Medical College of Wisconsin
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Bakhtiyor Nosirov

Bakhtiyor Nosirov profile photo picture

Research Scientist I

Institution: Medical College of Wisconsin
Department: Data Science Institute
Division: Biostatistics
Program: Research

Research Areas of Interest

  • Bioinformatics, Computational Biology, Machine learning & AI

    • Publications (10)

  • Integrated single-cell analysis reveals distinct epigenetic-regulated cancer cell states and a heterogeneity-guided core signature in tamoxifen-resistant breast cancer. (Fang K, Ohihoin AG, Liu T, Choppavarapu L, Nosirov B, Wang Q, Yu XZ, Kamaraju S, Leone G, Jin VX) Genome Med 2024 Nov 18;16(1):134 PMID: 39558215 PMCID: PMC11572372 SCOPUS ID: 2-s2.0-85209564467 11/19/2024       13 Citations
  • Adenoviral delivery of the CIITA transgene induces T-cell-mediated killing in glioblastoma organoids. (Salvato I, Klein E, Poli A, Rezaeipour M, Ermini L, Nosirov B, Lipsa A, Oudin A, Baus V, Dore GM, Cosma A, Golebiewska A, Marchini A, Niclou SP) Mol Oncol 2025 Mar;19(3):682-697 PMID: 39535369 PMCID: PMC11887676 SCOPUS ID: 2-s2.0-85209063048 11/13/2024    
  • Patient-based multilevel transcriptome exploration highlights relevant chemokines and chemokine receptor axes in glioblastoma. (D'Uonnolo G, Isci D, Nosirov B, Kuppens A, Wantz M, Nazarov PV, Golebiewska A, Rogister B, Chevigné A, Neirinckx V, Szpakowska M) Comput Biol Med 2024 Nov;182:109197 PMID: 39353298 SCOPUS ID: 2-s2.0-85205226198 10/03/2024    
  • Most accurate mutations in SARS-CoV-2 genomes identified in Uzbek patients show novel amino acid changes. (Ayubov MS, Mirzakhmedov MK, Yusupov AN, Asrorov AM, Nosirov BV, Usmanov DE, Shermatov SE, Ubaydullaeva KA, Abdukarimov A, Buriev ZT, Abdurakhmonov IY) Front Med (Lausanne) 2024;11:1401655 PMID: 38882660 PMCID: PMC11176497 SCOPUS ID: 2-s2.0-85195844418 06/17/2024    
  • Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells. (Okumura T, Raja Xavier JP, Pasternak J, Yang Z, Hang C, Nosirov B, Singh Y, Admard J, Brucker SY, Kommoss S, Takeda S, Staebler A, Lang F, Salker MS) Int J Mol Sci 2024 Mar 25;25(7) PMID: 38612478 PMCID: PMC11012216 SCOPUS ID: 2-s2.0-85190379980 04/13/2024       4 Citations
  • Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts. (Yabo YA, Moreno-Sanchez PM, Pires-Afonso Y, Kaoma T, Nosirov B, Scafidi A, Ermini L, Lipsa A, Oudin A, Kyriakis D, Grzyb K, Poovathingal SK, Poli A, Muller A, Toth R, Klink B, Berchem G, Berthold C, Hertel F, Mittelbronn M, Heiland DH, Skupin A, Nazarov PV, Niclou SP, Michelucci A, Golebiewska A) Genome Med 2024 Apr 02;16(1):51 PMID: 38566128 PMCID: PMC10988817 SCOPUS ID: 2-s2.0-85189167658 04/03/2024       22 Citations
  • Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts. (Yabo YA, Moreno-Sanchez PM, Pires-Afonso Y, Kaoma T, Nosirov B, Scafidi A, Ermini L, Lipsa A, Oudin A, Kyriakis D, Grzyb K, Poovathingal SK, Poli A, Muller A, Toth R, Klink B, Berchem G, Berthold C, Hertel F, Mittelbronn M, Heiland DH, Skupin A, Nazarov PV, Niclou SP, Michelucci A, Golebiewska A) bioRxiv 2023 Dec 12 PMID: 36945572 PMCID: PMC10028830 03/23/2023    
  • The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells. (Yang Y, Choppavarapu L, Fang K, Naeini AS, Nosirov B, Li J, Yang K, He Z, Zhou Y, Schiff R, Li R, Hu Y, Wang J, Jin VX) Biochim Biophys Acta Gene Regul Mech 2020 Nov;1863(11):194631 PMID: 32956836 PMCID: PMC7686120 SCOPUS ID: 2-s2.0-85091761490 09/22/2020       13 Citations
  • Reciprocal fine-tuning of progesterone and prolactin-regulated gene expression in breast cancer cells. (Holloran SM, Nosirov B, Walter KR, Trinca GM, Lai Z, Jin VX, Hagan CR) Mol Cell Endocrinol 2020 Jul 01;511:110859 PMID: 32407979 PMCID: PMC8941988 SCOPUS ID: 2-s2.0-85085168333 05/15/2020       6 Citations
  • Mapping circulating serum miRNAs to their immune-related target mRNAs. (Nosirov B, Billaud J, Vandenbon A, Diez D, Wijaya E, Ishii KJ, Teraguchi S, Standley DM) Adv Appl Bioinform Chem 2017;10:1-9 PMID: 28203094 PMCID: PMC5295801 SCOPUS ID: 2-s2.0-85014654909 02/17/2017       4 Citations
    • Last update: 01/08/2026