Medical College of Wisconsin
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Gracious R. Ross

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Research Scientist II

Institution: Medical College of Wisconsin
Department: Cardiovascular Center

Publications (35)

  • Conquering Metabolic Syndrome: Navigating Pharmacological Avenues for Comprehensive Therapeutics. (Ross GR) J Pharmacol Exp Ther 2024 Jan 17;388(2):229-231 PMID: 38233228 SCOPUS ID: 2-s2.0-85182957277 01/18/2024    
  • Profibrotic COVID-19 subphenotype exhibits enhanced localized ER-dependent HSP47+ expression in cardiac myofibroblasts in situ. (Jacobs ER, Ross GR, Padilla N, Pan AY, Liegl M, Puzyrenko A, Lai S, Dai Q, Uche N, Rubenstein JC, North PE, Ibrahim EH, Sun Y, Felix JC, Rui H, Benjamin IJ) J Mol Cell Cardiol 2023 Dec;185:1-12 PMID: 37839656 PMCID: PMC11000691 SCOPUS ID: 2-s2.0-85174455933 10/16/2023    
  • Collagen-Specific HSP47+ Myofibroblasts and CD163+ Macrophages Identify Profibrotic Phenotypes in Deceased Hearts With SARS-CoV-2 Infections. (Puzyrenko A, Jacobs ER, Padilla N, Devine A, Aljadah M, Gantner BN, Pan AY, Lai S, Dai Q, Rubenstein JC, North PE, Simpson PM, Willoughby RE, O'Meara CC, Flinn MA, Lough JW, Ibrahim EH, Zheng Z, Sun Y, Felix J, Hunt BC, Ross G, Rui H, Benjamin IJ) J Am Heart Assoc 2023 Feb 21;12(4):e027990 PMID: 36789856 PMCID: PMC10111490 SCOPUS ID: 2-s2.0-85148479620 02/16/2023       2 Citations
  • Effects of Aging on Cardiac Oxidative Stress and Transcriptional Changes in Pathways of Reactive Oxygen Species Generation and Clearance. (Rizvi F, Preston CC, Emelyanova L, Yousufuddin M, Viqar M, Dakwar O, Ross GR, Faustino RS, Holmuhamedov EL, Jahangir A) J Am Heart Assoc 2021 Aug 17;10(16):e019948 PMID: 34369184 PMCID: PMC8475058 SCOPUS ID: 2-s2.0-85113262638 08/10/2021       32 Citations
  • Biphasic effect of metformin on human cardiac energetics. (Emelyanova L, Bai X, Yan Y, Bosnjak ZJ, Kress D, Warner C, Kroboth S, Rudic T, Kaushik S, Stoeckl E, Ross GR, Rizvi F, Tajik AJ, Jahangir A) Transl Res 2021 Mar;229:5-23 PMID: 33045408 PMCID: PMC10655614 SCOPUS ID: 2-s2.0-85095776755 10/13/2020       20 Citations
  • Noninvasive biomarker-based risk stratification for development of new onset atrial fibrillation after coronary artery bypass surgery. (Rizvi F, Mirza M, Olet S, Albrecht M, Edwards S, Emelyanova L, Kress D, Ross GR, Holmuhamedov E, Tajik AJ, Khandheria BK, Jahangir A) Int J Cardiol 2020 May 15;307:55-62 PMID: 31952855 PMCID: PMC8011128 SCOPUS ID: 2-s2.0-85077919161 01/19/2020       20 Citations
  • Impact of statins on cellular respiration and de-differentiation of myofibroblasts in human failing hearts. (Emelyanova L, Sra A, Schmuck EG, Raval AN, Downey FX, Jahangir A, Rizvi F, Ross GR) ESC Heart Fail 2019 Oct;6(5):1027-1040 PMID: 31520523 PMCID: PMC6816080 SCOPUS ID: 2-s2.0-85073790139 09/15/2019       17 Citations
  • Deletion of transcription factor AP-2α gene attenuates fibroblast differentiation into myofibroblast. (Ross GR, Edwards S, Warner C, Homar P, Downey FX, Emelyanova L, Rizvi F, Jahangir A) J Cell Mol Med 2019 Sep;23(9):6494-6498 PMID: 31339227 PMCID: PMC6714505 SCOPUS ID: 2-s2.0-85071324638 07/25/2019       4 Citations
  • Prolonged post-differentiation culture influences the expression and biophysics of Na+ and Ca2+ channels in induced pluripotent stem cell-derived ventricular-like cardiomyocytes. (Ross GR, Rizvi F, Emelyanova L, Tajik AJ, Jahangir A) Cell Tissue Res 2019 Oct;378(1):59-66 PMID: 31041505 SCOPUS ID: 2-s2.0-85065260404 05/02/2019       2 Citations
  • Simvastatin reduces TGF-β1-induced SMAD2/3-dependent human ventricular fibroblasts differentiation: Role of protein phosphatase activation. (Rizvi F, Siddiqui R, DeFranco A, Homar P, Emelyanova L, Holmuhamedov E, Ross G, Tajik AJ, Jahangir A) Int J Cardiol 2018 Nov 01;270:228-236 PMID: 30220377 PMCID: PMC6146406 SCOPUS ID: 2-s2.0-85049347827 09/18/2018       13 Citations
  • Aging-related increase in store-operated Ca2+ influx in human ventricular fibroblasts. (Mohis M, Edwards S, Ryan S, Rizvi F, Tajik AJ, Jahangir A, Ross GR) Am J Physiol Heart Circ Physiol 2018 Jul 01;315(1):H83-H91 PMID: 29985070 SCOPUS ID: 2-s2.0-85051237167 07/10/2018       11 Citations
  • Enhanced store-operated Ca2+ influx and ORAI1 expression in ventricular fibroblasts from human failing heart. (Ross GR, Bajwa T Jr, Edwards S, Emelyanova L, Rizvi F, Holmuhamedov EL, Werner P, Downey FX, Tajik AJ, Jahangir A) Biol Open 2017 Mar 15;6(3):326-332 PMID: 28126709 PMCID: PMC5374400 SCOPUS ID: 2-s2.0-85016302877 01/28/2017       41 Citations
  • Chamber-specific differences in human cardiac fibroblast proliferation and responsiveness toward simvastatin. (Rizvi F, DeFranco A, Siddiqui R, Negmadjanov U, Emelyanova L, Holmuhamedov A, Ross G, Shi Y, Holmuhamedov E, Kress D, Tajik AJ, Jahangir A) Am J Physiol Cell Physiol 2016 Aug 01;311(2):C330-9 PMID: 27335167 PMCID: PMC5129770 SCOPUS ID: 2-s2.0-84983605342 06/24/2016       12 Citations
  • Selective downregulation of mitochondrial electron transport chain activity and increased oxidative stress in human atrial fibrillation. (Emelyanova L, Ashary Z, Cosic M, Negmadjanov U, Ross G, Rizvi F, Olet S, Kress D, Sra J, Tajik AJ, Holmuhamedov EL, Shi Y, Jahangir A) Am J Physiol Heart Circ Physiol 2016 Jul 01;311(1):H54-63 PMID: 27199126 PMCID: PMC4967212 SCOPUS ID: 2-s2.0-84983770722 05/21/2016       44 Citations
  • TGF-β1-mediated differentiation of fibroblasts is associated with increased mitochondrial content and cellular respiration. (Negmadjanov U, Godic Z, Rizvi F, Emelyanova L, Ross G, Richards J, Holmuhamedov EL, Jahangir A) PLoS One 2015;10(4):e0123046 PMID: 25849590 PMCID: PMC4388650 SCOPUS ID: 2-s2.0-84927534750 04/08/2015       68 Citations
  • Increased PDE5 activity and decreased Rho kinase and PKC activities in colonic muscle from caveolin-1-/- mice impair the peristaltic reflex and propulsion. (Mahavadi S, Bhattacharya S, Kumar DP, Clay C, Ross G, Akbarali HI, Grider JR, Murthy KS) Am J Physiol Gastrointest Liver Physiol 2013 Dec;305(12):G964-74 PMID: 24157969 PMCID: PMC3882438 SCOPUS ID: 2-s2.0-84890369778 10/26/2013       8 Citations
  • Sepiapterin ameliorates chemically induced murine colitis and azoxymethane-induced colon cancer. (Cardnell RJ, Rabender CS, Ross GR, Guo C, Howlett EL, Alam A, Wang XY, Akbarali HI, Mikkelsen RB) J Pharmacol Exp Ther 2013 Oct;347(1):117-25 PMID: 23912334 PMCID: PMC3781406 SCOPUS ID: 2-s2.0-84884668589 08/06/2013       16 Citations
  • Evidence for the putative cannabinoid receptor (GPR55)-mediated inhibitory effects on intestinal contractility in mice. (Ross GR, Lichtman A, Dewey WL, Akbarali HI) Pharmacology 2012;90(1-2):55-65 PMID: 22759743 PMCID: PMC3548934 SCOPUS ID: 2-s2.0-84863112729 07/05/2012       28 Citations
  • Opioid-induced hypernociception is associated with hyperexcitability and altered tetrodotoxin-resistant Na+ channel function of dorsal root ganglia. (Ross GR, Gade AR, Dewey WL, Akbarali HI) Am J Physiol Cell Physiol 2012 Apr 15;302(8):C1152-61 PMID: 22189556 PMCID: PMC3330728 SCOPUS ID: 2-s2.0-84859783544 12/23/2011       22 Citations
  • The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract. (Kang M, Maguma HT, Smith TH, Ross GR, Dewey WL, Akbarali HI) J Pharmacol Exp Ther 2012 Mar;340(3):567-76 PMID: 22129596 PMCID: PMC3286318 SCOPUS ID: 2-s2.0-84857349362 12/02/2011       52 Citations
  • Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice. (Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH) J Pharmacol Exp Ther 2011 Oct;339(1):173-85 PMID: 21719468 PMCID: PMC3186294 SCOPUS ID: 2-s2.0-80053144160 07/02/2011       93 Citations
  • Colonic inflammation alters Src kinase-dependent gating properties of single Ca2+ channels via tyrosine nitration (American Journal of Physiology - Gastrointestinal and Liver Physiology (2010) 298 (G976-G984)) (Ross GR, Kang M, Akbarali HI) American Journal of Physiology - Gastrointestinal and Liver Physiology August 2010;299(2) SCOPUS ID: 2-s2.0-77955598025 08/01/2010    
  • Adrenomedullin relaxes rat uterine artery: mechanisms and influence of pregnancy and estradiol. (Ross GR, Yallampalli U, Gangula PR, Reed L, Sathishkumar K, Gao H, Chauhan M, Yallampalli C) Endocrinology 2010 Sep;151(9):4485-93 PMID: 20631002 PMCID: PMC2940500 SCOPUS ID: 2-s2.0-77956029482 07/16/2010       28 Citations
  • Ion channel remodeling in gastrointestinal inflammation. (Akbarali HI, G Hawkins E, Ross GR, Kang M) Neurogastroenterol Motil 2010 Oct;22(10):1045-55 PMID: 20618833 PMCID: PMC2939949 SCOPUS ID: 2-s2.0-77956333680 07/14/2010       34 Citations
  • Colonic inflammation alters Src kinase-dependent gating properties of single Ca2+ channels via tyrosine nitration. (Ross GR, Kang M, Akbarali HI) Am J Physiol Gastrointest Liver Physiol 2010 Jun;298(6):G976-84 PMID: 20378833 PMCID: PMC3061627 SCOPUS ID: 2-s2.0-77952717910 04/10/2010       13 Citations
  • The effect of tyrosine nitration of L-type Ca2+ channels on excitation-transcription coupling in colonic inflammation. (Kang M, Ross GR, Akbarali HI) Br J Pharmacol 2010 Mar;159(6):1226-35 PMID: 20128810 PMCID: PMC2848927 SCOPUS ID: 2-s2.0-77949386273 02/05/2010       18 Citations
  • Morphine tolerance in the mouse ileum and colon. (Ross GR, Gabra BH, Dewey WL, Akbarali HI) J Pharmacol Exp Ther 2008 Nov;327(2):561-72 PMID: 18682567 PMCID: PMC2574683 SCOPUS ID: 2-s2.0-54349120029 08/07/2008       68 Citations
  • COOH-terminal association of human smooth muscle calcium channel Ca(v)1.2b with Src kinase protein binding domains: effect of nitrotyrosylation. (Kang M, Ross GR, Akbarali HI) Am J Physiol Cell Physiol 2007 Dec;293(6):C1983-90 PMID: 17942635 SCOPUS ID: 2-s2.0-37149009997 10/19/2007       18 Citations
  • Cyclic AMP-independent CGRP8-37-sensitive receptors mediate adrenomedullin-induced decrease of CaCl2-contraction in pregnant rat mesenteric artery. (Ross GR, Yallampalli U, Yallampalli C) J Vasc Res 2008;45(1):33-44 PMID: 17898545 SCOPUS ID: 2-s2.0-37249073803 09/28/2007       4 Citations
  • Nitrotyrosylation of Ca2+ channels prevents c-Src kinase regulation of colonic smooth muscle contractility in experimental colitis. (Ross GR, Kang M, Shirwany N, Malykhina AP, Drozd M, Akbarali HI) J Pharmacol Exp Ther 2007 Sep;322(3):948-56 PMID: 17551092 SCOPUS ID: 2-s2.0-34548077816 06/07/2007       24 Citations
  • Adrenomedullin-2, a novel calcitonin/calcitonin-gene-related peptide family peptide, relaxes rat mesenteric artery: influence of pregnancy. (Chauhan M, Ross GR, Yallampalli U, Yallampalli C) Endocrinology 2007 Apr;148(4):1727-35 PMID: 17218418 SCOPUS ID: 2-s2.0-33947385791 01/16/2007       36 Citations
  • Vascular hyperresponsiveness to adrenomedullin during pregnancy is associated with increased generation of cyclic nucleotides in rat mesenteric artery. (Ross GR, Yallampalli C) Biol Reprod 2007 Jan;76(1):118-23 PMID: 17050860 SCOPUS ID: 2-s2.0-33845737755 10/20/2006       15 Citations
  • Relative contribution of intracellular and extracellular Ca2+ to alpha2-adrenoceptor-mediated contractions of ovine pulmonary artery. (Sathishkumar K, Ross GR, Prakash VR, Mishra SK) Pharmacol Res 2006 Sep;54(3):219-25 PMID: 16787748 SCOPUS ID: 2-s2.0-33746345893 06/22/2006       1 Citation
  • Endothelium-independent relaxation by adrenomedullin in pregnant rat mesenteric artery: role of cAMP-dependent protein kinase A and calcium-activated potassium channels. (Ross GR, Yallampalli C) J Pharmacol Exp Ther 2006 Jun;317(3):1269-75 PMID: 16551834 SCOPUS ID: 2-s2.0-33646771751 03/23/2006       27 Citations
  • Female sex steroids increase adrenomedullin-induced vasodilation by increasing the expression of adrenomedullin2 receptor components in rat mesenteric artery. (Ross GR, Chauhan M, Gangula PR, Reed L, Thota C, Yallampalli C) Endocrinology 2006 Jan;147(1):389-96 PMID: 16210373 SCOPUS ID: 2-s2.0-29344436484 10/08/2005       19 Citations
    • Last update: 02/15/2024