Medical College of Wisconsin
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Ming You MD, PhD

Ming You MD, PhD profile photo picture

Associate Provost, Professor

Institution: Medical College of Wisconsin
Department: Pharmacology and Toxicology
Program: Pharmacology

Director of the Center for Disease Prevention Research (CDPR)
Member of the Cancer Center
Member of the Cardiovascular Center


Research Experience

  • Carcinoma, Non-Small-Cell Lung
  • Carcinoma, Small Cell
  • Chemoprevention
  • DNA Fingerprinting
  • Genes, Neoplasm
  • Molecular Biology
  • Tumor Suppressor Protein p53
  • Publications (237)

  • miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer. (Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2019 12 24;29(13):4389-4406.e10 PMID: 31875548 PMCID: PMC7380555 SCOPUS ID: 2-s2.0-85076674271 12/26/2019       7 Citations
  • Increased formation of reactive oxygen species during tumor growth: Ex vivo low-temperature EPR and in vivo bioluminescence analyses. (Cheng G, Pan J, Podsiadly R, Zielonka J, Garces AM, Dias Duarte Machado LG, Bennett B, McAllister D, Dwinell MB, You M, Kalyanaraman B) Free Radic Biol Med 2020 02 01;147:167-174 PMID: 31874251 PMCID: PMC6948008 SCOPUS ID: 2-s2.0-85076857582 12/25/2019       2 Citations
  • Whole Exome Sequencing of Highly Aggregated Lung Cancer Families Reveals Linked Loci for Increased Cancer Risk on Chromosomes 12q, 7p, and 4q. (Musolf AM, Moiz BA, Sun H, Pikielny CW, Bossé Y, Mandal D, de Andrade M, Gaba C, Yang P, Li Y, You M, Govindan R, Wilson RK, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE) Cancer Epidemiol Biomarkers Prev 2020 02;29(2):434-442 PMID: 31826912 PMCID: PMC7007362 SCOPUS ID: 2-s2.0-85079076161 12/13/2019    
  • Potentiation of Kras peptide cancer vaccine by avasimibe, a cholesterol modulator. (Pan J, Zhang Q, Palen K, Wang L, Qiao L, Johnson B, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M) EBioMedicine 2019 Nov;49:72-81 PMID: 31680003 PMCID: PMC6945201 SCOPUS ID: 2-s2.0-85074132937 11/05/2019       2 Citations
  • Tumor intrinsic immunity related proteins may be novel tumor suppressors in some types of cancer. (Xiong D, Wang Y, You M) Sci Rep 2019 07 29;9(1):10918 PMID: 31358815 PMCID: PMC6662687 SCOPUS ID: 2-s2.0-85069918844 07/31/2019       4 Citations
  • Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis. (Cheng G, Zhang Q, Pan J, Lee Y, Ouari O, Hardy M, Zielonka M, Myers CR, Zielonka J, Weh K, Chang AC, Chen G, Kresty L, Kalyanaraman B, You M) Nat Commun 2019 05 17;10(1):2205 PMID: 31101821 PMCID: PMC6525201 SCOPUS ID: 2-s2.0-85065824371 05/19/2019       13 Citations
  • Exosomal miRNAs as Novel Pharmacodynamic Biomarkers for Cancer Chemopreventive Agent Early Stage Treatments in Chemically Induced Mouse Model of Lung Squamous Cell Carcinoma. (Zhou Y, Zhang Q, Du M, Xiong D, Wang Y, Mohammed A, Lubet RA, Wang L, You M) Cancers (Basel) 2019 Apr 04;11(4) PMID: 30987362 PMCID: PMC6520832 04/17/2019    
  • Optimized Bexarotene Aerosol Formulation Inhibits Major Subtypes of Lung Cancer in Mice. (Zhang Q, Lee SB, Chen X, Stevenson ME, Pan J, Xiong D, Zhou Y, Miller MS, Lubet RA, Wang Y, Mirza SP, You M) Nano Lett 2019 04 10;19(4):2231-2242 PMID: 30873838 SCOPUS ID: 2-s2.0-85063522412 03/16/2019       1 Citation
  • Integrative system genetic analysis reveals mRNA-lncRNA network associated with mouse spontaneous lung cancer susceptibility. (Zhou Y, You M) Oncotarget 2019 Jan 08;10(3):339-351 PMID: 30719228 PMCID: PMC6349452 02/06/2019    
  • Integrative system genetic analysis reveals mRNA-lncRNA network associated with mouse spontaneous lung cancer susceptibility (Zhou Y, You M) Oncotarget 1 January 2019;10(3):339-351 SCOPUS ID: 2-s2.0-85059596065 01/01/2019    
  • Potentiation of Kras peptide cancer vaccine by avasimibe, a cholesterol modulator (Pan J, Zhang Q, Palen K, Wang L, Qiao L, Johnson B, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M) EBioMedicine 2019 SCOPUS ID: 2-s2.0-85074132937 01/01/2019    
  • Immunogenomic Landscape Contributes to Hyperprogressive Disease after Anti-PD-1 Immunotherapy for Cancer. (Xiong D, Wang Y, Singavi AK, Mackinnon AC, George B, You M) iScience 2018 Nov 30;9:258-277 PMID: 30439581 PMCID: PMC6234258 11/16/2018    
  • Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity. (Pan J, Lee Y, Cheng G, Zielonka J, Zhang Q, Bajzikova M, Xiong D, Tsaih SW, Hardy M, Flister M, Olsen CM, Wang Y, Vang O, Neuzil J, Myers CR, Kalyanaraman B, You M) iScience 2018 May 25;3:192-207 PMID: 30428319 PMCID: PMC6137433 11/15/2018    
  • Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. (Liu Y, Lusk CM, Cho MH, Silverman EK, Qiao D, Zhang R, Scheurer ME, Kheradmand F, Wheeler DA, Tsavachidis S, Armstrong G, Zhu D, Wistuba II, Chow CB, Behrens C, Pikielny CW, Neslund-Dudas C, Pinney SM, Anderson M, Kupert E, Bailey-Wilson J, Gaba C, Mandal D, You M, de Andrade M, Yang P, Field JK, Liloglou T, Davies M, Lissowska J, Swiatkowska B, Zaridze D, Mukeriya A, Janout V, Holcatova I, Mates D, Milosavljevic S, Scelo G, Brennan P, McKay J, Liu G, Hung RJ, Christiani DC, Schwartz AG, Amos CI, Spitz MR) J Thorac Oncol 2018 10;13(10):1483-1495 PMID: 29981437 PMCID: PMC6366341 SCOPUS ID: 2-s2.0-85051695595 07/08/2018       5 Citations
  • Genome-wide association study of familial lung cancer. (Byun J, Schwartz AG, Lusk C, Wenzlaff AS, de Andrade M, Mandal D, Gaba C, Yang P, You M, Kupert EY, Anderson MW, Han Y, Li Y, Qian D, Stilp A, Laurie C, Nelson S, Zheng W, Hung RJ, Gaborieau V, Mckay J, Brennan P, Caporaso NE, Landi MT, Wu X, McLaughlin JR, Brhane Y, Bossé Y, Pinney SM, Bailey-Wilson JE, Amos CI) Carcinogenesis 2018 09 21;39(9):1135-1140 PMID: 29924316 PMCID: PMC6148967 SCOPUS ID: 2-s2.0-85054876000 06/21/2018       8 Citations
  • Airway brushing as a new experimental methodology to detect airway gene expression signatures in mouse lung squamous cell carcinoma. (Pan J, Xiong D, Zhang Q, Szabo E, Miller MS, Lubet RA, Wang Y, You M) Sci Rep 2018 06 11;8(1):8895 PMID: 29891994 PMCID: PMC5995924 SCOPUS ID: 2-s2.0-85048432720 06/13/2018       1 Citation
  • Novel mutational landscapes and expression signatures of lung squamous cell carcinoma. (Xiong D, Pan J, Yin Y, Jiang H, Szabo E, Lubet RA, Wang Y, You M) Oncotarget 2018 Jan 26;9(7):7424-7441 PMID: 29484121 PMCID: PMC5800913 02/28/2018    
  • Immunoprevention of KRAS-driven lung adenocarcinoma by a multipeptide vaccine. (Pan J, Zhang Q, Sei S, Shoemaker RH, Lubet RA, Wang Y, You M) Oncotarget 2017 Oct 10;8(47):82689-82699 PMID: 29137294 PMCID: PMC5669920 11/16/2017    
  • Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer. (Zhang Q, Li R, Chen X, Lee SB, Pan J, Xiong D, Hu J, Miller MS, Szabo E, Lubet RA, Wang Y, You M) Oncotarget 2017 Sep 22;8(42):72447-72456 PMID: 29069801 PMCID: PMC5641144 10/27/2017    
  • Parametric Linkage Analysis Identifies Five Novel Genome-Wide Significant Loci for Familial Lung Cancer. (Musolf AM, Simpson CL, de Andrade M, Mandal D, Gaba C, Yang P, Li Y, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE) Hum Hered 2016;82(1-2):64-74 PMID: 28817824 08/18/2017    
  • Corrupting the DNA damage response: a critical role for Rad52 in tumor cell survival. (Lieberman R, You M) Aging (Albany NY) 2017 07 15;9(7):1647-1659 PMID: 28722656 PMCID: PMC5559167 SCOPUS ID: 2-s2.0-85026647869 07/20/2017       9 Citations
  • Pioglitazone-mediated reversal of elevated glucose metabolism in the airway epithelium of mouse lung adenocarcinomas. (Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, Wang Y, You M) JCI Insight 2017 Jul 06;2(13) PMID: 28679956 PMCID: PMC5499364 SCOPUS ID: 2-s2.0-85062389798 07/07/2017    
  • Rad52 deficiency decreases development of lung squamous cell carcinomas by enhancing immuno-surveillance. (Lieberman R, Pan J, Zhang Q, You M) Oncotarget 2017 May 23;8(21):34032-34044 PMID: 28415565 PMCID: PMC5470949 04/19/2017    
  • Familial Lung Cancer: A Brief History from the Earliest Work to the Most Recent Studies. (Musolf AM, Simpson CL, de Andrade M, Mandal D, Gaba C, Yang P, Li Y, You M, Kupert EY, Anderson MW, Schwartz AG, Pinney SM, Amos CI, Bailey-Wilson JE) Genes (Basel) 2017 Jan 17;8(1) PMID: 28106732 PMCID: PMC5295030 01/21/2017    
  • Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. (Xiong D, Pan J, Zhang Q, Szabo E, Miller MS, Lubet RA, You M, Wang Y) Oncotarget 2017 Mar 21;8(12):18885-18900 PMID: 27935865 PMCID: PMC5386655 12/10/2016    
  • Honokiol Decreases Lung Cancer Metastasis through Inhibition of the STAT3 Signaling Pathway. (Pan J, Lee Y, Zhang Q, Xiong D, Wan TC, Wang Y, You M) Cancer Prev Res (Phila) 2017 Feb;10(2):133-141 PMID: 27849557 PMCID: PMC6005650 SCOPUS ID: 2-s2.0-85012027149 11/17/2016       18 Citations
  • miR-375 induces docetaxel resistance in prostate cancer by targeting SEC23A and YAP1. (Wang Y, Lieberman R, Pan J, Zhang Q, Du M, Zhang P, Nevalainen M, Kohli M, Shenoy NK, Meng H, You M, Wang L) Mol Cancer 2016 11 10;15(1):70 PMID: 27832783 PMCID: PMC5105253 SCOPUS ID: 2-s2.0-84995489496 11/12/2016       57 Citations
  • Brain metastasis in lung cancer: Building a molecular and systems-level understanding to improve outcomes. (Ebben JD, You M) Int J Biochem Cell Biol 2016 09;78:288-296 PMID: 27474492 PMCID: PMC6020150 SCOPUS ID: 2-s2.0-84979929584 07/31/2016       11 Citations
  • Honokiol targets mitochondria to halt cancer progression and metastasis. (Pan J, Lee Y, Wang Y, You M) Mol Nutr Food Res 2016 06;60(6):1383-95 PMID: 27276215 SCOPUS ID: 2-s2.0-84973462458 06/09/2016       28 Citations
  • Chemoprevention of lung cancer by ginseng (You MS, Rouggly LC, Hu M, Yang Z, You M, Wang Y) Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention 19 April 2016:495-527 SCOPUS ID: 2-s2.0-85053021455 04/19/2016    
  • Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. (Liu Y, Kheradmand F, Davis CF, Scheurer ME, Wheeler D, Tsavachidis S, Armstrong G, Simpson C, Mandal D, Kupert E, Anderson M, You M, Xiong D, Pikielny C, Schwartz AG, Bailey-Wilson J, Gaba C, De Andrade M, Yang P, Pinney SM, Genetic Epidemiology of Lung Cancer Consortium, Amos CI, Spitz MR) J Thorac Oncol 2016 Jan;11(1):52-61 PMID: 26762739 PMCID: PMC4714038 SCOPUS ID: 2-s2.0-84959355448 01/15/2016       12 Citations
  • Patterns and functional implications of rare germline variants across 12 cancer types. (Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, Schmidt HK, Fulton RS, McMichael JF, Batra P, Kandoth C, Bharadwaj M, Koboldt DC, Miller CA, Kanchi KL, Eldred JM, Larson DE, Welch JS, You M, Ozenberger BA, Govindan R, Walter MJ, Ellis MJ, Mardis ER, Graubert TA, Dipersio JF, Ley TJ, Wilson RK, Goodfellow PJ, Raphael BJ, Chen F, Johnson KJ, Parvin JD, Ding L) Nat Commun 2015 Dec 22;6:10086 PMID: 26689913 PMCID: PMC4703835 SCOPUS ID: 2-s2.0-84951293785 12/23/2015       114 Citations
  • Anti-tumor Properties of Prunella vulgaris (Huang M, Wang Y, Xu L, You M) Current Pharmacology Reports 1 December 2015;1(6):401-419 SCOPUS ID: 2-s2.0-84978816958 12/01/2015    
  • Lung Cancer Prevention and Therapy Using the JinFuKang Herbal Mixture (Jiao L, Wang Y, Xu L, You M) Current Pharmacology Reports 1 October 2015;1(5):346-353 SCOPUS ID: 2-s2.0-84978540316 10/01/2015    
  • Epidermal growth factor receptor derived peptide vaccination to prevent lung adenocarcinoma formation: An in vivo study in a murine model of EGFR mutant lung cancer. (Ebben JD, Lubet RA, Gad E, Disis ML, You M) Mol Carcinog 2016 Nov;55(11):1517-1525 PMID: 26346412 PMCID: PMC6019616 SCOPUS ID: 2-s2.0-84941114100 09/09/2015       10 Citations
  • PARK2 gene and familial lung cancer: what is the link? (Xiong D, Wang Y, You M) Future Oncol 2015;11(12):1707-10 PMID: 26075437 SCOPUS ID: 2-s2.0-84931479471 06/16/2015       2 Citations
  • Inhibition of IGF1R signaling abrogates resistance to afatinib (BIBW2992) in EGFR T790M mutant lung cancer cells. (Lee Y, Wang Y, James M, Jeong JH, You M) Mol Carcinog 2016 May;55(5):991-1001 PMID: 26052929 PMCID: PMC6003619 SCOPUS ID: 2-s2.0-84930532549 06/09/2015       29 Citations
  • Functional characterization of RAD52 as a lung cancer susceptibility gene in the 12p13.33 locus. (Lieberman R, Xiong D, James M, Han Y, Amos CI, Wang L, You M) Mol Carcinog 2016 May;55(5):953-63 PMID: 26013599 PMCID: PMC4662629 SCOPUS ID: 2-s2.0-84930260740 05/28/2015       21 Citations
  • Enhanced antitumor activity of 3-bromopyruvate in combination with rapamycin in vivo and in vitro. (Zhang Q, Pan J, Lubet RA, Komas SM, Kalyanaraman B, Wang Y, You M) Cancer Prev Res (Phila) 2015 Apr;8(4):318-26 PMID: 25644152 PMCID: PMC6004825 SCOPUS ID: 2-s2.0-84927674589 02/04/2015       11 Citations
  • A recurrent mutation in PARK2 is associated with familial lung cancer. (Xiong D, Wang Y, Kupert E, Simpson C, Pinney SM, Gaba CR, Mandal D, Schwartz AG, Yang P, de Andrade M, Pikielny C, Byun J, Li Y, Stambolian D, Spitz MR, Liu Y, Amos CI, Bailey-Wilson JE, Anderson M, You M) Am J Hum Genet 2015 Feb 05;96(2):301-8 PMID: 25640678 PMCID: PMC4320264 SCOPUS ID: 2-s2.0-84925106543 02/03/2015       36 Citations
  • Global molecular changes in rat livers treated with RXR agonists: a comparison using transcriptomics and proteomics (Vedell PT, Townsend RR, You M, Malone JP, Grubbs CJ, Bland KI, Muccio DD, Atigadda VR, Chen Y, Vignola K, Lubet RA) Pharmacology Research and Perspectives December 2014;2(6) SCOPUS ID: 2-s2.0-85011053039 12/01/2014    
  • Honokiol inhibits lung tumorigenesis through inhibition of mitochondrial function. (Pan J, Zhang Q, Liu Q, Komas SM, Kalyanaraman B, Lubet RA, Wang Y, You M) Cancer Prev Res (Phila) 2014 Nov;7(11):1149-59 PMID: 25245764 PMCID: PMC6010030 SCOPUS ID: 2-s2.0-84910118566 09/24/2014       24 Citations
  • Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention. (Zhang Q, Pan J, Lubet RA, Wang Y, You M) Mol Carcinog 2015 Jun;54 Suppl 1:E129-37 PMID: 25163779 SCOPUS ID: 2-s2.0-84931025987 08/29/2014       14 Citations
  • Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA. (Deng B, Molina J, Aubry MC, Sun Z, Wang L, Eckloff BW, Vasmatzis G, You M, Wieben ED, Jen J, Wigle DA, Yang P) Cell Biosci 2014;4:35 PMID: 25105010 PMCID: PMC4124500 08/12/2014    
  • Conserved recurrent gene mutations correlate with pathway deregulation and clinical outcomes of lung adenocarcinoma in never-smokers. (Sun Z, Wang L, Eckloff BW, Deng B, Wang Y, Wampfler JA, Jang J, Wieben ED, Jen J, You M, Yang P) BMC Med Genomics 2014 Jun 04;7:32 PMID: 24894543 PMCID: PMC4060138 SCOPUS ID: 2-s2.0-84902810152 06/05/2014       32 Citations
  • Genome-wide association tests of inversions with application to psoriasis. (Ma J, Xiong M, You M, Lozano G, Amos CI) Hum Genet 2014 Aug;133(8):967-74 PMID: 24623382 PMCID: PMC4281304 SCOPUS ID: 2-s2.0-84904414489 03/14/2014       7 Citations
  • Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer. (Morrison CD, Liu P, Woloszynska-Read A, Zhang J, Luo W, Qin M, Bshara W, Conroy JM, Sabatini L, Vedell P, Xiong D, Liu S, Wang J, Shen H, Li Y, Omilian AR, Hill A, Head K, Guru K, Kunnev D, Leach R, Eng KH, Darlak C, Hoeflich C, Veeranki S, Glenn S, You M, Pruitt SC, Johnson CS, Trump DL) Proc Natl Acad Sci U S A 2014 Feb 11;111(6):E672-81 PMID: 24469795 PMCID: PMC3926024 SCOPUS ID: 2-s2.0-84893848638 01/29/2014       62 Citations
  • The use of mouse models for lung cancer chemoprevention studies (Wang Y, You MS, Rouggly LC, You M) Methods in Pharmacology and Toxicology 2014:135-153 SCOPUS ID: 2-s2.0-84891802000 01/13/2014    
  • CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis. (James MA, Vikis HG, Tate E, Rymaszewski AL, You M) Cancer Res 2014 Feb 15;74(4):1116-27 PMID: 24366883 PMCID: PMC6005686 SCOPUS ID: 2-s2.0-84894226710 12/25/2013       37 Citations
  • Transcriptomic analysis by RNA-seq reveals AP-1 pathway as key regulator that green tea may rely on to inhibit lung tumorigenesis. (Pan J, Zhang Q, Xiong D, Vedell P, Yan Y, Jiang H, Cui P, Ding F, Tichelaar JW, Wang Y, Lubet RA, You M) Mol Carcinog 2014 Jan;53(1):19-29 PMID: 24343902 12/18/2013    
  • EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. (Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL) Oncogene 2014 Sep 04;33(36):4464-73 PMID: 24096489 PMCID: PMC4527534 SCOPUS ID: 2-s2.0-84884967805 10/08/2013       23 Citations
  • Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1. (Shoghi KI, Xu J, Su Y, He J, Rowland D, Yan Y, Garbow JR, Tu Z, Jones LA, Higashikubo R, Wheeler KT, Lubet RA, Mach RH, You M) PLoS One 2013;8(9):e74188 PMID: 24073202 PMCID: PMC3779213 SCOPUS ID: 2-s2.0-84884477756 09/28/2013       35 Citations
  • Concordant effects of aromatase inhibitors on gene expression in ER+ Rat and human mammary cancers and modulation of the proteins coded by these genes. (Lu Y, You M, Ghazoui Z, Liu P, Vedell PT, Wen W, Bode AM, Grubbs CJ, Lubet RA) Cancer Prev Res (Phila) 2013 Nov;6(11):1151-61 PMID: 24067424 PMCID: PMC3874590 SCOPUS ID: 2-s2.0-84887878472 09/27/2013       8 Citations
  • Driver genes as targets for lung cancer prevention and treatment (Xiong D, Osarogiagbon RU, Wang Y, You M) Progress in Chemistry September 2013;25(9):1517-1525 SCOPUS ID: 2-s2.0-84885357707 09/01/2013    
  • Chemoprevention of oral cancer by a mixture of Chinese herbs (anti-tumor mixture B) (Wang Y, You M) Progress in Chemistry September 2013;25(9):1594-1600 SCOPUS ID: 2-s2.0-84885348657 09/01/2013    
  • Chemoprevention of lung squamous cell carcinoma by ginseng. (Pan J, Zhang Q, Li K, Liu Q, Wang Y, You M) Cancer Prev Res (Phila) 2013 Jun;6(6):530-9 PMID: 23550152 SCOPUS ID: 2-s2.0-84878883346 04/04/2013       10 Citations
  • Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR. (Kilari S, Remadevi I, Zhao B, Pan J, Miao R, Ramchandran R, North PE, You M, Rahimi N, Wilkinson GA) J Biol Chem 2013 Apr 12;288(15):10265-74 PMID: 23393131 PMCID: PMC3624410 SCOPUS ID: 2-s2.0-84876229992 02/09/2013       12 Citations
  • Effects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin (Bexarotene). (Vedell PT, Lu Y, Grubbs CJ, Yin Y, Jiang H, Bland KI, Muccio DD, Cvetkovic D, You M, Lubet R) Mol Pharmacol 2013 Mar;83(3):698-708 PMID: 23292798 PMCID: PMC3583492 SCOPUS ID: 2-s2.0-84874316155 01/08/2013       23 Citations
  • Mouse models of lung squamous cell carcinomas. (You MS, Rouggly LC, You M, Wang Y) Cancer Metastasis Rev 2013 Jun;32(1-2):77-82 PMID: 23229817 SCOPUS ID: 2-s2.0-84878115679 12/12/2012       8 Citations
  • Lung cancer chemoprevention: difficulties, promise and potential agents? (Dragnev K, You M, Wang Y, Lubet R) Expert Opin Investig Drugs 2013 Jan;22(1):35-47 PMID: 23167766 SCOPUS ID: 2-s2.0-84871001179 11/22/2012       18 Citations
  • Genomic landscape of non-small cell lung cancer in smokers and never-smokers. (Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, Maher CA, Fulton R, Fulton L, Wallis J, Chen K, Walker J, McDonald S, Bose R, Ornitz D, Xiong D, You M, Dooling DJ, Watson M, Mardis ER, Wilson RK) Cell 2012 Sep 14;150(6):1121-34 PMID: 22980976 PMCID: PMC3656590 SCOPUS ID: 2-s2.0-84866434919 09/18/2012       744 Citations
  • Strain-specific variation in murine natural killer gene complex contributes to differences in immunosurveillance for urethane-induced lung cancer. (Kreisel D, Gelman AE, Higashikubo R, Lin X, Vikis HG, White JM, Toth KA, Deshpande C, Carreno BM, You M, Taffner SM, Yokoyama WM, Bui JD, Schreiber RD, Krupnick AS) Cancer Res 2012 Sep 01;72(17):4311-7 PMID: 22751136 PMCID: PMC3432713 SCOPUS ID: 2-s2.0-84865794098 07/04/2012       18 Citations
  • WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury. (Li HH, Li Q, Liu P, Liu Y, Li J, Wasserloos K, Chao W, You M, Oury TD, Chhinder S, Hackam DJ, Billiar TR, Leikauf GD, Pitt BR, Zhang LM) Am J Respir Cell Mol Biol 2012 Oct;47(4):528-35 PMID: 22700866 PMCID: PMC3488625 SCOPUS ID: 2-s2.0-84867025205 06/16/2012       26 Citations
  • Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients. (Xiong D, Li G, Li K, Xu Q, Pan Z, Ding F, Vedell P, Liu P, Cui P, Hua X, Jiang H, Yin Y, Zhu Z, Li X, Zhang B, Ma D, Wang Y, You M) Carcinogenesis 2012 Sep;33(9):1797-805 PMID: 22696596 PMCID: PMC3514907 SCOPUS ID: 2-s2.0-84865569656 06/15/2012       35 Citations
  • Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus. (James MA, Wen W, Wang Y, Byers LA, Heymach JV, Coombes KR, Girard L, Minna J, You M) PLoS One 2012;7(6):e36116 PMID: 22675468 PMCID: PMC3366984 SCOPUS ID: 2-s2.0-84861899749 06/08/2012       66 Citations
  • Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. (Liu P, Morrison C, Wang L, Xiong D, Vedell P, Cui P, Hua X, Ding F, Lu Y, James M, Ebben JD, Xu H, Adjei AA, Head K, Andrae JW, Tschannen MR, Jacob H, Pan J, Zhang Q, Van den Bergh F, Xiao H, Lo KC, Patel J, Richmond T, Watt MA, Albert T, Selzer R, Anderson M, Wang J, Wang Y, Starnes S, Yang P, You M) Carcinogenesis 2012 Jul;33(7):1270-6 PMID: 22510280 PMCID: PMC3499051 SCOPUS ID: 2-s2.0-84865168855 04/19/2012       130 Citations
  • Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-induced lung tumorigenesis through apoptosis. (Zhang Q, Pan J, Wang Y, Lubet R, You M) Mol Carcinog 2013 Sep;52(9):686-91 PMID: 22456940 SCOPUS ID: 2-s2.0-84881612712 03/30/2012       18 Citations
  • Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity. (Zhang Q, Pan J, North PE, Yang S, Lubet RA, Wang Y, You M) Cancer Prev Res (Phila) 2012 May;5(5):717-25 PMID: 22401980 SCOPUS ID: 2-s2.0-84866260153 03/10/2012       29 Citations
  • MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. (Lu Y, Govindan R, Wang L, Liu PY, Goodgame B, Wen W, Sezhiyan A, Pfeifer J, Li YF, Hua X, Wang Y, Yang P, You M) Carcinogenesis 2012 May;33(5):1046-54 PMID: 22331473 PMCID: PMC3334512 SCOPUS ID: 2-s2.0-84860466755 02/15/2012       114 Citations
  • Gene-expression signature predicts postoperative recurrence in stage I non-small cell lung cancer patients. (Lu Y, Wang L, Liu P, Yang P, You M) PLoS One 2012;7(1):e30880 PMID: 22292069 PMCID: PMC3264655 SCOPUS ID: 2-s2.0-84856116589 02/01/2012       30 Citations
  • Quantitative monitoring of mouse lung tumors by magnetic resonance imaging. (Krupnick AS, Tidwell VK, Engelbach JA, Alli VV, Nehorai A, You M, Vikis HG, Gelman AE, Kreisel D, Garbow JR) Nat Protoc 2012 Jan 05;7(1):128-42 PMID: 22222788 PMCID: PMC3870466 SCOPUS ID: 2-s2.0-84861124351 01/10/2012       27 Citations
  • Animal models of lung cancer characterization and use for chemoprevention research. (Wang Y, Rouggly L, You M, Lubet R) Prog Mol Biol Transl Sci 2012;105:211-26 PMID: 22137433 12/06/2011       14 Citations
  • Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice. (Liu P, Lu Y, Liu H, Wen W, Jia D, Wang Y, You M) Mol Cancer Res 2012 Jan;10(1):66-74 PMID: 22127497 SCOPUS ID: 2-s2.0-84862934081 12/01/2011       21 Citations
  • Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis. (Wang Y, Yao R, Gao S, Wen W, Du Y, Szabo E, Hu M, Lubet RA, You M) Mol Carcinog 2013 Jan;52(1):49-56 PMID: 22086836 SCOPUS ID: 2-s2.0-84871344756 11/17/2011       14 Citations
  • Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. (Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M) Mol Carcinog 2012 Dec;51(12):993-1002 PMID: 22006501 PMCID: PMC3389580 SCOPUS ID: 2-s2.0-84867746013 10/19/2011       13 Citations
  • Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer. (Lu Y, Liu P, Van den Bergh F, Zellmer V, James M, Wen W, Grubbs CJ, Lubet RA, You M) Cancer Prev Res (Phila) 2012 Feb;5(2):248-59 PMID: 21982874 SCOPUS ID: 2-s2.0-84863237623 10/11/2011       13 Citations
  • Principles for the post-GWAS functional characterization of cancer risk loci. (Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG) Nat Genet 2011 Jun;43(6):513-8 PMID: 21614091 PMCID: PMC3325768 SCOPUS ID: 2-s2.0-79957604678 05/27/2011       281 Citations
  • Chemoprevention of lung carcinogenesis by the combination of aerosolized budesonide and oral pioglitazone in A/J mice. (Fu H, Zhang J, Pan J, Zhang Q, Lu Y, Wen W, Lubet RA, Szabo E, Chen R, Wang Y, Chen DR, You M) Mol Carcinog 2011 Dec;50(12):913-21 PMID: 21374736 PMCID: PMC6015734 SCOPUS ID: 2-s2.0-80155129711 03/05/2011       28 Citations
  • Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers. (Lubet RA, Lu Y, Bode AM, You M, Verney ZM, Steele VE, Townsend R, Juliana MM, Grubbs CJ) Oncol Rep 2011 May;25(5):1389-97 PMID: 21369704 SCOPUS ID: 2-s2.0-79953049622 03/04/2011       8 Citations
  • Cross-species comparison of orthologous gene expression in human bladder cancer and carcinogen-induced rodent models (Lu Y, Liu P, Wen W, Grubbs CJ, Townsend RR, Malone JP, Lubet RA, You M) American Journal of Translational Research 2011;3(1):8-27 SCOPUS ID: 2-s2.0-78650204545 01/01/2011    
  • Aerosolized bexarotene inhibits lung tumorigenesis without increasing plasma triglyceride and cholesterol levels in mice. (Zhang Q, Pan J, Zhang J, Liu P, Chen R, Chen DR, Lubet R, Wang Y, You M) Cancer Prev Res (Phila) 2011 Feb;4(2):270-6 PMID: 21163938 SCOPUS ID: 2-s2.0-79551709612 12/18/2010       18 Citations
  • Cross-species comparison of orthologous gene expression in human bladder cancer and carcinogen-induced rodent models. (Lu Y, Liu P, Wen W, Grubbs CJ, Townsend RR, Malone JP, Lubet RA, You M) Am J Transl Res 2010 Sep 20;3(1):8-27 PMID: 21139803 PMCID: PMC2981423 12/09/2010    
  • Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis. (James MA, Fu H, Liu Y, Chen DR, You M) Mol Carcinog 2011 Jan;50(1):1-7 PMID: 21061266 PMCID: PMC6004604 SCOPUS ID: 2-s2.0-78650185177 11/10/2010       43 Citations
  • Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice. (Wang Y, James M, Wen W, Lu Y, Szabo E, Lubet RA, You M) Mol Cancer Ther 2010 Nov;9(11):3074-82 PMID: 21045137 SCOPUS ID: 2-s2.0-78649668811 11/04/2010       42 Citations
  • Ordered subset analysis identifies loci influencing lung cancer risk on chromosomes 6q and 12q. (Fang S, Pinney SM, Bailey-Wilson JE, de Andrade MA, Li Y, Kupert E, You M, Schwartz AG, Yang P, Anderson MW, Amos CI) Cancer Epidemiol Biomarkers Prev 2010 Dec;19(12):3157-66 PMID: 21030603 PMCID: PMC3249234 SCOPUS ID: 2-s2.0-78650380354 10/30/2010       6 Citations
  • A dominant-negative c-jun mutant inhibits lung carcinogenesis in mice. (Tichelaar JW, Yan Y, Tan Q, Wang Y, Estensen RD, Young MR, Colburn NH, Yin H, Goodin C, Anderson MW, You M) Cancer Prev Res (Phila) 2010 Sep;3(9):1148-56 PMID: 20716630 PMCID: PMC2933283 SCOPUS ID: 2-s2.0-77956408222 08/19/2010       9 Citations
  • Functional genomics of chlorine-induced acute lung injury in mice. (Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Brant KA, Dopico RA, Di YP, Jang AS, Dietsch M, Medvedovic M, Li Q, Vuga LJ, Kaminski N, You M, Prows DR) Proc Am Thorac Soc 2010 Jul;7(4):294-6 PMID: 20601635 PMCID: PMC3136967 SCOPUS ID: 2-s2.0-77957903593 07/06/2010       8 Citations
  • Strain-specific susceptibility for pulmonary metastasis of sarcoma 180 cells in inbred mice. (Vikis HG, Jackson EN, Krupnick AS, Franklin A, Gelman AE, Chen Q, Piwnica-Worms D, You M) Cancer Res 2010 Jun 15;70(12):4859-67 PMID: 20501835 PMCID: PMC4690845 SCOPUS ID: 2-s2.0-77953758085 05/27/2010       8 Citations
  • A second genetic variant on chromosome 15q24-25.1 associates with lung cancer. (Liu P, Yang P, Wu X, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Spitz M, Amos CI, Anderson MW, You M) Cancer Res 2010 Apr 15;70(8):3128-35 PMID: 20395203 PMCID: PMC3378320 SCOPUS ID: 2-s2.0-77951049337 04/17/2010       4 Citations
  • A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers. (Amos CI, Pinney SM, Li Y, Kupert E, Lee J, de Andrade MA, Yang P, Schwartz AG, Fain PR, Gazdar A, Minna J, Wiest JS, Zeng D, Rothschild H, Mandal D, You M, Coons T, Gaba C, Bailey-Wilson JE, Anderson MW) Cancer Res 2010 Mar 15;70(6):2359-67 PMID: 20215501 PMCID: PMC2855643 SCOPUS ID: 2-s2.0-77950241825 03/11/2010       34 Citations
  • Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer. (Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW, You M) Cancer Epidemiol Biomarkers Prev 2010 Feb;19(2):517-24 PMID: 20142248 PMCID: PMC2846747 SCOPUS ID: 2-s2.0-76149107483 02/10/2010       24 Citations
  • Effect of dietary Polyphenon E and EGCG on lung tumorigenesis in A/J Mice. (Zhang Q, Fu H, Pan J, He J, Ryota S, Hara Y, Wang Y, Lubet RA, You M) Pharm Res 2010 Jun;27(6):1066-71 PMID: 20112129 PMCID: PMC6007862 SCOPUS ID: 2-s2.0-77953232664 01/30/2010       26 Citations
  • Preventive effects of bexarotene and budesonide in a genetically engineered mouse model of small cell lung cancer. (Wang Y, Wen W, Yi Y, Zhang Z, Lubet RA, You M) Cancer Prev Res (Phila) 2009 Dec;2(12):1059-64 PMID: 19934342 PMCID: PMC6001362 SCOPUS ID: 2-s2.0-76549125769 11/26/2009       25 Citations
  • Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor. (Lu Y, Liu P, James M, Vikis HG, Liu H, Wen W, Franklin A, You M) Oncogene 2010 Feb 18;29(7):1041-9 PMID: 19915612 PMCID: PMC6019621 SCOPUS ID: 2-s2.0-77149169733 11/17/2009       17 Citations
  • Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. (Liu Y, Liu P, Wen W, James MA, Wang Y, Bailey-Wilson JE, Amos CI, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Lee J, Seminara D, Minna J, Anderson MW, You M) Cancer Res 2009 Oct 01;69(19):7844-50 PMID: 19789337 PMCID: PMC2846106 SCOPUS ID: 2-s2.0-70350215708 10/01/2009       37 Citations
  • Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element. (Lubet RA, Yao R, Grubbs CJ, You M, Wang Y) Chem Biol Interact 2009 Nov 10;182(1):22-8 PMID: 19695238 PMCID: PMC3642098 SCOPUS ID: 2-s2.0-70349627876 08/22/2009       12 Citations
  • Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus. (Liu PY, Vikis H, James M, Lu Y, Wang DL, Liu HB, Wen WD, Wang Y, You M) Cancer Res 2009 Aug 01;69(15):6290-8 PMID: 19622765 SCOPUS ID: 2-s2.0-68049120471 07/23/2009       6 Citations
  • Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs. (Wang Y, Zhang Z, Garbow JR, Rowland DJ, Lubet RA, Sit D, Law F, You M) Cancer Prev Res (Phila) 2009 Jul;2(7):634-40 PMID: 19584077 PMCID: PMC3890236 SCOPUS ID: 2-s2.0-69249162699 07/09/2009       29 Citations
  • Lung cancer inhibitory effect of epigallocatechin-3-gallate is dependent on its presence in a complex mixture (polyphenon E). (Fu H, He J, Mei F, Zhang Q, Hara Y, Ryota S, Lubet RA, Chen R, Chen DR, You M) Cancer Prev Res (Phila) 2009 Jun;2(6):531-7 PMID: 19470785 SCOPUS ID: 2-s2.0-68949180099 05/28/2009       35 Citations
  • Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. (Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, Steinbach JH, Stitzel JA, Anderson MW, You M, Stevens VL, Bierut LJ, Goate AM, COGEND collaborators and GELCC collaborators) Hum Mol Genet 2009 Aug 15;18(16):3125-35 PMID: 19443489 PMCID: PMC2714722 SCOPUS ID: 2-s2.0-68049090045 05/16/2009       135 Citations
  • Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. (You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, Zheng W, Shu XO, Long J, Gao YT, Xiang YB, Chow WH, Rothman N, Petersen GM, de Andrade M, Wu Y, Cunningham JM, Wiest JS, Fain PR, Schwartz AG, Girard L, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW) Clin Cancer Res 2009 Apr 15;15(8):2666-74 PMID: 19351763 PMCID: PMC2746091 SCOPUS ID: 2-s2.0-65249131768 04/09/2009       59 Citations
  • RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway. (James MA, Lu Y, Liu Y, Vikis HG, You M) Cancer Res 2009 Mar 01;69(5):2108-16 PMID: 19244110 PMCID: PMC2746047 SCOPUS ID: 2-s2.0-62449130006 02/27/2009       65 Citations
  • Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. (Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M) J Natl Cancer Inst 2008 Sep 17;100(18):1326-30 PMID: 18780872 PMCID: PMC2538550 SCOPUS ID: 2-s2.0-52449127998 09/11/2008       113 Citations
  • Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice. (Anderson MW, Goodin C, Zhang Y, Kim S, Estensen RD, Wiedmann TS, Sekar P, Buncher CR, Khoury JC, Garbow JR, You M, Tichelaar JW) Carcinogenesis 2008 Aug;29(8):1594-600 PMID: 18515278 PMCID: PMC2516483 SCOPUS ID: 2-s2.0-49649102417 06/03/2008       24 Citations
  • Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging. (Garbow JR, Wang M, Wang Y, Lubet RA, You M) Clin Cancer Res 2008 Mar 01;14(5):1363-7 PMID: 18316556 SCOPUS ID: 2-s2.0-40949105107 03/05/2008       26 Citations
  • Enhanced susceptibility to chemical induction of ovarian tumors in mice with a germ line p53 mutation. (Wang Y, Zhang Z, Lu Y, Yao R, Jia D, Wen W, LaRegina M, Crist K, Lubet R, You M) Mol Cancer Res 2008 Jan;6(1):99-109 PMID: 18234966 SCOPUS ID: 2-s2.0-40749088488 02/01/2008       8 Citations
  • Common human cancer genes discovered by integrated gene-expression analysis. (Lu Y, Yi Y, Liu P, Wen W, James M, Wang D, You M) PLoS One 2007 Nov 07;2(11):e1149 PMID: 17989776 PMCID: PMC2065803 SCOPUS ID: 2-s2.0-41149106140 11/09/2007       61 Citations
  • Degradation of lung adenoma susceptibility 1, a major candidate mouse lung tumor modifier, is required for cell cycle progression. (Liu Y, Vikis HG, Yi Y, Futamura M, Wang Y, You M) Cancer Res 2007 Nov 01;67(21):10207-13 PMID: 17974961 SCOPUS ID: 2-s2.0-35948986310 11/03/2007       3 Citations
  • Enhanced lung tumor development in tobacco smoke-exposed p53 transgenic and Kras2 heterozygous deficient mice. (Yan Y, Tan Q, Wang Y, Wang D, Jin M, Gordon T, Lubet RA, You M) Inhal Toxicol 2007;19 Suppl 1:183-7 PMID: 17886066 SCOPUS ID: 2-s2.0-34548852256 10/04/2007       2 Citations
  • Large-scale in silico mapping of complex quantitative traits in inbred mice. (Liu P, Vikis H, Lu Y, Wang D, You M) PLoS One 2007 Jul 25;2(7):e651 PMID: 17653278 PMCID: PMC1920557 SCOPUS ID: 2-s2.0-38549083432 07/27/2007       31 Citations
  • Chemopreventive effect of aerosolized polyphenon E on lung tumorigenesis in A/J mice. (Yan Y, Cook J, McQuillan J, Zhang G, Hitzman CJ, Wang Y, Wiedmann TS, You M) Neoplasia 2007 May;9(5):401-5 PMID: 17534445 PMCID: PMC1877981 SCOPUS ID: 2-s2.0-34249002243 05/31/2007       38 Citations
  • EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. (Vikis H, Sato M, James M, Wang D, Wang Y, Wang M, Jia D, Liu Y, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Viswanathan A, Govindan R, Minna J, Anderson MW, You M) Cancer Res 2007 May 15;67(10):4665-70 PMID: 17510392 PMCID: PMC3460269 SCOPUS ID: 2-s2.0-34250329445 05/19/2007       76 Citations
  • Gene expression profiling of chemically induced rat bladder tumors. (Yao R, Yi Y, Grubbs CJ, Lubet RA, You M) Neoplasia 2007 Mar;9(3):207-21 PMID: 17401461 PMCID: PMC1838579 SCOPUS ID: 2-s2.0-33947375580 04/03/2007       28 Citations
  • Fine mapping and candidate gene analyses of pulmonary adenoma resistance 1, a major genetic determinant of mouse lung adenoma resistance. (Wang M, Zhang Z, Zhang Z, Vikis H, Yan Y, Wang Y, You M) Cancer Res 2007 Mar 15;67(6):2508-16 PMID: 17363568 SCOPUS ID: 2-s2.0-34047274647 03/17/2007       5 Citations
  • Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1. (Wang M, Vikis HG, Wang Y, Jia D, Wang D, Bierut LJ, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Minna J, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Liu Y, Viswanathan A, Govindan R, Anderson MW, You M) Cancer Res 2007 Jan 01;67(1):93-9 PMID: 17210687 PMCID: PMC3461257 SCOPUS ID: 2-s2.0-33846408685 01/11/2007       25 Citations
  • Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer. (Yan Y, Lu Y, Wang M, Vikis H, Yao R, Wang Y, Lubet RA, You M) Mol Cancer Res 2006 Dec;4(12):971-81 PMID: 17189387 SCOPUS ID: 2-s2.0-33846274624 12/26/2006       27 Citations
  • TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. (Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, Yang Q, Bennett C, Harada Y, Stankunas K, Wang CY, He X, MacDougald OA, You M, Williams BO, Guan KL) Cell 2006 Sep 08;126(5):955-68 PMID: 16959574 SCOPUS ID: 2-s2.0-33748153690 09/09/2006       876 Citations
  • Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. (Liu P, Wang Y, Vikis H, Maciag A, Wang D, Lu Y, Liu Y, You M) Nat Genet 2006 Aug;38(8):888-95 PMID: 16862160 SCOPUS ID: 2-s2.0-33746556713 07/25/2006       65 Citations
  • p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer. (Zhang Z, Wang Y, Yao R, Li J, Lubet RA, You M) Mol Cancer Res 2006 Jun;4(6):401-10 PMID: 16778087 SCOPUS ID: 2-s2.0-33745823859 06/17/2006       19 Citations
  • Organ-specific expression profiles of rat mammary gland, liver, and lung tissues treated with targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide. (Wang Y, Yao R, Maciag A, Grubbs CJ, Lubet RA, You M) Mol Cancer Ther 2006 Apr;5(4):1060-72 PMID: 16648578 SCOPUS ID: 2-s2.0-33646581670 05/02/2006       22 Citations
  • Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. (Yan Y, Wang Y, Tan Q, Hara Y, Yun TK, Lubet RA, You M) Neoplasia 2006 Jan;8(1):52-8 PMID: 16533426 PMCID: PMC1584290 SCOPUS ID: 2-s2.0-33646400002 03/15/2006       49 Citations
  • A gene expression signature that can predict green tea exposure and chemopreventive efficacy of lung cancer in mice. (Lu Y, Yao R, Yan Y, Wang Y, Hara Y, Lubet RA, You M) Cancer Res 2006 Feb 15;66(4):1956-63 PMID: 16488994 SCOPUS ID: 2-s2.0-33644515956 02/21/2006       33 Citations
  • Chemoprevention of lung cancer by tea. (Clark J, You M) Mol Nutr Food Res 2006 Feb;50(2):144-51 PMID: 16425282 SCOPUS ID: 2-s2.0-33644655151 01/21/2006       64 Citations
  • Efficacy of the farnesyltransferase inhibitor R115777 in a rat mammary tumor model: role of Ha-ras mutations and use of microarray analysis in identifying potential targets. (Yao R, Wang Y, Lu Y, Lemon WJ, End DW, Grubbs CJ, Lubet RA, You M) Carcinogenesis 2006 Jul;27(7):1420-31 PMID: 16403772 SCOPUS ID: 2-s2.0-33745630950 01/13/2006       8 Citations
  • Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. (Yan Y, Wang Y, Tan Q, Lubet RA, You M) Neoplasia 2005 Dec;7(12):1053-7 PMID: 16354587 PMCID: PMC1501176 SCOPUS ID: 2-s2.0-33644874504 12/16/2005       39 Citations
  • Induction of invasive mouse skin carcinomas in transgenic mice with mutations in both H-ras and p53. (Zhang Z, Yao R, Li J, Wang Y, Boone CW, Lubet RA, You M) Mol Cancer Res 2005 Oct;3(10):563-74 PMID: 16254190 SCOPUS ID: 2-s2.0-27644506100 10/29/2005       14 Citations
  • Prevention of lung cancer progression by bexarotene in mouse models. (Wang Y, Zhang Z, Yao R, Jia D, Wang D, Lubet RA, You M) Oncogene 2006 Mar 02;25(9):1320-9 PMID: 16247446 SCOPUS ID: 2-s2.0-33644783537 10/26/2005       29 Citations
  • A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice. (Wang Y, Zhang Z, Lubet RA, You M) Oncogene 2006 Feb 23;25(8):1277-80 PMID: 16247444 SCOPUS ID: 2-s2.0-33644504228 10/26/2005       15 Citations
  • Five loci, SLT1 to SLT5, controlling the susceptibility to spontaneously occurring lung cancer in mice. (Wang D, You M) Cancer Res 2005 Sep 15;65(18):8158-65 PMID: 16166290 SCOPUS ID: 2-s2.0-24944537379 09/17/2005       8 Citations
  • A moderate reduction of Bcl-x(L) expression protects against tumorigenesis; however, it also increases susceptibility to tissue injury. (Henderson CC, Zhang Z, Manson SR, Riehm JJ, Kataoka M, Flye MW, Garbow JR, You M, Weintraub SJ) Oncogene 2005 Oct 27;24(47):7120-4 PMID: 16007126 SCOPUS ID: 2-s2.0-27644564949 07/12/2005       4 Citations
  • Tobacco smoke-induced lung tumorigenesis in mutant A/J mice with alterations in K-ras, p53, or Ink4a/Arf. (Wang Y, Zhang Z, Lubet R, You M) Oncogene 2005 Apr 21;24(18):3042-9 PMID: 15846305 SCOPUS ID: 2-s2.0-18344371925 04/23/2005       31 Citations
  • Characterization of two protein-binding sites in the second intron of the mouse K-ras gene. (Chen B, Wang Y, You M) Exp Lung Res 2005 Mar;31(2):179-92 PMID: 15824020 SCOPUS ID: 2-s2.0-14644396598 04/13/2005    
  • Identification of genetic polymorphisms through comparative DNA sequence analysis on the K-ras gene: implications for lung tumor susceptibility. (Wang M, Wang Y, You M) Exp Lung Res 2005 Mar;31(2):165-77 PMID: 15824019 SCOPUS ID: 2-s2.0-14644388822 04/13/2005       3 Citations
  • K-ras mutations in lung tumors from p53 mutant mice exposed to cigarette smoke. (Yao R, Wang Y, D'Agostini F, Izzotti A, Lubet RA, You M, De Flora S) Exp Lung Res 2005 Mar;31(2):271-81 PMID: 15824025 SCOPUS ID: 2-s2.0-14644435150 04/13/2005       19 Citations
  • Induction and modulation of lung tumors: genomic and transcriptional alterations in cigarette smoke-exposed mice. (De Flora S, Izzotti A, D'Agostini F, Bennicelli C, You M, Lubet RA, Balansky RM) Exp Lung Res 2005 Jan-Feb;31(1):19-35 PMID: 15765917 SCOPUS ID: 2-s2.0-11144225084 03/16/2005       17 Citations
  • Mouse models incorporating alterations in the major tumor suppressor genes P53 and P16: their use in screening for potential carcinogens, developing further relevant mouse models, and screening for potential chemopreventive and chemotherapetutic agents. (Lubet R, Wang Y, Zhang Z, You M) Exp Lung Res 2005 Jan-Feb;31(1):117-33 PMID: 15765922 SCOPUS ID: 2-s2.0-11144228245 03/16/2005       12 Citations
  • Characterization of rat ovarian adenocarcinomas developed in response to direct instillation of 7,12-dimethylbenz[a]anthracene (DMBA) coated suture. (Crist KA, Zhang Z, You M, Gunning WT, Conran PB, Steele VE, Lubet RA) Carcinogenesis 2005 May;26(5):951-7 PMID: 15695234 SCOPUS ID: 2-s2.0-19844377613 02/08/2005       24 Citations
  • Pas1c1 is a candidate for the mouse pulmonary adenoma susceptibility 1 locus. (Wang M, Futamura M, Wang Y, You M) Oncogene 2005 Mar 10;24(11):1958-63 PMID: 15688036 SCOPUS ID: 2-s2.0-16244410135 02/03/2005       7 Citations
  • Tumor susceptibility of Rassf1a knockout mice. (Tommasi S, Dammann R, Zhang Z, Wang Y, Liu L, Tsark WM, Wilczynski SP, Li J, You M, Pfeifer GP) Cancer Res 2005 Jan 01;65(1):92-8 PMID: 15665283 SCOPUS ID: 2-s2.0-19944429131 01/25/2005       176 Citations
  • Modeling human lung cancer in mice: 4th International Mouse Lung Tumorigenesis Symposium (Jacks T, You M, Malkinson AM, Dragani TA) Experimental Lung Research January 2005;31(1):1-2 SCOPUS ID: 2-s2.0-11144234505 01/01/2005    
  • Gene expression in the lung of p53 mutant mice exposed to cigarette smoke. (Izzotti A, Cartiglia C, Longobardi M, Bagnasco M, Merello A, You M, Lubet RA, De Flora S) Cancer Res 2004 Dec 01;64(23):8566-72 PMID: 15574763 SCOPUS ID: 2-s2.0-9244260573 12/03/2004       37 Citations
  • Altered gene expression profile in mouse bladder cancers induced by hydroxybutyl(butyl)nitrosamine. (Yao R, Lemon WJ, Wang Y, Grubbs CJ, Lubet RA, You M) Neoplasia 2004 Sep-Oct;6(5):569-77 PMID: 15548366 PMCID: PMC1531661 SCOPUS ID: 2-s2.0-6944225349 11/19/2004       26 Citations
  • Budesonide exerts its chemopreventive efficacy during mouse lung tumorigenesis by modulating gene expressions. (Yao R, Wang Y, Lemon WJ, Lubet RA, You M) Oncogene 2004 Oct 07;23(46):7746-52 PMID: 15361829 SCOPUS ID: 2-s2.0-7044247179 09/14/2004       42 Citations
  • A major lung cancer susceptibility locus maps to chromosome 6q23-25. (Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Wiest JS, Fain P, Schwartz AG, You M, Franklin W, Klein C, Gazdar A, Rothschild H, Mandal D, Coons T, Slusser J, Lee J, Gaba C, Kupert E, Perez A, Zhou X, Zeng D, Liu Q, Zhang Q, Seminara D, Minna J, Anderson MW) Am J Hum Genet 2004 Sep;75(3):460-74 PMID: 15272417 PMCID: PMC1182024 07/24/2004    
  • Chemoprevention of lung cancer in transgenic mice. (Lubet RA, Zhang Z, Wang Y, You M) Chest 2004 May;125(5 Suppl):144S-7S PMID: 15136469 SCOPUS ID: 2-s2.0-2442536715 05/12/2004       10 Citations
  • Detection of primary lung tumors in rodents by magnetic resonance imaging. (Garbow JR, Zhang Z, You M) Cancer Res 2004 Apr 15;64(8):2740-2 PMID: 15087388 SCOPUS ID: 2-s2.0-9244262630 04/17/2004       42 Citations
  • Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia. (Wang M, Devereux TR, Vikis HG, McCulloch SD, Holliday W, Anna C, Wang Y, Bebenek K, Kunkel TA, Guan K, You M) Cancer Res 2004 Mar 15;64(6):1924-31 PMID: 15026325 SCOPUS ID: 2-s2.0-12144287580 03/18/2004       58 Citations
  • Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models. (Zhang Z, Wang Y, Yao R, Li J, Yan Y, La Regina M, Lemon WL, Grubbs CJ, Lubet RA, You M) Oncogene 2004 May 06;23(21):3841-50 PMID: 15021904 SCOPUS ID: 2-s2.0-2342622022 03/17/2004       52 Citations
  • CpG methylation in the Fhit regulatory region: relation to Fhit expression in murine tumors. (Han SY, Iliopoulos D, Druck T, Guler G, Grubbs CJ, Pereira M, Zhang Z, You M, Lubet RA, Fong LY, Huebner K) Oncogene 2004 May 13;23(22):3990-8 PMID: 15007387 SCOPUS ID: 2-s2.0-2542571001 03/10/2004       23 Citations
  • A chemically induced model for squamous cell carcinoma of the lung in mice: histopathology and strain susceptibility. (Wang Y, Zhang Z, Yan Y, Lemon WJ, LaRegina M, Morrison C, Lubet R, You M) Cancer Res 2004 Mar 01;64(5):1647-54 PMID: 14996723 SCOPUS ID: 2-s2.0-1642363983 03/05/2004       89 Citations
  • Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression. (Herzog CR, Bodon N, Pittman B, Maronpot RR, Massey TE, Anderson MW, You M, Devereux TR) Oncogene 2004 Apr 15;23(17):3033-9 PMID: 14755239 SCOPUS ID: 2-s2.0-2442490689 02/03/2004       17 Citations
  • Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas. (Bonner AE, Lemon WJ, Devereux TR, Lubet RA, You M) Oncogene 2004 Feb 05;23(5):1166-76 PMID: 14647414 SCOPUS ID: 2-s2.0-1442303214 12/03/2003       80 Citations
  • Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice. (Zhang Z, Futamura M, Vikis HG, Wang M, Li J, Wang Y, Guan KL, You M) Proc Natl Acad Sci U S A 2003 Oct 28;100(22):12642-7 PMID: 14583591 PMCID: PMC240671 SCOPUS ID: 2-s2.0-0242331667 10/30/2003       35 Citations
  • RASSF1A promoter methylation and Kras2 mutations in non small cell lung cancer. (Li J, Zhang Z, Dai Z, Popkie AP, Plass C, Morrison C, Wang Y, You M) Neoplasia 2003 Jul-Aug;5(4):362-6 PMID: 14511407 PMCID: PMC1550336 SCOPUS ID: 2-s2.0-0042856354 09/27/2003       25 Citations
  • Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf. (Zhang Z, Wang Y, Lantry LE, Kastens E, Liu G, Hamilton AD, Sebti SM, Lubet RA, You M) Oncogene 2003 Sep 18;22(40):6257-65 PMID: 13679864 SCOPUS ID: 2-s2.0-0142088857 09/19/2003       32 Citations
  • Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice. (Wang Y, Zhang Z, Kastens E, Lubet RA, You M) Cancer Res 2003 Aug 01;63(15):4389-95 PMID: 12907609 SCOPUS ID: 2-s2.0-0042090506 08/09/2003       60 Citations
  • Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. (Wang M, Lemon WJ, Liu G, Wang Y, Iraqi FA, Malkinson AM, You M) Cancer Res 2003 Jun 15;63(12):3317-24 PMID: 12810665 SCOPUS ID: 2-s2.0-0038068943 06/18/2003       38 Citations
  • Gene expression signatures identify novel regulatory pathways during murine lung development: implications for lung tumorigenesis. (Bonner AE, Lemon WJ, You M) J Med Genet 2003 Jun;40(6):408-17 PMID: 12807961 PMCID: PMC1735509 SCOPUS ID: 2-s2.0-0037531706 06/17/2003       57 Citations
  • Peroxisome proliferator-activated receptor alpha (PPARalpha) agonist treatment reverses PPARalpha dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice. (Fischer M, You M, Matsumoto M, Crabb DW) J Biol Chem 2003 Jul 25;278(30):27997-8004 PMID: 12791698 06/07/2003       203 Citations
  • Single nucleotide polymorphism (SNP) analysis of mouse pulmonary adenoma susceptibility loci 1-4 for identification of candidate genes. (Lemon WJ, Swinton CH, Wang M, Berbari N, Wang Y, You M) J Med Genet 2003 Apr;40(4):e36 PMID: 12676909 PMCID: PMC1735427 SCOPUS ID: 2-s2.0-0037389714 04/05/2003       8 Citations
  • Differential gene expression in chemically induced mouse lung adenomas. (Yao R, Wang Y, Lubet RA, You M) Neoplasia 2003 Jan-Feb;5(1):41-52 PMID: 12659669 PMCID: PMC1502122 SCOPUS ID: 2-s2.0-0037252353 03/28/2003       20 Citations
  • LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer. (Li J, Zhang Z, Dai Z, Plass C, Morrison C, Wang Y, Wiest JS, Anderson MW, You M) Oncogene 2003 Feb 27;22(8):1243-6 PMID: 12606951 PMCID: PMC3438910 SCOPUS ID: 2-s2.0-0037468253 02/28/2003       44 Citations
  • Cell proliferation, apoptosis, and expression of cyclin D1 and cyclin E as potential biomarkers in tamoxifen-treated mammary tumors. (Christov K, Ikui A, Shilkaitis A, Green A, Yao R, You M, Grubbs C, Steele V, Lubet R, Weinstein IB) Breast Cancer Res Treat 2003 Feb;77(3):253-64 PMID: 12602925 SCOPUS ID: 2-s2.0-12244279348 02/27/2003       29 Citations
  • Molecular alterations and lung tumors in p53 mutant mice exposed to cigarette smoke. (De Flora S, Balansky RM, D'Agostini F, Izzotti A, Camoirano A, Bennicelli C, Zhang Z, Wang Y, Lubet RA, You M) Cancer Res 2003 Feb 15;63(4):793-800 PMID: 12591728 SCOPUS ID: 2-s2.0-0037443032 02/20/2003       61 Citations
  • Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesis. (Herzog CR, Devereux TR, Pittman B, You M) Cancer Res 2002 Nov 15;62(22):6424-9 PMID: 12438228 SCOPUS ID: 2-s2.0-0037112437 11/20/2002       7 Citations
  • Linkage disequilibrium mapping of novel lung tumor susceptibility quantitative trait loci in mice. (Wang D, Lemon WJ, You M) Oncogene 2002 Oct 03;21(44):6858-65 PMID: 12360413 SCOPUS ID: 2-s2.0-0037015681 10/03/2002       12 Citations
  • Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays. (Lemon WJ, Bernert H, Sun H, Wang Y, You M) J Med Genet 2002 Sep;39(9):644-55 PMID: 12205107 PMCID: PMC1735228 SCOPUS ID: 2-s2.0-0036714665 09/03/2002       19 Citations
  • A strong candidate gene for the Papg1 locus on mouse chromosome 4 affecting lung tumor progression. (Zhang Z, Wang Y, Herzog CR, Liu G, Lee HW, DePinho RA, You M) Oncogene 2002 Aug 29;21(38):5960-6 PMID: 12185599 SCOPUS ID: 2-s2.0-0037194599 08/20/2002       17 Citations
  • Differentially expressed genes associated with mouse lung tumor progression. (Yao R, Wang Y, Lubet RA, You M) Oncogene 2002 Aug 22;21(37):5814-21 PMID: 12173053 SCOPUS ID: 2-s2.0-0037158893 08/13/2002       48 Citations
  • Erratum: Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells (Cancer Letters (2001) 168 (165-172) PII: S030438501004803) (Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM) Cancer Letters 28 June 2002;180(2):223 SCOPUS ID: 2-s2.0-0037189036 06/28/2002    
  • p53 transgenic mice are highly susceptible to 1, 2-dimethylhydrazine-induced uterine sarcomas. (Zhang Z, Li J, Lantry LE, Wang Y, Wiseman RW, Lubet RA, You M) Cancer Res 2002 Jun 01;62(11):3024-9 PMID: 12036908 SCOPUS ID: 2-s2.0-0036605992 05/31/2002       22 Citations
  • Detection of genomic alterations in human endometrial cancer by two-dimensional gel electrophoresis. (Pohlod-Miller S, Fanning J, Gu P, Crist KA, You M) Am J Obstet Gynecol 2002 May;186(5):855-7 PMID: 12015494 SCOPUS ID: 2-s2.0-0036583003 05/17/2002       1 Citation
  • Chromosome mapping and sequence variation of the murine Ras effector gene Nore1. (Yao R, Wang Y, You M) Cytogenet Cell Genet 2001;95(1-2):126-8 PMID: 11978988 SCOPUS ID: 2-s2.0-0035736059 04/30/2002    
  • Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas. (McDoniels-Silvers AL, Nimri CF, Stoner GD, Lubet RA, You M) Clin Cancer Res 2002 Apr;8(4):1127-38 PMID: 11948124 SCOPUS ID: 2-s2.0-0036554867 04/12/2002       135 Citations
  • Differential expression of critical cellular genes in human lung adenocarcinomas and squamous cell carcinomas in comparison to normal lung tissues. (McDoniels-Silvers AL, Stoner GD, Lubet RA, You M) Neoplasia 2002 Mar-Apr;4(2):141-50 PMID: 11896569 PMCID: PMC1550320 SCOPUS ID: 2-s2.0-0036122839 03/16/2002       36 Citations
  • Altered gene expression profile in chemically induced rat mammary adenocarcinomas and its modulation by an aromatase inhibitor. (Wang Y, Hu L, Yao R, Wang M, Crist KA, Grubbs CJ, Johanning GL, Lubet RA, You M) Oncogene 2001 Nov 22;20(53):7710-21 PMID: 11753649 SCOPUS ID: 2-s2.0-0035935978 12/26/2001       21 Citations
  • Wildtype Kras2 can inhibit lung carcinogenesis in mice. (Zhang Z, Wang Y, Vikis HG, Johnson L, Liu G, Li J, Anderson MW, Sills RC, Hong HL, Devereux TR, Jacks T, Guan KL, You M) Nat Genet 2001 Sep;29(1):25-33 PMID: 11528387 SCOPUS ID: 2-s2.0-17944369909 08/31/2001       233 Citations
  • Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells. (Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM) Cancer Lett 2001 Jul 26;168(2):165-72 PMID: 11403921 SCOPUS ID: 2-s2.0-0035954828 06/19/2001       10 Citations
  • Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas. (Herzog CR, Crist KA, Sabourin CL, Kelloff GJ, Boone CW, Stoner GD, You M) Mol Carcinog 2001 Mar;30(3):159-68 PMID: 11301476 SCOPUS ID: 2-s2.0-0035063353 04/13/2001       15 Citations
  • Inactivation of both Rb and p53 pathways in mouse lung epithelial cell lines. (McDoniels-Silvers AL, Herzog CR, Tyson FL, Malkinson AM, You M) Exp Lung Res 2001 Apr-May;27(3):297-318 PMID: 11293330 SCOPUS ID: 2-s2.0-0035083738 04/11/2001       15 Citations
  • Alternative splicing of the K-ras gene in mouse tissues and cell lines. (Wang Y, You M, Wang Y) Exp Lung Res 2001 Apr-May;27(3):255-67 PMID: 11293328 SCOPUS ID: 2-s2.0-0035080810 04/11/2001       25 Citations
  • Detection of differentially expressed genes in mouse lung adenocarcinomas. (Lin L, Wang Y, Bergman G, Kelloff GJ, Lubet RA, You M) Exp Lung Res 2001 Apr-May;27(3):217-29 PMID: 11293325 SCOPUS ID: 2-s2.0-0035083960 04/11/2001       15 Citations
  • Detection of genetic alterations in mouse lung adenocarcinomas by two-dimensional gel electrophoresis. (Liu J, Gu P, Bergman G, Kelloff GJ, Boone CW, You M, Wang Y) Exp Lung Res 2000 Dec;26(8):651-8 PMID: 11195462 SCOPUS ID: 2-s2.0-0034521636 02/24/2001       1 Citation
  • Chemopreventive efficacy of promising farnesyltransferase inhibitors. (Lantry LE, Zhang Z, Crist KA, Wang Y, Hara M, Zeeck A, Lubet RA, You M) Exp Lung Res 2000 Dec;26(8):773-90 PMID: 11195470 SCOPUS ID: 2-s2.0-0034525706 02/24/2001       21 Citations
  • Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis. (Yao R, Rioux N, Castonguay A, You M) Exp Lung Res 2000 Dec;26(8):731-42 PMID: 11195467 SCOPUS ID: 2-s2.0-0034525705 02/24/2001       69 Citations
  • Fine mapping and characterization of candidate lung tumor resistance genes for the Par2 locus on mouse chromosome 18. (Zhang Z, Lin L, Liu G, Wang M, Hill J, Wang Y, You M, Devereux TR) Exp Lung Res 2000 Dec;26(8):627-39 PMID: 11195460 SCOPUS ID: 2-s2.0-0034517980 02/24/2001       9 Citations
  • Use of p53 transgenic mice in the development of cancer models for multiple purposes. (Lubet RA, Zhang Z, Wiseman RW, You M) Exp Lung Res 2000 Dec;26(8):581-93 PMID: 11195457 SCOPUS ID: 2-s2.0-0034524155 02/24/2001       30 Citations
  • Bcl-2 and Bax are differentially expressed in hyperplastic, premalignant, and malignant lesions of mammary carcinogenesis. (Shilkaitis A, Graves J, Mehta RR, Hu L, You M, Lubet R, Steele V, Kelloff G, Christov K) Cell Growth Differ 2000 Aug;11(8):437-45 PMID: 10965848 SCOPUS ID: 2-s2.0-0033883688 08/31/2000       15 Citations
  • A germ-line p53 mutation accelerates pulmonary tumorigenesis: p53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin. (Zhang Z, Liu Q, Lantry LE, Wang Y, Kelloff GJ, Anderson MW, Wiseman RW, Lubet RA, You M) Cancer Res 2000 Feb 15;60(4):901-7 PMID: 10706103 SCOPUS ID: 2-s2.0-0034652597 03/08/2000       92 Citations
  • Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. (Lantry LE, Zhang Z, Yao R, Crist KA, Wang Y, Ohkanda J, Hamilton AD, Sebti SM, Lubet RA, You M) Carcinogenesis 2000 Jan;21(1):113-6 PMID: 10607742 SCOPUS ID: 2-s2.0-0033959438 12/23/1999       45 Citations
  • Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesis. (Herzog CR, Noh S, Lantry LE, Guan KL, You M) Mol Carcinog 1999 Jun;25(2):92-8 PMID: 10365910 SCOPUS ID: 2-s2.0-0032993060 06/12/1999       22 Citations
  • 5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model. (Lantry LE, Zhang Z, Crist KA, Wang Y, Kelloff GJ, Lubet RA, You M) Carcinogenesis 1999 Feb;20(2):343-6 PMID: 10069475 SCOPUS ID: 2-s2.0-0032905851 03/09/1999       57 Citations
  • Preclinical and clinical models of lung cancer chemoprevention. (You M, Bergman G) Hematol Oncol Clin North Am 1998 Oct;12(5):1037-53 PMID: 9888020 SCOPUS ID: 2-s2.0-0031718305 01/15/1999       48 Citations
  • At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice. (Festing MF, Lin L, Devereux TR, Gao F, Yang A, Anna CH, White CM, Malkinson AM, You M) Genomics 1998 Oct 15;53(2):129-36 PMID: 9790761 SCOPUS ID: 2-s2.0-0032532493 10/29/1998       61 Citations
  • Chemopreventive effects of the aromatase inhibitor vorozole (R 83842) in the methylnitrosourea-induced mammary cancer model. (Lubet RA, Steele VE, DeCoster R, Bowden C, You M, Juliana MM, Eto I, Kelloff GJ, Grubbs CJ) Carcinogenesis 1998 Aug;19(8):1345-51 PMID: 9744527 SCOPUS ID: 2-s2.0-0031682251 09/23/1998       34 Citations
  • Effect of green tea on p53 mutation distribution in ultraviolet B radiation-induced mouse skin tumors. (Liu Q, Wang Y, Crist KA, Wang ZY, Lou YR, Huang MT, Conney AH, You M) Carcinogenesis 1998 Jul;19(7):1257-62 PMID: 9683186 SCOPUS ID: 2-s2.0-0031902661 07/31/1998       26 Citations
  • Expression of cell cycle proteins in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumors. (Sabourin CL, Wang QS, Ralston SL, Evans J, Coate J, Herzog CR, Jones SL, Weghorst CM, Kelloff GJ, Lubet RA, You M, Stoner GD) Exp Lung Res 1998 Jul-Aug;24(4):499-521 PMID: 9659580 SCOPUS ID: 2-s2.0-15644373914 07/11/1998       22 Citations
  • Additional evidence that the K-ras protooncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene. (Lin L, Festing MF, Devereux TR, Crist KA, Christiansen SC, Wang Y, Yang A, Svenson K, Paigen B, Malkinson AM, You M) Exp Lung Res 1998 Jul-Aug;24(4):481-97 PMID: 9659579 SCOPUS ID: 2-s2.0-14444278728 07/11/1998       56 Citations
  • Modulation of methylnitrosourea-induced breast cancer in Sprague Dawley rats by dehydroepiandrosterone: dose-dependent inhibition, effects of limited exposure, effects on peroxisomal enzymes, and lack of effects on levels of Ha-Ras mutations. (Lubet RA, Gordon GB, Prough RA, Lei XD, You M, Wang Y, Grubbs CJ, Steele VE, Kelloff GJ, Thomas CF, Moon RD) Cancer Res 1998 Mar 01;58(5):921-6 PMID: 9500451 SCOPUS ID: 2-s2.0-0032031874 03/21/1998       37 Citations
  • Decreased expression of the adenomatous polyposis coli (Apc) and mutated in colorectal cancer (Mcc) genes in mouse lung neoplasia. (Oreffo VI, Robinson S, You M, Wu MC, Malkinson AM) Mol Carcinog 1998 Jan;21(1):37-49 PMID: 9473770 SCOPUS ID: 2-s2.0-0031932199 02/25/1998       17 Citations
  • Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genes. (Devereux TR, Anna CH, Patel AC, White CM, Festing MF, You M) Carcinogenesis 1997 Sep;18(9):1751-5 PMID: 9328171 SCOPUS ID: 2-s2.0-0031409641 11/05/1997       20 Citations
  • Tissue-specific expression of the K-ras allele from the A/J parent in (A/J x TSG-p53) F1 mice. (Matzinger SA, Chen B, Wang Y, Crist KA, Stoner GD, Kelloff GJ, Lubet RA, You M) Gene 1997 Apr 01;188(2):261-9 PMID: 9133601 SCOPUS ID: 2-s2.0-0030999105 04/01/1997       12 Citations
  • Effect of early vs. late administration of 4-hydroxyphenylretinamide (4-HPR) on N-methyl-N-nitrosourea (MNU)-induced mammary tumorigenesis. (Crist KA, Wang Y, Lubet RA, Steele VE, Kelloff GJ, You M) J Cell Biochem Suppl 1997;27:92-9 PMID: 9591198 SCOPUS ID: 2-s2.0-0031325821 01/01/1997       4 Citations
  • Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung. (Lantry LE, Zhang Z, Gao F, Crist KA, Wang Y, Kelloff GJ, Lubet RA, You M) J Cell Biochem Suppl 1997;27:20-5 PMID: 9591189 SCOPUS ID: 2-s2.0-0031321471 01/01/1997       40 Citations
  • Detection of differentially expressed genes in methylnitrosourea-induced rat mammary adenocarcinomas. (Hu L, Lin L, Crist KA, Kelloff GJ, Steele VE, Lubet RA, You M, Wang Y) J Cell Biochem Suppl 1997;28-29:117-24 PMID: 9589356 SCOPUS ID: 2-s2.0-0031401659 01/01/1997       5 Citations
  • Genetic alterations in mouse lung tumors: implications for cancer chemoprevention. (Herzog CR, Lubet RA, You M) J Cell Biochem Suppl 1997;28-29:49-63 PMID: 9589349 SCOPUS ID: 2-s2.0-0031401656 01/01/1997       51 Citations
  • Sequence variation and chromosomal mapping of the murine Cdkn2a tumor suppressor gene. (Herzog CR, You M) Mamm Genome 1997 Jan;8(1):65-6 PMID: 9021155 SCOPUS ID: 2-s2.0-0030631588 01/01/1997       18 Citations
  • The 5'-flanking region of the E1 alpha form of the murine p16INK4a (MTS1) gene. (Soloff EV, Herzog CR, You M) Gene 1996 Nov 21;180(1-2):213-5 PMID: 8973369 SCOPUS ID: 2-s2.0-0030597340 11/21/1996       3 Citations
  • Homozygous codeletion and differential decreased expression of p15INK4b, p16INK4a-alpha and p16INK4a-beta in mouse lung tumor cells. (Herzog CR, Soloff EV, McDoniels AL, Tyson FL, Malkinson AM, Haugen-Strano A, Wiseman RW, Anderson MW, You M) Oncogene 1996 Nov 07;13(9):1885-91 PMID: 8934534 SCOPUS ID: 2-s2.0-0029909822 11/07/1996       69 Citations
  • Loss of heterozygosity on chromosomes 1, 11, 12, and 14 in hybrid mouse lung adenocarcinomas. (Herzog CR, Chen B, Wang Y, Schut HA, You M) Mol Carcinog 1996 Jun;16(2):83-90 PMID: 8645430 SCOPUS ID: 2-s2.0-0029938898 06/01/1996       17 Citations
  • Detection of genomic alterations in human cervical cancer by two-dimensional gel electrophoresis. (Liu J, Wang Y, Gu P, Patrick J, Crist KA, Sabourin CL, Stoner GD, Mitchell MF, Fanning JD, Kim K, Goldblatt PJ, Kelloff GJ, Boone CW, You M) J Cell Biochem Suppl 1996;25:41-8 PMID: 9027597 SCOPUS ID: 2-s2.0-0030513704 01/01/1996       3 Citations
  • DNA quantification in cervical intraepithelial neoplasia thick tissue sections by confocal laser scanning microscopy. (Crist KA, Kim K, Goldblatt PJ, Boone CW, Kelloff GJ, You M) J Cell Biochem Suppl 1996;25:49-56 PMID: 9027598 SCOPUS ID: 2-s2.0-0030337852 01/01/1996       2 Citations
  • Allelic loss of distal chromosome 4 in mouse lung tumors localize a putative tumor suppressor gene to a region homologous with human chromosome 1p36. (Herzog CR, Wang Y, You M) Oncogene 1995 Nov 02;11(9):1811-5 PMID: 7478609 SCOPUS ID: 2-s2.0-0028824273 11/02/1995       39 Citations
  • K-ras mutations in lung tumors from A/J and A/J x TSG-p53 F1 mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothiocyanate. (Matzinger SA, Crist KA, Stoner GD, Anderson MW, Pereira MA, Steele VE, Kelloff GJ, Lubet RA, You M) Carcinogenesis 1995 Oct;16(10):2487-92 PMID: 7586156 SCOPUS ID: 2-s2.0-0028838588 10/01/1995       48 Citations
  • Allele-specific activation and expression of the K-ras gene in hybrid mouse lung tumors induced by chemical carcinogens. (Chen B, You L, Wang Y, Stoner GD, You M) Carcinogenesis 1994 Sep;15(9):2031-5 PMID: 7923598 SCOPUS ID: 2-s2.0-0028059022 09/01/1994       42 Citations
  • Ki-ras mutations in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-initiated and butylated hydroxytoluene-promoted lung tumors in A/J mice. (Matzinger SA, Gunning WT, You M, Castonguay A) Mol Carcinog 1994 Sep;11(1):42-8 PMID: 7916989 SCOPUS ID: 2-s2.0-0028152662 09/01/1994       22 Citations
  • Deletion mapping of a putative tumor suppressor gene on chromosome 4 in mouse lung tumors. (Herzog CR, Wiseman RW, You M) Cancer Res 1994 Aug 01;54(15):4007-10 PMID: 8033131 SCOPUS ID: 2-s2.0-0028001112 08/01/1994       60 Citations
  • The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility. (Chen B, Johanson L, Wiest JS, Anderson MW, You M) Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1589-93 PMID: 8108449 PMCID: PMC43205 SCOPUS ID: 2-s2.0-0027979481 02/15/1994       86 Citations
  • Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors. (Chen B, Liu L, Castonguay A, Maronpot RR, Anderson MW, You M) Carcinogenesis 1993 Aug;14(8):1603-8 PMID: 8353844 SCOPUS ID: 2-s2.0-0027292743 08/01/1993       99 Citations
  • Risk of miscarriage and a common variant of the estrogen receptor gene. (Taylor JA, Wilcox AJ, Bowes WA, Li Y, Liu ET, You M) Am J Epidemiol 1993 Jun 15;137(12):1361-4 PMID: 8333417 SCOPUS ID: 2-s2.0-0027320809 06/15/1993       21 Citations
  • K-ras mutations in benzotrichloride-induced lung tumors of A/J mice. (You M, Wang Y, Nash B, Stoner GD) Carcinogenesis 1993 Jun;14(6):1247-9 PMID: 8508514 SCOPUS ID: 2-s2.0-0027284740 06/01/1993       11 Citations
  • ras mutations in 2-acetylaminofluorene-induced lung and liver tumors from C3H/HeJ and (C3H x A/J)F1 mice. (Wang Y, Wang Y, Stoner G, You M) Cancer Res 1993 Apr 01;53(7):1620-4 PMID: 8453632 SCOPUS ID: 2-s2.0-0027521097 04/01/1993       22 Citations
  • ras mutations in 2-amino-3-methylimidazo-[4,5-f]quinoline-induced tumors in the CDF1 mouse. (Herzog CR, Schut HA, Maronpot RR, You M) Mol Carcinog 1993;8(3):202-7 PMID: 8216739 SCOPUS ID: 2-s2.0-0027332467 01/01/1993       10 Citations
  • Role of proto-oncogene activation in carcinogenesis. (Anderson MW, Reynolds SH, You M, Maronpot RM) Environ Health Perspect 1992 Nov;98:13-24 PMID: 1486840 PMCID: PMC1519627 SCOPUS ID: 2-s2.0-0027057548 11/01/1992       92 Citations
  • Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine. (You M, Wang Y, Lineen AM, Gunning WT, Stoner GD, Anderson MW) Carcinogenesis 1992 Sep;13(9):1583-6 PMID: 1394843 SCOPUS ID: 2-s2.0-0026644013 09/01/1992       51 Citations
  • Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids. (You M, Wang Y, Stoner G, You L, Maronpot R, Reynolds SH, Anderson M) Proc Natl Acad Sci U S A 1992 Jul 01;89(13):5804-8 PMID: 1352876 PMCID: PMC402106 SCOPUS ID: 2-s2.0-0026764662 07/01/1992       96 Citations
  • B region variant of the estrogen receptor gene. (Taylor JA, Li Y, You M, Wilcox AJ, Liu E) Nucleic Acids Res 1992 Jun 11;20(11):2895 PMID: 1614882 PMCID: PMC336947 SCOPUS ID: 2-s2.0-0026755658 06/11/1992       20 Citations
  • Protooncogene activation in spontaneously occurring and chemically induced rodent and human lung tumors. (Reynolds SH, Wiest JS, Devereux TR, Anderson MW, You M) Prog Clin Biol Res 1992;376:303-20 PMID: 1528924 SCOPUS ID: 2-s2.0-0026444417 01/01/1992       25 Citations
  • Activation of protooncogenes in mouse lung tumors. (You M, Wang Y, Lineen A, Stoner GD, You LA, Maronpot RR, Anderson MW) Exp Lung Res 1991 Mar-Apr;17(2):389-400 PMID: 2050038 SCOPUS ID: 2-s2.0-0026034579 03/01/1991       18 Citations
  • Activation of protooncogenes in spontaneously occurring non-liver tumors from C57BL/6 x C3H F1 mice. (Candrian U, You M, Goodrow T, Maronpot RR, Reynolds SH, Anderson MW) Cancer Res 1991 Feb 15;51(4):1148-53 PMID: 1997158 SCOPUS ID: 2-s2.0-0025728908 02/15/1991       31 Citations
  • Establishment and characterization of SV40 T-antigen immortalized human esophageal epithelial cells. (Stoner GD, Kaighn ME, Reddel RR, Resau JH, Bowman D, Naito Z, Matsukura N, You M, Galati AJ, Harris CC) Cancer Res 1991 Jan 01;51(1):365-71 PMID: 1703038 SCOPUS ID: 2-s2.0-0026079119 01/01/1991       143 Citations
  • Proto-oncogene activation in rodent and human tumors. (Anderson MW, You M, Reynolds SH) Adv Exp Med Biol 1991;283:235-43 PMID: 2068988 SCOPUS ID: 2-s2.0-0026069962 01/01/1991       3 Citations
  • Mutational activation of the cellular Harvey ras oncogene in rat esophageal papillomas induced by methylbenzylnitrosamine. (Wang Y, You M, Reynolds SH, Stoner GD, Anderson MW) Cancer Res 1990 Mar 01;50(5):1591-5 PMID: 2406014 SCOPUS ID: 2-s2.0-0025304093 03/01/1990       89 Citations
  • Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse. (You M, Candrian U, Maronpot RR, Stoner GD, Anderson MW) Proc Natl Acad Sci U S A 1989 May;86(9):3070-4 PMID: 2654935 PMCID: PMC287066 SCOPUS ID: 2-s2.0-0007142725 05/01/1989       336 Citations
  • Measurement of oxygen and carbon dioxide partial pressures in synovial fluid after tonometry. (Geborek P, Lindoff B, Valind SO) Clin Physiol 1988 Aug;8(4):427-32 PMID: 3136967 08/01/1988       5 Citations
  • Electrophysiology and dye-coupling are sexually dimorphic characteristics of individual laryngeal muscle fibers in Xenopus laevis. (Tobias ML, Kelley DB) J Neurosci 1988 Jul;8(7):2422-9 PMID: 3249234 PMCID: PMC3493212 07/01/1988       26 Citations
  • Lung tumor induction in strain A mice with benzotrichloride. (Stoner GD, You M, Morgan MA, Superczynski MJ) Cancer Lett 1986 Nov;33(2):167-73 PMID: 3791187 SCOPUS ID: 2-s2.0-0022995910 11/01/1986       5 Citations
  • Last update: 01/28/2020
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