Medical College of Wisconsin
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Emma M. Bonniwell

Emma M. Bonniwell profile photo picture

Postdoctoral Researcher

Institution: Medical College of Wisconsin
Department: Cell Biology Neurobiology and Anatomy

image of /images/ORCIDiD_icon16x16.png   https://orcid.org/0000-0001-5743-852X

Publications (8)

  • Discovery of Highly Selective 5-HT2A Agonists Using Structure-Guided Design. (Fenske TG, McKee JL, Cavalco NG, Schalk SS, Bonniwell EM, Lammers JC, Shacham N, Cuccurazzu B, Halberstadt AL, McCorvy JD) J Med Chem 2025 Oct 09;68(19):20619-20635 PMID: 40997862 PMCID: PMC12713736 SCOPUS ID: 2-s2.0-105018334639 09/26/2025    
  • Serotonin 5-HT2C Receptor Signaling Analysis Reveals Psychedelic Biased Agonism. (Bonniwell EM, Alabdali R, Hennessey JJ, McKee JL, Cavalco NG, Lammers JC, Moore EJ, Franchini L, Orlandi C, McCorvy JD) ACS Chem Neurosci 2025 Oct 01;16(19):3899-3914 PMID: 40944639 PMCID: PMC12629614 SCOPUS ID: 2-s2.0-105017796655 09/13/2025       4 Citations
  • Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential. (Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, Fannana T, Zauhar R, Halberstadt AL, McCorvy JD) Nat Commun 2023 Dec 15;14(1):8221 PMID: 38102107 PMCID: PMC10724237 SCOPUS ID: 2-s2.0-85179903706 12/16/2023       137 Citations
  • Beyond the 5-HT2A Receptor: Classic and Nonclassic Targets in Psychedelic Drug Action. (Cameron LP, Benetatos J, Lewis V, Bonniwell EM, Jaster AM, Moliner R, Castrén E, McCorvy JD, Palner M, Aguilar-Valles A) J Neurosci 2023 Nov 08;43(45):7472-7482 PMID: 37940583 PMCID: PMC10634557 SCOPUS ID: 2-s2.0-85176431720 11/09/2023       77 Citations
  • Psilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala. (Kelly TJ, Bonniwell EM, Mu L, Liu X, Hu Y, Friedman V, Yu H, Su W, McCorvy JD, Liu QS) Neuropsychopharmacology 2024 Apr;49(5):854-863 PMID: 37752222 PMCID: PMC10948882 SCOPUS ID: 2-s2.0-85172244117 09/27/2023       18 Citations
  • Identification of 5-HT2A Receptor Signaling Pathways Responsible for Psychedelic Potential. (Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, Fannana T, Zauhar R, Halberstadt AL, McCorvy JD) bioRxiv 2023 Jul 31 PMID: 37577474 PMCID: PMC10418054 08/14/2023    
  • A non-hallucinogenic LSD analog with therapeutic potential for mood disorders. (Lewis V, Bonniwell EM, Lanham JK, Ghaffari A, Sheshbaradaran H, Cao AB, Calkins MM, Bautista-Carro MA, Arsenault E, Telfer A, Taghavi-Abkuh FF, Malcolm NJ, El Sayegh F, Abizaid A, Schmid Y, Morton K, Halberstadt AL, Aguilar-Valles A, McCorvy JD) Cell Rep 2023 Mar 28;42(3):112203 PMID: 36884348 PMCID: PMC10112881 SCOPUS ID: 2-s2.0-85149448597 03/09/2023       114 Citations
  • Pharmacological Mechanism of the Non-hallucinogenic 5-HT2A Agonist Ariadne and Analogs. (Cunningham MJ, Bock HA, Serrano IC, Bechand B, Vidyadhara DJ, Bonniwell EM, Lankri D, Duggan P, Nazarova AL, Cao AB, Calkins MM, Khirsariya P, Hwu C, Katritch V, Chandra SS, McCorvy JD, Sames D) ACS Chem Neurosci 2023 Jan 04;14(1):119-135 PMID: 36521179 PMCID: PMC10147382 SCOPUS ID: 2-s2.0-85144247830 12/16/2022       55 Citations
    • Last update: 06/01/2026