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Hallgeir Rui MD, PhD

Vice Chair, Professor

Institution: Medical College of Wisconsin
Department: Pathology
Division: Administration

image of /images/ORCIDiD_icon16x16.png https://orcid.org/0000-0002-8778-261X

Member of the Cancer Center
Member of the Cardiovascular Center
Member of the Center for Disease Prevention Research (CDPR)
Member of the Center for Immunology

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Publications (202)

Tumor suppressive and immune-stimulating roles of cholesterol 25-hydroxylase in pancreatic cancer cells. (McBrearty N, Cho C, Chen J, Zahedi F, Peck AR, Radaelli E, Assenmacher CA, Pavlak C, Devine A, Yu P, Lu Z, Zhang H, Li J, Pitarresi JR, Astsaturov I, Cukierman E, Rustgi AK, Stanger BZ, Rui H, Fuchs SY) Mol Cancer Res 2022 Nov 15 PMID: 36378658 11/16/2022

Breast Cancer and Prolactin - New Mechanisms and Models. (Clevenger CV, Rui H) Endocrinology 2022 Oct 01;163(10) PMID: 35922139 PMCID: PMC9419691 SCOPUS ID: 2-s2.0-85137126932 08/04/2022

Sustained Inflammation of Breast Tumors after Needle Biopsy. (McCarty C, Yi M, Sous S, Leslie M, Tariq E, Dondapati P, Kameyama H, Nuguri S, Hills N, Wilkerson M, Davis R, Mesiya S, Rui H, Chervoneva I, Zhang R, Tanaka T) Pathobiology 2022 Jun 01:1-9 PMID: 35649384 SCOPUS ID: 2-s2.0-85131290013 06/02/2022

Spatial Metrics of Interaction between CD163-Positive Macrophages and Cancer Cells and Progression-Free Survival in Chemo-Treated Breast Cancer (Maisel BA, Yi M, Peck AR, Sun Y, Hooke JA, Kovatich AJ, Shriver CD, Hu H, Nevalainen MT, Tanaka T, Simone N, Wang LL, Rui H, Chervoneva I) Cancers January-2 2022;14(2) SCOPUS ID: 2-s2.0-85122409008 01/01/2022 2 Citations

Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells (Rädler PD, Wehde BL, Triplett AA, Shrestha H, Shepherd JH, Pfefferle AD, Rui H, Cardiff RD, Perou CM, Wagner KU) Nature Communications 1 December 2021;12(1) SCOPUS ID: 2-s2.0-85108162441 12/01/2021 13 Citations

Cytotoxic CD8-positive T-lymphocyte infiltration in the lungs as a histological pattern of SARS-CoV-2 pneumonitis. (Puzyrenko A, Felix JC, Ledeboer NA, Sun Y, Rui H, Sheinin Y) Pathology 2022 Jun;54(4):404-408 PMID: 34836647 PMCID: PMC8572726 SCOPUS ID: 2-s2.0-85119915379 11/28/2021

RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2021 Nov 02;37(5):109934 PMID: 34731628 PMCID: PMC8675433 SCOPUS ID: 2-s2.0-85118477211 11/04/2021 11 Citations

NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers. (Sun Y, Yang N, Utama FE, Udhane SS, Zhang J, Peck AR, Yanac A, Duffey K, Langenheim JF, Udhane V, Xia G, Peterson JF, Jorns JM, Nevalainen MT, Rouet R, Schofield P, Christ D, Ormandy CJ, Rosenberg AL, Chervoneva I, Tsaih SW, Flister MJ, Fuchs SY, Wagner KU, Rui H) Sci Adv 2021 Sep 17;7(38):eabc8145 PMID: 34524841 PMCID: PMC8443188 SCOPUS ID: 2-s2.0-85115168052 09/16/2021 3 Citations

Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies. (Puzyrenko A, Jacobs ER, Sun Y, Felix JC, Sheinin Y, Ge L, Lai S, Dai Q, Gantner BN, Nanchal R, North PE, Simpson PM, Rui H, Benjamin IJ) Cell Stress Chaperones 2021 Sep;26(5):859-868 PMID: 34382151 PMCID: PMC8357488 SCOPUS ID: 2-s2.0-85112285201 08/13/2021 5 Citations

Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. (Geethadevi A, Nair A, Parashar D, Ku Z, Xiong W, Deng H, Li Y, George J, McAllister DM, Sun Y, Kadamberi IP, Gupta P, Dwinell MB, Bradley WH, Rader JS, Rui H, Schwabe RF, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P) Cancer Res 2021 Oct 15;81(20):5336-5352 PMID: 34380633 PMCID: PMC8530981 SCOPUS ID: 2-s2.0-85116424540 08/13/2021 11 Citations

Theory, methods, and operational results of the Young Women's Health History Study: a study of young-onset breast cancer incidence in Black and White women. (Velie EM, Marcus LR, Pathak DR, Hamilton AS, DiGaetano R, Klinger R, Gollapudi B, Houang R, Carnegie N, Olson LK, Allen A, Zhang Z, Modjesk D, Norman G, Lucas DR, Gupta S, Rui H, Schwartz K) Cancer Causes Control 2021 Oct;32(10):1129-1148 PMID: 34292440 PMCID: PMC8416838 SCOPUS ID: 2-s2.0-85111106933 07/23/2021 1 Citation

Sensitive and Specific Immunohistochemistry Protocol for Nucleocapsid Protein from All Common SARS-CoV-2 Virus Strains in Formalin-Fixed, Paraffin Embedded Tissues. (Sun Y, Ge L, Udhane SS, Langenheim JF, Rau MJ, Patton MD, Gallan AJ, Felix JC, Rui H) Methods Protoc 2021 Jul 10;4(3) PMID: 34287344 PMCID: PMC8293419 SCOPUS ID: 2-s2.0-85111011758 07/22/2021 4 Citations

Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells. (Rädler PD, Wehde BL, Triplett AA, Shrestha H, Shepherd JH, Pfefferle AD, Rui H, Cardiff RD, Perou CM, Wagner KU) Nat Commun 2021 Jun 18;12(1):3742 PMID: 34145248 PMCID: PMC8213728 SCOPUS ID: 2-s2.0-85108162441 06/20/2021 13 Citations

Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies. (Lu Z, Ortiz A, Verginadis II, Peck AR, Zahedi F, Cho C, Yu P, DeRita RM, Zhang H, Kubanoff R, Sun Y, Yaspan AT, Krespan E, Beiting DP, Radaelli E, Ryeom SW, Diehl JA, Rui H, Koumenis C, Fuchs SY) J Clin Invest 2021 May 17;131(10) PMID: 33998600 PMCID: PMC8121529 SCOPUS ID: 2-s2.0-85106569543 05/18/2021 4 Citations

Diffuse interstitial pneumonia-like/macrophage activation syndrome-like changes in patients with COVID-19 correlate with length of illness. (Felix JC, Sheinin YM, Suster D, Ronen N, Ratiani M, Vanden Heuvel T, Winge E, Patton MD, Rau MJ, Ge L, Sun Y, Udhane SS, Langenheim JF, Rui H) Ann Diagn Pathol 2021 Aug;53:151744 PMID: 33991784 PMCID: PMC8053602 SCOPUS ID: 2-s2.0-85105597450 05/16/2021 2 Citations

Prolonged Time from Diagnosis to Breast-Conserving Surgery is Associated with Upstaging in Hormone Receptor-Positive Invasive Ductal Breast Carcinoma. (Hills N, Leslie M, Davis R, Crowell M, Kameyama H, Rui H, Chervoneva I, Dooley W, Tanaka T) Ann Surg Oncol 2021 Oct;28(11):5895-5905 PMID: 33748899 PMCID: PMC7982278 SCOPUS ID: 2-s2.0-85102190144 03/23/2021 4 Citations

Leveraging Antiprogestins in the Treatment of Metastatic Breast Cancer. (Kamaraju S, Fowler AM, Weil E, Wisinski KB, Truong TH, Lehr M, Chaudhary LN, Cheng YC, Chitambar CR, Rui H, Yee D, Lange C) Endocrinology 2021 Aug 01;162(8) PMID: 33735382 SCOPUS ID: 2-s2.0-85111784651 03/19/2021 3 Citations

Acute SARS-CoV-2 pneumonitis with cytotoxic CD8 positive T-lymphocytes: Case report and review of the literature. (Puzyrenko A, Felix JC, Sun Y, Rui H, Sheinin Y) Pathol Res Pract 2021 Apr;220:153380 PMID: 33676105 PMCID: PMC7883708 SCOPUS ID: 2-s2.0-85101878778 03/07/2021 5 Citations

ASO Author Reflections: Does Prompt Breast-Conserving Surgery Matter? (Hills N, Leslie M, Davis R, Crowell M, Kamemyama H, Rui H, Chervoneva I, Dooley W, Tanaka T) Ann Surg Oncol 2021 Oct;28(11):5906 PMID: 33666812 SCOPUS ID: 2-s2.0-85102168364 03/06/2021

Quantification of spatial tumor heterogeneity in immunohistochemistry staining images. (Chervoneva I, Peck AR, Yi M, Freydin B, Rui H) Bioinformatics 2021 Jun 16;37(10):1452-1460 PMID: 33275142 PMCID: PMC8208754 SCOPUS ID: 2-s2.0-85108385952 12/05/2020 3 Citations

The membrane-associated form of cyclin D1 enhances cellular invasion. (Chen K, Jiao X, Ashton A, Di Rocco A, Pestell TG, Sun Y, Zhao J, Casimiro MC, Li Z, Lisanti MP, McCue PA, Shen D, Achilefu S, Rui H, Pestell RG) Oncogenesis 2020 Sep 18;9(9):83 PMID: 32948740 PMCID: PMC7501870 SCOPUS ID: 2-s2.0-85091177817 09/20/2020 7 Citations

Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis. (Cho C, Mukherjee R, Peck AR, Sun Y, McBrearty N, Katlinski KV, Gui J, Govindaraju PK, Puré E, Rui H, Fuchs SY) Oncogene 2020 Sep;39(38):6129-6137 PMID: 32807917 PMCID: PMC7502515 SCOPUS ID: 2-s2.0-85089539324 08/19/2020 11 Citations

Individualized multi-omic pathway deviation scores using multiple factor analysis. (Rau A, Manansala R, Flister MJ, Rui H, Jaffrézic F, Laloë D, Auer PL) Biostatistics 2022 Apr 13;23(2):362-379 PMID: 32766691 PMCID: PMC9074877 SCOPUS ID: 2-s2.0-85112009803 08/09/2020 1 Citation

Malignant cell-specific pro-tumorigenic role of type I interferon receptor in breast cancers. (Odnokoz O, Yu P, Peck AR, Sun Y, Kovatich AJ, Hooke JA, Hu H, Mitchell EP, Rui H, Fuchs SY) Cancer Biol Ther 2020 Jul 02;21(7):629-636 PMID: 32378445 PMCID: PMC7515508 SCOPUS ID: 2-s2.0-85084376942 05/08/2020 4 Citations

Acquired Immunity Is Not Essential for Radiation-Induced Heart Dysfunction but Exerts a Complex Impact on Injury. (Schlaak RA, Frei A, Fish BL, Harmann L, Gasperetti T, Pipke JL, Sun Y, Rui H, Flister MJ, Gantner BN, Bergom C) Cancers (Basel) 2020 Apr 16;12(4) PMID: 32316187 PMCID: PMC7226421 SCOPUS ID: 2-s2.0-85083724334 04/23/2020 4 Citations

Functional Blockade of E-Selectin in Tumor-Associated Vessels Enhances Anti-Tumor Effect of Doxorubicin in Breast Cancer. (Morita Y, Leslie M, Kameyama H, Lokesh GLR, Ichimura N, Davis R, Hills N, Hasan N, Zhang R, Kondo Y, Gorenstein DG, Volk DE, Chervoneva I, Rui H, Tanaka T) Cancers (Basel) 2020 Mar 19;12(3) PMID: 32204492 PMCID: PMC7140021 SCOPUS ID: 2-s2.0-85082476666 03/25/2020 5 Citations

Mapping Mammary Tumor Traits in the Rat. (Flister MJ, Joshi A, Bergom C, Rui H) Methods Mol Biol 2019;2018:249-267 PMID: 31228161 PMCID: PMC9272588 SCOPUS ID: 2-s2.0-85068143262 06/23/2019 1 Citation

The p52 isoform of SHC1 is a key driver of breast cancer initiation. (Wright KD, Miller BS, El-Meanawy S, Tsaih SW, Banerjee A, Geurts AM, Sheinin Y, Sun Y, Kalyanaraman B, Rui H, Flister MJ, Sorokin A) Breast Cancer Res 2019 Jun 15;21(1):74 PMID: 31202267 PMCID: PMC6570928 SCOPUS ID: 2-s2.0-85067234098 06/17/2019 19 Citations

Neuronatin is a modifier of estrogen receptor-positive breast cancer incidence and outcome. (Plasterer C, Tsaih SW, Peck AR, Chervoneva I, O'Meara C, Sun Y, Lemke A, Murphy D, Smith J, Ran S, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Mitchell EP, Bergom C, Joshi A, Auer P, Prokop J, Rui H, Flister MJ) Breast Cancer Res Treat 2019 Aug;177(1):77-91 PMID: 31165373 SCOPUS ID: 2-s2.0-85066986189 06/06/2019

Identification of a Rat Mammary Tumor Risk Locus That Is Syntenic with the Commonly Amplified 8q12.1 and 8q22.1 Regions in Human Breast Cancer Patients. (Plasterer C, Tsaih SW, Lemke A, Schilling R, Dwinell M, Rau A, Auer P, Rui H, Flister MJ) G3 (Bethesda) 2019 May 07;9(5):1739-1743 PMID: 30914425 PMCID: PMC6505137 SCOPUS ID: 2-s2.0-85065792535 03/28/2019 4 Citations

Mapping genetic modifiers of radiation-induced cardiotoxicity to rat chromosome 3. (Schlaak RA, Frei A, Schottstaedt AM, Tsaih SW, Fish BL, Harmann L, Liu Q, Gasperetti T, Medhora M, North PE, Strande JL, Sun Y, Rui H, Flister MJ, Bergom C) Am J Physiol Heart Circ Physiol 2019 Jun 01;316(6):H1267-H1280 PMID: 30848680 PMCID: PMC6620678 SCOPUS ID: 2-s2.0-85066837925 03/09/2019 22 Citations

An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles. (Ortiz A, Gui J, Zahedi F, Yu P, Cho C, Bhattacharya S, Carbone CJ, Yu Q, Katlinski KV, Katlinskaya YV, Handa S, Haas V, Volk SW, Brice AK, Wals K, Matheson NJ, Antrobus R, Ludwig S, Whiteside TL, Sander C, Tarhini AA, Kirkwood JM, Lehner PJ, Guo W, Rui H, Minn AJ, Koumenis C, Diehl JA, Fuchs SY) Cancer Cell 2019 Jan 14;35(1):33-45.e6 PMID: 30645975 PMCID: PMC6336114 SCOPUS ID: 2-s2.0-85058438732 01/16/2019 82 Citations

Exploring drivers of gene expression in the Cancer Genome Atlas. (Rau A, Flister M, Rui H, Auer PL) Bioinformatics 2019 Jan 01;35(1):62-68 PMID: 30561551 PMCID: PMC6298045 SCOPUS ID: 2-s2.0-85058741070 12/19/2018 17 Citations

Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells. (Gennaro VJ, Stanek TJ, Peck AR, Sun Y, Wang F, Qie S, Knudsen KE, Rui H, Butt T, Diehl JA, McMahon SB) Proc Natl Acad Sci U S A 2018 Oct 02;115(40):E9298-E9307 PMID: 30224477 PMCID: PMC6176615 SCOPUS ID: 2-s2.0-85054360749 09/19/2018 62 Citations

Loss of Nuclear Localized Parathyroid Hormone-Related Protein in Primary Breast Cancer Predicts Poor Clinical Outcome and Correlates with Suppressed Stat5 Signaling. (Tran TH, Utama FE, Sato T, Peck AR, Langenheim JF, Udhane SS, Sun Y, Liu C, Girondo MA, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Palazzo JP, Bibbo M, Auer PW, Flister MJ, Hyslop T, Mitchell EP, Chervoneva I, Rui H) Clin Cancer Res 2018 Dec 15;24(24):6355-6366 PMID: 30097435 SCOPUS ID: 2-s2.0-85058487046 08/12/2018 6 Citations

CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion. (Jiao X, Velasco-Velázquez MA, Wang M, Li Z, Rui H, Peck AR, Korkola JE, Chen X, Xu S, DuHadaway JB, Guerrero-Rodriguez S, Addya S, Sicoli D, Mu Z, Zhang G, Stucky A, Zhang X, Cristofanilli M, Fatatis A, Gray JW, Zhong JF, Prendergast GC, Pestell RG) Cancer Res 2018 Apr 01;78(7):1657-1671 PMID: 29358169 PMCID: PMC6331183 SCOPUS ID: 2-s2.0-85047155981 01/24/2018 71 Citations

Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth. (Pestell TG, Jiao X, Kumar M, Peck AR, Prisco M, Deng S, Li Z, Ertel A, Casimiro MC, Ju X, Di Rocco A, Di Sante G, Katiyar S, Shupp A, Lisanti MP, Jain P, Wu K, Rui H, Hooper DC, Yu Z, Goldman AR, Speicher DW, Laury-Kleintop L, Pestell RG) Oncotarget 2017 Oct 10;8(47):81754-81775 PMID: 29137220 PMCID: PMC5669846 SCOPUS ID: 2-s2.0-85030853948 11/16/2017 23 Citations

Comparative Survival Analysis of Invasive Breast Cancer Patients Treated by a U.S. Military Medical Center and Matched Patients From the U.S. General Population. (Ru Y, Liu J, Fantacone-Campbell JL, Zhu K, Kovatich AJ, Hooke JA, Kvecher L, Deyarmin B, Kovatich AW, Cammarata F, Hueman MT, Rui H, Mural RJ, Shriver CD, Hu H) Mil Med 2017 Nov;182(11):e1851-e1858 PMID: 29087852 SCOPUS ID: 2-s2.0-85032743323 11/01/2017 6 Citations

SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression. (Gonyo P, Bergom C, Brandt AC, Tsaih SW, Sun Y, Bigley TM, Lorimer EL, Terhune SS, Rui H, Flister MJ, Long RM, Williams CL) Oncogene 2017 Dec 14;36(50):6873-6883 PMID: 28806394 PMCID: PMC5730474 SCOPUS ID: 2-s2.0-85038242723 08/15/2017 10 Citations

Pathologic evaluation of tumor-associated macrophage density and vessel inflammation in invasive breast carcinomas. (Morita Y, Zhang R, Leslie M, Adhikari S, Hasan N, Chervoneva I, Rui H, Tanaka T) Oncol Lett 2017 Aug;14(2):2111-2118 PMID: 28789438 PMCID: PMC5530034 SCOPUS ID: 2-s2.0-85021769307 08/10/2017 21 Citations

Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment. (Katlinski KV, Gui J, Katlinskaya YV, Ortiz A, Chakraborty R, Bhattacharya S, Carbone CJ, Beiting DP, Girondo MA, Peck AR, Puré E, Chatterji P, Rustgi AK, Diehl JA, Koumenis C, Rui H, Fuchs SY) Cancer Cell 2017 Feb 13;31(2):194-207 PMID: 28196594 PMCID: PMC5313042 SCOPUS ID: 2-s2.0-85012931658 02/16/2017 141 Citations

Serum levels 01 tne immunomodulatory protein, the progesterone induced blocking factor (PIBF) which is found in high levels during pregnancy is not higher in women with progesterone (P) receptor (R) positive vs. Negative breast cancer (Check JH, Rosenberg A, Check DL, DiAntonio A, Rui H, Cohen R, DiAntonio G) Clinical and Experimental Obstetrics and Gynecology 2017;44(2):187-189 SCOPUS ID: 2-s2.0-85017170052 01/01/2017 6 Citations

E-selectin Targeting PEGylated-thioaptamer Prevents Breast Cancer Metastases. (Morita Y, Kamal M, Kang SA, Zhang R, Lokesh GL, Thiviyanathan V, Hasan N, Woo S, Zhao D, Leslie M, Suh S, Razaq W, Rui H, Gorenstein DG, Volk DE, Tanaka T) Mol Ther Nucleic Acids 2016 Dec 13;5(12):e399 PMID: 27959340 SCOPUS ID: 2-s2.0-85015659915 12/14/2016 21 Citations

Therapeutic Elimination of the Type 1 Interferon Receptor for Treating Psoriatic Skin Inflammation. (Gui J, Gober M, Yang X, Katlinski KV, Marshall CM, Sharma M, Werth VP, Baker DP, Rui H, Seykora JT, Fuchs SY) J Invest Dermatol 2016 Oct;136(10):1990-2002 PMID: 27369778 PMCID: PMC5035634 SCOPUS ID: 2-s2.0-84996743478 07/03/2016 21 Citations

Erratum to: The effect of soluble E-selectin on tumor progression and metastasis. (Kang SA, Blache CA, Bajana S, Hasan N, Kamal M, Morita Y, Gupta V, Tsolmon B, Suh KS, Gorenstein DG, Razaq W, Rui H, Tanaka T) BMC Cancer 2016 Jun 28;16(1):370 PMID: 27353033 PMCID: PMC4926296 SCOPUS ID: 2-s2.0-84976469900 06/30/2016 1 Citation

Validation of tumor protein marker quantification by two independent automated immunofluorescence image analysis platforms. (Peck AR, Girondo MA, Liu C, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Mitchell EP, Freydin B, Hyslop T, Chervoneva I, Rui H) Mod Pathol 2016 Oct;29(10):1143-54 PMID: 27312066 PMCID: PMC5047958 SCOPUS ID: 2-s2.0-84975132610 06/18/2016 17 Citations

The effect of soluble E-selectin on tumor progression and metastasis. (Kang SA, Blache CA, Bajana S, Hasan N, Kamal M, Morita Y, Gupta V, Tsolmon B, Suh KS, Gorenstein DG, Razaq W, Rui H, Tanaka T) BMC Cancer 2016 May 24;16:331 PMID: 27220365 PMCID: PMC4879723 SCOPUS ID: 2-s2.0-84969921275 05/26/2016 29 Citations

Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. (Katlinskaya YV, Katlinski KV, Yu Q, Ortiz A, Beiting DP, Brice A, Davar D, Sanders C, Kirkwood JM, Rui H, Xu X, Koumenis C, Diehl JA, Fuchs SY) Cell Rep 2016 Apr 05;15(1):171-180 PMID: 27052162 PMCID: PMC4826807 SCOPUS ID: 2-s2.0-84963545903 04/08/2016 66 Citations

The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells. (Blanco FF, Jimbo M, Wulfkuhle J, Gallagher I, Deng J, Enyenihi L, Meisner-Kober N, Londin E, Rigoutsos I, Sawicki JA, Risbud MV, Witkiewicz AK, McCue PA, Jiang W, Rui H, Yeo CJ, Petricoin E, Winter JM, Brody JR) Oncogene 2016 May;35(19):2529-41 PMID: 26387536 PMCID: PMC6818728 SCOPUS ID: 2-s2.0-84968747402 09/22/2015 73 Citations

Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer. (Talati PG, Gu L, Ellsworth EM, Girondo MA, Trerotola M, Hoang DT, Leiby B, Dagvadorj A, McCue PA, Lallas CD, Trabulsi EJ, Gomella L, Aplin AE, Languino L, Fatatis A, Rui H, Nevalainen MT) Am J Pathol 2015 Sep;185(9):2505-22 PMID: 26362718 PMCID: PMC4597281 SCOPUS ID: 2-s2.0-84941053082 09/13/2015 49 Citations

Positive Association of Fibroadenomatoid Change with HER2-Negative Invasive Breast Cancer: A Co-Occurrence Study. (Chen Y, Bekhash A, Kovatich AJ, Hooke JA, Liu J, Kvecher L, Fantacone-Campbell JL, Mitchell EP, Rui H, Mural RJ, Shriver CD, Hu H) PLoS One 2015;10(6):e0129500 PMID: 26098961 PMCID: PMC4476726 SCOPUS ID: 2-s2.0-84939154220 06/23/2015 6 Citations

Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism. (Goodman CR, Sato T, Peck AR, Girondo MA, Yang N, Liu C, Yanac AF, Kovatich AJ, Hooke JA, Shriver CD, Mitchell EP, Hyslop T, Rui H) Oncogene 2016 Mar 17;35(11):1373-85 PMID: 26096934 PMCID: PMC4800289 SCOPUS ID: 2-s2.0-84932182008 06/23/2015 22 Citations

Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice. (Kang SA, Tsolmon B, Mann AP, Zheng W, Zhao L, Zhao YD, Volk DE, Lokesh GL, Morris L, Gupta V, Razaq W, Rui H, Suh KS, Gorenstein DG, Tanaka T) Toxicol Appl Pharmacol 2015 Aug 15;287(1):86-92 PMID: 26048585 PMCID: PMC4966538 SCOPUS ID: 2-s2.0-84935867738 06/07/2015 12 Citations

Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia. (Liao Z, Gu L, Vergalli J, Mariani SA, De Dominici M, Lokareddy RK, Dagvadorj A, Purushottamachar P, McCue PA, Trabulsi E, Lallas CD, Gupta S, Ellsworth E, Blackmon S, Ertel A, Fortina P, Leiby B, Xia G, Rui H, Hoang DT, Gomella LG, Cingolani G, Njar V, Pattabiraman N, Calabretta B, Nevalainen MT) Mol Cancer Ther 2015 Aug;14(8):1777-93 PMID: 26026053 PMCID: PMC4547362 SCOPUS ID: 2-s2.0-84942118590 05/31/2015 40 Citations

Blocking the adhesion cascade at the premetastatic niche for prevention of breast cancer metastasis. (Kang SA, Hasan N, Mann AP, Zheng W, Zhao L, Morris L, Zhu W, Zhao YD, Suh KS, Dooley WC, Volk D, Gorenstein DG, Cristofanilli M, Rui H, Tanaka T) Mol Ther 2015 Jun;23(6):1044-1054 PMID: 25815697 PMCID: PMC4817749 SCOPUS ID: 2-s2.0-84930178523 03/31/2015 37 Citations

The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer. (Wilson C, Lin JE, Li P, Snook AE, Gong J, Sato T, Liu C, Girondo MA, Rui H, Hyslop T, Waldman SA) Cancer Epidemiol Biomarkers Prev 2014 Nov;23(11):2328-37 PMID: 25304930 PMCID: PMC4221461 SCOPUS ID: 2-s2.0-84920145022 10/12/2014 45 Citations

Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury. (Bhattacharya S, Katlinski KV, Reichert M, Takano S, Brice A, Zhao B, Yu Q, Zheng H, Carbone CJ, Katlinskaya YV, Leu NA, McCorkell KA, Srinivasan S, Girondo M, Rui H, May MJ, Avadhani NG, Rustgi AK, Fuchs SY) EMBO Mol Med 2014 Mar;6(3):384-97 PMID: 24480543 PMCID: PMC3958312 SCOPUS ID: 2-s2.0-84896722537 02/01/2014 46 Citations

Expression of insulin-like growth factor-1 receptor in metastatic uveal melanoma and implications for potential autocrine and paracrine tumor cell growth. (Yoshida M, Selvan S, McCue PA, DeAngelis T, Baserga R, Fujii A, Rui H, Mastrangelo MJ, Sato T) Pigment Cell Melanoma Res 2014 Mar;27(2):297-308 PMID: 24354797 SCOPUS ID: 2-s2.0-84894085123 12/21/2013 34 Citations

NADPH oxidase subunit p22(phox)-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer. (Li Q, Fu GB, Zheng JT, He J, Niu XB, Chen QD, Yin Y, Qian X, Xu Q, Wang M, Sun AF, Shu Y, Rui H, Liu LZ, Jiang BH) Biochim Biophys Acta 2013 Dec;1833(12):3375-3385 PMID: 24113386 SCOPUS ID: 2-s2.0-84886843534 10/12/2013 36 Citations

Prolactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment. (Yang N, Liu C, Peck AR, Girondo MA, Yanac AF, Tran TH, Utama FE, Tanaka T, Freydin B, Chervoneva I, Hyslop T, Kovatich AJ, Hooke JA, Shriver CD, Rui H) Breast Cancer Res 2013;15(5):R73 PMID: 24004716 PMCID: PMC3978581 SCOPUS ID: 2-s2.0-84883283477 09/06/2013 15 Citations

Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. (Chen K, Wu K, Gormley M, Ertel A, Wang J, Zhang W, Zhou J, Disante G, Li Z, Rui H, Quong AA, McMahon SB, Deng H, Lisanti MP, Wang C, Pestell RG) Oncotarget 2013 Jun;4(6):923-35 PMID: 23798621 PMCID: PMC3757249 SCOPUS ID: 2-s2.0-84880830761 06/27/2013 22 Citations

Global profiling of prolactin-modulated transcripts in breast cancer in vivo. (Sato T, Tran TH, Peck AR, Liu C, Ertel A, Lin J, Neilson LM, Rui H) Mol Cancer 2013 Jun 12;12:59 PMID: 23758962 PMCID: PMC3691730 SCOPUS ID: 2-s2.0-84878818575 06/14/2013 26 Citations

Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expression. (Sato T, Tran TH, Peck AR, Girondo MA, Liu C, Goodman CR, Neilson LM, Freydin B, Chervoneva I, Hyslop T, Kovatich AJ, Hooke JA, Shriver CD, Fuchs SY, Rui H) Oncogene 2014 Apr 24;33(17):2215-24 PMID: 23708665 PMCID: PMC3913798 SCOPUS ID: 2-s2.0-84899629949 05/28/2013 34 Citations

STAT5A/B gene locus undergoes amplification during human prostate cancer progression. (Haddad BR, Gu L, Mirtti T, Dagvadorj A, Vogiatzi P, Hoang DT, Bajaj R, Leiby B, Ellsworth E, Blackmon S, Ruiz C, Curtis M, Fortina P, Ertel A, Liu C, Rui H, Visakorpi T, Bubendorf L, Lallas CD, Trabulsi EJ, McCue P, Gomella L, Nevalainen MT) Am J Pathol 2013 Jun;182(6):2264-75 PMID: 23660011 PMCID: PMC3668029 SCOPUS ID: 2-s2.0-84878221509 05/11/2013 40 Citations

Dachshund binds p53 to block the growth of lung adenocarcinoma cells. (Chen K, Wu K, Cai S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, Wang C, McMahon SB, Pestell RG) Cancer Res 2013 Jun 01;73(11):3262-74 PMID: 23492369 PMCID: PMC3674204 SCOPUS ID: 2-s2.0-84878553762 03/16/2013 51 Citations

Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer. (Lin WC, Rajbhandari N, Liu C, Sakamoto K, Zhang Q, Triplett AA, Batra SK, Opavsky R, Felsher DW, DiMaio DJ, Hollingsworth MA, Morris JP 4th, Hebrok M, Witkiewicz AK, Brody JR, Rui H, Wagner KU) Cancer Res 2013 Mar 15;73(6):1821-30 PMID: 23467612 PMCID: PMC3602120 SCOPUS ID: 2-s2.0-84875425951 03/08/2013 54 Citations

Population and target considerations for triple-negative breast cancer clinical trials. (Hyslop T, Michael Y, Avery T, Rui H) Biomark Med 2013 Feb;7(1):11-21 PMID: 23387481 PMCID: PMC3677035 SCOPUS ID: 2-s2.0-84873442332 02/08/2013 12 Citations

Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer. (Myklebust MP, Li Z, Tran TH, Rui H, Knudsen ES, Elsaleh H, Fluge Ø, Vonen B, Myrvold HE, Leh S, Tveit KM, Pestell RG, Dahl O) Br J Cancer 2012 Nov 06;107(10):1684-91 PMID: 23099809 PMCID: PMC3493874 SCOPUS ID: 2-s2.0-84869089879 10/27/2012 19 Citations

Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes. (Peck AR, Witkiewicz AK, Liu C, Klimowicz AC, Stringer GA, Pequignot E, Freydin B, Yang N, Ertel A, Tran TH, Girondo MA, Rosenberg AL, Hooke JA, Kovatich AJ, Shriver CD, Rimm DL, Magliocco AM, Hyslop T, Rui H) Breast Cancer Res 2012 Oct 04;14(5):R130 PMID: 23036105 PMCID: PMC4053108 SCOPUS ID: 2-s2.0-84866893124 10/06/2012 59 Citations

Reply to A. Italiano (Peck AR, Witkiewicz AK, Liu C, Stringer GA, Klimowicz AC, Pequignot EC, Freydin BC, Tran TH, Yang N, Rosenberg AL, Hooke JA, Kovatich AJ, Nevalainen MT, Shriver CD, Hyslop T, Sauter G, Rimm DL, Magliocco AM, Rui H) Journal of Clinical Oncology 10 December 2011;29(35):4718-4719 SCOPUS ID: 2-s2.0-83255162612 12/10/2011 1 Citation

Cyclin D3 compensates for the loss of cyclin D1 during ErbB2-induced mammary tumor initiation and progression. (Zhang Q, Sakamoto K, Liu C, Triplett AA, Lin WC, Rui H, Wagner KU) Cancer Res 2011 Dec 15;71(24):7513-24 PMID: 22037875 PMCID: PMC3242818 SCOPUS ID: 2-s2.0-84255170423 11/01/2011 29 Citations

Signal transducer and activator of transcription-3 and breast cancer prognosis. (Sato T, Neilson LM, Peck AR, Liu C, Tran TH, Witkiewicz A, Hyslop T, Nevalainen MT, Sauter G, Rui H) Am J Cancer Res 2011;1(3):347-55 PMID: 21776434 PMCID: PMC3138712 07/22/2011

Inflammatory signaling compromises cell responses to interferon alpha. (Huangfu WC, Qian J, Liu C, Liu J, Lokshin AE, Baker DP, Rui H, Fuchs SY) Oncogene 2012 Jan 12;31(2):161-72 PMID: 21666722 PMCID: PMC3175348 SCOPUS ID: 2-s2.0-84855769864 06/15/2011 51 Citations

Design and Synthesis of a Fluorescently End-Labeled Poly(β-amino ester): Application to the Characterization of Degradable Polyelectrolyte Multilayers. (Bechler SL, Lynn DM) J Polym Sci A Polym Chem 2011 Apr 01;49(7):1572-1581 PMID: 21666772 PMCID: PMC3110734 SCOPUS ID: 2-s2.0-79952151590 06/15/2011 10 Citations

Melanoma cell-secreted soluble factor that stimulates ubiquitination and degradation of the interferon alpha receptor and attenuates its signaling. (HuangFu WC, Qian J, Liu C, Rui H, Fuchs SY) Pigment Cell Melanoma Res 2010 Dec;23(6):838-40 PMID: 21644263 PMCID: PMC3688261 SCOPUS ID: 2-s2.0-78049234828 06/07/2011 8 Citations

Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure. (Peck AR, Witkiewicz AK, Liu C, Stringer GA, Klimowicz AC, Pequignot E, Freydin B, Tran TH, Yang N, Rosenberg AL, Hooke JA, Kovatich AJ, Nevalainen MT, Shriver CD, Hyslop T, Sauter G, Rimm DL, Magliocco AM, Rui H) J Clin Oncol 2011 Jun 20;29(18):2448-58 PMID: 21576635 PMCID: PMC3675698 SCOPUS ID: 2-s2.0-79959309120 05/18/2011 78 Citations

Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer. (Li D, Zhao Y, Liu C, Chen X, Qi Y, Jiang Y, Zou C, Zhang X, Liu S, Wang X, Zhao D, Sun Q, Zeng Z, Dress A, Lin MC, Kung HF, Rui H, Liu LZ, Mao F, Jiang BH, Lai L) Clin Cancer Res 2011 Apr 01;17(7):1722-30 PMID: 21350001 SCOPUS ID: 2-s2.0-79953330808 02/26/2011 256 Citations

Differential expression of arrestins is a predictor of breast cancer progression and survival. (Michal AM, Peck AR, Tran TH, Liu C, Rimm DL, Rui H, Benovic JL) Breast Cancer Res Treat 2011 Dec;130(3):791-807 PMID: 21318602 PMCID: PMC3156829 SCOPUS ID: 2-s2.0-82255163335 02/15/2011 11 Citations

Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer. (Arendt LM, Rugowski DE, Grafwallner-Huseth TA, Garcia-Barchino MJ, Rui H, Schuler LA) Breast Cancer Res 2011 Jan 28;13(1):R11 PMID: 21276249 PMCID: PMC3109579 SCOPUS ID: 2-s2.0-84860390313 02/01/2011 52 Citations

Increased SIAH expression predicts ductal carcinoma in situ (DCIS) progression to invasive carcinoma. (Behling KC, Tang A, Freydin B, Chervoneva I, Kadakia S, Schwartz GF, Rui H, Witkiewicz AK) Breast Cancer Res Treat 2011 Oct;129(3):717-24 PMID: 21088888 PMCID: PMC3730842 SCOPUS ID: 2-s2.0-80052598428 11/23/2010 18 Citations

Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferation. (Varghese B, Swaminathan G, Plotnikov A, Tzimas C, Yang N, Rui H, Fuchs SY) Mol Endocrinol 2010 Dec;24(12):2356-65 PMID: 20962042 PMCID: PMC2999476 SCOPUS ID: 2-s2.0-78649416447 10/22/2010 23 Citations

PTP1B suppresses prolactin activation of Stat5 in breast cancer cells. (Johnson KJ, Peck AR, Liu C, Tran TH, Utama FE, Sjolund AB, Schaber JD, Witkiewicz AK, Rui H) Am J Pathol 2010 Dec;177(6):2971-83 PMID: 20952588 PMCID: PMC2993292 SCOPUS ID: 2-s2.0-78650210970 10/19/2010 49 Citations

RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response. (Ertel A, Dean JL, Rui H, Liu C, Witkiewicz AK, Knudsen KE, Knudsen ES) Cell Cycle 2010 Oct 15;9(20):4153-63 PMID: 20948315 PMCID: PMC3055199 SCOPUS ID: 2-s2.0-77958510718 10/16/2010 129 Citations

N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells. (Dagvadorj A, Tan SH, Liao Z, Xie J, Nurmi M, Alanen K, Rui H, Mirtti T, Nevalainen MT) Int J Biochem Cell Biol 2010 Dec;42(12):2037-46 PMID: 20854925 PMCID: PMC2982800 SCOPUS ID: 2-s2.0-78149283094 09/22/2010 18 Citations

HuR status is a powerful marker for prognosis and response to gemcitabine-based chemotherapy for resected pancreatic ductal adenocarcinoma patients. (Richards NG, Rittenhouse DW, Freydin B, Cozzitorto JA, Grenda D, Rui H, Gonye G, Kennedy EP, Yeo CJ, Brody JR, Witkiewicz AK) Ann Surg 2010 Sep;252(3):499-505; discussion 505-6 PMID: 20739850 SCOPUS ID: 2-s2.0-77956222392 08/27/2010 86 Citations

Protocol for constructing tissue arrays by cutting edge matrix assembly. (Tran TH, Lin J, Sjolund AB, Utama FE, Rui H) Methods Mol Biol 2010;664:45-52 PMID: 20690051 SCOPUS ID: 2-s2.0-79952108606 08/07/2010 5 Citations

Stromal CD10 and SPARC expression in ductal carcinoma in situ (DCIS) patients predicts disease recurrence. (Witkiewicz AK, Freydin B, Chervoneva I, Potoczek M, Rizzo W, Rui H, Brody JR, Schwartz GF, Lisanti MP) Cancer Biol Ther 2010 Aug 15;10(4):391-6 PMID: 20574156 PMCID: PMC3040854 SCOPUS ID: 2-s2.0-77956408178 06/25/2010 40 Citations

Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism. (Tran TH, Utama FE, Lin J, Yang N, Sjolund AB, Ryder A, Johnson KJ, Neilson LM, Liu C, Brill KL, Rosenberg AL, Witkiewicz AK, Rui H) Cancer Res 2010 Feb 15;70(4):1711-21 PMID: 20124477 PMCID: PMC2822876 SCOPUS ID: 2-s2.0-76749106107 02/04/2010 59 Citations

STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells. (Nagy ZS, LeBaron MJ, Ross JA, Mitra A, Rui H, Kirken RA) Mol Cancer 2009 Aug 26;8:67 PMID: 19709433 PMCID: PMC2741462 SCOPUS ID: 2-s2.0-70350087559 08/28/2009 28 Citations

Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer. (Comstock CE, Augello MA, Benito RP, Karch J, Tran TH, Utama FE, Tindall EA, Wang Y, Burd CJ, Groh EM, Hoang HN, Giles GG, Severi G, Hayes VM, Henderson BE, Le Marchand L, Kolonel LN, Haiman CA, Baffa R, Gomella LG, Knudsen ES, Rui H, Henshall SM, Sutherland RL, Knudsen KE) Clin Cancer Res 2009 Sep 01;15(17):5338-49 PMID: 19706803 PMCID: PMC2849314 SCOPUS ID: 2-s2.0-65049089363 08/27/2009 71 Citations

Ovarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processes. (Arendt LM, Evans LC, Rugowski DE, Garcia-Barchino MJ, Rui H, Schuler LA) J Endocrinol 2009 Oct;203(1):99-110 PMID: 19635758 PMCID: PMC2841967 SCOPUS ID: 2-s2.0-70349758953 07/29/2009 22 Citations

The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling. (Popov VM, Zhou J, Shirley LA, Quong J, Yeow WS, Wright JA, Wu K, Rui H, Vadlamudi RK, Jiang J, Kumar R, Wang C, Pestell RG) Cancer Res 2009 Jul 15;69(14):5752-60 PMID: 19605405 PMCID: PMC3244171 SCOPUS ID: 2-s2.0-67650996915 07/17/2009 50 Citations

Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer. (Witkiewicz AK, Dasgupta A, Nguyen KH, Liu C, Kovatich AJ, Schwartz GF, Pestell RG, Sotgia F, Rui H, Lisanti MP) Cancer Biol Ther 2009 Jun;8(11):1071-9 PMID: 19502809 SCOPUS ID: 2-s2.0-67049120444 06/09/2009 113 Citations

Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions. (Mercier I, Casimiro MC, Zhou J, Wang C, Plymire C, Bryant KG, Daumer KM, Sotgia F, Bonuccelli G, Witkiewicz AK, Lin J, Tran TH, Milliman J, Frank PG, Jasmin JF, Rui H, Pestell RG, Lisanti MP) Am J Pathol 2009 Apr;174(4):1172-90 PMID: 19342371 PMCID: PMC2671351 SCOPUS ID: 2-s2.0-65349132368 04/04/2009 52 Citations

Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome. (Millar EK, Dean JL, McNeil CM, O'Toole SA, Henshall SM, Tran T, Lin J, Quong A, Comstock CE, Witkiewicz A, Musgrove EA, Rui H, Lemarchand L, Setiawan VW, Haiman CA, Knudsen KE, Sutherland RL, Knudsen ES) Oncogene 2009 Apr 16;28(15):1812-20 PMID: 19287456 PMCID: PMC3073345 SCOPUS ID: 2-s2.0-65049084565 03/17/2009 68 Citations

Impaired turnover of prolactin receptor contributes to transformation of human breast cells. (Plotnikov A, Varghese B, Tran TH, Liu C, Rui H, Fuchs SY) Cancer Res 2009 Apr 01;69(7):3165-72 PMID: 19276348 PMCID: PMC2664855 SCOPUS ID: 2-s2.0-66149095511 03/12/2009 39 Citations

Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation. (Sotgia F, Casimiro MC, Bonuccelli G, Liu M, Whitaker-Menezes D, Er O, Daumer KM, Mercier I, Witkiewicz AK, Minetti C, Capozza F, Gormley M, Quong AA, Rui H, Frank PG, Milliman JN, Knudsen ES, Zhou J, Wang C, Pestell RG, Lisanti MP) Am J Pathol 2009 Feb;174(2):613-29 PMID: 19164602 PMCID: PMC2630569 SCOPUS ID: 2-s2.0-59649087892 01/24/2009 16 Citations

Insensitivity of human prolactin receptors to nonhuman prolactins: relevance for experimental modeling of prolactin receptor-expressing human cells. (Utama FE, Tran TH, Ryder A, LeBaron MJ, Parlow AF, Rui H) Endocrinology 2009 Apr;150(4):1782-90 PMID: 19022890 PMCID: PMC2659276 SCOPUS ID: 2-s2.0-63849281305 11/22/2008 35 Citations

ErbB2 induces Notch1 activity and function in breast cancer cells. (Lindsay J, Jiao X, Sakamaki T, Casimiro MC, Shirley LA, Tran TH, Ju X, Liu M, Li Z, Wang C, Katiyar S, Rao M, Allen KG, Glazer RI, Ge C, Stanley P, Lisanti MP, Rui H, Pestell RG) Clin Transl Sci 2008 Sep;1(2):107-15 PMID: 20443831 PMCID: PMC3590841 SCOPUS ID: 2-s2.0-75149125614 09/01/2008 39 Citations

Cyclin D1b is aberrantly regulated in response to therapeutic challenge and promotes resistance to estrogen antagonists. (Wang Y, Dean JL, Millar EK, Tran TH, McNeil CM, Burd CJ, Henshall SM, Utama FE, Witkiewicz A, Rui H, Sutherland RL, Knudsen KE, Knudsen ES) Cancer Res 2008 Jul 15;68(14):5628-38 PMID: 18632615 PMCID: PMC8220573 SCOPUS ID: 2-s2.0-48649103464 07/18/2008 53 Citations

Oncogene-mediated inhibition of glycogen synthase kinase 3 beta impairs degradation of prolactin receptor. (Plotnikov A, Li Y, Tran TH, Tang W, Palazzo JP, Rui H, Fuchs SY) Cancer Res 2008 Mar 01;68(5):1354-61 PMID: 18316598 SCOPUS ID: 2-s2.0-40449130327 03/05/2008 39 Citations

Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression. (Wagner KU, Rui H) J Mammary Gland Biol Neoplasia 2008 Mar;13(1):93-103 PMID: 18228120 SCOPUS ID: 2-s2.0-40449135440 01/30/2008 123 Citations

Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways. (Neilson LM, Zhu J, Xie J, Malabarba MG, Sakamoto K, Wagner KU, Kirken RA, Rui H) Mol Endocrinol 2007 Sep;21(9):2218-32 PMID: 17550976 SCOPUS ID: 2-s2.0-34548348216 06/07/2007 53 Citations

Insulin receptor substrate-1 regulates the transformed phenotype of BT-20 human mammary cancer cells. (Dalmizrak O, Wu A, Chen J, Sun H, Utama FE, Zambelli D, Tran TH, Rui H, Baserga R) Cancer Res 2007 Mar 01;67(5):2124-30 PMID: 17332342 SCOPUS ID: 2-s2.0-33947286775 03/03/2007 27 Citations

In vivo response-based identification of direct hormone target cell populations using high-density tissue arrays. (LeBaron MJ, Ahonen TJ, Nevalainen MT, Rui H) Endocrinology 2007 Mar;148(3):989-1008 PMID: 17138649 SCOPUS ID: 2-s2.0-33847059271 12/02/2006 30 Citations

Caveolin-1, mammary stem cells, and estrogen-dependent breast cancers. (Sotgia F, Rui H, Bonuccelli G, Mercier I, Pestell RG, Lisanti MP) Cancer Res 2006 Nov 15;66(22):10647-51 PMID: 17108100 SCOPUS ID: 2-s2.0-33845338025 11/17/2006 53 Citations

Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells. (Williams TM, Sotgia F, Lee H, Hassan G, Di Vizio D, Bonuccelli G, Capozza F, Mercier I, Rui H, Pestell RG, Lisanti MP) Am J Pathol 2006 Nov;169(5):1784-801 PMID: 17071600 PMCID: PMC1780215 SCOPUS ID: 2-s2.0-33845312826 10/31/2006 76 Citations

A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor. (Nagy ZS, Rui H, Stepkowski SM, Karras J, Kirken RA) J Immunol 2006 Oct 15;177(8):5032-40 PMID: 17015686 SCOPUS ID: 2-s2.0-33749529310 10/04/2006 21 Citations

Human prolactin receptors are insensitive to mouse prolactin: implications for xenotransplant modeling of human breast cancer in mice. (Utama FE, LeBaron MJ, Neilson LM, Sultan AS, Parlow AF, Wagner KU, Rui H) J Endocrinol 2006 Mar;188(3):589-601 PMID: 16522738 SCOPUS ID: 2-s2.0-33645213701 03/09/2006 49 Citations

Creating tissue microarrays by cutting-edge matrix assembly. (Rui H, LeBaron MJ) Expert Rev Med Devices 2005 Nov;2(6):673-80 PMID: 16293094 SCOPUS ID: 2-s2.0-28244471657 11/19/2005 13 Citations

The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells. (Selliah N, Zhang M, DeSimone D, Kim H, Brunner M, Ittenbach RF, Rui H, Cron RQ, Finkel TH) Virology 2006 Jan 20;344(2):283-91 PMID: 16289657 SCOPUS ID: 2-s2.0-30044445017 11/18/2005 37 Citations

Ultrahigh density microarrays of solid samples. (LeBaron MJ, Crismon HR, Utama FE, Neilson LM, Sultan AS, Johnson KJ, Andersson EC, Rui H) Nat Methods 2005 Jul;2(7):511-3 PMID: 15973421 SCOPUS ID: 2-s2.0-23644452105 06/24/2005 33 Citations

Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer. (LeBaron MJ, Xie J, Rui H) Mol Cancer 2005 Feb 01;4(1):6 PMID: 15686596 PMCID: PMC549029 SCOPUS ID: 2-s2.0-13644260809 02/03/2005 23 Citations

Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells. (Sultan AS, Xie J, LeBaron MJ, Ealley EL, Nevalainen MT, Rui H) Oncogene 2005 Jan 27;24(5):746-60 PMID: 15592524 SCOPUS ID: 2-s2.0-13444263403 12/14/2004 160 Citations

Generation of a conditional knockout allele for the Janus kinase 2 (Jak2) gene in mice. (Krempler A, Qi Y, Triplett AA, Zhu J, Rui H, Wagner KU) Genesis 2004 Sep;40(1):52-7 PMID: 15354294 SCOPUS ID: 2-s2.0-10644224189 09/09/2004 77 Citations

Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice. (Wagner KU, Krempler A, Triplett AA, Qi Y, George NM, Zhu J, Rui H) Mol Cell Biol 2004 Jun;24(12):5510-20 PMID: 15169911 PMCID: PMC419899 SCOPUS ID: 2-s2.0-2942587457 06/01/2004 127 Citations

Signal transducer and activator of transcription-5 activation and breast cancer prognosis. (Nevalainen MT, Xie J, Torhorst J, Bubendorf L, Haas P, Kononen J, Sauter G, Rui H) J Clin Oncol 2004 Jun 01;22(11):2053-60 PMID: 15169792 SCOPUS ID: 2-s2.0-2942672845 06/01/2004 193 Citations

Erratum: Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells (Journal of Biological Chemistry (2003) 278 (27287-27292)) (Ahonen TJ, Xie J, LeBaron MJ, Zhu J, Nurmi M, Alanen K, Rui H, Nevalainen MT) Journal of Biological Chemistry 3 October 2003;278(40):39259 SCOPUS ID: 2-s2.0-0141865756 10/03/2003

Role of Stat5 in type I interferon-signaling and transcriptional regulation. (Uddin S, Lekmine F, Sassano A, Rui H, Fish EN, Platanias LC) Biochem Biophys Res Commun 2003 Aug 22;308(2):325-30 PMID: 12901872 SCOPUS ID: 2-s2.0-0043095397 08/07/2003 53 Citations

Prolactin (Rui H, Nevalainen MT) The Cytokine Handbook July 07, 2003:115-147 SCOPUS ID: 2-s2.0-84942876458 07/07/2003 1 Citation

Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells. (Ahonen TJ, Xie J, LeBaron MJ, Zhu J, Nurmi M, Alanen K, Rui H, Nevalainen MT) J Biol Chem 2003 Jul 18;278(29):27287-92 PMID: 12719422 SCOPUS ID: 2-s2.0-0038711502 04/30/2003 110 Citations

STAT5a activation mediates the epithelial to mesenchymal transition induced by oncogenic RhoA. (Benitah SA, Valerón PF, Rui H, Lacal JC) Mol Biol Cell 2003 Jan;14(1):40-53 PMID: 12529425 PMCID: PMC140226 SCOPUS ID: 2-s2.0-0037243197 01/17/2003 37 Citations

Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways. (Nagy ZS, Wang Y, Erwin-Cohen RA, Aradi J, Monia B, Wang LH, Stepkowski SM, Rui H, Kirken RA) J Leukoc Biol 2002 Oct;72(4):819-28 PMID: 12377952 SCOPUS ID: 2-s2.0-0036826681 10/16/2002 33 Citations

Prostaglandin-E2 enhances EPO-mediated STAT5 transcriptional activity by serine phosphorylation of CREB. (Boer AK, Drayer AL, Rui H, Vellenga E) Blood 2002 Jul 15;100(2):467-73 PMID: 12091337 SCOPUS ID: 2-s2.0-0037098854 07/02/2002 40 Citations

Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium. (Nevalainen MT, Xie J, Bubendorf L, Wagner KU, Rui H) Mol Endocrinol 2002 May;16(5):1108-24 PMID: 11981045 SCOPUS ID: 2-s2.0-0036256358 05/01/2002 70 Citations

Role of tyrosine kinase Jak2 in prolactin-induced differentiation and growth of mammary epithelial cells. (Xie J, LeBaron MJ, Nevalainen MT, Rui H) J Biol Chem 2002 Apr 19;277(16):14020-30 PMID: 11821424 SCOPUS ID: 2-s2.0-0037134424 02/01/2002 40 Citations

PRL signal transduction in the epithelial compartment of rat prostate maintained as long-term organ cultures in vitro. (Ahonen TJ, Härkönen PL, Rui H, Nevalainen MT) Endocrinology 2002 Jan;143(1):228-38 PMID: 11751614 SCOPUS ID: 2-s2.0-0036142679 12/26/2001 49 Citations

Serine phosphorylation of GH-activated signal transducer and activator of transcription 5a (STAT5a) and STAT5b: impact on STAT5 transcriptional activity. (Park SH, Yamashita H, Rui H, Waxman DJ) Mol Endocrinol 2001 Dec;15(12):2157-71 PMID: 11731617 SCOPUS ID: 2-s2.0-0035215369 12/04/2001 60 Citations

Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression. (Yamashita H, Nevalainen MT, Xu J, LeBaron MJ, Wagner KU, Erwin RA, Harmon JM, Hennighausen L, Kirken RA, Rui H) Mol Cell Endocrinol 2001 Oct 25;183(1-2):151-63 PMID: 11604235 SCOPUS ID: 2-s2.0-0035950441 10/18/2001 71 Citations

Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells. (Kirken RA, Erwin RA, Wang L, Wang Y, Rui H, Farrar WL) J Immunol 2000 Nov 01;165(9):5097-104 PMID: 11046040 SCOPUS ID: 2-s2.0-0034327770 10/25/2000 45 Citations

Epithelial defect in prostates of Stat5a-null mice. (Nevalainen MT, Ahonen TJ, Yamashita H, Chandrashekar V, Bartke A, Grimley PM, Robinson GW, Hennighausen L, Rui H) Lab Invest 2000 Jul;80(7):993-1006 PMID: 10908145 SCOPUS ID: 2-s2.0-0033914135 07/25/2000 36 Citations

Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation. (Grimley PM, Dong F, Rui H) Cytokine Growth Factor Rev 1999 Jun;10(2):131-57 PMID: 10743504 SCOPUS ID: 2-s2.0-0032831735 04/01/2000 185 Citations

Prolactin is a survival factor for androgen-deprived rat dorsal and lateral prostate epithelium in organ culture. (Ahonen TJ, Härkönen PL, Laine J, Rui H, Martikainen PM, Nevalainen MT) Endocrinology 1999 Nov;140(11):5412-21 PMID: 10537173 SCOPUS ID: 2-s2.0-0033303824 10/28/1999 86 Citations

A lymphoma growth inhibitor blocks some but not all prolactin-stimulated signaling pathways. (Yamashita H, Xu J, Erwin RA, Larner AC, Rui H) J Biol Chem 1999 May 21;274(21):14699-705 PMID: 10329665 SCOPUS ID: 2-s2.0-0033591389 05/18/1999 6 Citations

Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells. (Yamashita H, Xu J, Erwin RA, Farrar WL, Kirken RA, Rui H) J Biol Chem 1998 Nov 13;273(46):30218-24 PMID: 9804779 SCOPUS ID: 2-s2.0-0032515146 11/07/1998 132 Citations

Prolonged STAT1 activation related to the growth arrest of malignant lymphoma cells by interferon-alpha. (Grimley PM, Fang H, Rui H, Petricoin EF 3rd, Ray S, Dong F, Fields KH, Hu R, Zoon KC, Audet S, Beeler J) Blood 1998 Apr 15;91(8):3017-27 PMID: 9531615 SCOPUS ID: 2-s2.0-0032523158 05/16/1998 36 Citations

Prolactin activates Stat1 but does not antagonize Stat1 activation and growth inhibition by type I interferons in human breast cancer cells. (Schaber JD, Fang H, Xu J, Grimley PM, Rui H) Cancer Res 1998 May 01;58(9):1914-9 PMID: 9581833 SCOPUS ID: 2-s2.0-0032080788 05/15/1998 31 Citations

Activation of the Jak2-Stat5 signaling pathway in Nb2 lymphoma cells by an anti-apoptotic agent, aurintricarboxylic acid. (Rui H, Xu J, Mehta S, Fang H, Williams J, Dong F, Grimley PM) J Biol Chem 1998 Jan 02;273(1):28-32 PMID: 9417042 SCOPUS ID: 2-s2.0-0031982630 02/07/1998 60 Citations

Two discrete regions of interleukin-2 (IL2) receptor beta independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase. (Kirken RA, Malabarba MG, Xu J, DaSilva L, Erwin RA, Liu X, Hennighausen L, Rui H, Farrar WL) J Biol Chem 1997 Jun 13;272(24):15459-65 PMID: 9182578 SCOPUS ID: 2-s2.0-0030919149 06/13/1997 58 Citations

Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes. (Kirken RA, Malabarba MG, Xu J, Liu X, Farrar WL, Hennighausen L, Larner AC, Grimley PM, Rui H) J Biol Chem 1997 May 30;272(22):14098-103 PMID: 9162035 SCOPUS ID: 2-s2.0-0030983551 05/30/1997 73 Citations

Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha. (Malabarba MG, Rui H, Deutsch HH, Chung J, Kalthoff FS, Farrar WL, Kirken RA) Biochem J 1996 Nov 01;319 ( Pt 3)(Pt 3):865-72 PMID: 8920992 PMCID: PMC1217868 SCOPUS ID: 2-s2.0-0029855722 11/01/1996 51 Citations

Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580. (DaSilva L, Rui H, Erwin RA, Howard OM, Kirken RA, Malabarba MG, Hackett RH, Larner AC, Farrar WL) Mol Cell Endocrinol 1996 Mar 25;117(2):131-40 PMID: 8737372 SCOPUS ID: 2-s2.0-0030000424 03/25/1996 143 Citations

Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain. (Kirken RA, Rui H, Malabarba MG, Howard OM, Kawamura M, O'Shea JJ, Farrar WL) Cytokine 1995 Oct;7(7):689-700 PMID: 8580378 SCOPUS ID: 2-s2.0-0028889726 10/01/1995 76 Citations

Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless. (Erwin RA, Kirken RA, Malabarba MG, Farrar WL, Rui H) Endocrinology 1995 Aug;136(8):3512-8 PMID: 7628388 SCOPUS ID: 2-s2.0-0029112369 08/01/1995 109 Citations

Cloning of the gene encoding rat JAK2, a protein tyrosine kinase. (Duhé RJ, Rui H, Greenwood JD, Garvey K, Farrar WL) Gene 1995 Jun 09;158(2):281-5 PMID: 7607555 SCOPUS ID: 2-s2.0-0029059915 06/09/1995 26 Citations

Activation of JAK3, but not JAK1, is critical to interleukin-4 (IL4) stimulated proliferation and requires a membrane-proximal region of IL4 receptor alpha. (Malabarba MG, Kirken RA, Rui H, Koettnitz K, Kawamura M, O'Shea JJ, Kalthoff FS, Farrar WL) J Biol Chem 1995 Apr 21;270(16):9630-7 PMID: 7721895 SCOPUS ID: 2-s2.0-0028901042 04/21/1995 56 Citations

Effects of growth hormone and prolactin immune development and function. (Murphy WJ, Rui H, Longo DL) Life Sci 1995;57(1):1-14 PMID: 7596216 SCOPUS ID: 2-s2.0-0029107439 01/01/1995 93 Citations

[Male infertility. Significance of life and occupation]. (Oldereid NB, Rui H, Purvis K) Tidsskr Nor Laegeforen 1994 Nov 20;114(28):3308-11 PMID: 7809887 SCOPUS ID: 2-s2.0-0028777781 11/20/1994 3 Citations

JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization. (Rui H, Lebrun JJ, Kirken RA, Kelly PA, Farrar WL) Endocrinology 1994 Oct;135(4):1299-306 PMID: 7925093 SCOPUS ID: 2-s2.0-0027965825 10/01/1994 122 Citations

Identification of interleukin-2 receptor-associated tyrosine kinase p116 as novel leukocyte-specific Janus kinase. (Kirken RA, Rui H, Malabarba MG, Farrar WL) J Biol Chem 1994 Jul 22;269(29):19136-41 PMID: 7518451 SCOPUS ID: 2-s2.0-0028242360 07/22/1994 56 Citations

Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors. (DaSilva L, Howard OM, Rui H, Kirken RA, Farrar WL) J Biol Chem 1994 Jul 15;269(28):18267-70 PMID: 8034567 SCOPUS ID: 2-s2.0-0028301226 07/15/1994 134 Citations

Activation of receptor-associated tyrosine kinase JAK2 by prolactin. (Rui H, Kirken RA, Farrar WL) J Biol Chem 1994 Feb 18;269(7):5364-8 PMID: 7508935 SCOPUS ID: 2-s2.0-0027941433 02/18/1994 292 Citations

Involvement of JAK-family tyrosine kinases in hematopoietin receptor signal transduction. (Kirken RA, Rui H, Howard OM, Farrar WL) Prog Growth Factor Res 1994;5(2):195-211 PMID: 7919224 SCOPUS ID: 2-s2.0-0028002294 01/01/1994 11 Citations

Characterization of an interleukin-2 (IL-2)-induced tyrosine phosphorylated 116-kDa protein associated with the IL-2 receptor beta-subunit. (Kirken RA, Rui H, Evans GA, Farrar WL) J Biol Chem 1993 Oct 25;268(30):22765-70 PMID: 7693677 SCOPUS ID: 2-s2.0-0027440218 10/25/1993 20 Citations

Function associated with IL-2 receptor-beta on human neutrophils. Mechanism of activation of antifungal activity against Candida albicans by IL-2. (Djeu JY, Liu JH, Wei S, Rui H, Pearson CA, Leonard WJ, Blanchard DK) J Immunol 1993 Feb 01;150(3):960-70 PMID: 8380826 SCOPUS ID: 2-s2.0-0027167530 02/01/1993 90 Citations

Identification of Intracellular Mediators of the Actions of Cytokines: Identifying Proteins Involved in Kinase Signaling Pathways (Evans GA, Rui H, Farrar WL) Methods in Neurosciences 1 January 1993;16(PA):49-66 SCOPUS ID: 2-s2.0-85023414508 01/01/1993

The value of anamnestic information regarding previous genital infection in male fertility investigation. (Oldereid NB, Rui H, Purvis K) Eur J Obstet Gynecol Reprod Biol 1992 Dec 28;47(3):207-12 PMID: 1294407 SCOPUS ID: 2-s2.0-0027053966 12/28/1992 2 Citations

Prolactin receptor triggering. Evidence for rapid tyrosine kinase activation. (Rui H, Djeu JY, Evans GA, Kelly PA, Farrar WL) J Biol Chem 1992 Nov 25;267(33):24076-81 PMID: 1385436 SCOPUS ID: 2-s2.0-0027057982 11/25/1992 105 Citations

Life styles of men in barren couples and their relationship to sperm quality. (Oldereid NB, Rui H, Purvis K) Int J Fertil 1992;37(6):343-9 PMID: 1360454 SCOPUS ID: 2-s2.0-0026442120 11/01/1992 49 Citations

Lifestyles of men in barren couples and their relationships to sperm quality. (Oldereid NB, Rui H, Purvis K) Eur J Obstet Gynecol Reprod Biol 1992 Jan 09;43(1):51-7 PMID: 1737609 SCOPUS ID: 2-s2.0-0026569593 01/09/1992 25 Citations

Short-term effects of treatment with simvastatin on testicular function in patients with heterozygous familial hypercholesterolaemia. (Purvis K, Tollefsrud A, Rui H, Haug E, Norseth J, Viksmoen L, Ose L, Lund H) Eur J Clin Pharmacol 1992;42(1):61-4 PMID: 1541317 SCOPUS ID: 2-s2.0-0026604874 01/01/1992 35 Citations

Prolactin activates protein kinase C and stimulates growth-related gene expression in rat liver. (Crowe PD, Buckley AR, Zorn NE, Rui H) Mol Cell Endocrinol 1991 Aug;79(1-3):29-35 PMID: 1718797 SCOPUS ID: 2-s2.0-0025826725 08/01/1991 43 Citations

[Infertility studies in men]. (Oldereid NB, Rui H, Purvis K) Tidsskr Nor Laegeforen 1991 Apr 20;111(10):1265-8 PMID: 2042142 SCOPUS ID: 2-s2.0-0026428436 04/20/1991

Male partners in infertile couples. Personal attitudes and contact with the Norwegian health service. (Oldereid NB, Rui H, Purvis K) Scand J Soc Med 1990 Sep;18(3):207-11 PMID: 2237329 SCOPUS ID: 2-s2.0-84964185680 09/01/1990 17 Citations

Application of flow cytometry to studies on the human acrosome. (Purvis K, Rui H, Schølberg A, Hesla S, Clausen OP) J Androl 1990;11(4):361-6 PMID: 2211342 SCOPUS ID: 2-s2.0-0025007067 07/01/1990 24 Citations

Polyamines and other accessory sex gland secretions in human seminal plasma 8 years after vasectomy. (Jakobsen H, Rui H, Thomassen Y, Hald T, Purvis K) J Reprod Fertil 1989 Sep;87(1):39-45 PMID: 2621711 SCOPUS ID: 2-s2.0-0024450791 09/01/1989 20 Citations

Cigarette smoking and human sperm quality assessed by laser-Doppler spectroscopy and DNA flow cytometry. (Oldereid NB, Rui H, Clausen OP, Purvis K) J Reprod Fertil 1989 Jul;86(2):731-6 PMID: 2760898 SCOPUS ID: 2-s2.0-0024316413 07/01/1989 38 Citations

Stability of sperm characteristics in men with disturbances in sperm quality. (Purvis K, Tollefsrud A, Rui H) Int J Androl 1989 Jun;12(3):171-8 PMID: 2767777 SCOPUS ID: 2-s2.0-0024308351 06/01/1989 12 Citations

Sperm adenylyl cyclase in young and middle-aged men. (Rui H, Purvis K, Gordeladze JO) Andrologia 1989;21(2):131-5 PMID: 2712367 SCOPUS ID: 2-s2.0-0024544676 03/01/1989 1 Citation

[Smoking and sperm quality in men undergoing fertility studies]. (Rui H, Oldereid NB, Purvis K) Tidsskr Nor Laegeforen 1989 Feb 20;109(5):573-5 PMID: 2922717 SCOPUS ID: 2-s2.0-0024974350 02/20/1989 1 Citation

Correlates of human sperm motility assessed by laser Doppler spectroscopy. (Purvis K, Tollefsrud A, Rui H) Int J Androl 1989 Feb;12(1):10-6 PMID: 2714870 SCOPUS ID: 2-s2.0-0024521503 02/01/1989 15 Citations

Distribution of Thyroliberin (TRH)- and 12-O-tetradecanoylphorbol 13-acetate (TPA)-activated adenylyl cyclase in normal and neoplastic tissue with special reference to the prostate. (Gordeladze JO, Rur H, Attramadal A, Tveter K, Gautvik KM, Purvis K) Mol Cell Endocrinol 1988 Aug;58(2-3):287-90 PMID: 3145232 SCOPUS ID: 2-s2.0-0023681301 08/01/1988 4 Citations

[Sperm motility. Physiology, analytical methods and clinical aspects]. (Purvis K, Attramadal A, Rui H, Tollefsrud A, Abyholm T, Magnus O) Tidsskr Nor Laegeforen 1988 May 20;108(14):1128-32 PMID: 3388340 SCOPUS ID: 2-s2.0-0024292734 05/20/1988

Secretory function of the prostate gland. (Purvis K, Attramadal A, Rui H) Scand J Urol Nephrol Suppl 1988;107:46-51 PMID: 3287597 SCOPUS ID: 2-s2.0-0023708060 01/01/1988 2 Citations

Hormonal control of prostate function. (Rui H, Purvis K) Scand J Urol Nephrol Suppl 1988;107:32-8 PMID: 2897713 SCOPUS ID: 2-s2.0-0023803816 01/01/1988 14 Citations

High-affinity, calmodulin-dependent isoforms of cyclic nucleotide phosphodiesterase in rat testis. (Purvis K, Rui H) Methods Enzymol 1988;159:675-85 PMID: 2842629 SCOPUS ID: 2-s2.0-0023810346 01/01/1988 5 Citations

Prostatic secretory products as markers of prostatic neoplasms. (Purvis K, Mevåg B, Teige B, Torjesen P, Jakobsen H, Rui H, Attramadal A) APMIS Suppl 1988;2:224-37 PMID: 2460112 SCOPUS ID: 2-s2.0-0023709993 01/01/1988

Thyrotrophin-releasing hormone in human ejaculate. (Rui H, Welinder BS, Purvis K, Dolva O) J Endocrinol 1987 Aug;114(2):329-34 PMID: 3116142 SCOPUS ID: 2-s2.0-0023212056 08/01/1987 7 Citations

Independent control of citrate production and ornithine decarboxylase by prolactin in the lateral lobe of the rat prostate. (Rui H, Purvis K) Mol Cell Endocrinol 1987 Jul;52(1-2):91-5 PMID: 3114026 SCOPUS ID: 2-s2.0-0023183937 07/01/1987 7 Citations

Androgen interaction with the polyamine system of the rat prostate. (Rui H, Brekke I, Mørkås L, Purvis K) Andrologia 1987;19(2):134-42 PMID: 3688484 SCOPUS ID: 2-s2.0-0023092286 03/01/1987 11 Citations

Prolactin selectively stimulates ornithine decarboxylase in the lateral lobe of the rat prostate. (Rui H, Purvis K) Mol Cell Endocrinol 1987 Mar;50(1-2):89-97 PMID: 3582728 SCOPUS ID: 2-s2.0-0023117453 03/01/1987 14 Citations

Further observations on the autoregulation of the prolactin receptor in rat ventral prostate explants. (Rui H, Brekke I, Torjesen PA, Purvis K) Acta Endocrinol (Copenh) 1987 Mar;114(3):426-32 PMID: 3551431 SCOPUS ID: 2-s2.0-0023139541 03/01/1987 2 Citations

5 Alpha-reductase in the non-secretory cells of the rat ventral prostate epithelium. (Purvis K, Brekke I, Rui H, Sunde A) J Steroid Biochem 1986 Dec;25(6):1023-5 PMID: 3795950 SCOPUS ID: 2-s2.0-0023002744 12/01/1986 2 Citations

Ejaculate composition after masturbation and coitus in the human male. (Purvis K, Magnus O, Mørkås L, Abyholm T, Rui H) Int J Androl 1986 Dec;9(6):401-6 PMID: 3553035 SCOPUS ID: 2-s2.0-0022913609 12/01/1986 17 Citations

Effects of oestrogen-induced hyperprolactinemia on the rat prostate. (Oldereid NB, Thomassen Y, Rui H, Gordeladze JO, Haug E, Purvis K) Andrologia 1986;18(5):516-22 PMID: 3800010 SCOPUS ID: 2-s2.0-0022995790 09/01/1986 4 Citations

Short-term effects of mating on the accessory sex glands of the male rat. (Purvis K, Haug E, Thomassen Y, Mevåg B, Rui H) J Reprod Fertil 1986 Jul;77(2):373-80 PMID: 3735239 SCOPUS ID: 2-s2.0-0022458857 07/01/1986 6 Citations

Time- and temperature-related alterations in seminal plasma constituents after ejaculation. (Rui H, Mørkås L, Purvis K) Int J Androl 1986 Jun;9(3):195-200 PMID: 3804465 SCOPUS ID: 2-s2.0-0023037372 06/01/1986 8 Citations

Homologous up-regulation of the prolactin receptor in rat prostatic explants. (Rui H, Brekke I, Torjesen PA, Purvis K) Mol Cell Endocrinol 1986 Jun;46(1):53-7 PMID: 3011565 SCOPUS ID: 2-s2.0-0022871665 06/01/1986 10 Citations

Accessory sex gland function in normal young (20-25 years) and middle-aged (50-55 years) men. (Rui H, Thomassen Y, Oldereid NB, Purvis K) J Androl 1986;7(2):93-9 PMID: 3957786 SCOPUS ID: 2-s2.0-0022608226 03/01/1986 23 Citations

Biochemical correlates of asthenozoospermia: a lesion at the level of the sperm adenylyl cyclase. (Magnus O, Purvis K, Rui H, Clausen OP, Abyholm T, Gordeladze JO) Arch Androl 1986;17(3):165-72 PMID: 3606270 SCOPUS ID: 2-s2.0-0023225175 01/01/1986 1 Citation

Hormonal activation of the adenylyl cyclases of the rat and human prostate gland. (Purvis K, Rui H, Gordeladze JO, Attramadal H) Prostate 1986;8(1):11-24 PMID: 2418428 SCOPUS ID: 2-s2.0-0022623178 01/01/1986 10 Citations

Biochemical correlates of asthenozoospermia: A lesion at the level of the sperm adenylyl cyclase (Magnus , Purvis K, Rui H, Clausen OPF, Åbyholm T, Gordeladze JO) Systems Biology in Reproductive Medicine 1986;17(3):165-172 SCOPUS ID: 2-s2.0-84907132230 01/01/1986 2 Citations

Short-term effects of prolactin on prostatic function in rats with lisuride-induced hypoprolactinaemia. (Rui H, Haug E, Mevåg B, Thomassen Y, Purvis K) J Reprod Fertil 1985 Nov;75(2):421-32 PMID: 4067923 SCOPUS ID: 2-s2.0-0022351746 11/01/1985 7 Citations

Circadian rhythms in accessory sex gland function in the male rat. (Rui H, Gordeladze JO, Mevåg B, Haug E, Brekke I, Purvis K) Urol Int 1985;40(6):331-6 PMID: 4090105 SCOPUS ID: 2-s2.0-0022385977 01/01/1985 1 Citation

Estrogen receptors in stromal and epithelial fractions of the ventral prostate of rats. (Purvis K, Mørkås L, Rui H, Attramadal A) Arch Androl 1985;15(2-3):143-51 PMID: 3833071 SCOPUS ID: 2-s2.0-84907123743 01/01/1985 7 Citations

Testicular and glandular contributions to the prolactin pool in human semen. (Rui H, Torjesen PA, Jacobsen H, Purvis K) Arch Androl 1985;15(2-3):129-36 PMID: 3833069 SCOPUS ID: 2-s2.0-84907129370 01/01/1985 5 Citations

Two‐dimensional electrophoresis of proteins from different lobes of the rat prostate and seminal vesicle (Gerhardt P, Mevåg B, Rui H, Purvis K, Tveter KJ) The Prostate 1985;7(3):321-326 SCOPUS ID: 2-s2.0-0022243815 01/01/1985 4 Citations

Two-dimensional electrophoresis of proteins in various fractions of the human split ejaculate. (Rui H, Mevåg B, Purvis K) Int J Androl 1984 Dec;7(6):509-20 PMID: 6526515 SCOPUS ID: 2-s2.0-0021703821 12/01/1984 30 Citations

Prolactin desensitizes the prostaglandin E1-dependent adenylyl cyclase in the rat prostate gland. (Rui H, Gordeladze JO, Gautvik KM, Purvis K) Mol Cell Endocrinol 1984 Nov;38(1):53-60 PMID: 6542888 SCOPUS ID: 2-s2.0-0021741567 11/01/1984 10 Citations

Seminal plasma characteristics during frequent ejaculation. (Rui H, Gerhardt P, Mevåg B, Thomassen Y, Purvis K) Int J Androl 1984 Apr;7(2):119-28 PMID: 6724722 SCOPUS ID: 2-s2.0-0021245019 04/01/1984 24 Citations

Current approaches to research on prostatic function and pathology. (Purvis K, Rui H, Attramadal A, Tveter KJ) Eur Surg Res 1984;16 Suppl 2:88-101 PMID: 6202522 SCOPUS ID: 2-s2.0-0021257825 01/01/1984

[Attitude to death and terminal care in Norway]. (Rui H, Bjørnland K, Skipenes G, Haugen K, Purvis K) Tidsskr Nor Laegeforen 1982 Nov 10;102(31):1625-9 PMID: 7167929 SCOPUS ID: 2-s2.0-0020444626 11/10/1982

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Hallgeir Rui MD, PhD

Vice Chair, Professor

Publications (202)