Medical College of Wisconsin
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Elizabeth R. Jacobs MD

Elizabeth R. Jacobs MD profile photo picture

Emeritus Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Medicine Pulmonary

Member of the Cardiovascular Research Center

View Curriculum Vitae

Research Experience

  • Lung Diseases
  • Pulmonary Circulation
  • Pulmonary Infarction
  • Pulmonary Medicine
  • Respiratory Distress Syndrome, Adult

    • Publications (148)

  • In vivo molecular imaging stratifies rats with different susceptibilities to hyperoxic acute lung injury. (Audi SH, Taheri P, Zhao M, Hu K, Jacobs ER, Clough AV) Am J Physiol Lung Cell Mol Physiol 2022 Oct 01;323(4):L410-L422 PMID: 35943727 PMCID: PMC9484995 SCOPUS ID: 2-s2.0-85138459754 08/10/2022       6 Citations
  • Lisinopril Mitigates Radiation-Induced Mitochondrial Defects in Rat Heart and Blood Cells. (Ortiz de Choudens S, Sparapani R, Narayanan J, Lohr N, Gao F, Fish BL, Zielonka M, Gasperetti T, Veley D, Beyer A, Olson J, Jacobs ER, Medhora M) Front Oncol 2022;12:828177 PMID: 35311118 PMCID: PMC8924663 SCOPUS ID: 2-s2.0-85126780777 03/22/2022       5 Citations
  • Depolarized mitochondrial membrane potential and protection with duroquinone in isolated perfused lungs from rats exposed to hyperoxia. (Audi SH, Ganesh S, Taheri P, Zhang X, Dash RK, Clough AV, Jacobs ER) J Appl Physiol (1985) 2022 Feb 01;132(2):346-356 PMID: 34941441 PMCID: PMC8816614 SCOPUS ID: 2-s2.0-85124056241 12/24/2021       8 Citations
  • Assessment of Protection Offered By the NRF2 Pathway Against Hyperoxia-Induced Acute Lung Injury in NRF2 Knockout Rats. (Audi SH, Jacobs ER, Taheri P, Ganesh S, Clough AV) Shock 2022 Feb 01;57(2):274-280 PMID: 34738958 PMCID: PMC8758548 SCOPUS ID: 2-s2.0-85123651681 11/06/2021       15 Citations
  • Autophagy, TERT, and mitochondrial dysfunction in hyperoxia. (Beyer AM, Norwood Toro LE, Hughes WE, Young M, Clough AV, Gao F, Medhora M, Audi SH, Jacobs ER) Am J Physiol Heart Circ Physiol 2021 Nov 01;321(5):H985-H1003 PMID: 34559580 PMCID: PMC8616608 SCOPUS ID: 2-s2.0-85120657950 09/25/2021       30 Citations
  • Evaluation of Radiation-induced Pleural Effusions after Radiotherapy to Support Development of Animal Models of Radiation Pneumonitis. (Aqeel M, Medhora M, Gore E, Borkenhagen J, Klawikowski S, Eastwood D, Banerjee A, Jacobs ER) Health Phys 2021 Oct 01;121(4):434-443 PMID: 34546223 PMCID: PMC8500166 SCOPUS ID: 2-s2.0-85117425583 09/22/2021       4 Citations
  • Corrigendum: Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes. (Gasperetti T, Miller T, Gao F, Narayanan J, Jacobs ER, Szabo A, Cox GN, Orschell CM, Fish BL, Medhora M) Front Pharmacol 2021;12:741485 PMID: 34512365 PMCID: PMC8424069 SCOPUS ID: 2-s2.0-85114725296 09/14/2021       4 Citations
  • Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies. (Puzyrenko A, Jacobs ER, Sun Y, Felix JC, Sheinin Y, Ge L, Lai S, Dai Q, Gantner BN, Nanchal R, North PE, Simpson PM, Rui H, Benjamin IJ) Cell Stress Chaperones 2021 Sep;26(5):859-868 PMID: 34382151 PMCID: PMC8357488 SCOPUS ID: 2-s2.0-85112285201 08/13/2021       24 Citations
  • Molecular Changes in miRNA in Irradiated Rat Kidneys: Role of miR-34a and its Vascular Targets in the Notch Pathway. (Gao F, Dong W, Liu P, Narayanan J, Fish BL, Jacobs ER, Medhora M) Radiat Res 2021 Dec 01;196(6):611-622 PMID: 34330145 PMCID: PMC10416360 SCOPUS ID: 2-s2.0-85121150131 07/31/2021       8 Citations
  • Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes. (Gasperetti T, Miller T, Gao F, Narayanan J, Jacobs ER, Szabo A, Cox GN, Orschell CM, Fish BL, Medhora M) Front Pharmacol 2021;12:634477 PMID: 34079456 PMCID: PMC8165380 SCOPUS ID: 2-s2.0-85107216407 06/04/2021       24 Citations
  • Wound Trauma Exacerbates Acute, but not Delayed, Effects of Radiation in Rats: Mitigation by Lisinopril. (Medhora M, Gasperetti T, Schamerhorn A, Gao F, Narayanan J, Lazarova Z, Jacobs ER, Tarima S, Fish BL) Int J Mol Sci 2020 May 30;21(11) PMID: 32486174 PMCID: PMC7312718 SCOPUS ID: 2-s2.0-85085909627 06/04/2020       13 Citations
  • Quantification of mitochondrial membrane potential in the isolated rat lung using rhodamine 6G. (Audi SH, Cammarata A, Clough AV, Dash RK, Jacobs ER) J Appl Physiol (1985) 2020 Apr 01;128(4):892-906 PMID: 32134711 PMCID: PMC7191506 SCOPUS ID: 2-s2.0-85083624082 03/07/2020       19 Citations
  • Prophylactic supplementation of 20-HETE ameliorates hypoxia/reoxygenation injury in pulmonary vascular endothelial cells by inhibiting apoptosis. (Sugumaran P, Narayanan V, Zhu D, Medhora M, Jacobs ER, Chandramohan Y, Selvaraj V, Dhanasekaran A) Acta Histochem 2020 Jan;122(1):151461 PMID: 31706620 SCOPUS ID: 2-s2.0-85075466040 11/11/2019       12 Citations
  • Pharmacokinetics of 99mTc-HMPAO in isolated perfused rat lungs. (Clough AV, Barry K, Rizzo BM, Jacobs ER, Audi SH) J Appl Physiol (1985) 2019 Nov 01;127(5):1317-1327 PMID: 31414953 PMCID: PMC6957362 SCOPUS ID: 2-s2.0-85074742957 08/16/2019       2 Citations
  • Integrated Computational Model of Lung Tissue Bioenergetics. (Zhang X, Dash RK, Clough AV, Xie D, Jacobs ER, Audi SH) Front Physiol 2019;10:191 PMID: 30906264 PMCID: PMC6418344 SCOPUS ID: 2-s2.0-85066496685 03/25/2019       4 Citations
  • Cardiac Remodeling and Reversible Pulmonary Hypertension During Pneumonitis in Rats after 13-Gy Partial-Body Irradiation with Minimal Bone Marrow Sparing: Effect of Lisinopril. (Jacobs ER, Narayanan J, Fish BL, Gao F, Harmann LM, Bergom C, Gasperetti T, Strande JL, Medhora M) Health Phys 2019 Apr;116(4):558-565 PMID: 30624347 PMCID: PMC6384144 SCOPUS ID: 2-s2.0-85061215751 01/10/2019       22 Citations
  • Delayed Effects of Acute Radiation Exposure (Deare) in Juvenile and Old Rats: Mitigation by Lisinopril. (Medhora M, Gao F, Gasperetti T, Narayanan J, Khan AH, Jacobs ER, Fish BL) Health Phys 2019 Apr;116(4):529-545 PMID: 30624354 PMCID: PMC6384142 SCOPUS ID: 2-s2.0-85061959951 01/10/2019       53 Citations
  • Detection of hydrogen peroxide production in the isolated rat lung using Amplex red. (Audi SH, Friedly N, Dash RK, Beyer AM, Clough AV, Jacobs ER) Free Radic Res 2018 Sep;52(9):1052-1062 PMID: 30175632 PMCID: PMC6298832 SCOPUS ID: 2-s2.0-85054191562 09/04/2018       16 Citations
  • Integrated computational model of the bioenergetics of isolated lung mitochondria. (Zhang X, Dash RK, Jacobs ER, Camara AKS, Clough AV, Audi SH) PLoS One 2018;13(6):e0197921 PMID: 29889855 PMCID: PMC5995348 SCOPUS ID: 2-s2.0-85048330957 06/12/2018       15 Citations
  • Hyperoxia Causes Mitochondrial Fragmentation in Pulmonary Endothelial Cells by Increasing Expression of Pro-Fission Proteins. (Ma C, Beyer AM, Durand M, Clough AV, Zhu D, Norwood Toro L, Terashvili M, Ebben JD, Hill RB, Audi SH, Medhora M, Jacobs ER) Arterioscler Thromb Vasc Biol 2018 Mar;38(3):622-635 PMID: 29419407 PMCID: PMC5823793 SCOPUS ID: 2-s2.0-85047900228 02/09/2018       65 Citations
  • Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging. (Audi SH, Jacobs ER, Zhang X, Camara AKS, Zhao M, Medhora MM, Rizzo B, Clough AV) Shock 2017 Oct;48(4):467-476 PMID: 28915216 PMCID: PMC5636640 SCOPUS ID: 2-s2.0-85017424389 09/16/2017       26 Citations
  • Impact of duration of hypotension prior to norepinephrine initiation in medical intensive care unit patients with septic shock: A prospective observational study. (Patel JJ, Kurman JS, Biesboer A, Taha H, Katz M, Szabo A, Simpson SQ, Jacobs ER) J Crit Care 2017 Aug;40:178-183 PMID: 28412642 SCOPUS ID: 2-s2.0-85020732693 04/17/2017       5 Citations
  • Changes in miRNA in the lung and whole blood after whole thorax irradiation in rats. (Gao F, Liu P, Narayanan J, Yang M, Fish BL, Liu Y, Liang M, Jacobs ER, Medhora M) Sci Rep 2017 Mar 17;7:44132 PMID: 28303893 PMCID: PMC5355888 SCOPUS ID: 2-s2.0-85015404996 03/18/2017       32 Citations
  • Lung injury pathways: Adenosine receptor 2B signaling limits development of ischemic bronchiolitis obliterans organizing pneumonia. (Densmore JC, Schaid TR, Jeziorczak PM, Medhora M, Audi S, Nayak S, Auchampach J, Dwinell MR, Geurts AM, Jacobs ER) Exp Lung Res 2017 Feb;43(1):38-48 PMID: 28266889 PMCID: PMC5831175 SCOPUS ID: 2-s2.0-85014510215 03/08/2017       6 Citations
  • Combined Hydration and Antibiotics with Lisinopril to Mitigate Acute and Delayed High-dose Radiation Injuries to Multiple Organs. (Fish BL, Gao F, Narayanan J, Bergom C, Jacobs ER, Cohen EP, Moulder JE, Orschell CM, Medhora M) Health Phys 2016 Nov;111(5):410-9 PMID: 27682899 PMCID: PMC5065284 SCOPUS ID: 2-s2.0-84991056212 09/30/2016       61 Citations
  • Biomarkers for Radiation Pneumonitis Using Noninvasive Molecular Imaging. (Medhora M, Haworth S, Liu Y, Narayanan J, Gao F, Zhao M, Audi S, Jacobs ER, Fish BL, Clough AV) J Nucl Med 2016 Aug;57(8):1296-301 PMID: 27033892 PMCID: PMC5053021 SCOPUS ID: 2-s2.0-84982816391 04/02/2016       37 Citations
  • 99MTc-Hexamethylpropyleneamine Oxime Imaging for Early Detection of Acute Lung Injury in Rats Exposed to Hyperoxia or Lipopolysaccharide Treatment. (Audi SH, Clough AV, Haworth ST, Medhora M, Ranji M, Densmore JC, Jacobs ER) Shock 2016 Oct;46(4):420-30 PMID: 26974426 PMCID: PMC5014734 SCOPUS ID: 2-s2.0-84961231173 03/15/2016       21 Citations
  • Involvement of gap junctions between smooth muscle cells in sustained hypoxic pulmonary vasoconstriction development: a potential role for 15-HETE and 20-HETE. (Kizub IV, Lakhkar A, Dhagia V, Joshi SR, Jiang H, Wolin MS, Falck JR, Koduru SR, Errabelli R, Jacobs ER, Schwartzman ML, Gupte SA) Am J Physiol Lung Cell Mol Physiol 2016 Apr 15;310(8):L772-83 PMID: 26895643 PMCID: PMC4836112 SCOPUS ID: 2-s2.0-84984605076 02/21/2016       18 Citations
  • Acute myocardial infarction: a national analysis of the weekend effect over time. (Kumar G, Deshmukh A, Sakhuja A, Taneja A, Kumar N, Jacobs E, Nanchal R, Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators) J Am Coll Cardiol 2015 Jan 20;65(2):217-8 PMID: 25593065 SCOPUS ID: 2-s2.0-84922667193 01/17/2015       35 Citations
  • Novel Flurometric Tool to Assess Mitochondrial Redox State of Isolated Perfused Rat Lungs after Exposure to Hyperoxia. (Sepehr R, Audi SH, Staniszewski KS, Haworth ST, Jacobs ER, Ranji M) IEEE J Transl Eng Health Med 2013 Oct 16;1 PMID: 25379360 PMCID: PMC4219590 SCOPUS ID: 2-s2.0-84943765937 11/08/2014       13 Citations
  • Whole-thorax irradiation induces hypoxic respiratory failure, pleural effusions and cardiac remodeling. (Medhora M, Gao F, Glisch C, Narayanan J, Sharma A, Harmann LM, Lawlor MW, Snyder LA, Fish BL, Down JD, Moulder JE, Strande JL, Jacobs ER) J Radiat Res 2015 Mar;56(2):248-60 PMID: 25368342 PMCID: PMC4380043 SCOPUS ID: 2-s2.0-84942308898 11/05/2014       41 Citations
  • Model development and use of ACE inhibitors for preclinical mitigation of radiation-induced injury to multiple organs. (Medhora M, Gao F, Wu Q, Molthen RC, Jacobs ER, Moulder JE, Fish BL) Radiat Res 2014 Nov;182(5):545-55 PMID: 25361399 PMCID: PMC4261643 SCOPUS ID: 2-s2.0-84914166194 11/02/2014       48 Citations
  • Early Trophic Enteral Nutrition Is Associated With Improved Outcomes in Mechanically Ventilated Patients With Septic Shock: A Retrospective Review. (Patel JJ, Kozeniecki M, Biesboer A, Peppard W, Ray AS, Thomas S, Jacobs ER, Nanchal R, Kumar G) J Intensive Care Med 2016 Aug;31(7):471-7 PMID: 25315218 SCOPUS ID: 2-s2.0-84978069680 10/16/2014       56 Citations
  • In vivo detection of hyperoxia-induced pulmonary endothelial cell death using (99m)Tc-duramycin. (Audi SH, Jacobs ER, Zhao M, Roerig DL, Haworth ST, Clough AV) Nucl Med Biol 2015 Jan;42(1):46-52 PMID: 25218023 PMCID: PMC4383294 SCOPUS ID: 2-s2.0-84920487394 09/15/2014       32 Citations
  • Enhanced survival from radiation pneumonitis by combined irradiation to the skin. (Gao F, Fish BL, Szabo A, Schock A, Narayanan J, Jacobs ER, Moulder JE, Lazarova Z, Medhora M) Int J Radiat Biol 2014 Sep;90(9):753-61 PMID: 24827855 PMCID: PMC4380176 SCOPUS ID: 2-s2.0-84907045554 05/16/2014       10 Citations
  • Hypoxia preconditioning increases survival and decreases expression of Toll-like receptor 4 in pulmonary artery endothelial cells exposed to lipopolysaccharide. (Ali I, Nanchal R, Husnain F, Audi S, Konduri GG, Densmore JC, Medhora M, Jacobs ER) Pulm Circ 2013 Sep;3(3):578-88 PMID: 24618542 PMCID: PMC4070795 SCOPUS ID: 2-s2.0-84973361991 03/13/2014       19 Citations
  • Clinical CVVH model removes endothelium-derived microparticles from circulation. (Abdelhafeez AH, Jeziorczak PM, Schaid TR, Hoefs SL, Kaul S, Nanchal R, Jacobs ER, Densmore JC) J Extracell Vesicles 2014;3 PMID: 24596654 PMCID: PMC3938801 SCOPUS ID: 2-s2.0-84907564112 03/07/2014       12 Citations
  • The association of lacking insurance with outcomes of severe sepsis: retrospective analysis of an administrative database*. (Kumar G, Taneja A, Majumdar T, Jacobs ER, Whittle J, Nanchal R, Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators) Crit Care Med 2014 Mar;42(3):583-91 PMID: 24152590 PMCID: PMC4990450 SCOPUS ID: 2-s2.0-84894481253 10/25/2013       46 Citations
  • Enalapril mitigates radiation-induced pneumonitis and pulmonary fibrosis if started 35 days after whole-thorax irradiation. (Gao F, Fish BL, Moulder JE, Jacobs ER, Medhora M) Radiat Res 2013 Nov;180(5):546-52 PMID: 24131041 PMCID: PMC3895940 SCOPUS ID: 2-s2.0-84888141459 10/18/2013       50 Citations
  • Utilization of mechanical ventilation for asthma exacerbations: analysis of a national database. (Nanchal R, Kumar G, Majumdar T, Taneja A, Patel J, Dagar G, Jacobs ER, Whittle J) Respir Care 2014 May;59(5):644-53 PMID: 24106317 PMCID: PMC4580276 SCOPUS ID: 2-s2.0-84899740023 10/10/2013       40 Citations
  • The association of serum bilirubin levels on the outcomes of severe sepsis. (Patel JJ, Taneja A, Niccum D, Kumar G, Jacobs E, Nanchal R) J Intensive Care Med 2015 Jan;30(1):23-9 PMID: 23753252 SCOPUS ID: 2-s2.0-84916897897 06/12/2013       99 Citations
  • Fluorometry of ischemia reperfusion injury in rat lungs in vivo (Sepehr R, Staniszewski K, Jacobs ER, Audi S, Ranji M) Progress in Biomedical Optics and Imaging Proceedings of SPIE 2013;8580 SCOPUS ID: 2-s2.0-84878685351 06/12/2013       1 Citation
  • Enalapril mitigates focal alveolar lesions, a histological marker of late pulmonary injury by radiation to the lung. (Gao F, Narayanan J, Joneikis C, Fish BL, Szabo A, Moulder JE, Molthen RC, Jacobs ER, Rao RN, Medhora M) Radiat Res 2013 Apr;179(4):465-74 PMID: 23480564 PMCID: PMC3697111 SCOPUS ID: 2-s2.0-84876241819 03/14/2013       16 Citations
  • Rattus model utilizing selective pulmonary ischemia induces bronchiolitis obliterans organizing pneumonia. (Densmore JC, Jeziorczak PM, Clough AV, Pritchard KA Jr, Cummens B, Medhora M, Rao A, Jacobs ER) Shock 2013 Mar;39(3):271-7 PMID: 23364425 PMCID: PMC3578046 SCOPUS ID: 2-s2.0-84874256858 02/01/2013       10 Citations
  • Outcomes of morbidly obese patients receiving invasive mechanical ventilation: a nationwide analysis. (Kumar G, Majumdar T, Jacobs ER, Danesh V, Dagar G, Deshmukh A, Taneja A, Nanchal R, from the Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators) Chest 2013 Jul;144(1):48-54 PMID: 23349057 PMCID: PMC4694107 SCOPUS ID: 2-s2.0-84880057124 01/26/2013       30 Citations
  • Development, anatomy, and physiology of the lungs (Tomic R, Antonescu-Turcu A, Jacobs ER) Principles of Deglutition A Multidisciplinary Text for Swallowing and Its Disorders 1 January 2013:199-214 SCOPUS ID: 2-s2.0-84955700049 01/01/2013       5 Citations
  • Surface fluorescence studies of tissue mitochondrial redox state in isolated perfused rat lungs. (Staniszewski K, Audi SH, Sepehr R, Jacobs ER, Ranji M) Ann Biomed Eng 2013 Apr;41(4):827-36 PMID: 23238793 PMCID: PMC3606690 SCOPUS ID: 2-s2.0-84876466897 12/15/2012       22 Citations
  • Short-term treatment with a SOD/catalase mimetic, EUK-207, mitigates pneumonitis and fibrosis after single-dose total-body or whole-thoracic irradiation. (Gao F, Fish BL, Szabo A, Doctrow SR, Kma L, Molthen RC, Moulder JE, Jacobs ER, Medhora M) Radiat Res 2012 Nov;178(5):468-80 PMID: 23020094 PMCID: PMC3678766 SCOPUS ID: 2-s2.0-84868620912 10/02/2012       43 Citations
  • Mitigation of radiation induced pulmonary vascular injury by delayed treatment with captopril. (Molthen RC, Wu Q, Fish BL, Moulder JE, Jacobs ER, Medhora MM) Respirology 2012 Nov;17(8):1261-8 PMID: 22882664 PMCID: PMC3848310 SCOPUS ID: 2-s2.0-84867930386 08/14/2012       30 Citations
  • Acute effects of prostaglandin E1 and E2 on vascular reactivity and blood flow in situ in the chick chorioallantoic membrane. (Harland DR, Lorenz LD, Fay K, Dunn BE, Gruenloh SK, Narayanan J, Jacobs ER, Medhora M) Prostaglandins Leukot Essent Fatty Acids 2012;87(2-3):79-89 PMID: 22858445 PMCID: PMC3839254 SCOPUS ID: 2-s2.0-84865387236 08/04/2012       4 Citations
  • Dose-modifying factor for captopril for mitigation of radiation injury to normal lung. (Medhora M, Gao F, Fish BL, Jacobs ER, Moulder JE, Szabo A) J Radiat Res 2012 Jul;53(4):633-40 PMID: 22843631 PMCID: PMC3393339 SCOPUS ID: 2-s2.0-84872114086 07/31/2012       45 Citations
  • Tissue protection and endothelial cell signaling by 20-HETE analogs in intact ex vivo lung slices. (Jacobs ER, Bodiga S, Ali I, Falck AM, Falck JR, Medhora M, Dhanasekaran A) Exp Cell Res 2012 Oct 01;318(16):2143-52 PMID: 22687879 PMCID: PMC3749092 SCOPUS ID: 2-s2.0-84864296910 06/13/2012       10 Citations
  • Optical studies of tissue mitochondrial redox in isolated perfused rat lungs (Sepehr R, Staniszewski K, Jacobs ER, Audi S, Ranji M) Progress in Biomedical Optics and Imaging Proceedings of SPIE 2012;8207 SCOPUS ID: 2-s2.0-84860711124 05/14/2012    
  • Optical imaging of tissue mitochondrial redox state in intact rat lungs in two models of pulmonary oxidative stress. (Sepehr R, Staniszewski K, Maleki S, Jacobs ER, Audi S, Ranji M) J Biomed Opt 2012 Apr;17(4):046010 PMID: 22559688 PMCID: PMC3380956 SCOPUS ID: 2-s2.0-84865605652 05/09/2012       37 Citations
  • Pulmonary embolism: the weekend effect. (Nanchal R, Kumar G, Taneja A, Patel J, Deshmukh A, Tarima S, Jacobs ER, Whittle J, from the Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators) Chest 2012 Sep;142(3):690-696 PMID: 22459777 PMCID: PMC4694190 SCOPUS ID: 2-s2.0-84865851848 03/31/2012       80 Citations
  • A soluble epoxide hydrolase inhibitor--8-HUDE increases pulmonary vasoconstriction through inhibition of K(ATP) channels. (Liu Y, Zhang J, Yu L, Cao F, Rao J, Li J, Jiang C, Falck JR, Jacobs ER, Zhu D) Pulm Pharmacol Ther 2012 Feb;25(1):69-76 PMID: 22155000 SCOPUS ID: 2-s2.0-84856780301 12/14/2011       5 Citations
  • Protection by 20-5,14-HEDGE against surgically induced ischemia reperfusion lung injury in rats. (Ali I, Gruenloh S, Gao Y, Clough A, Falck JR, Medhora M, Jacobs ER) Ann Thorac Surg 2012 Jan;93(1):282-8 PMID: 22115333 PMCID: PMC3268555 SCOPUS ID: 2-s2.0-84055189348 11/26/2011       17 Citations
  • Mitigation of late renal and pulmonary injury after hematopoietic stem cell transplantation. (Cohen EP, Bedi M, Irving AA, Jacobs E, Tomic R, Klein J, Lawton CA, Moulder JE) Int J Radiat Oncol Biol Phys 2012 May 01;83(1):292-6 PMID: 22104363 PMCID: PMC3299939 SCOPUS ID: 2-s2.0-84859878438 11/23/2011       62 Citations
  • Radiation damage to the lung: mitigation by angiotensin-converting enzyme (ACE) inhibitors. (Medhora M, Gao F, Jacobs ER, Moulder JE) Respirology 2012 Jan;17(1):66-71 PMID: 22023053 PMCID: PMC3245332 SCOPUS ID: 2-s2.0-84255176558 10/26/2011       99 Citations
  • Nationwide trends of severe sepsis in the 21st century (2000-2007). (Kumar G, Kumar N, Taneja A, Kaleekal T, Tarima S, McGinley E, Jimenez E, Mohan A, Khan RA, Whittle J, Jacobs E, Nanchal R, Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators) Chest 2011 Nov;140(5):1223-1231 PMID: 21852297 SCOPUS ID: 2-s2.0-81055145174 08/20/2011       536 Citations
  • Stable EET urea agonist and soluble epoxide hydrolase inhibitor regulate rat pulmonary arteries through TRPCs. (Liu Y, Wang R, Li J, Rao J, Li W, Falck JR, Manthati VL, Medhora M, Jacobs ER, Zhu D) Hypertens Res 2011 May;34(5):630-9 PMID: 21307870 PMCID: PMC4548928 SCOPUS ID: 2-s2.0-79955600318 02/11/2011       19 Citations
  • Effects of a localized high-flow anastomosis between the aorta and left lower lobe pulmonary artery on great vessel flow and pulmonary arterial reactivity in the contralateral lung. (Somberg L, Nirula R, Bousamra M 2nd, Friesema J, Zhu D, Medhora M, Jacobs ER) J Thorac Cardiovasc Surg 2011 Feb;141(2):407-12 PMID: 21075384 PMCID: PMC3022966 SCOPUS ID: 2-s2.0-78751591713 11/16/2010       1 Citation
  • Mechanisms underlying increased reactivity of pulmonary arteries contralateral to a localized high-flow anastomosis. (Pfister S, Somberg L, Lowry T, Gao Y, Medhora M, Jacobs ER) J Thorac Cardiovasc Surg 2011 Feb;141(2):425-31 PMID: 21075383 PMCID: PMC3052931 SCOPUS ID: 2-s2.0-78751601116 11/16/2010       2 Citations
  • 8,9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway. (Ma J, Zhang L, Li S, Liu S, Ma C, Li W, Falck JR, Manthati VL, Reddy DS, Medhora M, Jacobs ER, Zhu D) Exp Cell Res 2010 Aug 15;316(14):2340-53 PMID: 20493836 PMCID: PMC2927814 SCOPUS ID: 2-s2.0-77954386544 05/25/2010       22 Citations
  • Cellular inflammatory infiltrate in pneumonitis induced by a single moderate dose of thoracic x radiation in rats. (Szabo S, Ghosh SN, Fish BL, Bodiga S, Tomic R, Kumar G, Morrow NV, Moulder JE, Jacobs ER, Medhora M) Radiat Res 2010 Apr;173(4):545-56 PMID: 20334527 PMCID: PMC2904484 SCOPUS ID: 2-s2.0-77950256999 03/26/2010       41 Citations
  • 20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H2O2, and PI3-kinase/Akt. (Bodiga S, Gruenloh SK, Gao Y, Manthati VL, Dubasi N, Falck JR, Medhora M, Jacobs ER) Am J Physiol Lung Cell Mol Physiol 2010 Apr;298(4):L564-74 PMID: 20061439 PMCID: PMC2853341 SCOPUS ID: 2-s2.0-77950334333 01/12/2010       32 Citations
  • Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis. (Ghosh SN, Zhang R, Fish BL, Semenenko VA, Li XA, Moulder JE, Jacobs ER, Medhora M) Int J Radiat Oncol Biol Phys 2009 Dec 01;75(5):1528-36 PMID: 19931735 PMCID: PMC2800372 SCOPUS ID: 2-s2.0-71649101555 11/26/2009       101 Citations
  • Prolonged hypothermia as a bridge to recovery for cerebral edema and intracranial hypertension associated with fulminant hepatic failure. (Jacob S, Khan A, Jacobs ER, Kandiah P, Nanchal R) Neurocrit Care 2009;11(2):242-6 PMID: 19728177 SCOPUS ID: 2-s2.0-70350575434 09/04/2009       16 Citations
  • Imaging radiation pneumonitis in a rat model of a radiological terrorism incident (Molthen R, Wu QP, Krenz G, Medhora M, Jacobs E, Moulder JE) Progress in Biomedical Optics and Imaging Proceedings of SPIE 2009;7262 SCOPUS ID: 2-s2.0-67249145940 06/22/2009       1 Citation
  • Vascular injury after whole thoracic x-ray irradiation in the rat. (Ghosh SN, Wu Q, Mäder M, Fish BL, Moulder JE, Jacobs ER, Medhora M, Molthen RC) Int J Radiat Oncol Biol Phys 2009 May 01;74(1):192-9 PMID: 19362237 PMCID: PMC2745917 SCOPUS ID: 2-s2.0-64049089817 04/14/2009       63 Citations
  • Protective actions of epoxyeicosatrienoic acid: dual targeting of cardiovascular PI3K and KATP channels. (Bodiga S, Zhang R, Jacobs DE, Larsen BT, Tampo A, Manthati VL, Kwok WM, Zeldin DC, Falck JR, Gutterman DD, Jacobs ER, Medhora MM) J Mol Cell Cardiol 2009 Jun;46(6):978-88 PMID: 19336274 PMCID: PMC2796716 SCOPUS ID: 2-s2.0-67349200006 04/02/2009       45 Citations
  • 20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells. (Dhanasekaran A, Bodiga S, Gruenloh S, Gao Y, Dunn L, Falck JR, Buonaccorsi JN, Medhora M, Jacobs ER) Am J Physiol Heart Circ Physiol 2009 Mar;296(3):H777-86 PMID: 19136601 PMCID: PMC2660237 SCOPUS ID: 2-s2.0-64049113217 01/13/2009       45 Citations
  • Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism. (Zhang R, Mio Y, Pratt PF, Lohr N, Warltier DC, Whelan HT, Zhu D, Jacobs ER, Medhora M, Bienengraeber M) J Mol Cell Cardiol 2009 Jan;46(1):4-14 PMID: 18930064 PMCID: PMC2640422 SCOPUS ID: 2-s2.0-57149112732 10/22/2008       94 Citations
  • Structural and functional alterations in the rat lung following whole thoracic irradiation with moderate doses: injury and recovery. (Zhang R, Ghosh SN, Zhu D, North PE, Fish BL, Morrow NV, Lowry T, Nanchal R, Jacobs ER, Moulder JE, Medhora M) Int J Radiat Biol 2008 Jun;84(6):487-97 PMID: 18470747 PMCID: PMC2435093 SCOPUS ID: 2-s2.0-45849110724 05/13/2008       47 Citations
  • 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells. (Medhora M, Chen Y, Gruenloh S, Harland D, Bodiga S, Zielonka J, Gebremedhin D, Gao Y, Falck JR, Anjaiah S, Jacobs ER) Am J Physiol Lung Cell Mol Physiol 2008 May;294(5):L902-11 PMID: 18296498 PMCID: PMC2586843 SCOPUS ID: 2-s2.0-45849122077 02/26/2008       69 Citations
  • Role of JNK in network formation of human lung microvascular endothelial cells. (Medhora M, Dhanasekaran A, Pratt PF Jr, Cook CR, Dunn LK, Gruenloh SK, Jacobs ER) Am J Physiol Lung Cell Mol Physiol 2008 Apr;294(4):L676-85 PMID: 18263671 PMCID: PMC2904476 SCOPUS ID: 2-s2.0-42049122785 02/12/2008       18 Citations
  • Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia. (Dhanasekaran A, Gruenloh SK, Buonaccorsi JN, Zhang R, Gross GJ, Falck JR, Patel PK, Jacobs ER, Medhora M) Am J Physiol Heart Circ Physiol 2008 Feb;294(2):H724-35 PMID: 18055514 PMCID: PMC2443685 SCOPUS ID: 2-s2.0-39149128273 12/07/2007       165 Citations
  • From the authors [3] (Carey MA, Card JW, Voltz JW, Jacobs ER, Dakhama A, Larsen G, Gelfand EW, Zeldin DC) American Journal of Respiratory and Critical Care Medicine 15 July 2007;176(2):215-216 SCOPUS ID: 2-s2.0-34447300455 07/15/2007    
  • Emerging mechanisms for growth and protection of the vasculature by cytochrome P450-derived products of arachidonic acid and other eicosanoids. (Medhora M, Dhanasekaran A, Gruenloh SK, Dunn LK, Gabrilovich M, Falck JR, Harder DR, Jacobs ER, Pratt PF) Prostaglandins Other Lipid Mediat 2007 Jan;82(1-4):19-29 PMID: 17164129 SCOPUS ID: 2-s2.0-33845313333 12/14/2006       47 Citations
  • Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice. (Carey MA, Card JW, Bradbury JA, Moorman MP, Haykal-Coates N, Gavett SH, Graves JP, Walker VR, Flake GP, Voltz JW, Zhu D, Jacobs ER, Dakhama A, Larsen GL, Loader JE, Gelfand EW, Germolec DR, Korach KS, Zeldin DC) Am J Respir Crit Care Med 2007 Jan 15;175(2):126-35 PMID: 17095746 PMCID: PMC1899278 SCOPUS ID: 2-s2.0-33846286093 11/11/2006       119 Citations
  • Contribution of epoxyeicosatrienoic acids to the hypoxia-induced activation of Ca2+ -activated K+ channel current in cultured rat hippocampal astrocytes. (Yamaura K, Gebremedhin D, Zhang C, Narayanan J, Hoefert K, Jacobs ER, Koehler RC, Harder DR) Neuroscience 2006 Dec;143(3):703-16 PMID: 17027168 SCOPUS ID: 2-s2.0-33750978403 10/10/2006       46 Citations
  • VEGF-induced relaxation of pulmonary arteries is mediated by endothelial cytochrome P-450 hydroxylase. (Jacobs ER, Zhu D, Gruenloh S, Lopez B, Medhora M) Am J Physiol Lung Cell Mol Physiol 2006 Sep;291(3):L369-77 PMID: 16679379 SCOPUS ID: 2-s2.0-33748435644 05/09/2006       29 Citations
  • Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells. (Chen Y, Medhora M, Falck JR, Pritchard KA Jr, Jacobs ER) Am J Physiol Lung Cell Mol Physiol 2006 Sep;291(3):L378-85 PMID: 16679377 SCOPUS ID: 2-s2.0-33748439111 05/09/2006       52 Citations
  • Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature. (Dhanasekaran A, Al-Saghir R, Lopez B, Zhu D, Gutterman DD, Jacobs ER, Medhora M) Am J Physiol Heart Circ Physiol 2006 Aug;291(2):H517-31 PMID: 16617127 SCOPUS ID: 2-s2.0-33746790148 04/18/2006       61 Citations
  • Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs). (Dunn LK, Gruenloh SK, Dunn BE, Reddy DS, Falck JR, Jacobs ER, Medhora M) Anat Rec A Discov Mol Cell Evol Biol 2005 Aug;285(2):771-80 PMID: 15952186 SCOPUS ID: 2-s2.0-23244463577 06/14/2005       16 Citations
  • P2Y purine receptor responses and expression in the pulmonary circulation of juvenile rabbits. (Konduri GG, Bakhutashvili I, Frenn R, Chandrasekhar I, Jacobs ER, Khanna AK) Am J Physiol Heart Circ Physiol 2004 Jul;287(1):H157-64 PMID: 14962841 SCOPUS ID: 2-s2.0-1942498685 02/14/2004       28 Citations
  • Increased epoxyeicosatrienoic acid formation in the rat kidney during liver cirrhosis. (Miyazono M, Zhu D, Nemenoff R, Jacobs ER, Carter EP) J Am Soc Nephrol 2003 Jul;14(7):1766-75 PMID: 12819236 SCOPUS ID: 2-s2.0-0037530612 06/24/2003       12 Citations
  • Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries. (Zhu D, Medhora M, Campbell WB, Spitzbarth N, Baker JE, Jacobs ER) Circ Res 2003 May 16;92(9):992-1000 PMID: 12690037 SCOPUS ID: 2-s2.0-0037687982 04/12/2003       143 Citations
  • Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells. (Medhora M, Daniels J, Mundey K, Fisslthaler B, Busse R, Jacobs ER, Harder DR) Am J Physiol Heart Circ Physiol 2003 Jan;284(1):H215-24 PMID: 12388259 SCOPUS ID: 2-s2.0-0037230201 10/22/2002       109 Citations
  • Nitric oxide contributes to 20-HETE-induced relaxation of pulmonary arteries. (Yu M, McAndrew RP, Al-Saghir R, Maier KG, Medhora M, Roman RJ, Jacobs ER) J Appl Physiol (1985) 2002 Oct;93(4):1391-9 PMID: 12235040 SCOPUS ID: 2-s2.0-0036785969 09/18/2002       40 Citations
  • Serotonin and serotonin receptor expression in the aorta of carotid intact and denervated newborns. (Serra A, Brozoski D, Simeon T, Yi J, Bastasic J, Franciosi R, Jacobs ER, Forster HV) Respir Physiol Neurobiol 2002 Sep 04;132(3):253-64 PMID: 12208084 SCOPUS ID: 2-s2.0-0037019778 09/05/2002       8 Citations
  • CYP4A mRNA, protein, and product in rat lungs: novel localization in vascular endothelium. (Zhu D, Zhang C, Medhora M, Jacobs ER) J Appl Physiol (1985) 2002 Jul;93(1):330-7 PMID: 12070222 SCOPUS ID: 2-s2.0-0035986058 06/19/2002       56 Citations
  • Upregulation of collagens detected by gene array in a model of flow-induced pulmonary vascular remodeling. (Medhora M, Bousamra M 2nd, Zhu D, Somberg L, Jacobs ER) Am J Physiol Heart Circ Physiol 2002 Feb;282(2):H414-22 PMID: 11788387 SCOPUS ID: 2-s2.0-0036084720 01/15/2002       37 Citations
  • Effects of carotid and aortic denervation on serotonin and serotonin receptors expression in chemosensitive areas of newborn mammal aortas (Serra A, Brozoski D, Franciosi R, Jacobs E, Roesner D, Forster HV) Langenbeck S Archives of Surgery 2001;386(6):474 SCOPUS ID: 2-s2.0-33746379305 12/01/2001    
  • The lung HETEs (and EETs) up. (Jacobs ER, Zeldin DC) Am J Physiol Heart Circ Physiol 2001 Jan;280(1):H1-H10 PMID: 11123211 SCOPUS ID: 2-s2.0-0035013924 12/21/2000       78 Citations
  • Hypoxic pulmonary vasoconstriction is modified by P-450 metabolites (Zhu D, Birks EK, Dawson CA, Patel M, Falck JR, Presberg K, Roman RJ, Jacobs ER) American Journal of Physiology October 2000;279(4 PART 2):H1526-H1533 SCOPUS ID: 2-s2.0-0033713364 10/01/2000       54 Citations
  • Hypoxic pulmonary vasoconstriction is modified by P-450 metabolites. (Zhu D, Birks EK, Dawson CA, Patel M, Falck JR, Presberg K, Roman RJ, Jacobs ER) Am J Physiol Heart Circ Physiol 2000 Oct;279(4):H1526-33 PMID: 11009437 SCOPUS ID: 2-s2.0-34447616694 09/29/2000       10 Citations
  • Systemic lobar shunting induces advanced pulmonary vasculopathy. (Bousamra M 2nd, Rossi R, Jacobs E, Parviz M, Busch C, Nelin LD, Haworth S, Dawson CA) J Thorac Cardiovasc Surg 2000 Jul;120(1):88-98 PMID: 10884660 SCOPUS ID: 2-s2.0-0034234368 07/08/2000       17 Citations
  • Response of the lungs to aspiration. (Effros RM, Jacobs ER, Schapira RM, Biller J) Am J Med 2000 Mar 06;108 Suppl 4a:15S-19S PMID: 10718446 SCOPUS ID: 2-s2.0-0034611349 03/16/2000       24 Citations
  • Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. (Zhu D, Bousamra M 2nd, Zeldin DC, Falck JR, Townsley M, Harder DR, Roman RJ, Jacobs ER) Am J Physiol Lung Cell Mol Physiol 2000 Feb;278(2):L335-43 PMID: 10666118 SCOPUS ID: 2-s2.0-0034014269 02/09/2000       90 Citations
  • Increasing airway pressures can promote transvascular edema reabsorption. (Effros RM, Jacobs ER, Schapira RM, Lin W, Presberg K) Chest 1999 Jul;116(1 Suppl):30S-31S PMID: 10424574 SCOPUS ID: 2-s2.0-0032779708 07/29/1999       3 Citations
  • Effects of chronic pulmonary overcirculation on pulmonary vasomotor tone. (Parviz M, Bousamra M 2nd, Chammas JH, Birks EK, Presberg KW, Jacobs ER, Nelin LD) Ann Thorac Surg 1999 Feb;67(2):522-7 PMID: 10197682 SCOPUS ID: 2-s2.0-0032929882 04/10/1999       21 Citations
  • Airway synthesis of 20-hydroxyeicosatetraenoic acid: metabolism by cyclooxygenase to a bronchodilator. (Jacobs ER, Effros RM, Falck JR, Reddy KM, Campbell WB, Zhu D) Am J Physiol 1999 Feb;276(2):L280-8 PMID: 9950890 SCOPUS ID: 2-s2.0-0032991405 02/10/1999       34 Citations
  • Stop-flow studies of solute uptake in rat lungs. (Effros RM, Schapira R, Presberg K, Ozker K, Jacobs ER) J Appl Physiol (1985) 1998 Sep;85(3):986-92 PMID: 9729574 SCOPUS ID: 2-s2.0-0031666140 09/08/1998       5 Citations
  • Tissue sources of cytochrome P450 4A and 20-HETE synthesis in rabbit lungs. (Zhu D, Effros RM, Harder DR, Roman RJ, Jacobs ER) Am J Respir Cell Mol Biol 1998 Jul;19(1):121-8 PMID: 9651188 SCOPUS ID: 2-s2.0-0032111675 07/03/1998       41 Citations
  • Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca2+ current. (Gebremedhin D, Lange AR, Narayanan J, Aebly MR, Jacobs ER, Harder DR) J Physiol 1998 Mar 15;507 ( Pt 3)(Pt 3):771-81 PMID: 9508838 PMCID: PMC2230829 SCOPUS ID: 2-s2.0-0032521122 05/23/1998       183 Citations
  • Stop-flow studies of distribution of filtration in rat lungs. (Lin W, Jacobs E, Schapira RM, Presberg K, Effros RM) J Appl Physiol (1985) 1998 Jan;84(1):47-52 PMID: 9451616 SCOPUS ID: 2-s2.0-0031908663 02/06/1998       12 Citations
  • Loss of inducible nitric oxide synthase and cytochrome P450-4A in shunt induced pulmonary hypertension (Parviz M, Birks E, Chammas J, Nelin L, Jacobs E, Bousama M) FASEB Journal 1997;11(3):A135 SCOPUS ID: 2-s2.0-33750121226 12/01/1997    
  • Water transport and the distribution of aquaporin-1 in pulmonary air spaces. (Effros RM, Darin C, Jacobs ER, Rogers RA, Krenz G, Schneeberger EE) J Appl Physiol (1985) 1997 Sep;83(3):1002-16 PMID: 9292489 SCOPUS ID: 2-s2.0-0030770795 09/18/1997       52 Citations
  • Human pulmonary arteries dilate to 20-HETE, an endogenous eicosanoid of lung tissue. (Birks EK, Bousamra M, Presberg K, Marsh JA, Effros RM, Jacobs ER) Am J Physiol 1997 May;272(5 Pt 1):L823-9 PMID: 9176244 SCOPUS ID: 2-s2.0-0030914663 05/01/1997       60 Citations
  • Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction. (Davies PF, Barbee KA, Volin MV, Robotewskyj A, Chen J, Joseph L, Griem ML, Wernick MN, Jacobs E, Polacek DC, dePaola N, Barakat AI) Annu Rev Physiol 1997;59:527-49 PMID: 9074776 SCOPUS ID: 2-s2.0-8244259183 01/01/1997       295 Citations
  • Bioassay of endothelium derived cytochrome p450-dependent hyperpolarizing factor from bovine coronary arteries (Harder DR, Campbell WB, Pratt PF, Jacobs ER, Gebremedhin D) FASEB Journal 1996;10(3):A301 SCOPUS ID: 2-s2.0-4243829359 12/01/1996       1 Citation
  • Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity. (Zou AP, Fleming JT, Falck JR, Jacobs ER, Gebremedhin D, Harder DR, Roman RJ) Am J Physiol 1996 May;270(5 Pt 2):F822-32 PMID: 8928844 SCOPUS ID: 2-s2.0-0029888211 05/01/1996       195 Citations
  • Coexistence of two types of Ca(2+)-activated K+ channels in rat renal arterioles. (Gebremedhin D, Kaldunski M, Jacobs ER, Harder DR, Roman RJ) Am J Physiol 1996 Jan;270(1 Pt 2):F69-81 PMID: 8769824 SCOPUS ID: 2-s2.0-0030062899 01/01/1996       91 Citations
  • 20-HETE is an endogenous inhibitor of the large-conductance Ca(2+)-activated K+ channel in renal arterioles. (Zou AP, Fleming JT, Falck JR, Jacobs ER, Gebremedhin D, Harder DR, Roman RJ) Am J Physiol 1996 Jan;270(1 Pt 2):R228-37 PMID: 8769806 SCOPUS ID: 2-s2.0-0030029461 01/01/1996       295 Citations
  • Shear activated channels in cell-attached patches of cultured bovine aortic endothelial cells. (Jacobs ER, Cheliakine C, Gebremedhin D, Birks EK, Davies PF, Harder DR) Pflugers Arch 1995 Nov;431(1):129-31 PMID: 8584410 SCOPUS ID: 2-s2.0-0028840911 11/01/1995       77 Citations
  • Continuous measurements of changes in pulmonary capillary surface area with 201Tl infusions. (Effros RM, Hacker A, Jacobs E, Audi S, Murphy C) J Appl Physiol (1985) 1994 Nov;77(5):2093-103 PMID: 7868421 SCOPUS ID: 2-s2.0-0027973109 11/01/1994       3 Citations
  • Reversible inhibition of urea exchange in rat hepatocytes. (Effros RM, Jacobs E, Hacker A, Ozker K, Murphy C) J Clin Invest 1993 Jun;91(6):2822-8 PMID: 8514890 PMCID: PMC443350 SCOPUS ID: 2-s2.0-0027272067 06/01/1993       25 Citations
  • pH-induced calcium transients in type II alveolar epithelial cells. (Gerboth GD, Effros RM, Roman RJ, Jacobs ER) Am J Physiol 1993 May;264(5 Pt 1):L448-57 PMID: 8498523 SCOPUS ID: 2-s2.0-0027174969 05/01/1993       21 Citations
  • Benign bone lesions simulating metastases on Tc-99m diphosphonate imaging. (Sweeney DC, Greenberg JS, McAfee JG, Jacobs ER) Clin Nucl Med 1992 Feb;17(2):134-6 PMID: 1563184 SCOPUS ID: 2-s2.0-0026515175 02/01/1992       2 Citations
  • Adult respiratory distress syndrome. Sequence and importance of development of multiple organ failure. The Prostaglandin E1 Study Group. (Bone RC, Balk R, Slotman G, Maunder R, Silverman H, Hyers TM, Kerstein MD) Chest 1992 Feb;101(2):320-6 PMID: 1735248 SCOPUS ID: 2-s2.0-0026570722 02/01/1992       112 Citations
  • Pulmonary normobaric oxygen toxicity (Lipchik RJ, Presberg KW, Jacobs ER) Problems in Critical Care 1992;6(3):375-393 SCOPUS ID: 2-s2.0-0026725914 01/01/1992    
  • Mechanisms of potassium channel block in rat alveolar epithelial cells. (Jacobs ER, DeCoursey TE) J Pharmacol Exp Ther 1990 Nov;255(2):459-72 PMID: 1700814 SCOPUS ID: 2-s2.0-0025222445 11/01/1990       45 Citations
  • Effects of prostaglandin E1 on oxygen delivery and consumption in patients with the adult respiratory distress syndrome. Results from the prostaglandin E1 multicenter trial. The Prostaglandin E1 Study Group. (Silverman HJ, Slotman G, Bone RC, Maunder R, Hyers TM, Kerstein MD, Ursprung JJ) Chest 1990 Aug;98(2):405-10 PMID: 2198140 SCOPUS ID: 2-s2.0-0025062099 08/01/1990       51 Citations
  • Comparison of vitamin E levels in plasma, bronchoalveolar lavage, and lung tissues of adult pulmonary patients. (Tangney CC, Stibolt TB Jr, Zheutlin L, Jacobs E, Hanley M) J Am Coll Nutr 1989 Jun;8(3):203-14 PMID: 2760352 SCOPUS ID: 2-s2.0-0024831417 06/01/1989       14 Citations
  • Ion channels in the metabolic regulation of respiratory cells. (Jacobs ER, DeCoursey TE) Clin Chest Med 1989 Mar;10(1):25-36 PMID: 2468439 SCOPUS ID: 2-s2.0-0024600088 03/01/1989       2 Citations
  • Potassium currents in rat type II alveolar epithelial cells. (DeCoursey TE, Jacobs ER, Silver MR) J Physiol 1988 Jan;395:487-505 PMID: 2457683 PMCID: PMC1192006 SCOPUS ID: 2-s2.0-0023852692 01/01/1988       50 Citations
  • Incidence of aspiration in tracheally intubated adults. (Elpern EH, Jacobs ER, Bone RC) Heart Lung 1987 Sep;16(5):527-31 PMID: 3115917 SCOPUS ID: 2-s2.0-0023247378 09/01/1987       99 Citations
  • Increased hemodynamic and survival with endotoxin and septic shock with ibuprofen treatment. (Bone RC, Jacobs ER, Wilson FJ Jr) Prog Clin Biol Res 1987;236A:327-32 PMID: 3303045 SCOPUS ID: 2-s2.0-0023064964 01/01/1987       6 Citations
  • C3A DES ARG and elastase-alpha 1-protease inhibitor levels in lavage fluid from patients with adult respiratory distress syndrome (Zheutlin LM, Thonar EJMA, Lemley-Gillespie S, Jacobs ER, Hanley ME, Balk RA, Bone RC) Journal of Critical Care June 1987;2(2):86-92 SCOPUS ID: 2-s2.0-0023177770 01/01/1987       2 Citations
  • Therapeutic implications of acute lung injury. (Jacobs ER, Bone RC) Crit Care Clin 1986 Jul;2(3):615-28 PMID: 3331566 SCOPUS ID: 2-s2.0-0022966575 07/01/1986       3 Citations
  • Clinical indicators in sepsis and septic adult respiratory distress syndrome. (Jacobs ER, Bone RC) Med Clin North Am 1986 Jul;70(4):921-32 PMID: 3520186 SCOPUS ID: 2-s2.0-0022517206 07/01/1986       24 Citations
  • Pseudomembranous colitis & antibiotics. (Goodpasture HC, Dolan PJ Jr, Jacobs ER, Meredith WT) Kans Med 1986 May;87(5):133, 146 PMID: 3712916 SCOPUS ID: 2-s2.0-0022720271 05/01/1986       7 Citations
  • Increased survival in bacteremic sheep treated with ibuprofen (Jacobs ER, Bone RC, Balk R, Wilson FJ) Journal of Critical Care 1986;1(3):142-149 SCOPUS ID: 2-s2.0-0023011558 01/01/1986       5 Citations
  • Plasma elastase levels in the adult respiratory distress syndrome (Zheutlin LM, Thonar EJMA, Jacobs ER, Hanley ME, Balk RA, Bone RC) Journal of Critical Care 1986;1(1):39-44 SCOPUS ID: 2-s2.0-0023022926 01/01/1986       17 Citations
  • Immunoglobulin G-induced single ionic channels in human alveolar macrophage membranes. (Nelson DJ, Jacobs ER, Tang JM, Zeller JM, Bone RC) J Clin Invest 1985 Aug;76(2):500-7 PMID: 2411759 PMCID: PMC423851 SCOPUS ID: 2-s2.0-0021982129 08/01/1985       28 Citations
  • Research on ibuprofen for sepsis and respiratory failure. (Bone RC, Jacobs ER) Am J Med 1984 Jul 13;77(1A):114-20 PMID: 6431806 SCOPUS ID: 2-s2.0-0021147078 07/13/1984       7 Citations
  • Protection of myocardial function during endotoxin shock by ibuprofen. (Soulsby ME, Jacobs ER, Perlmutter BH, Bone RC) Prostaglandins Leukot Med 1984 Mar;13(3):295-305 PMID: 6585848 SCOPUS ID: 2-s2.0-0021323198 03/01/1984       15 Citations
  • Mediators of septic lung injury. (Jacobs ER, Bone RC) Med Clin North Am 1983 May;67(3):701-15 PMID: 6302411 SCOPUS ID: 2-s2.0-0020538450 05/01/1983       18 Citations
  • Ibuprofen in canine endotoxin shock. (Jacobs ER, Soulsby ME, Bone RC, Wilson FJ Jr, Hiller FC) J Clin Invest 1982 Sep;70(3):536-41 PMID: 7107893 PMCID: PMC370254 09/01/1982    
  • The effect of steroids and thromboxane synthetase inhibitor on endotoxin shock (Balk RS, Jacobs ER, Bone RC) Chest 1982;82(2):234 SCOPUS ID: 2-s2.0-0020416425 01/01/1982    
  • Ibuprofen compared to naloxone in canine endotoxin shock (Jacobs E, Bone R, Soulsby M) American Review of Respiratory Disease 1982;125(4 II):92 SCOPUS ID: 2-s2.0-0019978788 01/01/1982       1 Citation
  • Naloxone blockade of endorphins in canine endotoxin shock (Jacobs ER, Bone RC, Wilson FJ, Hiller FC) Microcirculation 1982;2(1):19-27 SCOPUS ID: 2-s2.0-0020377078 01/01/1982       4 Citations
  • Protection of myocardial function during endotoxin shock by ibuprofen (Soulsby ME, Jacobs ER, Perlmutter BH, Bone RC) Federation Proceedings 1982;41(4) SCOPUS ID: 2-s2.0-0020064738 01/01/1982    
  • Naloxone reversal of hypotension: A clinical study (Bone R, Jacobs E, Wilson F, Hiller F) American Review of Respiratory Disease 1982;125(4 II):93 SCOPUS ID: 2-s2.0-0019950911 01/01/1982       3 Citations
  • Ibuprofen in canine endotoxin shock (Jacobs ER, Soulsby ME, Bone RC, Wilson FJ, Hiller FC) Journal of Clinical Investigation 1982;70(3):536-541 SCOPUS ID: 2-s2.0-0019969613 01/01/1982       100 Citations
  • Endorphins in endotoxin shock (Bone RC, Jacobs ER, Potter DM) Microcirculation 1981;1(3):285-295 SCOPUS ID: 2-s2.0-0019724978 01/01/1981       15 Citations
  • Why qualifications; school nurses (teachers of health and hygiene?). (JACOBS ER) Mon Bull Indiana State Board Health 1946 Sep;49(9):207 PMID: 20278086 SCOPUS ID: 2-s2.0-84872478994 09/01/1946    
    • Last update: 01/14/2023