Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Josephine Allen PhD, MS

Josephine Allen PhD, MS profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Pediatrics Cardiology

Member of the Cardiovascular Research Center


I am willing to collaborate on research projects.
I am willing to be a peer mentor.
I am willing to mentor a junior faculty member.

Research Areas of Interest

  • Angiogenesis Inducing Agents
  • Aptamers, Nucleotide
  • Biocompatible Materials
  • Biopolymers
  • Bone Substitutes
  • Cardiovascular Deconditioning
  • Cardiovascular Diseases
  • Collagen
  • DNA
  • Hydrogels
  • Materials Science
  • Oligonucleotides
  • Peripheral Vascular Diseases
  • Polymers
  • Regenerative Medicine
  • Tissue Engineering
  • Vascular Diseases
  • Vascular Endothelial Growth Factor Receptor-2
  • Vascular Grafting
  • Vascular Remodeling

    • Leadership Positions

  • Director of Pediatric Cell and Tissue Engineering

    • Publications (53)

  • Injectable aptamer-functionalized nucleic acid-collagen hydrogels as a bioactive platform for angiogenic applications. (Pipis N, Traktuev DO, Liu Z, Allen JB) Biomater Adv 2026 Mar;180:214580 PMID: 41187655 PMCID: PMC12746834 SCOPUS ID: 2-s2.0-105022292318 11/05/2025    
  • Characterization of Sex-Based Differences in Integrin-Mediated Endothelial Cell Adhesion to Bioactive Hydrogels. (Nkansah A, Budhwani A, Grammer N, Ang N, Fairley A, Salazar SP, Chowdary AY, Anand A, Seidlits S, Allen J, Cosgriff-Hernandez E) ACS Biomater Sci Eng 2025 Nov 10;11(11):6515-6520 PMID: 41043183 SCOPUS ID: 2-s2.0-105021077657 10/03/2025       1 Citation
  • Toward Bioactive Hydrogels: A Tunable Approach via Nucleic Acid-Collagen Complexation. (Pipis N, Duraivel S, Subramaniam V, Stewart KA, Angelini TE, Allen JB) Regen Eng Transl Med 2024 Dec;10(4):564-576 PMID: 40718684 PMCID: PMC12291172 SCOPUS ID: 2-s2.0-85194574715 07/28/2025       5 Citations
  • Multifunctional DNA-Collagen Biomaterials: Developmental Advances and Biomedical Applications. (Pipis N, James BD, Allen JB) ACS Biomater Sci Eng 2025 Mar 10;11(3):1253-1268 PMID: 39869382 PMCID: PMC11897955 SCOPUS ID: 2-s2.0-85216345991 01/27/2025       9 Citations
  • Exploring the Fibrous Nature of Single-Stranded DNA-Collagen Complexes: Nanostructural Observations and Physicochemical Insights. (Pipis N, Stewart KA, Tabatabaei M, Williams LN, Allen JB) ACS Omega 2024 Jul 23;9(29):32052-32058 PMID: 39072094 PMCID: PMC11270544 SCOPUS ID: 2-s2.0-85199363515 07/29/2024       3 Citations
  • The Effects of Simulated and Real Microgravity on Vascular Smooth Muscle Cells. (Ludtka C, Allen JB) Gravit Space Res 2024 Jan;12(1):46-59 PMID: 38846256 PMCID: PMC11156189 06/07/2024    
  • Spaceflight effects on human vascular smooth muscle cell phenotype and function. (Scotti MM, Wilson BK, Bubenik JL, Yu F, Swanson MS, Allen JB) NPJ Microgravity 2024 Mar 28;10(1):41 PMID: 38548798 PMCID: PMC10979029 SCOPUS ID: 2-s2.0-85188785432 03/29/2024       10 Citations
  • Sex as a Biological Variable in Tissue Engineering and Regenerative Medicine. (Allen JB, Ludtka C, James BD) Annu Rev Biomed Eng 2023 Jun 08;25:311-331 PMID: 37104652 PMCID: PMC10312304 SCOPUS ID: 2-s2.0-85163400835 04/27/2023       13 Citations
  • Hemocompatibility of all-trans retinoic acid-loaded citrate polymer coatings for vascular stents. (Ursino H, Zhang B, Ludtka C, Webb A, Allen JB) Regen Eng Transl Med 2022 Dec;8(4):579-592 PMID: 36714809 PMCID: PMC9881644 SCOPUS ID: 2-s2.0-85129304066 01/31/2023       2 Citations
  • Ancestry of cells must be considered in bioengineering. (Moore E, Allen JB, Mulligan CJ, Wayne EC) Nat Rev Mater 2022 Jan;7(1):2-4 PMID: 37200939 PMCID: PMC10190130 SCOPUS ID: 2-s2.0-85118639042 01/01/2022       16 Citations
  • Macrophages in microgravity: the impact of space on immune cells (Ludtka C, Silberman J, Moore E, Allen JB) Npj Microgravity December 2021;7(1) SCOPUS ID: 2-s2.0-85106283670 12/01/2021       64 Citations
  • Ancestral Background Is Underreported in Regenerative Engineering. (Ryan H, Bister D, Holliday SA, Boehlein J, Lewis A, Silberman J, Allen JB, Moore E) Regen Eng Transl Med 2022;8(4):499-503 PMID: 34778512 PMCID: PMC8577639 SCOPUS ID: 2-s2.0-85118876059 11/16/2021       13 Citations
  • Engineering Vascular Grafts with Multiphase Structures. (James BD, Allen JB) Methods Mol Biol 2022;2375:115-124 PMID: 34591303 SCOPUS ID: 2-s2.0-85116911386 10/01/2021    
  • The Effects of Simulated Microgravity on Macrophage Phenotype. (Ludtka C, Moore E, Allen JB) Biomedicines 2021 Sep 12;9(9) PMID: 34572391 PMCID: PMC8472625 SCOPUS ID: 2-s2.0-85115247543 09/29/2021       20 Citations
  • Sex-Specific Response to Combinations of Shear Stress and Substrate Stiffness by Endothelial Cells In Vitro. (James BD, Allen JB) Adv Healthc Mater 2021 Sep;10(18):e2100735 PMID: 34142471 PMCID: PMC8458248 SCOPUS ID: 2-s2.0-85108004331 06/19/2021       21 Citations
  • Macrophages in microgravity: the impact of space on immune cells. (Ludtka C, Silberman J, Moore E, Allen JB) NPJ Microgravity 2021 Mar 31;7(1):13 PMID: 33790288 PMCID: PMC8012370 SCOPUS ID: 2-s2.0-85106283670 04/02/2021       63 Citations
  • Self-assembled VEGF-R2 targeting DNA aptamer-collagen fibers stimulate an angiogenic-like endothelial cell phenotype. (James BD, Allen JB) Mater Sci Eng C Mater Biol Appl 2021 Jan;120:111683 PMID: 33545845 SCOPUS ID: 2-s2.0-85095792020 02/07/2021       10 Citations
  • Fund Black scientists. (Stevens KR, Masters KS, Imoukhuede PI, Haynes KA, Setton LA, Cosgriff-Hernandez E, Lediju Bell MA, Rangamani P, Sakiyama-Elbert SE, Finley SD, Willits RK, Koppes AN, Chesler NC, Christman KL, Allen JB, Wong JY, El-Samad H, Desai TA, Eniola-Adefeso O) Cell 2021 Feb 04;184(3):561-565 PMID: 33503447 SCOPUS ID: 2-s2.0-85100271785 01/28/2021       118 Citations
  • Oligomer Length Defines the Self-Assembly of Single-Stranded DNA-Collagen Complex Fibers. (James BD, Saenz S, van Gent A, Allen JB) ACS Biomater Sci Eng 2020 Jan 13;6(1):213-218 PMID: 33463189 SCOPUS ID: 2-s2.0-85077228442 01/20/2021       9 Citations
  • Bone tissue engineering (Ursino HL, James BD, Ludtka CM, Allen JB) Tissue Engineering Using Ceramics and Polymers Third Edition 1 January 2021:587-644 SCOPUS ID: 2-s2.0-85129925135 01/01/2021       5 Citations
  • Anti-VEGF-R2 Aptamer and RGD Peptide Synergize in a Bifunctional Hydrogel for Enhanced Angiogenic Potential. (Roy T, James BD, Allen JB) Macromol Biosci 2021 Feb;21(2):e2000337 PMID: 33191671 PMCID: PMC7880904 SCOPUS ID: 2-s2.0-85097208307 11/17/2020       45 Citations
  • Let's Talk About Sex-Biological Sex Is Underreported in Biomaterial Studies. (James BD, Guerin P, Allen JB) Adv Healthc Mater 2021 Jan;10(1):e2001034 PMID: 33043626 PMCID: PMC7791002 SCOPUS ID: 2-s2.0-85092304195 10/13/2020       39 Citations
  • Mineralized DNA-collagen complex-based biomaterials for bone tissue engineering. (James BD, Guerin P, Iverson Z, Allen JB) Int J Biol Macromol 2020 Oct 15;161:1127-1139 PMID: 32561285 PMCID: PMC7494536 SCOPUS ID: 2-s2.0-85086789368 06/21/2020       25 Citations
  • MechanoBioTester: A Decoupled Multistimulus Cell Culture Device for Studying Complex Microenvironments in Vitro (James BD, James BD, Montoya N, Allen JB) ACS Biomaterials Science and Engineering 8 June 2020;6(6):3673-3689 SCOPUS ID: 2-s2.0-85085748839 06/08/2020       6 Citations
  • Palm readings: Manicaria saccifera palm fibers are biocompatible textiles with low immunogenicity. (James BD, Ruddick WN, Vasisth SE, Dulany K, Sulekar S, Porras A, Marañon A, Nino JC, Allen JB) Mater Sci Eng C Mater Biol Appl 2020 Mar;108:110484 PMID: 31924028 SCOPUS ID: 2-s2.0-85075756052 01/12/2020       19 Citations
  • In vitro and in vivo biocompatibility assessment of free radical scavenging nanocomposite scaffolds for bone tissue regeneration. (Dulany K, Hepburn K, Goins A, Allen JB) J Biomed Mater Res A 2020 Feb;108(2):301-315 PMID: 31606924 PMCID: PMC7700846 SCOPUS ID: 2-s2.0-85074611174 10/14/2019       42 Citations
  • Multi-layer approaches to scaffold-based small diameter vessel engineering: A review. (Goins A, Webb AR, Allen JB) Mater Sci Eng C Mater Biol Appl 2019 Apr;97:896-912 PMID: 30678980 SCOPUS ID: 2-s2.0-85059382254 01/27/2019       80 Citations
  • A decoupled multi-stimulus bioreactor for studying complex chemo-mechanical microenvironments in vitro (James BD, Montoya N, Ruddick W, Allen JB) Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium 2019;40:650 SCOPUS ID: 2-s2.0-85065406475 01/01/2019    
  • Fabrication of a Free Radical Scavenging Nanocomposite Scaffold for Bone Tissue Regeneration (Dulany K, Goins A, Kelley A, Allen JB) Regenerative Engineering and Translational Medicine 1 December 2018;4(4):257-267 SCOPUS ID: 2-s2.0-85061677583 12/01/2018       8 Citations
  • Vascular Endothelial Cell Behavior in Complex Mechanical Microenvironments (James BD, Allen JB) ACS Biomaterials Science and Engineering 12 November 2018;4(11):3818-3842 SCOPUS ID: 2-s2.0-85056872977 11/12/2018       47 Citations
  • Vascular Endothelial Cell Behavior in Complex Mechanical Microenvironments. (James BD, Allen JB) ACS Biomater Sci Eng 2018 Nov 12;4(11):3818-3842 PMID: 33429612 SCOPUS ID: 2-s2.0-85056872977 11/12/2018       47 Citations
  • Fabrication of a bilayer scaffold for small diameter vascular applications. (Goins A, Ramaswamy V, Lichlyter D, Webb A, Allen JB) J Biomed Mater Res A 2018 Nov;106(11):2850-2862 PMID: 30194900 SCOPUS ID: 2-s2.0-85052964955 09/09/2018       21 Citations
  • Mechanical and degradation property improvement in a biocompatible Mg-Ca-Sr alloy by thermomechanical processing. (Henderson HB, Ramaswamy V, Wilson-Heid AE, Kesler MS, Allen JB, Manuel MV) J Mech Behav Biomed Mater 2018 Apr;80:285-292 PMID: 29455038 SCOPUS ID: 2-s2.0-85042319439 02/20/2018       31 Citations
  • Development of poly (1,8 octanediol-co-citrate) and poly (acrylic acid) nanofibrous scaffolds for wound healing applications. (Goins A, Ramaswamy V, Dirr E, Dulany K, Irby S, Webb A, Allen J) Biomed Mater 2017 Oct 26;13(1):015002 PMID: 29072193 SCOPUS ID: 2-s2.0-85039784678 10/27/2017       39 Citations
  • The effect of Mg-Ca-Sr alloy degradation products on human mesenchymal stem cells. (Berglund IS, Dirr EW, Ramaswamy V, Allen JB, Allen KD, Manuel MV) J Biomed Mater Res B Appl Biomater 2018 Feb;106(2):697-704 PMID: 28323384 PMCID: PMC5811831 SCOPUS ID: 2-s2.0-85017377482 03/23/2017       24 Citations
  • Peri-implant tissue response and biodegradation performance of a Mg-1.0Ca-0.5Sr alloy in rat tibia. (Berglund IS, Jacobs BY, Allen KD, Kim SE, Pozzi A, Allen JB, Manuel MV) Mater Sci Eng C Mater Biol Appl 2016 May;62:79-85 PMID: 26952400 SCOPUS ID: 2-s2.0-84955482652 03/10/2016       37 Citations
  • The Effect of Simulated Microgravity on Differentiation of Porcine Blood-Derived Vascular Stem Cells. (Ramaswamy V, Dirr EW, Allen JB) Stem Cells Dev 2016 Feb 15;25(4):329-36 PMID: 26649474 SCOPUS ID: 2-s2.0-84958160275 12/10/2015       7 Citations
  • DNA Aptamer Assembly as a Vascular Endothelial Growth Factor Receptor Agonist. (Ramaswamy V, Monsalve A, Sautina L, Segal MS, Dobson J, Allen JB) Nucleic Acid Ther 2015 Oct;25(5):227-34 PMID: 26125598 PMCID: PMC4576944 SCOPUS ID: 2-s2.0-84941888936 07/01/2015       64 Citations
  • Advanced nanocomposites for bone regeneration. (Baler K , Ball JP , Cankova Z , Hoshi RA , Ameer GA , Allen JB ) Biomater Sci 2014 Oct 26;2(10):1355-1366 PMID: 32481912 SCOPUS ID: 2-s2.0-84906668387 10/26/2014       24 Citations
  • The role of surface oxidation on the degradation behavior of biodegradable Mg-RE (Gd, Y, Sc) alloys for resorbable implants. (Brar HS, Berglund IS, Allen JB, Manuel MV) Mater Sci Eng C Mater Biol Appl 2014 Jul 01;40:407-17 PMID: 24857509 SCOPUS ID: 2-s2.0-84899796907 05/27/2014       53 Citations
  • Biocompatibility evaluation of porous ceria foams for orthopedic tissue engineering. (Ball JP, Mound BA, Monsalve AG, Nino JC, Allen JB) J Biomed Mater Res A 2015 Jan;103(1):8-15 PMID: 24677427 SCOPUS ID: 2-s2.0-84912531363 03/29/2014       33 Citations
  • Advanced nanocomposites for bone regeneration (Baler K, Ball JP, Cankova Z, Hoshi RA, Ameer GA, Allen JB) Biomaterials Science October 2014;2(10):1355-1366 SCOPUS ID: 2-s2.0-84906668387 01/01/2014       24 Citations
  • Biocompatible evaluation of barium titanate foamed ceramic structures for orthopedic applications. (Ball JP, Mound BA, Nino JC, Allen JB) J Biomed Mater Res A 2014 Jul;102(7):2089-95 PMID: 23894063 SCOPUS ID: 2-s2.0-84901489450 07/31/2013       85 Citations
  • The blood and vascular cell compatibility of heparin-modified ePTFE vascular grafts. (Hoshi RA, Van Lith R, Jen MC, Allen JB, Lapidos KA, Ameer G) Biomaterials 2013 Jan;34(1):30-41 PMID: 23069711 PMCID: PMC4065598 SCOPUS ID: 2-s2.0-84868115647 10/17/2012       269 Citations
  • A study of a biodegradable Mg-3Sc-3Y alloy and the effect of self-passivation on the in vitro degradation. (Brar HS, Ball JP, Berglund IS, Allen JB, Manuel MV) Acta Biomater 2013 Feb;9(2):5331-40 PMID: 22902815 SCOPUS ID: 2-s2.0-84872063436 08/21/2012       69 Citations
  • Toward engineering a human neoendothelium with circulating progenitor cells. (Allen JB, Khan S, Lapidos KA, Ameer GA) Stem Cells 2010 Feb;28(2):318-28 PMID: 20013827 SCOPUS ID: 2-s2.0-77149164460 12/17/2009       51 Citations
  • Characterization of porcine circulating progenitor cells: toward a functional endothelium. (Allen J, Khan S, Serrano MC, Ameer G) Tissue Eng Part A 2008 Jan;14(1):183-94 PMID: 18333816 SCOPUS ID: 2-s2.0-38349107303 03/13/2008       44 Citations
  • Hemocompatibility evaluation of poly(diol citrate) in vitro for vascular tissue engineering. (Motlagh D, Allen J, Hoshi R, Yang J, Lui K, Ameer G) J Biomed Mater Res A 2007 Sep 15;82(4):907-16 PMID: 17335023 SCOPUS ID: 2-s2.0-34548180543 03/06/2007       130 Citations
  • Isolation and differentiation of porcine progenitor cells into endothelial-like cells for vascular tissue engineering (Allen JB, Khan S, Motlagh D, Serrano MC, Shekaran A, Ameer GA) Aiche Annual Meeting Conference Proceedings 2006 SCOPUS ID: 2-s2.0-57049185151 12/01/2006    
  • Spectroscopic translation of cell-material interactions. (Allen J, Liu Y, Kim YL, Turzhitsky VM, Backman V, Ameer GA) Biomaterials 2007 Jan;28(2):162-74 PMID: 16884769 SCOPUS ID: 2-s2.0-33749605689 08/04/2006       9 Citations
  • Modulating expanded polytetrafluoroethylene vascular graft host response via citric acid-based biodegradable elastomers (Yang J, Motlagh D, Allen JB, Webb AR, Kibbe MR, Aalami O, Kapadia M, Carroll TJ, Ameer GA) Advanced Materials 19 June 2006;18(12):1493-1498 SCOPUS ID: 2-s2.0-33745535280 06/19/2006       95 Citations
  • Assessing cell-material interactions on a novel biodegradable elastomer (Allen J, Liu Y, Turzhitsky V, Backman V, Ameer G) Aiche Annual Meeting Conference Proceedings 2004:1265-1267 SCOPUS ID: 2-s2.0-22544450834 12/01/2004    
  • Light scattering "fingerprinting" for characterization of smooth muscle cell proliferation (Liu Y, Allen J, Kim YL, Turzhitsky V, Ameer G, Backman V) Proceedings of SPIE the International Society for Optical Engineering 2004;5319:32-40 SCOPUS ID: 2-s2.0-5644292031 10/27/2004    
    • Last update: 03/16/2026