Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Edward M. Barnett PhD, MD

Edward M. Barnett PhD, MD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Ophthalmology

View Curriculum Vitae

Publications (23)

  • In vivo scanning laser fundus and high-resolution OCT imaging of retinal ganglion cell injury in a non-human primate model with an activatable fluorescent-labeled TAT peptide probe. (Qiu X, Gammon ST, Rasmussen C, Pisaneschi F, Kim CBY, Ver Hoeve J, Millward SW, Barnett EM, Nork TM, Kaufman PL, Piwnica-Worms D) PLoS One 2024;19(12):e0313579 PMID: 39642160 PMCID: PMC11623487 SCOPUS ID: 2-s2.0-85211720035 12/06/2024    
  • Apoptosis Detection in Retinal Ganglion Cells Using Quantitative Changes in Multichannel Fluorescence Colocalization. (Qiu X, Gammon ST, Johnson JR, Pisaneschi F, Millward SW, Barnett EM, Piwnica-Worms D) Biosensors (Basel) 2022 Aug 28;12(9) PMID: 36140078 PMCID: PMC9496076 SCOPUS ID: 2-s2.0-85138340626 09/24/2022       2 Citations
  • Single-cell resolution imaging of retinal ganglion cell apoptosis in vivo using a cell-penetrating caspase-activatable peptide probe. (Qiu X, Johnson JR, Wilson BS, Gammon ST, Piwnica-Worms D, Barnett EM) PLoS One 2014;9(2):e88855 PMID: 24586415 PMCID: PMC3931650 SCOPUS ID: 2-s2.0-84896784111 03/04/2014       28 Citations
  • Optic nerve diffusion tensor imaging parameters and their correlation with optic disc topography and disease severity in adult glaucoma patients and controls. (Chang ST, Xu J, Trinkaus K, Pekmezci M, Arthur SN, Song SK, Barnett EM) J Glaucoma 2014;23(8):513-20 PMID: 23632406 PMCID: PMC3800509 SCOPUS ID: 2-s2.0-84916636627 05/02/2013       27 Citations
  • Caspase-activated cell-penetrating peptides reveal temporal coupling between endosomal release and apoptosis in an RGC-5 cell model. (Johnson JR, Kocher B, Barnett EM, Marasa J, Piwnica-Worms D) Bioconjug Chem 2012 Sep 19;23(9):1783-93 PMID: 22900707 PMCID: PMC3447108 SCOPUS ID: 2-s2.0-84866370878 08/21/2012       32 Citations
  • VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans. (Fujikawa K, Iwata T, Inoue K, Akahori M, Kadotani H, Fukaya M, Watanabe M, Chang Q, Barnett EM, Swat W) PLoS One 2010 Feb 04;5(2):e9050 PMID: 20140222 PMCID: PMC2816215 SCOPUS ID: 2-s2.0-77949406694 02/09/2010       54 Citations
  • The incidence of retinal vein occlusion in the ocular hypertension treatment study. (Barnett EM, Fantin A, Wilson BS, Kass MA, Gordon MO, Ocular Hypertension Treatment Study Group) Ophthalmology 2010 Mar;117(3):484-8 PMID: 20031222 PMCID: PMC3077045 SCOPUS ID: 2-s2.0-77049102378 12/25/2009       36 Citations
  • Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 23, (9391-9396) DOI: 10.1073/pnas.0812884106) (Barnett EM, Zhang X, Maxwell D, Chang Q, Piwnica-Worms D) Proceedings of the National Academy of Sciences of the United States of America 14 July 2009;106(28):11819 SCOPUS ID: 2-s2.0-67650921940 07/14/2009       4 Citations
  • Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model. (Barnett EM, Zhang X, Maxwell D, Chang Q, Piwnica-Worms D) Proc Natl Acad Sci U S A 2009 Jun 09;106(23):9391-6 PMID: 19458250 PMCID: PMC2695102 SCOPUS ID: 2-s2.0-67249095097 05/22/2009       104 Citations
  • An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging. (Maxwell D, Chang Q, Zhang X, Barnett EM, Piwnica-Worms D) Bioconjug Chem 2009 Apr;20(4):702-9 PMID: 19331388 PMCID: PMC2672423 SCOPUS ID: 2-s2.0-65249177729 04/01/2009       117 Citations
  • Trabectome (trabeculectomy-internal approach): additional experience and extended follow-up. (Minckler D, Mosaed S, Dustin L, Ms BF, Trabectome Study Group) Trans Am Ophthalmol Soc 2008;106:149-59; discussion 159-60 PMID: 19277230 PMCID: PMC2646453 SCOPUS ID: 2-s2.0-62849090894 01/01/2008       179 Citations
  • Aqueous humor sCD44 concentration and visual field loss in primary open-angle glaucoma. (Nolan MJ, Giovingo MC, Miller AM, Wertz RD, Ritch R, Liebmann JM, Allingham RR, Herndon LW, Wax MB, Smolyak R, Hasan F, Barnett EM, Samples JR, Knepper PA) J Glaucoma 2007 Aug;16(5):419-29 PMID: 17700283 SCOPUS ID: 2-s2.0-34547912469 08/19/2007       38 Citations
  • Asymmetries and visual field summaries as predictors of glaucoma in the ocular hypertension treatment study. (Levine RA, Demirel S, Fan J, Keltner JL, Johnson CA, Kass MA, Ocular Hypertension Treatment Study Group) Invest Ophthalmol Vis Sci 2006 Sep;47(9):3896-903 PMID: 16936102 PMCID: PMC1995656 SCOPUS ID: 2-s2.0-33749158039 08/29/2006       49 Citations
  • Selective cell uptake of modified Tat peptide-fluorophore conjugates in rat retina in ex vivo and in vivo models. (Barnett EM, Elangovan B, Bullok KE, Piwnica-Worms D) Invest Ophthalmol Vis Sci 2006 Jun;47(6):2589-95 PMID: 16723475 SCOPUS ID: 2-s2.0-33745645480 05/26/2006       35 Citations
  • Detection of the free acid of bimatoprost in aqueous humor samples from human eyes treated with bimatoprost before cataract surgery. (Camras CB, Toris CB, Sjoquist B, Milleson M, Thorngren JO, Hejkal TW, Patel N, Barnett EM, Smolyak R, Hasan SF, Hellman C, Meza JL, Wax MB, Stjernschantz J) Ophthalmology 2004 Dec;111(12):2193-8 PMID: 15582073 SCOPUS ID: 2-s2.0-9644276868 12/08/2004       55 Citations
  • Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease. (Pewe L, Wu GF, Barnett EM, Castro RF, Perlman S) Immunity 1996 Sep;5(3):253-62 PMID: 8808680 SCOPUS ID: 2-s2.0-0030249395 09/01/1996       86 Citations
  • Anterograde tracing of trigeminal afferent pathways from the murine tooth pulp to cortex using herpes simplex virus type 1. (Barnett EM, Evans GD, Sun N, Perlman S, Cassell MD) J Neurosci 1995 Apr;15(4):2972-84 PMID: 7536824 PMCID: PMC6577775 SCOPUS ID: 2-s2.0-0028915045 04/01/1995       94 Citations
  • Spread of MHV-JHM from nasal cavity to white matter of spinal cord. Transneuronal movement and involvement of astrocytes. (Perlman S, Sun N, Barnett EM) Adv Exp Med Biol 1995;380:73-8 PMID: 8830549 SCOPUS ID: 2-s2.0-0028841047 01/01/1995       18 Citations
  • Herpes simplex encephalitis in the temporal cortex and limbic system after trigeminal nerve inoculation. (Barnett EM, Jacobsen G, Evans G, Cassell M, Perlman S) J Infect Dis 1994 Apr;169(4):782-6 PMID: 8133092 SCOPUS ID: 2-s2.0-0028344902 04/01/1994       72 Citations
  • Two neurotropic viruses, herpes simplex virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory bulb. (Barnett EM, Cassell MD, Perlman S) Neuroscience 1993 Dec;57(4):1007-25 PMID: 8309541 PMCID: PMC7131965 SCOPUS ID: 2-s2.0-0027366475 12/01/1993       117 Citations
  • The olfactory nerve and not the trigeminal nerve is the major site of CNS entry for mouse hepatitis virus, strain JHM. (Barnett EM, Perlman S) Virology 1993 May;194(1):185-91 PMID: 8386871 SCOPUS ID: 2-s2.0-0027202354 05/01/1993       89 Citations
  • Mouse hepatitis virus and herpes simplex virus move along different CNS pathways. (Perlman S, Barnett E, Jacobsen G) Adv Exp Med Biol 1993;342:313-8 PMID: 7516106 SCOPUS ID: 2-s2.0-0028211650 01/01/1993       8 Citations
  • Schizophrenic deficit in span of apprehension. (Miller MB, Chapman LJ, Chapman JP, Barnett EM) J Abnorm Psychol 1990 Aug;99(3):313-6 PMID: 2212282 SCOPUS ID: 2-s2.0-0025130486 08/01/1990       17 Citations
    • Last update: 02/20/2026