Medical College of Wisconsin
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Jessica B. Wagenknecht

Jessica B. Wagenknecht profile photo picture

Bioinformatics Analyst II

Institution: Medical College of Wisconsin
Department: Mellowes Center for Genomic Sciences and Precision Medicine

Publications (7)

  • An Integrative Multitiered Computational Analysis for Better Understanding the Structure and Function of 85 Miniproteins. (Veluri R, Pollin G, Wagenknecht JB, Urrutia R, Zimmermann MT) bioRxiv 2025 Feb 05 PMID: 39974886 PMCID: PMC11838408 02/20/2025    
  • Discovery of a MET -driven monogenic cause of steatotic liver disease. (Pinto E Vairo F, Zimmermann MT, Wagenknecht J, Jorge SD, Tian S, Vierkant RA, Luehrs AC, Milech de Assunção T, Mathison A, Atwal PS, Cao Y, Allen AM, Klee EW, Urrutia R, Lazaridis KN) Hepatology 2025 Dec 01;82(6):1512-1522 PMID: 39879586 SCOPUS ID: 2-s2.0-85217105777 01/29/2025    
  • Systematic analysis of the relationship between fold-dependent flexibility and artificial intelligence protein structure prediction. (Haque N, Wagenknecht JB, Ratnasinghe BD, Zimmermann MT) PLoS One 2024;19(11):e0313308 PMID: 39591473 PMCID: PMC11594405 SCOPUS ID: 2-s2.0-85210375728 11/26/2024       1 Citation
  • Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction. (Jorge SD, Chi YI, Mazaba JL, Haque N, Wagenknecht J, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R) Front Genet 2023;14:1291307 PMID: 38090150 PMCID: PMC10715303 SCOPUS ID: 2-s2.0-85179362461 12/13/2023       4 Citations
  • RAG genomic variation causes autoimmune diseases through specific structure-based mechanisms of enzyme dysregulation. (Haque N, Kawai T, Ratnasinghe BD, Wagenknecht JB, Urrutia R, Notarangelo LD, Zimmermann MT) iScience 2023 Oct 20;26(10):108040 PMID: 37854700 PMCID: PMC10579426 SCOPUS ID: 2-s2.0-85174692439 10/19/2023       4 Citations
  • Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape. (Ratnasinghe BD, Haque N, Wagenknecht JB, Jensen DR, Valdivia Esparza GK, Leverence EN, Milech De Assuncao T, Mathison AJ, Lomberk G, Smith BC, Volkman BF, Urrutia R, Zimmermann MT) Comput Struct Biotechnol J 2023;21:4790-4803 PMID: 37841325 PMCID: PMC10570560 SCOPUS ID: 2-s2.0-85173171942 10/16/2023       8 Citations
  • Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape. (Ratnasinghe BD, Haque N, Wagenknecht JB, Jensen DR, Esparza GV, Leverence EN, De Assuncao TM, Mathison AJ, Lomberk G, Smith BC, Volkman BF, Urrutia R, Zimmermann MT) bioRxiv 2023 Apr 28 PMID: 37207265 PMCID: PMC10189839 05/19/2023    
    • Last update: 12/17/2025