensin II blockade on arterial pressure in the dog. (Hockel GM, Cowley AW Jr) Adv Prostaglandin Thromboxane Res 1980;7:1061-5 PMID: 6989177 SCOPUS ID: 2-s2.0-0018880345 01/01/1980 3 Citations

Water diuretic and natriuretic effect of clonidine in the rat. (Roman RJ, Cowley AW Jr, Lechene C) J Pharmacol Exp Ther 1979 Nov;211(2):385-93 PMID: 501569 SCOPUS ID: 2-s2.0-0018614278 11/01/1979 56 Citations

Changes in renal vascular sensitivity and arterial pressure associated with sodium intake during long-term intrarenal norepinephrine infusion in dogs. (Cowley AW Jr, Lohmeier TE) Hypertension 1979;1(6):549-58 PMID: 396248 SCOPUS ID: 2-s2.0-0018535717 11/01/1979 58 Citations

Prostaglandin E2-induced hypertension in conscious dogs. (Hockel GM, Cowley AW Jr) Am J Physiol 1979 Oct;237(4):H449-54 PMID: 495730 SCOPUS ID: 2-s2.0-0018533513 10/11/1979 24 Citations

Hypertensive and renal effects of chronic low level intrarenal angiotensin infusion in the dog. (Lohmeier TE, Cowley AW Jr) Circ Res 1979 Feb;44(2):154-60 PMID: 761300 SCOPUS ID: 2-s2.0-0018341459 02/01/1979 60 Citations

Subpressor angiotensin infusion, renal sodium handling, and salt-induced hypertension in the dog. (DeClue JW, Guyton AC, Cowley AW Jr, Coleman TG, Norman RA Jr, McCaa RE) Circ Res 1978 Oct;43(4):503-12 PMID: 688554 10/01/1978

Failure of chronic aldosterone infusion to increase arterial pressure in dogs with angiotensin-induced hypertension. (Lohmeier TE, Cowley AW Jr, DeClue JW, Guyton AC) Circ Res 1978 Sep;43(3):381-90 PMID: 679421 SCOPUS ID: 2-s2.0-0018183912 09/01/1978 20 Citations

The relationship between body fluid volume, sodium ion concentration, and sensitivity to pressor effect of angiotensin II in dogs. (Cowley AW Jr, Lohmeier TE) Circ Res 1978 Apr;42(4):503-11 PMID: 630667 SCOPUS ID: 2-s2.0-0018178214 04/01/1978 9 Citations

Perspective on the physiology of hypertension. (Cowley AW Jr) Cardiovasc Clin 1978;9(1):1-22 PMID: 352514 SCOPUS ID: 2-s2.0-0018199484 01/01/1978 4 Citations

Effects of endogenous angiotensin II on renal sodium excretion and renal hemodynamics. (Lohmeier TE, Cowley AW Jr, Trippodo NC, Hall JE, Guyton AC) Am J Physiol 1977 Nov;233(5):F388-95 PMID: 920808 SCOPUS ID: 2-s2.0-0017655826 11/11/1977 70 Citations

Intrarenal control of electrolyte excretion by angiotensin II. (Hall JE, Guyton AC, Trippodo NC, Lohmeier TE, McCaa RE, Cowley AW Jr) Am J Physiol 1977 Jun;232(6):F538-44 PMID: 879288 SCOPUS ID: 2-s2.0-0017735970 06/11/1977 77 Citations

Dissociation of renal blood flow and filtration rate autoregulation by renin depletion. (Hall JE, Guyton AC, Cowley AW Jr) Am J Physiol 1977 Mar;232(3):F215-21 PMID: 842668 SCOPUS ID: 2-s2.0-0017328094 03/11/1977 91 Citations

Angiotensin II antagonists in dehydrated rabbits without baroreceptor reflexes. (Trippodo NC, Coleman TG, Cowley AW Jr, Guyton AC) Am J Physiol 1977 Feb;232(2):H110-3 PMID: 842642 SCOPUS ID: 2-s2.0-0017358241 02/11/1977 8 Citations

Feedback mechanisms of arterial pressure control. (Coleman TG, Guyton AC, Cowley AW Jr, Bower JD, Norman RA Jr, Manning RD Jr) Contrib Nephrol 1977;8:5-12 PMID: 891217 SCOPUS ID: 2-s2.0-0017346707 01/01/1977 8 Citations

Synthesis of endocrine control in hypertension. (Guyton AC, Cowley AW Jr, Young DB, DeClue JW, Manning RD Jr, Fagard R, McCaa RE, Trippodo NC) Clin Sci Mol Med Suppl 1976 Dec;3:319s-320s PMID: 1071636 SCOPUS ID: 2-s2.0-0017270841 12/11/1976 3 Citations

Renal responses to slight elevations of renal arterial plasma angiotensin II concentration in dogs. (Fagard RH, Cowley AW Jr, Navar LG, Langford HG, Guyton AC) Clin Exp Pharmacol Physiol 1976;3(6):531-8 PMID: 1009691 SCOPUS ID: 2-s2.0-0017092923 11/11/1976 26 Citations

Integration and control of circulatory function. (Guyton AC, Cowley AW Jr, Young DB, Coleman TG, Hall JE, DeClue JW) Int Rev Physiol 1976;9:341-85 PMID: 135739 SCOPUS ID: 2-s2.0-0017278155 01/01/1976 49 Citations

Quantitative analysis of the acute response to haemorrhage of the renin-angiotensin-vasoconstrictor feedback loop in areflexic dogs. (Brough RB Jr, Cowley AW Jr, Guyton AC) Cardiovasc Res 1975 Nov;9(6):722-33 PMID: 1203912 SCOPUS ID: 2-s2.0-85047679771 11/11/1975 16 Citations

Angiotensin and the hemodynamics of chronic salt deprivation. (Coleman TG, Cowley AW Jr, Guyton AC) Am J Physiol 1975 Jul;229(1):167-71 PMID: 167593 SCOPUS ID: 2-s2.0-0016763822 07/11/1975 20 Citations

Baroreceptor reflex effects on transient and steady-state hemodynamics of salt-loading hypertension in dogs. (Cowley AW Jr, Guyton AC) Circ Res 1975 Apr;36(4):536-46 PMID: 1116246 SCOPUS ID: 2-s2.0-0016612794 04/11/1975 49 Citations

Renin, aldosterone, body fluid volumes, and the baroreceptor reflex in the development and reversal of Goldblatt hypertension in conscious dogs. (Liard JF, Cowley AW Jr, McCaa RE, McCaa CS, Guyton AC) Circ Res 1974 Apr;34(4):549-60 PMID: 4857066 04/01/1974

Interaction of vasopressin and the baroreceptor reflex system in the regulation of arterial blood pressure in the dog. (Cowley AW Jr, Monos E, Guyton AC) Circ Res 1974 Apr;34(4):505-14 PMID: 4826927 SCOPUS ID: 2-s2.0-0016228216 04/01/1974 253 Citations

Hypertension: a disease of abnormal circulatory control. (Guyton AC, Cowley AW Jr, Coleman TG, DeClue JW, Norman RA, Manning RD) Chest 1974 Mar;65(3):328-38 PMID: 4360524 SCOPUS ID: 2-s2.0-0015975186 03/01/1974 17 Citations

Dynamic functions of angiotensin in hypertension: renal effects as the basic cause of chronic hypertension. (Guyton AC, Cowley AW Jr, Fagard R, Langford HG, McCaa RE, DeClue JW, Coleman TG, Barnes GE) Acta Physiol Lat Am 1974;24(5):592-5 PMID: 4377512 SCOPUS ID: 2-s2.0-0016324387 01/01/1974 1 Citation

Influence of acute stimuli on plasma aldosterone concentration in anephric man and kidney allograft recipients. (McCaa RE, Read VH, Cowley AW Jr, Bower JD, Smith GV, McCaa CS) Circ Res 1973 Sep;33(3):313-22 PMID: 4355718 09/01/1973

Role of baroreceptor reflex in daily control of arterial blood pressure and other variables in dogs. (Cowley AW Jr, Liard JF, Guyton AC) Circ Res 1973 May;32(5):564-76 PMID: 4713198 SCOPUS ID: 2-s2.0-0015624081 05/01/1973 465 Citations

Stimulation of aldosterone secretion by hemorrhage in dogs after nephrectomy and decapitation. (McCaa RE, McCaa CS, Cowley AW Jr, Ott CE, Guyton AC) Circ Res 1973 Mar;32(3):356-62 PMID: 4347959 SCOPUS ID: 2-s2.0-0015594767 03/01/1973 13 Citations

Systems analysis of arterial pressure regulation and hypertension. (Guyton AC, Coleman TG, Cowley AW Jr, Liard JF, Norman RA Jr, Manning RD Jr) Ann Biomed Eng 1972 Dec;1(2):254-81 PMID: 4358506 SCOPUS ID: 2-s2.0-0015436650 12/01/1972 96 Citations

Quantification of intermediate steps in the renin-angiotensin-vasoconstrictor feedback loop in the dog. (Cowley AW Jr, Guyton AC) Circ Res 1972 May;30(5):557-66 PMID: 4337381 SCOPUS ID: 2-s2.0-0015335015 05/01/1972 21 Citations

Heart rate as a determinant of cardiac output in dogs with arteriovenous fistula. (Cowley AW Jr, Guyton AC) Am J Cardiol 1971 Sep;28(3):321-5 PMID: 5155759 SCOPUS ID: 2-s2.0-0015113304 09/01/1971 28 Citations

The effect of diazoxide on coronary blood flow. (Scott JC, Cowley AW Jr) Am J Cardiol 1969 Dec;24(6):865-9 PMID: 5360240 SCOPUS ID: 2-s2.0-0014635499 12/01/1969 11 Citations

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Allen W. Cowley PhD

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Publications (382)