Medical College of Wisconsin
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Seung Min Shin PhD

Seung Min Shin PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology
Division: Research

Member of the Cardiovascular Center

View Curriculum Vitae

Publications (23)

  • Increased keratinocyte activity and PIEZO1 signaling contribute to paclitaxel-induced mechanical hypersensitivity. (Mikesell AR, Isaeva E, Schulte ML, Menzel AD, Sriram A, Prahl MM, Shin SM, Sadler KE, Yu H, Stucky CL) Sci Transl Med 2024 Dec 11;16(777):eadn5629 PMID: 39661703 SCOPUS ID: 2-s2.0-85211969507 12/11/2024    
  • Inhibition of Soluble Epoxide Hydrolase Ameliorates Cerebral Blood Flow Autoregulation and Cognition in Alzheimer's Disease and Diabetes-Related Dementia Rat Models. (Tang C, Border JJ, Zhang H, Gregory A, Bai S, Fang X, Liu Y, Wang S, Hwang SH, Gao W, Morgan GC, Smith J, Bunn D, Cantwell C, Wagner KM, Morisseau C, Yang J, Shin SM, O'Herron P, Bagi Z, Filosa JA, Dong Y, Yu H, Hammock BD, Roman RJ, Fan F) bioRxiv 2024 Aug 31 PMID: 39257786 PMCID: PMC11383657 09/11/2024    
  • Peripherally targeted analgesia via AAV-mediated sensory neuron-specific inhibition of multiple pronociceptive sodium channels. (Shin SM, Itson-Zoske B, Fan F, Xiao Y, Qiu C, Cummins TR, Hogan QH, Yu H) J Clin Invest 2024 May 09;134(13) PMID: 38722683 PMCID: PMC11213509 SCOPUS ID: 2-s2.0-85197962514 05/10/2024    
  • Impact of knockout of dual-specificity protein phosphatase 5 on structural and mechanical properties of rat middle cerebral arteries: implications for vascular aging. (Tang C, Zhang H, Border JJ, Liu Y, Fang X, Jefferson JR, Gregory A, Johnson C, Lee TJ, Bai S, Sharma A, Shin SM, Yu H, Roman RJ, Fan F) Geroscience 2024 Jun;46(3):3135-3147 PMID: 38200357 PMCID: PMC11009215 SCOPUS ID: 2-s2.0-85182225045 01/11/2024    
  • Keratinocyte Piezo1 drives paclitaxel-induced mechanical hypersensitivity. (Mikesell AR, Isaeva E, Schulte ML, Menzel AD, Sriram A, Prahl MM, Shin SM, Sadler KE, Yu H, Stucky CL) bioRxiv 2023 Dec 13 PMID: 38168305 PMCID: PMC10760029 01/04/2024    
  • Role of Dusp5 KO on Vascular Properties of Middle Cerebral Artery in Rats. (Tang C, Zhang H, Border JJ, Liu Y, Fang X, Jefferson JR, Gregory A, Johnson C, Lee TJ, Bai S, Sharma A, Shin SM, Yu H, Roman RJ, Fan F) bioRxiv 2023 Dec 06 PMID: 38106132 PMCID: PMC10723354 12/18/2023    
  • Selective RNAi-silencing of Schwann cell Piezo1 alleviates mechanical hypersensitization following peripheral nerve injury. (Itson-Zoske B, Gani U, Mikesell A, Qiu C, Fan F, Stucky C, Hogan Q, Shin SM, Yu H) Res Sq 2023 Oct 16 PMID: 37886453 PMCID: PMC10602140 10/27/2023    
  • Longitudinal characterization of cerebral hemodynamics in the TgF344-AD rat model of Alzheimer’s disease (Fang X, Tang C, Zhang H, Border JJ, Liu Y, Shin SM, Yu H, Roman RJ, Fan F) GeroScience June 2023;45(3):1471-1490 SCOPUS ID: 2-s2.0-85150306159 06/01/2023       4 Citations
  • Peripheral sensory neurons and non-neuronal cells express functional Piezo1 channels. (Shin SM, Itson-Zoske B, Fan F, Gani U, Rahman M, Hogan QH, Yu H) Mol Pain 2023;19:17448069231174315 PMID: 37247618 PMCID: PMC10240879 SCOPUS ID: 2-s2.0-85160467897 05/30/2023       12 Citations
  • Selective block of sensory neuronal T-type/Cav3.2 activity mitigates neuropathic pain behavior in a rat model of osteoarthritis pain. (Itson-Zoske B, Shin SM, Xu H, Qiu C, Fan F, Hogan QH, Yu H) Arthritis Res Ther 2022 Jul 16;24(1):168 PMID: 35842727 PMCID: PMC9287929 SCOPUS ID: 2-s2.0-85134262185 07/17/2022       3 Citations
  • Targeting intrinsically disordered regions facilitates discovery of calcium channels 3.2 inhibitory peptides for adeno-associated virus-mediated peripheral analgesia. (Shin SM, Lauzadis J, Itson-Zoske B, Cai Y, Fan F, Natarajan GK, Kwok WM, Puopolo M, Hogan QH, Yu H) Pain 2022 Dec 01;163(12):2466-2484 PMID: 35420557 PMCID: PMC9562599 SCOPUS ID: 2-s2.0-85134128027 04/15/2022       1 Citation
  • S-SCAM inhibits Axin-dependent synaptic function of GSK3β in a sex-dependent manner. (Kearney G, Grau D, Nieves Torres D, Shin SM, Lee SH) Sci Rep 2022 Mar 08;12(1):4090 PMID: 35260764 PMCID: PMC8904762 SCOPUS ID: 2-s2.0-85126076405 03/10/2022       1 Citation
  • Piezo2 mechanosensitive ion channel is located to sensory neurons and nonneuronal cells in rat peripheral sensory pathway: implications in pain. (Shin SM, Moehring F, Itson-Zoske B, Fan F, Stucky CL, Hogan QH, Yu H) Pain 2021 Nov 01;162(11):2750-2768 PMID: 34285153 PMCID: PMC8526381 SCOPUS ID: 2-s2.0-85119089549 07/22/2021       45 Citations
  • Enhanced T-type calcium channel 3.2 activity in sensory neurons contributes to neuropathic-like pain of monosodium iodoacetate-induced knee osteoarthritis. (Shin SM, Cai Y, Itson-Zoske B, Qiu C, Hao X, Xiang H, Hogan QH, Yu H) Mol Pain 2020;16:1744806920963807 PMID: 33054557 PMCID: PMC7570798 SCOPUS ID: 2-s2.0-85092743914 10/16/2020       20 Citations
  • Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain. (Shin SM, Itson-Zoske B, Cai Y, Qiu C, Pan B, Stucky CL, Hogan QH, Yu H) Mol Pain 2020;16:1744806920925425 PMID: 32484015 PMCID: PMC7268132 SCOPUS ID: 2-s2.0-85085909943 06/03/2020       31 Citations
  • Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain. (Shin SM, Wang F, Qiu C, Itson-Zoske B, Hogan QH, Yu H) Gene Ther 2022 Feb;29(1-2):1-15 PMID: 32424233 PMCID: PMC7671947 SCOPUS ID: 2-s2.0-85085190748 05/20/2020       17 Citations
  • Aberrant expression of S-SCAM causes the loss of GABAergic synapses in hippocampal neurons. (Shin SM, Skaar S, Danielson E, Lee SH) Sci Rep 2020 Jan 09;10(1):83 PMID: 31919468 PMCID: PMC6952429 SCOPUS ID: 2-s2.0-85077694386 01/11/2020       12 Citations
  • AAV-encoded CaV2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain. (Yu H, Shin SM, Xiang H, Chao D, Cai Y, Xu H, Khanna R, Pan B, Hogan QH) Gene Ther 2019 Aug;26(7-8):308-323 PMID: 31118475 PMCID: PMC6707887 SCOPUS ID: 2-s2.0-85066867179 05/24/2019       21 Citations
  • Transmembrane protein 100 is expressed in neurons and glia of dorsal root ganglia and is reduced after painful nerve injury. (Yu H, Shin SM, Wang F, Xu H, Xiang H, Cai Y, Itson-Zoske B, Hogan QH) Pain Rep 2019;4(1):e703 PMID: 30801043 PMCID: PMC6370145 SCOPUS ID: 2-s2.0-85061500653 02/26/2019       9 Citations
  • Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes. (Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Heo WD, Kim DW, Yeo CY, Kim CH, Liu QS) Nat Commun 2018 Aug 24;9(1):3434 PMID: 30143647 PMCID: PMC6109165 SCOPUS ID: 2-s2.0-85052238097 08/26/2018       40 Citations
  • Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno-associated virus delivery in adult rats. (Xiang H, Xu H, Fan F, Shin SM, Hogan QH, Yu H) J Neurosci Res 2018 Mar;96(3):436-448 PMID: 28941260 PMCID: PMC5766685 SCOPUS ID: 2-s2.0-85030181311 09/25/2017       10 Citations
  • GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling. (Shin SM, Zhang N, Hansen J, Gerges NZ, Pak DT, Sheng M, Lee SH) Nat Neurosci 2012 Dec;15(12):1655-66 PMID: 23143515 PMCID: PMC3804128 SCOPUS ID: 2-s2.0-84870494059 11/13/2012       106 Citations
  • S-SCAM/MAGI-2 is an essential synaptic scaffolding molecule for the GluA2-containing maintenance pool of AMPA receptors. (Danielson E, Zhang N, Metallo J, Kaleka K, Shin SM, Gerges N, Lee SH) J Neurosci 2012 May 16;32(20):6967-80 PMID: 22593065 PMCID: PMC3365591 SCOPUS ID: 2-s2.0-84861121293 05/18/2012       42 Citations
    • Last update: 12/31/2024