Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Nicholas N. Jarjour MBBS

Assistant Professor

Institution: Medical College of Wisconsin
Department: Biochemistry

View Curriculum Vitae

Publications (20)

  • Collaboration between interleukin-7 and -15 enables adaptation of tissue-resident and circulating memory CD8+ T cells to cytokine deficiency. (Jarjour NN, Dalzell TS, Maurice NJ, Wanhainen KM, Peng C, O'Flanagan SD, DePauw TA, Block KE, Valente WJ, Ashby KM, Masopust D, Jameson SC) Immunity 2025 Mar 11;58(3):616-631.e5 PMID: 40023156 PMCID: PMC13329436 SCOPUS ID: 2-s2.0-86000362466 03/03/2025       28 Citations
  • Human ACE2 Gene Replacement Mice Support SARS-CoV-2 Viral Replication and Nonlethal Disease Progression. (Thiede JM, Dick JK, Jarjour NN, Krishna VD, Qian L, Sangala J, Benzow K, Karanjeet K, Chin S, Rainwater O, Cheeran MC, Hogquist KA, Jameson SC, Hart GT, Bold TD, Koob MD) Immunohorizons 2024 Sep 01;8(9):712-720 PMID: 39287601 PMCID: PMC11447706 SCOPUS ID: 2-s2.0-85204418695 09/17/2024       5 Citations
  • Steady-state, therapeutic, and helminth-induced IL-4 compromise protective CD8 T cell bystander activation. (Maurice NJ, Dalzell TS, Jarjour NN, DePauw TA, Jameson SC) bioRxiv 2024 Jun 12 PMID: 38915668 PMCID: PMC11195063 06/25/2024    
  • Collaboration between IL-7 and IL-15 enables adaptation of tissue-resident and circulating memory CD8+ T cells. (Jarjour NN, Dalzell TS, Maurice NJ, Wanhainen KM, Peng C, DePauw TA, Block KE, Valente WJ, Ashby KM, Masopust D, Jameson SC) bioRxiv 2024 Jun 03 PMID: 38895229 PMCID: PMC11185530 06/19/2024    
  • BHLHE40 Mediates Cross-Talk between Pathogenic TH17 Cells and Myeloid Cells during Experimental Autoimmune Encephalomyelitis. (Cook ME, Shchukina I, Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Webber AM, Zaitsev K, Artyomov MN, Edelson BT) Immunohorizons 2023 Nov 01;7(11):737-746 PMID: 37934060 PMCID: PMC10695412 SCOPUS ID: 2-s2.0-85176495848 11/07/2023       5 Citations
  • APLs and Oranges: Induction of T Cell Anergy by Altered Peptide Ligands. (Jarjour NN, Jameson SC) J Immunol 2023 Sep 01;211(5):709-710 PMID: 37603860 SCOPUS ID: 2-s2.0-85168439072 08/21/2023    
  • Responsiveness to interleukin-15 therapy is shared between tissue-resident and circulating memory CD8+ T cell subsets. (Jarjour NN, Wanhainen KM, Peng C, Gavil NV, Maurice NJ, Borges da Silva H, Martinez RJ, Dalzell TS, Huggins MA, Masopust D, Hamilton SE, Jameson SC) Proc Natl Acad Sci U S A 2022 Oct 25;119(43):e2209021119 PMID: 36260745 PMCID: PMC9618124 SCOPUS ID: 2-s2.0-85140415634 10/20/2022       18 Citations
  • Mesothelium-Derived Factors Shape GATA6-Positive Large Cavity Macrophages. (Lai CW, Bagadia P, Barisas DAG, Jarjour NN, Wong R, Ohara T, Muegge BD, Lu Q, Xiong S, Edelson BT, Murphy KM, Stappenbeck TS) J Immunol 2022 Aug 15;209(4):742-750 PMID: 35868637 SCOPUS ID: 2-s2.0-85136758821 07/23/2022       9 Citations
  • Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C. (Zhao M, Ren K, Xiong X, Xin Y, Zou Y, Maynard JC, Kim A, Battist AP, Koneripalli N, Wang Y, Chen Q, Xin R, Yang C, Huang R, Yu J, Huang Z, Zhang Z, Wang H, Wang D, Xiao Y, Salgado OC, Jarjour NN, Hogquist KA, Revelo XS, Burlingame AL, Gao X, von Moltke J, Lin Z, Ruan HB) Immunity 2022 Jul 12;55(7):1327 PMID: 35830826 PMCID: PMC9336012 SCOPUS ID: 2-s2.0-85133986937 07/14/2022       5 Citations
  • Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C. (Zhao M, Ren K, Xiong X, Xin Y, Zou Y, Maynard JC, Kim A, Battist AP, Koneripalli N, Wang Y, Chen Q, Xin R, Yang C, Huang R, Yu J, Huang Z, Zhang Z, Wang H, Wang D, Xiao Y, Salgado OC, Jarjour NN, Hogquist KA, Revelo XS, Burlingame AL, Gao X, von Moltke J, Lin Z, Ruan HB) Immunity 2022 Apr 12;55(4):623-638.e5 PMID: 35385697 PMCID: PMC9109499 SCOPUS ID: 2-s2.0-85127492845 04/07/2022       108 Citations
  • BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy. (Salmon AJ, Shavkunov AS, Miao Q, Jarjour NN, Keshari S, Esaulova E, Williams CD, Ward JP, Highsmith AM, Pineda JE, Taneja R, Chen K, Edelson BT, Gubin MM) Cancer Immunol Res 2022 May 03;10(5):597-611 PMID: 35181783 PMCID: PMC9164498 SCOPUS ID: 2-s2.0-85129996880 02/20/2022       32 Citations
  • Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells. (Peng C, Huggins MA, Wanhainen KM, Knutson TP, Lu H, Georgiev H, Mittelsteadt KL, Jarjour NN, Wang H, Hogquist KA, Campbell DJ, Borges da Silva H, Jameson SC) Immunity 2022 Jan 11;55(1):98-114.e5 PMID: 34932944 PMCID: PMC8755622 SCOPUS ID: 2-s2.0-85122271938 12/22/2021       92 Citations
  • T Cell Memory: Understanding COVID-19. (Jarjour NN, Masopust D, Jameson SC) Immunity 2021 Jan 12;54(1):14-18 PMID: 33406391 PMCID: PMC7749639 SCOPUS ID: 2-s2.0-85099006544 01/07/2021       136 Citations
  • Transcription Factor Bhlhe40 in Immunity and Autoimmunity. (Cook ME, Jarjour NN, Lin CC, Edelson BT) Trends Immunol 2020 Nov;41(11):1023-1036 PMID: 33039338 PMCID: PMC7606821 SCOPUS ID: 2-s2.0-85092261549 10/12/2020       113 Citations
  • BHLHE40 Promotes TH2 Cell-Mediated Antihelminth Immunity and Reveals Cooperative CSF2RB Family Cytokines. (Jarjour NN, Bradstreet TR, Schwarzkopf EA, Cook ME, Lai CW, Huang SC, Taneja R, Stappenbeck TS, Van Dyken SJ, Urban JF Jr, Edelson BT) J Immunol 2020 Feb 15;204(4):923-932 PMID: 31900338 PMCID: PMC7002269 SCOPUS ID: 2-s2.0-85079020866 01/05/2020       28 Citations
  • Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity. (Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Lin CC, Huang SC, Lai CW, Cook ME, Taneja R, Stappenbeck TS, Randolph GJ, Artyomov MN, Urban JF Jr, Edelson BT) Nat Immunol 2019 Jun;20(6):687-700 PMID: 31061528 PMCID: PMC6531324 SCOPUS ID: 2-s2.0-85065302395 05/08/2019       68 Citations
  • Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity. (Zhang N, Czepielewski RS, Jarjour NN, Erlich EC, Esaulova E, Saunders BT, Grover SP, Cleuren AC, Broze GJ, Edelson BT, Mackman N, Zinselmeyer BH, Randolph GJ) J Exp Med 2019 Jun 03;216(6):1291-1300 PMID: 31048328 PMCID: PMC6547866 SCOPUS ID: 2-s2.0-85067217186 05/03/2019       111 Citations
  • Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection. (Huynh JP, Lin CC, Kimmey JM, Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Shpynov O, Weaver CT, Taneja R, Artyomov MN, Edelson BT, Stallings CL) J Exp Med 2018 Jul 02;215(7):1823-1838 PMID: 29773644 PMCID: PMC6028511 SCOPUS ID: 2-s2.0-85054630864 05/19/2018       97 Citations
  • Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer. (Gounder AP, Yokoyama CC, Jarjour NN, Bricker TL, Edelson BT, Boon ACM) PLoS Pathog 2018 Apr;14(4):e1007001 PMID: 29698474 PMCID: PMC5940246 SCOPUS ID: 2-s2.0-85046484963 04/27/2018       24 Citations
  • IL-1-induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation. (Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Chou C, Archambault AS, Sim J, Zinselmeyer BH, Carrero JA, Wu GF, Taneja R, Artyomov MN, Russell JH, Edelson BT) J Exp Med 2016 Feb 08;213(2):251-71 PMID: 26834156 PMCID: PMC4749922 SCOPUS ID: 2-s2.0-84961196714 02/03/2016       86 Citations
    • Last update: 09/02/2026