Medical College of Wisconsin
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Hu Yang PhD

Hu Yang PhD profile photo picture

Chair, Professor

Institution: Medical College of Wisconsin
Department: Biomedical Engineering

Member of the Cardiovascular Research Center

Research Areas of Interest

  • Drug Delivery Systems
  • Gene Transfer Techniques
  • Nanomedicine

    • Publications (128)

  • Highly Adaptable Dendrimer Gel Nanoparticles with Dual Targeting of uPAR and Ribonucleotide Reductase R2 for Better Retention and Improved Therapeutic Outcomes in Triple-Negative Breast Cancer. (Chuang HY, Huang D, Qi L, Singh V, Chernatynskaya A, Huang YW, Yang H) ACS Appl Mater Interfaces 2025 Jun 11;17(23):33439-33450 PMID: 40456699 PMCID: PMC12700075 SCOPUS ID: 2-s2.0-105007512700 06/03/2025       3 Citations
  • Enhanced Cholesterol Efflux and Atherosclerosis Regression via CEH Gene Delivery Using Galactose-Functionalized Dendrimeric Nanoparticles. (Kou H, Wang J, Yannie PJ, Huang D, Korzun WJ, Kakiyama G, Ghosh SS, Yang H) ACS Pharmacol Transl Sci 2025 May 09;8(5):1359-1365 PMID: 40370995 PMCID: PMC12070320 SCOPUS ID: 2-s2.0-105002367361 05/15/2025    
  • Scalable Fabrication of High-Payload Dendrimer-Based Nanoparticles for Targeted Atherosclerosis Therapy. (Kou H, Qi L, Huang D, Wu J, Shi H, Yang H) ACS Appl Mater Interfaces 2025 Apr 30;17(17):24953-24962 PMID: 40237537 PMCID: PMC12633720 SCOPUS ID: 2-s2.0-105004055270 04/16/2025       8 Citations
  • Synthesis and Characterization of Free Radical Scavenging Dendrimer Nanogels via Cross-Linking Reaction-Enabled Flash Nanoprecipitation. (Qi L, Huang D, Kou H, Chernatynskaya A, Ercal N, Yang H) Biomacromolecules 2025 May 12;26(5):2986-2995 PMID: 40190197 PMCID: PMC12633722 SCOPUS ID: 2-s2.0-105002022355 04/07/2025       7 Citations
  • Molecular imaging nanoprobes and their applications in atherosclerosis diagnosis. (Kou H, Yang H) Theranostics 2024;14(12):4747-4772 PMID: 39239513 PMCID: PMC11373619 SCOPUS ID: 2-s2.0-85201469163 09/06/2024       13 Citations
  • Antibiotic-Loaded Dendrimer Hydrogels in Periodontal Bone Regeneration: An In Vitro Release Feasibility Study (Yesbeck N, Huang D, Carrico C, Madurantakam P, Yang H) Gels September 2024;10(9) SCOPUS ID: 2-s2.0-85205302174 09/01/2024       3 Citations
  • Injectable Dendrimer Hydrogel Delivers Melphalan in Both Conjugated and Free Forms for Retinoblastoma. (Cooper RC, Wang J, Yang H) Biomacromolecules 2024 Sep 09;25(9):5928-5937 PMID: 39189328 PMCID: PMC11443594 SCOPUS ID: 2-s2.0-85202574494 08/27/2024       13 Citations
  • Consistent Intraocular Pressure Reduction by Solid Drug Nanoparticles in Fixed Combinations for Glaucoma Therapy. (Huang D, Norat P, Qi L, Chernatynskaya A, Cole JD, Mani VJ, Xu L, Liu X, Yang H) Adv Sci (Weinh) 2024 Aug;11(31):e2401648 PMID: 38874068 PMCID: PMC11336906 SCOPUS ID: 2-s2.0-85195867871 06/14/2024       15 Citations
  • Liposomes-Encapsulating Double-Stranded Nucleic Acid (Poly I:C) for Head and Neck Cancer Treatment. (Singh V, Chernatynskaya A, Qi L, Chuang HY, Cole T, Jeyalatha VM, Bhargava L, Yeudall WA, Farkas L, Yang H) ACS Pharmacol Transl Sci 2024 May 10;7(5):1612-1623 PMID: 38751634 PMCID: PMC11092114 SCOPUS ID: 2-s2.0-85190870664 05/16/2024       3 Citations
  • Advancing Simultaneous Extraction and Sequential Single-Particle ICP-MS Analysis for Metallic Nanoparticle Mixtures in Plant Tissues. (Xu L, Ma X, Yang J, Burken JG, Nam P, Shi H, Yang H) J Agric Food Chem 2024 May 15;72(19):11251-11258 PMID: 38699857 SCOPUS ID: 2-s2.0-85192262837 05/03/2024       5 Citations
  • Localized Sustained Release of Copper Enhances Antitumor Effects of Disulfiram in Head and Neck Cancer. (Wang J, Li B, Cooper RC, Huang D, Yang H) Biomacromolecules 2024 May 13;25(5):2770-2779 PMID: 38687975 PMCID: PMC11143945 SCOPUS ID: 2-s2.0-85192159789 04/30/2024       2 Citations
  • RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension (Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam Green, Geoffrey Newcomb, Nuo Sun, Jeffrey C. Horowitz, Aneel R Bhagwani, Hu Yang, Tatiana Kudryashova, Mauricio Rojas, Ana L. Mora, Pearlly Yan, Rama K. Mallampalli, Elena A. Goncharova, David M. Eckmann, Laszlo Farkas) Journal of Clinical Investigation 02/01/2024    
  • Physio-chemical Modifications to Re-engineer Small Extracellular Vesicles for Targeted Anticancer Therapeutics Delivery and Imaging. (Asfiya R, Xu L, Paramanantham A, Kabytaev K, Chernatynskaya A, McCully G, Yang H, Srivastava A) ACS Biomater Sci Eng 2024 Feb 12;10(2):697-722 PMID: 38241003 PMCID: PMC10956554 SCOPUS ID: 2-s2.0-85183014110 01/19/2024       14 Citations
  • Characterization of neural damage and neuroinflammation in Pax6 small-eye mice (James Cole, John A. McDaniel, Joelle Nilak, Ashley Ban, Kara McHaney, Carlos Rodriguez, Zuhaad Hameed, Marta Grannonico, Mingna Liu, Peter A. Netland, Hu Yang, Ignacio Provencio, Xiaorong Liu) Experimental Eye Research 01/01/2024    
  • Study of Legionella pneumophila treatment with copper in drinking water by single cell-ICP-MS. (Xu L, Sigler A, Chernatynskaya A, Rasmussen L, Lu J, Sahle-Demessie E, Westenberg D, Yang H, Shi H) Anal Bioanal Chem 2024 Jan;416(2):419-430 PMID: 37962610 PMCID: PMC11077561 SCOPUS ID: 2-s2.0-85176598224 11/14/2023       5 Citations
  • Solubilization of chitosan in biologically relevant solvents by a low-temperature solvent-exchange method for developing biocompatible chitosan materials. (Li B, Qiu L, Zhang J, Liu S, Xu M, Wang J, Yang H) Int J Biol Macromol 2024 Jan;254(Pt 3):127950 PMID: 37951431 PMCID: PMC10843559 SCOPUS ID: 2-s2.0-85177177901 11/12/2023       27 Citations
  • Fate and distribution of orally-ingested CeO2-nanoparticles based on a mouse model: Implication for human health. (Ma X, Wang X, Xu L, Shi H, Yang H, Landrock KK, Sharma VK, Chapkin RS) Soil Environ Health 2023 Jun;1(2) PMID: 37830053 PMCID: PMC10568217 SCOPUS ID: 2-s2.0-85181933812 10/13/2023       8 Citations
  • Dendrimer and dendrimer gel-derived drug delivery systems: Breaking bottlenecks of topical administration of glaucoma medications (Wang J, Li B, Kompella UB, Yang H) Medcomm Biomaterials and Applications March 2023;2(1) SCOPUS ID: 2-s2.0-85172726626 03/01/2023       33 Citations
  • SRA inhibition improves antitumor potency of antigen-targeted chaperone vaccine (Jie Qian, Xiaofei Yu, Zheng Liu, Jingyang Cai, Huanfa Yi, Masoud Manjili, Hu Yang, Chunqing Guo, Xiang-Yang Wang) Frontiers in Immunology 01/30/2023    
  • A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3. (Bhagwani AR, Ali M, Piper B, Liu M, Hudson J, Kelly N, Bogamuwa S, Yang H, Londino JD, Bednash JS, Farkas D, Mallampalli RK, Nicolls MR, Ryan JJ, Thompson AAR, Chan SY, Gomez D, Goncharova EA, Farkas L) iScience 2023 Feb 17;26(2):105935 PMID: 36685041 PMCID: PMC9852960 SCOPUS ID: 2-s2.0-85146292305 01/24/2023       15 Citations
  • A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3 (Aneel R. Bhagwani, Mehboob Ali, Hu Yang, James D. Londino, Joseph S. Bednash, Daniela Farkas, Rama K. Mallampalli, Mark R. Nicolls, John J. Ryan, A.A. Roger Thompson, Elena A. Goncharova, Laszlo Farkas) iScience 01/05/2023    
  • Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and enhanced macrophage-targeted drug delivery (He J, Zhang W, Zhou X, Xu F, Zou J, Zhang Q, Zhao Y, He H, Yang H, Liu J) Bioactive Materials January 2023;19:115-126 SCOPUS ID: 2-s2.0-85127618720 01/01/2023       102 Citations
  • Uptake of Engineered Metallic Nanoparticles in Soil by Lettuce in Single and Binary Nanoparticle Systems (Xu L, Wang X, Shi H, Hua B, Burken JG, Ma X, Yang H, Yang JJ) ACS Sustainable Chemistry and Engineering 19 December 2022;10(50):16692-16700 SCOPUS ID: 2-s2.0-85143880360 12/19/2022       15 Citations
  • Ionic Liquid Pilocarpine Analog as an Antiglaucoma Drug Candidate. (Wang J, Li B, Tang J, Qiu L, Qiao X, Xu N, Yang H) ACS Pharmacol Transl Sci 2022 Sep 09;5(9):752-760 PMID: 36110370 PMCID: PMC9469494 SCOPUS ID: 2-s2.0-85138247763 09/17/2022       7 Citations
  • Engineering nanostructured pure cancer cell membrane-derived vesicles as a novel therapeutic cancer vaccine (He H, Guo C, Liu W, Chen S, Wang XY, Yang H) Medcomm Biomaterials and Applications September 2022;1(2) SCOPUS ID: 2-s2.0-85178201975 09/01/2022       11 Citations
  • Glycyrrhetinic acid-cyclodextrin grafted pullulan nanoparticles loaded doxorubicin as a liver targeted delivery carrier. (Yang W, Zhang Y, Wang J, Li H, Yang H) Int J Biol Macromol 2022 Sep 01;216:789-798 PMID: 35914549 SCOPUS ID: 2-s2.0-85135517704 08/02/2022       32 Citations
  • Dendrimer-based drug delivery systems: history, challenges, and latest developments. (Wang J, Li B, Qiu L, Qiao X, Yang H) J Biol Eng 2022 Jul 25;16(1):18 PMID: 35879774 PMCID: PMC9317453 SCOPUS ID: 2-s2.0-85134732898 07/26/2022       345 Citations
  • Clickable biocompatible brush polymers as a versatile platform toward development of multifunctional drug delivery vehicles (Huang D, Valerie K, Yang H) Reactive and Functional Polymers January 2022;170 SCOPUS ID: 2-s2.0-85124270706 01/01/2022    
  • Nano-in-Nano dendrimer gel particles for efficient topical delivery of antiglaucoma drugs into the eye (Wang J, Li B, Huang D, Norat P, Grannonico M, Cooper RC, Gui Q, Nam Chow W, Liu X, Yang H) Chemical Engineering Journal 1 December 2021;425 SCOPUS ID: 2-s2.0-85107310309 12/01/2021       73 Citations
  • Kidney-Targeted Delivery of Prolyl Hydroxylase Domain Protein 2 Small Interfering RNA with Nanoparticles Alleviated Renal Ischemia/Reperfusion Injury. (Xie D, Wang J, Hu G, Chen C, Yang H, Ritter JK, Qu Y, Li N) J Pharmacol Exp Ther 2021 Sep;378(3):235-243 PMID: 34103333 PMCID: PMC11047054 SCOPUS ID: 2-s2.0-85116958627 06/10/2021       19 Citations
  • Advanced Hydrogel Formulations for the Eye (Yang H) AAPS Advances in the Pharmaceutical Sciences Series 2021;37:449-462 SCOPUS ID: 2-s2.0-85124506006 01/01/2021    
  • Self-Assembly of pH-Labile Polymer Nanoparticles for Paclitaxel Prodrug Delivery: Formulation, Characterization, and Evaluation. (Levit SL, Gade NR, Roper TD, Yang H, Tang C) Int J Mol Sci 2020 Dec 05;21(23) PMID: 33291475 PMCID: PMC7730096 SCOPUS ID: 2-s2.0-85097372644 12/10/2020       18 Citations
  • "Double-punch" strategy for delivery of viral immunotherapy with prolonged tumor retention and enhanced transfection efficacy. (Wang J, Guo C, Wang XY, Yang H) J Control Release 2021 Jan 10;329:328-336 PMID: 33278479 PMCID: PMC7904666 SCOPUS ID: 2-s2.0-85097716937 12/06/2020       17 Citations
  • Drug-loaded chitosan film prepared via facile solution casting and air-drying of plain water-based chitosan solution for ocular drug delivery (Li B, Wang J, Gui Q, Yang H) Bioactive Materials September 2020;5(3):577-583 SCOPUS ID: 2-s2.0-85084144665 09/01/2020       127 Citations
  • Nanoparticle-based "Two-pronged" approach to regress atherosclerosis by simultaneous modulation of cholesterol influx and efflux. (He H, Wang J, Yannie PJ, Korzun WJ, Yang H, Ghosh S) Biomaterials 2020 Nov;260:120333 PMID: 32853832 PMCID: PMC7530139 SCOPUS ID: 2-s2.0-85089733138 08/28/2020       43 Citations
  • Polyamidoamine Dendrimer Grafted with an Acid-Responsive Charge-Reversal Layer for Improved Gene Delivery. (Wang J, Cooper RC, Yang H) Biomacromolecules 2020 Oct 12;21(10):4008-4016 PMID: 32820887 PMCID: PMC7583228 SCOPUS ID: 2-s2.0-85092803485 08/22/2020       20 Citations
  • Continuous production of uniform chitosan beads as hemostatic dressings by a facile flow injection method. (Li B, Wang J, Gui Q, Yang H) J Mater Chem B 2020 Sep 21;8(35):7941-7946 PMID: 32749422 SCOPUS ID: 2-s2.0-85091191271 08/05/2020       23 Citations
  • Duplex of Polyamidoamine Dendrimer/Custom-Designed Nuclear-Localization Sequence Peptide for Enhanced Gene Delivery (Cooper RC, Yang H) Bioelectricity June 2020;2(2):150-157 SCOPUS ID: 2-s2.0-85116540404 06/01/2020       8 Citations
  • Self-assembled block polymer aggregates in selective solution: controllable morphology transitions and their applications in drug delivery. (Jiao W, Yang H, Wu Z, Liu J, Zhang W) Expert Opin Drug Deliv 2020 Jul;17(7):947-961 PMID: 32441156 SCOPUS ID: 2-s2.0-85085605216 05/23/2020       29 Citations
  • Rapid self-assembly of polymer nanoparticles for synergistic codelivery of paclitaxel and lapatinib via flash nanoprecipitation (Levit SL, Yang H, Tang C) Nanomaterials March 2020;10(3):1-17 SCOPUS ID: 2-s2.0-85082675149 03/01/2020       36 Citations
  • PEAMOtecan, a novel chronotherapeutic polymeric drug for brain cancer. (Allen J, Wang J, Zolotarskaya OY, Sule A, Mohammad S, Arslan S, Wynne KJ, Yang H, Valerie K) J Control Release 2020 May 10;321:36-48 PMID: 32027939 PMCID: PMC8105881 SCOPUS ID: 2-s2.0-85079088007 02/07/2020       7 Citations
  • Injectable Multicomponent Biomimetic Gel Composed of Inter-Crosslinked Dendrimeric and Mesoporous Silica Nanoparticles Exhibits Highly Tunable Elasticity and Dual Drug Release Capacity. (Wang J, Li B, Pu X, Wang X, Cooper RC, Gui Q, Yang H) ACS Appl Mater Interfaces 2020 Mar 04;12(9):10202-10210 PMID: 32023033 PMCID: PMC10983814 SCOPUS ID: 2-s2.0-85080056781 02/06/2020       26 Citations
  • Ecofriendly Method to Dissolve Chitosan in Plain Water. (Li B, Wang J, Moustafa ME, Yang H) ACS Biomater Sci Eng 2019 Dec 09;5(12):6355-6360 PMID: 33417810 SCOPUS ID: 2-s2.0-85075174563 12/09/2019       26 Citations
  • Electrospun gelatin–arabinoxylan ferulate composite fibers for diabetic chronic wound dressing application (Aduba DC, An SS, Selders GS, Yeudall WA, Bowlin GL, Kitten T, Yang H) International Journal of Polymeric Materials and Polymeric Biomaterials 24 July 2019;68(11):660-668 SCOPUS ID: 2-s2.0-85049795752 07/24/2019       23 Citations
  • Dynamically enhancing plaque targeting via a positive feedback loop using multifunctional biomimetic nanoparticles for plaque regression. (Jiang C, Qi Z, He W, Li Z, Tang Y, Wang Y, Huang Y, Zang H, Yang H, Liu J) J Control Release 2019 Aug 28;308:71-85 PMID: 31295543 SCOPUS ID: 2-s2.0-85068902207 07/12/2019       63 Citations
  • Hydrogel-based ocular drug delivery systems: Emerging fabrication strategies, applications, and bench-to-bedside manufacturing considerations. (Cooper RC, Yang H) J Control Release 2019 Jul 28;306:29-39 PMID: 31128143 PMCID: PMC6629478 SCOPUS ID: 2-s2.0-85066247684 05/28/2019       172 Citations
  • Folate-Decorated Polyamidoamine Dendrimer Nanoparticles for Head and Neck Cancer Gene Therapy. (Xu L, Yang H) Methods Mol Biol 2019;1974:393-408 PMID: 31099016 SCOPUS ID: 2-s2.0-85066119747 05/18/2019       15 Citations
  • Drug-Conjugated Dendrimer Hydrogel Enables Sustained Drug Release via a Self-Cleaving Mechanism. (Wang J, He H, Cooper RC, Gui Q, Yang H) Mol Pharm 2019 May 06;16(5):1874-1880 PMID: 30974947 PMCID: PMC10958997 SCOPUS ID: 2-s2.0-85065441357 04/13/2019       30 Citations
  • Correction to "ATP-Responsive Low-Molecular-Weight Polyethylenimine-Based Supramolecular Assembly via Host-Guest Interaction for Gene Delivery". (Jiang C, Qi Z, Jia H, Huang Y, Wang Y, Zhang W, Wu Z, Yang H, Liu J) Biomacromolecules 2019 Feb 11;20(2):1132-1133 PMID: 30698010 SCOPUS ID: 2-s2.0-85061249004 01/31/2019       2 Citations
  • Targeted inactivation of EPS8 using dendrimer-mediated delivery of RNA interference. (Yuan Q, Yeudall WA, Lee E, Yang H) Int J Pharm 2019 Feb 25;557:178-181 PMID: 30597261 PMCID: PMC10629616 SCOPUS ID: 2-s2.0-85059532457 01/01/2019       6 Citations
  • Aza-michael addition cross-linking strategy for formation of dendrimer hydrogels, micro/nanogels, and cryogels (Wang J, Yang H) Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium 2019;40:276 SCOPUS ID: 2-s2.0-85065388652 01/01/2019    
  • Improving poly(Amidoamine) dendrimer gene delivery via physical interaction with a nuclear localization sequence peptide (Cooper RC, Yang H) Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium 2019;40:574 SCOPUS ID: 2-s2.0-85065415502 01/01/2019    
  • Targeted drug delivery via cell-nanoparticle hybridization for enhanced efficacy and reduced off-target toxicity (Cooper RC, Wang J, Yang H) Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium 2019;40:509 SCOPUS ID: 2-s2.0-85065410686 01/01/2019    
  • A hybrid dendrimer hydrogel as bone tuberculosis defect scaffold for regeneration and chemotherapy (Wang J, Cooper RC, Li B, Yang H) Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium 2019;40:926 SCOPUS ID: 2-s2.0-85065446623 01/01/2019    
  • ATP-Responsive Low-Molecular-Weight Polyethylenimine-Based Supramolecular Assembly via Host-Guest Interaction for Gene Delivery. (Jiang C, Qi Z, Jia H, Huang Y, Wang Y, Zhang W, Wu Z, Yang H, Liu J) Biomacromolecules 2019 Jan 14;20(1):478-489 PMID: 30516950 SCOPUS ID: 2-s2.0-85058880227 12/06/2018       41 Citations
  • Leutusome: A Biomimetic Nanoplatform Integrating Plasma Membrane Components of Leukocytes and Tumor Cells for Remarkably Enhanced Solid Tumor Homing. (He H, Guo C, Wang J, Korzun WJ, Wang XY, Ghosh S, Yang H) Nano Lett 2018 Oct 10;18(10):6164-6174 PMID: 30207473 PMCID: PMC6292712 SCOPUS ID: 2-s2.0-85053697509 09/13/2018       152 Citations
  • Polyamidoamine Dendrimer Microgels: Hierarchical Arrangement of Dendrimers into Micrometer Domains with Expanded Structural Features for Programmable Drug Delivery and Release (Wang J, Cooper RC, He H, Li B, Yang H) Macromolecules 14 August 2018;51(15):6111-6118 SCOPUS ID: 2-s2.0-85051503574 08/14/2018       37 Citations
  • Cholangiocyte-derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and humans (Xiaojiaoyang Li, Runping Liu, Zhiming Huang, Emily C. Gurley, Xuan Wang, Juan Wang, Hongliang He, Hu Yang, Guanghua Lai, Luyong Zhang, Jasmohan S Bajaj, Melanie White, William M Pandak, Phillip B. Hylemon, and Huiping Zhou) Hepatology 08/01/2018    
  • Folate-Targeted Redox-Responsive Polymersomes Loaded with Chemotherapeutic Drugs and Tariquidar to Overcome Drug Resistance. (Qin Y, Zhang Z, Huang C, Fan F, Liu L, Lu L, Wang H, Liu Z, Yang J, Wang C, Yang H, Sun H, Leng X, Kong D, Zhang L, Zhu D) J Biomed Nanotechnol 2018 Oct 01;14(10):1705-1718 PMID: 30041718 SCOPUS ID: 2-s2.0-85053638219 07/26/2018       26 Citations
  • Co-delivery of LOX-1 siRNA and statin to endothelial cells and macrophages in the atherosclerotic lesions by a dual-targeting core-shell nanoplatform: A dual cell therapy to regress plaques. (Zhao Y, Gao H, He J, Jiang C, Lu J, Zhang W, Yang H, Liu J) J Control Release 2018 Aug 10;283:241-260 PMID: 29885417 SCOPUS ID: 2-s2.0-85048348652 06/10/2018       72 Citations
  • Bubble-generating polymersomes loaded with both indocyanine green and doxorubicin for effective chemotherapy combined with photothermal therapy. (Zhu D, Fan F, Huang C, Zhang Z, Qin Y, Lu L, Wang H, Jin X, Zhao H, Yang H, Zhang C, Yang J, Liu Z, Sun H, Leng X, Kong D, Zhang L) Acta Biomater 2018 Jul 15;75:386-397 PMID: 29793073 SCOPUS ID: 2-s2.0-85048564792 05/25/2018       58 Citations
  • DenTimol as A Dendrimeric Timolol Analogue for Glaucoma Therapy: Synthesis and Preliminary Efficacy and Safety Assessment. (Lancina MG 3rd, Wang J, Williamson GS, Yang H) Mol Pharm 2018 Jul 02;15(7):2883-2889 PMID: 29767982 PMCID: PMC6075655 SCOPUS ID: 2-s2.0-85047385960 05/17/2018       36 Citations
  • Superelastic and pH-Responsive Degradable Dendrimer Cryogels Prepared by Cryo-aza-Michael Addition Reaction. (Wang J, Yang H) Sci Rep 2018 May 08;8(1):7155 PMID: 29740011 PMCID: PMC5940921 SCOPUS ID: 2-s2.0-85046840298 05/10/2018       33 Citations
  • Mildly Cross-Linked Dendrimer Hydrogel Prepared via Aza-Michael Addition Reaction for Topical Brimonidine Delivery. (Wang J, Williamson GS, Lancina Iii MG, Yang H) J Biomed Nanotechnol 2017 Dec;13(9):1089-1096 PMID: 29479294 PMCID: PMC5819351 SCOPUS ID: 2-s2.0-85038826979 02/27/2018       35 Citations
  • Branched polyrotaxane hydrogels consisting of alpha-cyclodextrin and low-molecular-weight four-arm polyethylene glycol and the utility of their thixotropic property for controlled drug release. (Wang J, Williamson GS, Yang H) Colloids Surf B Biointerfaces 2018 May 01;165:144-149 PMID: 29476924 PMCID: PMC5882578 SCOPUS ID: 2-s2.0-85042385739 02/25/2018       49 Citations
  • Biomimetic Composite Scaffold Containing Small Intestinal Submucosa and Mesoporous Bioactive Glass Exhibits High Osteogenic and Angiogenic Capacity. (Sun T, Liu M, Yao S, Ji Y, Xiong Z, Tang K, Chen K, Yang H, Guo X) Tissue Eng Part A 2018 Jul;24(13-14):1044-1056 PMID: 29350101 SCOPUS ID: 2-s2.0-85049621857 01/20/2018       30 Citations
  • Development of mannose functionalized dendrimeric nanoparticles for targeted delivery to macrophages: use of this platform to modulate atherosclerosis. (He H, Yuan Q, Bie J, Wallace RL, Yannie PJ, Wang J, Lancina MG 3rd, Zolotarskaya OY, Korzun W, Yang H, Ghosh S) Transl Res 2018 Mar;193:13-30 PMID: 29172034 PMCID: PMC6198660 SCOPUS ID: 2-s2.0-85035193608 11/25/2017       99 Citations
  • Erratum: Chitosan nanofibers for transbuccal insulin delivery. (Lancina MG 3rd, Shankar RK, Yang H) J Biomed Mater Res A 2017 Dec;105(12):3520 PMID: 29077276 SCOPUS ID: 2-s2.0-85032281757 10/28/2017    
  • Synthesis of regioselectively acylated quercetin analogues with improved antiplatelet activity. (Duan Y, Sun N, Xue M, Wang X, Yang H) Mol Med Rep 2017 Dec;16(6):9735-9740 PMID: 29039540 SCOPUS ID: 2-s2.0-85032742406 10/19/2017       26 Citations
  • Evaluation of osteogenic inductivity of a novel BMP2-mimicking peptide P28 and P28-containing bone composite. (Sun T, Qu Y, Cui W, Yang L, Ji Y, Yu W, Navinduth R, Shao Z, Yang H, Guo X) J Biomed Mater Res A 2018 Jan;106(1):210-220 PMID: 28884509 SCOPUS ID: 2-s2.0-85035083091 09/09/2017       23 Citations
  • Pediatric ocular nanomedicines: Challenges and opportunities (Sheybani ND, Yang H) Chinese Chemical Letters September 2017;28(9):1817-1821 SCOPUS ID: 2-s2.0-85027262164 09/01/2017       21 Citations
  • Fast Dissolving Dendrimer Nanofiber Mats as Alternative to Eye Drops for More Efficient Antiglaucoma Drug Delivery (Lancina MG, Singh S, Kompella UB, Husain S, Yang H) ACS Biomaterials Science and Engineering 14 August 2017;3(8):1861-1868 SCOPUS ID: 2-s2.0-85027250140 08/14/2017       86 Citations
  • Synthesis and Application of Injectable Bioorthogonal Dendrimer Hydrogels for Local Drug Delivery (Xu L, Cooper RC, Wang J, Yeudall WA, Yang H) ACS Biomaterials Science and Engineering 14 August 2017;3(8):1641-1653 SCOPUS ID: 2-s2.0-85027244722 08/14/2017       38 Citations
  • Folic acid-decorated polyamidoamine dendrimer exhibits high tumor uptake and sustained highly localized retention in solid tumors: Its utility for local siRNA delivery. (Xu L, Yeudall WA, Yang H) Acta Biomater 2017 Jul 15;57:251-261 PMID: 28438704 PMCID: PMC5555737 SCOPUS ID: 2-s2.0-85018794976 04/26/2017       64 Citations
  • Bolstering cholesteryl ester hydrolysis in liver: A hepatocyte-targeting gene delivery strategy for potential alleviation of atherosclerosis. (He H, Lancina MG 3rd, Wang J, Korzun WJ, Yang H, Ghosh S) Biomaterials 2017 Jun;130:1-13 PMID: 28349866 PMCID: PMC5560268 SCOPUS ID: 2-s2.0-85016083493 03/30/2017       34 Citations
  • In Situ-Forming Polyamidoamine Dendrimer Hydrogels with Tunable Properties Prepared via Aza-Michael Addition Reaction. (Wang J, He H, Cooper RC, Yang H) ACS Appl Mater Interfaces 2017 Mar 29;9(12):10494-10503 PMID: 28263553 PMCID: PMC5818279 SCOPUS ID: 2-s2.0-85016620438 03/07/2017       70 Citations
  • Polysaccharide fabrication platforms and biocompatibility assessment as candidate wound dressing materials (Aduba DC, Yang H) Bioengineering March 2017;4(1) SCOPUS ID: 2-s2.0-85050922277 03/01/2017       123 Citations
  • Folate-mediated chemotherapy and diagnostics: An updated review and outlook. (Xu L, Bai Q, Zhang X, Yang H) J Control Release 2017 Apr 28;252:73-82 PMID: 28235591 PMCID: PMC5479736 SCOPUS ID: 2-s2.0-85015451755 02/27/2017       110 Citations
  • Nanoconjugated NAP as a potent and periphery selective Mu opioid receptor modulator to treat opioid-induced constipation (Xu GG, Zolotarskaya OY, Williams DA, Yuan Y, Selley DE, Dewey WL, Akbarali HI, Yang H, Zhang Y) ACS Medicinal Chemistry Letters 12 January 2017;8(1):78-83 SCOPUS ID: 2-s2.0-85020884536 01/12/2017       5 Citations
  • Nanomedicines for dysfunctional macrophage-associated diseases. (He H, Ghosh S, Yang H) J Control Release 2017 Feb 10;247:106-126 PMID: 28057522 PMCID: PMC5360184 SCOPUS ID: 2-s2.0-85008877575 01/07/2017       49 Citations
  • Dendrimers for ocular drug delivery (Lancina MG, Yang H) Canadian Journal of Chemistry 2017;95(9):897-902 SCOPUS ID: 2-s2.0-85028593416 01/01/2017       69 Citations
  • Chitosan nanofibers for transbuccal insulin delivery. (Lancina MG 3rd, Shankar RK, Yang H) J Biomed Mater Res A 2017 May;105(5):1252-1259 PMID: 28000386 PMCID: PMC5378649 SCOPUS ID: 2-s2.0-85012256187 12/22/2016       60 Citations
  • Folic acid-decorated polyamidoamine dendrimer mediates selective uptake and high expression of genes in head and neck cancer cells. (Xu L, Kittrell S, Yeudall WA, Yang H) Nanomedicine (Lond) 2016 Nov;11(22):2959-2973 PMID: 27781559 PMCID: PMC5144492 SCOPUS ID: 2-s2.0-84994641761 11/01/2016       40 Citations
  • Fabrication, characterization, and in vitro evaluation of silver-containing arabinoxylan foams as antimicrobial wound dressing. (Aduba DC Jr, An SS, Selders GS, Wang J, Andrew Yeudall W, Bowlin GL, Kitten T, Yang H) J Biomed Mater Res A 2016 Oct;104(10):2456-65 PMID: 27199211 PMCID: PMC5108242 SCOPUS ID: 2-s2.0-84983657288 05/21/2016       16 Citations
  • Dendrimers in drug delivery (Yang H) Colloids in Drug Delivery 19 April 2016:435-454 SCOPUS ID: 2-s2.0-85033680107 04/19/2016       2 Citations
  • Targeted nanosystems: Advances in targeted dendrimers for cancer therapy. (Yang H) Nanomedicine 2016 Feb;12(2):309-16 PMID: 26706410 PMCID: PMC4789125 SCOPUS ID: 2-s2.0-84954290101 12/27/2015       86 Citations
  • Micro-channel diffusion characteristics of an implantable drug delivery device for age-related macular degeneration (Pidaparti RM, Lee JH, Yang H) Microsystem Technologies 21 September 2015;21(9):1967-1974 SCOPUS ID: 2-s2.0-85027944475 09/21/2015       2 Citations
  • Dendrimer-enabled transformation of Anaplasma phagocytophilum. (Oki AT, Seidman D, Lancina MG 3rd, Mishra MK, Kannan RM, Yang H, Carlyon JA) Microbes Infect 2015;17(11-12):817-22 PMID: 26369714 PMCID: PMC4666749 SCOPUS ID: 2-s2.0-84944112180 09/16/2015       10 Citations
  • Electrospinning of PEGylated polyamidoamine dendrimer fibers. (Aduba DC Jr, Overlin JW, Frierson CD, Bowlin GL, Yang H) Mater Sci Eng C Mater Biol Appl 2015 Nov 01;56:189-94 PMID: 26249580 PMCID: PMC4552351 SCOPUS ID: 2-s2.0-84934984341 08/08/2015       10 Citations
  • Click synthesis of a polyamidoamine dendrimer-based camptothecin prodrug (Olga Yu Zolotarskaya, Leyuan Xu, Kristoffer Valerie, Hu Yang) RSC Advances 06/29/2015    
  • The effect of photoinitiators on intracellular AKT signaling pathway in tissue engineering application. (Xu L, Sheybani N, Yeudall WA, Yang H) Biomater Sci 2015 Feb;3(2):250-5 PMID: 25709809 PMCID: PMC4335638 SCOPUS ID: 2-s2.0-84921649940 02/25/2015       52 Citations
  • Semi-interpenetrating network (sIPN) co-electrospun gelatin/insulin fiber formulation for transbuccal insulin delivery. (Xu L, Sheybani N, Ren S, Bowlin GL, Yeudall WA, Yang H) Pharm Res 2015 Jan;32(1):275-85 PMID: 25030186 SCOPUS ID: 2-s2.0-84934759151 07/18/2014       39 Citations
  • Thermoresponsive Dendritic Facial Amphiphiles for Gene Delivery (Quan Yuan, W. Andrew Yeudall, Hu Yang) Nanomedicine and Nanobiology 06/01/2014    
  • Click hybridization of immune cells and polyamidoamine dendrimers. (Xu L, Zolotarskaya OY, Yeudall WA, Yang H) Adv Healthc Mater 2014 Sep;3(9):1430-8 PMID: 24574321 PMCID: PMC4133313 SCOPUS ID: 2-s2.0-84908018516 02/28/2014       27 Citations
  • Revisiting p53 for cancer-specific chemo- and radiotherapy: ten years after. (Beckta JM, Ahmad SF, Yang H, Valerie K) Cell Cycle 2014;13(5):710-3 PMID: 24526114 PMCID: PMC3979907 SCOPUS ID: 2-s2.0-84897969159 02/15/2014       33 Citations
  • Electrospun blends of gelatin and gelatin-dendrimer conjugates as a wound-dressing and drug-delivery platform. (Dongargaonkar AA, Bowlin GL, Yang H) Biomacromolecules 2013 Nov 11;14(11):4038-45 PMID: 24127747 PMCID: PMC3886127 SCOPUS ID: 2-s2.0-84887596175 10/17/2013       91 Citations
  • Semi-interpenetrating network (sIPN) gelatin nanofiber scaffolds for oral mucosal drug delivery. (Aduba DC Jr, Hammer JA, Yuan Q, Yeudall WA, Bowlin GL, Yang H) Acta Biomater 2013 May;9(5):6576-84 PMID: 23416578 PMCID: PMC3622783 SCOPUS ID: 2-s2.0-84879889647 02/19/2013       81 Citations
  • Synthesis and characterization of clickable cytocompatible poly(ethylene glycol)-grafted polyoxetane brush polymers (Zolotarskaya OY, Yuan Q, Wynne KJ, Yang H) Macromolecules 8 January 2013;46(1):63-71 SCOPUS ID: 2-s2.0-84872110755 01/08/2013       18 Citations
  • Dendrimer-based RNA interference delivery for cancer therapy (Xu L, Andrew Yeudall W, Yang H) ACS Symposium Series July 8, 2013;1135:197-213 SCOPUS ID: 2-s2.0-84905397389 01/01/2013       12 Citations
  • Hybrid dendrimer hydrogel/poly(lactic-co-glycolic acid) nanoparticle platform: an advanced vehicle for topical delivery of antiglaucoma drugs and a likely solution to improving compliance and adherence in glaucoma management. (Yang H, Leffler CT) J Ocul Pharmacol Ther 2013 Mar;29(2):166-72 PMID: 23249385 SCOPUS ID: 2-s2.0-84875017022 12/20/2012       34 Citations
  • Poly(ethylene glycol)-armed hyperbranched polyoxetanes for anticancer drug delivery (Sharma K, Zolotarskaya OY, Wynne KJ, Yang H) Journal of Bioactive and Compatible Polymers November 2012;27(6):525-539 SCOPUS ID: 2-s2.0-84869006303 11/01/2012       17 Citations
  • Synthesis of water-soluble camptothecin-polyoxetane conjugates via click chemistry. (Zolotarskaya OY, Wagner AF, Beckta JM, Valerie K, Wynne KJ, Yang H) Mol Pharm 2012 Nov 05;9(11):3403-8 PMID: 23051100 PMCID: PMC3496795 SCOPUS ID: 2-s2.0-84868524364 10/12/2012       27 Citations
  • Mineralization potential of electrospun PDO-hydroxyapatite-fibrinogen blended scaffolds (Rodriguez IA, Madurantakam PA, McCool JM, Sell SA, Yang H, Moon PC, Bowlin GL) International Journal of Biomaterials 2012 SCOPUS ID: 2-s2.0-84866258763 09/19/2012       27 Citations
  • Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration. (Yang H, Tyagi P, Kadam RS, Holden CA, Kompella UB) ACS Nano 2012 Sep 25;6(9):7595-606 PMID: 22876910 SCOPUS ID: 2-s2.0-84866656642 08/11/2012       188 Citations
  • A pro-convulsive carbamazepine metabolite: quinolinic acid in drug resistant epileptic human brain. (Ghosh C, Marchi N, Hossain M, Rasmussen P, Alexopoulos AV, Gonzalez-Martinez J, Yang H, Janigro D) Neurobiol Dis 2012 Jun;46(3):692-700 PMID: 22426401 PMCID: PMC4001854 SCOPUS ID: 2-s2.0-84860838360 03/20/2012       26 Citations
  • Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents. (Biddlestone-Thorpe L, Marchi N, Guo K, Ghosh C, Janigro D, Valerie K, Yang H) Adv Drug Deliv Rev 2012 May 15;64(7):605-13 PMID: 22178615 PMCID: PMC3321130 SCOPUS ID: 2-s2.0-84859979641 12/20/2011       109 Citations
  • Transbuccal delivery of CNS therapeutic nanoparticles: Synthesis, characterization, and in vitro permeation studies (Yuan Q, Fu Y, Kao WJ, Janigro D, Yang H) ACS Chemical Neuroscience 16 November 2011;2(11):676-683 SCOPUS ID: 2-s2.0-81455136017 11/16/2011       40 Citations
  • Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs. (Holden CA, Tyagi P, Thakur A, Kadam R, Jadhav G, Kompella UB, Yang H) Nanomedicine 2012 Jul;8(5):776-83 PMID: 21930109 SCOPUS ID: 2-s2.0-84862645239 09/21/2011       133 Citations
  • Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery. (Yuan Q, Lee E, Yeudall WA, Yang H) Oral Oncol 2010 Sep;46(9):698-704 PMID: 20729136 PMCID: PMC2938769 SCOPUS ID: 2-s2.0-77956394256 08/24/2010       60 Citations
  • PEGylated polyamidoamine dendrimers with bis-aryl hydrazone linkages for enhanced gene delivery. (Yuan Q, Yeudall WA, Yang H) Biomacromolecules 2010 Aug 09;11(8):1940-7 PMID: 20593893 PMCID: PMC2918678 SCOPUS ID: 2-s2.0-77955579970 07/03/2010       86 Citations
  • Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis. (Yang H) Pharm Res 2010 Sep;27(9):1759-71 PMID: 20593303 PMCID: PMC2933363 SCOPUS ID: 2-s2.0-77955466238 07/02/2010       204 Citations
  • Surface engineering of macrophages with nanoparticles to generate a cell-nanoparticle hybrid vehicle for hypoxia-targeted drug delivery. (Holden CA, Yuan Q, Yeudall WA, Lebman DA, Yang H) Int J Nanomedicine 2010 Feb 02;5:25-36 PMID: 20161985 PMCID: PMC2819902 SCOPUS ID: 2-s2.0-77951188983 02/18/2010       74 Citations
  • Synthesis and characterization of photocurable polyamidoamine dendrimer hydrogels as a versatile platform for tissue engineering and drug delivery. (Desai PN, Yuan Q, Yang H) Biomacromolecules 2010 Mar 08;11(3):666-73 PMID: 20108892 PMCID: PMC2849659 SCOPUS ID: 2-s2.0-77950171559 01/30/2010       77 Citations
  • Synthesis and characterization of thermoresponsive polyamidoamine-polyethylene glycol-poly(D,L-lactide) core-shell nanoparticles. (Kailasan A, Yuan Q, Yang H) Acta Biomater 2010 Mar;6(3):1131-9 PMID: 19716444 PMCID: PMC2815164 SCOPUS ID: 2-s2.0-75149197230 09/01/2009       36 Citations
  • Synthesis and characterization of a novel dendrimer-based thermoresponsive core-shell nanoparticle for drug delivery (Kailasan A, Yang H) Materials Research Society Symposium Proceedings 2008;1095:20-24 SCOPUS ID: 2-s2.0-70350266540 12/01/2008    
  • Encapsulation and extended release of anti-cancer anastrozole by stealth nanoparticles. (Sarkar K, Yang H) Drug Deliv 2008 Jun;15(5):343-6 PMID: 18763165 SCOPUS ID: 2-s2.0-50849109488 09/03/2008       48 Citations
  • Synthesis and characterization of photocurable polyionic hydrogels (Desai PN, Yang H) Materials Research Society Symposium Proceedings 2008;1095:36-39 SCOPUS ID: 2-s2.0-70350289950 01/01/2008       3 Citations
  • A novel electrospun dendrimer-gelatin hybrid nanofiber scaffold for tissue regeneration and drug delivery (Smith-Freshwater AP, Bowlin GL, Yang H) Materials Research Society Symposium Proceedings 2008;1094:87-91 SCOPUS ID: 2-s2.0-77957955648 01/01/2008       8 Citations
  • Stealth dendrimers for drug delivery: correlation between PEGylation, cytocompatibility, and drug payload. (Yang H, Lopina ST, DiPersio LP, Schmidt SP) J Mater Sci Mater Med 2008 May;19(5):1991-7 PMID: 17952565 SCOPUS ID: 2-s2.0-41049095418 10/24/2007       79 Citations
  • Synthesis and characterization of nanoscale dendritic RGD clusters for potential applications in tissue engineering and drug delivery (Hu Yang, Weiyuan John Kao) International Journal of Nanomedicine 10/15/2007    
  • Stealth dendrimers for antiarrhythmic quinidine delivery. (Yang H, Lopina ST) J Mater Sci Mater Med 2007 Oct;18(10):2061-5 PMID: 17558476 SCOPUS ID: 2-s2.0-34548748110 06/15/2007       30 Citations
  • Dendrimers for pharmaceutical and biomedical applications. (Yang H, Kao WJ) J Biomater Sci Polym Ed 2006;17(1-2):3-19 PMID: 16411595 SCOPUS ID: 2-s2.0-33746077220 01/18/2006       176 Citations
  • In vitro enzymatic stability of dendritic peptides. (Yang H, Lopina ST) J Biomed Mater Res A 2006 Feb;76(2):398-407 PMID: 16270346 SCOPUS ID: 2-s2.0-33645102601 11/05/2005       28 Citations
  • Thermoresponsive gelatin/monomethoxy poly(ethylene glycol)-poly(D,L-lactide) hydrogels: formulation, characterization, and antibacterial drug delivery. (Yang H, Kao WJ) Pharm Res 2006 Jan;23(1):205-14 PMID: 16270162 SCOPUS ID: 2-s2.0-32244448545 11/05/2005       48 Citations
  • Extended release of a novel antidepressant, venlafaxine, based on anionic polyamidoamine dendrimers and poly(ethylene glycol)-containing semi-interpenetrating networks. (Yang H, Lopina ST) J Biomed Mater Res A 2005 Jan 01;72(1):107-14 PMID: 15543595 SCOPUS ID: 2-s2.0-10344222643 11/16/2004       74 Citations
  • Polyethylene glycol-polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in water. (Yang H, Morris JJ, Lopina ST) J Colloid Interface Sci 2004 May 01;273(1):148-54 PMID: 15051444 SCOPUS ID: 2-s2.0-1642502287 03/31/2004       178 Citations
  • Penicillin V-conjugated PEG-PAMAM star polymers. (Yang H, Lopina ST) J Biomater Sci Polym Ed 2003;14(10):1043-56 PMID: 14661878 SCOPUS ID: 2-s2.0-0242269078 12/10/2003       142 Citations
  • Polymeric dyes-synthesis, applications and prospects (Hu Yang, Puxin Zhu, Dacheng Wu) Dyestuffs and Coloration 12/01/2000    
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