Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Bin Pan MD

Bin Pan MD profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology
Division: Research

Member of the Neuroscience Research Center

Research Experience

  • Calcium Channels
  • Calcium Signaling
  • Dopamine
  • Mice
  • Monoacylglycerol Lipases
  • Nociceptors
  • Pain
  • Peripheral Nerve Injuries
  • Rats
  • Synapses
  • Synaptic Transmission
  • Thrombospondins
  • Publications (28)

  • Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain. (Wang SM, Goguadze N, Kimura Y, Yasui Y, Pan B, Wang TY, Nakamura Y, Lin YT, Hogan QH, Wilson KL, Su TP, Wu HE) Mol Neurobiol 2021 Jan 18 PMID: 33459966 SCOPUS ID: 2-s2.0-85100181606 01/19/2021    
  • Analgesic dorsal root ganglionic field stimulation blocks conduction of afferent impulse trains selectively in nociceptive sensory afferents. (Chao D, Zhang Z, Mecca CM, Hogan QH, Pan B) Pain 2020 12;161(12):2872-2886 PMID: 32658148 PMCID: PMC7669706 SCOPUS ID: 2-s2.0-85096203014 07/14/2020       2 Citations
  • Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain. (Shin SM, Itson-Zoske B, Cai Y, Qiu C, Pan B, Stucky CL, Hogan QH, Yu H) Mol Pain 2020 Jan-Dec;16:1744806920925425 PMID: 32484015 PMCID: PMC7268132 SCOPUS ID: 2-s2.0-85085909943 06/03/2020       2 Citations
  • Dorsal Root Ganglion Stimulation Alleviates Pain-related Behaviors in Rats with Nerve Injury and Osteoarthritis. (Yu G, Segel I, Zhang Z, Hogan QH, Pan B) Anesthesiology 2020 08;133(2):408-425 PMID: 32433276 SCOPUS ID: 2-s2.0-85088176994 05/21/2020       1 Citation
  • AAV-encoded CaV2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain. (Yu H, Shin SM, Xiang H, Chao D, Cai Y, Xu H, Khanna R, Pan B, Hogan QH) Gene Ther 2019 08;26(7-8):308-323 PMID: 31118475 PMCID: PMC6707887 SCOPUS ID: 2-s2.0-85066867179 05/24/2019       8 Citations
  • Dorsal Root Ganglion Field Stimulation Prevents Inflammation and Joint Damage in a Rat Model of Rheumatoid Arthritis. (Pan B, Zhang Z, Chao D, Hogan QH) Neuromodulation 2018 Apr;21(3):247-253 PMID: 28872725 SCOPUS ID: 2-s2.0-85028826557 09/06/2017       9 Citations
  • Increased thrombospondin-4 after nerve injury mediates disruption of intracellular calcium signaling in primary sensory neurons. (Guo Y, Zhang Z, Wu HE, Luo ZD, Hogan QH, Pan B) Neuropharmacology 2017 05 01;117:292-304 PMID: 28232180 PMCID: PMC5414309 SCOPUS ID: 2-s2.0-85013849482 02/25/2017       11 Citations
  • Dorsal Root Ganglionic Field Stimulation Relieves Spontaneous and Induced Neuropathic Pain in Rats. (Pan B, Yu H, Fischer GJ, Kramer JM, Hogan QH) J Pain 2016 12;17(12):1349-1358 PMID: 27687223 SCOPUS ID: 2-s2.0-84997525072 10/01/2016       21 Citations
  • Thrombospondin-4 divergently regulates voltage-gated Ca2+ channel subtypes in sensory neurons after nerve injury. (Pan B, Guo Y, Wu HE, Park J, Trinh VN, Luo ZD, Hogan QH) Pain 2016 09;157(9):2068-2080 PMID: 27168360 PMCID: PMC4988923 SCOPUS ID: 2-s2.0-84984607525 05/12/2016       20 Citations
  • CaMKII Controls Whether Touch Is Painful. (Yu H, Pan B, Weyer A, Wu HE, Meng J, Fischer G, Vilceanu D, Light AR, Stucky C, Rice FL, Hudmon A, Hogan Q) J Neurosci 2015 Oct 21;35(42):14086-102 PMID: 26490852 PMCID: PMC4683679 SCOPUS ID: 2-s2.0-84944929761 10/23/2015       15 Citations
  • Painful nerve injury upregulates thrombospondin-4 expression in dorsal root ganglia. (Pan B, Yu H, Park J, Yu YP, Luo ZD, Hogan QH) J Neurosci Res 2015 Mar;93(3):443-53 PMID: 25327416 PMCID: PMC4293337 SCOPUS ID: 2-s2.0-84920911767 10/21/2014       19 Citations
  • Divergent effects of painful nerve injury on mitochondrial Ca(2+) buffering in axotomized and adjacent sensory neurons. (Hogan QH, Sprick C, Guo Y, Mueller S, Bienengraeber M, Pan B, Wu HE) Brain Res 2014 Nov 17;1589:112-25 PMID: 25251590 PMCID: PMC4254330 SCOPUS ID: 2-s2.0-84910127976 09/25/2014       6 Citations
  • Regulation of voltage-gated Ca(2+) currents by Ca(2+)/calmodulin-dependent protein kinase II in resting sensory neurons. (Kostic S, Pan B, Guo Y, Yu H, Sapunar D, Kwok WM, Hudmon A, Wu HE, Hogan QH) Mol Cell Neurosci 2014 Sep;62:10-8 PMID: 25064143 PMCID: PMC4187344 SCOPUS ID: 2-s2.0-84906053798 07/30/2014       6 Citations
  • Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons. (Pan B, Guo Y, Kwok WM, Hogan Q, Wu HE) J Pharmacol Exp Ther 2014 Aug;350(2):290-300 PMID: 24891452 PMCID: PMC4109486 SCOPUS ID: 2-s2.0-84904994795 06/04/2014       18 Citations
  • Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling. (Zhong P, Wang W, Pan B, Liu X, Zhang Z, Long JZ, Zhang HT, Cravatt BF, Liu QS) Neuropsychopharmacology 2014 Jun;39(7):1763-76 PMID: 24476943 PMCID: PMC4023150 SCOPUS ID: 2-s2.0-84900565127 01/31/2014       79 Citations
  • Sustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion. (Fischer G, Pan B, Vilceanu D, Hogan QH, Yu H) Gene Ther 2014 Jan;21(1):44-51 PMID: 24152582 PMCID: PMC3881029 SCOPUS ID: 2-s2.0-84891747283 10/25/2013       29 Citations
  • Ca²⁺-dependent regulation of Ca²⁺ currents in rat primary afferent neurons: role of CaMKII and the effect of injury. (Tang Q, Bangaru ML, Kostic S, Pan B, Wu HE, Koopmeiners AS, Yu H, Fischer GJ, McCallum JB, Kwok WM, Hudmon A, Hogan QH) J Neurosci 2012 Aug 22;32(34):11737-49 PMID: 22915116 PMCID: PMC3723336 SCOPUS ID: 2-s2.0-84865228570 08/24/2012       23 Citations
  • Painful nerve injury increases plasma membrane Ca2+-ATPase activity in axotomized sensory neurons. (Gemes G, Oyster KD, Pan B, Wu HE, Bangaru ML, Tang Q, Hogan QH) Mol Pain 2012 Jun 19;8:46 PMID: 22713297 PMCID: PMC3481352 SCOPUS ID: 2-s2.0-84862288445 06/21/2012       25 Citations
  • Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice. (Pan B, Wang W, Zhong P, Blankman JL, Cravatt BF, Liu QS) J Neurosci 2011 Sep 21;31(38):13420-30 PMID: 21940435 PMCID: PMC3371386 SCOPUS ID: 2-s2.0-80053024234 09/24/2011       106 Citations
  • Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. (Zhong P, Pan B, Gao XP, Blankman JL, Cravatt BF, Liu QS) J Physiol 2011 Oct 15;589(Pt 20):4847-55 PMID: 21911610 PMCID: PMC3224879 SCOPUS ID: 2-s2.0-80054113152 09/14/2011       46 Citations
  • Extracellular signal-regulated kinase signaling in the ventral tegmental area mediates cocaine-induced synaptic plasticity and rewarding effects. (Pan B, Zhong P, Sun D, Liu QS) J Neurosci 2011 Aug 03;31(31):11244-55 PMID: 21813685 PMCID: PMC3153072 SCOPUS ID: 2-s2.0-79961216486 08/05/2011       46 Citations
  • Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. (Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ) J Neurosci 2011 Jul 20;31(29):10506-15 PMID: 21775596 PMCID: PMC3179266 SCOPUS ID: 2-s2.0-79960676744 07/22/2011       218 Citations
  • Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. (Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, Cravatt BF) Nat Neurosci 2010 Sep;13(9):1113-9 PMID: 20729846 PMCID: PMC2928870 SCOPUS ID: 2-s2.0-77956181836 08/24/2010       402 Citations
  • Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress. (Wang W, Sun D, Pan B, Roberts CJ, Sun X, Hillard CJ, Liu QS) Neuropsychopharmacology 2010 Oct;35(11):2249-61 PMID: 20664582 PMCID: PMC3055309 SCOPUS ID: 2-s2.0-78651314453 07/29/2010       77 Citations
  • Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling. (Pan B, Wang W, Long JZ, Sun D, Hillard CJ, Cravatt BF, Liu QS) J Pharmacol Exp Ther 2009 Nov;331(2):591-7 PMID: 19666749 PMCID: PMC2775254 SCOPUS ID: 2-s2.0-70350455918 08/12/2009       120 Citations
  • A general model of synaptic transmission and short-term plasticity. (Pan B, Zucker RS) Neuron 2009 May 28;62(4):539-54 PMID: 19477155 PMCID: PMC3035647 SCOPUS ID: 2-s2.0-65649117725 05/30/2009       115 Citations
  • D2 dopamine receptor activation facilitates endocannabinoid-mediated long-term synaptic depression of GABAergic synaptic transmission in midbrain dopamine neurons via cAMP-protein kinase A signaling. (Pan B, Hillard CJ, Liu QS) J Neurosci 2008 Dec 24;28(52):14018-30 PMID: 19109485 PMCID: PMC2656602 SCOPUS ID: 2-s2.0-58149373942 12/26/2008       94 Citations
  • Endocannabinoid signaling mediates cocaine-induced inhibitory synaptic plasticity in midbrain dopamine neurons. (Pan B, Hillard CJ, Liu QS) J Neurosci 2008 Feb 06;28(6):1385-97 PMID: 18256258 PMCID: PMC6671588 SCOPUS ID: 2-s2.0-38949143318 02/08/2008       112 Citations
  • Last update: 03/31/2021