Medical College of Wisconsin
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Donghai Xiong PhD

Donghai Xiong PhD profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Pharmacology and Toxicology
Program: Pharmacology

Member of the Center for Disease Prevention Research (CDPR)


Publications (89)

  • Tumor intrinsic immunity related proteins may be novel tumor suppressors in some types of cancer. (Xiong D, Wang Y, You M) Sci Rep 2019 07 29;9(1):10918 PMID: 31358815 PMCID: PMC6662687 SCOPUS ID: 2-s2.0-85069918844 07/31/2019       4 Citations
  • Exosomal miRNAs as Novel Pharmacodynamic Biomarkers for Cancer Chemopreventive Agent Early Stage Treatments in Chemically Induced Mouse Model of Lung Squamous Cell Carcinoma. (Zhou Y, Zhang Q, Du M, Xiong D, Wang Y, Mohammed A, Lubet RA, Wang L, You M) Cancers (Basel) 2019 Apr 04;11(4) PMID: 30987362 PMCID: PMC6520832 04/17/2019    
  • Immunogenomic Landscape Contributes to Hyperprogressive Disease after Anti-PD-1 Immunotherapy for Cancer. (Xiong D, Wang Y, Singavi AK, Mackinnon AC, George B, You M) iScience 2018 Nov 30;9:258-277 PMID: 30439581 PMCID: PMC6234258 11/16/2018    
  • Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity. (Pan J, Lee Y, Cheng G, Zielonka J, Zhang Q, Bajzikova M, Xiong D, Tsaih SW, Hardy M, Flister M, Olsen CM, Wang Y, Vang O, Neuzil J, Myers CR, Kalyanaraman B, You M) iScience 2018 May 25;3:192-207 PMID: 30428319 PMCID: PMC6137433 11/15/2018    
  • Airway brushing as a new experimental methodology to detect airway gene expression signatures in mouse lung squamous cell carcinoma. (Pan J, Xiong D, Zhang Q, Szabo E, Miller MS, Lubet RA, Wang Y, You M) Sci Rep 2018 06 11;8(1):8895 PMID: 29891994 PMCID: PMC5995924 SCOPUS ID: 2-s2.0-85048432720 06/13/2018       1 Citation
  • Novel mutational landscapes and expression signatures of lung squamous cell carcinoma. (Xiong D, Pan J, Yin Y, Jiang H, Szabo E, Lubet RA, Wang Y, You M) Oncotarget 2018 Jan 26;9(7):7424-7441 PMID: 29484121 PMCID: PMC5800913 02/28/2018    
  • Pioglitazone-mediated reversal of elevated glucose metabolism in the airway epithelium of mouse lung adenocarcinomas. (Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, Wang Y, You M) JCI Insight 2017 Jul 06;2(13) PMID: 28679956 PMCID: PMC5499364 SCOPUS ID: 2-s2.0-85062389798 07/07/2017    
  • Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. (Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, You M, Wang Y) Oncotarget 2017 Mar 21;8(12):18885-18900 PMID: 27935865 PMCID: PMC5386655 12/10/2016    
  • Honokiol Decreases Lung Cancer Metastasis through Inhibition of the STAT3 Signaling Pathway. (Pan J, Lee Y, Zhang Q, Xiong D, Wan TC, Wang Y, You M) Cancer Prev Res (Phila) 2017 Feb;10(2):133-141 PMID: 27849557 PMCID: PMC6005650 SCOPUS ID: 2-s2.0-85012027149 11/17/2016       18 Citations
  • Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. (Liu Y, Kheradmand F, Davis CF, Scheurer ME, Wheeler D, Tsavachidis S, Armstrong G, Simpson C, Mandal D, Kupert E, Anderson M, You M, Xiong D, Pikielny C, Schwartz AG, Bailey-Wilson J, Gaba C, De Andrade M, Yang P, Pinney SM, Genetic Epidemiology of Lung Cancer Consortium, Amos CI, Spitz MR) J Thorac Oncol 2016 Jan;11(1):52-61 PMID: 26762739 PMCID: PMC4714038 SCOPUS ID: 2-s2.0-84959355448 01/15/2016       12 Citations
  • PARK2 gene and familial lung cancer: what is the link? (Xiong D, Wang Y, You M) Future Oncol 2015;11(12):1707-10 PMID: 26075437 SCOPUS ID: 2-s2.0-84931479471 06/16/2015       2 Citations
  • Functional characterization of RAD52 as a lung cancer susceptibility gene in the 12p13.33 locus. (Lieberman R, Xiong D, James M, Han Y, Amos CI, Wang L, You M) Mol Carcinog 2016 May;55(5):953-63 PMID: 26013599 PMCID: PMC4662629 SCOPUS ID: 2-s2.0-84930260740 05/28/2015       21 Citations
  • SPARCoC: a new framework for molecular pattern discovery and cancer gene identification. (Ma S, Johnson D, Ashby C, Xiong D, Cramer CL, Moore JH, Zhang S, Huang X) PLoS One 2015;10(3):e0117135 PMID: 25768286 PMCID: PMC4359112 SCOPUS ID: 2-s2.0-84928914706 03/15/2015       6 Citations
  • Big data - a 21st century science Maginot Line? No-boundary thinking: shifting from the big data paradigm. (Huang X, Jennings SF, Bruce B, Buchan A, Cai L, Chen P, Cramer CL, Guan W, Hilgert UK, Jiang H, Li Z, McClure G, McMullen DF, Nanduri B, Perkins A, Rekepalli B, Salem S, Specker J, Walker K, Wunsch D, Xiong D, Zhang S, Zhang Y, Zhao Z, Moore JH) BioData Min 2015;8:7 PMID: 25670967 PMCID: PMC4323225 02/12/2015    
  • A recurrent mutation in PARK2 is associated with familial lung cancer. (Xiong D, Wang Y, Kupert E, Simpson C, Pinney SM, Gaba CR, Mandal D, Schwartz AG, Yang P, de Andrade M, Pikielny C, Byun J, Li Y, Stambolian D, Spitz MR, Liu Y, Amos CI, Bailey-Wilson JE, Anderson M, You M) Am J Hum Genet 2015 Feb 05;96(2):301-8 PMID: 25640678 PMCID: PMC4320264 SCOPUS ID: 2-s2.0-84925106543 02/03/2015       36 Citations
  • Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer. (Morrison CD, Liu P, Woloszynska-Read A, Zhang J, Luo W, Qin M, Bshara W, Conroy JM, Sabatini L, Vedell P, Xiong D, Liu S, Wang J, Shen H, Li Y, Omilian AR, Hill A, Head K, Guru K, Kunnev D, Leach R, Eng KH, Darlak C, Hoeflich C, Veeranki S, Glenn S, You M, Pruitt SC, Johnson CS, Trump DL) Proc Natl Acad Sci U S A 2014 Feb 11;111(6):E672-81 PMID: 24469795 PMCID: PMC3926024 SCOPUS ID: 2-s2.0-84893848638 01/29/2014       62 Citations
  • Transcriptomic analysis by RNA-seq reveals AP-1 pathway as key regulator that green tea may rely on to inhibit lung tumorigenesis. (Pan J, Zhang Q, Xiong D, Vedell P, Yan Y, Jiang H, Cui P, Ding F, Tichelaar JW, Wang Y, Lubet RA, You M) Mol Carcinog 2014 Jan;53(1):19-29 PMID: 24343902 12/18/2013    
  • No-boundary thinking in bioinformatics research. (Huang X, Bruce B, Buchan A, Congdon CB, Cramer CL, Jennings SF, Jiang H, Li Z, McClure G, McMullen R, Moore JH, Nanduri B, Peckham J, Perkins A, Polson SW, Rekepalli B, Salem S, Specker J, Wunsch D, Xiong D, Zhang S, Zhao Z) BioData Min 2013 Nov 06;6(1):19 PMID: 24192339 PMCID: PMC3827872 11/07/2013    
  • Driver genes as targets for lung cancer prevention and treatment (Xiong D, Osarogiagbon RU, Wang Y, You M) Progress in Chemistry September 2013;25(9):1517-1525 SCOPUS ID: 2-s2.0-84885357707 09/01/2013    
  • Genomic landscape of non-small cell lung cancer in smokers and never-smokers. (Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, Maher CA, Fulton R, Fulton L, Wallis J, Chen K, Walker J, McDonald S, Bose R, Ornitz D, Xiong D, You M, Dooling DJ, Watson M, Mardis ER, Wilson RK) Cell 2012 Sep 14;150(6):1121-34 PMID: 22980976 PMCID: PMC3656590 SCOPUS ID: 2-s2.0-84866434919 09/18/2012       744 Citations
  • Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients. (Xiong D, Li G, Li K, Xu Q, Pan Z, Ding F, Vedell P, Liu P, Cui P, Hua X, Jiang H, Yin Y, Zhu Z, Li X, Zhang B, Ma D, Wang Y, You M) Carcinogenesis 2012 Sep;33(9):1797-805 PMID: 22696596 PMCID: PMC3514907 SCOPUS ID: 2-s2.0-84865569656 06/15/2012       35 Citations
  • ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. (Chen XD, Xiong DH, Yang TL, Pei YF, Guo YF, Li J, Yang F, Pan F, Tan LJ, Yan H, Liu XG, Lei SF, Li X, Ning LL, Zhu XZ, Levy S, Kranzler HR, Farrer LA, Gelernter J, Recker RR, Deng HW) Chin Med J (Engl) 2012 Mar;125(6):1127-34 PMID: 22613542 PMCID: PMC4174677 SCOPUS ID: 2-s2.0-84862243335 05/23/2012       14 Citations
  • Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. (Liu P, Morrison C, Wang L, Xiong D, Vedell P, Cui P, Hua X, Ding F, Lu Y, James M, Ebben JD, Xu H, Adjei AA, Head K, Andrae JW, Tschannen MR, Jacob H, Pan J, Zhang Q, Van den Bergh F, Xiao H, Lo KC, Patel J, Richmond T, Watt MA, Albert T, Selzer R, Anderson M, Wang J, Wang Y, Starnes S, Yang P, You M) Carcinogenesis 2012 Jul;33(7):1270-6 PMID: 22510280 PMCID: PMC3499051 SCOPUS ID: 2-s2.0-84865168855 04/19/2012       130 Citations
  • Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. (Zhang L, Guo YF, Liu YZ, Liu YJ, Xiong DH, Liu XG, Wang L, Yang TL, Lei SF, Guo Y, Yan H, Pei YF, Zhang F, Papasian CJ, Recker RR, Deng HW) J Bone Miner Res 2010 Jul;25(7):1572-80 PMID: 20200951 PMCID: PMC3153999 SCOPUS ID: 2-s2.0-77954701060 03/05/2010       66 Citations
  • Genome-wide association study for femoral neck bone geometry. (Zhao LJ, Liu XG, Liu YZ, Liu YJ, Papasian CJ, Sha BY, Pan F, Guo YF, Wang L, Yan H, Xiong DH, Tang ZH, Yang TL, Chen XD, Guo Y, Li J, Shen H, Zhang F, Lei SF, Recker RR, Deng HW) J Bone Miner Res 2010 Feb;25(2):320-9 PMID: 20175129 PMCID: PMC3153387 SCOPUS ID: 2-s2.0-77953419885 02/23/2010       28 Citations
  • IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study. (Guo Y, Zhang LS, Yang TL, Tian Q, Xiong DH, Pei YF, Deng HW) J Bone Miner Res 2010 May;25(5):1042-8 PMID: 19874204 PMCID: PMC3153368 SCOPUS ID: 2-s2.0-77953523922 10/31/2009       26 Citations
  • Pathway-based genome-wide association analysis identified the importance of EphrinA-EphR pathway for femoral neck bone geometry. (Chen Y, Xiong DH, Guo YF, Pan F, Zhou Q, Zhang F, Deng HW) Bone 2010 Jan;46(1):129-36 PMID: 19786129 PMCID: PMC2818219 SCOPUS ID: 2-s2.0-72149108138 09/30/2009       19 Citations
  • Association analyses of vitamin D-binding protein gene with compression strength index variation in Caucasian nuclear families. (Xu XH, Xiong DH, Liu XG, Guo Y, Chen Y, Zhao J, Recker RR, Deng HW) Osteoporos Int 2010 Jan;21(1):99-107 PMID: 19543766 PMCID: PMC2914268 SCOPUS ID: 2-s2.0-72449125162 06/23/2009       15 Citations
  • Association analyses of RANKL/RANK/OPG gene polymorphisms with femoral neck compression strength index variation in Caucasians. (Dong SS, Liu XG, Chen Y, Guo Y, Wang L, Zhao J, Xiong DH, Xu XH, Recker RR, Deng HW) Calcif Tissue Int 2009 Aug;85(2):104-12 PMID: 19458885 PMCID: PMC2916082 SCOPUS ID: 2-s2.0-69249215226 05/22/2009       38 Citations
  • Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche. (Liu YZ, Guo YF, Wang L, Tan LJ, Liu XG, Pei YF, Yan H, Xiong DH, Deng FY, Yu N, Zhang YP, Zhang L, Lei SF, Chen XD, Liu HB, Zhu XZ, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Deng HW) PLoS Genet 2009 Mar;5(3):e1000420 PMID: 19282985 PMCID: PMC2652107 SCOPUS ID: 2-s2.0-63449113425 03/14/2009       52 Citations
  • Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. (Liu XG, Tan LJ, Lei SF, Liu YJ, Shen H, Wang L, Yan H, Guo YF, Xiong DH, Chen XD, Pan F, Yang TL, Zhang YP, Guo Y, Tang NL, Zhu XZ, Deng HY, Levy S, Recker RR, Papasian CJ, Deng HW) Am J Hum Genet 2009 Mar;84(3):418-23 PMID: 19268274 PMCID: PMC2668008 SCOPUS ID: 2-s2.0-61849137254 03/10/2009       73 Citations
  • Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. (Xiong DH, Liu XG, Guo YF, Tan LJ, Wang L, Sha BY, Tang ZH, Pan F, Yang TL, Chen XD, Lei SF, Yerges LM, Zhu XZ, Wheeler VW, Patrick AL, Bunker CH, Guo Y, Yan H, Pei YF, Zhang YP, Levy S, Papasian CJ, Xiao P, Lundberg YW, Recker RR, Liu YZ, Liu YJ, Zmuda JM, Deng HW) Am J Hum Genet 2009 Mar;84(3):388-98 PMID: 19249006 PMCID: PMC2667986 SCOPUS ID: 2-s2.0-61849164536 03/03/2009       139 Citations
  • Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15. (Liu YZ, Pei YF, Guo YF, Wang L, Liu XG, Yan H, Xiong DH, Zhang YP, Levy S, Li J, Haddock CK, Papasian CJ, Xu Q, Ma JZ, Payne TJ, Recker RR, Li MD, Deng HW) Mol Psychiatry 2009 Jul;14(7):668-80 PMID: 19188921 PMCID: PMC2700850 SCOPUS ID: 2-s2.0-67649319205 02/04/2009       37 Citations
  • Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation. (Lei SF, Tan LJ, Liu XG, Wang L, Yan H, Guo YF, Liu YZ, Xiong DH, Li J, Yang TL, Chen XD, Guo Y, Deng FY, Zhang YP, Zhu XZ, Levy S, Papasian CJ, Hamilton JJ, Recker RR, Deng HW) Hum Mol Genet 2009 May 01;18(9):1661-9 PMID: 19039035 PMCID: PMC2667283 SCOPUS ID: 2-s2.0-64549090614 11/29/2008       25 Citations
  • Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. (Liu YZ, Wilson SG, Wang L, Liu XG, Guo YF, Li J, Yan H, Deloukas P, Soranzo N, Chinappen-Horsley U, Cervino A, Williams FM, Xiong DH, Zhang YP, Jin TB, Levy S, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Spector TD, Deng HW) PLoS One 2008 Sep 08;3(9):e3160 PMID: 18776929 PMCID: PMC2522269 SCOPUS ID: 2-s2.0-52349086806 09/09/2008       45 Citations
  • Polymorphisms of the tumor necrosis factor-alpha receptor 2 gene are associated with obesity phenotypes among 405 Caucasian nuclear families. (Zhao LJ, Xiong DH, Pan F, Liu XG, Recker RR, Deng HW) Hum Genet 2008 Sep;124(2):171-7 PMID: 18685868 PMCID: PMC4176887 SCOPUS ID: 2-s2.0-50649083462 08/08/2008       3 Citations
  • A bivariate whole genome linkage study identified genomic regions influencing both BMD and bone structure. (Liu XG, Liu YJ, Liu J, Pei Y, Xiong DH, Shen H, Deng HY, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Deng HW) J Bone Miner Res 2008 Nov;23(11):1806-14 PMID: 18597637 PMCID: PMC2685488 SCOPUS ID: 2-s2.0-54349097569 07/04/2008       11 Citations
  • Comprehensive association analyses of IGF1, ESR2, and CYP17 genes with adult height in Caucasians. (Yang TL, Xiong DH, Guo Y, Recker RR, Deng HW) Eur J Hum Genet 2008 Nov;16(11):1380-7 PMID: 18560445 SCOPUS ID: 2-s2.0-54549088818 06/19/2008       11 Citations
  • Genetic determination of osteoporosis: lessons learned from a large genome-wide linkage study. (Xiong DH, Wang JT, Wang W, Guo YF, Xiao P, Shen H, Jiang H, Chen Y, Deng H, Drees B, Recker RR, Deng HW) Hum Biol 2007 Dec;79(6):593-608 PMID: 18494371 SCOPUS ID: 2-s2.0-42649138199 05/23/2008       6 Citations
  • Quantitative trait loci mapping. (Xiong DH, Liu JF, Guo YF, Guo Y, Yang TL, Jiang H, Chen Y, Yang F, Recker RR, Deng HW) Methods Mol Biol 2008;455:203-35 PMID: 18463822 SCOPUS ID: 2-s2.0-84934441488 05/09/2008       2 Citations
  • Association study of the oestrogen signalling pathway genes in relation to age at natural menopause. (He LN, Xiong DH, Liu YJ, Zhang F, Recker RR, Deng HW) J Genet 2007 Dec;86(3):269-76 PMID: 18305346 SCOPUS ID: 2-s2.0-40549098079 02/29/2008       22 Citations
  • The MTHFR gene polymorphism is associated with lean body mass but not fat body mass. (Liu X, Zhao LJ, Liu YJ, Xiong DH, Recker RR, Deng HW) Hum Genet 2008 Mar;123(2):189-96 PMID: 18180959 SCOPUS ID: 2-s2.0-39549101242 01/09/2008       21 Citations
  • Sex-specific association of the glucocorticoid receptor gene with extreme BMD. (Peng YM, Lei SF, Guo Y, Xiong DH, Yan H, Wang L, Guo YF, Deng HW) J Bone Miner Res 2008 Feb;23(2):247-52 PMID: 17937535 PMCID: PMC2665695 SCOPUS ID: 2-s2.0-38549092629 10/17/2007       12 Citations
  • A whole genome linkage scan for QTLs underlying peak bone mineral density. (Zhang F, Xiao P, Yang F, Shen H, Xiong DH, Deng HY, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Deng HW) Osteoporos Int 2008 Mar;19(3):303-10 PMID: 17882466 SCOPUS ID: 2-s2.0-38849207606 09/21/2007       11 Citations
  • Variations in RANK gene are associated with adult height in Caucasians. (Chen Y, Xiong DH, Yang TL, Yang F, Jiang H, Zhang F, Shen H, Xiao P, Recker RR, Deng HW) Am J Hum Biol 2007 Jul-Aug;19(4):559-65 PMID: 17546619 SCOPUS ID: 2-s2.0-34447309720 06/05/2007       6 Citations
  • A bivariate whole-genome linkage scan suggests several shared genomic regions for obesity and osteoporosis. (Tang ZH, Xiao P, Lei SF, Deng FY, Zhao LJ, Deng HY, Tan LJ, Shen H, Xiong DH, Recker RR, Deng HW) J Clin Endocrinol Metab 2007 Jul;92(7):2751-7 PMID: 17473065 SCOPUS ID: 2-s2.0-34447119565 05/03/2007       40 Citations
  • Genetic determination in onset age of wrist fracture. (Xiong D, Wang W, Chen Y, Jiang H, Deng HW) J Hum Genet 2007;52(6):481-484 PMID: 17457512 SCOPUS ID: 2-s2.0-34249731077 04/26/2007       1 Citation
  • Polymorphism in the insulin-like growth factor 1 gene is associated with age at menarche in caucasian females. (Zhao J, Xiong DH, Guo Y, Yang TL, Recker RR, Deng HW) Hum Reprod 2007 Jun;22(6):1789-94 PMID: 17376820 SCOPUS ID: 2-s2.0-34447308215 03/23/2007       33 Citations
  • Association analysis of vitamin D-binding protein gene polymorphisms with variations of obesity-related traits in Caucasian nuclear families. (Jiang H, Xiong DH, Guo YF, Shen H, Xiao P, Yang F, Chen Y, Zhang F, Recker RR, Deng HW) Int J Obes (Lond) 2007 Aug;31(8):1319-24 PMID: 17342072 SCOPUS ID: 2-s2.0-34547431046 03/08/2007       26 Citations
  • Epistatic interactions between genomic regions containing the COL1A1 gene and genes regulating osteoclast differentiation may influence femoral neck bone mineral density. (Yang TL, Shen H, Xiong DH, Xiao P, Guo Y, Guo YF, Liu YZ, Recker RR, Deng HW) Ann Hum Genet 2007 Mar;71(Pt 2):152-9 PMID: 17331078 SCOPUS ID: 2-s2.0-34047275241 03/03/2007       4 Citations
  • Low-density lipoprotein receptor-related protein 5 (LRP5) gene polymorphisms are associated with bone mass in both Chinese and whites. (Xiong DH, Lei SF, Yang F, Wang L, Peng YM, Wang W, Recker RR, Deng HW) J Bone Miner Res 2007 Mar;22(3):385-93 PMID: 17241106 SCOPUS ID: 2-s2.0-34247258995 01/24/2007       35 Citations
  • Recent progress in the genetics of osteoporosis (Shen H, Liu YJ, Xiao P, Xiong DH, Deng HW) Current Topics in Human Genetics: Studies in Complex Diseases 1 January 2007:617-630 SCOPUS ID: 2-s2.0-84967444129 01/01/2007    
  • The chemokine (C-C-motif) receptor 3 (CCR3) gene is linked and associated with age at menarche in Caucasian females. (Yang F, Xiong DH, Guo Y, Shen H, Xiao P, Zhang F, Jiang H, Recker RR, Deng HW) Hum Genet 2007 Mar;121(1):35-42 PMID: 17146638 PMCID: PMC1829487 SCOPUS ID: 2-s2.0-33947208893 12/06/2006       14 Citations
  • Pharmacogenomic approaches to osteoporosis: 2005 update (Chen Y, Xiong DH, Jiang H, Deng HW) Current Pharmacogenomics December 2006;4(4):271-276 SCOPUS ID: 2-s2.0-33845380867 12/01/2006    
  • A genome-wide linkage scan for quantitative trait loci underlying obesity related phenotypes in 434 Caucasian families. (Zhao LJ, Xiao P, Liu YJ, Xiong DH, Shen H, Recker RR, Deng HW) Hum Genet 2007 Mar;121(1):145-8 PMID: 17115187 SCOPUS ID: 2-s2.0-33947245930 11/23/2006       17 Citations
  • Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction. (Xiong DH, Shen H, Zhao LJ, Xiao P, Yang TL, Guo Y, Wang W, Guo YF, Liu YJ, Recker RR, Deng HW) J Bone Miner Res 2006 Nov;21(11):1678-95 PMID: 17002564 PMCID: PMC1829486 SCOPUS ID: 2-s2.0-33750568298 09/28/2006       80 Citations
  • Genomic regions identified for BMD in a large sample including epistatic interactions and gender-specific effects. (Xiao P, Shen H, Guo YF, Xiong DH, Liu YZ, Liu YJ, Zhao LJ, Long JR, Guo Y, Recker RR, Deng HW) J Bone Miner Res 2006 Oct;21(10):1536-44 PMID: 16995807 SCOPUS ID: 2-s2.0-33749247815 09/26/2006       51 Citations
  • Molecular genetic studies of gene identification for osteoporosis: a 2004 update. (Liu YJ, Shen H, Xiao P, Xiong DH, Li LH, Recker RR, Deng HW) J Bone Miner Res 2006 Oct;21(10):1511-35 PMID: 16995806 PMCID: PMC1829484 SCOPUS ID: 2-s2.0-33745612144 09/26/2006       101 Citations
  • Is a gene important for bone resorption a candidate for obesity? An association and linkage study on the RANK (receptor activator of nuclear factor-kappaB) gene in a large Caucasian sample. (Zhao LJ, Guo YF, Xiong DH, Xiao P, Recker RR, Deng HW) Hum Genet 2006 Nov;120(4):561-70 PMID: 16960694 PMCID: PMC1829481 SCOPUS ID: 2-s2.0-33750552739 09/09/2006       15 Citations
  • HDC gene polymorphisms are associated with age at natural menopause in Caucasian women. (Zhang F, Xiong DH, Wang W, Shen H, Xiao P, Yang F, Recker RR, Deng HW) Biochem Biophys Res Commun 2006 Oct 06;348(4):1378-82 PMID: 16919600 PMCID: PMC1803761 SCOPUS ID: 2-s2.0-33748136965 08/22/2006       16 Citations
  • Epistasis between loci on chromosomes 2 and 6 influences human height. (Liu YZ, Guo YF, Xiao P, Xiong DH, Zhao LJ, Shen H, Liu YJ, Dvornyk V, Long JR, Deng HY, Li JL, Deng HW) J Clin Endocrinol Metab 2006 Oct;91(10):3821-5 PMID: 16849413 SCOPUS ID: 2-s2.0-33749567371 07/20/2006       5 Citations
  • Assessment of genetic linkage and parent-of-origin effects on obesity. (Guo YF, Shen H, Liu YJ, Wang W, Xiong DH, Xiao P, Liu YZ, Zhao LJ, Recker RR, Deng HW) J Clin Endocrinol Metab 2006 Oct;91(10):4001-5 PMID: 16835282 SCOPUS ID: 2-s2.0-33749567351 07/13/2006       28 Citations
  • A genomewide scan for quantitative trait loci underlying areal bone size variation in 451 Caucasian families. (Shen H, Long JR, Xiong DH, Guo YF, Xiao P, Liu YZ, Zhao LJ, Liu YJ, Deng HY, Li JL, Recker RR, Deng HW) J Med Genet 2006 Nov;43(11):873-80 PMID: 16825438 PMCID: PMC2563191 SCOPUS ID: 2-s2.0-33751207722 07/11/2006       9 Citations
  • Polymorphisms of estrogen-biosynthesis genes CYP17 and CYP19 may influence age at menarche: a genetic association study in Caucasian females. (Guo Y, Xiong DH, Yang TL, Guo YF, Recker RR, Deng HW) Hum Mol Genet 2006 Aug 15;15(16):2401-8 PMID: 16782804 PMCID: PMC1803760 SCOPUS ID: 2-s2.0-33747875890 06/20/2006       37 Citations
  • Association analyses of CYP19 gene polymorphisms with height variation in a large sample of Caucasian nuclear families. (Yang TL, Xiong DH, Guo Y, Recker RR, Deng HW) Hum Genet 2006 Aug;120(1):119-25 PMID: 16733710 PMCID: PMC1829483 SCOPUS ID: 2-s2.0-33745686135 05/31/2006       11 Citations
  • Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study. (Guo YF, Xiong DH, Shen H, Zhao LJ, Xiao P, Guo Y, Wang W, Yang TL, Recker RR, Deng HW) J Med Genet 2006 Oct;43(10):798-803 PMID: 16723389 PMCID: PMC1829485 SCOPUS ID: 2-s2.0-33750458964 05/26/2006       83 Citations
  • Ethnic difference in osteoporosis-related phenotypes and its potential underlying genetic determination. (Lei SF, Chen Y, Xiong DH, Li LM, Deng HW) J Musculoskelet Neuronal Interact 2006 Jan-Mar;6(1):36-46 PMID: 16675888 SCOPUS ID: 2-s2.0-33646686195 05/06/2006       42 Citations
  • Genome-wide scan identified QTLs underlying femoral neck cross-sectional geometry that are novel studied risk factors of osteoporosis. (Xiong DH, Shen H, Xiao P, Guo YF, Long JR, Zhao LJ, Liu YZ, Deng HY, Li JL, Recker RR, Deng HW) J Bone Miner Res 2006 Mar;21(3):424-37 PMID: 16491291 SCOPUS ID: 2-s2.0-33644541419 02/24/2006       37 Citations
  • Genetic linkage of human height is confirmed to 9q22 and Xq24. (Liu YZ, Xiao P, Guo YF, Xiong DH, Zhao LJ, Shen H, Liu YJ, Dvornyk V, Long JR, Deng HY, Li JL, Recker RR, Deng HW) Hum Genet 2006 Apr;119(3):295-304 PMID: 16446976 SCOPUS ID: 2-s2.0-33644998501 02/01/2006       25 Citations
  • Genomewide linkage scan for quantitative trait loci underlying variation in age at menarche. (Guo Y, Shen H, Xiao P, Xiong DH, Yang TL, Guo YF, Long JR, Recker RR, Deng HW) J Clin Endocrinol Metab 2006 Mar;91(3):1009-14 PMID: 16394082 SCOPUS ID: 2-s2.0-33644830650 01/06/2006       45 Citations
  • Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families. (Xiong DH, Liu YZ, Liu PY, Zhao LJ, Deng HW) Osteoporos Int 2005 Dec;16(12):2113-22 PMID: 16292600 SCOPUS ID: 2-s2.0-29044431732 11/18/2005       23 Citations
  • Mapping quantitative trait loci for cross-sectional geometry at the femoral neck. (Shen H, Long JR, Xiong DH, Liu YJ, Liu YZ, Xiao P, Zhao LJ, Dvornyk V, Zhang YY, Rocha-Sanchez S, Liu PY, Li JL, Deng HW) J Bone Miner Res 2005 Nov;20(11):1973-82 PMID: 16234971 SCOPUS ID: 2-s2.0-27444437567 10/20/2005       24 Citations
  • The oestrogen receptor alpha gene is linked and/or associated with age of menarche in different ethnic groups. (Long JR, Xu H, Zhao LJ, Liu PY, Shen H, Liu YJ, Xiong DH, Xiao P, Liu YZ, Dvornyk V, Li JL, Recker RR, Deng HW) J Med Genet 2005 Oct;42(10):796-800 PMID: 16199553 PMCID: PMC1735934 SCOPUS ID: 2-s2.0-26944450070 10/04/2005       36 Citations
  • Searching for obesity genes: progress and prospects. (Liu YJ, Xiao P, Xiong DH, Recker RR, Deng HW) Drugs Today (Barc) 2005 May;41(5):345-62 PMID: 16082432 SCOPUS ID: 2-s2.0-23044456626 08/06/2005       8 Citations
  • Association tests of interleukin-6 (IL-6) and type II tumor necrosis factor receptor (TNFR2) genes with bone mineral density in Caucasians using a re-sampling approach. (Xiao P, Liu PY, Lu Y, Guo YF, Xiong DH, Li LH, Recker RR, Deng HW) Hum Genet 2005 Aug;117(4):340-8 PMID: 15906094 SCOPUS ID: 2-s2.0-23944450368 05/21/2005       9 Citations
  • The genetics of osteoporosis. (Long JR, Xiong DH, Recker RR, Deng HW) Drugs Today (Barc) 2005 Mar;41(3):205-18 PMID: 15883617 SCOPUS ID: 2-s2.0-18244392689 05/11/2005       3 Citations
  • Vitamin D receptor gene polymorphisms are linked to and associated with adult height. (Xiong DH, Xu FH, Liu PY, Shen H, Long JR, Elze L, Recker RR, Deng HW) J Med Genet 2005 Mar;42(3):228-34 PMID: 15744036 PMCID: PMC1736013 SCOPUS ID: 2-s2.0-15044357372 03/04/2005       49 Citations
  • A survey of haplotype variants at several disease candidate genes: the importance of rare variants for complex diseases. (Liu PY, Zhang YY, Lu Y, Long JR, Shen H, Zhao LJ, Xu FH, Xiao P, Xiong DH, Liu YJ, Recker RR, Deng HW) J Med Genet 2005 Mar;42(3):221-7 PMID: 15744035 PMCID: PMC1736011 SCOPUS ID: 2-s2.0-20144371261 03/04/2005       41 Citations
  • Association between VDR ApaI polymorphism and hip bone mineral density can be modified by body mass index: a study on postmenopausal Chinese women. (Xu H, Xiong DH, Xu FH, Zhang YY, Lei SF, Deng HW) Acta Biochim Biophys Sin (Shanghai) 2005 Jan;37(1):61-7 PMID: 15645083 SCOPUS ID: 2-s2.0-18644370056 01/13/2005       18 Citations
  • Pharmacogenetics and pharmacogenomics of osteoporosis (Xiong DH, Long JR, Xiao S, Deng HW) Current Topics in Osteoporosis 1 January 2005:445-465 SCOPUS ID: 2-s2.0-84967588244 01/01/2005    
  • APOE haplotypes influence bone mineral density in Caucasian males but not females. (Long JR, Liu PY, Liu YJ, Lu Y, Shen H, Zhao LJ, Xiong DH, Deng HW) Calcif Tissue Int 2004 Oct;75(4):299-304 PMID: 15549644 SCOPUS ID: 2-s2.0-11244262704 11/19/2004       19 Citations
  • Genetic dissection of human stature in a large sample of multiplex pedigrees. (Liu YZ, Xu FH, Shen H, Liu YJ, Zhao LJ, Long JR, Zhang YY, Xiao P, Xiong DH, Dvornyk V, Li JL, Conway T, Davies KM, Recker RR, Deng HW) Ann Hum Genet 2004 Sep;68(Pt 5):472-88 PMID: 15469424 SCOPUS ID: 2-s2.0-6444239276 10/08/2004       30 Citations
  • A genome-wide linkage scan for bone mineral density in an extended sample: evidence for linkage on 11q23 and Xq27. (Shen H, Zhang YY, Long JR, Xu FH, Liu YZ, Xiao P, Zhao LJ, Xiong DH, Liu YJ, Dvornyk V, Rocha-Sanchez S, Liu PY, Li JL, Conway T, Davies KM, Recker RR, Deng HW) J Med Genet 2004 Oct;41(10):743-51 PMID: 15466007 PMCID: PMC1735607 SCOPUS ID: 2-s2.0-6344265517 10/07/2004       50 Citations
  • Tests of linkage and/or association of TGF-beta1 and COL1A1 genes with bone mass. (Long JR, Liu PY, Lu Y, Dvornyk V, Xiong DH, Zhao LJ, Deng HW) Osteoporos Int 2005 Jan;16(1):86-92 PMID: 15164160 SCOPUS ID: 2-s2.0-13244255482 05/28/2004       14 Citations
  • Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes. (Long JR, Zhao LJ, Liu PY, Lu Y, Dvornyk V, Shen H, Liu YJ, Zhang YY, Xiong DH, Xiao P, Deng HW) BMC Genet 2004 May 24;5:11 PMID: 15157284 PMCID: PMC421754 SCOPUS ID: 2-s2.0-25444510847 05/26/2004       29 Citations
  • Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis. (Dvornyk V, Long JR, Xiong DH, Liu PY, Zhao LJ, Shen H, Zhang YY, Liu YJ, Rocha-Sanchez S, Xiao P, Recker RR, Deng HW) BMC Genet 2004 Feb 25;5:4 PMID: 15113403 PMCID: PMC395827 SCOPUS ID: 2-s2.0-2442684156 04/29/2004       32 Citations
  • Association between COL1A1 gene polymorphisms and bone size in Caucasians. (Long JR, Liu PY, Lu Y, Xiong DH, Zhao LJ, Zhang YY, Elze L, Recker RR, Deng HW) Eur J Hum Genet 2004 May;12(5):383-8 PMID: 14722584 SCOPUS ID: 2-s2.0-2442672867 01/15/2004       19 Citations
  • APOE and TGF-beta1 genes are associated with obesity phenotypes. (Long JR, Liu PY, Liu YJ, Lu Y, Xiong DH, Elze L, Recker RR, Deng HW) J Med Genet 2003 Dec;40(12):918-24 PMID: 14684691 PMCID: PMC1735335 SCOPUS ID: 2-s2.0-1542437966 12/20/2003       35 Citations
  • Pharmacogenomic approaches to osteoporosis. (Xiong DH, Long JR, Recker RR, Deng HW) Pharmacogenomics J 2003;3(5):261-3 PMID: 14583795 SCOPUS ID: 2-s2.0-0242407565 10/30/2003       6 Citations
  • Last update: 09/29/2019
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