Medical College of Wisconsin
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Jing Pan PhD

Jing Pan PhD profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Pharmacology and Toxicology
Program: Pharmacology

Member of the Cancer Center
Member of the Center for Disease Prevention Research (CDPR)


Publications (35)

  • Increased formation of reactive oxygen species during tumor growth: Ex vivo low-temperature EPR and in vivo bioluminescence analyses. (Cheng G, Pan J, Podsiadly R, Zielonka J, Garces AM, Dias Duarte Machado LG, Bennett B, McAllister D, Dwinell MB, You M, Kalyanaraman B) Free Radic Biol Med 2020 02 01;147:167-174 PMID: 31874251 PMCID: PMC6948008 SCOPUS ID: 2-s2.0-85076857582 12/25/2019       2 Citations
  • Potentiation of Kras peptide cancer vaccine by avasimibe, a cholesterol modulator. (Pan J, Zhang Q, Palen K, Wang L, Qiao L, Johnson B, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M) EBioMedicine 2019 Nov;49:72-81 PMID: 31680003 PMCID: PMC6945201 SCOPUS ID: 2-s2.0-85074132937 11/05/2019       2 Citations
  • Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis. (Cheng G, Zhang Q, Pan J, Lee Y, Ouari O, Hardy M, Zielonka M, Myers CR, Zielonka J, Weh K, Chang AC, Chen G, Kresty L, Kalyanaraman B, You M) Nat Commun 2019 05 17;10(1):2205 PMID: 31101821 PMCID: PMC6525201 SCOPUS ID: 2-s2.0-85065824371 05/19/2019       13 Citations
  • Optimized Bexarotene Aerosol Formulation Inhibits Major Subtypes of Lung Cancer in Mice. (Zhang Q, Lee SB, Chen X, Stevenson ME, Pan J, Xiong D, Zhou Y, Miller MS, Lubet RA, Wang Y, Mirza SP, You M) Nano Lett 2019 04 10;19(4):2231-2242 PMID: 30873838 SCOPUS ID: 2-s2.0-85063522412 03/16/2019       1 Citation
  • Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity. (Pan J, Lee Y, Cheng G, Zielonka J, Zhang Q, Bajzikova M, Xiong D, Tsaih SW, Hardy M, Flister M, Olsen CM, Wang Y, Vang O, Neuzil J, Myers CR, Kalyanaraman B, You M) iScience 2018 May 25;3:192-207 PMID: 30428319 PMCID: PMC6137433 11/15/2018    
  • Isolation and Characterization of a Chinese Hamster Ovary Heparan Sulfate Cell Mutant Defective in Both Met Receptor Binding and Hepatocyte Growth Factor NK1/Met Signaling. (Cao T, Pan J, Li X, He Y, Jiang Y, Chang Y, Zhang Q, Lan Y, Wang H, Jiao W, Tian Z, Zhang L) Cell Physiol Biochem 2018;48(4):1480-1491 PMID: 30107380 SCOPUS ID: 2-s2.0-85052205976 08/15/2018       1 Citation
  • Airway brushing as a new experimental methodology to detect airway gene expression signatures in mouse lung squamous cell carcinoma. (Pan J, Xiong D, Zhang Q, Szabo E, Miller MS, Lubet RA, Wang Y, You M) Sci Rep 2018 06 11;8(1):8895 PMID: 29891994 PMCID: PMC5995924 SCOPUS ID: 2-s2.0-85048432720 06/13/2018       1 Citation
  • Novel mutational landscapes and expression signatures of lung squamous cell carcinoma. (Xiong D, Pan J, Yin Y, Jiang H, Szabo E, Lubet RA, Wang Y, You M) Oncotarget 2018 Jan 26;9(7):7424-7441 PMID: 29484121 PMCID: PMC5800913 02/28/2018    
  • Immunoprevention of KRAS-driven lung adenocarcinoma by a multipeptide vaccine. (Pan J, Zhang Q, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M) Oncotarget 2017 Oct 10;8(47):82689-82699 PMID: 29137294 PMCID: PMC5669920 11/16/2017    
  • Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer. (Zhang Q, Li R, Chen X, Lee SB, Pan J, Xiong D, Hu J, Miller MS, Szabo E, Lubet RA, Wang Y, You M) Oncotarget 2017 Sep 22;8(42):72447-72456 PMID: 29069801 PMCID: PMC5641144 10/27/2017    
  • Pioglitazone-mediated reversal of elevated glucose metabolism in the airway epithelium of mouse lung adenocarcinomas. (Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, Wang Y, You M) JCI Insight 2017 Jul 06;2(13) PMID: 28679956 PMCID: PMC5499364 SCOPUS ID: 2-s2.0-85062389798 07/07/2017    
  • Rad52 deficiency decreases development of lung squamous cell carcinomas by enhancing immuno-surveillance. (Lieberman R, Pan J, Zhang Q, You M) Oncotarget 2017 May 23;8(21):34032-34044 PMID: 28415565 PMCID: PMC5470949 04/19/2017    
  • Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. (Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, You M, Wang Y) Oncotarget 2017 Mar 21;8(12):18885-18900 PMID: 27935865 PMCID: PMC5386655 12/10/2016    
  • Honokiol Decreases Lung Cancer Metastasis through Inhibition of the STAT3 Signaling Pathway. (Pan J, Lee Y, Zhang Q, Xiong D, Wan TC, Wang Y, You M) Cancer Prev Res (Phila) 2017 Feb;10(2):133-141 PMID: 27849557 PMCID: PMC6005650 SCOPUS ID: 2-s2.0-85012027149 11/17/2016       18 Citations
  • miR-375 induces docetaxel resistance in prostate cancer by targeting SEC23A and YAP1. (Wang Y, Lieberman R, Pan J, Zhang Q, Du M, Zhang P, Nevalainen M, Kohli M, Shenoy NK, Meng H, You M, Wang L) Mol Cancer 2016 11 10;15(1):70 PMID: 27832783 PMCID: PMC5105253 SCOPUS ID: 2-s2.0-84995489496 11/12/2016       57 Citations
  • Honokiol targets mitochondria to halt cancer progression and metastasis. (Pan J, Lee Y, Wang Y, You M) Mol Nutr Food Res 2016 06;60(6):1383-95 PMID: 27276215 SCOPUS ID: 2-s2.0-84973462458 06/09/2016       28 Citations
  • Enhanced antitumor activity of 3-bromopyruvate in combination with rapamycin in vivo and in vitro. (Zhang Q, Pan J, Lubet RA, Komas SM, Kalyanaraman B, Wang Y, You M) Cancer Prev Res (Phila) 2015 Apr;8(4):318-26 PMID: 25644152 PMCID: PMC6004825 SCOPUS ID: 2-s2.0-84927674589 02/04/2015       11 Citations
  • Dietary diindolylmethane suppresses inflammation-driven lung squamous cell carcinoma in mice. (Song JM, Qian X, Teferi F, Pan J, Wang Y, Kassie F) Cancer Prev Res (Phila) 2015 Jan;8(1):77-85 PMID: 25403850 PMCID: PMC4289649 SCOPUS ID: 2-s2.0-84920837736 11/19/2014       7 Citations
  • Honokiol inhibits lung tumorigenesis through inhibition of mitochondrial function. (Pan J, Zhang Q, Liu Q, Komas SM, Kalyanaraman B, Lubet RA, Wang Y, You M) Cancer Prev Res (Phila) 2014 Nov;7(11):1149-59 PMID: 25245764 PMCID: PMC6010030 SCOPUS ID: 2-s2.0-84910118566 09/24/2014       24 Citations
  • Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention. (Zhang Q, Pan J, Lubet RA, Wang Y, You M) Mol Carcinog 2015 Jun;54 Suppl 1:E129-37 PMID: 25163779 SCOPUS ID: 2-s2.0-84931025987 08/29/2014       14 Citations
  • Transcriptomic analysis by RNA-seq reveals AP-1 pathway as key regulator that green tea may rely on to inhibit lung tumorigenesis. (Pan J, Zhang Q, Xiong D, Vedell P, Yan Y, Jiang H, Cui P, Ding F, Tichelaar JW, Wang Y, Lubet RA, You M) Mol Carcinog 2014 Jan;53(1):19-29 PMID: 24343902 12/18/2013    
  • Chemoprevention of lung squamous cell carcinoma by ginseng. (Pan J, Zhang Q, Li K, Liu Q, Wang Y, You M) Cancer Prev Res (Phila) 2013 Jun;6(6):530-9 PMID: 23550152 SCOPUS ID: 2-s2.0-84878883346 04/04/2013       10 Citations
  • Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR. (Kilari S, Remadevi I, Zhao B, Pan J, Miao R, Ramchandran R, North PE, You M, Rahimi N, Wilkinson GA) J Biol Chem 2013 Apr 12;288(15):10265-74 PMID: 23393131 PMCID: PMC3624410 SCOPUS ID: 2-s2.0-84876229992 02/09/2013       12 Citations
  • Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. (Liu P, Morrison C, Wang L, Xiong D, Vedell P, Cui P, Hua X, Ding F, Lu Y, James M, Ebben JD, Xu H, Adjei AA, Head K, Andrae JW, Tschannen MR, Jacob H, Pan J, Zhang Q, Van den Bergh F, Xiao H, Lo KC, Patel J, Richmond T, Watt MA, Albert T, Selzer R, Anderson M, Wang J, Wang Y, Starnes S, Yang P, You M) Carcinogenesis 2012 Jul;33(7):1270-6 PMID: 22510280 PMCID: PMC3499051 SCOPUS ID: 2-s2.0-84865168855 04/19/2012       130 Citations
  • Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-induced lung tumorigenesis through apoptosis. (Zhang Q, Pan J, Wang Y, Lubet R, You M) Mol Carcinog 2013 Sep;52(9):686-91 PMID: 22456940 SCOPUS ID: 2-s2.0-84881612712 03/30/2012       18 Citations
  • Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity. (Zhang Q, Pan J, North PE, Yang S, Lubet RA, Wang Y, You M) Cancer Prev Res (Phila) 2012 May;5(5):717-25 PMID: 22401980 SCOPUS ID: 2-s2.0-84866260153 03/10/2012       29 Citations
  • Chemoprevention of lung carcinogenesis by the combination of aerosolized budesonide and oral pioglitazone in A/J mice. (Fu H, Zhang J, Pan J, Zhang Q, Lu Y, Wen W, Lubet RA, Szabo E, Chen R, Wang Y, Chen DR, You M) Mol Carcinog 2011 Dec;50(12):913-21 PMID: 21374736 PMCID: PMC6015734 SCOPUS ID: 2-s2.0-80155129711 03/05/2011       28 Citations
  • Aerosolized bexarotene inhibits lung tumorigenesis without increasing plasma triglyceride and cholesterol levels in mice. (Zhang Q, Pan J, Zhang J, Liu P, Chen R, Chen DR, Lubet R, Wang Y, You M) Cancer Prev Res (Phila) 2011 Feb;4(2):270-6 PMID: 21163938 SCOPUS ID: 2-s2.0-79551709612 12/18/2010       18 Citations
  • 26S proteasome activity is down-regulated in lung cancer stem-like cells propagated in vitro. (Pan J, Zhang Q, Wang Y, You M) PLoS One 2010 Oct 11;5(10):e13298 PMID: 20949018 PMCID: PMC2952619 SCOPUS ID: 2-s2.0-78149423083 10/16/2010       48 Citations
  • Chemically oversulfated glycosaminoglycans are potent modulators of contact system activation and different cell signaling pathways. (Pan J, Qian Y, Zhou X, Lu H, Ramacciotti E, Zhang L) J Biol Chem 2010 Jul 23;285(30):22966-75 PMID: 20418371 PMCID: PMC2906290 SCOPUS ID: 2-s2.0-77953644228 04/27/2010       46 Citations
  • Oversulfated chondroitin sulfate is not the sole contaminant in heparin. (Pan J, Qian Y, Zhou X, Pazandak A, Frazier SB, Weiser P, Lu H, Zhang L) Nat Biotechnol 2010 Mar;28(3):203-7; author reply 207-11 PMID: 20212477 SCOPUS ID: 2-s2.0-77749298749 03/10/2010       56 Citations
  • Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate. (Snyder-Warwick AK, Perlyn CA, Pan J, Yu K, Zhang L, Ornitz DM) Proc Natl Acad Sci U S A 2010 Feb 09;107(6):2515-20 PMID: 20133659 PMCID: PMC2823872 SCOPUS ID: 2-s2.0-77249092531 02/06/2010       51 Citations
  • Effect of dietary Polyphenon E and EGCG on lung tumorigenesis in A/J Mice. (Zhang Q, Fu H, Pan J, He J, Ryota S, Hara Y, Wang Y, Lubet RA, You M) Pharm Res 2010 Jun;27(6):1066-71 PMID: 20112129 PMCID: PMC6007862 SCOPUS ID: 2-s2.0-77953232664 01/30/2010       26 Citations
  • Loss of dermatan-4-sulfotransferase 1 function results in adducted thumb-clubfoot syndrome. (Dündar M, Müller T, Zhang Q, Pan J, Steinmann B, Vodopiutz J, Gruber R, Sonoda T, Krabichler B, Utermann G, Baenziger JU, Zhang L, Janecke AR) Am J Hum Genet 2009 Dec;85(6):873-82 PMID: 20004762 PMCID: PMC2790573 SCOPUS ID: 2-s2.0-71149085178 12/17/2009       82 Citations
  • High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis. (Studelska DR, Mandik-Nayak L, Zhou X, Pan J, Weiser P, McDowell LM, Lu H, Liapis H, Allen PM, Shih FF, Zhang L) J Biol Chem 2009 Jan 23;284(4):2354-62 PMID: 18948258 PMCID: PMC2629098 SCOPUS ID: 2-s2.0-59049108108 10/25/2008       12 Citations
  • Last update: 01/28/2020
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