Medical College of Wisconsin
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Naveenkumar Chandrashekar

Naveenkumar Chandrashekar profile photo picture

Postdoctoral Researcher 2

Institution: Medical College of Wisconsin
Department: Surgery
Division: Surgery Operations

image of /images/ORCIDiD_icon16x16.png   https://orcid.org/0000-0003-4951-1277


I am willing to collaborate on research projects.

Research Areas of Interest

  • Colonic Neoplasms
  • Pancreatic Neoplasms
  • Precision Medicine

    • Publications (22)

  • Effects of Ursolic acid on Diabetic Nephropathy – A Review”. In: Organic acids in Diabetes – Applications and Mechanisms (P Anandakumar, C Naveenkumar, S Nabendu and MK Vanitha) CRC Press ISBN:9781003495802 10/28/2025    
  • Molecular insights into the anticancer properties of dieckol: a comprehensive review. (Pandi A, Sen N, Kalappan VM, Chandrashekar N, Perumal MK) Naunyn Schmiedebergs Arch Pharmacol 2026 Feb;399(3):3303-3319 PMID: 41125915 SCOPUS ID: 2-s2.0-105019542211 10/23/2025       1 Citation
  • Ex-vivo organotypic tumor model of metastatic core biopsy serve as a pragmatic platform for real-time personalized therapy in pancreatic adenocarcinoma. (a) Chandrashekar N, Yuan J, Stasny N, Aldakkak M, Kamgar M, McFall T, Lytle N, Grewal J, Stark A, Guerra O, Phan A, Hall W, Erickson B, Kothari A, Clarke C, Christians K, Rilling W, Tolat P, Evans D, David Seo Y.) Cancer Research 85(18_Suppl_3):Abstract nr B008. 09/17/2025    
  • “Causes, Symptoms, and Treatment of Epstein-Barr Virus infection”. In: Viral Oncology – New Approaches to molecular cancer therapeutics. (C Naveenkumar and P Anandakumar. ) CRC Press v1, pp 161-164. ISBN:9781003516651. 03/20/2025    
  • The emerging role of phospholipase D in cancer progression and therapeutics”. In: Chakraborti S (eds) Phospholipases in Physiology and Pathology (C Naveenkumar and P Anandakumar) Elsevier Academic Press pp 371-385. ISBN:978-0-323-95687-1. 06/14/2023    
  • Phospholipases: Insights into the potential role of cell death”. In: Chakraborti S (eds) Phospholipases in Physiology and Pathology (C Naveenkumar and P Anandakumar) Elsevier Academic Press pp 269-277. ISBN: 978-0-323-95687-1 01/17/2023    
  • Baicalein: A review on its anti-cancer effects and mechanisms in lung carcinoma. (Chandrashekar N, Pandi A) J Food Biochem 2022 Sep;46(9):e14230 PMID: 35543192 SCOPUS ID: 2-s2.0-85129760138 05/12/2022       52 Citations
  • Baicalein inhibits cell proliferation and enhances apoptosis in human A549 cells and benzo(a)pyrene-induced pulmonary carcinogenesis in mice. (Chandrashekar N, Subramanian R, Thiruvengadam D) J Biochem Mol Toxicol 2022 Jul;36(7):e23053 PMID: 35332611 SCOPUS ID: 2-s2.0-85127276129 03/26/2022       8 Citations
  • Montelukast, a CysLT1 receptor antagonist, reduces colon cancer stemness and tumor burden in a mouse xenograft model of human colon cancer. (Bellamkonda K, Satapathy SR, Douglas D, Chandrashekar N, Selvanesan BC, Liu M, Savari S, Jonsson G, Sjölander A) Cancer Lett 2018 Nov 28;437:13-24 PMID: 30144515 SCOPUS ID: 2-s2.0-85052505972 08/26/2018       28 Citations
  • Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer. (Osman J, Savari S, Chandrashekar NK, Bellamkonda K, Douglas D, Sjölander A) Oncotarget 2017 May 23;8(21):34773-34786 PMID: 28410235 PMCID: PMC5471010 SCOPUS ID: 2-s2.0-85019888210 04/15/2017       29 Citations
  • The eicosanoids leukotriene D4 and prostaglandin E2 promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model. (Bellamkonda K, Chandrashekar NK, Osman J, Selvanesan BC, Savari S, Sjölander A) BMC Cancer 2016 Jul 07;16:425 PMID: 27388564 PMCID: PMC4937611 SCOPUS ID: 2-s2.0-84978811128 07/09/2016       29 Citations
  • Cysteinyl leukotriene 1 receptor influences intestinal polyp incidence in a gender-specific manner in the ApcMin/+ mouse model. (Savari S, Chandrashekar NK, Osman J, Douglas D, Bellamkonda K, Jönsson G, Juhas M, Greicius G, Pettersson S, Sjölander A) Carcinogenesis 2016 May;37(5):491-9 PMID: 26979937 SCOPUS ID: 2-s2.0-84964884533 03/17/2016       27 Citations
  • The Anticancer Role of Capsaicin in Experimentallyinduced Lung Carcinogenesis. (Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Asokkumar S, Naveenkumar C, Raghunandhakumar S, Vanitha MK, Devaki T) J Pharmacopuncture 2015 Jun;18(2):19-25 PMID: 26120484 PMCID: PMC4481395 06/30/2015    
  • Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular carcinoma. (Raghunandhakumar S, Paramasivam A, Senthilraja S, Naveenkumar C, Asokkumar S, Binuclara J, Jagan S, Anandakumar P, Devaki T) Toxicol Lett 2013 Oct 23;223(1):60-72 PMID: 24012840 SCOPUS ID: 2-s2.0-84885132843 09/10/2013       75 Citations
  • Mitigating role of baicalein on lysosomal enzymes and xenobiotic metabolizing enzyme status during lung carcinogenesis of Swiss albino mice induced by benzo(a)pyrene. (Naveenkumar C, Raghunandakumar S, Asokkumar S, Binuclara J, Rajan B, Premkumar T, Devaki T) Fundam Clin Pharmacol 2014 Jun;28(3):310-22 PMID: 23834621 SCOPUS ID: 2-s2.0-84899079277 07/10/2013       20 Citations
  • Growth of HCT-116 colon cancer xenografts is inhibited by CysLT1R antagonists (Sjölander A, Savari S, Zhang Y, Sime W, Chandrashekar NK; Liu M) Cancer Research 73(8 Suppl):Abstract nr 2721. 04/06/2013    
  • Baicalein abrogates reactive oxygen species (ROS)-mediated mitochondrial dysfunction during experimental pulmonary carcinogenesis in vivo. (Naveenkumar C, Raghunandhakumar S, Asokkumar S, Devaki T) Basic Clin Pharmacol Toxicol 2013 Apr;112(4):270-81 PMID: 23061789 SCOPUS ID: 2-s2.0-84875060273 10/16/2012       43 Citations
  • Capsaicin inhibits benzo(a)pyrene-induced lung carcinogenesis in an in vivo mouse model. (Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Asokkumar S, Naveenkumar C, Raghunandhakumar S, Devaki T) Inflamm Res 2012 Nov;61(11):1169-75 PMID: 22735861 SCOPUS ID: 2-s2.0-84868144302 06/28/2012       69 Citations
  • Baicalein inhibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo. (Chandrashekar N, Selvamani A, Subramanian R, Pandi A, Thiruvengadam D) Toxicol Appl Pharmacol 2012 May 15;261(1):10-21 PMID: 22369883 SCOPUS ID: 2-s2.0-84860518210 03/01/2012       87 Citations
  • Antiproliferative and antioxidant potential of beta-ionone against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice. (Asokkumar S, Naveenkumar C, Raghunandhakumar S, Kamaraj S, Anandakumar P, Jagan S, Devaki T) Mol Cell Biochem 2012 Apr;363(1-2):335-45 PMID: 22187222 SCOPUS ID: 2-s2.0-84857905171 12/22/2011       54 Citations
  • Potent antitumor and antineoplastic efficacy of baicalein on benzo(a)pyrene-induced experimental pulmonary tumorigenesis. (Naveenkumar C, Asokkumar S, Raghunandhakumar S, Jagan S, Anandakumar P, Augustine TA, Kamaraj S, Devaki T) Fundam Clin Pharmacol 2012 Apr;26(2):259-70 PMID: 21323996 SCOPUS ID: 2-s2.0-84858066600 02/18/2011       28 Citations
  • Capsaicin alleviates the imbalance in xenobiotic metabolizing enzymes and tumor markers during experimental lung tumorigenesis. (Anandakumar P, Kamaraj S, Jagan S, Ramakrishnan G, Naveenkumar C, Asokkumar S, Devaki T) Mol Cell Biochem 2009 Nov;331(1-2):135-43 PMID: 19449198 SCOPUS ID: 2-s2.0-74049129532 05/19/2009       35 Citations
    • Last update: 04/14/2026