Medical College of Wisconsin
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Anupama Nair

Postdoctoral Researcher 3

Institution: Medical College of Wisconsin
Department: Obstetrics and Gynecology
Division: Obstetrics and Gynecology Research and Advanced Education

Research Areas of Interest

  • Biomedical Research
  • Lymphocytes, Tumor-Infiltrating
  • Ovarian Neoplasms

    • Research Experience

  • Apoptosis
  • Breast Neoplasms
  • Cell Line
  • Diabetic Cardiomyopathies
  • Enzyme-Linked Immunosorbent Assay
  • Heart
  • Insulin Resistance
  • Metformin
  • Microscopy, Confocal
  • Microscopy, Fluorescence
  • Mitochondria
  • Ovarian Neoplasms
  • RNA-Binding Proteins
  • Rats
  • Reactive Oxygen Species
  • T-Lymphocytes

    • Methodologies and Techniques

  • Blotting, Western
  • Chromatin Immunoprecipitation
  • Fluorescent Antibody Technique
  • Immunohistochemistry
  • Immunoprecipitation
  • Microscopy, Fluorescence
  • Real-Time Polymerase Chain Reaction
  • Reverse Transcriptase Polymerase Chain Reaction

    • Leadership Positions

  • Was a PI of a project granted by AHW (January 1st-December 31st, 2024

    • MCW Program / Core Facilities

  • CRI Leica confocal image, MACC Fund research hypoxia chamber, VBRI flow cytometry

    • Publications (15)

  • Ferulic acid attenuates high glucose-induced MAM alterations via PACS2 (P Salin Raj, A Nair, MR Preetha Rani, K Rajankutty, S Ranjith, KG Raghu) International Journal of Cardiology 6 02/15/2025    
  • Bilobalide safeguards 3T3-L1 adipocytes from hypoxia through protecting mitochondrial bioenergetics, biogenesis and dynamics (A Priyanka, Anupama Nair, SS Anusree, VM Nisha, KG Raghu) RSC Advances 02/15/2025    
  • Vanillic acid mitigates hyperinsulinemia induced ER stress mediated altered calcium homeostasis, MAMs distortion and surplus lipogenesis in HepG2 cells. (Mohan S, Nair A, Poornima MS, Raghu KG) Chem Biol Interact 2023 Apr 25;375:110365 PMID: 36764371 SCOPUS ID: 2-s2.0-85149894533 02/11/2023       14 Citations
  • Ferulic acid attenuates high glucose-induced MAM alterations via PACS2/IP3R2/FUNDC1/VDAC1 pathway activating proapoptotic proteins and ameliorates cardiomyopathy in diabetic rats. (Salin Raj P, Nair A, Preetha Rani MR, Rajankutty K, Ranjith S, Raghu KG) Int J Cardiol 2023 Feb 01;372:101-109 PMID: 36481261 SCOPUS ID: 2-s2.0-85144358133 12/09/2022       33 Citations
  • Cinnamic acid is beneficial to diabetic cardiomyopathy via its cardioprotective, anti-inflammatory, anti-dyslipidemia, and antidiabetic properties. (Nair A, Preetha Rani MR, Salin Raj P, Ranjit S, Rajankutty K, Raghu KG) J Biochem Mol Toxicol 2022 Dec;36(12):e23215 PMID: 36117386 SCOPUS ID: 2-s2.0-85138255967 09/20/2022       31 Citations
  • In vitro and in vivo studies reveal the beneficial effects of chlorogenic acid against ER stress mediated ER-phagy and associated apoptosis in the heart of diabetic rat. (Preetha Rani MR, Salin Raj P, Nair A, Ranjith S, Rajankutty K, Raghu KG) Chem Biol Interact 2022 Jan 05;351:109755 PMID: 34801538 SCOPUS ID: 2-s2.0-85120420272 11/22/2021       45 Citations
  • Corrigendum to "Chlorogenic acid attenuates glucotoxicity in H9c2 cells via inhibition of glycation and PKC α upregulation and safeguarding innate antioxidant status" [Biomed. Pharmacother. 100 (2018) 467-477]. (M R PR, Nair A, Mohan S, K G R) Biomed Pharmacother 2021 Jan;133:111071 PMID: 33298336 SCOPUS ID: 2-s2.0-85097741596 12/11/2020    
  • Pretreatment of Tribulus terrestris L. causes anti-ischemic cardioprotection through MAPK mediated anti-apoptotic pathway in rat. (Reshma PL, Binu P, Anupama N, Vineetha RC, Abhilash S, Nair RH, Raghu KG) Biomed Pharmacother 2019 Mar;111:1342-1352 PMID: 30841448 SCOPUS ID: 2-s2.0-85059958819 03/08/2019       20 Citations
  • Glucotoxicity results in apoptosis in H9c2 cells via alteration in redox homeostasis linked mitochondrial dynamics and polyol pathway and possible reversal with cinnamic acid. (Anupama N, Preetha Rani MR, Shyni GL, Raghu KG) Toxicol In Vitro 2018 Dec;53:178-192 PMID: 30144576 SCOPUS ID: 2-s2.0-85052621776 08/26/2018       20 Citations
  • Chlorogenic acid attenuates glucotoxicity in H9c2 cells via inhibition of glycation and PKC α upregulation and safeguarding innate antioxidant status. (Preetha Rani MR, Anupama N, Sreelekshmi M, Raghu KG) Biomed Pharmacother 2018 Apr;100:467-477 PMID: 29477910 SCOPUS ID: 2-s2.0-85042390449 02/27/2018       36 Citations
  • Significance of mitochondria on cardiometabolic syndromes. (Anupama N, Sindhu G, Raghu KG) Fundam Clin Pharmacol 2018 Aug;32(4):346-356 PMID: 29453877 SCOPUS ID: 2-s2.0-85046267771 02/18/2018       12 Citations
  • Development of insulin resistance through sprouting of inflammatory markers during hypoxia in 3T3-L1 adipocytes and amelioration with curcumin. (Priyanka A, Shyni GL, Anupama N, Raj PS, Anusree SS, Raghu KG) Eur J Pharmacol 2017 Oct 05;812:73-81 PMID: 28684236 SCOPUS ID: 2-s2.0-85021958665 07/08/2017       22 Citations
  • Polyphenol rich ethanolic extract from Boerhavia diffusa L. mitigates angiotensin II induced cardiac hypertrophy and fibrosis in rats. (A P, Varghese MV, S A, P SR, Mathew AK, Nair A, Nair RH, K G R) Biomed Pharmacother 2017 Mar;87:427-436 PMID: 28068633 SCOPUS ID: 2-s2.0-85008413219 01/10/2017       36 Citations
  • Symplocos cochinchinensis enhances insulin sensitivity via the down regulation of lipogenesis and insulin resistance in high energy diet rat model. (Antu KA, Riya MP, Nair A, Mishra A, Srivastava AK, Raghu KG) J Ethnopharmacol 2016 Dec 04;193:500-509 PMID: 27686268 SCOPUS ID: 2-s2.0-84991736346 10/01/2016       20 Citations
  • Bilobalide safeguards 3T3-L1 adipocytes from hypoxia through protecting mitochondrial bioenergetics, biogenesis and dynamics (Priyanka A, Nair A, Anusree SS, Nisha VM, Raghu KG) Rsc Advances 2016;6(116):114969-114979 SCOPUS ID: 2-s2.0-85006355523 01/01/2016       1 Citation
    • Last update: 02/03/2026