Medical College of Wisconsin
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Ziqing Liu PhD

Ziqing Liu PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Physiology

Member of the Cardiovascular Center

Research Areas of Interest

  • Angiogenesis Modulating Agents
  • Cellular Reprogramming
  • Heart Diseases
  • Myocardial Infarction
  • Myocytes, Cardiac
  • Neovascularization, Physiologic
  • RNA-Binding Proteins
  • Single-Cell Analysis
  • Transcriptome
  • Publications (16)

  • Functional coordination of non-myocytes plays a key role in adult zebrafish heart regeneration. (Ma H, Liu Z, Yang Y, Feng D, Dong Y, Garbutt TA, Hu Z, Wang L, Luan C, Cooper CD, Li Y, Welch JD, Qian L, Liu J) EMBO Rep 2021 Nov 04;22(11):e52901 PMID: 34523214 PMCID: PMC8567231 SCOPUS ID: 2-s2.0-85113185343 09/16/2021       2 Citations
  • Single-Cell RNA Sequencing Reveals Endothelial Cell Transcriptome Heterogeneity Under Homeostatic Laminar Flow. (Liu Z, Ruter DL, Quigley K, Tanke NT, Jiang Y, Bautch VL) Arterioscler Thromb Vasc Biol 2021 Oct;41(10):2575-2584 PMID: 34433297 PMCID: PMC8454496 SCOPUS ID: 2-s2.0-85116134582 08/27/2021       6 Citations
  • SMAD6 transduces endothelial cell flow responses required for blood vessel homeostasis. (Ruter DL, Liu Z, Ngo KM, X S, Marvin A, Buglak DB, Kidder EJ, Bautch VL) Angiogenesis 2021 May;24(2):387-398 PMID: 33779885 PMCID: PMC8206051 SCOPUS ID: 2-s2.0-85103389683 03/30/2021       6 Citations
  • Down-regulation of Beclin1 promotes direct cardiac reprogramming. (Wang L, Ma H, Huang P, Xie Y, Near D, Wang H, Xu J, Yang Y, Xu Y, Garbutt T, Zhou Y, Liu Z, Yin C, Bressan M, Taylor JM, Liu J, Qian L) Sci Transl Med 2020 Oct 21;12(566) PMID: 33087505 PMCID: PMC8188650 SCOPUS ID: 2-s2.0-85094173558 10/23/2020       18 Citations
  • Single-Cell Transcriptomic Analyses of Cell Fate Transitions during Human Cardiac Reprogramming. (Zhou Y, Liu Z, Welch JD, Gao X, Wang L, Garbutt T, Keepers B, Ma H, Prins JF, Shen W, Liu J, Qian L) Cell Stem Cell 2019 Jul 03;25(1):149-164.e9 PMID: 31230860 PMCID: PMC6684137 SCOPUS ID: 2-s2.0-85068031202 06/25/2019       54 Citations
  • Lin28a Regulates Pathological Cardiac Hypertrophic Growth Through Pck2-Mediated Enhancement of Anabolic Synthesis. (Ma H, Yu S, Liu X, Zhang Y, Fakadej T, Liu Z, Yin C, Shen W, Locasale JW, Taylor JM, Qian L, Liu J) Circulation 2019 Apr 02;139(14):1725-1740 PMID: 30636447 PMCID: PMC6443464 SCOPUS ID: 2-s2.0-85064219277 01/15/2019       17 Citations
  • A Loss of Function Screen of Epigenetic Modifiers and Splicing Factors during Early Stage of Cardiac Reprogramming. (Zhou Y, Alimohamadi S, Wang L, Liu Z, Wall JB, Yin C, Liu J, Qian L) Stem Cells Int 2018;2018:3814747 PMID: 29743891 PMCID: PMC5878887 SCOPUS ID: 2-s2.0-85056141313 05/11/2018       13 Citations
  • A loss of function screen of epigenetic modifiers and splicing factors during early stage of cardiac reprogramming (Zhou Y, Alimohamadi S, Wang L, Liu Z, Wall JB, Yin C, Liu J, Qian L) Stem Cells International 2018;2018 SCOPUS ID: 2-s2.0-85056141313 01/01/2018       13 Citations
  • Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte. (Liu Z, Wang L, Welch JD, Ma H, Zhou Y, Vaseghi HR, Yu S, Wall JB, Alimohamadi S, Zheng M, Yin C, Shen W, Prins JF, Liu J, Qian L) Nature 2017 Nov 02;551(7678):100-104 PMID: 29072293 PMCID: PMC5954984 SCOPUS ID: 2-s2.0-85032797966 10/27/2017       111 Citations
  • Comparative Gene Expression Analyses Reveal Distinct Molecular Signatures between Differentially Reprogrammed Cardiomyocytes. (Zhou Y, Wang L, Liu Z, Alimohamadi S, Yin C, Liu J, Qian L) Cell Rep 2017 Sep 26;20(13):3014-3024 PMID: 28954220 PMCID: PMC5659840 SCOPUS ID: 2-s2.0-85029885058 09/28/2017       40 Citations
  • Systematic comparison of 2A peptides for cloning multi-genes in a polycistronic vector. (Liu Z, Chen O, Wall JBJ, Zheng M, Zhou Y, Wang L, Vaseghi HR, Qian L, Liu J) Sci Rep 2017 May 19;7(1):2193 PMID: 28526819 PMCID: PMC5438344 SCOPUS ID: 2-s2.0-85019896240 05/21/2017       232 Citations
  • Re-patterning of H3K27me3, H3K4me3 and DNA methylation during fibroblast conversion into induced cardiomyocytes. (Liu Z, Chen O, Zheng M, Wang L, Zhou Y, Yin C, Liu J, Qian L) Stem Cell Res 2016 Mar;16(2):507-18 PMID: 26957038 PMCID: PMC4828257 SCOPUS ID: 2-s2.0-84959276987 03/10/2016       72 Citations
  • Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming. (Zhou Y, Wang L, Vaseghi HR, Liu Z, Lu R, Alimohamadi S, Yin C, Fu JD, Wang GG, Liu J, Qian L) Cell Stem Cell 2016 Mar 03;18(3):382-95 PMID: 26942853 PMCID: PMC4779178 SCOPUS ID: 2-s2.0-84960112104 03/05/2016       141 Citations
  • Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5. (Wang L, Liu Z, Yin C, Zhou Y, Liu J, Qian L) J Vis Exp 2015 Nov 13(105) PMID: 26649751 PMCID: PMC4692711 SCOPUS ID: 2-s2.0-84949464639 12/10/2015       24 Citations
  • Improved generation of induced cardiomyocytes using a polycistronic construct expressing optimal ratio of Gata4, Mef2c And Tbx5 (Wang L, Liu Z, Yin C, Zhou Y, Liu J, Qian L) Journal of Visualized Experiments 13 November 2015;2015(105) SCOPUS ID: 2-s2.0-84949464639 11/13/2015       24 Citations
  • Stoichiometry of Gata4, Mef2c, and Tbx5 influences the efficiency and quality of induced cardiac myocyte reprogramming. (Wang L, Liu Z, Yin C, Asfour H, Chen O, Li Y, Bursac N, Liu J, Qian L) Circ Res 2015 Jan 16;116(2):237-44 PMID: 25416133 PMCID: PMC4299697 SCOPUS ID: 2-s2.0-84922105989 11/25/2014       149 Citations
  • Last update: 11/08/2022