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Medical College of Wisconsin

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Nathan A. Ledeboer PhD

Vice Chair, Professor

Institution: Medical College of Wisconsin
Department: Pathology
Division: Administration

I am willing to collaborate on research projects.
I am willing to mentor a junior faculty member.

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Publications (135)

Costs and Consequences of a Novel Emergency Department Sepsis Diagnostic Test: The IntelliSep Index. (Hollenbeak CS, Henning DJ, Geeting GK, Ledeboer NA, Faruqi IA, Pierce CG, Thomas CB, O'Neal HR Jr) Crit Care Explor 2023 Jul;5(7):e0942 PMID: 37465702 PMCID: PMC10351935 SCOPUS ID: 2-s2.0-85165590307 07/19/2023

Plasma Microbial Cell-Free DNA Sequencing from over 15,000 Patients Identified a Broad Spectrum of Pathogens. (Park SY, Chang EJ, Ledeboer N, Messacar K, Lindner MS, Venkatasubrahmanyam S, Wilber JC, Vaughn ML, Bercovici S, Perkins BA, Nolte FS) J Clin Microbiol 2023 Aug 23;61(8):e0185522 PMID: 37439686 PMCID: PMC10446866 SCOPUS ID: 2-s2.0-85168782097 07/13/2023 1 Citation

Rapid identification of sepsis in the emergency department. (Kraus CK, Nguyen HB, Jacobsen RC, Ledeboer NA, May LS, O'Neal HR Jr, Puskarich MA, Rice TW, Self WH, Rothman RE) J Am Coll Emerg Physicians Open 2023 Jun;4(3):e12984 PMID: 37284425 PMCID: PMC10239543 06/07/2023

A phase 2 trial of a topical antiseptic bundle in head and neck cancer surgery: Effects on surgical site infection and the oral microbiome. (Zenga J, Atkinson S, Yen T, Massey B, Stadler M, Bruening J, Peppard W, Reuben M, Hayward M, Mesich B, Buchan B, Ledeboer N, Sanchez JL, Fraser R, Lin CW, Holtz ML, Awan M, Wong SJ, Puram SV, Salzman N) EBioMedicine 2022 Jul;81:104099 PMID: 35671624 PMCID: PMC9168040 SCOPUS ID: 2-s2.0-85131428877 06/08/2022

Erratum for Pancholi et al., "Multicenter Evaluation of the Simplexa VZV Direct Assay for Detection of Varicella-Zoster Virus in Cerebrospinal Fluid and Lesion-Swab Specimens". (Pancholi P, Relich RF, Chandrasekaran S, Dunn JJ, Granato PA, Harrington AT, Hansen GT, Ledeboer NA, Li Q, Sims MD, Uphoff TS, Greene W, Young S, Dhiman N) J Clin Microbiol 2022 May 18;60(5):e0052722 PMID: 35465725 PMCID: PMC9116167 SCOPUS ID: 2-s2.0-85130765793 04/26/2022

Multicenter Evaluation of the Simplexa VZV Direct Assay for Detection of Varicella-Zoster Virus in Cerebrospinal Fluid and Lesion-Swab Specimens. (Pancholi P, Relich RF, Chandrasekaran S, Dunn JJ, Granato PA, Harrington AT, Hansen GT, Ledeboer NA, Li Q, Sims MD, Uphoff TS, Greene W, Young S, Dhiman N) J Clin Microbiol 2022 Apr 20;60(4):e0235521 PMID: 35285727 PMCID: PMC9020333 SCOPUS ID: 2-s2.0-85128801876 03/15/2022 1 Citation

Efficacy of a third SARS-CoV-2 mRNA vaccine dose among hematopoietic cell transplantation, CAR T cell, and BiTE recipients. (Abid MB, Rubin M, Ledeboer N, Szabo A, Longo W, Mohan M, Shah NN, Fenske TS, Abedin S, Runaas L, D'Souza A, Chhabra S, Dhakal B, Hamadani M) Cancer Cell 2022 Apr 11;40(4):340-342 PMID: 35202585 PMCID: PMC8864440 SCOPUS ID: 2-s2.0-85127542763 02/25/2022 24 Citations

SARS-CoV-2 Cycle Thresholds, Poverty, Race, and Clinical Outcomes. (Rivera F, Gmehlin CG, Pezzin LE, Hanson R, Perez A, Singh S, Ledeboer NA, Buchan BW, Nattinger AB, Munoz-Price LS) WMJ 2021 Dec;120(4):301-304 PMID: 35025178 SCOPUS ID: 2-s2.0-85123460891 01/14/2022

Comparison of Methods for Determining the Antibiotic Susceptibility of Aerococcus Species in a Clinical Setting. (Scholtz SL, Faron ML, Buchan BW, Ledeboer NA) Am J Clin Pathol 2022 May 04;157(5):781-788 PMID: 34893797 SCOPUS ID: 2-s2.0-85129998230 12/12/2021 1 Citation

Cytotoxic CD8-positive T-lymphocyte infiltration in the lungs as a histological pattern of SARS-CoV-2 pneumonitis. (Puzyrenko A, Felix JC, Ledeboer NA, Sun Y, Rui H, Sheinin Y) Pathology 2022 Jun;54(4):404-408 PMID: 34836647 PMCID: PMC8572726 SCOPUS ID: 2-s2.0-85119915379 11/28/2021 2 Citations

Point-of-care COVID-19 testing in the emergency department: current status and future prospects. (May L, Tran N, Ledeboer NA) Expert Rev Mol Diagn 2021 Dec;21(12):1333-1340 PMID: 34758686 PMCID: PMC8631689 SCOPUS ID: 2-s2.0-85120077883 11/12/2021 9 Citations

Rapid identification from rectal swabs of the clinically most relevant carbapenemase genes from gram-negative bacteria using the BD MAX Check-Points CPO Assay. (García-Fernández S, Simner PJ, Thomson G, Faron M, Bosboom R, van Griethuijsen A, García-Castillo M, Harris R, Ledeboer NA, Cantón R, Thomson KS) Diagn Microbiol Infect Dis 2022 Jan;102(1):115554 PMID: 34678712 SCOPUS ID: 2-s2.0-85117421272 10/23/2021 1 Citation

Response to SARS-CoV-2 vaccination in patients after hematopoietic cell transplantation and CAR T-cell therapy. (Dhakal B, Abedin S, Fenske T, Chhabra S, Ledeboer N, Hari P, Hamadani M) Blood 2021 Oct 07;138(14):1278-1281 PMID: 34339501 PMCID: PMC8332674 SCOPUS ID: 2-s2.0-85114112109 08/03/2021 80 Citations

A Novel Multiplexed Enzyme-Linked Immunosorbent Assay for the Detection of IgG Seroreactivity to Cytomegalovirus (CMV) UL144. (Miller H, Simpson P, Forman M, Prigan A, Kehl S, Mesich B, Faron M, Ledeboer N, Arav-Boger R) J Clin Microbiol 2021 Jul 19;59(8):e0096421 PMID: 34076473 PMCID: PMC8373222 SCOPUS ID: 2-s2.0-85112127278 06/03/2021

Surveillance cultures following a regional outbreak of carbapenem-resistant Acinetobacter baumannii. (Rivera F, Reeme A, Graham MB, Buchan BW, Ledeboer NA, Valley AM, Munoz-Price LS) Infect Control Hosp Epidemiol 2022 Apr;43(4):454-460 PMID: 33985611 SCOPUS ID: 2-s2.0-85105848855 05/15/2021 1 Citation

Evaluation of a High-Definition PCR Assay for the Detection of SARS-CoV-2 in Extracted and Nonextracted Respiratory Specimens Collected in Various Transport Media. (Buchan BW, Gerstbrein D, Cruz A, Hoff J, Sievert E, Ledeboer NA, Faron ML) Am J Clin Pathol 2021 Jun 17;156(1):24-33 PMID: 33940605 PMCID: PMC8135719 SCOPUS ID: 2-s2.0-85108387082 05/04/2021

Can a Clean Catch Urine Sample Be Used to Diagnose Chlamydia and Gonorrhea in Adolescent Females? (Pickett ML, Visotcky A, Brazauskas R, Ledeboer NA, Drendel AL) J Adolesc Health 2021 Oct;69(4):574-578 PMID: 33846057 SCOPUS ID: 2-s2.0-85104082927 04/14/2021 2 Citations

Air contamination of households versus hospital inpatient rooms occupied by severe acute respiratory coronavirus virus 2 (SARS-CoV-2)-positive patients. (Munoz-Price LS, Rivera F, Ledeboer N) Infect Control Hosp Epidemiol 2022 Feb;43(2):248-252 PMID: 33536089 PMCID: PMC8047394 SCOPUS ID: 2-s2.0-85124850576 02/05/2021 4 Citations

Decrease in Positivity Rate of Influenza Tests Coinciding With Outbreak of SARS-CoV-2: Data From a Southeastern Wisconsin Laboratory. (Singh S, Ledeboer NA, Laud PW, Hanson R, Truwit JD) WMJ 2020 Dec;119(4):275-277 PMID: 33428839 SCOPUS ID: 2-s2.0-85099899804 01/12/2021 3 Citations

Point-of-care COVID-19 testing in the emergency department: current status and future prospects (May L, Tran N, Ledeboer NA) Expert Review of Molecular Diagnostics 2021;21(12):1333-1340 SCOPUS ID: 2-s2.0-85120077883 01/01/2021 9 Citations

A Multi-mRNA Host-Response Molecular Blood Test for the Diagnosis and Prognosis of Acute Infections and Sepsis: Proceedings from a Clinical Advisory Panel. (Ducharme J, Self WH, Osborn TM, Ledeboer NA, Romanowsky J, Sweeney TE, Liesenfeld O, Rothman RE) J Pers Med 2020 Dec 07;10(4) PMID: 33297498 PMCID: PMC7762405 SCOPUS ID: 2-s2.0-85097744621 12/11/2020 22 Citations

Digital Image Analysis for the Detection of Group B Streptococcus from ChromID Strepto B Medium Using PhenoMatrix Algorithms. (Baker J, Timm K, Faron M, Ledeboer N, Culbreath K) J Clin Microbiol 2020 Dec 17;59(1) PMID: 33087433 PMCID: PMC7771474 SCOPUS ID: 2-s2.0-85098517412 10/23/2020 5 Citations

Racial Disparities in Incidence and Outcomes Among Patients With COVID-19. (Muñoz-Price LS, Nattinger AB, Rivera F, Hanson R, Gmehlin CG, Perez A, Singh S, Buchan BW, Ledeboer NA, Pezzin LE) JAMA Netw Open 2020 Sep 01;3(9):e2021892 PMID: 32975575 PMCID: PMC7519420 SCOPUS ID: 2-s2.0-85091807867 09/26/2020 233 Citations

Impact of an Antimicrobial Stewardship Program Pharmacist During Microbiology Rounds. (Sapozhnikov J, Huang A, Revolinski S, Ledeboer NA, Buchan BW) Am J Clin Pathol 2021 Feb 11;155(3):455-460 PMID: 32949141 SCOPUS ID: 2-s2.0-85102099001 09/20/2020 3 Citations

Toxigenic Clostridioides difficile colonization as a risk factor for development of C. difficile infection in solid-organ transplant patients. (Keegan J, Buchan BW, Ledeboer NA, Zhou Z, Hong JC, Graham MB, Munoz-Price LS) Infect Control Hosp Epidemiol 2021 Mar;42(3):287-291 PMID: 32933595 SCOPUS ID: 2-s2.0-85092160301 09/17/2020 1 Citation

Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Asymptomatic Infections in 2 Large Academic Health Systems in Wisconsin. (Rivera F, Safdar N, Ledeboer N, Schaack G, Chen DJ, Munoz-Price LS) Clin Infect Dis 2021 Dec 06;73(11):e3974-e3976 PMID: 32812030 PMCID: PMC7454339 SCOPUS ID: 2-s2.0-85122546930 08/20/2020 2 Citations

Direct detection of intact Klebsiella pneumoniae carbapenemase variants from cell lysates: Identification, characterization and clinical implications (McGee WM, Faron ML, Neil JR, Kronewitter SR, Buchan BW, Ledeboer NA, Stephenson JL) Clinical Mass Spectrometry August 2020;17:12-21 SCOPUS ID: 2-s2.0-85089093667 08/01/2020 3 Citations

Distribution of SARS-CoV-2 PCR Cycle Threshold Values Provide Practical Insight Into Overall and Target-Specific Sensitivity Among Symptomatic Patients. (Buchan BW, Hoff JS, Gmehlin CG, Perez A, Faron ML, Munoz-Price LS, Ledeboer NA) Am J Clin Pathol 2020 Sep 08;154(4):479-485 PMID: 32687186 PMCID: PMC7454307 SCOPUS ID: 2-s2.0-85091263722 07/21/2020 47 Citations

Direct detection of intact Klebsiella pneumoniae carbapenemase variants from cell lysates: Identification, characterization and clinical implications. (McGee WM, Faron ML, Neil JR, Kronewitter SR, Buchan BW, Ledeboer NA, Stephenson JL Jr) Clin Mass Spectrom 2020 Aug;17:12-21 PMID: 34820520 PMCID: PMC8600995 SCOPUS ID: 2-s2.0-85089093667 07/18/2020 3 Citations

Evaluation of NG-Test Carba 5 for Rapid Phenotypic Detection and Differentiation of Five Common Carbapenemase Families: Results of a Multicenter Clinical Evaluation. (Jenkins S, Ledeboer NA, Westblade LF, Burnham CA, Faron ML, Bergman Y, Yee R, Mesich B, Gerstbrein D, Wallace MA, Robertson A, Fauntleroy KA, Klavins AS, Malherbe R, Hsiung A, Simner PJ) J Clin Microbiol 2020 Jun 24;58(7) PMID: 32376668 PMCID: PMC7315033 SCOPUS ID: 2-s2.0-85086924996 05/08/2020 23 Citations

Achromobacter xylosoxidans Cellular Pathology Is Correlated with Activation of a Type III Secretion System. (Pickrum AM, DeLeon O, Dirck A, Tessmer MH, Riegert MO, Biller JA, Ledeboer NA, Kirby JR, Frank DW) Infect Immun 2020 Jun 22;88(7) PMID: 32366575 PMCID: PMC7309624 SCOPUS ID: 2-s2.0-85088536617 05/06/2020 14 Citations

Practical Comparison of the BioFire FilmArray Pneumonia Panel to Routine Diagnostic Methods and Potential Impact on Antimicrobial Stewardship in Adult Hospitalized Patients with Lower Respiratory Tract Infections. (Buchan BW, Windham S, Balada-Llasat JM, Leber A, Harrington A, Relich R, Murphy C, Dien Bard J, Naccache S, Ronen S, Hopp A, Mahmutoglu D, Faron ML, Ledeboer NA, Carroll A, Stone H, Akerele O, Everhart K, Bonwit A, Kwong C, Buckner R, Warren D, Fowler R, Chandrasekaran S, Huse H, Campeau S, Humphries R, Graue C, Huang A) J Clin Microbiol 2020 Jun 24;58(7) PMID: 32350045 PMCID: PMC7315039 SCOPUS ID: 2-s2.0-85086931042 05/01/2020 88 Citations

Multicenter Clinical Evaluation of the Revogene Strep A Molecular Assay for Detection of Streptococcus pyogenes from Throat Swab Specimens. (Banerjee D, Michael J, Schmitt B, Salimnia H, Mhaissen N, Goldfarb DM, Lachance P, Faron ML, Aufderheide T, Ledeboer N, Weissfeld A, Selvarangan R) J Clin Microbiol 2020 Jun 24;58(7) PMID: 32321780 PMCID: PMC7315036 SCOPUS ID: 2-s2.0-85086930057 04/24/2020 5 Citations

Evaluation of the WASPLab Segregation Software To Automatically Analyze Urine Cultures Using Routine Blood and MacConkey Agars. (Faron ML, Buchan BW, Relich RF, Clark J, Ledeboer NA) J Clin Microbiol 2020 Mar 25;58(4) PMID: 31941690 PMCID: PMC7098764 SCOPUS ID: 2-s2.0-85082542587 01/17/2020 13 Citations

Association Between Environmental Factors and Toxigenic Clostridioides difficile Carriage at Hospital Admission. (Muñoz-Price LS, Hanson R, Singh S, Nattinger AB, Penlesky A, Buchan BW, Ledeboer NA, Beyer K, Namin S, Zhou Y, Pezzin LE) JAMA Netw Open 2020 Jan 03;3(1):e1919132 PMID: 31922563 PMCID: PMC6991319 SCOPUS ID: 2-s2.0-85077730785 01/11/2020 6 Citations

A Multicenter Study of the Revogene C. difficile System for Detection of the Toxin B Gene from Unformed Stool Specimens. (Mashock MJ, Faron ML, Carroll KC, Dang C, Lewis S, Salimnia H, Lephart P, Loo VG, Schmitt BH, Young S, Buchan BW, Ledeboer NA) J Clin Microbiol 2020 Jan 28;58(2) PMID: 31776191 PMCID: PMC6989061 SCOPUS ID: 2-s2.0-85078685786 11/30/2019 2 Citations

Evaluation of WASPLab Software To Automatically Read chromID CPS Elite Agar for Reporting of Urine Cultures. (Faron ML, Buchan BW, Samra H, Ledeboer NA) J Clin Microbiol 2019 Dec 23;58(1) PMID: 31694967 PMCID: PMC6935927 SCOPUS ID: 2-s2.0-85077223772 11/07/2019 15 Citations

Multicenter Study Demonstrates Standardization Requirements for Mold Identification by MALDI-TOF MS. (Lau AF, Walchak RC, Miller HB, Slechta ES, Kamboj K, Riebe K, Robertson AE, Gilbreath JJ, Mitchell KF, Wallace MA, Bryson AL, Balada-Llasat JM, Bulman A, Buchan BW, Burnham CD, Butler-Wu S, Desai U, Doern CD, Hanson KE, Henderson CM, Kostrzewa M, Ledeboer NA, Maier T, Pancholi P, Schuetz AN, Shi G, Wengenack NL, Zhang SX, Zelazny AM, Frank KM) Front Microbiol 2019;10:2098 PMID: 31616388 PMCID: PMC6764242 SCOPUS ID: 2-s2.0-85072975776 10/17/2019 32 Citations

Evaluation of a Novel Multiplex High-Definition PCR Assay for Detection of Tick-Borne Pathogens in Whole-Blood Specimens. (Buchan BW, Jobe DA, Mashock M, Gerstbrein D, Faron ML, Ledeboer NA, Callister SM) J Clin Microbiol 2019 Nov;57(11) PMID: 31484700 PMCID: PMC6812998 SCOPUS ID: 2-s2.0-85074119071 09/06/2019 18 Citations

Use of a cohorting-unit and systematic surveillance cultures to control a Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae outbreak. (Reeme AE, Bowler SL, Buchan BW, Graham MB, Behrens E, Singh S, Hong JC, Arvan J, Hyke JW, Palen L, Savage S, Seliger H, Huerta S, Ledeboer NA, Kotay S, Mathers AJ, Cooper VS, Mustapha MM, Mettus RT, Doi Y, Munoz-Price LS) Infect Control Hosp Epidemiol 2019 Jul;40(7):767-773 PMID: 31084655 SCOPUS ID: 2-s2.0-85065637314 05/16/2019 5 Citations

Diagnosing and Managing Sepsis by Probing the Host Response to Infection: Advances, Opportunities, and Challenges. (Gunsolus IL, Sweeney TE, Liesenfeld O, Ledeboer NA) J Clin Microbiol 2019 Jul;57(7) PMID: 31043466 PMCID: PMC6595443 SCOPUS ID: 2-s2.0-85068514285 05/03/2019 25 Citations

Clinical Microbiology Is Growing Up: The Total Laboratory Automation Revolution. (Bailey AL, Ledeboer N, Burnham CD) Clin Chem 2019 May;65(5):634-643 PMID: 30518664 SCOPUS ID: 2-s2.0-85065503043 12/07/2018 38 Citations

Immediate impact of healthcare-facility-onset Clostridium difficile laboratory-identified events reporting methodology change on standardized infection ratios. (Figueroa Castro CE, Palen L, Johnson C, Graham MB, Letzer D, Ledeboer N, Buchan B, Block T, Seliger H, Singh S, Behrens E, Huerta S, Munoz-Price LS) Infect Control Hosp Epidemiol 2018 Dec;39(12):1484-1486 PMID: 30348236 SCOPUS ID: 2-s2.0-85055537816 10/24/2018 1 Citation

The relevance of sink proximity to toilets on the detection of Klebsiella pneumoniae carbapenemase inside sink drains. (Buchan BW, Graham MB, Lindmair-Snell J, Arvan J, Ledeboer NA, Nanchal R, Munoz-Price LS) Am J Infect Control 2019 Jan;47(1):98-100 PMID: 30172608 SCOPUS ID: 2-s2.0-85052737901 09/03/2018 15 Citations

Multicenter evaluation of the Alere™ i influenza A&B assay using respiratory specimens collected in viral transport media. (Hassan F, Crawford J, Bonner AB, Ledeboer NA, Selvarangan R) Diagn Microbiol Infect Dis 2018 Dec;92(4):294-298 PMID: 30077505 SCOPUS ID: 2-s2.0-85050811176 08/06/2018 9 Citations

Clinical Evaluation of the iCubate iC-GPC Assay for Detection of Gram-Positive Bacteria and Resistance Markers from Positive Blood Cultures. (Granato PA, Unz MM, Widen RH, Silbert S, Young S, Heflin KL, Conover MS, Buchan BW, Ledeboer NA) J Clin Microbiol 2018 Sep;56(9) PMID: 29899000 PMCID: PMC6113461 SCOPUS ID: 2-s2.0-85052491577 06/15/2018 8 Citations

Elizabethkingia anophelis: Clinical Experience of an Academic Health System in Southeastern Wisconsin. (Figueroa Castro CE, Johnson C, Williams M, VanDerSlik A, Graham MB, Letzer D, Ledeboer N, Buchan BW, Block T, Borlaug G, Munoz-Price LS) Open Forum Infect Dis 2017;4(4):ofx251 PMID: 29308406 PMCID: PMC5751080 SCOPUS ID: 2-s2.0-85056804311 01/09/2018 23 Citations

Multicenter Evaluation of the Accelerate PhenoTest BC Kit for Rapid Identification and Phenotypic Antimicrobial Susceptibility Testing Using Morphokinetic Cellular Analysis. (Pancholi P, Carroll KC, Buchan BW, Chan RC, Dhiman N, Ford B, Granato PA, Harrington AT, Hernandez DR, Humphries RM, Jindra MR, Ledeboer NA, Miller SA, Mochon AB, Morgan MA, Patel R, Schreckenberger PC, Stamper PD, Simner PJ, Tucci NE, Zimmerman C, Wolk DM) J Clin Microbiol 2018 Apr;56(4) PMID: 29305546 PMCID: PMC5869823 SCOPUS ID: 2-s2.0-85044779516 01/07/2018 120 Citations

Effective utilization of C. difficile PCR and identification of clinicopathologic factors associated with conversion to a positive result in symptomatic patients. (Mostafa ME, Flynn T, Hartley CP, Ledeboer NA, Buchan BW) Diagn Microbiol Infect Dis 2018 Apr;90(4):307-310 PMID: 29290473 SCOPUS ID: 2-s2.0-85039550113 01/02/2018 1 Citation

Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Use with Positive Blood Cultures: Methodology, Performance, and Optimization. (Faron ML, Buchan BW, Ledeboer NA) J Clin Microbiol 2017 Dec;55(12):3328-3338 PMID: 28855303 PMCID: PMC5703799 SCOPUS ID: 2-s2.0-85036667185 09/01/2017 67 Citations

Evaluation of Copan FecalSwab as Specimen Type for Use in Xpert C. difficile Assay. (Mashock MJ, Faron ML, Buchan BW, Ledeboer NA) J Clin Microbiol 2017 Oct;55(10):3123-3129 PMID: 28794179 PMCID: PMC5625397 SCOPUS ID: 2-s2.0-85030127876 08/11/2017 8 Citations

Processing Positive Cultures (Faron ML, Ledeboer NA) Dark Art of Blood Cultures 1 August 2017:207-244 SCOPUS ID: 2-s2.0-85102228066 08/01/2017

A Novel Protocol Obviates Endoscope Sampling for Carbapenem-Resistant Enterobacteriaceae: Experience of a Center with a Prior Outbreak. (Smith ZL, Dua A, Saeian K, Ledeboer NA, Graham MB, Aburajab M, Ballard DD, Khan AH, Dua KS) Dig Dis Sci 2017 Nov;62(11):3100-3109 PMID: 28681083 SCOPUS ID: 2-s2.0-85021843628 07/07/2017 10 Citations

Impact of Organism Identification Method on Central Line-Associated Bloodstream Infection Designation. (Gomez EJ, Roberts AL, Robinson DP, Alby K, Ledeboer NA, Doern CD, Lander DW, Bearman G, Sullivan KV) Infect Control Hosp Epidemiol 2017 Aug;38(8):1007-1009 PMID: 28633680 SCOPUS ID: 2-s2.0-85021144054 06/22/2017

Multicenter Evaluation of the Bruker MALDI Biotyper CA System for the Identification of Clinically Important Bacteria and Yeasts. (Wilson DA, Young S, Timm K, Novak-Weekley S, Marlowe EM, Madisen N, Lillie JL, Ledeboer NA, Smith R, Hyke J, Griego-Fullbright C, Jim P, Granato PA, Faron ML, Cumpio J, Buchan BW, Procop GW) Am J Clin Pathol 2017 Jun 01;147(6):623-631 PMID: 28505220 SCOPUS ID: 2-s2.0-85031705467 05/16/2017 19 Citations

Multicenter Evaluation of the Portrait Staph ID/R Blood Culture Panel for Rapid Identification of Staphylococci and Detection of the mecA Gene. (Denys GA, Collazo-Velez V, Young S, Daly JA, Couturier MR, Faron ML, Buchan BW, Ledeboer N) J Clin Microbiol 2017 Apr;55(4):1140-1146 PMID: 28122871 PMCID: PMC5377841 SCOPUS ID: 2-s2.0-85016173124 01/27/2017 3 Citations

Clinical Evaluation and Cost Analysis of Great Basin Shiga Toxin Direct Molecular Assay for Detection of Shiga Toxin-Producing Escherichia coli in Diarrheal Stool Specimens. (Faron ML, Ledeboer NA, Connolly J, Granato PA, Alkins BR, Dien Bard J, Daly JA, Young S, Buchan BW) J Clin Microbiol 2017 Feb;55(2):519-525 PMID: 27927919 PMCID: PMC5277522 SCOPUS ID: 2-s2.0-85011977894 12/09/2016 5 Citations

Antimicrobial Curtains: Are They as Clean as You Think? (Sridhar SA, Ledeboer NA, Nanchal RS, Mackey T, Graham MB, VanDerSlik A, Silvia Munoz-Price L) Infect Control Hosp Epidemiol 2016 Oct;37(10):1260-2 PMID: 27530468 SCOPUS ID: 2-s2.0-84988807834 08/18/2016

Automatic Digital Analysis of Chromogenic Media for Vancomycin-Resistant-Enterococcus Screens Using Copan WASPLab. (Faron ML, Buchan BW, Coon C, Liebregts T, van Bree A, Jansz AR, Soucy G, Korver J, Ledeboer NA) J Clin Microbiol 2016 Oct;54(10):2464-9 PMID: 27413193 PMCID: PMC5035414 SCOPUS ID: 2-s2.0-84991216241 07/15/2016 32 Citations

Multicenter Evaluation of the Solana Group A Streptococcus Assay: Comparison with Culture. (Uphoff TS, Buchan BW, Ledeboer NA, Granato PA, Daly JA, Marti TN) J Clin Microbiol 2016 Sep;54(9):2388-90 PMID: 27358464 PMCID: PMC5005512 SCOPUS ID: 2-s2.0-84983593764 07/01/2016 13 Citations

Automation advances microbiology to operational excellence. (Ledeboer NA) MLO Med Lab Obs 2016 May;48(5):8-11; quiz 12 PMID: 27323451 SCOPUS ID: 2-s2.0-84979098390 06/22/2016 1 Citation

Multicenter Evaluation of Meridian Bioscience HSV 1&2 Molecular Assay for Detection of Herpes Simplex Virus 1 and 2 from Clinical Cutaneous and Mucocutaneous Specimens. (Faron ML, Ledeboer NA, Patel A, Beqa SH, Yen-Lieberman B, Kohn D, Leber AL, Mayne D, Northern WI, Buchan BW) J Clin Microbiol 2016 Aug;54(8):2008-13 PMID: 27194690 PMCID: PMC4963491 SCOPUS ID: 2-s2.0-84979502519 05/20/2016 8 Citations

Resistance Mechanisms, Epidemiology, and Approaches to Screening for Vancomycin-Resistant Enterococcus in the Health Care Setting. (Faron ML, Ledeboer NA, Buchan BW) J Clin Microbiol 2016 Oct;54(10):2436-47 PMID: 27147728 PMCID: PMC5035425 SCOPUS ID: 2-s2.0-84991208719 05/06/2016 132 Citations

Comparison of ESwab and Wound Fiber Swab Specimen Collection Devices for Use with Xpert SA Nasal Complete Assay. (Beck ET, Buchan BW, Reymann GC, Ledeboer NA) J Clin Microbiol 2016 Jul;54(7):1904-1906 PMID: 27122376 PMCID: PMC4922099 SCOPUS ID: 2-s2.0-84976345917 04/29/2016 5 Citations

Mycobacterium mucogenicum bacteremia in immune-compromised patients, 2008-2013. (Abidi MZ, Ledeboer N, Banerjee A, Hari P) Diagn Microbiol Infect Dis 2016 Jun;85(2):182-5 PMID: 27117516 SCOPUS ID: 2-s2.0-84964211718 04/28/2016 7 Citations

Reducing the risk of nosocomial dissemination of methicillin-resistant staphylococcus aureus: An infection control perspective (Edmiston CE, Ledeboer NA) MRSA: Second Edition 19 April 2016:204-231 SCOPUS ID: 2-s2.0-85052168025 04/19/2016

Morbidity and mortality attributable to Rothia bacteremia in neutropenic and nonneutropenic patients. (Abidi MZ, Ledeboer N, Banerjee A, Hari P) Diagn Microbiol Infect Dis 2016 May;85(1):116-20 PMID: 26906191 SCOPUS ID: 2-s2.0-84959066272 02/26/2016 20 Citations

Is Staphylococcal Screening and Suppression an Effective Interventional Strategy for Reduction of Surgical Site Infection? (Edmiston CE Jr, Ledeboer NA, Buchan BW, Spencer M, Seabrook GR, Leaper D) Surg Infect (Larchmt) 2016 Apr;17(2):158-66 PMID: 26836053 SCOPUS ID: 2-s2.0-84962549354 02/03/2016 16 Citations

Verification and validation of matrix-assisted laser desorption ionization time of flight mass spectrometry-based protocols (Faron ML, Buchan BW, Ledeboer NA) Molecular Microbiology: Diagnostic Principles and Practice 27 January 2016:784-796 SCOPUS ID: 2-s2.0-85102324545 01/27/2016

Automated Scoring of Chromogenic Media for Detection of Methicillin-Resistant Staphylococcus aureus by Use of WASPLab Image Analysis Software. (Faron ML, Buchan BW, Vismara C, Lacchini C, Bielli A, Gesu G, Liebregts T, van Bree A, Jansz A, Soucy G, Korver J, Ledeboer NA) J Clin Microbiol 2016 Mar;54(3):620-4 PMID: 26719443 PMCID: PMC4767952 SCOPUS ID: 2-s2.0-84959505663 01/01/2016 43 Citations

The clinical and economic value of flexible diagnostic panels for respiratory pathogen testing. (Ledeboer N) MLO Med Lab Obs 2015 Nov;47(11):8, 10 PMID: 26685419 SCOPUS ID: 2-s2.0-85006306804 12/22/2015

Making the Leap from Research Laboratory to Clinic: Challenges and Opportunities for Next-Generation Sequencing in Infectious Disease Diagnostics. (Goldberg B, Sichtig H, Geyer C, Ledeboer N, Weinstock GM) mBio 2015 Dec 08;6(6):e01888-15 PMID: 26646014 PMCID: PMC4669390 SCOPUS ID: 2-s2.0-84952836879 12/10/2015 214 Citations

Multicenter Evaluation of MRSASelect II Chromogenic Agar for Identification of Methicillin-Resistant Staphylococcus aureus from Wound and Nasal Specimens. (Hernandez DR, Newton DW, Ledeboer NA, Buchan B, Young C, Clark AE, Connoly J, Wolk DM) J Clin Microbiol 2016 Feb;54(2):305-11 PMID: 26582836 PMCID: PMC4733205 SCOPUS ID: 2-s2.0-84956690099 11/20/2015 10 Citations

Multicenter Evaluation of the Xpert Norovirus Assay for Detection of Norovirus Genogroups I and II in Fecal Specimens. (Gonzalez MD, Langley LC, Buchan BW, Faron ML, Maier M, Templeton K, Walker K, Popowitch EB, Miller MB, Rao A, Liebert UG, Ledeboer NA, Vinjé J, Burnham CA) J Clin Microbiol 2016 Jan;54(1):142-7 PMID: 26560532 PMCID: PMC4702714 SCOPUS ID: 2-s2.0-84954319782 11/13/2015 33 Citations

Multicenter Evaluation of the Bruker MALDI Biotyper CA System for the Identification of Clinical Aerobic Gram-Negative Bacterial Isolates. (Faron ML, Buchan BW, Hyke J, Madisen N, Lillie JL, Granato PA, Wilson DA, Procop GW, Novak-Weekley S, Marlowe E, Cumpio J, Griego-Fullbright C, Kindig S, Timm K, Young S, Ledeboer NA) PLoS One 2015;10(11):e0141350 PMID: 26529504 PMCID: PMC4631355 SCOPUS ID: 2-s2.0-84951851740 11/04/2015 26 Citations

Comparative Evaluation of AmpliVue HSV 1+2 Assay with ELVIS Culture for Detecting Herpes Simplex Virus 1 (HSV-1) and HSV-2 in Clinical Specimens. (Granato PA, Alkins BR, Yen-Lieberman B, Greene WH, Connolly J, Buchan BW, Ledeboer NA) J Clin Microbiol 2015 Dec;53(12):3922-5 PMID: 26468497 PMCID: PMC4652092 SCOPUS ID: 2-s2.0-84947764664 10/16/2015 15 Citations

Identification of Gram-Negative Bacteria and Genetic Resistance Determinants from Positive Blood Culture Broths by Use of the Verigene Gram-Negative Blood Culture Multiplex Microarray-Based Molecular Assay. (Ledeboer NA, Lopansri BK, Dhiman N, Cavagnolo R, Carroll KC, Granato P, Thomson R Jr, Butler-Wu SM, Berger H, Samuel L, Pancholi P, Swyers L, Hansen GT, Tran NK, Polage CR, Thomson KS, Hanson ND, Winegar R, Buchan BW) J Clin Microbiol 2015 Aug;53(8):2460-72 PMID: 25994165 PMCID: PMC4508435 SCOPUS ID: 2-s2.0-84938118582 05/23/2015 110 Citations

CYP2C19*17 genetic polymorphism--an uncommon cause of voriconazole treatment failure. (Abidi MZ, D'Souza A, Kuppalli K, Ledeboer N, Hari P) Diagn Microbiol Infect Dis 2015 Sep;83(1):46-8 PMID: 25986028 SCOPUS ID: 2-s2.0-84938739008 05/20/2015 8 Citations

Detection of multi-drug resistant Escherichia coli in the urban waterways of Milwaukee, WI. (Kappell AD, DeNies MS, Ahuja NH, Ledeboer NA, Newton RJ, Hristova KR) Front Microbiol 2015;6:336 PMID: 25972844 PMCID: PMC4413672 SCOPUS ID: 2-s2.0-84930937287 05/15/2015 29 Citations

Detection of Group A Streptococcus in Pharyngeal Swab Specimens by Use of the AmpliVue GAS Isothermal Helicase-Dependent Amplification Assay. (Faron ML, Ledeboer NA, Granato P, Daly JA, Pierce K, Pancholi P, Uphoff TS, Buchan BW) J Clin Microbiol 2015 Jul;53(7):2365-7 PMID: 25972419 PMCID: PMC4473221 SCOPUS ID: 2-s2.0-84932620912 05/15/2015 10 Citations

Comparison of the next-generation Xpert MRSA/SA BC assay and the GeneOhm StaphSR assay to routine culture for identification of Staphylococcus aureus and methicillin-resistant S. aureus in positive-blood-culture broths. (Buchan BW, Allen S, Burnham CA, McElvania TeKippe E, Davis T, Levi M, Mayne D, Pancholi P, Relich RF, Thomson R, Ledeboer NA) J Clin Microbiol 2015 Mar;53(3):804-9 PMID: 25540397 PMCID: PMC4390651 SCOPUS ID: 2-s2.0-84923351710 12/30/2014 57 Citations

Implementation of Polymerase Chain Reaction to Rule Out Clostridium difficile Infection Is Associated With Reduced Empiric Antibiotic Duration of Therapy. (Peppard WJ, Ledeboer NA) Hosp Pharm 2014 Jul;49(7):639-43 PMID: 25477583 PMCID: PMC4252234 SCOPUS ID: 2-s2.0-84905395475 12/06/2014 8 Citations

Multicenter clinical evaluation of the Xpert GBS LB assay for detection of group B Streptococcus in prenatal screening specimens. (Buchan BW, Faron ML, Fuller D, Davis TE, Mayne D, Ledeboer NA) J Clin Microbiol 2015 Feb;53(2):443-8 PMID: 25411176 PMCID: PMC4298547 SCOPUS ID: 2-s2.0-84921778191 11/21/2014 30 Citations

Emerging technologies for the clinical microbiology laboratory. (Buchan BW, Ledeboer NA) Clin Microbiol Rev 2014 Oct;27(4):783-822 PMID: 25278575 PMCID: PMC4187641 SCOPUS ID: 2-s2.0-84907798849 10/04/2014 195 Citations

Antimicrobial activity of ceftaroline and other anti-infective agents against microbial pathogens recovered from the surgical intensive care patient population: a prevalence analysis. (Edmiston CE Jr, Krepel CJ, Leaper D, Ledeboer NA, Mackey TL, Graham MB, Lee C, Rossi PJ, Brown KR, Lewis BD, Seabrook GR) Surg Infect (Larchmt) 2014 Dec;15(6):745-51 PMID: 24896013 SCOPUS ID: 2-s2.0-84918531327 06/05/2014 3 Citations

Multicenter evaluation of the Quidel Lyra Direct C. difficile nucleic acid amplification assay. (Beck ET, Buchan BW, Riebe KM, Alkins BR, Pancholi P, Granato PA, Ledeboer NA) J Clin Microbiol 2014 Jun;52(6):1998-2002 PMID: 24671790 PMCID: PMC4042815 SCOPUS ID: 2-s2.0-84901650235 03/29/2014 13 Citations

The automated clinical microbiology laboratory: fact or fantasy? (Ledeboer NA, Dallas SD) J Clin Microbiol 2014 Sep;52(9):3140-6 PMID: 24648549 PMCID: PMC4313129 SCOPUS ID: 2-s2.0-84906872170 03/22/2014 29 Citations

Clinical evaluation of the walk-away specimen processor and ESwab for recovery of Streptococcus agalactiae isolates in prenatal screening specimens. (Buchan BW, Olson WJ, Mackey TL, Ledeboer NA) J Clin Microbiol 2014 Jun;52(6):2166-8 PMID: 24622104 PMCID: PMC4042734 SCOPUS ID: 2-s2.0-84901675733 03/14/2014 12 Citations

Photo quiz: a 5-year-old male with multiple pustules covering the entire scalp. Inflammatory Tinea Capitis. (Feih J, Ledeboer NA, Peppard WJ) J Clin Microbiol 2014 Apr;52(4):1027, 1312 PMID: 24619982 PMCID: PMC3993504 SCOPUS ID: 2-s2.0-84897149340 03/13/2014 1 Citation

ESwab as an optional collection device for use with the Affirm VPIII microbial test system. (Rivers CA, Lee JY, Sharples N, Ledeboer NA, Schwebke JR) J Clin Microbiol 2014 May;52(5):1698-700 PMID: 24523475 PMCID: PMC3993654 SCOPUS ID: 2-s2.0-84899583384 02/14/2014

Comparison of the BD MAX enteric bacterial panel to routine culture methods for detection of Campylobacter, enterohemorrhagic Escherichia coli (O157), Salmonella, and Shigella isolates in preserved stool specimens. (Anderson NW, Buchan BW, Ledeboer NA) J Clin Microbiol 2014 Apr;52(4):1222-4 PMID: 24430460 PMCID: PMC3993502 SCOPUS ID: 2-s2.0-84897133136 01/17/2014 46 Citations

Comparison of MALDI-TOF MS with HPLC and nucleic acid sequencing for the identification of Mycobacterium species in cultures using solid medium and broth. (Buchan BW, Riebe KM, Timke M, Kostrzewa M, Ledeboer NA) Am J Clin Pathol 2014 Jan;141(1):25-34 PMID: 24343734 SCOPUS ID: 2-s2.0-84894470655 12/18/2013 59 Citations

Light microscopy, culture, molecular, and serologic methods for detection of herpes simplex virus. (Anderson NW, Buchan BW, Ledeboer NA) J Clin Microbiol 2014 Jan;52(1):2-8 PMID: 24131689 PMCID: PMC3911428 SCOPUS ID: 2-s2.0-84891418459 10/18/2013 44 Citations

Multicenter evaluation of the Verigene Clostridium difficile nucleic acid assay. (Carroll KC, Buchan BW, Tan S, Stamper PD, Riebe KM, Pancholi P, Kelly C, Rao A, Fader R, Cavagnolo R, Watson W, Goering RV, Trevino EA, Weissfeld AS, Ledeboer NA) J Clin Microbiol 2013 Dec;51(12):4120-5 PMID: 24088862 PMCID: PMC3838056 SCOPUS ID: 2-s2.0-84889856754 10/04/2013 32 Citations

Clinical evaluation of a real-time PCR assay for identification of Salmonella, Shigella, Campylobacter (Campylobacter jejuni and C. coli), and shiga toxin-producing Escherichia coli isolates in stool specimens. (Buchan BW, Olson WJ, Pezewski M, Marcon MJ, Novicki T, Uphoff TS, Chandramohan L, Revell P, Ledeboer NA) J Clin Microbiol 2013 Dec;51(12):4001-7 PMID: 24048539 PMCID: PMC3838069 SCOPUS ID: 2-s2.0-84889869928 09/21/2013 57 Citations

Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test. (Buchan BW, Ginocchio CC, Manii R, Cavagnolo R, Pancholi P, Swyers L, Thomson RB Jr, Anderson C, Kaul K, Ledeboer NA) PLoS Med 2013;10(7):e1001478 PMID: 23843749 PMCID: PMC3699453 SCOPUS ID: 2-s2.0-84881261591 07/12/2013 101 Citations

Multicenter clinical evaluation of VRESelect agar for identification of vancomycin-resistant Enterococcus faecalis and Enterococcus faecium. (Anderson NW, Buchan BW, Young CL, Newton DW, Brenke C, Lapsley L, Granato PA, Ledeboer NA) J Clin Microbiol 2013 Aug;51(8):2758-60 PMID: 23761153 PMCID: PMC3719601 SCOPUS ID: 2-s2.0-84880637996 06/14/2013 14 Citations

Automation in clinical microbiology. (Bourbeau PP, Ledeboer NA) J Clin Microbiol 2013 Jun;51(6):1658-65 PMID: 23515547 PMCID: PMC3716104 SCOPUS ID: 2-s2.0-84878492392 03/22/2013 103 Citations

Multicenter clinical evaluation of the illumigene group A Streptococcus DNA amplification assay for detection of group A Streptococcus from pharyngeal swabs. (Anderson NW, Buchan BW, Mayne D, Mortensen JE, Mackey TL, Ledeboer NA) J Clin Microbiol 2013 May;51(5):1474-7 PMID: 23447639 PMCID: PMC3647941 SCOPUS ID: 2-s2.0-84876761270 03/01/2013 36 Citations

Advances in identification of clinical yeast isolates by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry. (Buchan BW, Ledeboer NA) J Clin Microbiol 2013 May;51(5):1359-66 PMID: 23426924 PMCID: PMC3647935 SCOPUS ID: 2-s2.0-84876705043 02/22/2013 62 Citations

Multicenter clinical evaluation of the portrait toxigenic C. difficile assay for detection of toxigenic Clostridium difficile strains in clinical stool specimens. (Buchan BW, Mackey TL, Daly JA, Alger G, Denys GA, Peterson LR, Kehl SC, Ledeboer NA) J Clin Microbiol 2012 Dec;50(12):3932-6 PMID: 23015667 PMCID: PMC3502949 SCOPUS ID: 2-s2.0-84869217890 09/28/2012 36 Citations

Automated detection of toxigenic Clostridium difficile in clinical samples: isothermal tcdB amplification coupled to array-based detection. (Hicke B, Pasko C, Groves B, Ager E, Corpuz M, Frech G, Munns D, Smith W, Warcup A, Denys G, Ledeboer NA, Lindsey W, Owen C, Rea L, Jenison R) J Clin Microbiol 2012 Aug;50(8):2681-7 PMID: 22675134 PMCID: PMC3421499 SCOPUS ID: 2-s2.0-84864410151 06/08/2012 20 Citations

Clostridium difficile: epidemiology, pathogenesis, management, and prevention of a recalcitrant healthcare-associated pathogen. (Badger VO, Ledeboer NA, Graham MB, Edmiston CE Jr) JPEN J Parenter Enteral Nutr 2012 Nov;36(6):645-62 PMID: 22577120 SCOPUS ID: 2-s2.0-84867630570 05/12/2012 53 Citations

Comparison of BD Phoenix and bioMérieux Vitek 2 automated systems for the detection of macrolide-lincosamide-streptogramin B resistance among clinical isolates of Staphylococcus. (Buchan BW, Anderson NW, Ledeboer NA) Diagn Microbiol Infect Dis 2012 Mar;72(3):291-4 PMID: 22322000 SCOPUS ID: 2-s2.0-84856612590 02/11/2012 8 Citations

Comparison of the MALDI Biotyper system using Sepsityper specimen processing to routine microbiological methods for identification of bacteria from positive blood culture bottles. (Buchan BW, Riebe KM, Ledeboer NA) J Clin Microbiol 2012 Feb;50(2):346-52 PMID: 22162549 PMCID: PMC3264150 SCOPUS ID: 2-s2.0-84856206216 12/14/2011 156 Citations

Effects of solid-medium type on routine identification of bacterial isolates by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry. (Anderson NW, Buchan BW, Riebe KM, Parsons LN, Gnacinski S, Ledeboer NA) J Clin Microbiol 2012 Mar;50(3):1008-13 PMID: 22162546 PMCID: PMC3295166 SCOPUS ID: 2-s2.0-84857423338 12/14/2011 75 Citations

Things are not always what they appear to be. (Anderson N, Ledeboer NA) J Clin Microbiol 2011 Nov;49(11):3727, 4030 PMID: 22042829 PMCID: PMC3209076 SCOPUS ID: 2-s2.0-80355145131 11/02/2011

A rare case of pneumocystis jirovecii pneumonia: In a nonimmunocompromised host (Patel JJ, Graham MB, Presberg KW, Ledeboer NA, Lipchik RJ) Infectious Diseases in Clinical Practice November 2011;19(6) SCOPUS ID: 2-s2.0-80855132856 11/01/2011

Evaluation of a microarray-based genotyping assay for the rapid detection of cytochrome P450 2C19 *2 and *3 polymorphisms from whole blood using nanoparticle probes. (Buchan BW, Peterson JF, Cogbill CH, Anderson DK, Ledford JS, White MN, Quigley NB, Jannetto PJ, Ledeboer NA) Am J Clin Pathol 2011 Oct;136(4):604-8 PMID: 21917683 SCOPUS ID: 2-s2.0-80053464779 09/16/2011 21 Citations

Molecular detection of resistance determinants (Ledeboer NA, Hodinka RL) Journal of Clinical Microbiology September 2011;49(9 SUPPL.) SCOPUS ID: 2-s2.0-80053217117 09/01/2011 22 Citations

A rare presentation of a common disease. (Anderson N, Rao N, Ledeboer NA) J Clin Microbiol 2011 Aug;49(8):2785; 3112 PMID: 21799090 PMCID: PMC3147748 SCOPUS ID: 2-s2.0-79960936233 07/30/2011 1 Citation

A tile layer's nightmare. (Buonaccorsi JN, Ledeboer NA) J Clin Microbiol 2011 May;49(5):1707, 2083 PMID: 21525232 PMCID: PMC3122674 SCOPUS ID: 2-s2.0-79955548748 04/29/2011

Performance of the BD GeneOhm MRSA achromopeptidase assay for real-time PCR detection of methicillin-resistant Staphylococcus aureus in nasal specimens. (Patel PA, Ledeboer NA, Ginocchio CC, Condon S, Bouchard S, Qin P, Karchmer T, Peterson LR) J Clin Microbiol 2011 Jun;49(6):2266-8 PMID: 21508148 PMCID: PMC3122740 SCOPUS ID: 2-s2.0-79957516092 04/22/2011 24 Citations

Multicenter comparison of the Vitek 2 antifungal susceptibility test with the CLSI broth microdilution reference method for testing caspofungin, micafungin, and posaconazole against Candida spp. (Peterson JF, Pfaller MA, Diekema DJ, Rinaldi MG, Riebe KM, Ledeboer NA) J Clin Microbiol 2011 May;49(5):1765-71 PMID: 21430096 PMCID: PMC3122687 SCOPUS ID: 2-s2.0-79955527633 03/25/2011 27 Citations

Tirandamycins from Streptomyces sp. 17944 inhibiting the parasite Brugia malayi asparagine tRNA synthetase. (Yu Z, Vodanovic-Jankovic S, Ledeboer N, Huang SX, Rajski SR, Kron M, Shen B) Org Lett 2011 Apr 15;13(8):2034-7 PMID: 21405052 PMCID: PMC3074013 SCOPUS ID: 2-s2.0-79955388062 03/17/2011 55 Citations

Acinetobacter infections - Epidemiology and pathogenesis of a significant healthcare-associated pathogen (Buchan BW, Ledeboer NA, Edmiston CE) Healthcare Infection March 2011;16(1):6-17 SCOPUS ID: 2-s2.0-79953165771 01/01/2011 2 Citations

Identification of two borderline oxacillin-resistant strains of Staphylococcus aureus from routine nares swab specimens by one of three chromogenic agars evaluated for the detection of MRSA. (Buchan BW, Ledeboer NA) Am J Clin Pathol 2010 Dec;134(6):921-7 PMID: 21088156 SCOPUS ID: 2-s2.0-78649655793 11/23/2010 10 Citations

Evaluation of Spectra VRE, a new chromogenic agar medium designed to screen for vancomycin-resistant Enterococcus faecalis and Enterococcus faecium. (Peterson JF, Doern CD, Kallstrom G, Riebe KM, Sander T, Dunne WM Jr, Ledeboer NA) J Clin Microbiol 2010 Dec;48(12):4627-9 PMID: 20943872 PMCID: PMC3008490 SCOPUS ID: 2-s2.0-78650066607 10/15/2010 18 Citations

Real-time detection of influenza a, influenza B, and respiratory syncytial virus a and B in respiratory specimens by use of nanoparticle probes. (Jannetto PJ, Buchan BW, Vaughan KA, Ledford JS, Anderson DK, Henley DC, Quigley NB, Ledeboer NA) J Clin Microbiol 2010 Nov;48(11):3997-4002 PMID: 20826644 PMCID: PMC3020893 SCOPUS ID: 2-s2.0-78049514476 09/10/2010 35 Citations

Epidemiologic Observations from Passive and Targeted Surveillance during the First Wave of the 2009 H1N1 Influenza Pandemic in Milwaukee, WI. (Kumar S, Chusid MJ, Willoughby RE, Havens PL, Kehl SC, Ledeboer NA, Simpson P, Vandyke M, Davis E, Gaffney K, Li SH, Bose ME, Henrickson KJ) Viruses 2010;2(4):782-795 PMID: 20648234 PMCID: PMC2905828 SCOPUS ID: 2-s2.0-78650647583 07/22/2010 12 Citations

Alternative use for spectra MRSA chromogenic agar in detection of methicillin-resistant Staphylococcus aureus from positive blood cultures. (Peterson JF, Dionisio AA, Riebe KM, Hall GS, Wilson DA, Whittier S, Dipersio JR, Ledeboer NA) J Clin Microbiol 2010 Jun;48(6):2265-7 PMID: 20392925 PMCID: PMC2884473 SCOPUS ID: 2-s2.0-77952896361 04/16/2010 6 Citations

Erratum: Spectra MRSA, a new chromogenic agar medium to screen for methicillin-resistant Staphylococcus aureus (Journal of Clinical Microbiology (2010) 48:1 (215-219)) (Peterson JF, Riebe KM, Hall GS, Wilson D, Whittier S, Palavecino E, Ledeboer NA) Journal of Clinical Microbiology 1 April 2010;48(4):1510 SCOPUS ID: 2-s2.0-77950507698 04/01/2010

Spectra MRSA, a new chromogenic agar medium to screen for methicillin-resistant Staphylococcus aureus. (Peterson JF, Riebe KM, Hall GS, Wilson D, Whittier S, Palavecino E, Ledeboer NA) J Clin Microbiol 2010 Jan;48(1):215-9 PMID: 19889898 PMCID: PMC2812258 SCOPUS ID: 2-s2.0-73949132153 11/06/2009 26 Citations

Introduction of a Novel Swine-Origin Influenza A (H1N1) Virus into Milwaukee, Wisconsin in 2009. (Kumar S, Chusid MJ, Willoughby RE, Havens PL, Kehl SC, Ledeboer NA, Li SH, Henrickson KJ) Viruses 2009 Jun 01;1(1):72-83 PMID: 19865496 PMCID: PMC2768288 SCOPUS ID: 2-s2.0-69949099955 10/30/2009 15 Citations

Rapid multiplex reverse transcription-PCR typing of influenza A and B virus, and subtyping of influenza A virus into H1, 2, 3, 5, 7, 9, N1 (human), N1 (animal), N2, and N7, including typing of novel swine origin influenza A (H1N1) virus, during the 2009 outbreak in Milwaukee, Wisconsin. (He J, Bose ME, Beck ET, Fan J, Tiwari S, Metallo J, Jurgens LA, Kehl SC, Ledeboer N, Kumar S, Weisburg W, Henrickson KJ) J Clin Microbiol 2009 Sep;47(9):2772-8 PMID: 19641063 PMCID: PMC2738083 SCOPUS ID: 2-s2.0-69949096010 07/31/2009 77 Citations

Rapid semiautomated subtyping of influenza virus species during the 2009 swine origin influenza A H1N1 virus epidemic in Milwaukee, Wisconsin. (Bose ME, Beck ET, Ledeboer N, Kehl SC, Jurgens LA, Patitucci T, Witt L, LaGue E, Darga P, He J, Fan J, Kumar S, Henrickson KJ) J Clin Microbiol 2009 Sep;47(9):2779-86 PMID: 19641066 PMCID: PMC2738075 SCOPUS ID: 2-s2.0-69949100084 07/31/2009 32 Citations

Detection and quantification of hepatitis C virus (HCV) by MultiCode-RTx real-time PCR targeting the HCV 3' untranslated region. (Mulligan EK, Germer JJ, Arens MQ, D'Amore KL, Di Bisceglie A, Ledeboer NA, Moser MJ, Newman AC, O'Guin AK, Olivo PD, Podzorski DS, Vaughan KA, Yao JD, Elagin SA, Johnson SC) J Clin Microbiol 2009 Aug;47(8):2635-8 PMID: 19535519 PMCID: PMC2725663 SCOPUS ID: 2-s2.0-68549083456 06/19/2009 7 Citations

Linezolid for the treatment of drug-resistant infections. (Herrmann DJ, Peppard WJ, Ledeboer NA, Theesfeld ML, Weigelt JA, Buechel BJ) Expert Rev Anti Infect Ther 2008 Dec;6(6):825-48 PMID: 19053895 SCOPUS ID: 2-s2.0-59449100218 12/05/2008 26 Citations

A new chromogenic agar medium, chromID VRE, to screen for vancomycin-resistant Enterococcus faecium and Enterococcus faecalis. (Ledeboer NA, Tibbetts RJ, Dunne WM) Diagn Microbiol Infect Dis 2007 Dec;59(4):477-9 PMID: 17889490 SCOPUS ID: 2-s2.0-36549075051 09/25/2007 26 Citations

Tigecycline for treatment of pneumonia and empyema caused by carbapenemase-producing Klebsiella pneumoniae. (Daly MW, Riddle DJ, Ledeboer NA, Dunne WM, Ritchie DJ) Pharmacotherapy 2007 Jul;27(7):1052-7 PMID: 17594211 SCOPUS ID: 2-s2.0-34250828957 06/28/2007 66 Citations

Evaluation of a novel chromogenic agar medium for isolation and differentiation of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis isolates. (Ledeboer NA, Das K, Eveland M, Roger-Dalbert C, Mailler S, Chatellier S, Dunne WM) J Clin Microbiol 2007 May;45(5):1556-60 PMID: 17329453 PMCID: PMC1865861 SCOPUS ID: 2-s2.0-34248595510 03/03/2007 28 Citations

Salmonella enterica serovar Typhimurium requires the Lpf, Pef, and Tafi fimbriae for biofilm formation on HEp-2 tissue culture cells and chicken intestinal epithelium. (Ledeboer NA, Frye JG, McClelland M, Jones BD) Infect Immun 2006 Jun;74(6):3156-69 PMID: 16714543 PMCID: PMC1479237 SCOPUS ID: 2-s2.0-33646910168 05/23/2006 111 Citations

The Dangers of Yardwork (Ledeboer N) Tietz's Applied Laboratory Medicine: Second Edition 18 May 2006:329-333 SCOPUS ID: 2-s2.0-84889629668 05/18/2006

Exopolysaccharide sugars contribute to biofilm formation by Salmonella enterica serovar typhimurium on HEp-2 cells and chicken intestinal epithelium. (Ledeboer NA, Jones BD) J Bacteriol 2005 May;187(9):3214-26 PMID: 15838049 PMCID: PMC1082824 SCOPUS ID: 2-s2.0-17644418718 04/20/2005 101 Citations

Differential binding to and biofilm formation on, HEp-2 cells by Salmonella enterica serovar Typhimurium is dependent upon allelic variation in the fimH gene of the fim gene cluster. (Boddicker JD, Ledeboer NA, Jagnow J, Jones BD, Clegg S) Mol Microbiol 2002 Sep;45(5):1255-65 PMID: 12207694 SCOPUS ID: 2-s2.0-0036042644 09/05/2002 106 Citations

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Nathan A. Ledeboer PhD

Vice Chair, Professor

Publications (135)