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Medical College of Wisconsin

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David C. Warltier PhD

Emeritus Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology

Member of the Cardiovascular Research Center

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Publications (351)

Cardiomyocyte GTP Cyclohydrolase 1 Protects the Heart Against Diabetic Cardiomyopathy. (Wu HE, Baumgardt SL, Fang J, Paterson M, Liu Y, Du J, Shi Y, Qiao S, Bosnjak ZJ, Warltier DC, Kersten JR, Ge ZD) Sci Rep 2016 Jun 13;6:27925 PMID: 27295516 PMCID: PMC4904741 SCOPUS ID: 2-s2.0-84974802688 06/15/2016 25 Citations

Chronic Co-Administration of Sepiapterin and L-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice. (Baumgardt SL, Paterson M, Leucker TM, Fang J, Zhang DX, Bosnjak ZJ, Warltier DC, Kersten JR, Ge ZD) Circ Heart Fail 2016 Jan;9(1):e002424 PMID: 26763290 PMCID: PMC4714787 SCOPUS ID: 2-s2.0-84955258675 01/15/2016 56 Citations

MicroRNA-21 Mediates Isoflurane-induced Cardioprotection against Ischemia-Reperfusion Injury via Akt/Nitric Oxide Synthase/Mitochondrial Permeability Transition Pore Pathway. (Qiao S, Olson JM, Paterson M, Yan Y, Zaja I, Liu Y, Riess ML, Kersten JR, Liang M, Warltier DC, Bosnjak ZJ, Ge ZD) Anesthesiology 2015 Oct;123(4):786-798 PMID: 26259139 PMCID: PMC4573345 SCOPUS ID: 2-s2.0-84942056683 08/11/2015 70 Citations

Isoflurane favorably modulates guanosine triphosphate cyclohydrolase-1 and endothelial nitric oxide synthase during myocardial ischemia and reperfusion injury in rats. (Baotic I, Weihrauch D, Procknow J, Vasquez-Vivar J, Ge ZD, Sudhakaran S, Warltier DC, Kersten JR) Anesthesiology 2015 Sep;123(3):582-9 PMID: 26192027 PMCID: PMC4543441 SCOPUS ID: 2-s2.0-84964697044 07/21/2015 11 Citations

Cardioprotection during diabetes: the role of mitochondrial DNA. (Muravyeva M, Baotic I, Bienengraeber M, Lazar J, Bosnjak ZJ, Sedlic F, Warltier DC, Kersten JR) Anesthesiology 2014 Apr;120(4):870-9 PMID: 24346177 PMCID: PMC3975667 SCOPUS ID: 2-s2.0-84901722066 12/19/2013 16 Citations

Impairment of endothelial-myocardial interaction increases the susceptibility of cardiomyocytes to ischemia/reperfusion injury. (Leucker TM, Ge ZD, Procknow J, Liu Y, Shi Y, Bienengraeber M, Warltier DC, Kersten JR) PLoS One 2013;8(7):e70088 PMID: 23894596 PMCID: PMC3718730 SCOPUS ID: 2-s2.0-84880689524 07/31/2013 43 Citations

Far red/near infrared light treatment promotes femoral artery collateralization in the ischemic hindlimb. (Lohr NL, Ninomiya JT, Warltier DC, Weihrauch D) J Mol Cell Cardiol 2013 Sep;62:36-42 PMID: 23702287 PMCID: PMC3747970 SCOPUS ID: 2-s2.0-84878680394 05/25/2013 20 Citations

Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia. (Baotic I, Ge ZD, Sedlic F, Coon A, Weihrauch D, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2013 Jul 15;305(2):H219-27 PMID: 23666677 PMCID: PMC3726953 SCOPUS ID: 2-s2.0-84880170764 05/15/2013 20 Citations

Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning. (Vladic N, Ge ZD, Leucker T, Brzezinska AK, Du JH, Shi Y, Warltier DC, Pratt PF Jr, Kersten JR) Am J Physiol Heart Circ Physiol 2011 Nov;301(5):H2130-9 PMID: 21908789 PMCID: PMC3213977 SCOPUS ID: 2-s2.0-80355129947 09/13/2011 36 Citations

Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: implications for preconditioning. (Hirata N, Shim YH, Pravdic D, Lohr NL, Pratt PF Jr, Weihrauch D, Kersten JR, Warltier DC, Bosnjak ZJ, Bienengraeber M) Anesthesiology 2011 Sep;115(3):531-40 PMID: 21862887 PMCID: PMC3337729 SCOPUS ID: 2-s2.0-80052165081 08/25/2011 71 Citations

Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. (Leucker TM, Bienengraeber M, Muravyeva M, Baotic I, Weihrauch D, Brzezinska AK, Warltier DC, Kersten JR, Pratt PF Jr) J Mol Cell Cardiol 2011 Nov;51(5):803-11 PMID: 21791217 PMCID: PMC3342532 SCOPUS ID: 2-s2.0-80053236886 07/28/2011 60 Citations

Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia. (Ge ZD, Ionova IA, Vladic N, Pravdic D, Hirata N, Vásquez-Vivar J, Pratt PF Jr, Warltier DC, Pieper GM, Kersten JR) Cardiovasc Res 2011 Jul 15;91(2):340-9 PMID: 21422102 PMCID: PMC3125073 SCOPUS ID: 2-s2.0-79960007388 03/23/2011 25 Citations

History of post-traumatic stress disorder is associated with impaired neuropsychometric performance after coronary artery surgery. (Hudetz JA, Gandhi SD, Iqbal Z, Patterson KM, Byrne AJ, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2010 Dec;24(6):964-8 PMID: 20494591 SCOPUS ID: 2-s2.0-78649528230 05/25/2010 17 Citations

Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion. (Pravdic D, Mio Y, Sedlic F, Pratt PF, Warltier DC, Bosnjak ZJ, Bienengraeber M) Br J Pharmacol 2010 May;160(2):220-32 PMID: 20423337 PMCID: PMC2874845 SCOPUS ID: 2-s2.0-77951674239 04/29/2010 42 Citations

Preoperative dispositional optimism correlates with a reduced incidence of postoperative delirium and recovery of postoperative cognitive function in cardiac surgical patients. (Hudetz JA, Hoffmann RG, Patterson KM, Byrne AJ, Iqbal Z, Gandhi SD, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2010 Aug;24(4):560-7 PMID: 20346702 SCOPUS ID: 2-s2.0-77955712248 03/30/2010 28 Citations

Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin- and heat shock protein 90-mediated mechanisms. (Amour J, Brzezinska AK, Jager Z, Sullivan C, Weihrauch D, Du J, Vladic N, Shi Y, Warltier DC, Pratt PF Jr, Kersten JR) Anesthesiology 2010 Mar;112(3):576-85 PMID: 20124983 PMCID: PMC2888104 02/04/2010

Postoperative delirium is associated with postoperative cognitive dysfunction at one week after cardiac surgery with cardiopulmonary bypass. (Hudetz JA, Patterson KM, Byrne AJ, Pagel PS, Warltier DC) Psychol Rep 2009 Dec;105(3 Pt 1):921-32 PMID: 20099555 SCOPUS ID: 2-s2.0-85047681658 01/27/2010 37 Citations

A history of alcohol dependence increases the incidence and severity of postoperative cognitive dysfunction in cardiac surgical patients. (Hudetz JA, Patterson KM, Byrne AJ, Iqbal Z, Gandhi SD, Warltier DC, Pagel PS) Int J Environ Res Public Health 2009 Nov;6(11):2725-39 PMID: 20049218 PMCID: PMC2800057 SCOPUS ID: 2-s2.0-73449101823 01/06/2010 24 Citations

Isoflurane postconditioning protects against reperfusion injury by preventing mitochondrial permeability transition by an endothelial nitric oxide synthase-dependent mechanism. (Ge ZD, Pravdic D, Bienengraeber M, Pratt PF Jr, Auchampach JA, Gross GJ, Kersten JR, Warltier DC) Anesthesiology 2010 Jan;112(1):73-85 PMID: 19996950 PMCID: PMC4374483 SCOPUS ID: 2-s2.0-74049154710 12/10/2009 78 Citations

Myocardial interstitial fluid inhibits proliferation and cardiomyocyte differentiation in pluripotent embryonic stem cells. (Van Orman JR, Weihrauch D, Warltier DC, Lough J) Am J Physiol Heart Circ Physiol 2009 Oct;297(4):H1369-76 PMID: 19633209 PMCID: PMC2770771 SCOPUS ID: 2-s2.0-70349610458 07/28/2009 1 Citation

Ketamine attenuates post-operative cognitive dysfunction after cardiac surgery. (Hudetz JA, Iqbal Z, Gandhi SD, Patterson KM, Byrne AJ, Hudetz AG, Pagel PS, Warltier DC) Acta Anaesthesiol Scand 2009 Aug;53(7):864-72 PMID: 19422355 SCOPUS ID: 2-s2.0-67651240248 05/09/2009 174 Citations

Enhancement of nitric oxide release from nitrosyl hemoglobin and nitrosyl myoglobin by red/near infrared radiation: potential role in cardioprotection. (Lohr NL, Keszler A, Pratt P, Bienengraber M, Warltier DC, Hogg N) J Mol Cell Cardiol 2009 Aug;47(2):256-63 PMID: 19328206 PMCID: PMC4329292 SCOPUS ID: 2-s2.0-67649265352 03/31/2009 118 Citations

Morphine reduces the threshold of helium preconditioning against myocardial infarction: the role of opioid receptors in rabbits. (Pagel PS, Krolikowski JG, Amour J, Warltier DC, Weihrauch D) J Cardiothorac Vasc Anesth 2009 Oct;23(5):619-24 PMID: 19231239 PMCID: PMC4401574 SCOPUS ID: 2-s2.0-67649596881 02/24/2009 36 Citations

Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypass. (Hudetz JA, Patterson KM, Iqbal Z, Gandhi SD, Byrne AJ, Hudetz AG, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2009 Oct;23(5):651-7 PMID: 19231245 SCOPUS ID: 2-s2.0-67651203271 02/24/2009 244 Citations

Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning. (Amour J, Brzezinska AK, Weihrauch D, Billstrom AR, Zielonka J, Krolikowski JG, Bienengraeber MW, Warltier DC, Pratt PF Jr, Kersten JR) Anesthesiology 2009 Feb;110(2):317-25 PMID: 19194158 PMCID: PMC2730207 SCOPUS ID: 2-s2.0-61549089097 02/06/2009 60 Citations

Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo. (Zhang DX, Mendoza SA, Bubolz AH, Mizuno A, Ge ZD, Li R, Warltier DC, Suzuki M, Gutterman DD) Hypertension 2009 Mar;53(3):532-8 PMID: 19188524 PMCID: PMC2694062 SCOPUS ID: 2-s2.0-61749092039 02/04/2009 180 Citations

Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism. (Zhang R, Mio Y, Pratt PF, Lohr N, Warltier DC, Whelan HT, Zhu D, Jacobs ER, Medhora M, Bienengraeber M) J Mol Cell Cardiol 2009 Jan;46(1):4-14 PMID: 18930064 PMCID: PMC2640422 SCOPUS ID: 2-s2.0-57149112732 10/22/2008 94 Citations

Zeljko J. Bosnjak, Ph.D., recipient of the 2008 Excellence in Research Award. (Warltier DC) Anesthesiology 2008 Sep;109(3):371-3 PMID: 18754138 SCOPUS ID: 2-s2.0-52649180431 08/30/2008 1 Citation

Inhibition of glycogen synthase kinase or the apoptotic protein p53 lowers the threshold of helium cardioprotection in vivo: the role of mitochondrial permeability transition. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) Anesth Analg 2008 Sep;107(3):769-75 PMID: 18713881 PMCID: PMC2569871 SCOPUS ID: 2-s2.0-51449098817 08/21/2008 34 Citations

The mechanism of helium-induced preconditioning: a direct role for nitric oxide in rabbits. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) Anesth Analg 2008 Sep;107(3):762-8 PMID: 18713880 PMCID: PMC2569865 SCOPUS ID: 2-s2.0-51449099643 08/21/2008 35 Citations

Reactive oxygen species and mitochondrial adenosine triphosphate-regulated potassium channels mediate helium-induced preconditioning against myocardial infarction in vivo. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) J Cardiothorac Vasc Anesth 2008 Aug;22(4):554-9 PMID: 18662630 PMCID: PMC2568984 SCOPUS ID: 2-s2.0-47749116015 07/30/2008 33 Citations

Treatment of acute postoperative hypertension in cardiac surgery patients: an efficacy study of clevidipine assessing its postoperative antihypertensive effect in cardiac surgery-2 (ESCAPE-2), a randomized, double-blind, placebo-controlled trial. (Singla N, Warltier DC, Gandhi SD, Lumb PD, Sladen RN, Aronson S, Newman MF, Corwin HL, ESCAPE-2 Study Group) Anesth Analg 2008 Jul;107(1):59-67 PMID: 18635468 SCOPUS ID: 2-s2.0-49849098985 07/19/2008 94 Citations

Simvastatin restores ischemic preconditioning in the presence of hyperglycemia through a nitric oxide-mediated mechanism. (Gu W, Kehl F, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2008 Apr;108(4):634-42 PMID: 18362595 PMCID: PMC4378683 SCOPUS ID: 2-s2.0-41149175404 03/26/2008 28 Citations

Cognitive function in older diabetic subjects with a history of alcohol abuse. (Hudetz JA, Warltier DC) Psychol Rep 2007 Dec;101(3 Pt 2):1125-32 PMID: 18361128 SCOPUS ID: 2-s2.0-39649092969 03/26/2008 10 Citations

Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection. (Jamnicki-Abegg M, Weihrauch D, Chiari PC, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) J Cardiovasc Pharmacol 2007 Dec;50(6):670-6 PMID: 18091584 SCOPUS ID: 2-s2.0-37349060320 12/20/2007 16 Citations

Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo. (Pagel PS, Krolikowski JG, Shim YH, Venkatapuram S, Kersten JR, Weihrauch D, Warltier DC, Pratt PF Jr) Anesth Analg 2007 Sep;105(3):562-9 PMID: 17717207 SCOPUS ID: 2-s2.0-34548134885 08/25/2007 114 Citations

Volume replacement therapy during major orthopedic surgery using Voluven (hydroxyethyl starch 130/0.4) or hetastarch. (Gandhi SD, Weiskopf RB, Jungheinrich C, Koorn R, Miller D, Shangraw RE, Prough DS, Baus D, Bepperling F, Warltier DC) Anesthesiology 2007 Jun;106(6):1120-7 PMID: 17525586 SCOPUS ID: 2-s2.0-34249688236 05/26/2007 95 Citations

Postoperative cognitive dysfunction in older patients with a history of alcohol abuse. (Hudetz JA, Iqbal Z, Gandhi SD, Patterson KM, Hyde TF, Reddy DM, Hudetz AG, Warltier DC) Anesthesiology 2007 Mar;106(3):423-30 PMID: 17325499 SCOPUS ID: 2-s2.0-34247506262 02/28/2007 80 Citations

Isoflurane preconditioning uncouples mitochondria and protects against hypoxia-reoxygenation. (Ljubkovic M, Mio Y, Marinovic J, Stadnicka A, Warltier DC, Bosnjak ZJ, Bienengraeber M) Am J Physiol Cell Physiol 2007 May;292(5):C1583-90 PMID: 17215328 SCOPUS ID: 2-s2.0-34250630083 01/12/2007 75 Citations

Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits. (Venkatapuram S, Wang C, Krolikowski JG, Weihrauch D, Kersten JR, Warltier DC, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Dec;103(6):1400-5 PMID: 17122210 SCOPUS ID: 2-s2.0-33845671313 11/24/2006 34 Citations

Ischemic preconditioning, myocardial stunning and anesthesia. (Toller WG, Kersten JR, Pagel PS, Warltier DC) Curr Opin Anaesthesiol 2000 Feb;13(1):35-40 PMID: 17016277 SCOPUS ID: 2-s2.0-0034059302 10/04/2006 7 Citations

Mechanism of cardiac sarcolemmal adenosine triphosphate-sensitive potassium channel activation by isoflurane in a heterologous expression system. (Bienengraeber M, Warltier DC, Bosnjak ZJ, Stadnicka A) Anesthesiology 2006 Sep;105(3):534-40 PMID: 16931986 SCOPUS ID: 2-s2.0-33748183792 08/26/2006 9 Citations

Nitrous oxide and preconditioning. (Pagel PS, Warltier DC) Anesthesiology 2006 Sep;105(3):630; author reply 631 PMID: 16932006 SCOPUS ID: 2-s2.0-33748183328 08/26/2006

Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in rats. (Wang C, Weihrauch D, Schwabe DA, Bienengraeber M, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):281-8, table of contents PMID: 16861403 SCOPUS ID: 2-s2.0-33745897224 07/25/2006 75 Citations

Gender-specificity of delayed preconditioning by isoflurane in rabbits: potential role of endothelial nitric oxide synthase. (Wang C, Chiari PC, Weihrauch D, Krolikowski JG, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):274-80, table of contents PMID: 16861402 SCOPUS ID: 2-s2.0-33746576289 07/25/2006 37 Citations

Cardioprotection by volatile anesthetics: new applications for old drugs? (Pratt PF Jr, Wang C, Weihrauch D, Bienengraeber MW, Kersten JR, Pagel PS, Warltier DC) Curr Opin Anaesthesiol 2006 Aug;19(4):397-403 PMID: 16829721 SCOPUS ID: 2-s2.0-33745894991 07/11/2006 33 Citations

Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling. (LaDisa JF Jr, Olson LE, Douglas HA, Warltier DC, Kersten JR, Pagel PS) Biomed Eng Online 2006 Jun 16;5:40 PMID: 16780592 PMCID: PMC1550410 SCOPUS ID: 2-s2.0-33747407371 06/20/2006 128 Citations

The influence of B-cell lymphoma 2 protein, an antiapoptotic regulator of mitochondrial permeability transition, on isoflurane-induced and ischemic postconditioning in rabbits. (Wang C, Neff DA, Krolikowski JG, Weihrauch D, Bienengraeber M, Warltier DC, Kersten JR, Pagel PS) Anesth Analg 2006 May;102(5):1355-60 PMID: 16632808 SCOPUS ID: 2-s2.0-33646200334 04/25/2006 53 Citations

Inhibition of glycogen synthase kinase enhances isoflurane-induced protection against myocardial infarction during early reperfusion in vivo. (Pagel PS, Krolikowski JG, Neff DA, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC) Anesth Analg 2006 May;102(5):1348-54 PMID: 16632807 SCOPUS ID: 2-s2.0-33646191502 04/25/2006 59 Citations

Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivo. (Krolikowski JG, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC, Pagel PS) Can J Anaesth 2006 Feb;53(2):174-82 PMID: 16434759 SCOPUS ID: 2-s2.0-33645769307 01/26/2006 82 Citations

Anesthesiology residency programs for physician scientists. (Knight PR, Warltier DC) Anesthesiology 2006 Jan;104(1):1-4 PMID: 16394681 SCOPUS ID: 2-s2.0-33644866492 01/06/2006 33 Citations

Inhibition of mitochondrial permeability transition enhances isoflurane-induced cardioprotection during early reperfusion: the role of mitochondrial KATP channels. (Krolikowski JG, Bienengraeber M, Weihrauch D, Warltier DC, Kersten JR, Pagel PS) Anesth Analg 2005 Dec;101(6):1590-1596 PMID: 16301224 SCOPUS ID: 2-s2.0-28344451998 11/23/2005 106 Citations

Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening. (LaDisa JF Jr, Olson LE, Hettrick DA, Warltier DC, Kersten JR, Pagel PS) Biomed Eng Online 2005 Oct 26;4:59 PMID: 16250918 PMCID: PMC1276824 SCOPUS ID: 2-s2.0-27744458817 10/28/2005 62 Citations

Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression. (Jamnicki-Abegg M, Weihrauch D, Pagel PS, Kersten JR, Bosnjak ZJ, Warltier DC, Bienengraeber MW) Anesthesiology 2005 Nov;103(5):1006-14 PMID: 16249675 SCOPUS ID: 2-s2.0-27644520393 10/27/2005 68 Citations

Vascular endothelial growth factor is required for coronary collateral growth in the rat. (Toyota E, Warltier DC, Brock T, Ritman E, Kolz C, O'Malley P, Rocic P, Focardi M, Chilian WM) Circulation 2005 Oct 04;112(14):2108-13 PMID: 16203926 SCOPUS ID: 2-s2.0-26944480726 10/06/2005 129 Citations

Aggressive control of intraoperative blood glucose concentration: a shifting paradigm? (Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2005 Oct;103(4):677-8 PMID: 16192757 SCOPUS ID: 2-s2.0-26244467869 09/30/2005 20 Citations

Morphine enhances isoflurane-induced postconditioning against myocardial infarction: the role of phosphatidylinositol-3-kinase and opioid receptors in rabbits. (Weihrauch D, Krolikowski JG, Bienengraeber M, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2005 Oct;101(4):942-949 PMID: 16192500 SCOPUS ID: 2-s2.0-25644448815 09/30/2005 96 Citations

Role of endothelial nitric oxide synthase as a trigger and mediator of isoflurane-induced delayed preconditioning in rabbit myocardium. (Chiari PC, Bienengraeber MW, Weihrauch D, Krolikowski JG, Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2005 Jul;103(1):74-83 PMID: 15983459 SCOPUS ID: 2-s2.0-21744444010 06/29/2005 66 Citations

Cardioprotection by volatile anesthetics. (Bienengraeber MW, Weihrauch D, Kersten JR, Pagel PS, Warltier DC) Vascul Pharmacol 2005;42(5-6):243-52 PMID: 15922257 SCOPUS ID: 2-s2.0-19444371408 06/01/2005 60 Citations

Microfocal X-ray computed tomography post-processing operations for optimizing reconstruction volumes of stented arteries during 3D computational fluid dynamics modeling. (Ladisa JF Jr, Olson LE, Ropella KM, Molthen RC, Haworth ST, Kersten JR, Warltier DC, Pagel PS) Comput Methods Programs Biomed 2005 Aug;79(2):121-34 PMID: 15894401 SCOPUS ID: 2-s2.0-22044442018 05/17/2005 3 Citations

Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure. (Xiao B, Jiang MT, Zhao M, Yang D, Sutherland C, Lai FA, Walsh MP, Warltier DC, Cheng H, Chen SR) Circ Res 2005 Apr 29;96(8):847-55 PMID: 15790957 SCOPUS ID: 2-s2.0-20944432898 03/26/2005 179 Citations

Antegrade iliac artery stent implantation for the temporal and spatial examination of stent-induced neointimal hyperplasia and alterations in regional fluid dynamics. (LaDisa JF Jr, Meier HT, Olson LE, Kersten JR, Warltier DC, Pagel PS) J Pharmacol Toxicol Methods 2005;51(2):115-21 PMID: 15767204 SCOPUS ID: 2-s2.0-17644425726 03/16/2005 11 Citations

Alterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries. (LaDisa JF Jr, Olson LE, Molthen RC, Hettrick DA, Pratt PF, Hardel MD, Kersten JR, Warltier DC, Pagel PS) Am J Physiol Heart Circ Physiol 2005 May;288(5):H2465-75 PMID: 15653759 SCOPUS ID: 2-s2.0-18044371469 01/18/2005 173 Citations

Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits. (Chiari PC, Bienengraeber MW, Pagel PS, Krolikowski JG, Kersten JR, Warltier DC) Anesthesiology 2005 Jan;102(1):102-9 PMID: 15618793 SCOPUS ID: 2-s2.0-11444267248 12/25/2004 252 Citations

Haptoglobin expression and activity during coronary collateralization. (Lohr NL, Warltier DC, Chilian WM, Weihrauch D) Am J Physiol Heart Circ Physiol 2005 Mar;288(3):H1389-95 PMID: 15550518 SCOPUS ID: 2-s2.0-13944252905 11/20/2004 26 Citations

Circumferential vascular deformation after stent implantation alters wall shear stress evaluated with time-dependent 3D computational fluid dynamics models. (LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2005 Mar;98(3):947-57 PMID: 15531564 SCOPUS ID: 2-s2.0-14144250735 11/09/2004 110 Citations

Intravenous emulsified halogenated anesthetics produce acute and delayed preconditioning against myocardial infarction in rabbits. (Chiari PC, Pagel PS, Tanaka K, Krolikowski JG, Ludwig LM, Trillo RA Jr, Puri N, Kersten JR, Warltier DC) Anesthesiology 2004 Nov;101(5):1160-6 PMID: 15505452 SCOPUS ID: 2-s2.0-7244228004 10/27/2004 77 Citations

Protein kinase C inhibitors produce mitochondrial flavoprotein oxidation in cardiac myocytes. (Kohro S, Hogan QH, Warltier DC, Bosnjak ZJ) Anesth Analg 2004 Nov;99(5):1316-1322 PMID: 15502023 SCOPUS ID: 2-s2.0-6444236250 10/27/2004 7 Citations

Preconditioning by isoflurane is mediated by reactive oxygen species generated from mitochondrial electron transport chain complex III. (Ludwig LM, Tanaka K, Eells JT, Weihrauch D, Pagel PS, Kersten JR, Warltier DC) Anesth Analg 2004 Nov;99(5):1308-1315 PMID: 15502022 SCOPUS ID: 2-s2.0-6444220801 10/27/2004 62 Citations

Chronic hyperglycemia attenuates coronary collateral development and impairs proliferative properties of myocardial interstitial fluid by production of angiostatin. (Weihrauch D, Lohr NL, Mraovic B, Ludwig LM, Chilian WM, Pagel PS, Warltier DC, Kersten JR) Circulation 2004 May 18;109(19):2343-8 PMID: 15136506 SCOPUS ID: 2-s2.0-2442718997 05/12/2004 75 Citations

Mechanisms of cardioprotection by volatile anesthetics. (Tanaka K, Ludwig LM, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):707-21 PMID: 15108989 SCOPUS ID: 2-s2.0-1442283719 04/28/2004 256 Citations

Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo. (Alcindor D, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2004 Mar;100(3):547-54 PMID: 15108967 SCOPUS ID: 2-s2.0-1442308452 04/28/2004 42 Citations

Protein kinase C translocation and Src protein tyrosine kinase activation mediate isoflurane-induced preconditioning in vivo: potential downstream targets of mitochondrial adenosine triphosphate-sensitive potassium channels and reactive oxygen species. (Ludwig LM, Weihrauch D, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):532-9 PMID: 15108965 SCOPUS ID: 2-s2.0-1442357312 04/28/2004 86 Citations

Isoflurane produces delayed preconditioning against myocardial ischemia and reperfusion injury: role of cyclooxygenase-2. (Tanaka K, Ludwig LM, Krolikowski JG, Alcindor D, Pratt PF, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):525-31 PMID: 15108964 SCOPUS ID: 2-s2.0-1442332839 04/28/2004 106 Citations

Cardiac pharmacological preconditioning with volatile anesthetics: from bench to bedside? (Riess ML, Stowe DF, Warltier DC) Am J Physiol Heart Circ Physiol 2004 May;286(5):H1603-7 PMID: 15072968 SCOPUS ID: 2-s2.0-1942437496 04/10/2004 94 Citations

Cardioprotection by glucose-insulin-potassium: dependence on KATP channel opening and blood glucose concentration before ischemia. (LaDisa JF Jr, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H601-7 PMID: 15044191 SCOPUS ID: 2-s2.0-3242716828 03/27/2004 36 Citations

Mechanisms of myocardial protection produced by chronic ethanol consumption. (Pagel PS, Kersten JR, Warltier DC) Pathophysiology 2004 Apr;10(2):121-9 PMID: 15006418 SCOPUS ID: 2-s2.0-1542300670 03/10/2004 9 Citations

Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery. (LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Audi SH, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2004 Jul;97(1):424-30; discussion 416 PMID: 14766776 SCOPUS ID: 2-s2.0-3042567527 02/10/2004 148 Citations

Influence of isoflurane on left atrial function in dogs with pacing-induced cardiomyopathy: evaluation with pressure-volume relationships. (Kehl F, Ladisa JF Jr, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2003 Dec;17(6):709-14 PMID: 14689410 SCOPUS ID: 2-s2.0-0347360349 12/23/2003 6 Citations

An automated coronary artery occlusion device for stimulating collateral development in vivo. (Rys R, LaDisa JF Jr, Tessmer JP, Gu W, Kersten JR, Warltier DC, Pagel PS) J Pharmacol Toxicol Methods 2002;48(2):111-8 PMID: 14565568 SCOPUS ID: 2-s2.0-0142043898 10/21/2003 5 Citations

Three-dimensional computational fluid dynamics modeling of alterations in coronary wall shear stress produced by stent implantation. (LaDisa JF Jr, Guler I, Olson LE, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Ann Biomed Eng 2003 Sep;31(8):972-80 PMID: 12918912 SCOPUS ID: 2-s2.0-0041381421 08/16/2003 184 Citations

Reactive oxygen species are critical mediators of coronary collateral development in a canine model. (Gu W, Weihrauch D, Tanaka K, Tessmer JP, Pagel PS, Kersten JR, Chilian WM, Warltier DC) Am J Physiol Heart Circ Physiol 2003 Oct;285(4):H1582-9 PMID: 12816750 SCOPUS ID: 2-s2.0-0141676778 06/21/2003 49 Citations

N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia. (Kehl F, Krolikowski JG, Weihrauch D, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2003 Jun;98(6):1384-90 PMID: 12766647 SCOPUS ID: 2-s2.0-0038443952 05/27/2003 29 Citations

Atrial pacing lead location alters the hemodynamic effects of atrial-ventricular delay in dogs with pacing induced cardiomyopathy. (Hettrick DA, Mittelstadt JR, Kehl F, Kress TT, Tessmer JP, Krolikowski JG, Kersten JR, Warltier DC, Pagel PS) Pacing Clin Electrophysiol 2003 Apr;26(4 Pt 1):853-61 PMID: 12715846 SCOPUS ID: 2-s2.0-0037391176 04/29/2003 10 Citations

Adenosine type 1 (A1) receptors mediate protection against myocardial infarction produced by chronic, intermittent ingestion of ethanol in dogs. (Kehl F, Krolikowski JG, LaDisa JF Jr, Kersten JR, Warltier DC, Pagel PS) Int J Cardiol 2003 Apr;88(2-3):175-82 PMID: 12714196 SCOPUS ID: 2-s2.0-0037399116 04/26/2003 6 Citations

Mechanical function of the left atrium: new insights based on analysis of pressure-volume relations and Doppler echocardiography. (Pagel PS, Kehl F, Gare M, Hettrick DA, Kersten JR, Warltier DC) Anesthesiology 2003 Apr;98(4):975-94 PMID: 12657862 SCOPUS ID: 2-s2.0-0037380679 03/27/2003 190 Citations

Mitochondrial adenosine triphosphate-regulated potassium channel opening acts as a trigger for isoflurane-induced preconditioning by generating reactive oxygen species. (Tanaka K, Weihrauch D, Ludwig LM, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2003 Apr;98(4):935-43 PMID: 12657856 SCOPUS ID: 2-s2.0-0344211929 03/27/2003 117 Citations

Expression of VEGF and angiopoietins-1 and -2 during ischemia-induced coronary angiogenesis. (Matsunaga T, Warltier DC, Tessmer J, Weihrauch D, Simons M, Chilian WM) Am J Physiol Heart Circ Physiol 2003 Jul;285(1):H352-8 PMID: 12649074 SCOPUS ID: 2-s2.0-0037662854 03/22/2003 94 Citations

Modifying cardiovascular risk in diabetes mellitus. (Gu W, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2003 Mar;98(3):774-9 PMID: 12606925 SCOPUS ID: 2-s2.0-0037370396 02/28/2003 72 Citations

Morphine enhances pharmacological preconditioning by isoflurane: role of mitochondrial K(ATP) channels and opioid receptors. (Ludwig LM, Patel HH, Gross GJ, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2003 Mar;98(3):705-11 PMID: 12606915 SCOPUS ID: 2-s2.0-0037371807 02/28/2003 114 Citations

Reactive oxygen species modulate coronary wall shear stress and endothelial function during hyperglycemia. (Gross ER, LaDisa JF Jr, Weihrauch D, Olson LE, Kress TT, Hettrick DA, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2003 May;284(5):H1552-9 PMID: 12543642 SCOPUS ID: 2-s2.0-0037405062 01/25/2003 59 Citations

An intramyocardial catheter for repeated in vivo sampling of interstitial fluid. (Tessmer JP, Pagel PS, Weihrauch D, Ludwig LM, Chilian WM, Kersten JR, Warltier DC) J Pharmacol Toxicol Methods 2002;47(2):73-8 PMID: 12459145 SCOPUS ID: 2-s2.0-0036523146 12/03/2002 4 Citations

Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. (Tanaka K, Weihrauch D, Kehl F, Ludwig LM, LaDisa JF Jr, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2002 Dec;97(6):1485-90 PMID: 12459675 SCOPUS ID: 2-s2.0-0036895112 12/03/2002 151 Citations

Protein tyrosine kinase-dependent modulation of isoflurane effects on cardiac sarcolemmal K(ATP) channel. (Stadnicka A, Kwok WM, Warltier DC, Bosnjak ZJ) Anesthesiology 2002 Nov;97(5):1198-208 PMID: 12411806 SCOPUS ID: 2-s2.0-0036841553 11/02/2002 28 Citations

Isoflurane does not produce a second window of preconditioning against myocardial infarction in vivo. (Kehl F, Pagel PS, Krolikowski JG, Gu W, Toller W, Warltier DC, Kersten JR) Anesth Analg 2002 Nov;95(5):1162-8, table of contents PMID: 12401584 SCOPUS ID: 2-s2.0-0036829291 10/29/2002 54 Citations

Stent implantation alters coronary artery hemodynamics and wall shear stress during maximal vasodilation. (LaDisa JF Jr, Hettrick DA, Olson LE, Guler I, Gross ER, Kress TT, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2002 Dec;93(6):1939-46 PMID: 12391052 SCOPUS ID: 2-s2.0-0036893231 10/23/2002 61 Citations

Increases in coronary collateral blood flow produced by sevoflurane are mediated by calcium-activated potassium (BKCa) channels in vivo. (Kehl F, Krolikowski JG, Tessmer JP, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Sep;97(3):725-31 PMID: 12218541 SCOPUS ID: 2-s2.0-0036725422 09/10/2002 15 Citations

Delta opioid agonists and volatile anesthetics facilitate cardioprotection via potentiation of K(ATP) channel opening. (Patel HH, Ludwig LM, Fryer RM, Hsu AK, Warltier DC, Gross GJ) FASEB J 2002 Sep;16(11):1468-70 PMID: 12205051 SCOPUS ID: 2-s2.0-0036717152 09/03/2002 55 Citations

Editorial view: anesthetic preconditioning: serendipity and science. (Warltier DC, Kersten JR, Pagel PS, Gross GJ) Anesthesiology 2002 Jul;97(1):1-3 PMID: 12131096 SCOPUS ID: 2-s2.0-0036307588 07/20/2002 30 Citations

Attitudes of anesthesiologists about addiction and its treatment: a survey of Illinois and Wisconsin members of the American Society of Anesthesiologists. (May JA, Warltier DC, Pagel PS) J Clin Anesth 2002 Jun;14(4):284-9 PMID: 12088813 SCOPUS ID: 2-s2.0-0036096122 06/29/2002 24 Citations

Propofol alters left atrial function evaluated with pressure-volume relations in vivo. (Kehl F, Kress TT, Mraovic B, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2002 Jun;94(6):1421-6, table of contents PMID: 12031999 SCOPUS ID: 2-s2.0-0036262019 05/29/2002 9 Citations

Reactive oxygen species contribute to contractile dysfunction following rapid ventricular pacing in dogs. (Gare M, Mraovic B, Kehl F, Kersten JR, Warltier DC, Pagel PS) Int J Cardiol 2002 May;83(2):125-31 PMID: 12007684 SCOPUS ID: 2-s2.0-0036253101 05/15/2002 11 Citations

Isoflurane-induced preconditioning is attenuated by diabetes. (Tanaka K, Kehl F, Gu W, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2002 Jun;282(6):H2018-23 PMID: 12003806 SCOPUS ID: 2-s2.0-0036086658 05/11/2002 95 Citations

Prologue: nonclassical modalities of myocardial preconditioning. (Gross GJ, Warltier DC) Am J Physiol Heart Circ Physiol 2002 Jun;282(6):H1951-2 PMID: 12003797 SCOPUS ID: 2-s2.0-0036087071 05/11/2002

Angiostatin inhibits coronary angiogenesis during impaired production of nitric oxide. (Matsunaga T, Weihrauch DW, Moniz MC, Tessmer J, Warltier DC, Chilian WM) Circulation 2002 May 07;105(18):2185-91 PMID: 11994253 SCOPUS ID: 2-s2.0-0037035480 05/08/2002 150 Citations

The role of mitochondrial and sarcolemmal K(ATP) channels in canine ethanol-induced preconditioning in vivo. (Pagel PS, Krolikowski JG, Kehl F, Mraovic B, Kersten JR, Warltier DC) Anesth Analg 2002 Apr;94(4):841-8, table of contents PMID: 11916782 SCOPUS ID: 2-s2.0-0036206139 03/28/2002 21 Citations

Is isoflurane-induced preconditioning dose related? (Kehl F, Krolikowski JG, Mraovic B, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Mar;96(3):675-80 PMID: 11873044 SCOPUS ID: 2-s2.0-0036187525 03/02/2002 108 Citations

Hyperglycemia prevents isoflurane-induced preconditioning against myocardial infarction. (Kehl F, Krolikowski JG, Mraovic B, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2002 Jan;96(1):183-8 PMID: 11753019 SCOPUS ID: 2-s2.0-0036138663 12/26/2001 102 Citations

Hyperglycemia reduces coronary collateral blood flow through a nitric oxide-mediated mechanism. (Kersten JR, Toller WG, Tessmer JP, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2001 Nov;281(5):H2097-104 PMID: 11668071 SCOPUS ID: 2-s2.0-0035200038 10/23/2001 88 Citations

Desflurane, sevoflurane, and isoflurane affect left atrial active and passive mechanical properties and impair left atrial-left ventricular coupling in vivo: analysis using pressure-volume relations. (Gare M, Schwabe DA, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2001 Sep;95(3):689-98 PMID: 11575543 SCOPUS ID: 2-s2.0-0034858094 09/29/2001 34 Citations

Conscious sedation with midazolam or propofol does not alter left ventricular diastolic performance in patients with preexisting diastolic dysfunction: a transmitral and tissue Doppler transthoracic echocardiography study. (Gare M, Parail A, Milosavljevic D, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2001 Oct;93(4):865-71 PMID: 11574347 SCOPUS ID: 2-s2.0-0034813593 09/28/2001 31 Citations

The patient recovering from alcohol or drug addiction: special issues for the anesthesiologist. (May JA, White HC, Leonard-White A, Warltier DC, Pagel PS) Anesth Analg 2001 Jun;92(6):1601-8 PMID: 11375854 SCOPUS ID: 2-s2.0-0035007315 05/29/2001 61 Citations

Diabetes and hyperglycemia impair activation of mitochondrial K(ATP) channels. (Kersten JR, Montgomery MW, Ghassemi T, Gross ER, Toller WG, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2001 Apr;280(4):H1744-50 PMID: 11247788 SCOPUS ID: 2-s2.0-0035008779 03/15/2001 127 Citations

Ethanol enhances the functional recovery of stunned myocardium independent of K(ATP) channels in dogs. (Gross ER, Gare M, Toller WG, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2001 Feb;92(2):299-305 PMID: 11159220 SCOPUS ID: 2-s2.0-0035143525 02/13/2001 13 Citations

K(ATP) channels mediate the beneficial effects of chronic ethanol ingestion. (Pagel PS, Toller WG, Gross ER, Gare M, Kersten JR, Warltier DC) Am J Physiol Heart Circ Physiol 2000 Nov;279(5):H2574-9 PMID: 11045996 SCOPUS ID: 2-s2.0-0033672339 10/25/2000 39 Citations

Sarcolemmal and mitochondrial adenosine triphosphate- dependent potassium channels: mechanism of desflurane-induced cardioprotection. (Toller WG, Gross ER, Kersten JR, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 2000 Jun;92(6):1731-9 PMID: 10839925 SCOPUS ID: 2-s2.0-0034047770 06/06/2000 137 Citations

Isoflurane preconditions myocardium against infarction via activation of inhibitory guanine nucleotide binding proteins. (Toller WG, Kersten JR, Gross ER, Pagel PS, Warltier DC) Anesthesiology 2000 May;92(5):1400-7 PMID: 10781287 SCOPUS ID: 2-s2.0-0034101316 04/26/2000 88 Citations

Correlation of esophageal conductance measurements with aortic and left ventricular diameters and stroke volume. (Hettrick DA, Battocletti JH, Pagel PS, Vurek GG, Tessmer JP, Kersten JR, Warltier DC) IEEE Trans Biomed Eng 2000 Apr;47(4):559-64 PMID: 10763303 SCOPUS ID: 2-s2.0-0034029253 04/14/2000 2 Citations

Diabetes abolishes ischemic preconditioning: role of glucose, insulin, and osmolality. (Kersten JR, Toller WG, Gross ER, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2000 Apr;278(4):H1218-24 PMID: 10749717 SCOPUS ID: 2-s2.0-0034058814 04/06/2000 202 Citations

Approaches to the prevention of perioperative myocardial ischemia. (Warltier DC, Pagel PS, Kersten JR) Anesthesiology 2000 Jan;92(1):253-9 PMID: 10638923 SCOPUS ID: 2-s2.0-0033980389 01/19/2000 148 Citations

Ischemia-induced coronary collateral growth is dependent on vascular endothelial growth factor and nitric oxide. (Matsunaga T, Warltier DC, Weihrauch DW, Moniz M, Tessmer J, Chilian WM) Circulation 2000 Dec 19;102(25):3098-103 PMID: 11120701 SCOPUS ID: 2-s2.0-0034687598 01/11/2000 203 Citations

Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels. (Kersten JR, Montgomery MW, Pagel PS, Warltier DC) Anesth Analg 2000 Jan;90(1):5-11 PMID: 10624967 SCOPUS ID: 2-s2.0-0033959417 01/07/2000 247 Citations

Mechanisms of postischemic contractile dysfunction. (Gross GJ, Kersten JR, Warltier DC) Ann Thorac Surg 1999 Nov;68(5):1898-904 PMID: 10585101 SCOPUS ID: 2-s2.0-0032711491 12/10/1999 101 Citations

Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs. (Toller WG, Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesthesiology 1999 Nov;91(5):1437-46 PMID: 10551596 SCOPUS ID: 2-s2.0-0032730076 11/07/1999 159 Citations

Cloning and expression of canine glycoprotein Ibalpha. (Kenny D, Morateck PA, Fahs SA, Warltier DC, Montgomery RR) Thromb Haemost 1999 Oct;82(4):1327-33 PMID: 10544923 SCOPUS ID: 2-s2.0-0032827491 11/02/1999 8 Citations

Multifactorial basis for coronary collateralization: a complex adaptive response to ischemia. (Kersten JR, Pagel PS, Chilian WM, Warltier DC) Cardiovasc Res 1999 Jul;43(1):44-57 PMID: 10536689 SCOPUS ID: 2-s2.0-0033001169 10/28/1999 59 Citations

Isoflurane-enhanced recovery of canine stunned myocardium: role for protein kinase C? (Toller WG, Montgomery MW, Pagel PS, Hettrick DA, Warltier DC, Kersten JR) Anesthesiology 1999 Sep;91(3):713-22 PMID: 10485783 SCOPUS ID: 2-s2.0-0032842470 09/15/1999 73 Citations

Levosimendan enhances cardiac performance after cardiopulmonary bypass: a prospective, randomized placebo-controlled trial. (Nijhawan N, Nicolosi AC, Montgomery MW, Aggarwal A, Pagel PS, Warltier DC) J Cardiovasc Pharmacol 1999 Aug;34(2):219-28 PMID: 10445673 SCOPUS ID: 2-s2.0-0032771929 08/13/1999 147 Citations

Modulation of the adaptive response to myocardial ischemia by coexisting disease. (Kersten JR, Warltier DC) Am J Physiol 1999 Jun;276(6):H2268-70 PMID: 10362711 SCOPUS ID: 2-s2.0-0033038509 06/11/1999

Finite element model determination of correction factors used for measurement of aortic diameter via conductance. (Hettrick DA, Battocletti J, Ackmann J, Warltier DC) Ann Biomed Eng 1999;27(2):151-9 PMID: 10199691 SCOPUS ID: 2-s2.0-0033087282 04/13/1999 6 Citations

Changes in passive but not active mechanical properties predict recovery of function of stunned myocardium. (Schmeling TJ, Hettrick DA, Kersten JR, Pagel PS, Warltier DC) Ann Biomed Eng 1999;27(2):131-40 PMID: 10199689 SCOPUS ID: 2-s2.0-0033090423 04/13/1999 8 Citations

Sevoflurane selectively increases coronary collateral blood flow independent of KATP channels in vivo. (Kersten JR, Schmeling T, Tessmer J, Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1999 Jan;90(1):246-56 PMID: 9915334 SCOPUS ID: 2-s2.0-0032607620 01/23/1999 31 Citations

RSR13, a synthetic allosteric modifier of hemoglobin, enhances recovery of stunned myocardium in dogs. (Pagel PS, Hettrick DA, Montgomery MW, Kersten JR, Warltier DC) Adv Exp Med Biol 1998;454:527-31 PMID: 9889932 SCOPUS ID: 2-s2.0-0032425041 01/16/1999 1 Citation

Ischemia-induced coronary collateral angiogenesis. (Weihrauch D, Tessmer JP, Kersten JR, Pagel PS, Hettrick DA, Chilian WM, Warltier DC) Adv Exp Med Biol 1998;454:281-6 PMID: 9889902 SCOPUS ID: 2-s2.0-0032444787 01/16/1999 2 Citations

Cardiovascular effects of xenon in isoflurane-anesthetized dogs with dilated cardiomyopathy. (Hettrick DA, Pagel PS, Kersten JR, Tessmer JP, Bosnjak ZJ, Georgieff M, Warltier DC) Anesthesiology 1998 Nov;89(5):1166-73 PMID: 9822005 SCOPUS ID: 2-s2.0-0031771646 11/20/1998 80 Citations

Propofol, but not thiopentone or etomidate, enhances isoflurane-induced coronary vasodilatation in dogs. (Pagel PS, Hettrick DA, Kersten JR, Lowe D, Warltier DC) Can J Anaesth 1998 Aug;45(8):809-17 PMID: 9793674 SCOPUS ID: 2-s2.0-0031792740 10/30/1998 7 Citations

Desflurane and isoflurane produce similar alterations in systemic and pulmonary hemodynamics and arterial oxygenation in patients undergoing one-lung ventilation during thoracotomy. (Pagel PS, Fu JL, Damask MC, Davis RF, Samuelson PN, Howie MB, Warltier DC) Anesth Analg 1998 Oct;87(4):800-7 PMID: 9768773 SCOPUS ID: 2-s2.0-0031708057 10/13/1998 66 Citations

Dexmedetomidine produces similar alterations in the determinants of left ventricular afterload in conscious dogs before and after the development of pacing-induced cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Warltier DC) Anesthesiology 1998 Sep;89(3):741-8 PMID: 9743413 SCOPUS ID: 2-s2.0-0031663523 09/22/1998 10 Citations

Interpretation of nonpulsatile arterial pressure-flow relations during cardiopulmonary bypass. (Hettrick DA, Kersten JR, Pagel PS, Warltier DC) Anesth Analg 1998 Sep;87(3):743 PMID: 9728869 SCOPUS ID: 2-s2.0-0031681269 09/05/1998

Repetitive coronary artery occlusions induce release of growth factors into the myocardial interstitium. (Weihrauch D, Tessmer J, Warltier DC, Chilian WM) Am J Physiol 1998 Sep;275(3):H969-76 PMID: 9724302 SCOPUS ID: 2-s2.0-0031678622 09/02/1998 41 Citations

A novel alpha 2-adrenoceptor antagonist attenuates the early, but preserves the late cardiovascular effects of intravenous dexmedetomidine in conscious dogs. (Pagel PS, Proctor LT, Devcic A, Hettrick DA, Kersten JR, Tessmer JP, Farber NE, Schmeling WT, Warltier DC) J Cardiothorac Vasc Anesth 1998 Aug;12(4):429-34 PMID: 9713732 SCOPUS ID: 2-s2.0-0031830347 08/26/1998 55 Citations

Acute hyperglycemia abolishes ischemic preconditioning in vivo. (Kersten JR, Schmeling TJ, Orth KG, Pagel PS, Warltier DC) Am J Physiol 1998 Aug;275(2):H721-5 PMID: 9683464 SCOPUS ID: 2-s2.0-0031823315 07/31/1998 194 Citations

Cardiovascular effects of verapamil enantiomer combinations in conscious dogs. (Pagel PS, Hettrick DA, Lowe D, Gowrie PW, Kersten JR, Bosnjak ZJ, Warltier DC) Eur J Pharmacol 1998 May 08;348(2-3):213-21 PMID: 9652336 SCOPUS ID: 2-s2.0-0032496071 07/04/1998 12 Citations

Etomidate adversely alters determinants of left ventricular afterload in dogs with dilated cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Tessmer JP, Lowe D, Warltier DC) Anesth Analg 1998 May;86(5):932-8 PMID: 9585271 SCOPUS ID: 2-s2.0-0031960885 05/19/1998 19 Citations

RSR13, a synthetic modifier of hemoglobin-oxygen affinity, enhances the recovery of stunned myocardium in anesthetized dogs. (Pagel PS, Hettrick DA, Montgomery MW, Kersten JR, Steffen RP, Warltier DC) J Pharmacol Exp Ther 1998 Apr;285(1):1-8 PMID: 9535987 SCOPUS ID: 2-s2.0-0031968729 05/16/1998 27 Citations

In vivo measurement of real-time aortic segmental volume using the conductance catheter. (Hettrick DA, Battocletti J, Ackmann J, Linehan J, Warltier DC) Ann Biomed Eng 1998;26(3):431-40 PMID: 9570226 SCOPUS ID: 2-s2.0-0032067284 05/07/1998 12 Citations

Differential roles of myocardial Ca2+ channels and Na+/Ca2+ exchange in myocardial reperfusion injury in open chest dogs: relative roles during ischemia and reperfusion. (Smart SC, Sagar KB, Warltier DC) Cardiovasc Res 1997 Dec;36(3):337-46 PMID: 9534854 SCOPUS ID: 2-s2.0-0031455786 04/16/1998 20 Citations

Activation of adenosine triphosphate-regulated potassium channels: mediation of cellular and organ protection. (Kersten JR, Gross GJ, Pagel PS, Warltier DC) Anesthesiology 1998 Feb;88(2):495-513 PMID: 9477071 SCOPUS ID: 2-s2.0-0031915864 02/26/1998 81 Citations

Injury to the Ca2+ ATPase of the sarcoplasmic reticulum in anesthetized dogs contributes to myocardial reperfusion injury. (Smart SC, Sagar KB, el Schultz J, Warltier DC, Jones LR) Cardiovasc Res 1997 Nov;36(2):174-84 PMID: 9463629 SCOPUS ID: 2-s2.0-0031260637 02/17/1998 20 Citations

Cardiovascular effects of propofol in dogs with dilated cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Lowe D, Warltier DC) Anesthesiology 1998 Jan;88(1):180-9 PMID: 9447871 SCOPUS ID: 2-s2.0-0031982992 02/03/1998 34 Citations

Beta-adrenergic-blocking drugs: incredibly useful, incredibly underutilized. (Warltier DC) Anesthesiology 1998 Jan;88(1):2-5 PMID: 9447848 SCOPUS ID: 2-s2.0-0031605345 02/03/1998 51 Citations

Isoflurane and halothane do not alter the enhanced afterload sensitivity of left ventricular relaxation in dogs with pacing-induced cardiomyopathy. (Pagel PS, Hettrick DA, Kersten JR, Tessmer JP, Lowe D, Warltier DC) Anesthesiology 1997 Oct;87(4):952-62 PMID: 9357899 SCOPUS ID: 2-s2.0-0030723418 11/14/1997 10 Citations

The effects of isoflurane and halothane on left ventricular afterload in dogs with dilated cardiomyopathy. (Hettrick DA, Pagel PS, Kersten JR, Lowe D, Warltier DC) Anesth Analg 1997 Nov;85(5):979-86 PMID: 9356087 SCOPUS ID: 2-s2.0-0030777936 11/14/1997 17 Citations

Hemodynamic effects of repetitive cocaine administration. (Pagel PS, Warltier DC) Circulation 1997 Aug 05;96(3):1050 PMID: 9264524 SCOPUS ID: 2-s2.0-0030743592 08/05/1997

Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: reduction of myocardial infarct size with an acute memory phase. (Kersten JR, Schmeling TJ, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 1997 Aug;87(2):361-70 PMID: 9286901 SCOPUS ID: 2-s2.0-0030866804 08/01/1997 465 Citations

The leukocyte cell adhesion cascade and its role in myocardial ischemia-reperfusion injury. (Gumina RJ, Newman PJ, Kenny D, Warltier DC, Gross GJ) Basic Res Cardiol 1997 Aug;92(4):201-13 PMID: 9342427 SCOPUS ID: 2-s2.0-0030763034 08/01/1997 33 Citations

Intracoronary levosimendan enhances contractile function of stunned myocardium. (Jamali IN, Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesth Analg 1997 Jul;85(1):23-9 PMID: 9212117 SCOPUS ID: 2-s2.0-0030857836 07/01/1997 108 Citations

Positive inotropic and lusitropic effects of triiodothyronine in conscious dogs with pacing-induced cardiomyopathy. (Jamall IN, Pagel PS, Hettrick DA, Lowe D, Kersten JR, Tessmer JP, Warltier DC) Anesthesiology 1997 Jul;87(1):102-9 PMID: 9232140 SCOPUS ID: 2-s2.0-0030763343 07/01/1997 7 Citations

Role of adenosine in isoflurane-induced cardioprotection. (Kersten JR, Orth KG, Pagel PS, Mei DA, Gross GJ, Warltier DC) Anesthesiology 1997 May;86(5):1128-39 PMID: 9158363 SCOPUS ID: 2-s2.0-0031005282 05/01/1997 103 Citations

Alterations in canine left ventricular-arterial coupling and mechanical efficiency produced by propofol. (Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1997 May;86(5):1088-93 PMID: 9158358 SCOPUS ID: 2-s2.0-0030939331 05/01/1997 28 Citations

Temporal dependence of coronary collateral development. (Kersten JR, McGough MF, Pagel PS, Tessmer JP, Warltier DC) Cardiovasc Res 1997 May;34(2):306-12 PMID: 9205544 SCOPUS ID: 2-s2.0-0031005004 05/01/1997 20 Citations

Levosimendan enhances left ventricular systolic and diastolic function in conscious dogs with pacing-induced cardiomyopathy. (Pagel PS, McGough MF, Hettrick DA, Lowe D, Tessmer JP, Jamali IN, Warltier DC) J Cardiovasc Pharmacol 1997 May;29(5):563-73 PMID: 9213196 SCOPUS ID: 2-s2.0-0030918670 05/01/1997 55 Citations

Effects of isoflurane and propofol on arterial mechanical properties. (Hettrick DA, Pagel PS, Warltier DC) Anesth Analg 1997 Apr;84(4):940-1 PMID: 9085995 SCOPUS ID: 2-s2.0-0030934683 04/01/1997 2 Citations

Effects of levosimendan on left ventricular function: correlation with plasma concentrations in conscious dogs. (McGough MF, Pagel PS, Lowe D, Hettrick DA, Kersten JR, Warltier DC) J Cardiothorac Vasc Anesth 1997 Feb;11(1):49-53 PMID: 9058220 SCOPUS ID: 2-s2.0-0031048221 02/01/1997 16 Citations

Effects of physical parameters on the cylindrical model for volume measurement by conductance. (Hettrick DA, Battocletti JH, Ackmann JJ, Linehan JH, Warltier DC) Ann Biomed Eng 1997;25(1):126-34 PMID: 9124727 SCOPUS ID: 2-s2.0-0031029416 01/01/1997 14 Citations

Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury. (Gumina RJ, el Schultz J, Yao Z, Kenny D, Warltier DC, Newman PJ, Gross GJ) Circulation 1996 Dec 15;94(12):3327-33 PMID: 8989147 12/15/1996

Increases in inotropic state without change in heart rate: combined use of dobutamine and zatebradine in conscious dogs. (Hettrick DA, Pagel PS, Lowe D, Tessmer JP, Warltier DC) Eur J Pharmacol 1996 Dec 05;316(2-3):237-44 PMID: 8982692 SCOPUS ID: 2-s2.0-0030571517 12/05/1996 9 Citations

Isoflurane and halothane produce similar alterations in aortic distensibility and characteristic aortic impedance. (Hettrick DA, Pagel PS, Warltier DC) Anesth Analg 1996 Dec;83(6):1166-72 PMID: 8942580 SCOPUS ID: 2-s2.0-0029988241 12/01/1996 15 Citations

In vitro and finite-element model investigation of the conductance technique for measurement of aortic segmental volume. (Hettrick DA, Battocletti JH, Ackmann JJ, Linehan JH, Warltier DC) Ann Biomed Eng 1996;24(6):675-84 PMID: 8923987 SCOPUS ID: 2-s2.0-0030296870 11/01/1996 13 Citations

Influence of levosimendan, pimobendan, and milrinone on the regional distribution of cardiac output in anaesthetized dogs. (Pagel PS, Hettrick DA, Warltier DC) Br J Pharmacol 1996 Oct;119(3):609-15 PMID: 8894186 PMCID: PMC1915696 SCOPUS ID: 2-s2.0-0029788449 10/01/1996 117 Citations

Mechanism of myocardial protection by isoflurane. Role of adenosine triphosphate-regulated potassium (KATP) channels. (Kersten JR, Schmeling TJ, Hettrick DA, Pagel PS, Gross GJ, Warltier DC) Anesthesiology 1996 Oct;85(4):794-807; discussion 27A PMID: 8873550 SCOPUS ID: 2-s2.0-0029909986 10/01/1996 172 Citations

Isoflurane, but not halothane, improves indices of diastolic performance in dogs with rapid ventricular, pacing-induced cardiomyopathy. (Pagel PS, Lowe D, Hettrick DA, Jamali IN, Kersten JR, Tessmer JP, Warltier DC) Anesthesiology 1996 Sep;85(3):644-54 PMID: 8853096 SCOPUS ID: 2-s2.0-0029743734 09/01/1996 21 Citations

Desflurane, sevoflurane, and isoflurane impair canine left ventricular-arterial coupling and mechanical efficiency. (Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1996 Aug;85(2):403-13 PMID: 8712457 SCOPUS ID: 2-s2.0-0029841955 08/01/1996 58 Citations

Glyburide, a KATP channel antagonist, attenuates the cardioprotective effects of isoflurane in stunned myocardium. (Kersten JR, Lowe D, Hettrick DA, Pagel PS, Gross GJ, Warltier DC) Anesth Analg 1996 Jul;83(1):27-33 PMID: 8659760 SCOPUS ID: 2-s2.0-0029665795 07/01/1996 87 Citations

Influence of volatile anesthetics on left ventricular afterload in vivo. Differences between desflurane and sevoflurane. (Lowe D, Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1996 Jul;85(1):112-20 PMID: 8694356 SCOPUS ID: 2-s2.0-0030054610 07/01/1996 43 Citations

Levosimendan potentiates the inotropic actions of dopamine in conscious dogs. (McGough MF, Pagel PS, Lowe D, Hettrick DA, Warltier DC) J Cardiovasc Pharmacol 1996 Jul;28(1):36-47 PMID: 8797134 SCOPUS ID: 2-s2.0-0029973074 07/01/1996 12 Citations

Comparison of the effects of levosimendan, pimobendan, and milrinone on canine left ventricular-arterial coupling and mechanical efficiency. (Pagel PS, Hettrick DA, Warltier DC) Basic Res Cardiol 1996;91(4):296-307 PMID: 8874779 SCOPUS ID: 2-s2.0-0029776380 07/01/1996 39 Citations

Comparison of the cardiovascular effects of two novel superoxide dismutase mimetics, SC-55858 and SC-54417, in conscious dogs. (Lowe D, Pagel PS, McGough MF, Hettrick DA, Warltier DC) Eur J Pharmacol 1996 May 23;304(1-3):81-6 PMID: 8813587 SCOPUS ID: 2-s2.0-0030598627 05/23/1996 10 Citations

Assessment of right ventricular function in swine using sonomicrometry and conductance. (Nicolosi AC, Hettrick DA, Warltier DC) Ann Thorac Surg 1996 May;61(5):1381-7; discussion 1387-8 PMID: 8633946 SCOPUS ID: 2-s2.0-0029933402 05/01/1996 14 Citations

Propofol alters left ventricular afterload as evaluated by aortic input impedance in dogs. (Lowe D, Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1996 Feb;84(2):368-76 PMID: 8602668 SCOPUS ID: 2-s2.0-0030059022 02/01/1996 39 Citations

Differential hemodynamic effects of the nitric oxide donor pirsidomine in comparison to SIN-1, nitroprusside and nitroglycerin. (Arkonac BM, Kersten JR, Wynsen JC, Nijhawan N, Warltier DC) Pharmacology 1996 Feb;52(2):92-100 PMID: 8851630 SCOPUS ID: 2-s2.0-0030066413 02/01/1996 4 Citations

Desflurane and isoflurane exert modest beneficial actions on left ventricular diastolic function during myocardial ischemia in dogs. (Pagel PS, Hettrick DA, Lowe D, Tessmer JP, Warltier DC) Anesthesiology 1995 Nov;83(5):1021-35 PMID: 7486153 SCOPUS ID: 2-s2.0-0028879874 11/01/1995 36 Citations

Intracoronary amiloride prevents contractile dysfunction of postischemic "stunned" myocardium: role of hemodynamic alterations and inhibition of Na+/H+ exchange and L-type Ca2+ channels. (Smart SC, LoCurto A, el Schultz J, Sagar KB, Warltier DC) J Am Coll Cardiol 1995 Nov 01;26(5):1365-73 PMID: 7594055 SCOPUS ID: 2-s2.0-0028863116 11/01/1995 13 Citations

Zatebradine, a specific bradycardic agent, alters the hemodynamic and left ventricular mechanical actions of levosimendan, a new myofilament calcium sensitizer, in conscious dogs. (Pagel PS, Harkin CP, Hettrick DA, Warltier DC) J Pharmacol Exp Ther 1995 Oct;275(1):127-35 PMID: 7562540 SCOPUS ID: 2-s2.0-0028826965 10/01/1995 18 Citations

Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs. (Harkin CP, Pagel PS, Tessmer JP, Warltier DC) J Cardiovasc Pharmacol 1995 Aug;26(2):179-88 PMID: 7475041 SCOPUS ID: 2-s2.0-0029097331 08/01/1995 61 Citations

Differential effects of isoflurane and halothane on aortic input impedance quantified using a three-element Windkessel model. (Hettrick DA, Pagel PS, Warltier DC) Anesthesiology 1995 Aug;83(2):361-73 PMID: 7631959 SCOPUS ID: 2-s2.0-0029125309 08/01/1995 32 Citations

Modulation of coronary collateral angiogenesis: a canine model of neovascularization induced by chronic ischemia. (Kersten JR, Warltier DC) J Card Surg 1995 Jul;10(4 Pt 1):354-7 PMID: 7549194 SCOPUS ID: 2-s2.0-0029088550 07/01/1995 5 Citations

Protamine inhibits coronary collateral development in a canine model of repetitive coronary occlusion. (Kersten JR, Pagel PS, Warltier DC) Am J Physiol 1995 Feb;268(2 Pt 2):H720-8 PMID: 7532374 SCOPUS ID: 2-s2.0-0028945183 02/01/1995 19 Citations

Dexmedetomidine partially attenuates the sympathetically mediated systemic and coronary hemodynamic effects of cocaine. (Kersten JR, Pagel PS, Hettrick DA, Warltier DC) Anesth Analg 1995 Jan;80(1):114-21 PMID: 7802267 SCOPUS ID: 2-s2.0-0028797967 01/01/1995 17 Citations

Relation of ultrasonic backscatter and acoustic propagation properties to myofibrillar length and myocardial thickness. (O'Brien PD, O'Brien WD Jr, Rhyne TL, Warltier DC, Sagar KB) Circulation 1995 Jan 01;91(1):171-5 PMID: 7805199 SCOPUS ID: 2-s2.0-0028854877 01/01/1995 68 Citations

Acoustic propagation properties of normal, stunned, and infarcted myocardium. Morphological and biochemical determinants. (O'Brien WD, Sagar KB, Warltier DC, Rhyne TL) Circulation 1995 Jan 01;91(1):154-60 PMID: 7805196 SCOPUS ID: 2-s2.0-0028850825 01/01/1995 42 Citations

Cultured endothelial cells restore vasodilator responses to coronary arteries with impaired endothelial function and alter the response to a nitric oxide donor. (Kenny D, Coughlan MG, Kampine JP, Montgomery RR, Bosnjak ZJ, Warltier DC) Pharmacology 1994 Oct;49(4):249-56 PMID: 7831388 SCOPUS ID: 2-s2.0-0028050348 10/01/1994 3 Citations

Perfusion of ischemic myocardium during anesthesia with sevoflurane. (Kersten JR, Brayer AP, Pagel PS, Tessmer JP, Warltier DC) Anesthesiology 1994 Oct;81(4):995-1004 PMID: 7943851 SCOPUS ID: 2-s2.0-0027959674 10/01/1994 63 Citations

Levosimendan (OR-1259), a myofilament calcium sensitizer, enhances myocardial contractility but does not alter isovolumic relaxation in conscious and anesthetized dogs. (Pagel PS, Harkin CP, Hettrick DA, Warltier DC) Anesthesiology 1994 Oct;81(4):974-87 PMID: 7943849 SCOPUS ID: 2-s2.0-0027942068 10/01/1994 73 Citations

Systemic and coronary hemodynamic effects of repetitive cocaine administration in conscious dogs. (Pagel PS, Tessmer JP, Warltier DC) J Cardiovasc Pharmacol 1994 Sep;24(3):443-53 PMID: 7528301 SCOPUS ID: 2-s2.0-0028147263 09/01/1994 14 Citations

Oral dexmedetomidine preserves baroreceptor function and decreases anesthetic requirements of halothane-anesthetized dogs. (Devcic A, Schmeling WT, Kampine JP, Warltier DC) Anesthesiology 1994 Aug;81(2):419-30 PMID: 8053593 SCOPUS ID: 2-s2.0-0028116955 08/01/1994 25 Citations

Direct negative inotropic and lusitropic effects of sevoflurane. (Harkin CP, Pagel PS, Kersten JR, Hettrick DA, Warltier DC) Anesthesiology 1994 Jul;81(1):156-67 PMID: 8042785 SCOPUS ID: 2-s2.0-0028275793 07/01/1994 95 Citations

Left ventricular mechanical consequences of dihydropyridine calcium channel modulation in conscious and anesthetized chronically instrumented dogs. (Pagel PS, Hettrick DA, Warltier DC) Anesthesiology 1994 Jul;81(1):190-208 PMID: 7519000 SCOPUS ID: 2-s2.0-0028301120 07/01/1994 11 Citations

Transforming growth factor beta 1 preserves endothelial function after multiple brief coronary artery occlusions and reperfusion. (Kenny D, Coughlan MG, Pagel PS, Kampine JP, Warltier DC) Am Heart J 1994 Jun;127(6):1456-61 PMID: 8197968 SCOPUS ID: 2-s2.0-0028244164 06/01/1994 28 Citations

Volatile anesthetics and coronary collateral circulation. (Kersten JR, Hartman JC, Pagel PS, Warltier DC) Adv Pharmacol 1994;31:269-84 PMID: 7873418 SCOPUS ID: 2-s2.0-0028725468 01/01/1994 1 Citation

Zatebradine, a specific bradycardic agent, enhances the positive inotropic actions of dobutamine in ischemic myocardium. (Wynsen JC, O'Brien PD, Warltier DC) J Am Coll Cardiol 1994 Jan;23(1):233-41 PMID: 8277087 SCOPUS ID: 2-s2.0-0027957433 01/01/1994 14 Citations

Mechanical consequences of calcium channel modulation during volatile anesthetic-induced left ventricular systolic and diastolic dysfunction. (Pagel PS, Warltier DC) Adv Pharmacol 1994;31:125-43 PMID: 7532986 SCOPUS ID: 2-s2.0-0028719479 01/01/1994 1 Citation

Quantitation of volatile anesthetic-induced depression of myocardial contractility using a single beat index derived from maximal ventricular power. (Pagel PS, Nijhawan N, Warltier DC) J Cardiothorac Vasc Anesth 1993 Dec;7(6):688-95 PMID: 8305659 SCOPUS ID: 2-s2.0-0027131623 12/01/1993 15 Citations

Intraoperative bronchospasm caused by adenosine. (Aggarwal A, Farber NE, Warltier DC) Anesthesiology 1993 Nov;79(5):1132-5 PMID: 8238991 SCOPUS ID: 2-s2.0-0027442023 11/01/1993 16 Citations

Dexmedetomidine alters the hemodynamic effects of desflurane and isoflurane in chronically instrumented dogs. (Kersten J, Pagel PS, Tessmer JP, Roerig DL, Schmeling WT, Warltier DC) Anesthesiology 1993 Nov;79(5):1022-32 PMID: 7902030 SCOPUS ID: 2-s2.0-0027370292 11/01/1993 23 Citations

Left ventricular diastolic function in the normal and diseased heart. Perspectives for the anesthesiologist (2). (Pagel PS, Grossman W, Haering JM, Warltier DC) Anesthesiology 1993 Nov;79(5):1104-20 PMID: 8238987 SCOPUS ID: 2-s2.0-0027519550 11/01/1993 41 Citations

Amrinone enhances myocardial contractility and improves left ventricular diastolic function in conscious and anesthetized chronically instrumented dogs. (Pagel PS, Hettrick DA, Warltier DC) Anesthesiology 1993 Oct;79(4):753-65 PMID: 8214755 SCOPUS ID: 2-s2.0-0027517921 10/01/1993 22 Citations

Left ventricular diastolic function in the normal and diseased heart. Perspectives for the anesthesiologist (1). (Pagel PS, Grossman W, Haering JM, Warltier DC) Anesthesiology 1993 Oct;79(4):836-54 PMID: 8214764 SCOPUS ID: 2-s2.0-0027435612 10/01/1993 61 Citations

Differential sensitivity of proximal and distal coronary arteries to a nitric oxide donor following reperfusion injury or inhibition of nitric oxide synthesis. (Coughlan MG, Kenny D, Kampine JP, Bosnjak ZJ, Warltier DC) Cardiovasc Res 1993 Aug;27(8):1444-8 PMID: 8221797 SCOPUS ID: 2-s2.0-85047679570 08/01/1993 12 Citations

Recovery of contractile function of postischemic, reperfused myocardium: influence of 2,3-butanedione-2-monoxime. (O'Brien P, Bosnjak Z, Warltier DC) J Cardiovasc Pharmacol 1993 May;21(5):693-700 PMID: 7685437 SCOPUS ID: 2-s2.0-0027506379 05/01/1993 8 Citations

Relationship of severity of myocardial stunning to ATP dependent potassium channel modulation. (Warltier DC, Auchampach JA, Gross GJ) J Card Surg 1993 Mar;8(2 Suppl):279-83 PMID: 8461517 SCOPUS ID: 2-s2.0-0027523308 03/01/1993 12 Citations

Evaluation of myocardial contractility in the chronically instrumented dog with intact autonomic nervous system function: effects of desflurane and isoflurane. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Acta Anaesthesiol Scand 1993 Feb;37(2):203-10 PMID: 8447212 SCOPUS ID: 2-s2.0-0027471990 02/01/1993 29 Citations

Reversal of volatile anesthetic-induced depression of myocardial contractility by extracellular calcium also enhances left ventricular diastolic function. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1993 Jan;78(1):141-54 PMID: 8424547 SCOPUS ID: 2-s2.0-0027388902 01/01/1993 45 Citations

Negative inotropic effects of propofol as evaluated by the regional preload recruitable stroke work relationship in chronically instrumented dogs. (Pagel PS, Warltier DC) Anesthesiology 1993 Jan;78(1):100-8 PMID: 8424542 SCOPUS ID: 2-s2.0-0027399919 01/01/1993 133 Citations

Myocardial and endothelial dysfunction after multiple, brief coronary occlusions: role of oxygen radicals. (Gross GJ, O'Rourke ST, Pelc LR, Warltier DC) Am J Physiol 1992 Dec;263(6 Pt 2):H1703-9 PMID: 1481896 SCOPUS ID: 2-s2.0-0027054538 12/01/1992 68 Citations

Effect of omega-3 fatty acids on the vascular response to angiotensin in normotensive men. (Kenny D, Warltier DC, Pleuss JA, Hoffmann RG, Goodfriend TL, Egan BM) Am J Cardiol 1992 Nov 15;70(15):1347-52 PMID: 1442589 SCOPUS ID: 2-s2.0-0026472092 11/15/1992 79 Citations

Direct coronary and cerebral vascular responses to dexmedetomidine. Significance of endogenous nitric oxide synthesis. (Coughlan MG, Lee JG, Bosnjak ZJ, Schmeling WT, Kampine JP, Warltier DC) Anesthesiology 1992 Nov;77(5):998-1006 PMID: 1359812 SCOPUS ID: 2-s2.0-0026440614 11/01/1992 62 Citations

Nitrous oxide impairs functional recovery of stunned myocardium in barbiturate-anesthetized, acutely instrumented dogs. (Siker D, Pagel PS, Pelc LR, Kampine JP, Schmeling WT, Warltier DC) Anesth Analg 1992 Oct;75(4):539-48 PMID: 1530167 SCOPUS ID: 2-s2.0-0026709089 10/01/1992 17 Citations

Influence of desflurane, isoflurane and halothane on regional tissue perfusion in dogs. (Hartman JC, Pagel PS, Proctor LT, Kampine JP, Schmeling WT, Warltier DC) Can J Anaesth 1992 Oct;39(8):877-87 PMID: 1288912 SCOPUS ID: 2-s2.0-0026539684 10/01/1992 91 Citations

ASA Award: John P. Kampine. (Warltier DC) Anesthesiology 1992 Oct;77(4):623-5 PMID: 1416158 SCOPUS ID: 2-s2.0-0026938952 10/01/1992

Cardiovascular and respiratory actions of desflurane: is desflurane different from isoflurane? (Warltier DC, Pagel PS) Anesth Analg 1992 Oct;75(4 Suppl):S17-29; discussion S29-31 PMID: 1524236 SCOPUS ID: 2-s2.0-0026783903 10/01/1992 75 Citations

Premedication with oral dexmedetomidine alters hemodynamic actions of intravenous anesthetic agents in chronically instrumented dogs. (Proctor LT, Schmeling WT, Warltier DC) Anesthesiology 1992 Sep;77(3):554-62 PMID: 1355639 SCOPUS ID: 2-s2.0-0026785496 09/01/1992 11 Citations

Attenuation of the systemic and coronary hemodynamic effects of cocaine in conscious dogs: propranolol versus labetalol. (Kenny D, Pagel PS, Warltier DC) Basic Res Cardiol 1992;87(5):465-77 PMID: 1334401 SCOPUS ID: 2-s2.0-0026445946 09/01/1992 27 Citations

Cocaine depresses myocardial contractility and prolongs isovolumetric relaxation in conscious dogs with partial autonomic nervous system blockade. (Pagel PS, Power MW, Kenny D, Warltier DC) J Cardiovasc Pharmacol 1992 Jul;20(1):25-34 PMID: 1383628 SCOPUS ID: 2-s2.0-0026723424 07/01/1992 10 Citations

Ketamine depresses myocardial contractility as evaluated by the preload recruitable stroke work relationship in chronically instrumented dogs with autonomic nervous system blockade. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1992 Apr;76(4):564-72 PMID: 1550282 SCOPUS ID: 2-s2.0-0026582747 04/01/1992 67 Citations

Regional redistribution of myocardial perfusion by UL-FS 49, a selective bradycardic agent. (O'Brien P, Drage D, Saeian K, Brooks HL, Warltier DC) Am Heart J 1992 Mar;123(3):566-74 PMID: 1539507 SCOPUS ID: 2-s2.0-0026606047 03/01/1992 15 Citations

Alteration of canine left ventricular diastolic function by intravenous anesthetics in vivo. Ketamine and propofol. (Pagel PS, Schmeling WT, Kampine JP, Warltier DC) Anesthesiology 1992 Mar;76(3):419-25 PMID: 1539854 SCOPUS ID: 2-s2.0-0026510606 03/01/1992 49 Citations

Differential relaxant effect of high concentrations of intravenous anesthetics on endothelin-constricted proximal and distal canine coronary arteries. (Coughlan MG, Flynn NM, Kenny D, Warltier DC, Kampine JP) Anesth Analg 1992 Mar;74(3):378-83 PMID: 1539819 SCOPUS ID: 2-s2.0-0026582940 03/01/1992 29 Citations

Cardioprotective effects of nicorandil. (Gross GJ, Auchampach JA, Maruyama M, Warltier DC, Pieper GM) J Cardiovasc Pharmacol 1992;20 Suppl 3:S22-8 PMID: 1282172 SCOPUS ID: 2-s2.0-0026641143 01/01/1992 83 Citations

Endothelium-dependent vasodilation of canine coronary collateral vessels. (Flynn NM, Kenny D, Pelc LR, Warltier DC, Bosnjak ZJ, Kampine JP) Am J Physiol 1991 Dec;261(6 Pt 2):H1797-801 PMID: 1750535 SCOPUS ID: 2-s2.0-0026315804 12/01/1991 20 Citations

Isoflurane causes only minimal increases in coronary blood flow independent of oxygen demand. (Kenny D, Proctor LT, Schmeling WT, Kampine JP, Warltier DC) Anesthesiology 1991 Oct;75(4):640-9 PMID: 1928773 SCOPUS ID: 2-s2.0-0026402951 10/01/1991 8 Citations

The effects of the stereoisomers of the alpha 2-adrenergic agonist medetomidine on systemic and coronary hemodynamics in conscious dogs. (Schmeling WT, Kampine JP, Roerig DL, Warltier DC) Anesthesiology 1991 Sep;75(3):499-511 PMID: 1679615 SCOPUS ID: 2-s2.0-0025999215 09/01/1991 93 Citations

Alteration of left ventricular diastolic function by desflurane, isoflurane, and halothane in the chronically instrumented dog with autonomic nervous system blockade. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1991 Jun;74(6):1103-14 PMID: 2042762 SCOPUS ID: 2-s2.0-0025913682 06/01/1991 76 Citations

Mechanism of coronary vasodilation produced by bradykinin. (Pelc LR, Gross GJ, Warltier DC) Circulation 1991 Jun;83(6):2048-56 PMID: 1645623 SCOPUS ID: 2-s2.0-0025833323 06/01/1991 89 Citations

Influence of volatile anesthetics on myocardial contractility in vivo: desflurane versus isoflurane. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1991 May;74(5):900-7 PMID: 2021208 SCOPUS ID: 2-s2.0-0025816383 05/01/1991 70 Citations

Dipyridamole-induced decrement of functional recovery of postischemic reperfused myocardium in conscious dogs with well-developed coronary collateral circulation. (Kenny D, Wynsen JC, Brooks HL, Warltier DC) Am Heart J 1991 May;121(5):1339-47 PMID: 2017968 SCOPUS ID: 2-s2.0-0025761914 05/01/1991 7 Citations

Regional myocardial function after repetitive brief episodes of ischemia: effect of altering the duration of the reperfusion period. (Wynsen JC, Kenny D, Brooks HL, Warltier DC) Am Heart J 1991 May;121(5):1331-8 PMID: 2017967 SCOPUS ID: 2-s2.0-0025892471 05/01/1991 11 Citations

Steal-prone coronary circulation in chronically instrumented dogs: isoflurane versus adenosine. (Hartman JC, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1991 Apr;74(4):744-56 PMID: 2008956 SCOPUS ID: 2-s2.0-0025841834 04/01/1991 31 Citations

Estimation of myocardial infarct size with ultrasonic tissue characterization. (Sagar KB, Pelc LR, Rhyne TL, Howard J, Warltier DC) Circulation 1991 Apr;83(4):1419-28 PMID: 2013158 SCOPUS ID: 2-s2.0-0025905538 04/01/1991 16 Citations

Influence of desflurane on regional distribution of coronary blood flow in a chronically instrumented canine model of multivessel coronary artery obstruction. (Hartman JC, Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesth Analg 1991 Mar;72(3):289-99 PMID: 1994756 SCOPUS ID: 2-s2.0-0025754166 03/01/1991 30 Citations

Comparison of the systemic and coronary hemodynamic actions of desflurane, isoflurane, halothane, and enflurane in the chronically instrumented dog. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1991 Mar;74(3):539-51 PMID: 2001033 SCOPUS ID: 2-s2.0-0025907107 03/01/1991 143 Citations

Prolongation of the QT interval by enflurane, isoflurane, and halothane in humans. (Schmeling WT, Warltier DC, McDonald DJ, Madsen KE, Atlee JL, Kampine JP) Anesth Analg 1991 Feb;72(2):137-44 PMID: 1898684 SCOPUS ID: 2-s2.0-0025872679 02/01/1991 127 Citations

Alterations in collateral blood flow produced by isoflurane in a chronically instrumented canine model of multivessel coronary artery disease. (Hartman JC, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1991 Jan;74(1):120-33 PMID: 1986637 SCOPUS ID: 2-s2.0-0025728205 01/01/1991 25 Citations

Oral dexmedetomidine attenuates hemodynamic responses during emergence from general anesthesia in chronically instrumented dogs. (Proctor LT, Schmeling WT, Roerig D, Kampine JP, Warltier DC) Anesthesiology 1991 Jan;74(1):108-14 PMID: 1670911 SCOPUS ID: 2-s2.0-0025907777 01/01/1991 24 Citations

Actions of isoflurane on myocardial perfusion in chronically instrumented dogs with poor, moderate, or well-developed coronary collaterals. (Hartman JC, Kampine JP, Schmeling WT, Warltier DC) J Cardiothorac Anesth 1990 Dec;4(6):715-25 PMID: 2131901 SCOPUS ID: 2-s2.0-0025601431 12/01/1990 6 Citations

Effects of nitrous oxide on myocardial contractility as evaluated by the preload recruitable stroke work relationship in chronically instrumented dogs. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1990 Dec;73(6):1148-57 PMID: 2147368 SCOPUS ID: 2-s2.0-0025672651 12/01/1990 20 Citations

A model of multivessel coronary artery disease using conscious, chronically instrumented dogs. (Hartman JC, Warltier DC) J Pharmacol Methods 1990 Dec;24(4):297-310 PMID: 2292881 SCOPUS ID: 2-s2.0-0025668688 12/01/1990 6 Citations

Role of ultrasonic tissue characterization to distinguish reversible from irreversible myocardial injury. (Sagar KB, Pelc LR, Rhyne TL, Komorowski RA, Wann LS, Warltier DC) J Am Soc Echocardiogr 1990;3(6):471-7 PMID: 1703768 SCOPUS ID: 2-s2.0-0025517701 11/01/1990 18 Citations

Volatile anesthetics and regional myocardial perfusion in chronically instrumented dogs: halothane versus isoflurane in a single-vessel disease model with enhanced collateral development. (Hartman JC, Kampine JP, Schmeling WT, Warltier DC) J Cardiothorac Anesth 1990 Oct;4(5):588-603 PMID: 2132138 SCOPUS ID: 2-s2.0-0025018250 10/01/1990 7 Citations

Comparison of end-systolic pressure-length relations and preload recruitable stroke work as indices of myocardial contractility in the conscious and anesthetized, chronically instrumented dog. (Pagel PS, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1990 Aug;73(2):278-90 PMID: 2382851 SCOPUS ID: 2-s2.0-0025143693 08/01/1990 46 Citations

Quantitative ultrasonic assessment of normal and ischaemic myocardium with an acoustic microscope: relationship to integrated backscatter. (Sagar KB, Agemura DH, O'Brien WD Jr, Pelc LR, Rhyne TL, Wann LS, Komorowski RA, Warltier DC) Cardiovasc Res 1990 Jun;24(6):447-55 PMID: 2201447 SCOPUS ID: 2-s2.0-85047680114 06/01/1990 13 Citations

Enhanced alpha-adrenergic vasoconstriction by n-3 fatty acids in conscious dogs. (Kenny D, Brooks HL, Warltier DC) Am J Physiol 1990 Jun;258(6 Pt 2):H1660-7 PMID: 1972867 SCOPUS ID: 2-s2.0-0025277216 06/01/1990 13 Citations

Alteration of endothelium-dependent distribution of myocardial blood flow after coronary occlusion and reperfusion. (Pelc LR, Garancis JC, Gross GJ, Warltier DC) Circulation 1990 Jun;81(6):1928-37 PMID: 2344685 SCOPUS ID: 2-s2.0-0025298187 06/01/1990 31 Citations

Calcium channel modulation of alpha 1- and alpha 2-adrenergic pressor responses in conscious and anesthetized dogs. (Kenny D, Pelc LR, Brooks HL, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1990 May;72(5):874-81 PMID: 1692673 SCOPUS ID: 2-s2.0-0025350946 05/01/1990 9 Citations

Vasodilator actions of interleukin-1 in the canine coronary circulation. (Kenny D, McCarthy-Kenny G, Pelc LR, Cheung HS, Brooks HL, Warltier DC) Basic Res Cardiol 1990;85(3):279-84 PMID: 2383221 SCOPUS ID: 2-s2.0-0025372986 05/01/1990 9 Citations

Ultrasonic tissue characterization of normal and ischemic myocardium. (Sagar KB, Pelc LR, Saeian K, Rhyne TL, Wann LS, Warltier DC) Echocardiography 1990 Jan;7(1):11-9 PMID: 10149187 SCOPUS ID: 2-s2.0-0025278033 12/10/1989 1 Citation

Alterations of alpha 1 and alpha 2 adrenoceptor-mediated pressor responses by halothane and isoflurane anesthesia. (Kenny D, Pelc LR, Brooks HL, Kampine JP, Schmeling WT, Warltier DC) Anesthesiology 1989 Aug;71(2):224-34 PMID: 2569281 SCOPUS ID: 2-s2.0-0024329887 08/01/1989 18 Citations

Negative chronotropic actions of sufentanil and vecuronium in chronically instrumented dogs pretreated with propranolol and/or diltiazem. (Schmeling WT, Kampine JP, Warltier DC) Anesth Analg 1989 Jul;69(1):4-14 PMID: 2568103 SCOPUS ID: 2-s2.0-0024790422 07/01/1989 26 Citations

Reduction of myocardial ischemia-reperfusion injury by KT-362, a new intracellular calcium antagonist in anesthetized dogs. (Pelc LR, Farber NE, Warltier DC, Gross GJ) J Cardiovasc Pharmacol 1989 Apr;13(4):586-93 PMID: 2470996 SCOPUS ID: 2-s2.0-0024601545 04/01/1989 13 Citations

Improvement in functional recovery of stunned canine myocardium by long-term pretreatment with oral propranolol. (al-Wathiqui MH, Farber N, Pelc L, Gross GJ, Brooks HL, Warltier DC) Am Heart J 1989 Apr;117(4):791-8 PMID: 2929396 SCOPUS ID: 2-s2.0-0024564338 04/01/1989 6 Citations

Effects of nisoldipine on coronary collateral perfusion and hemodynamics in chronically instrumented dogs. (Kenny D, Hartman JC, Brooks HL, Warltier DC) Pharmacology 1989;38(4):263-71 PMID: 2755966 SCOPUS ID: 2-s2.0-0024580215 01/01/1989

Alpha adrenoceptor subtypes and receptor reserve in human versus canine saphenous vein: sensitivity to blockade by nitroglycerin. (Eskinder H, Hillard CJ, Olinger GN, Christensen CW, Baker JE, Warltier DC, Gross GJ) J Pharmacol Exp Ther 1988 Dec;247(3):941-8 PMID: 2905005 SCOPUS ID: 2-s2.0-0024269976 12/01/1988 12 Citations

Cyclical carotid artery flow reduction in conscious dogs: effect of a new thromboxane receptor antagonist. (al-Wathiqui MH, Hartman JC, Brooks HL, Gross GJ, Warltier DC) Am Heart J 1988 Dec;116(6 Pt 1):1482-7 PMID: 3195431 SCOPUS ID: 2-s2.0-0024215706 12/01/1988 3 Citations

Recovery of contractile function of stunned myocardium in chronically instrumented dogs is enhanced by halothane or isoflurane. (Warltier DC, al-Wathiqui MH, Kampine JP, Schmeling WT) Anesthesiology 1988 Oct;69(4):552-65 PMID: 3177915 SCOPUS ID: 2-s2.0-0023752844 10/01/1988 210 Citations

Steroid-induced enhancement of functional recovery of postischemic, reperfused myocardium in conscious dogs. (Wynsen JC, Preuss KC, Gross GJ, Brooks HL, Warltier DC) Am Heart J 1988 Oct;116(4):915-25 PMID: 3051986 SCOPUS ID: 2-s2.0-0023693367 10/01/1988 12 Citations

Prolongation of the QT interval by volatile anesthetics in chronically instrumented dogs. (Riley DC, Schmeling WT, al-Wathiqui MH, Kampine JP, Warltier DC) Anesth Analg 1988 Aug;67(8):741-9 PMID: 3394961 SCOPUS ID: 2-s2.0-0023803049 08/01/1988 48 Citations

Induction of cyclic flow reduction in the coronary, carotid, and femoral arteries of conscious, chronically instrumented dogs. A model for investigating the role of platelets in severely constricted arteries. (Al-Wathiqui MH, Hartman JC, Brooks HL, Warltier DC) J Pharmacol Methods 1988 Aug;20(1):85-92 PMID: 3411977 SCOPUS ID: 2-s2.0-0023689156 08/01/1988 5 Citations

Mechanisms of enhanced canine subendocardial perfusion. A comparison of adenosine triphosphate and sodium nitroprusside. (Pelc LR, Gross GJ, Kampine JP, Warltier DC) Anesth Analg 1988 Jun;67(6):514-20 PMID: 3259847 SCOPUS ID: 2-s2.0-0023925764 06/01/1988 4 Citations

Muscarinic receptor subtypes mediating myocardial blood flow redistribution. (Pelc LR, Daemmgen JW, Gross GJ, Warltier DC) J Cardiovasc Pharmacol 1988 Apr;11(4):424-31 PMID: 2453745 SCOPUS ID: 2-s2.0-0023848028 04/01/1988 9 Citations

Comparative effects of inotropic agents on coronary and systemic hemodynamics of conscious dogs: actions of milrinone, dopamine, ouabain and MCI-154. (Al-Wathiqui MH, Shimshak TM, Brooks HL, Preuss KC, Wynsen JC, Gross GJ, Warltier DC) Pharmacology 1988;36(4):217-27 PMID: 3380877 SCOPUS ID: 2-s2.0-0023832485 01/01/1988 5 Citations

Hemodynamic and electrocardiographic actions of the new intracellular calcium antagonist, KT-362, in the conscious dog. (Hartman JC, Al-Wathiqui MH, Brooks HL, Gross GJ, Warltier DC) Pharmacology 1988;37(6):376-84 PMID: 3244744 SCOPUS ID: 2-s2.0-0024240426 01/01/1988 3 Citations

Improvement of postischemic, contractile function by the calcium channel blocking agent nitrendipine in conscious dogs. (Warltier DC, Gross GJ, Brooks HL, Preuss KC) J Cardiovasc Pharmacol 1988;12 Suppl 4:S120-4 PMID: 2468853 SCOPUS ID: 2-s2.0-0024267950 01/01/1988 18 Citations

A canine model of thrombin-induced coronary artery thrombosis: effects of intracoronary streptokinase on regional myocardial blood flow, contractile function, and infarct size. (Warltier DC, Lamping KA, Pelc LR, Gross GJ) J Pharmacol Methods 1987 Dec;18(4):305-18 PMID: 3695539 SCOPUS ID: 2-s2.0-0023205266 12/01/1987 8 Citations

Specific bradycardic agents, a new therapeutic modality for anesthesiology: hemodynamic effects of UL-FS 49 and propranolol in conscious and isoflurane-anesthetized dogs. (Riley DC, Gross GJ, Kampine JP, Warltier DC) Anesthesiology 1987 Nov;67(5):707-16 PMID: 3674471 SCOPUS ID: 2-s2.0-0023444617 11/01/1987 26 Citations

Comparative effects of nicorandil, a nicotinamide nitrate derivative, and nifedipine on myocardial reperfusion injury in dogs. (Gross GJ, Warltier DC, Hardman HF) J Cardiovasc Pharmacol 1987 Nov;10(5):535-42 PMID: 2447402 SCOPUS ID: 2-s2.0-0023445922 11/01/1987 24 Citations

Time course of recovery of "stunned" myocardium following variable periods of ischemia in conscious and anesthetized dogs. (Preuss KC, Gross GJ, Brooks HL, Warltier DC) Am Heart J 1987 Oct;114(4 Pt 1):696-703 PMID: 2959132 SCOPUS ID: 2-s2.0-0023629330 10/01/1987 65 Citations

Changes in adrenergic pressor responses by calcium channel modulation in conscious dogs. (Wynsen JC, Gross GJ, Brooks HL, Warltier DC) Am J Physiol 1987 Sep;253(3 Pt 2):H531-9 PMID: 2443022 SCOPUS ID: 2-s2.0-0023612062 09/01/1987 8 Citations

Cardiovascular actions of a new dihydropyridine calcium antagonist, 8363-S: comparison with nifedipine and nicardipine in awake, unsedated dogs. (Wynsen JC, Shimshak TM, Preuss KC, Hardman HF, Warltier DC) J Cardiovasc Pharmacol 1987 Jul;10(1):30-7 PMID: 2441151 SCOPUS ID: 2-s2.0-0023251434 07/01/1987 4 Citations

Preferential increase in subendocardial perfusion produced by endothelium-dependent vasodilators. (Pelc LR, Gross GJ, Warltier DC) Circulation 1987 Jul;76(1):191-200 PMID: 3594767 SCOPUS ID: 2-s2.0-0023278756 07/01/1987 26 Citations

Differential effects of nifedipine, nicorandil and nitroglycerin on the pressor responses elicited by selective alpha-1 and alpha-adrenoceptor agonists in conscious dogs. (Wynsen JC, Gross GJ, Brooks HL, Warltier DC) J Pharmacol Exp Ther 1987 Jun;241(3):846-54 PMID: 2885410 SCOPUS ID: 2-s2.0-0023359810 06/01/1987 3 Citations

Regional distribution of blood flow at the onset of right ventricular diastolic collapse during cardiac tamponade. (Bernath GA, Cogswell TL, Shimshak TM, Warltier DC, Klopfenstein HS) Am Heart J 1987 May;113(5):1129-32 PMID: 3578007 SCOPUS ID: 2-s2.0-0023198182 05/01/1987 4 Citations

Intramyocardial variability in integrated backscatter: effects of coronary occlusion and reperfusion. (Sagar KB, Rhyne TL, Warltier DC, Pelc L, Wann LS) Circulation 1987 Feb;75(2):436-42 PMID: 3542284 02/01/1987

Comparative effects of nicorandil, nitroglycerin, nicotinic acid, and SG-86 on the metabolic status and functional recovery of the ischemic-reperfused myocardium. (Gross GJ, Pieper GM, Warltier DC) J Cardiovasc Pharmacol 1987;10 Suppl 8:S76-84 PMID: 2447429 SCOPUS ID: 2-s2.0-0023518719 01/01/1987 25 Citations

Stimulation of myocardium during reperfusion injury by a new inotrope-vasodilator agent, MCI-154. (Wynsen JC, Shimshak TM, Preuss KC, Gross GJ, Brooks HL, Warltier DC) Fundam Clin Pharmacol 1987;1(5):335-45 PMID: 3443426 SCOPUS ID: 2-s2.0-0023554128 01/01/1987 3 Citations

Effects of intracoronary Bay k 8644, a calcium channel agonist, in anesthetized dogs. (Pelc LR, Gross GJ, Brooks HL, Warltier DC) J Cardiovasc Pharmacol 1986;8(6):1223-8 PMID: 2434750 SCOPUS ID: 2-s2.0-0022970489 11/01/1986 5 Citations

Recovery of contractile function in post-ischaemic reperfused myocardium of conscious dogs: influence of nicorandil, a new antianginal agent. (Shimshak TM, Preuss KC, Gross GJ, Brooks HL, Warltier DC) Cardiovasc Res 1986 Aug;20(8):621-6 PMID: 2947685 SCOPUS ID: 2-s2.0-85047679535 08/01/1986 27 Citations

Changes in regional myocardial perfusion by muscarinic receptor subtypes in dogs. (Pelc LR, Gross GJ, Warltier DC) Cardiovasc Res 1986 Jul;20(7):482-9 PMID: 3779744 SCOPUS ID: 2-s2.0-85047676214 07/01/1986 7 Citations

Effects of KB-944, a novel calcium antagonist, in several models of canine myocardial ischemia. (Pelc LR, Gross GJ, Warltier DC) J Pharmacol Exp Ther 1986 Jul;238(1):113-8 PMID: 3723394 SCOPUS ID: 2-s2.0-0022491940 07/01/1986 4 Citations

Beneficial actions of superoxide dismutase and catalase in stunned myocardium of dogs. (Gross GJ, Farber NE, Hardman HF, Warltier DC) Am J Physiol 1986 Mar;250(3 Pt 2):H372-7 PMID: 3953834 SCOPUS ID: 2-s2.0-0022510273 03/01/1986 216 Citations

Importance of retrograde coronary flow in the prediction of experimental myocardial infarct size. (Warltier DC, Zyvoloski MG, Gross GJ, Brooks HL) Cardiology 1986;73(6):333-46 PMID: 3791333 SCOPUS ID: 2-s2.0-0023035460 01/01/1986 4 Citations

Slow channel calcium activators, a new group of pharmacological agents. (Preuss KC, Gross GJ, Brooks HL, Warltier DC) Life Sci 1985 Oct 07;37(14):1271-8 PMID: 2413326 SCOPUS ID: 2-s2.0-0021827839 10/07/1985 33 Citations

Enhanced subendocardial perfusion distal to a flow-limiting coronary artery stenosis in dogs: comparative effects of nicorandil, a potential new antianginal agent, and nitroglycerin. (Gross GJ, Warltier DC, Hardman HF, Lamping KA) J Cardiovasc Pharmacol 1985;7(5):977-82 PMID: 2413311 SCOPUS ID: 2-s2.0-0021970511 09/01/1985 10 Citations

Effects of AQ-AH 208, a new specific bradycardic agent, on myocardial ischemia-reperfusion injury in anesthetized dogs. (Gross GJ, Warltier DC, Daemmgen JW) J Cardiovasc Pharmacol 1985;7(5):929-36 PMID: 2413303 SCOPUS ID: 2-s2.0-0021932474 09/01/1985 11 Citations

Hemodynamic actions of nicorandil, a new antianginal agent, in the conscious dog. (Preuss KC, Gross GJ, Brooks HL, Warltier DC) J Cardiovasc Pharmacol 1985;7(4):709-14 PMID: 2410712 SCOPUS ID: 2-s2.0-0021877174 07/01/1985 38 Citations

Positive inotropic actions of the calcium channel stimulator, Bay k 8644, in awake, unsedated dogs. (Preuss KC, Brooks HL, Gross GJ, Warltier DC) Basic Res Cardiol 1985;80(3):326-32 PMID: 2411255 SCOPUS ID: 2-s2.0-0021809478 05/01/1985 16 Citations

Cardiotonic effects of anthopleurin-A (AP-A), a polypeptide from a sea anemone, in dogs with a coronary artery stenosis. (Gross GJ, Warltier DC, Hardman HF, Shibata S) Eur J Pharmacol 1985 Apr 02;110(2):271-6 PMID: 3987818 SCOPUS ID: 2-s2.0-0021814522 04/02/1985 19 Citations

Direct cardiac actions of the H2 receptor agonists, impromidine and dimaprit. (Pelc LR, Christensen CW, Gross GJ, Warltier DC) Eur J Pharmacol 1985 Jan 08;107(3):379-84 PMID: 3156752 SCOPUS ID: 2-s2.0-0021951650 01/08/1985 1 Citation

Cardiac and systemic hemodynamic actions of the slow channel calcium blocking agent, KB-944. (Pelc LR, Gross GJ, Warltier DC) Gen Pharmacol 1985;16(6):585-90 PMID: 4085780 SCOPUS ID: 2-s2.0-0022346041 01/01/1985 1 Citation

Cardiovascular effects of the nifedipine analog, CGP 28 392, in the conscious dog. (Preuss KC, Cheung NL, Brooks HL, Warltier DC) J Cardiovasc Pharmacol 1984;6(5):949-53 PMID: 6209505 SCOPUS ID: 2-s2.0-0021193999 09/01/1984 20 Citations

A microcomputer-based package for determination of regional and global cardiac function and coronary hemodynamics. (Wilkison DM, Preuss KC, Warltier DC) J Pharmacol Methods 1984 Aug;12(1):59-67 PMID: 6536815 SCOPUS ID: 2-s2.0-0021248222 08/01/1984 18 Citations

Comparative actions of dihydropyridine slow channel calcium blocking agents in conscious dogs: alterations in baroreflex sensitivity. (Warltier DC, Zyvoloski MG, Gross GJ, Brooks HL) J Pharmacol Exp Ther 1984 Aug;230(2):376-82 PMID: 6747841 SCOPUS ID: 2-s2.0-0021173653 08/01/1984 24 Citations

Comparative actions of dihydropyridine slow channel calcium blocking agents in conscious dogs: systemic and coronary hemodynamics with and without combined beta adrenergic blockade. (Warltier DC, Zyvoloski MG, Gross GJ, Brooks HL) J Pharmacol Exp Ther 1984 Aug;230(2):367-75 PMID: 6146711 SCOPUS ID: 2-s2.0-0021152589 08/01/1984 40 Citations

Effects of nicorandil, a new antianginal agent, and nifedipine on collateral blood flow in a chronic coronary occlusion model. (Lamping KA, Warltier DC, Hardman HF, Gross GJ) J Pharmacol Exp Ther 1984 May;229(2):359-63 PMID: 6232374 SCOPUS ID: 2-s2.0-0021358760 05/01/1984 32 Citations

Effects of nicorandil and nifedipine on protection of ischemic myocardium. (Lamping KA, Christensen CW, Pelc LR, Warltier DC, Gross GJ) J Cardiovasc Pharmacol 1984;6(3):536-42 PMID: 6202983 SCOPUS ID: 2-s2.0-0021192059 05/01/1984 77 Citations

Selective improvement in subendocardial perfusion distal to a flow-limiting coronary artery stenosis: effects of the new calcium channel blocking agent, FR 34235, nifedipine and diltiazem. (Gross GJ, Warltier DC) J Pharmacol Exp Ther 1984 Mar;228(3):531-6 PMID: 6707908 SCOPUS ID: 2-s2.0-0021330061 03/01/1984 16 Citations

Effects of three bradycardiac drugs on regional myocardial blood flow and function in areas distal to a total or partial coronary occlusion in dogs. (Gross GJ, Lamping KG, Warltier DC, Hardman HF) Circulation 1984 Feb;69(2):391-9 PMID: 6690105 SCOPUS ID: 2-s2.0-0021325024 02/01/1984 30 Citations

Contrasting effects of pharmacologic vasodilation on true collateral and overlap perfusion in ischemic myocardium. (Keelan KE, Gross GJ, Brooks HL, Warltier DC) Gen Pharmacol 1984;15(6):471-7 PMID: 6526259 SCOPUS ID: 2-s2.0-0021713295 01/01/1984

Comparative effects of two slow channel calcium entry blockers, FR 34235 and nifedipine, on true coronary collateral blood flow. (Gross GJ, Warltier DC, Hardman HF) J Cardiovasc Pharmacol 1984;6(1):61-7 PMID: 6199613 SCOPUS ID: 2-s2.0-0021369542 01/01/1984 21 Citations

Transmural gradient of coronary blood flow following dihydropyridine calcium antagonists and other vasodilator drugs. (Warltier DC, Hardman HF, Brooks HL, Gross GJ) Basic Res Cardiol 1983;78(6):644-53 PMID: 6661160 SCOPUS ID: 2-s2.0-0021061222 11/01/1983 6 Citations

Coronary hemodynamics and subendocardial perfusion distal to stenoses. (Warltier DC, Buck JD, Brooks HL, Gross GJ) Int J Cardiol 1983 Sep;4(2):173-83 PMID: 6629531 SCOPUS ID: 2-s2.0-0020618290 09/01/1983 5 Citations

Effects of histamine receptor stimulation on regional myocardial blood flow. (Christensen CW, Gross GJ, Hardman HF, Brooks HL, Warltier DC) Am J Physiol 1983 Sep;245(3):H461-7 PMID: 6225343 SCOPUS ID: 2-s2.0-0020824831 09/01/1983 10 Citations

The slow-channel calcium blocking agent, nitrendipine, and coronary collateral blood flow. (Warltier DC, Lamping KA, Zyvoloski MG, Gross GJ, Brooks HL) J Cardiovasc Pharmacol 1983;5(2):272-7 PMID: 6188902 SCOPUS ID: 2-s2.0-0020692962 03/01/1983 6 Citations

The effect of diltiazem, a calcium channel blocking agent, on vasoconstrictor responses to norepinephrine, serotonin and potassium depolarization in canine coronary and femoral arteries. (Mullett M, Gharaibeh M, Warltier DC, Gross GJ) Gen Pharmacol 1983;14(2):259-64 PMID: 6840509 SCOPUS ID: 2-s2.0-0020700973 01/01/1983 9 Citations

Comparative effects of FR 34235, a new slow channel calcium blocker, and nifedipine on hemodynamics and myocardial oxygen consumption in the anesthetized dog. (Gross GJ, Warltier DC, Hardman HF) Gen Pharmacol 1983;14(6):677-80 PMID: 6662348 SCOPUS ID: 2-s2.0-0021049513 01/01/1983 14 Citations

Subendocardial versus transmural myocardial infarction: relationship to the collateral circulation in canine and porcine hearts. (Warltier DC, Zyvoloski MG, Gross GJ, Brooks HL) Can J Physiol Pharmacol 1982 Dec;60(12):1700-6 PMID: 7165863 SCOPUS ID: 2-s2.0-0020356236 12/01/1982 19 Citations

Role of autoregulation in the beneficial action of propranolol on ischemic blood flow distribution and stenosis severity in the canine myocardium. (Gross GJ, Buck JD, Warltier DC, Hardman HF) J Pharmacol Exp Ther 1982 Sep;222(3):635-40 PMID: 7108768 SCOPUS ID: 2-s2.0-0019988255 09/01/1982 15 Citations

Myocardial perfusion distal to an acute or chronic coronary artery occlusion: effects of diltiazem and nifedipine. (Zyvoloski MG, Brooks HL, Gross GJ, Warltier DC) J Pharmacol Exp Ther 1982 Aug;222(2):494-500 PMID: 7097568 SCOPUS ID: 2-s2.0-0019986261 08/01/1982 33 Citations

Beneficial effects of the dihydropyridine calcium antagonist, FR 34235, in a chronic coronary occlusion model. (Warltier DC, Zyvoloski MG, Brooks HL, Gross GJ) Eur J Pharmacol 1982 May 07;80(1):149-53 PMID: 7095001 SCOPUS ID: 2-s2.0-0020060513 05/07/1982 17 Citations

Separation of overlap and collateral perfusion of ischemic canine myocardium: important considerations in the analysis of vasodilator-induced coronary steal. (Gross GJ, Buck JD, Warltier DC, Hardman HF) J Cardiovasc Pharmacol 1982;4(2):254-63 PMID: 6175809 SCOPUS ID: 2-s2.0-0020053055 03/01/1982 17 Citations

Determination of experimental myocardial infarct size. (Warltier DC, Zyvoloski MG, Gross GJ, Hardman HF, Brooks HL) J Pharmacol Methods 1981 Nov;6(3):199-210 PMID: 7329069 SCOPUS ID: 2-s2.0-0019847146 11/01/1981 80 Citations

Changes in ischemic blood flow distribution and dynamic severity of a coronary stenosis induced by beta blockade in the canine heart. (Buck JD, Hardman HF, Warltier DC, Gross GJ) Circulation 1981 Oct;64(4):708-15 PMID: 6115724 SCOPUS ID: 2-s2.0-0019520743 10/01/1981 52 Citations

Redistribution of myocardial blood flow distal to a dynamic coronary arterial stenosis by sympathomimetic amines: comparison of dopamine, dobutamine and isoproterenol. (Warltier DC, Zyvoloski M, Gross GJ, Hardman HF, Brooks HL) Am J Cardiol 1981 Aug;48(2):269-79 PMID: 7270436 SCOPUS ID: 2-s2.0-0019465365 08/01/1981 62 Citations

Blood flow in normal and acutely ischemic myocardium after verapamil, diltiazem and nisoldipine (Bay k 5552), a new dihydropyridine calcium antagonist. (Warltier DC, Meils CM, Gross GJ, Brooks HL) J Pharmacol Exp Ther 1981 Jul;218(1):296-302 PMID: 7248040 SCOPUS ID: 2-s2.0-0019502585 07/01/1981 80 Citations

Coronary steal in four models of single or multiple vessel obstruction in dogs. (Gross GJ, Warltier DC) Am J Cardiol 1981 Jul;48(1):84-92 PMID: 7246448 SCOPUS ID: 2-s2.0-0019462364 07/01/1981 82 Citations

Transmural distribution of blood flow during activation of coronary muscarinic receptors. (Gross GJ, Buck JD, Warltier DC) Am J Physiol 1981 Jun;240(6):H941-6 PMID: 7246756 SCOPUS ID: 2-s2.0-0019583571 06/01/1981 28 Citations

Pharmacologic- vs. ischemia-induced coronary artery vasodilation. (Warltier DC, Gross GJ, Brooks HL) Am J Physiol 1981 May;240(5):H767-74 PMID: 7235035 SCOPUS ID: 2-s2.0-0019568288 05/01/1981 53 Citations

Effects of sotalol and vagal stimulation on ischemic myocardial blood flow distribution in the canine heart. (Buck JD, Warltier DC, Hardman HF, Gross GJ) J Pharmacol Exp Ther 1981 Feb;216(2):347-51 PMID: 7463353 SCOPUS ID: 2-s2.0-0019405348 02/01/1981 15 Citations

Reduction of myocardial infarct size by the calcium antagonist fr 7534. (Meils CM, Gross GJ, Brooks HL, Warltier DC) Cardiology 1981;68(3):146-60 PMID: 7317884 SCOPUS ID: 2-s2.0-0019481512 01/01/1981 9 Citations

Relaxation of potassium-depolarized canine, bovine and porcine large coronary arteries by nitroglycerin, chromonar and two dihydropyridine calcium antagonists. (Gross GJ, Diemer MJ, Warltier DC, Hardman HF) Gen Pharmacol 1981;12(3):199-204 PMID: 6786956 SCOPUS ID: 2-s2.0-0019480749 01/01/1981 9 Citations

Comparative effects of a new calcium antagonist, FR 7534, nitroglycerin, and dipyridamole on regional myocardial blood flow and cardiac contractility during partial coronary artery occlusion in the dog. (Gross GJ, Warltier DC, Jolly SR, Hardman HF) J Cardiovasc Pharmacol 1980;2(6):797-813 PMID: 6160329 SCOPUS ID: 2-s2.0-0018948623 11/01/1980 6 Citations

Subepicardial steal and reduction of myocardial oxygen consumption by adenosine. (Warltier DC, Gross GJ, Hardman HF) Eur J Pharmacol 1980 Oct 03;67(1):101-4 PMID: 7418726 SCOPUS ID: 2-s2.0-0018929857 10/03/1980 3 Citations

Coronary steal-induced increase in myocardial infarct size after pharmacologic coronary vasodilation. (Warltier DC, Gross GJ, Brooks HL) Am J Cardiol 1980 Jul;46(1):83-90 PMID: 7386397 SCOPUS ID: 2-s2.0-0018837719 07/01/1980 32 Citations

Protection of ischemic myocardium: comparison of effects of propranolol, bevantolol and N-dimethyl propranolol on infarct size following coronary artery occlusion in anesthetized dogs. (Warltier DC, Gross GJ, Jesmok GJ, Brooks HL, Hardman HF) Cardiology 1980;66(3):133-46 PMID: 6105914 SCOPUS ID: 2-s2.0-0018850091 01/01/1980 16 Citations

Comparative effects of cardioselective versus noncardioselective beta blockade on subendocardial blood flow and contractile function in ischemic myocardium. (Buck JD, Gross GJ, Warltier DC, Jolly SR, Hardman HF) Am J Cardiol 1979 Oct;44(4):657-63 PMID: 39449 SCOPUS ID: 2-s2.0-0018700934 10/01/1979 38 Citations

Transmural perfusion gradients distal to various degrees of coronary artery stenosis during resting flow or at maximal vasodilation. (Warltier DC, Hardman HF, Gross GJ) Basic Res Cardiol 1979;74(5):494-508 PMID: 526256 SCOPUS ID: 2-s2.0-0018622390 09/01/1979 12 Citations

Beneficial actions of bevantolol on subendocardial blood flow and contractile function in ischemic myocardium. (Gross GJ, Buck JD, Warltier DC, Hardman HF) J Cardiovasc Pharmacol 1979;1(1):139-47 PMID: 94375 SCOPUS ID: 2-s2.0-0018703011 01/01/1979 23 Citations

Transmural triglycerides in acute myocardial ischaemia. (Jesmok GJ, Warltier DC, Gross GJ, Hardman HF) Cardiovasc Res 1978 Nov;12(11):659-65 PMID: 750079 SCOPUS ID: 2-s2.0-85047668609 11/01/1978 13 Citations

Effect of propranolol on enzymatic and histochemical estimates of infarct size in experimental myocardial infarction. (Jesmok GJ, Warltier DC, Gross GJ, Hardman HF) Basic Res Cardiol 1978;73(6):559-70 PMID: 747615 SCOPUS ID: 2-s2.0-0018124683 11/01/1978 12 Citations

Beneficial actions of N-dimethyl propranolol on myocardial oxygen balance and transmural perfusion gradients distal to a severe coronary artery stenosis in the canine heart. (Gross GJ, Warltier DC, Hardman HF) Circulation 1978 Oct;58(4):663-9 PMID: 688577 SCOPUS ID: 2-s2.0-0018132574 10/01/1978 17 Citations

Endocardial viability ratio on effect of nitroglycerin and propranolol on regional myocardial blood flow in intact canine hearts. (Gross GJ, Warltier DC) J Pharmacol Exp Ther 1977 Dec;203(3):664-74 PMID: 411913 SCOPUS ID: 2-s2.0-0017729901 12/01/1977 6 Citations

Technique for precise, graded arterial stenosis and occlusion. (Hosko MJ, Gross GJ, Warltier DC) Basic Res Cardiol 1977;72(6):651-9 PMID: 607934 SCOPUS ID: 2-s2.0-0017709581 11/01/1977 27 Citations

Intracoronary versus intravenous nitroglycerin on the transmural distribution of coronary blood flow. (Gross GJ, Warltier DC) Cardiovasc Res 1977 Nov;11(6):499-506 PMID: 414838 SCOPUS ID: 2-s2.0-85047671037 11/01/1977 13 Citations

Effect of ortho-iodo sodium benzoate on hemoglobin-oxygen affinity in normal and ischemic myocardium. (Gross GJ, Warltier DC, Hardman HF) J Pharmacol Exp Ther 1977 Oct;203(1):72-81 PMID: 909059 SCOPUS ID: 2-s2.0-0017706655 10/01/1977 9 Citations

The effect of ouabain on nutritional circulation and regional myocardial blood flow. (Gross GJ, Warltier DC, Hardman HF, Somani P) Am Heart J 1977 Apr;93(4):487-95 PMID: 842444 SCOPUS ID: 2-s2.0-0017359841 04/01/1977 18 Citations

Effect of propranolol on regional myocardial blood flow and oxygen consumption. (Warltier DC, Gross GJ, Hardman HF) J Pharmacol Exp Ther 1976 Aug;198(2):435-43 PMID: 948034 SCOPUS ID: 2-s2.0-0017133815 08/01/1976 24 Citations

The isolated supported canine heart: a model for the evaluation of drug effects on regional myocardial blood flow. (Warltier DC, Gross GJ, Hardman HF) J Pharmacol Exp Ther 1976 Aug;198(2):420-34 PMID: 948033 SCOPUS ID: 2-s2.0-0017080308 08/01/1976 10 Citations

Adenosine on myocardial oxygen consumption. (Gross GJ, Hardman HF, Warltier DC) Br J Pharmacol 1976 Jul;57(3):409-12 PMID: 974320 PMCID: PMC1667219 SCOPUS ID: 2-s2.0-0017080913 07/01/1976 11 Citations

Effect of propranolol and nitroglycerin on hemoglobin--oxygen affinity. (Gross GJ, Warltier DC, Hardman HF) Eur J Pharmacol 1976 Mar;36(1):267-71 PMID: 816659 SCOPUS ID: 2-s2.0-0017252966 03/01/1976 6 Citations

Effect of adenosine on myocardial oxygen balance. (Gross GJ, Warltier DC, Hardman HF) J Pharmacol Exp Ther 1976 Feb;196(2):445-54 PMID: 1255487 SCOPUS ID: 2-s2.0-0017295237 02/01/1976 15 Citations

Effect of right atrial pacing and nitroglycerin on myocardial oxygen balance. (Warltier DC, Gross GJ, Hardman HF) Eur J Pharmacol 1975 Nov;34(1):229-32 PMID: 826400 SCOPUS ID: 2-s2.0-0016837321 11/01/1975 3 Citations

Myocardial distribution of coronary blood flow in the isolated supported heart preparation. (Warltier DC, Hardman HF, Laddu AR, Somani P, Gross GJ) Cardiovasc Res 1975 Sep;9(5):634-9 PMID: 1201572 SCOPUS ID: 2-s2.0-0016760079 09/01/1975 12 Citations

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

David C. Warltier PhD

Emeritus Professor

Publications (351)