Medical College of Wisconsin
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Amy W. Hudson PhD

Amy W. Hudson PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Microbiology and Immunology

Member of the Cancer Center


Research Experience

  • Antigen Presentation
  • Exanthema Subitum
  • Genes, MHC Class I
  • Herpesvirus 6, Human
  • Herpesvirus 7, Human
  • insulin-responsive glucose transport
  • synaptic vesicle recycling
  • viral immune evasion
  • HHV-6
  • HHV-7
  • human CD45
  • membrane trafficking
  • Publications (18)

  • HHV-7 U21 exploits Golgi quality control carriers to reroute class I MHC molecules to lysosomes. (Dirck AT, Whyte ML, Hudson AW) Mol Biol Cell 2020 02 01;31(3):196-208 PMID: 31851583 PMCID: PMC7001482 SCOPUS ID: 2-s2.0-85081146090 12/19/2019    
  • Adoptively transferred Vγ9Vδ2 T cells show potent antitumor effects in a preclinical B cell lymphomagenesis model. (Zumwalde NA, Sharma A, Xu X, Ma S, Schneider CL, Romero-Masters JC, Hudson AW, Gendron-Fitzpatrick A, Kenney SC, Gumperz JE) JCI Insight 2017 Jul 06;2(13) PMID: 28679955 PMCID: PMC5499361 SCOPUS ID: 2-s2.0-85045321193 07/07/2017       27 Citations
  • Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus. (Sturgill ER, Malouli D, Hansen SG, Burwitz BJ, Seo S, Schneider CL, Womack JL, Verweij MC, Ventura AB, Bhusari A, Jeffries KM, Legasse AW, Axthelm MK, Hudson AW, Sacha JB, Picker LJ, Früh K) PLoS Pathog 2016 08;12(8):e1005868 PMID: 27580123 PMCID: PMC5006984 SCOPUS ID: 2-s2.0-84984830187 09/01/2016       18 Citations
  • Roseoloviruses and their modulation of host defenses. (Hudson AW) Curr Opin Virol 2014 Dec;9:178-87 PMID: 25462451 SCOPUS ID: 2-s2.0-84915759618 12/03/2014       10 Citations
  • Adaptor protein complexes AP-1 and AP-3 are required by the HHV-7 Immunoevasin U21 for rerouting of class I MHC molecules to the lysosomal compartment. (Kimpler LA, Glosson NL, Downs D, Gonyo P, May NA, Hudson AW) PLoS One 2014;9(6):e99139 PMID: 24901711 PMCID: PMC4047081 SCOPUS ID: 2-s2.0-84902477273 06/06/2014       3 Citations
  • Human herpesvirus 7 U21 tetramerizes to associate with class I major histocompatibility complex molecules. (May NA, Wang Q, Balbo A, Konrad SL, Buchli R, Hildebrand WH, Schuck P, Hudson AW) J Virol 2014 Mar;88(6):3298-308 PMID: 24390327 PMCID: PMC3957921 SCOPUS ID: 2-s2.0-84894543495 01/07/2014       9 Citations
  • Expression of CD1c enhances human invariant NKT cell activation by α-GalCer. (Fox LM, Miksanek J, May NA, Scharf L, Lockridge JL, Veerapen N, Besra GS, Adams EJ, Hudson AW, Gumperz JE) Cancer Immun 2013;13:9 PMID: 23885215 PMCID: PMC3721260 SCOPUS ID: 2-s2.0-84879033899 07/26/2013       8 Citations
  • The human herpesvirus-7 (HHV-7) U21 immunoevasin subverts NK-mediated cytoxicity through modulation of MICA and MICB. (Schneider CL, Hudson AW) PLoS Pathog 2011 Nov;7(11):e1002362 PMID: 22102813 PMCID: PMC3213103 SCOPUS ID: 2-s2.0-81755166703 11/22/2011       29 Citations
  • Insight into the mechanism of human herpesvirus 7 U21-mediated diversion of class I MHC molecules to lysosomes. (Glosson NL, Gonyo P, May NA, Schneider CL, Ristow LC, Wang Q, Hudson AW) J Biol Chem 2010 Nov 19;285(47):37016-29 PMID: 20833720 PMCID: PMC2978630 SCOPUS ID: 2-s2.0-78449233108 09/14/2010       11 Citations
  • Human herpesvirus 7 u21 downregulates classical and nonclassical class I major histocompatibility complex molecules from the cell surface. (May NA, Glosson NL, Hudson AW) J Virol 2010 Apr;84(8):3738-51 PMID: 20106916 PMCID: PMC2849505 SCOPUS ID: 2-s2.0-77950482035 01/29/2010       16 Citations
  • Human herpesvirus-6A and -6B encode viral immunoevasins that downregulate class I MHC molecules. (Glosson NL, Hudson AW) Virology 2007 Aug 15;365(1):125-35 PMID: 17467766 SCOPUS ID: 2-s2.0-34250165758 05/01/2007       37 Citations
  • Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein. (Cooper EM, Hudson AW, Amos J, Wagstaff J, Howley PM) J Biol Chem 2004 Sep 24;279(39):41208-17 PMID: 15263005 SCOPUS ID: 2-s2.0-4644295494 07/21/2004       66 Citations
  • The ER-lumenal domain of the HHV-7 immunoevasin U21 directs class I MHC molecules to lysosomes. (Hudson AW, Blom D, Howley PM, Ploegh HL) Traffic 2003 Dec;4(12):824-37 PMID: 14617346 SCOPUS ID: 2-s2.0-0348013275 11/18/2003       25 Citations
  • The cell biology of antigen presentation. (Hudson AW, Ploegh HL) Exp Cell Res 2002 Jan 01;272(1):1-7 PMID: 11740859 SCOPUS ID: 2-s2.0-0036059818 12/13/2001       28 Citations
  • A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes. (Hudson AW, Howley PM, Ploegh HL) J Virol 2001 Dec;75(24):12347-58 PMID: 11711625 PMCID: PMC116131 SCOPUS ID: 2-s2.0-0035201673 11/17/2001       43 Citations
  • Identification of a nonneuronal isoform of synaptotagmin. (Hudson AW, Birnbaum MJ) Proc Natl Acad Sci U S A 1995 Jun 20;92(13):5895-9 PMID: 7597049 PMCID: PMC41608 SCOPUS ID: 2-s2.0-0029036903 06/20/1995       74 Citations
  • Targeting of the "insulin-responsive" glucose transporter (GLUT4) to the regulated secretory pathway in PC12 cells. (Hudson AW, Fingar DC, Seidner GA, Griffiths G, Burke B, Birnbaum MJ) J Cell Biol 1993 Aug;122(3):579-88 PMID: 8335686 PMCID: PMC2119662 SCOPUS ID: 2-s2.0-0027184471 08/01/1993       53 Citations
  • Isoform-specific subcellular targeting of glucose transporters in mouse fibroblasts. (Hudson AW, Ruiz M, Birnbaum MJ) J Cell Biol 1992 Feb;116(3):785-97 PMID: 1309819 PMCID: PMC2289322 SCOPUS ID: 2-s2.0-0026596043 02/01/1992       76 Citations
  • Last update: 08/17/2020
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