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Manoj Paul PhD
Postdoctoral Researcher 1
Institution:
Medical College of Wisconsin
Department:
Surgery
Division:
Vascular Surgery
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Publications (30)
Gelsolin controls the release of phosphatidylserine (PS)-positive microvesicles (MVs) from platelets.
(Paul M, Hong F, Falet H, Kim H)
Cell Signal
2024 Dec;124:111433 PMID: 39321905 SCOPUS ID: 2-s2.0-85204979070 09/26/2024
Gelsolin regulates receptor-mediated and fluid-phase endocytosis in platelets.
(Paul M, Hong F, Falet H, Kim H)
J Thromb Haemost
2024 Sep;22(9):2601-2607 PMID: 38777258 SCOPUS ID: 2-s2.0-85200222449 05/23/2024
Oxidative Stress-Induced Platelet Apoptosis/Activation: Alleviation by Purified Curcumin via ASK1-JNK/p-38 Pathway.
(Manikanta K, Paul M, Sandesha VD, Mahalingam SS, Ramesh TN, Harishkumar K, Koundinya SS, Naveen S, Kemparaju K, Girish KS)
Biochemistry (Mosc)
2024 Mar;89(3):417-430 PMID: 38648762 SCOPUS ID: 2-s2.0-85191378390 04/23/2024
2 Citations
Genetically engineered transfusable platelets using mRNA lipid nanoparticles.
(Leung J, Strong C, Badior KE, Robertson M, Wu X, Meledeo MA, Kang E, Paul M, Sato Y, Harashima H, Cap AP, Devine DV, Jan E, Cullis PR, Kastrup CJ)
Sci Adv
2023 Dec;9(48):eadi0508 PMID: 38039367 PMCID: PMC10691771 SCOPUS ID: 2-s2.0-85178329611 12/01/2023
7 Citations
A novel association between platelet filamin A and soluble N-ethylmaleimide sensitive factor attachment proteins regulates granule secretion.
(Golla K, Paul M, Lengyell TC, Simpson EM, Falet H, Kim H)
Res Pract Thromb Haemost
2023 May;7(4):100019 PMID: 37538498 PMCID: PMC10394388 SCOPUS ID: 2-s2.0-85159331097 08/04/2023
3 Citations
Gelsolin Modulates Platelet Dense Granule Secretion and Hemostasis via the Actin Cytoskeleton.
(Paul M, Golla K, Kim H)
Thromb Haemost
2023 Feb;123(2):219-230 PMID: 36522181 SCOPUS ID: 2-s2.0-85144855694 12/16/2022
7 Citations
Apoptosis in platelets is independent of the actin cytoskeleton.
(De Silva E, Paul M, Kim H)
PLoS One
2022;17(11):e0276584 PMID: 36378629 PMCID: PMC9665360 SCOPUS ID: 2-s2.0-85142207081 11/16/2022
1 Citation
Bisphenol AF elevates procoagulant platelets by inducing necroptosis via RIPK1-inflammasome axis.
(Vishalakshi GJ, Hemshekhar M, Sandesha VD, Prashanth KS, Jagadish S, Paul M, Kemparaju K, Girish KS)
Toxicology
2021 Apr 30;454:152742 PMID: 33662508 SCOPUS ID: 2-s2.0-85102099788 03/05/2021
6 Citations
Structure and morphological studies of curcuminoids and curcuminoid mixture
(Ramesh TN, Paul M, Manikanta K, Girish KS)
Journal of Crystal Growth
1 October 2020;547 SCOPUS ID: 2-s2.0-85088914109 10/01/2020
8 Citations
Protective Effect of Tamarind Seed Coat Ethanol Extract on Eryptosis Induced by Oxidative Stress.
(Kengaiah J, Nandish SKM, Ramachandraiah C, Chandramma, Shivaiah A, Vishalakshi GJ, Paul M, Santhosh MS, Shankar RL, Sannaningaiah D)
Biochemistry (Mosc)
2020 Jan;85(1):119-129 PMID: 32079523 SCOPUS ID: 2-s2.0-85079144628 02/23/2020
7 Citations
Bisdemethoxycurcumin promotes apoptosis in human platelets via activation of ERK signaling pathway.
(Paul M, Manikanta K, Hemshekhar M, Sundaram MS, Naveen S, Ramesh TN, Kemparaju K, Girish KS)
Toxicol In Vitro
2020 Mar;63:104743 PMID: 31809793 SCOPUS ID: 2-s2.0-85076135596 12/07/2019
11 Citations
Porphyromonas gingivalis lipopolysaccharide activates platelet Cdc42 and promotes platelet spreading and thrombosis.
(Senini V, Amara U, Paul M, Kim H)
J Periodontol
2019 Nov;90(11):1336-1345 PMID: 31106406 SCOPUS ID: 2-s2.0-85074745809 05/21/2019
23 Citations
A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.
(Rashmi KC, Harsha Raj M, Paul M, Girish KS, Salimath BP, Aparna HS)
Chem Biol Interact
2019 Feb 01;299:120-130 PMID: 30543781 SCOPUS ID: 2-s2.0-85058397714 12/14/2018
35 Citations
Berberine mitigates high glucose-potentiated platelet aggregation and apoptosis by modulating aldose reductase and NADPH oxidase activity.
(Paul M, Hemshekhar M, Kemparaju K, Girish KS)
Free Radic Biol Med
2019 Jan;130:196-205 PMID: 30391673 SCOPUS ID: 2-s2.0-85056228090 11/06/2018
53 Citations
Aggregation is impaired in starved platelets due to enhanced autophagy and cellular energy depletion.
(Paul M, Hemshekhar M, Kemparaju K, Girish KS)
Platelets
2019;30(4):487-497 PMID: 29799304 SCOPUS ID: 2-s2.0-85047426791 05/26/2018
18 Citations
Inhibition of constitutive NF-κB activity induces platelet apoptosis via ER stress.
(Paul M, Kemparaju K, Girish KS)
Biochem Biophys Res Commun
2017 Dec 02;493(4):1471-1477 PMID: 28986259 SCOPUS ID: 2-s2.0-85030676034 10/08/2017
19 Citations
Bone Degeneration, Inflammation and Secondary Complications of Arthritis: Potential Targets and their Natural Inhibitors.
(Hemshekhar M, Thushara RM, Kumar SKN, Paul M, Sundaram MS, Kemparaju K, Girish KS)
Mini Rev Med Chem
2018;18(3):244-275 PMID: 28302039 SCOPUS ID: 2-s2.0-85041641048 03/18/2017
7 Citations
Novel sila-amide derivatives of N-acetylcysteine protects platelets from oxidative stress-induced apoptosis.
(Paul M, Thushara RM, Jagadish S, Zakai UI, West R, Kemparaju K, Girish KS)
J Thromb Thrombolysis
2017 Feb;43(2):209-216 PMID: 27804000 SCOPUS ID: 2-s2.0-84994160237 11/03/2016
13 Citations
NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction.
(Katkar GD, Sundaram MS, NaveenKumar SK, Swethakumar B, Sharma RD, Paul M, Vishalakshi GJ, Devaraja S, Girish KS, Kemparaju K)
Nat Commun
2016 Apr 19;7:11361 PMID: 27093631 PMCID: PMC4838891 SCOPUS ID: 2-s2.0-84973359653 04/20/2016
69 Citations
Platelet protective efficacy of 3,4,5 trisubstituted isoxazole analogue by inhibiting ROS-mediated apoptosis and platelet aggregation.
(Jagadish S, Rajeev N, NaveenKumar SK, Sharath Kumar KS, Paul M, Hegde M, Basappa, Sadashiva MP, Girish KS, Rangappa KS)
Mol Cell Biochem
2016 Mar;414(1-2):137-51 PMID: 26899710 SCOPUS ID: 2-s2.0-84959091244 02/24/2016
29 Citations
Animal models used in studying inflammatory bowel diseases
(Swethakumar B, Paul M, Girish KS, Kemparaju K)
Disorders of Gastrointestinal Systems and Clinical Manifestations
1 January 2016:67-88 SCOPUS ID: 2-s2.0-85060811221 01/01/2016
Unconjugated Bilirubin exerts Pro-Apoptotic Effect on Platelets via p38-MAPK activation.
(NaveenKumar SK, Thushara RM, Sundaram MS, Hemshekhar M, Paul M, Thirunavukkarasu C, Basappa, Nagaraju G, Raghavan SC, Girish KS, Kemparaju K, Rangappa KS)
Sci Rep
2015 Oct 13;5:15045 PMID: 26459859 PMCID: PMC4602209 SCOPUS ID: 2-s2.0-84944326258 10/16/2015
56 Citations
Oxidative stress-induced methemoglobinemia is the silent killer during snakebite: a novel and strategic neutralization by melatonin.
(Sharma RD, Katkar GD, Sundaram MS, Paul M, NaveenKumar SK, Swethakumar B, Hemshekhar M, Girish KS, Kemparaju K)
J Pineal Res
2015 Sep;59(2):240-54 PMID: 26103459 SCOPUS ID: 2-s2.0-84938320613 06/24/2015
30 Citations
Methotrexate Promotes Platelet Apoptosis via JNK-Mediated Mitochondrial Damage: Alleviation by N-Acetylcysteine and N-Acetylcysteine Amide.
(Paul M, Hemshekhar M, Thushara RM, Sundaram MS, NaveenKumar SK, Naveen S, Devaraja S, Somyajit K, West R, Basappa, Nayaka SC, Zakai UI, Nagaraju G, Rangappa KS, Kemparaju K, Girish KS)
PLoS One
2015;10(6):e0127558 PMID: 26083398 PMCID: PMC4471342 SCOPUS ID: 2-s2.0-84939209556 06/18/2015
57 Citations
Tamarind Seed (Tamarindus indica) Extract Ameliorates Adjuvant-Induced Arthritis via Regulating the Mediators of Cartilage/Bone Degeneration, Inflammation and Oxidative Stress.
(Sundaram MS, Hemshekhar M, Santhosh MS, Paul M, Sunitha K, Thushara RM, NaveenKumar SK, Naveen S, Devaraja S, Rangappa KS, Kemparaju K, Girish KS)
Sci Rep
2015 Jun 10;5:11117 PMID: 26059174 PMCID: PMC4461917 SCOPUS ID: 2-s2.0-84931274953 06/11/2015
47 Citations
Correction: A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis
(Rakesh KS, Jagadish S, Vinayaka AC, Hemshekhar M, Paul M)
PLoS ONE
24 November 2014;9(11) SCOPUS ID: 2-s2.0-84912570953 11/24/2014
2 Citations
A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis.
(Rakesh KS, Jagadish S, Vinayaka AC, Hemshekhar M, Paul M, Thushara RM, Sundaram MS, Swaroop TR, Mohan CD, Basappa, Sadashiva MP, Kemparaju K, Girish KS, Rangappa KS)
PLoS One
2014;9(9):e107182 PMID: 25238069 PMCID: PMC4169656 SCOPUS ID: 2-s2.0-84907212853 09/23/2014
36 Citations
Crocin prevents sesamol-induced oxidative stress and apoptosis in human platelets.
(Thushara RM, Hemshekhar M, Paul M, Shanmuga Sundaram M, Shankar RL, Kemparaju K, Girish KS)
J Thromb Thrombolysis
2014 Oct;38(3):321-30 PMID: 24705676 SCOPUS ID: 2-s2.0-84906939133 04/08/2014
17 Citations
Tamarind seed extract mitigates the liver oxidative stress in arthritic rats.
(Sundaram MS, Hemshekhar M, Thushara RM, Santhosh MS, Kumar SK, Paul M, Devaraja S, Kemparaju K, Rangappa KS, Girish KS)
Food Funct
2014 Mar;5(3):587-97 PMID: 24500568 SCOPUS ID: 2-s2.0-84896810680 02/07/2014
24 Citations
Melatonin elevates apoptosis in human platelets via ROS mediated mitochondrial damage.
(Girish KS, Paul M, Thushara RM, Hemshekhar M, Shanmuga Sundaram M, Rangappa KS, Kemparaju K)
Biochem Biophys Res Commun
2013 Aug 16;438(1):198-204 PMID: 23880341 SCOPUS ID: 2-s2.0-84881552543 07/25/2013
68 Citations
Last update: 02/03/2025