Medical College of Wisconsin
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Donna K. Mahnke

Research Scientist I

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Cardiology

Publications (17)

  • Total Cell-Free DNA Predicts Death and Infection Following Pediatric and Adult Heart Transplantation. (Scott JP, Ragalie WS, Stamm KD, Mahnke DK, Liang HL, Simpson PM, Dasgupta M, Katz R, North PE, Tomita-Mitchell A, Zangwill SD, Kindel SJ, Mitchell ME) Ann Thorac Surg 2021 Oct;112(4):1282-1289 PMID: 33039362 SCOPUS ID: 2-s2.0-85103701202 10/12/2020       8 Citations
  • Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction. (Samudrala SSK, North LM, Stamm KD, Earing MG, Frommelt MA, Willes R, Tripathi S, Dsouza NR, Zimmermann MT, Mahnke DK, Liang HL, Lund M, Lin CW, Geddes GC, Mitchell ME, Tomita-Mitchell A) Mol Genet Genomic Med 2020 Apr;8(4):e1152 PMID: 31985165 PMCID: PMC7196453 SCOPUS ID: 2-s2.0-85078673520 01/28/2020       9 Citations
  • Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability. (North PE, Ziegler E, Mahnke DK, Stamm KD, Thomm A, Daft P, Goetsch M, Liang HL, Baker MA, Vepraskas A, Rosenau C, Dasgupta M, Simpson P, Mitchell ME, Tomita-Mitchell A) PLoS One 2020;15(1):e0227385 PMID: 31929557 PMCID: PMC6957190 SCOPUS ID: 2-s2.0-85077765307 01/14/2020       23 Citations
  • Human genotyping and an experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta. (LaDisa JF Jr, Tomita-Mitchell A, Stamm K, Bazan K, Mahnke DK, Goetsch MA, Wegter BJ, Gerringer JW, Repp K, Palygin O, Zietara AP, Krolikowski MM, Eddinger TJ, Alli AA, Mitchell ME) Physiol Genomics 2019 Jun 01;51(6):177-185 PMID: 31002586 PMCID: PMC6620646 SCOPUS ID: 2-s2.0-85066457176 04/20/2019       12 Citations
  • Impact of MYH6 variants in hypoplastic left heart syndrome. (Tomita-Mitchell A, Stamm KD, Mahnke DK, Kim MS, Hidestrand PM, Liang HL, Goetsch MA, Hidestrand M, Simpson P, Pelech AN, Tweddell JS, Benson DW, Lough JW, Mitchell ME) Physiol Genomics 2016 Dec 01;48(12):912-921 PMID: 27789736 PMCID: PMC5206387 SCOPUS ID: 2-s2.0-85006309110 10/30/2016       55 Citations
  • Effect of 22q11.2 deletion on bleeding and transfusion utilization in children with congenital heart disease undergoing cardiac surgery. (Brenner MK, Clarke S, Mahnke DK, Simpson P, Bercovitz RS, Tomita-Mitchell A, Mitchell ME, Newman DK) Pediatr Res 2016 Feb;79(2):318-24 PMID: 26492284 PMCID: PMC5114022 SCOPUS ID: 2-s2.0-84982285447 10/23/2015       23 Citations
  • Human gene copy number spectra analysis in congenital heart malformations. (Tomita-Mitchell A, Mahnke DK, Struble CA, Tuffnell ME, Stamm KD, Hidestrand M, Harris SE, Goetsch MA, Simpson PM, Bick DP, Broeckel U, Pelech AN, Tweddell JS, Mitchell ME) Physiol Genomics 2012 May 01;44(9):518-41 PMID: 22318994 PMCID: PMC3426426 SCOPUS ID: 2-s2.0-84862128193 02/10/2012       80 Citations
  • Multiplexed quantitative real-time PCR to detect 22q11.2 deletion in patients with congenital heart disease. (Tomita-Mitchell A, Mahnke DK, Larson JM, Ghanta S, Feng Y, Simpson PM, Broeckel U, Duffy K, Tweddell JS, Grossman WJ, Routes JM, Mitchell ME) Physiol Genomics 2010 Sep;42A(1):52-60 PMID: 20551144 PMCID: PMC2957771 SCOPUS ID: 2-s2.0-77957122165 06/17/2010       34 Citations
  • Membrane association, mechanism of action, and structure of Arabidopsis embryonic factor 1 (FAC1). (Han BW, Bingman CA, Mahnke DK, Bannen RM, Bednarek SY, Sabina RL, Phillips GN Jr) J Biol Chem 2006 May 26;281(21):14939-47 PMID: 16543243 SCOPUS ID: 2-s2.0-33744951116 03/18/2006       22 Citations
  • Crystallization and preliminary X-ray crystallographic analysis of adenosine 5'-monophosphate deaminase (AMPD) from Arabidopsis thaliana in complex with coformycin 5'-phosphate. (Han BW, Bingman CA, Mahnke DK, Sabina RL, Phillips GN Jr) Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 Aug 01;61(Pt 8):740-2 PMID: 16511144 PMCID: PMC1952363 SCOPUS ID: 2-s2.0-33744954138 03/03/2006       2 Citations
  • Calcium activates erythrocyte AMP deaminase [isoform E (AMPD3)] through a protein-protein interaction between calmodulin and the N-terminal domain of the AMPD3 polypeptide. (Mahnke DK, Sabina RL) Biochemistry 2005 Apr 12;44(14):5551-9 PMID: 15807549 SCOPUS ID: 2-s2.0-16844369577 04/06/2005       15 Citations
  • N-terminal sequence and distal histidine residues are responsible for pH-regulated cytoplasmic membrane binding of human AMP deaminase isoform E. (Mahnke-Zizelman DK, Sabina RL) J Biol Chem 2002 Nov 08;277(45):42654-62 PMID: 12213808 SCOPUS ID: 2-s2.0-0037044753 09/06/2002       11 Citations
  • A G468-T AMPD1 mutant allele contributes to the high incidence of myoadenylate deaminase deficiency in the Caucasian population. (Gross M, Rötzer E, Kölle P, Mortier W, Reichmann H, Goebel HH, Lochmüller H, Pongratz D, Mahnke-Zizelman DK, Sabina RL) Neuromuscul Disord 2002 Aug;12(6):558-65 PMID: 12117480 SCOPUS ID: 2-s2.0-0036314121 07/16/2002       31 Citations
  • Localization of N-terminal sequences in human AMP deaminase isoforms that influence contractile protein binding. (Mahnke-Zizelman DK, Sabina RL) Biochem Biophys Res Commun 2001 Jul 13;285(2):489-95 PMID: 11444869 SCOPUS ID: 2-s2.0-0034816639 07/11/2001       20 Citations
  • Novel aspects of tetramer assembly and N-terminal domain structure and function are revealed by recombinant expression of human AMP deaminase isoforms. (Mahnke-Zizelman DK, Tullson PC, Sabina RL) J Biol Chem 1998 Dec 25;273(52):35118-25 PMID: 9857047 SCOPUS ID: 2-s2.0-0032567534 12/18/1998       30 Citations
  • Genetic and other determinants of AMP deaminase activity in healthy adult skeletal muscle. (Norman B, Mahnke-Zizelman DK, Vallis A, Sabina RL) J Appl Physiol (1985) 1998 Oct;85(4):1273-8 PMID: 9760316 SCOPUS ID: 2-s2.0-0031694689 10/07/1998       52 Citations
  • Regulation of rat AMP deaminase 3 (isoform C) by development and skeletal muscle fibre type. (Mahnke-Zizelman DK, D'cunha J, Wojnar JM, Brogley MA, Sabina RL) Biochem J 1997 Sep 01;326 ( Pt 2)(Pt 2):521-9 PMID: 9291127 PMCID: PMC1218700 SCOPUS ID: 2-s2.0-0030845357 09/18/1997       18 Citations
    • Last update: 09/03/2023