Medical College of Wisconsin
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Deepak Parashar PhD

Deepak Parashar PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Hematology and Oncology - Medicine
Program: Hematology


Publications (47)

  • Dysregulation of T cell response in the pathogenesis of inflammatory bowel disease (Chandwaskar R, Dalal R, Gupta S, Sharma A, Parashar D, Kashyap VK, Sohal JS, Tripathi SK) Scandinavian Journal of Immunology December 2024;100(6) SCOPUS ID: 2-s2.0-85205968041 12/01/2024       1 Citation
  • Circulating Extracellular Vesicles: An Effective Biomarker for Cancer Progression (Chatterjee M, Gupta S, Nag S, Rehman I, Parashar D, Maitra A, Das K) Frontiers in Bioscience - Landmark November 2024;29(11) SCOPUS ID: 2-s2.0-85209875740 11/01/2024    
  • Dysregulation of T cell response in the pathogenesis of inflammatory bowel disease. (Chandwaskar R, Dalal R, Gupta S, Sharma A, Parashar D, Kashyap VK, Sohal JS, Tripathi SK) Scand J Immunol 2024 Dec;100(6):e13412 PMID: 39394898 SCOPUS ID: 2-s2.0-85205968041 10/12/2024       1 Citation
  • The role of extracellular vesicles in the pathogenesis of gynecological cancer. (Chatterjee M, Gupta S, Mukherjee T, Parashar D, Kumar U, Maitra A, Das K) Front Oncol 2024;14:1477610 PMID: 39391238 PMCID: PMC11464257 SCOPUS ID: 2-s2.0-85206369417 10/11/2024    
  • MicroRNAs in extracellular vesicles: A potential role in cancer progression. (Parashar D, Mukherjee T, Gupta S, Kumar U, Das K) Cell Signal 2024 Sep;121:111263 PMID: 38897529 SCOPUS ID: 2-s2.0-85196483579 06/20/2024       6 Citations
  • Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer. (Geethadevi A, Ku Z, Tsaih SW, Parashar D, Kadamberi IP, Xiong W, Deng H, George J, Kumar S, Mittal S, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P) NPJ Precis Oncol 2024 Jun 05;8(1):127 PMID: 38839865 PMCID: PMC11153533 SCOPUS ID: 2-s2.0-85195471255 06/06/2024       1 Citation
  • Multifunctional Nanomaterials: Recent Advancements in Cancer Therapeutics and Vaccines (Gupta S, Kaur R, Bhardwaj A, Parashar D) Indian Journal of Microbiology 2024 SCOPUS ID: 2-s2.0-85194457965 01/01/2024       3 Citations
  • The role of extracellular vesicles in the pathogenesis of gynecological cancer (Chatterjee M, Gupta S, Mukherjee T, Parashar D, Kumar U, Maitra A, Das K) Frontiers in Oncology 2024;14 SCOPUS ID: 2-s2.0-85206369417 01/01/2024    
  • Extracellular Vesicles in Triple-Negative Breast Cancer: Immune Regulation, Biomarkers, and Immunotherapeutic Potential. (Das K, Paul S, Ghosh A, Gupta S, Mukherjee T, Shankar P, Sharma A, Keshava S, Chauhan SC, Kashyap VK, Parashar D) Cancers (Basel) 2023 Oct 07;15(19) PMID: 37835573 PMCID: PMC10571545 SCOPUS ID: 2-s2.0-85173832333 10/14/2023       15 Citations
  • Microbiome based approaches for the degradation of polycyclic aromatic hydrocarbons (PAHs): A current perception. (Kaur R, Gupta S, Tripathi V, Chauhan A, Parashar D, Shankar P, Kashyap V) Chemosphere 2023 Nov;341:139951 PMID: 37652248 SCOPUS ID: 2-s2.0-85170046495 09/01/2023       24 Citations
  • Beyond Macromolecules: Extracellular Vesicles as Regulators of Inflammatory Diseases. (Das K, Paul S, Mukherjee T, Ghosh A, Sharma A, Shankar P, Gupta S, Keshava S, Parashar D) Cells 2023 Jul 29;12(15) PMID: 37566042 PMCID: PMC10417494 SCOPUS ID: 2-s2.0-85167595898 08/11/2023       10 Citations
  • IL6Myc mouse is an immunocompetent model for the development of aggressive multiple myeloma. (Pisano MD, Sun F, Cheng Y, Parashar D, Zhou V, Jing X, Sompallae R, Abrudan J, Zimmermann MT, Mathison A, Janz S, Pufall MA) Haematologica 2023 Dec 01;108(12):3372-3383 PMID: 37439384 PMCID: PMC10690922 SCOPUS ID: 2-s2.0-85178652041 07/13/2023       2 Citations
  • RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2023 Mar 28;42(3):112228 PMID: 36884347 PMCID: PMC10233815 SCOPUS ID: 2-s2.0-85149682952 03/09/2023    
  • CRISPR: the Janus god of modern science (Khare P, Mandal S, Verma AK, Parashar D, Jadhav K, Gupta S) CRISPR-Cas System in Translational Biotechnology 1 January 2023:23-56 SCOPUS ID: 2-s2.0-85183240051 01/01/2023    
  • Stem cell therapy: a novel approach against emerging and re-emerging viral infections with special reference to SARS-CoV-2. (Khandelwal V, Sharma T, Gupta S, Singh S, Sharma MK, Parashar D, Kashyap VK) Mol Biol Rep 2023 Mar;50(3):2663-2683 PMID: 36536185 PMCID: PMC9762873 SCOPUS ID: 2-s2.0-85144283353 12/20/2022       4 Citations
  • CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope (Karn V, Sandhya S, Hsu W, Parashar D, Singh HN, Jha NK, Gupta S, Dubey NK, Kumar S) Cancer Cell International December 2022;22(1) SCOPUS ID: 2-s2.0-85134723611 12/01/2022       37 Citations
  • Emerging Roles and Potential Applications of Non-Coding RNAs in Cervical Cancer. (Parashar D, Singh A, Gupta S, Sharma A, Sharma MK, Roy KK, Chauhan SC, Kashyap VK) Genes (Basel) 2022 Jul 15;13(7) PMID: 35886037 PMCID: PMC9317009 SCOPUS ID: 2-s2.0-85135105098 07/28/2022       15 Citations
  • CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope. (Karn V, Sandhya S, Hsu W, Parashar D, Singh HN, Jha NK, Gupta S, Dubey NK, Kumar S) Cancer Cell Int 2022 Jul 25;22(1):234 PMID: 35879772 PMCID: PMC9316746 SCOPUS ID: 2-s2.0-85134723611 07/26/2022       37 Citations
  • Correction: Parashar et al. Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance. Cancers 2022, 14, 958. (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P) Cancers (Basel) 2022 May 16;14(10) PMID: 35626175 PMCID: PMC9140135 SCOPUS ID: 2-s2.0-85129951244 05/29/2022       2 Citations
  • Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer. (Gupta P, Kadamberi IP, Mittal S, Tsaih SW, George J, Kumar S, Vijayan DK, Geethadevi A, Parashar D, Topchyan P, McAlarnen L, Volkman BF, Cui W, Zhang KYJ, Di Vizio D, Chaluvally-Raghavan P, Pradeep S) Adv Sci (Weinh) 2022 May;9(14):e2104452 PMID: 35289120 PMCID: PMC9108620 SCOPUS ID: 2-s2.0-85126251446 03/16/2022       41 Citations
  • Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance. (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P) Cancers (Basel) 2022 Feb 15;14(4) PMID: 35205706 PMCID: PMC8870411 SCOPUS ID: 2-s2.0-85124460063 02/26/2022       15 Citations
  • RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2021 Nov 02;37(5):109934 PMID: 34731628 PMCID: PMC8675433 SCOPUS ID: 2-s2.0-85118477211 11/04/2021       42 Citations
  • Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. (Geethadevi A, Nair A, Parashar D, Ku Z, Xiong W, Deng H, Li Y, George J, McAllister DM, Sun Y, Kadamberi IP, Gupta P, Dwinell MB, Bradley WH, Rader JS, Rui H, Schwabe RF, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P) Cancer Res 2021 Oct 15;81(20):5336-5352 PMID: 34380633 PMCID: PMC8530981 SCOPUS ID: 2-s2.0-85116424540 08/13/2021       37 Citations
  • Targeted biologic inhibition of both tumor cell-intrinsic and intercellular CLPTM1L/CRR9-mediated chemotherapeutic drug resistance. (Parashar D, Geethadevi A, McAllister D, Ebben J, Peterson FC, Jensen DR, Bishop E, Pradeep S, Volkman BF, Dwinell MB, Chaluvally-Raghavan P, James MA) NPJ Precis Oncol 2021 Mar 02;5(1):16 PMID: 33654182 PMCID: PMC7925570 SCOPUS ID: 2-s2.0-85109651282 03/04/2021       19 Citations
  • Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling. (Parashar D, Nair B, Geethadevi A, George J, Nair A, Tsaih SW, Kadamberi IP, Gopinadhan Nair GK, Lu Y, Ramchandran R, Uyar DS, Rader JS, Ram PT, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cancer Res 2020 Dec 15;80(24):5554-5568 PMID: 33087324 PMCID: PMC7744365 SCOPUS ID: 2-s2.0-85100331032 10/23/2020       31 Citations
  • ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis. (Chen C, Gupta P, Parashar D, Nair GG, George J, Geethadevi A, Wang W, Tsaih SW, Bradley W, Ramchandran R, Rader JS, Chaluvally-Raghavan P, Pradeep S) Oncogene 2020 Apr;39(14):2921-2933 PMID: 32029900 PMCID: PMC7346970 SCOPUS ID: 2-s2.0-85079196544 02/08/2020       33 Citations
  • Cell Cycle Arrest: An Impending Therapeutic Strategy to Curb Cancer (Kumar G, Mittal S, Parashar D, Jadhav K, Geethadevi A, Cheema PS, Tuli HS) Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models 1 January 2020:45-63 SCOPUS ID: 2-s2.0-85153817453 01/01/2020       2 Citations
  • Regulatory Roles of Autophagy in Cancer (Mittal S, Kumar G, Parashar D, Geethadevi A, Jadhav K, Balasubramani GL, Cheema PS, Srivastava CM, Tuli HS) Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models 1 January 2020:89-107 SCOPUS ID: 2-s2.0-85153814818 01/01/2020       3 Citations
  • Metastasis: A Major Driver of Cancer Pathogenesis (Cheema PS, Kumar G, Mittal S, Parashar D, Geethadevi A, Jadhav K, Tuli HS) Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models 1 January 2020:185-211 SCOPUS ID: 2-s2.0-85139600227 01/01/2020       4 Citations
  • miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer. (Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2019 Dec 24;29(13):4389-4406.e10 PMID: 31875548 PMCID: PMC7380555 SCOPUS ID: 2-s2.0-85076674271 12/26/2019       61 Citations
  • Multiplex PCR assay for simultaneous detection and differentiation of Entamoeba histolytica, Giardia lamblia, and Salmonella spp. in the municipality-supplied drinking water. (Shankar P, Mishra J, Bharti V, Parashar D, Singh S) J Lab Physicians 2019;11(3):275-280 PMID: 31579243 PMCID: PMC6771313 10/04/2019    
  • ERBB signaling in CTCs of ovarian cancer and glioblastoma. (Geethadevi A, Parashar D, Bishop E, Pradeep S, Chaluvally-Raghavan P) Genes Cancer 2017 Nov;8(11-12):746-751 PMID: 29321816 PMCID: PMC5755720 SCOPUS ID: 2-s2.0-85042923599 01/13/2018       19 Citations
  • Heat shock protein 70-2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth. (Jagadish N, Parashar D, Gupta N, Agarwal S, Suri V, Kumar R, Suri V, Sadasukhi TC, Gupta A, Ansari AS, Lohiya NK, Suri A) BMC Cancer 2016 Jul 29;16:561 PMID: 27473057 PMCID: PMC4966739 SCOPUS ID: 2-s2.0-84984645680 07/31/2016       52 Citations
  • Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. (Jagadish N, Gupta N, Agarwal S, Parashar D, Sharma A, Fatima R, Topno AP, Kumar V, Suri A) Tumour Biol 2016 Oct;37(10):13101-13110 PMID: 27449044 SCOPUS ID: 2-s2.0-84979207784 07/28/2016       20 Citations
  • A novel cancer testis antigen target A-kinase anchor protein (AKAP4) for the early diagnosis and immunotherapy of colon cancer. (Jagadish N, Parashar D, Gupta N, Agarwal S, Sharma A, Fatima R, Suri V, Kumar R, Gupta A, Lohiya NK, Suri A) Oncoimmunology 2016 Feb;5(2):e1078965 PMID: 27057472 PMCID: PMC4801464 SCOPUS ID: 2-s2.0-84959449907 04/09/2016       24 Citations
  • A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer. (Jagadish N, Parashar D, Gupta N, Agarwal S, Purohit S, Kumar V, Sharma A, Fatima R, Topno AP, Shaha C, Suri A) J Exp Clin Cancer Res 2015 Nov 21;34:142 PMID: 26590805 PMCID: PMC4654903 SCOPUS ID: 2-s2.0-84947926912 11/23/2015       42 Citations
  • Effect of micronutrient supplementation on treatment outcomes in children with intrathoracic tuberculosis: a randomized controlled trial. (Lodha R, Mukherjee A, Singh V, Singh S, Friis H, Faurholt-Jepsen D, Bhatnagar S, Saini S, Kabra SK, Grewal HM, Delhi Pediatric TB Study Group) Am J Clin Nutr 2014 Nov;100(5):1287-97 PMID: 25332327 SCOPUS ID: 2-s2.0-84908129454 10/22/2014       23 Citations
  • Sperm associated antigen 9 plays an important role in bladder transitional cell carcinoma. (Kanojia D, Garg M, Saini S, Agarwal S, Parashar D, Jagadish N, Seth A, Bhatnagar A, Gupta A, Kumar R, Lohiya NK, Suri A) PLoS One 2013;8(12):e81348 PMID: 24349057 PMCID: PMC3857194 SCOPUS ID: 2-s2.0-84892589073 12/19/2013       35 Citations
  • Down regulation of SPAG9 reduces growth and invasive potential of triple-negative breast cancer cells: possible implications in targeted therapy. (Sinha A, Agarwal S, Parashar D, Verma A, Saini S, Jagadish N, Ansari AS, Lohiya NK, Suri A) J Exp Clin Cancer Res 2013 Sep 19;32(1):69 PMID: 24330581 PMCID: PMC3848771 SCOPUS ID: 2-s2.0-84884241535 12/18/2013       42 Citations
  • Role of the QuantiFERON®-TB Gold In-Tube test in the diagnosis of intrathoracic childhood tuberculosis. (Lodha R, Mukherjee A, Saini D, Saini S, Singh V, Singh S, Grewal HM, Kabra SK, Delhi TB Study Group) Int J Tuberc Lung Dis 2013 Nov;17(11):1383-8 PMID: 24125438 SCOPUS ID: 2-s2.0-84888125947 10/16/2013       17 Citations
  • Gene silencing of A-kinase anchor protein 4 inhibits cervical cancer growth in vitro and in vivo. (Saini S, Agarwal S, Sinha A, Verma A, Parashar D, Gupta N, Ansari AS, Lohiya NK, Jagadish N, Suri A) Cancer Gene Ther 2013 Jul;20(7):413-20 PMID: 23764900 SCOPUS ID: 2-s2.0-84880924008 06/15/2013       22 Citations
  • The novel cancer-testis antigen A-kinase anchor protein 4 (AKAP4) is a potential target for immunotherapy of ovarian serous carcinoma. (Agarwal S, Saini S, Parashar D, Verma A, Sinha A, Jagadish N, Batra A, Suri S, Gupta A, Ansari AS, Lohiya NK, Suri A) Oncoimmunology 2013 May 01;2(5):e24270 PMID: 23762804 PMCID: PMC3667910 SCOPUS ID: 2-s2.0-84880916857 06/14/2013       39 Citations
  • Does neutralization of gastric aspirates from children with suspected intrathoracic tuberculosis affect mycobacterial yields on MGIT culture? (Parashar D, Kabra SK, Lodha R, Singh V, Mukherjee A, Arya T, Grewal HM, Singh S, Delhi Pediatric TB Study Group) J Clin Microbiol 2013 Jun;51(6):1753-6 PMID: 23536406 PMCID: PMC3716107 SCOPUS ID: 2-s2.0-84878503405 03/29/2013       20 Citations
  • Expression and humoral response of A-kinase anchor protein 4 in cervical cancer. (Agarwal S, Saini S, Parashar D, Verma A, Jagadish N, Batra A, Suri S, Bhatnagar A, Gupta A, Ansari AS, Lohiya NK, Suri A) Int J Gynecol Cancer 2013 May;23(4):650-8 PMID: 23478221 SCOPUS ID: 2-s2.0-84879893335 03/13/2013       22 Citations
  • Cancer testis antigens: A new paradigm for cancer therapy. (Suri A, Saini S, Sinha A, Agarwal S, Verma A, Parashar D, Singh S, Gupta N, Jagadish N) Oncoimmunology 2012 Oct 01;1(7):1194-1196 PMID: 23170277 PMCID: PMC3494643 SCOPUS ID: 2-s2.0-84872648991 11/22/2012       44 Citations
  • Usefulness of multiplex PCR in the diagnosis of genital tuberculosis in females with infertility. (Sankar MM, Kumar P, Munawwar A, Kumar M, Singh J, Singh A, Parashar D, Malhotra N, Duttagupta S, Singh S) Eur J Clin Microbiol Infect Dis 2013 Mar;32(3):399-405 PMID: 23052988 SCOPUS ID: 2-s2.0-84874114273 10/12/2012       15 Citations
  • Recovery of Mycobacterium tuberculosis from sputum treated with cetyl pyridinium chloride. (Sankar MM, Kumar P, Munawwar A, Singh J, Parashar D, Singh S) J Clin Microbiol 2009 Dec;47(12):4189-90 PMID: 19794041 PMCID: PMC2786653 SCOPUS ID: 2-s2.0-71549158837 10/02/2009       16 Citations
  • Last update: 02/04/2025