Date of Document: March 29, 2024
CURRICULUM VITAE

Michele Ann Frommelt MD
Adjunct Professor
Department of Pediatrics
Division of Cardiology

OFFICE ADDRESS:
Children’s Wisconsin - Milwaukee Hospital
8915 W Connell Court
Milwaukee, WI 53226

EDUCATION:
08/1976 - 06/1980 BS, State University of New York, Binghamtom, NY
08/1980 - 06/1984 MD, State University of New York at Downstate, Brooklyn, NY

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
06/1984 - 06/1987 Resident, Pediatrics, Columbia Presbyterian Medical Center, New York, NY
07/1987 - 06/1988 Fellowship, Pediatric Allergy and Immunology, Texas Children’s Hospital, Houston, TX
07/1988 - 06/1991 Fellowship, Pediatric Cardiology, University of Michigan Medical Center, C.S. Mott Children’s Hospital, Ann Arbor, MI

FACULTY APPOINTMENTS:
07/1991 - 2002 Assistant Professor, Department of Pediatrics, Division of Pediatric Cardiology, Medical College of Wisconsin, Milwaukee, WI
07/2002 - Present Associate Professor, Department of Pediatrics, Division of Pediatric Cardiology, Medical College of Wisconsin, Milwaukee, WI
07/2013 - Present Professor, Department of Pediatrics, Division of Pediatric Cardiology, Medical College of Wisconsin, 8701 W Watertown Pland Rd, Milwaukee, WI 53226

ADMINISTRATIVE APPOINTMENTS:
08/1991 - Present Co-director, Pediatric Echocardiography, Children’s Hospital of Wisconsin, 9000 W Wisconsin Ave, Milwaukee, WI 53226
01/2004 - Present Director, Fetal Cardiac Program, Children’s Hospital of Wisconsin, 9000 W Wisconsin Ave, Milwaukee, WI 53226
01/2010 - Present Director, Pediatric Cardiology Nurse Practitioner Program, Medical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226

HOSPITAL STAFF PRIVILEGES:
09/1991 - Present Froedtert Memorial Lutheran Hospital, 9200 W Wisconsin Ave, Milwaukee, WI 53226
09/1991 - Present Children’s Hospital of Wisconsin, 9000 W. Wisconsin Ave., Milwaukee, WI 53226
01/1997 - Present Waukesha Memorial Hospital, 725 American Ave, Waukesha, WI 53188
05/1998 - Present St Joseph’s Hospital, 5000 W Chambers Ave, Milwaukee, WI 53210
05/1998 - Present Sinai Samaritan Medical Center, 945 North 12th St, Milwaukee, WI 53201
05/1998 - Present West Allis Memorial Hospital, 8901 W Lincoln Ave, Milwaukee, WI 53227
05/1999 - Present Columbia/St Mary’s Hospital, 2323 N Lake Dr, Milwaukee, WI 53211

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
National Board of Medical Examiners
1985
1985
American Board of Pediatrics
1988
1988
American Board of Pediatrics, Cardiology
1991
1991
American Board of Pediatrics, Cardiology
1998
1998
   
Licensure
Number Issue DateExpiration
New York License
1984
1987
Michigan License
1988
1991
Wisconsin License
#32419
1991
None
Illinois License
1998
2014
    

AWARDS AND HONORS:
1979 Phi Beta Kappa
1983 Phi Beta Kappa
2000 - Present Best Doctors in America

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1990 American College of Cardiology (Affiliate in Training)
1990 Michigan Society of Echocardiography (Member)
1990 - Present Society of Pediatric Echocardiography (Member)
1991 - Present American Society of Echocardiography (Member)
1991 - Present American Heart Association (Council of Cardiovascular Disease in the Young)
1996 - Present Midwest Pediatric Cardiology Society (Member)
2001 - Present American College of Cardiology (Fellow)
2015 - 2019 Make-A-Wish (Member, Advisory Board)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
1997 Journal of the American Society of Echocardiography
1998 American Journal of Cardiology
2010 Echocardiography

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
1993 Member, Medical Records committee, Children’s Hospital of Wisconsin
2002 Member, Continuing Medical Education Committee, Medical College of Wisconsin
2011 Co-Physician Leader, Fetal Concerns Center of Wisconsin, Children’s Hospital of Wisconsin

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2008 - 2010 Member, See My Heart, American Society of Echocardiography

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Trial of ACE inhibition in infants with single ventricle
Source:
Pediatric Heart Network/National Heart, Lung and Blood Institute
Role:
Co-investigator
Dates:
2004 - Present
  
Title:
Single Ventricle Reconstruction Trial – 2D Core Echo Lab
Source:
Pediatric Heart Network/National Heart, Lung and Blood Institute
Role:
Co-investigator
Dates:
2005 - Present
  
Title:
National Pediatric Cardiology Quality Initiative Collaborative
Source:
Joint Council on Congenital Heart Disease
Role:
Co-investigator
Dates:
2009 - Present
  
Title:
PHN Pediatric Echo Z-Score Project
Source:
Pediatric Heart Network
Role:
Principal Investigator
Dates:
08/01/2014 - Present
  
Title:
Long-term Outcomes of Children with HLHS and the Impact of Norwood Shunt Procedure (SVRIII)
Source:
Pediatric Heart Network
Role:
Principal Investigator
Dates:
11/01/2015 - Present
  
Title:
Test of Methods to Assess Maternal Working Models of Parenting
Source:
UW Madison School of Nursing, CHW IRB 238
Role:
Key personnel
  
Title:
Pre-Post Natal Coping
Source:
CHW IRB 69
Role:
Principal Investigator
PI:
Self
  
Title:
Mobile Fetal Magnetocardiography
Source:
University of Wisconsin 2011-0169
Role:
Consultant MCW, referring physician
  
Title:
Parenting After Infant Congenital Heart Defect Diagnosis
Source:
American Nurses Foundation, CHW IRB 42
Role:
Key personnel
  
Title:
The kinetics of ventricular dysfunction in the single ventricle population
Source:
CHW IRB 159
Role:
Co-investigator
  
Title:
Late anatomic and myocardial assessment of anomalous origin of a coronary artery from the opposite sinus following surgical unroofing
Source:
CHW IRB 67
Role:
Co-investigator
  
Title:
Leftward displacement of septum primum in hypoplastic left heart syndrome
Source:
CHW IRB 302
Role:
Co-investigator
  
Title:
Magnetic Recording of Fetal Heart Activity
Source:
University of Wisconsin 2007-0140
Role:
Consultant MCW, referring physician
  
Title:
Simultaneous Fetal Echocardiography and Magnetocardiography
Source:
University of Wisconsin 2006-0381
Role:
Consultant MCW, referring physician
  
Title:
The bidirectional cavopulmonary shunt and completion Fontan in young patients with heterotaxy and interrupted inferior vena cava
Source:
CHW IRB 65
Role:
Prinicipal Investigator
PI:
Self
  

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Cardiology Rounds Presentation: “Echocardiographic Segmental Approach to Congenital Heart Disease”, Sinai Samaritan Medical Center, 01/1992
Cardiology Rounds Presentations: “Show and Tell-Pediatric Echocardiography”, Sinai Samaritan Medical Center, 10/1992
Grand Rounds Presentations: “Primary Pulmonary Hypertension”, Children’s Hospital of Wisconsin, 10/1992
Faculty, “Common Problems in Pediatrics”, CME Program, Children’s Hospital of Wisconsin, 11/1992
Seminar: “Fetal Echocardiography”, St Vincent Hospital, Green Bay, WI, 11/1993
Ground Round Presentation: “Fetal Echocardiography”, St Joseph’s Hospital, Milwaukee, WI, 01/1994
Faculty, “The Heart of Cardiology is Still Echocardiography”, Sinai Samaritan Medical Center, Milwaukee, WI, 04/1994
Grand Rounds Presentation: “Fetal Echocardiography”, Children’s Hospital of Wisconsin, 05/1997
Congenital Heart Disease and the Community Physician, Children’s Hospital of WI, Milwaukee, WI, 10/2001
Faculty, Perinatal Conference, Theda Clark, Neenah, WI, 11/2001
Fetal Cardiac Disease, St. Joseph’s Hospital Maternal Fetal Medicine Grand Rounds, 10/2006
Supraventricular Tachycardia, Elmbrook Hospital Maternal Fetal Medicine Conference, 03/2008
The Fetal Cardiac Patient, CRI March of Dimes Research Conference, Children’s Hospital of Wisconsin, 04/2009
The Fetal Cardiac Patient: A Real Entity, The Healthy Babies Summit and AWHONN State Conference, Waukesha, WI, 10/2009
Assessment of the Single Ventricle, Froedtert Memorial Maternal Fetal Medicine Conference, 09/2010
 
Regional
Faculty, “Dynamics of Cardiac Ultrasound Seminar”, Minneapolis, MN, 12/1992
Grand Rounds Presentation: “Fetal Echocardiography”, St Therese Medical Center, Waukegan, IL, 05/1998
Grand Round Presentation: “Heart Murmurs”, St Theresa Medical Center, Waukegan, IL, 05/2000
Grand Round Presentations: “Syncope”, St Theresa Medical Center, Waukegan, IL, 06/2001
Faculty and Lecturer: “Fetal Arrhythmias”, Pediatric Cardiology 2008 Board Review Course, Rochester, MN, 10/2008
Faculty and Lecturer: “Evaluating the Fetus with Congenital Heart Disease”., Pediatric Cardiology 2008 Board Review Course, Rochester, MN, 10/2008
 
National
Faculty and Invited Lecturer: “Fetal Evaluation of Hypoplastic Left Heart.” Scientific Sessions Program, American Society of Echocardiography National, 06/1998
Faculty and Invited Lecturer: “Case Studies: Read with the Experts.” Scientific Sessions Program, American Society of Echocardiography National Meeting, 06/1999
Faculty and Invited Lecturer: “Controversies in Congenital Heart Disease: AV Valve Regurgitation Should Not Be Quantified.” Scientific Sessions Program, American Society of Echocardiography National Meeting, 06/2000
Faculty and Invited Lecturer: “Parental Response to the Abnormal Fetal Exam.” Scientific Sessions Program, American Society of Echocardiography National Meeting, 06/2000
Faculty and Invited Lecturer: “Case Studies: Read with the Experts.” Scientific Sessions Program, American Society of Echocardiography National Meeting, 06/2000
Faculty and Invited Lecturer: “Fetal Arrhytmias: Detection, Characterization, and Management”., American College of Cardiology National Meeting, New Orleans, LA, 03/2004
Faculty and Invited Lecturer: “Aberrant Coronary Artery Proximal Course and Myocardial Bridging: Diagnosis and Management.” Scientific Sessions Program, American Heart Association National Meeting, 11/2006
Faculty and Invited Lecturer: “Starting from Scratch: Challenges and Successes in Instituting a Regional Program in Wisconsin”., Cardiology 2007, Tenth Annual Update on Pediatric Cardiovascular Disease:, Lake Buena Vista, FL, 02/2007
Faculty and Invited Lecturer: “Echocardiography 2007-My Most Interesting Case”. Cardiology 2007, Tenth Annual Update on Pediatric Cardiovascular Disease, Lake Buena Vista, FL, 02/2007
Faculty And Invited Lecturer: “Echocardiographic Assessment of Ventricular Septal Defects and Associated Lesions”., ”. Cardiology 2007, Tenth Annual Update on Pediatric Cardiovascular Disease, Lake Buena Vista, FL, 02/2007
Faculty and Invited Lecturer: “Imaging the Coronary Arteries.” Cardiology 2007, Tenth Annual Update on Pediatric Cardiovascular Disease, Lake Buena Vista, FL, 02/2007
Faculty and Invited Lecturer: “Congenital Coronary Artery Anomalies Predisposing to Sudden Cardiac Death”., Michael H. Ludwig Foundation Lectureship, Mount Sinai Hospital, New York, 04/2008
Faculty and Lecturer: “Essential Components of the Normal Fetal Echocardiogram: What is the Standard of Care in 2009”, American Society of Echocardiography National Meeting, Washington, DC, 2009
Faculty and Invited Lecturer: “Assessment of Coronary Artery Abnormalities by Echo/CT/MRI.”, Cardiology 2010, Thirteenth Annual Update on Pediatric Cardiovascular Disease, Lake Buena Vista, FL, 02/2010
Faculty and Invited Lecturer: “The Normal Anatomy and Segmental Approach to Imaging.”, Cardiology 2010, Thirteenth Annual Update on Pediatric Cardiovascular Disease, Lake Buena Vista, FL, 02/2010
Faculty and Invited Lecturer: “Impact of Prenatal Diagnosis on the Family.” Cardiology 2010, Thirteenth Annual Update on Pediatric Cardiovascular Disease, Lake Buena Vista, FL, 02/2010
Faculty and Invited Lecturer: “Assessment of the Fetal Left Ventricle”, American College of Cardiology National Meeting, Atlanta, GA, 03/2010
Faculty and Invited Moderator: "Challenges in Detection of Congenital Heart Disease by Fetal Echocardiography", American Heart Association National Meeting, Scientific Sessions, Chicago, Illinois, 11/2014
Faculty and Invited Moderator: "Mom, Dad and Baby: Pregnancy and Congenital Heart Disease-Optimizing Outcomes through Case Discussion", American College of Cardiology National Meeting, Scientific Sessions, San Diego, California, 03/2015
Faculty and Invited Lecturer: "The Many Faces of Ischemia and Infarct in Pediatric and Congenital Heart Disease-Inflammatory/Infectious", American Society of Echocardiography National Meeting, Scientific Sessions, Boston, Massachusetts, 06/2015
Faculty and Moderator: "Debates and Discussion", American Society of Echocardiography National Meetings, Nashville, Tennessee, 06/2017
Faculty and Invited Lecturer:"Case Competition: Umbilical Venous Pulsations Associated with a benign arrhythmia, American Society of Echocardiography National Meetings, Nashville, Tennessee, 06/2018
Faculty and Invited Lecturer: "Diagnostic Dilemmas and Exercise Restrictions in Congenital Heart Disease", American College of Cardiology Scientific Session, Washington DC, - 03/2014
 
International
Faculty and invited lecturer, “Management of Fetal Arrhythmias, What’s New?”., American Society of Echocardiography National Meeting, Montreal, Canada, 2011
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
1991 - Present Lecturer, Core Pediatric lecture series to third year medical students
1991 - 1995 Faculty, Gross Anatomy (laboratory on congenital cardiovascular anomalies)
1992 - Present Faculty, Human Development Course (Anatomy 152)
 
Resident and Fellow Education
2004 - Present Lecturer, weekly Pediatric Cardiology Core Curriculum Lecture Series
2004 - Present Director, daily Pediatric Cardiology Fellow Review Teaching Session
 

EXTRAMURAL TEACHING:
Community/Lay Public
02/2004 - Present Children’s Hospital of Wisconsin, Lecturer, Parent Education Day
 
Medical Student Education
1992 - Present Children’s Hospital of Wisconsin, Teaching Ward Attending
 
Resident and Fellow Education
1991 - Present Children’s Hospital of Wisconsin, Co-director and lecturer, Daily Pediatric Echocardiography Studies Review
1992 - Present Children’s Hospital of Wisconsin, Lecturer, Pediatric Housestaff Noon Conference
1994 - Present Medical College of Wisconsin, Adult Cardiology/Medicine Division, Invited lecturer on varying topics in congenital heart disease, Adult Echocardiography Conference
1996 - 2000 Children’s Hospital of Wisconsin, Co-director and lecturer, Pediatric Echocardiography mini-fellowship for sonographers and physicians
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Peggy Lovejoy, Medical College of Wisconsin, 1996 Co-preceptor, 4th year medical student research project in pediatric cardiology
Kurt Isenberger, Medical College of Wisconsin, 1998 Co-preceptor, 2nd year medical student summer extern research project in pediatric cardiology
Jean Ballweg, Medical College of Wisconsin, 1999 - 2001 Co-preceptor, pediatric resident project for a career in pediatric cardiology
David Sheridan, Medical College of Wisconsin, 2005 - 2007 Co-preceptor, medical student project in pediatric cardiology
 
Clinical/Research Fellows
Beth Ann Johnson, Medical College of Wisconsin, 06/30/2007
Matthew Brown, Medical College of Wisconsin, 06/30/2008
Shelby Kutty, Medical College of Wisconsin, 06/30/2008
David Saudek, Medical College of Wisconsin, 06/30/2008
Rohit Rao, Medical College of Wisconsin, 06/30/2008
Matthew Park, Medical College of Wisconsin, 06/30/2008
Anas Salkini, Medical College of Wisconsin, 06/30/2009
Jennifer Co-Vu, Medical College of Wisconsin, 06/30/2009
Elena Kwon, Medical College of Wisconsin, 06/30/2010
Suneetha Venkatapuram, Medical College of Wisconsin, 06/30/2010
Alicia Chaves, Medical College of Wisconsin, 06/30/2011
Joshua Kovach, Medical College of Wisconsin, 06/30/2011
Chesney Castleberry, Medical College of Wisconsin, 06/30/2011
Catherine Weinberg, Medical College of Wisconsin, 08/31/2011
Shanelle Clarke, Medical College of Wisconsin, 06/30/2012
Joseph Camarda, Medical College of Wisconsin, 06/30/2012
Salil Ginde, Medical College of Wisconsin, 06/30/2012
Scott Cohen, Medical College of Wisconsin, 06/30/2012
Jennifer Plymale, Medical College of Wisconsin, 06/30/2012
Garick Hill, Medical College of Wisconsin, 06/30/2013
Jonathan Cramer, Medical College of Wisconsin, 06/30/2013
Daniel Cox, Medical College of Wisconsin, 06/30/2014
Melissa Smith, Medical College of Wisconsin, 06/30/2014
Joseph Block, Medical College of Wisconsin, 06/30/2014
Pip Hidestrand, Medical College of Wisconsin, 08/31/2015
 

PROGRAMMATIC DEVELOPMENTS:
Educational Programs
Faculty
1991 - Present Initiated and developed the fetal echocardiography program at Children’s Hospital of Wisconsin, providing extensive fetal cardiac imaging training
 
Research Programs
1991 - Present Developed a state-of-the-art academic pediatric echocardiography laboratory with local, regional, and national recognition as a premier site for pediatric cardiac imaging
 
Clinical Programs
2010 - Present Director of the pediatric cardiology nurse practioner program at the Medical College of Wisconsin
 
Community Programs
2000 - Present Developed and staffed, with Nancy Ghanayem, MD, the Interstage Surveillance Program, a home monitoring system for high-risk patients with shunt-dependent pulmonary blood flow
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Meliones J, Snider AR, Beekman R, Bengur AR, Bogaards M. Echocardiographic detection of pericardiocentesis-induced subepicardial and intramyocardial hematoma. Am J Cardiol 64:820-821, 1989.
2. Frommelt MA, Snider AR, Crowley DC, Meliones JN, Heidelberger KP. Echocardiographic indexes of allograft rejection in pediatric cardiac transplant recipients. J Am Soc Echocardiogr 5:41-47, 1992.
3. Frommelt MA, Snider AR, Bove EL, Lupinetti FM. Echocardiographic assessment of Subvalvular aortic stenosis pre- and post-operatively. J Am Coll Card 195(5):1018-1023, 1992.
4. Frommelt MA, Frommelt PC, Berger S, Pelech AN, Lewis DA, Tweddell JS, Litwin SB. Does an additional source of pulmonary blood flow alter outcome after a bidirectional cavoplumonary shunt? Circulation 92II: 240-4, 1995.
5. Tweddell JS, Berger S, Frommelt PC, Pelech AN, Lewis DA, Fedderly RT, Frommelt MA, McManus TS, Mussato KA, Kessel MW, Litwin SB. Aprotinin improves outcome of single-ventricle palliation. Annals of Thoracic Surgery 62(5):1329-35; discussion 1335-6, 1996.
6. Tweddell JS, Litwin SB, Berger S, Friedberg DZ, Thomas JP, Frommelt PC, Frommelt MA, Pelech AN, Lewis DA, Fedderly RT, Mussatto KA, Kessel MW. Twenty-year experience with repair of complete artrioventricular septal defects. Annuals of Thoracic Surgery 62(2): 419-24, 1996.
7. Fedderly RT, Berger S, Frommelt PC, Lewis DA, Dhala A, Pelech AN, Frommelt MA, Friedberg DZ, Thomas JP, Tweddell JS, Litwin SB. Advances in the care of children with heart disease. Wisconsin Medical Journal, 47-50, 1998.
8. Frommelt PC, Friedberg DZ, Frommelt MA, Williamson JG. Anomalous origin of the right coronary artery from the left sinus of Valsalva: Transthoracic echo diagnosis. J Am Soc Echocardiogr 12: 221-4, 1999.
9. Tweddell JS, Pelech AN, Frommelt PC, Mussatto KA, Wyman JD, Fedderly RT, Berger S, Frommelt MA, Lewis DA, Friedberg DZ Thomas JP, Litwin SB. Factors affecting the longevity of homograft valves utilized in right ventricular outflow tract reconstruction for congenital heart disease. Circulation 102:130-135, 2000.
10. Frommelt MA, Miller ME, Williamson J, Bergstrom S. Detection of septal coronary collaterals by Doppler color flow mapping is a marker for anomalous origin of a coronary artery from the pulmonary artery. J Am Soc Echocardiogr, 15: 259-263, 2002.
11. Frommelt PC, Whitstone EN, Frommelt MA. Experience with a DICOM-compatible digital pediatric echocardiographic laboratory. Pediatric Cardiology, 23: 53-57, 2002.
12. Frommelt PC, Ballweg JA, Whitstone EN, Frommelt MA. Usefulness of Doppler tissue imaging analysis of tricuspid annular motion for determination of right ventricular function in normal infants and children. Am J Cardiol, 89: 610-613, 2002.
13. Leuthner SR, Bolger M, Frommelt MA, Nelson R. The impact of abnormal fetal echocardiography on expectant parents' experience of pregnancy: a pilot study. J Psychosom Obstet Gynaecol 24: 121-129, 2003.
14. Frommelt PC, Pelech AN, Frommelt MA. Diastolic dysfunction in an unusual case of cardiomyopathy in a child- insights from Doppler and Doppler tissue imaging. J Am Soc Echocardiogr 16: 176-181, 2003.
15. Frommelt PC, Frommelt MA, Jaquiss RDB, Tweddell JS. Prospective echo diagnosis and surgical repair of anomalous origin of a coronary artery (AOCA) from the opposite sinus with an intersrterial course. J Am Coll Cardiol 42: 148-154, 2003.
16. Frommelt PC, Sheridan DC, Mussatto KA, Hoffman GM, Ghanayem NS, Frommelt MA, Tweddell JS. Effect of shunt type on echo indices after initial palliation for hypoplastic left heart syndrome: BT shunt vs. RV-PA conduit. J Am Soc Echocardiogr 19: 1364-1373, 2007.
17. Ohye RG, Gaynor JW, Ghanayem NS, Goldberg CS, Laussen PC, Frommelt PC, Newburger JW, Pearson GD, Tabbutt S, Wernovsky G, Wruck LM, Atz AM, Colan SD, Jaggers J, McCrindle BW, Prakash A, Puchalski MJ, Sleeper LA, Stylianou MP, Mahony L, Pediatric Heart Network Investigators. Design and rationale of a randomized trial comparing the Blalock-Taussig and right ventricle-pulmonary artery shunts in the Norwood procedure. J Thorac Cardiovasc Surg 136: 968-975, 2008.
18. Frommelt PC, Gorentz J, Deatsman S, Organ D, Frommelt MA, Mussato K. Digital imaging, archiving, and structured reporting in pediatric echocardiography: impact on laboratory efficiency and physician communication. J Am Soc Echocardiogr 21: 935-940, 2008.
19. Hsu DT, Mital S, Ravishankar C, Margossian R, Li JS, Sleeper LA, Williams RV, Levine JC, McCrindle BW, Atz AM, Servedio D, Mahony L; Pediatric Heart Network Investigators. Rationale and design of a trial of angiotensin-converting enzyme inhibition in infants with single ventricle. Am Heart J 157: 37-45, 2009.
20. Peterson AL, Deatsman S, Frommelt MA, Mussatto KA, Frommelt PC. Correlation of echocardiographic markers and therapy in persistent pulmonary hypertension of the newborn. Pediatr Cardiol 30(2):160-165, 2009.
21. Kutty S, Cava JR, Frommelt MA. Idiopathic infantile arterial calcification: a case report of prenatal and postnatal echocardiographic diagnosis. Echocardiography 26: 862-864, 2009.
22. Ghanayem NS, Hoffman GM, Mussato KA, Frommelt MA, Cave JR, Mitchell ME, Tweddell JS. Perioperative monitoring in high-risk infants after stage 1 palliation of univentricular congenital heart disease. J Thorac Cardiovasc Surg 140: 857-863, 2010.
23. Kutty S, Frommelt MA, Danford DA, Tweddell JS. Medium-term outcomes of kawashima and completion fontan palliation in single-ventricle heaert disease with heterotaxy and interrupted inferior vena cava. Ann Thorac Surg 90: 1609-13, 2010.
24. Hsu DT, Zak V, Mahony L, Sleeper LA, Atz AM, Levine JC, Barker PC, Ravishankar C, McCrindle BW, Williams RV, Altmann K, Ghanayem NS, Margossian R, Chung WK, Border WL, Pearson GD, Stylianou MP, Mital S; Pediatric Heart Network Investigators. Enalapril in infants with single ventricle: results of a multicenter randomized trial. Circulation 122: 333-340, 2010.
25. Atz AM, Trasvison TG, Williams IA, Pearson GD, Laussen PC, Mahle WT, Cook AL, Kirsh JA, Sklandsky M, Khaikin S, Goldberg C, Frommelt MA, Krawczeski C, Puchalski MD, Jacobs JP, Baffa JM, Rychik J, Ohye RG, Pediatric Network Investigators. Prenatal diagnosis and risk factors for preoperative death in neonates with single right ventricular and systemic outflow obstruction: Screening data from the pediatric heart network single ventricular reconstruction trial*. J Thorac Cardiovasc Surg 140: 1245-50, 2010.
26. Frommelt P, Sheridan D, Deatsman S, Yan K, Simpson P, Frommelt MA, Litwin SB, Tweddell JS. Unobstructive total anomalous pulmonary venous return: impact of early elective repair on the need for prolonged mechanical ventilatory support. Pediatr Cardiol 16:1-7, 2010
27. Camarda JA, Russell DS, Frommelt MA. Persistent fifth aortic arch: echocardiographic diagnosis of a persistent fifth aortic arch. Echocardiography 28: E44-5, 2011.
28. Frommelt PC, Sheridan DC, Berger S, Frommelt MA, Tweddell JS. Ten-year experience with surgical unroofing of anomalous origin of a coronary artery from the opposite sinus with an interarterial course. J Thorac Cardiovasc Surg 2011 Mar 23 (Epub ahead of print).
29. Mital S, Chung WK, Colan SD, Sleeper LA, Manlhiot C, Arrington CB, Cnota JF, Graham EM, Mitchell ME, Goldmuntz E, Li JS, Levine JC, Lee TM, Margossian R, Hsu DT; Pediatric Heart Network Investigators. Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle. Circulation 123: 2353-2362, 2011.
30. Hehir DA, Rudd N, Slicker J, Mussatto KA, Simpson P, Li SH, Frommelt MA, Tweddell JS, Ghanayem NS. Normal interstage growth after the norwood operation associated with interstage home monitoring. Pediatr Cardiol. 2012 Dec;33(8):1315-22. PMCID: PMC4787622
31. Camarda JA, Harris SE, Hambrook J, Frommelt MA, Tweddell JS, Frommelt PC. Abnormal mitral valve anatomy in d-transposition of the great arteries: anatomic characterization and surgical outcomes. Pediatr Cardiol. 2013 Jan;34(1):70-4.
32. Park MV, Fedderly RT, Frommelt PC, Frommelt MA, Pelech AN, Jaquiss RD, Mussatto K, Tweddell JS. Leftward displacement of septum primum in hypoplastic left heart syndrome. Pediatr Cardiol. 2013 Apr;34(4):942-7. PMCID: PMC4567036
33. Hill GD, Hehir DA, Bartz PJ, Rudd NA, Frommelt MA, Slicker J, Tanem J, Frontier K, Xiang Q, Wang T, Tweddell JS, Ghanayem NS. Effect of feeding modality on interstage growth after stage I palliation: a report from the National Pediatric Cardiology Quality Improvement Collaborative. J Thorac Cardiovasc Surg. 2014 Oct;148(4):1534-9. PMCID: PMC4126898
34. Rudd NA, Frommelt MA, Tweddell JS, Hehir DA, Mussatto KA, Frontier KD, Slicker JA, Bartz PJ, Ghanayem NS. Improving interstage survival after Norwood operation: outcomes from 10 years of home monitoring. J Thorac Cardiovasc Surg. 2014 Oct;148(4):1540-7.
35. Niebler RA, Ghanayem NS, Shah TK, De La Rosa Bobke A, Zangwill S, Brosig C, Frommelt MA, Mitchell ME, Tweddell JS, Woods RK. Use of a HeartWare ventricular assist device in a patient with failed Fontan circulation. Ann Thorac Surg. 2014 Apr;97(4):e115-6.
36. Loomba RS, Frommelt M, Moe D, Shillingford AJ. Agenesis of the venous duct: two cases of extrahepatic drainage of the umbilical vein and extrahepatic portosystemic shunt with a review of the literature. Cardiol Young; May 2014: 1-10 [Epub ahead of print]
37. Frommelt MA. Challenges and controversies in fetal diagnosis and treatment: hypoplastic left heart syndrome. Clin Perinatol. 2014 Dec;41(4):787-98.
38. Hill GD, Block JR, Tanem JB, Frommelt MA. Disparities in the prenatal detection of critical congenital heart disease. Prenat Diagn. 2015 Sep;35(9):859-63. PMCID: PMC4558244
39. Johnson JT, Sleeper LA, Chen S, Ohye RG, Gaies MG, Williams IA, Sachdeva R, Pruetz JD, Tatum GH, Thacker D, Brunetti MA, Frommelt MA, Jacobs JP, Kirsh JA, Lambert LM, Newburger JW, Pemberton VL, Zyblewski SC, Divanovic AA, Pinto NM, Pediatric Heart Network Investigators. Associations Between Day of Admission and Day of Surgery on Outcome and Resource Utilization in Infants With Hypoplastic Left Heart Syndrome Who Underwent Stage I Palliation (from the Single Ventricle Reconstruction Trial). Am J Cardiol. 2015 Oct 15;116(8):1263-9. PMCID: PMC4589492
40. Moon-Grady AJ, Morris SA, Belfort M, Chmait R, Dangel J, Devlieger R, Emery S, Frommelt M, Galindo A, Gelehrter S, Gembruch U, Grinenco S, Habli M, Herberg U, Jaeggi E, Kilby M, Kontopoulos E, Marantz P, Miller O, Otaño L, Pedra C, Pedra S, Pruetz J, Quintero R, Ryan G, Sharland G, Simpson J, Vlastos E, Tworetzky W, Wilkins-Haug L, Oepkes D, International Fetal Cardiac Intervention Registry. International Fetal Cardiac Intervention Registry: A Worldwide Collaborative Description and Preliminary Outcomes. J Am Coll Cardiol. 2015 Jul 28;66(4):388-99.
41. Zak V, Hsu DT, Pemberton VL, Levine JC, Atz AM, Cnota JF, Ravishankar C, Barker P, Lambert LM, McCrindle BW, Frommelt MA, Altmann K, Chen S, Williams RV, Pediatric Heart Network Investigators. Translating clinical trials into clinical practice: a survey assessing the potential impact of the Pediatric Heart Network Infant Single Ventricle Trial. Cardiol Young. 2017 Sep;27(7):1265-1270. PMCID: PMC5721352
42. Brothers JA, Frommelt MA, Jaquiss RDB, Myerburg RJ, Fraser CD Jr, Tweddell JS. Expert consensus guidelines: Anomalous aortic origin of a coronary artery. J Thorac Cardiovasc Surg. 2017 Jun;153(6):1440-1457.
43. Patel SG, Frommelt MA, Frommelt PC, Kutty S, Cramer JW. Echocardiographic Diagnosis, Surgical Treatment, and Outcomes of Anomalous Left Coronary Artery from the Pulmonary Artery. J Am Soc Echocardiogr. 2017 Sep;30(9):896-903.
44. Ahmed M, Thompson NE, Foerster SR, Frommelt MA, Mitchell ME, Scott JP. Ventricular Fibrillation and Myocardial Depression Following Pulmonary Valve Replacement in Tetralogy of Fallot With an Intramural Coronary Artery and Coronary Artery Compression by Chest Tube. World J Pediatr Congenit Heart Surg. 2020 Jul;11(4):NP77-NP79.
45. Hill GD, Kovach JR, Saudek DE, Singh AK, Wehrheim K, Frommelt MA. Transplacental treatment of fetal tachycardia: A systematic review and meta-analysis. Prenat Diagn. 2017 Nov;37(11):1076-1083.
46. Hraska V, Mitchell ME, Woods RK, Frommelt MA. What surgical improvements are needed to prove that anatomic repair is superior to physiologic repair in the majority of patients with corrected transposition of the great arteries? J Thorac Cardiovasc Surg. 2017 Sep;154(3):1019-1022.
47. Cramer JW, Kutty S, Patel SG, Frommelt MA, Frommelt PC. Authors' Reply. J Am Soc Echocardiogr. 2018 Jan;31(1):114.
48. Sachdeva S, Frommelt MA, Mitchell ME, Tweddell JS, Frommelt PC. Surgical unroofing of intramural anomalous aortic origin of a coronary artery in pediatric patients: Single-center perspective. J Thorac Cardiovasc Surg. 2018 Apr;155(4):1760-1768.
49. Frommelt PC, Minich LL, Trachtenberg FL, Altmann K, Camarda J, Cohen MS, Colan SD, Dragulescu A, Frommelt MA, Johnson TR, Kovalchin JP, Lin L, Mahgerefteh J, Nutting A, Parra DA, Pearson GD, Pignatelli R, Sachdeva R, Soriano BD, Spurney C, Srivastava S, Statile CJ, Stelter J, Stylianou M, Thankavel PP, Tierney ES, van der Velde ME, Lopez L, Pediatric Heart Network Investigators. Challenges With Left Ventricular Functional Parameters: The Pediatric Heart Network Normal Echocardiogram Database. J Am Soc Echocardiogr. 2019 Oct;32(10):1331-1338.e1. PMCID: PMC6779514
50. Tanem J, Rudd N, Rauscher J, Scott A, Frommelt MA, Hill GD. Survival After Norwood Procedure in High-Risk Patients. Ann Thorac Surg. 2020 Mar;109(3):828-833.
51. Samudrala SSK, North LM, Stamm KD, Earing MG, Frommelt MA, Willes R, Tripathi S, Dsouza NR, Zimmermann MT, Mahnke DK, Liang HL, Lund M, Lin CW, Geddes GC, Mitchell ME, Tomita-Mitchell A. Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction. Mol Genet Genomic Med. 2020 Apr;8(4):e1152. PMCID: PMC7196453
52. Spearman AD, Ginde S, Goot BH, Schaal AM, Feng M, Pan AY, Frommelt MA, Frommelt PC. Echocardiographic Identification of Pulmonary Artery Flow Reversal: An Indicator of Adverse Outcomes in Single Ventricle Physiology. Pediatr Cardiol. 2020 Dec;41(8):1632-1638.
53. Lopez L, Frommelt PC, Colan SD, Trachtenberg FL, Gongwer R, Stylianou M, Bhat A, Burns KM, Cohen MS, Dragulescu A, Freud LR, Frommelt MA, Lytrivi ID, Mahgerefteh J, McCrindle BW, Pignatelli R, Prakash A, Sachdeva R, Soslow JH, Spurney C, Taylor CL, Thankavel PP, Thorsson T, Tretter JT, Young LT, LuAnn Minich L, Pediatric Heart Network Investigators. Pediatric Heart Network Echocardiographic Z Scores: Comparison with Other Published Models. J Am Soc Echocardiogr. 2021 Feb;34(2):185-192. PMCID: PMC7870534
54. Van Galder H, Schaal AM, Feng M, Pan AY, Frommelt MA, Ginde S, Spearman AD. Increases in oxygen saturation following discharge from Fontan palliation - an indicator of resolution of pulmonary arteriovenous malformations? Cardiol Young. 2021 Nov;31(11):1807-1813.
55. Thareja SK, Frommelt MA, Lincoln J, Lough JW, Mitchell ME, Tomita-Mitchell A. A Systematic Review of Ebstein's Anomaly with Left Ventricular Noncompaction. J Cardiovasc Dev Dis. 2022 Apr 13;9(4). PMCID: PMC9031964
56. Handler SS, Chan T, Ghanayem NS, Rudd N, Wright G, Visotcky A, Sparapani R, Mitchell ME, Hoffman GM, Frommelt MA. Impact of Reintervention During Stage 1 Palliation Hospitalization: A National, Multicenter Study. Ann Thorac Surg. 2023 Apr;115(4):975-981.
57. Thareja SK, Anfinson M, Cavanaugh M, Kim MS, Lamberton P, Radandt J, Brown R, Liang HL, Stamm K, Afzal MZ, Strande J, Frommelt MA, Lough JW, Fitts RH, Mitchell ME, Tomita-Mitchell A. Altered contractility, Ca<sup>2+</sup> transients, and cell morphology seen in a patient-specific iPSC-CM model of Ebstein's anomaly with left ventricular noncompaction. Am J Physiol Heart Circ Physiol. 2023 Jul 01;325(1):H149-H162. PMCID: PMC10312315
 
Books, Chapters, and Reviews
1. Frommelt MA, Frommelt PC. Advances in echocardiographic modalities. Ped Clinics of North America 46 (2): 427-39, 1999.
2. Frommelt PC, Frommelt MA. Congenital coronary artery anomalies. Ped Clinics of North America 51:1273-88, 2004.
3. Frommelt MA, Frommelt PC. Cyanosis. In Practical Strategies in Pediatric Diagnosis and Therapy, Second Edition. Kliegman RM, Greenbaum LA, Lye PS, editors. 2004, Elsevier Saunders.
4. Tweddell J, Hoffman G, Ghanayem N, Frommelt M, Mussato K, PhD, and Berger S. Hypoplastic Left Heart Syndrome. In: Moss and Adams' Heart Disease in Infants, Children, and Adolescents Including Fetus and Young Adults, Seventh Edition; Vol 2; 2008 by Lippincott Williams and Wilkins.
5. Frommelt PC, Frommelt MA: Vascular Abnormalities: Arteriovenous Fistula, Pulmonary AV Fistula, Coronary Artery Abnormalities (anomalous Origin of Coronary Artery, Coronary Fistula, Congenital Aneurysms, Acquired Coronary Abnormalities - Kawasaki Disease). In: Echocardiography in Pediatric and Adult Congenital Heart Disease, edited by Eidem, Cetta and O'Leary. Philadelphia, Lippincott, Williams and Wilkins, 2009.
6. Frommelt MA. Cardiac Tumors. Echocardiography in Pediatric and Congenital Heart Disease from Fetus to Adult. P 547-55. Editors Lai W, Mertens L, Cohen M, Gena T. New Jersey. Wiley-Blackwell. 2009.
7. Tweddell J, Hoffman G, Ghanayem N, Frommelt M, Mussato K, PhD, and Berger S. Hypoplastic Left Heart Syndrome. In: Moss and Adams' Heart Disease in Infants, Children, and Adolescents Including Fetus and Young Adults, Eighth Edition; Vol 2; 2013 by Lippincott Williams and Wilkins.
8. Frommelt PC, Frommelt MA: Vascular Abnormalities: Arteriovenous Fistula, Pulmonary AV Fistula, Coronary Artery Abnormalities (anomalous Origin of Coronary Artery, Coronary Fistula, Congenital Aneurysms, Acquired Coronary Abnormalities - Kawasaki Disease). In: Echocardiography in Pediatric and Adult Congenital Heart Disease, edited by Eidem, Cetta and O'Leary. Philadelphia, Lippincott, Williams and Wilkins, Second Edition, 2014.
9. Frommelt, MA. Challenges and Controversies in Fetal Diagnosis and Treatment: Hypoplastic Left Heart Syndrome. Clinics in Perinatology on Controversies in Perinatology, edited by Drs. Robert M. Kliegman and Robert H. Lane.