Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Lavanya Choppavarapu

Research Scientist I

Institution: Medical College of Wisconsin
Department: Data Science Institute

Publications (14)

  • 3D Chromatin Alteration by Disrupting β-Catenin/CBP Interaction Is Enriched with Insulin Signaling in Pancreatic Cancer. (Zhou Y, He Z, Li T, Choppavarapu L, Hu X, Cao R, Leone GW, Kahn M, Jin VX) Cancers (Basel) 2024 Jun 12;16(12) PMID: 38927910 PMCID: PMC11201718 SCOPUS ID: 2-s2.0-85197122887 06/27/2024       2 Citations
  • Hi-C profiling in tissues reveals 3D chromatin-regulated breast tumor heterogeneity and tumor-specific looping-mediated biological pathways. (Choppavarapu L, Fang K, Liu T, Jin VX) bioRxiv 2024 Mar 13 PMID: 38559097 PMCID: PMC10979939 04/01/2024    
  • Reprogramming of 3D chromatin domains by antagonizing the β-catenin/CBP interaction attenuates insulin signaling in pancreatic cancer. (Zhou Y, Li T, He Z, Choppavarapu L, Hu X, Cao R, Leone GW, Kahn M, Jin VX) bioRxiv 2023 Nov 14 PMID: 38013997 PMCID: PMC10680786 11/28/2023    
  • Integration of scHi-C and scRNA-seq data defines distinct 3D-regulated and biological-context dependent cell subpopulations. (Zhou Y, Li T, Choppavarapu L, Jin VX) bioRxiv 2023 Oct 02 PMID: 37873257 PMCID: PMC10592853 10/24/2023    
  • Hi-C profiling of cancer spheroids identifies 3D-growth-specific chromatin interactions in breast cancer endocrine resistance. (Li J, Fang K, Choppavarapu L, Yang K, Yang Y, Wang J, Cao R, Jatoi I, Jin VX) Clin Epigenetics 2021 Sep 17;13(1):175 PMID: 34535185 PMCID: PMC8447690 SCOPUS ID: 2-s2.0-85115159581 09/19/2021       17 Citations
  • The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells. (Yang Y, Choppavarapu L, Fang K, Naeini AS, Nosirov B, Li J, Yang K, He Z, Zhou Y, Schiff R, Li R, Hu Y, Wang J, Jin VX) Biochim Biophys Acta Gene Regul Mech 2020 Nov;1863(11):194631 PMID: 32956836 PMCID: PMC7686120 SCOPUS ID: 2-s2.0-85091761490 09/22/2020       13 Citations
  • Circulating MicroRNAs as Potential Biomarkers in Glioma: A Mini-Review. (Choppavarapu L, Kandi SM) Endocr Metab Immune Disord Drug Targets 2021;21(2):195-202 PMID: 32744979 SCOPUS ID: 2-s2.0-85101030452 08/04/2020       4 Citations
  • Down regulation of human telomerase reverse transcriptase (hTERT) expression by BIBR1532 in human glioblastoma LN18 cells (C Lavanya, Manjunatha M Venkataswamy, MK Sibin, MM Srinivas Bharath, GK Chetan) Cytotechnology 08/15/2018    
  • RNA interference mediated downregulation of human telomerase reverse transcriptase (hTERT) in LN18 cells. (Lavanya C, Sibin MK, Srinivas Bharath MM, Manoj MJ, Venkataswamy MM, Bhat DI, Narasinga Rao KV, Chetan GK) Cytotechnology 2016 Dec;68(6):2311-2321 PMID: 27757712 PMCID: PMC5101301 SCOPUS ID: 2-s2.0-84991577779 10/21/2016       9 Citations
  • Role of Concurrent Methylation Pattern of MGMT, TP53 and CDKN2A Genes in the Prognosis of High Grade Glioma (Jeru-Manoj Manuel1 , Debarati Ghosh1 , Narasinga Rao KVL 2 , Sibin MK1 , Venkatesh HN 1 , Lavanya Ch1 , Arati S1 , Dhananjaya I Bhat2 , Srinivas Bharath MM3 , Chetan GK1* ) Carcinogenesis & Mutagenesis 01/25/2016    
  • Overexpression and lack of copy number variation in the BMI-1 gene in human glioma. (Madathan Kandy S, Ishwara Bhat D, Choppavarapu L, Suvatha A, Ghati Kasturirangan C) Oncol Lett 2015 Nov;10(5):3318-3322 PMID: 26722333 PMCID: PMC4665956 SCOPUS ID: 2-s2.0-84942475370 01/02/2016       4 Citations
  • CD133 and BMI1 expressions and its prognostic role in primary glioblastoma. (Sibin MK, Lavanya CH, Bhat DI, Rao N, Geethashree N, Vibhuti W, Chetan GK) J Genet 2015 Dec;94(4):689-96 PMID: 26690524 SCOPUS ID: 2-s2.0-84953637077 12/23/2015       6 Citations
  • CDKN2A (p16) mRNA decreased expression is a marker of poor prognosis in malignant high-grade glioma. (Sibin MK, Bhat DI, Narasingarao KV, Lavanya Ch, Chetan GK) Tumour Biol 2015 Sep;36(10):7607-14 PMID: 25921285 SCOPUS ID: 2-s2.0-84944278122 04/30/2015       17 Citations
  • CDKN2A exon-wise deletion status and novel somatic mutations in Indian glioma patients. (Sibin MK, Bhat DI, Lavanya Ch, Manoj MJ, Aakershita S, Chetan GK) Tumour Biol 2014 Feb;35(2):1467-72 PMID: 24065197 SCOPUS ID: 2-s2.0-84898857554 09/26/2013       8 Citations
    • Last update: 08/27/2024