CURRICULUM VITAE
Alison J. Kriegel PhD
Alison J. Kriegel PhD
Associate Professor
Department of Physiology
Department of Physiology
OFFICE ADDRESS: |
Basic Science Building |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
EDUCATION: |
09/1996 - 05/2001 B.S., University of Wisconsin-Milwaukee, Milwaukee, WI |
1996 - 2001 BS Biological Sciences, University of Wisconsin - Milwaukee, Milwaukee, WI |
08/2002 - 05/2004 Graduate studies in exercise physiology, no degree, Marquette University, Milwaukee |
2002 - 2003 Marqutte University, Milwaukee, WI |
08/2004 - 09/2008 Ph.D., Medical College of Wisconsin, Milwaukee, WI |
2004 - 2008 PhD, Medical College of Wisconsin, Milwaukee, WI |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
2008 - 2012 Postdoctoral Fellow, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 |
08/2009 - 06/2012 Postdoctoral Fellow, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 |
08/2013 - 05/2015 Clinical Research Scholar's Program, Clinical and Translational Sciences Institute, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226 |
2013 - Present Clinical Research Scholars Program, Medical College of Wisconsin, 8701 Watertwon Plank Road, Milwaukee, WI 53226 |
02/2020 - Present Women's Leadership Pilot Program, Center for the Advancement of Women in Science and Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 |
09/2021 - Present Research and Commmunity Scholars Program, Cancer Center, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226 |
FACULTY APPOINTMENTS: |
100 - Present N. East Ave., Waukesha, Wisconsin 53186 |
700 - Present West State Street, Milwaukee, WI 53233-1443 |
01/2007 - 07/2008 Adjunct Faculty, Department of Cardiovascular Medicine, Carroll University |
01/2009 - 05/2009 Instructor, Natural Sciences Department, Milwaukee Area Technical College |
07/2012 - 06/2017 Assistant Professor, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 |
2012 - Present Assistant Professor, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 |
03/2017 - Present Secondary Appointment, School of Pharmacy Medical College of Wisconsin |
07/2017 - Present Associate Professor, Department of Physiology, 8701 Watertown Plank Road, Medical College of Wisconsin, WI 53226 |
07/2020 - Present Nephrology Research Leader, Department of Pediatrics, Children's Research Institute, Medical College College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 |
07/2020 - Present Secondary Appointment, Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
08/01/2016 - Present Course Director, Translational Genetics/Genomics Course, Clinical and Translational Sciences Institute, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI 53226 |
04/01/2019 - Present Associate Director, Master's of Medical Physiology Program, Graduate School of Biomedical Sciences, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI 53226 |
06/01/2020 - Present Co-Director, Molecular and Cellular Research Scholarly Pathway, Medical School, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI 53226 |
AWARDS AND HONORS: |
2010 - 2011 Innovation Award, Biotechnology and Bioengineering Center - MCW |
2017 - 2018 Outstanding Graduate School Educator Recognition, Graduate School of Biomedical Sciences, MCW |
2018 - 2019 Outstanding Graduate School Educator Recognition, Graduate School of Biomedical Sciences, MCW |
2019 - 2020 Outstanding Graduate School Educator Recognition, Graduate School of Biomedical Sciences, MCW |
2020 - 2021 Outstanding Medical Student Teacher Recognition, Renal Physiology, Medical School - MCW |
2020 - 2021 Outstanding Graduate School Educator Recognition, Graduate School of Biomedical Sciences, MCW |
- 05/2018 Elected Fellow of the American Heart Association (FAHA) Council on Kidney in Cardiovascular Disease, American Heart Association |
- 2015 MCW Research Day Poster Award, Junior Faculty, Medical College of Wisconsin |
- 2011 Outstanding Woman Postdoctoral Researcher Award, Edward J. Lennon M.D. Award |
- 2013 MCW Research Day Poster Award, Junior Faculty: Basic Research, Medical College of Wisconsin |
- 2013 Outstanding Paper by a Junior Investigator, Physiological Genomics Group |
- 2020 Mentor of the Year, Graduate School of Biomedical Scientist , Medical College of Wisconsin |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
2010 - Present American Heart Association (member) |
2012 - Present American Physiological Society (member) |
2017 - Present American Society for Nephrology (member) |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
07/2021 - Present Associate Editor, Physiological Genomics |
Editorial Board |
07/01/2015 - Present Physiological Genomics |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
07/01/2019 - Present Member, Executive Board, Milwaukee Chapter, American Heart Association |
07/2021 - Present Co-Chair, Search Committee, Pediatric Nephrology Chief, MCW |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2014 - 2019 Trainee Advisory Chair, Physiological (Gen)Omics Steering Committee, APS |
04/2017 - Present Peer Reviewer, Cardiorenal Clinical Committee, Career Development, American Heart Association |
07/01/2017 - 06/30/2020 Joint Programming Committee Representative, Physiological (Gen)Omics Interest Group, American Physiological Society |
11/2018 - Present Peer Reviewer, Innovative Project Award – Clinical-Population Sciences, American Heart Association |
07/01/2019 - 06/30/2022 Secretary, Renal Section Steering Committee, American Physiological Society |
07/01/2019 - 06/30/2021 Member, Scientific & Clinical Education Lifelong Learning Committee
(SCILL) of the Council on The Kidney in Cardiovascular Diseas, American Heart Association |
04/2020 - 04/2023 Chair, Physiologic Omics Group, American Physiological Society |
- 10/2019 Ad Hoc Peer Reviewer, HIV Comorbidities and Clinical Studies, NIH |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Regional |
Alison Kriegel, Consequences of impaired autoregulation of renal blood flow, Invited Speaker, Vasculata, Milwaukee, WI, - 07/17/2018 |
National |
Alison Kriegel, Beyond Biomarkers: microRNAs as Mediators of Cardiac Pathology in CKD, Invited Lecture, University of Mississippi Medical Center, Jackson, MS, - 10/09/2016 |
Alison Kriegel, Session: Genetics and epigenetics in renal physiology and kidney disease; MicroRNA mediators of renal injury and chronic reno-cardiac syndrome, APS Conference and Control of Renal Function in Health and Disease, Charlottesville, VA, - 06/17/2019 |
Alison Kriegel, Cardiorenal syndrome in progress: molecular regulation of cardiac pathology with chronic insufficiency, Invited Speaker, Oregon Health Sciences University, Portland, OR, - 08/09/2019 |
Alison Kriegel, The heart-kidney connection in health and disease, Invited Speaker, Portland Veterans Affairs Medical Center, Portland, OR, - 08/09/2019 |
Alison Kriegel, Session: Cardio-renal Syndrome: Transitions to Chronicity; Cardiovascular Changes Associated with the Progression of Renal Tubular Pathology, AHA Scientific Sessions 2018, Chicago, IL, - 11/10/2018 |
Alison Kriegel, MicroRNA mediators of chronic renocardiac syndrome: Who are they and where do they come from?, Invited Lecture, University of Alabama-Birmingham, Birmingham, AL, - 02/16/2016 |
Alison Kriegel, Session: Cardiorenal Syndrome: Blame the Messanger; The Coding and Noncoding Genes Influencing Cardiorenal Syndrome, ASN Kidney Week 2018, San Diego, CA, - 10/26/2018 |
Alison Kriegel, Invited Lecture, Delaying End-Stage Renal Disease: Insights from Unbiased Multi-Omics Analysis, Medical College of Georgia, Augusta, GA, - 11/2021 |
Alison Kriegel, Characterization of microRNAs enriched in specific cell types and primary tissue types in solid organs, Physiological Genomoics Research Group 2014, San Diego Convention Center, San Diego, CA, - 10/26/2014 |
International |
Alison Kriegel, Invited Lecture, Europhysiology 2020, meeting cancelled due to COVID-19 pandemic, Berlin, Germany, - 2020 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
Local |
Kriegel AJ, Li P, Greene AS, Brown norway chromosome 16 substitution in salt-sensitive Bahl rats results in increased expression of cardioprotective genes in the left ventricle, MCW Research Day, Milwaukee WI, 2009 - Present |
Regional |
Kriegel AJ, Mladinov D, Kelly H, Langenstroer P, See W, Liang M, Interstitial fibrosis in the renal inner medulla in humans is associated with up-regulation of miR-382 and down-regulation of kallikrein 5, CTSI Milwaukee Regional Research Forum, Milwaukee WI, 2011 - Present |
National |
Kriegel AJ, Greene AS, SS-16BN/Mcwi model of HCM exhibits reduced left ventricular function with age, Experimental Biology, Washington DC, - 2007 |
Kriegel AJ, Liu Y, Cabacungan E, Liu P, Liang M, Deep sequencing of microRNAs in medullary thick ascending limbs isolated from firotic and non-fibrotic regions of the kidney in the dahl salt-sensitive rat., High Blood Pressure Research Scientific Sessions, Washington DC, - 2012 |
Olson J, Liu Y, Yan Y, Bai X, Kriegel AJ, Laing M, Boznjak Z, MicroRNA expression profiling of in vivo and in vitro cardiac models after isoflurane exposure, American Society of Anesthesiologists Meeting, San Francisco CA, - 2012 |
Kriegel AJ, Liu Y, Liu P, Cowley AW, Liang M, MicroRNA deep sequencing reveals altered expression in the left ventricle in a rat model of chronic renocardiac syndrome, AHA Scientific Sessions, Los Angeles CA, - 2012 |
Kriegel AJ, Cowley AW, Liang M, The upregulation of microRNA miR-21 mediates concentric left ventricle remodeling in a rat model of chronic renocardia syndrome, AHA Scientific Sessions, Dallas TX, - 2013 |
Kriegel AJ, Liu Y, Fang Y, Mladinov D, Ding X, Liang M, A novel role for miR-382: targeting of SOD2 during TGFb1-induced loss of epithelial characteristicsin human epithelial cells, American Society for Nephrology, Denver CO, - 2010 |
Kriegel AJ, Greene AS, Brown norway chromosome 16 protects the SS-16/Mcwi consomic model of left ventricular hypertophy from progressing to heart failure, Experimental Biology Meeting, San Diego CA, - 2008 |
Kriegel AJ, Liu P, Casati M, Cowley AW, Liang M, 5/6 Nephrechtomy Induces Changes in Immune and Inflammatory Gene Expression in the Left Ventricle, Experimental Biology Meeting, Boston, MA, - 03/29/2015 |
Chuppa S, Kriegel AJ, Low-dose Clofibrate Protects the Heart and Kidney in the 5/6 NX Model of Chronic Kidney Disease, AHA Scientific Sessions, Orlando, FL, - 11/08/2015 |
Kriegel AJ, Usa K, Liang M, MicroRNA miR-382 contributes to the development of renal interstitial fibrosis, American Society for Nephrology, Denver CO, - 2010 |
Paterson M, Chuppa S, Kriegel AJ, RNA-Sequencing Based Approach to Indentify Novel Pathways Regulating Atrophic and Hypertrophic Renal Remodeling, ASN Kidney Week, New Orleans, LA, - 11/04/2017 |
Kriegel AJ, Liu Y, Liu P, Baker MA, Hodges MR, Hua X, Liang M, Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs, American Physiological Society Physiological Genomics Research Group, - 2014 |
Kriegel AJ, Mladinov D, Kelly H, Langenstroer P, See W, Liang M, Interstitial fibrosis in the renal inner medulla in humans is associated with the up-regulation of miR-382 and down-regulation of kallikrein 5, Trainee Highlites in Physiological Genomics, Washington DC, - 2011 |
International |
Kriegel AJ, Greene AS, Reduced capillary to fiber ratio in consomic SS-16BN/Mcwi rats and diminished cardiac function, 8th World Congress for Microcirculation, Milwaukee WI, 2007 - Present |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
2010 - 2012 member, MCW Postdoctoral Advisory Committee, Medical College of Wisconsin |
2012 - 2014 Reviewer, Pilot Grant Review, Clinical and Translational Science Institute, Medical College of Wisconsin |
2012 - 2013 Judge, Graduate Student Poster Day - Research, Medical College of Wisconsin |
2014 - 2020 Member, Admissions Committee, Medical College of Wisconsin |
08/2016 - 07/2017 Member, Graduate Student Conference Education Award Committee, Graduate School of Biomedical Sciences, Medical College of Wisconsin |
07/2017 - Present Chair, Graduate Student Conference Education Award Committee, Graduate School of Biomedical Sciences, Medical College of Wisconsin |
08/2018 - 07/2021 Member, Institutional Animal Care and Use Committee, Medical College of Wisconsin |
07/2019 - 06/2021 Secondary Member, Physiology Representative, Graduate Faculty Council, Medical College of Wisconsin |
07/2019 - Present Representative, Interdisciplinary Course Directors Group, Physiology, Medical College of Wisconsin |
09/2019 - Present Member, Ambassador Workgroup, Graduate School of Biomedical Sciences, Medical College of Wisconsin |
10/2020 - Present Member, Ad Hoc Committee on Graduate School Holistic Admissions, Medical College of Wisconsin |
07/2021 - 06/2024 Representative, Graduate Faculty Council, Physiology, Medical College of Wisconsin |
MEDICAL COLLEGE TEACHING ACTIVITIES: |
Medical Student Education |
2006 - 2011 Teaching Assistant - Medical Physiology laboratory course work |
08/2016 - Present Course Director and Lecturer for Translational Genetics Course offered through the CTSI |
04/2019 - Present Instructor Symptoms Course (Dyspnea Lecture), M2 |
10/2019 - Present Lecturer for Renal Block, M2 |
06/2020 - Present Co-Director and Lecturer Molecular and Cellular Research Scholarly Pathway |
Resident and Fellow Education |
08/2017 - 12/2017 Course Director and Lecturer for Translational Genetics |
01/2020 - Present Course Co-Director and Lecturer for Translational Genetics |
Graduate Student Education |
2014 - 2019 Instructor for Physiological Genomics sction on microRNAs |
08/2016 - 12/2017 Course Directory and Lecturer for Translational Genomics |
03/2017 - Present Mock-grant reviewer for Physiological Genomics |
04/2019 - Present Associate Director, Master's of Medical Physiology Program |
08/2019 - Present Lecturer for Foundations fo Biological Sciences, Cardiovascular Physiology |
09/2019 - Present Instructor, Peer Review, Professional Development |
01/2020 - Present Course Director and Lecturer for Translational Genomics |
11/2021 - Present Instructor, Biological Sciences, Foundations of Biological Sciences III Course, Renal Physiology |
- 09/2021 Lecturer, Current Concepts in Cardiovascular Biology |
- 12/2018 Lecturer, Advanced Systems Physiology, Renal Section |
Pharmacy Student Education |
10/2017 - Present Instructor Human Anatomy and Physiology, Cardiovascular and Renal Content |
EXTRAMURAL TEACHING: |
Community/Lay Public |
2002 - 2003 Marquette University, Laboratory teaching assistant for undergraduate biology and physiology courses |
2007 - 2008 Caroll College, Waukesha, Wisconsin - Adjunct Professor, Instuctor for lecture and laboratory Intro to Physiology, Human Physiology, Anatomy and Physiology |
- 2009 Milwaukee Area Technical College, Instructor - Introduction to Anatomy and Physiology course |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Medical Students |
Medical College of Wisconsin, 2010 - 2014 Research Mentor |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Undergraduate Students |
Medical College of Wisoconsin, 2010 - 2014 Research Mentor |
COMMUNITY SERVICE ACTIVITIES: |
10/2012 - 03/2013 Science Fair Mentor to 6th and 7th graders at St. Matthais Parish School, Milwaukee, WI |
2012 - 2015 Medical College of Wisconsin's BBC Education Outreach Program. Served as a Junior High School and Elementary School Science Mentor. |
2012 - 2013 High School Science Fair Judge, Nicolet High School, Glendale, WI |
03/2014 - 04/2014 Club Invention Instructor (Grades K-3), Parkview Elementary School, Cedarburg, WI |
10/10/2014 Discussed careers in biomedical science with students as part of "Career Day", Grafton High School, Grafton, WI |
12/2014 - 04/2016 Science fair mentor to 4th and 5th graders at Wauwatosa STEM, Webster Elementary School, Wauwatosa, WI |
2014 - 2019 Project Lead the Way Advisory Board, Grafton High School, Grafton, WI |
08/2015 - 02/2016 Faculty mentor for DRIVE2 program (MCW) for high school students from Milwaukee Academy of Science & High School of Health Sciences |
11/2016 - 04/2017 Destination Imagination Team Manager, Parkview Elementary School, Cedarburg, WI |
03/10/2018 Introduction to Physiology Lecture, Student Enrichment Program for Underrepresented Professions (STEP-UP) Program (MCW) |
09/2018 - 09/2019 "STEAM Day" presenter introducing a career in biomedical sciences for 3-5th graders, Parkview Elementary School, Cedarburg, WI |
11/2018 - 05/2020 Volunteer for HOPE Network for Single Mothers, Newsletter researcher and scholarship committee |
12/07/2018 "PLTW Biomedical Conference" at Concordia University, presenter introducing a career in physiology and basic cardiovascular principles for freshman and sophomores |
08/2019 - Present UW-Milwaukee Fostering Success Committee, provides comprehensive support and assistance to college students who have left the foster care system |
12/2019 - 05/2020 Member, STEAM Fair Organizing Committee, Webster Middle School, Cedarburg, WI |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. de Resende MM, Kriegel AJ, Greene AS. Combined effects of low-dose spironolactone and captopril therapy in a rat model of genetic hypertrophic cardiomyopathy. J Cardiovasc Pharmacol. 2006 Dec;48(6):265-73. |
2. Kriegel AJ, Greene AS. Substitution of Brown Norway chromosome 16 preserves cardiac function with aging in a salt-sensitive Dahl consomic rat. Physiol Genomics. 2008 Dec 12;36(1):35-42. PMCID: PMC2604784 |
3. Kriegel AJ, Fang Y, Liu Y, Tian Z, Mladinov D, Matus IR, Ding X, Greene AS, Liang M. MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor beta 1: a novel role of miR-382. Nucleic Acids Res. 2010 Dec;38(22):8338-47. PMCID: PMC3001085 |
4. Kriegel AJ, Liu Y, Cohen B, Usa K, Liu Y, Liang M. MiR-382 targeting of kallikrein 5 contributes to renal inner medullary interstitial fibrosis. Physiol Genomics. 2012 Feb 27;44(4):259-67. PMCID: PMC3289118 |
5. Kriegel AJ, Liu Y, Fang Y, Ding X, Liang M. The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury. Physiol Genomics. 2012 Feb 27;44(4):237-44. PMCID: PMC3289120 |
6. Kriegel AJ, Mladinov D, Liang M. Translational study of microRNAs and its application in kidney disease and hypertension research. Clin Sci (Lond). 2012 May 01;122(10):439-47. PMCID: PMC4428581 |
7. Kriegel AJ, Didier DN, Li P, Lazar J, Greene AS. Mechanisms of cardioprotection resulting from Brown Norway chromosome 16 substitution in the salt-sensitive Dahl rat. Physiol Genomics. 2012 Aug 17;44(16):819-27. PMCID: PMC3774569 |
8. Xu X, Kriegel AJ, Liu Y, Usa K, Mladinov D, Liu H, Fang Y, Ding X, Liang M. Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21. Kidney Int. 2012 Dec;82(11):1167-75. PMCID: PMC3777822 |
9. Xu X, Kriegel AJ, Liu Y, Usa K, Mladinov D, Liu H, Fang Y, Ding X, Liang M. Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21. Kidney Int. 2012 Dec;82(11):1167-75. PMCID: PMC3777822 |
10. Fang Y, Yu X, Liu Y, Kriegel AJ, Heng Y, Xu X, Liang M, Ding X. miR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-α activation. Am J Physiol Renal Physiol. 2013 May 15;304(10):F1274-82. PMCID: PMC3651624 |
11. Yu X, Lu C, Liu H, Rao S, Cai J, Liu S, Kriegel AJ, Greene AS, Liang M, Ding X. Hypoxic preconditioning with cobalt of bone marrow mesenchymal stem cells improves cell migration and enhances therapy for treatment of ischemic acute kidney injury. PLoS One. 2013;8(5):e62703. PMCID: PMC3650042 |
12. Jia P, Teng J, Zou J, Fang Y, Jiang S, Yu X, Kriegel AJ, Liang M, Ding X. Intermittent exposure to xenon protects against gentamicin-induced nephrotoxicity. PLoS One. 2013;8(5):e64329. PMCID: PMC3667819 |
13. Kriegel AJ, Liu Y, Liu P, Baker MA, Hodges MR, Hua X, Liang M. Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs. Physiol Genomics. 2013 Dec 01;45(23):1144-56. PMCID: PMC3882707 |
14. Kriegel AJ, Liang M. MicroRNA in situ hybridization for formalin fixed kidney tissues. J Vis Exp. 2013 Nov 30(81). PMCID: PMC3992125 |
15. Xu X, Kriegel AJ, Jiao X, Liu H, Bai X, Olson J, Liang M, Ding X. miR-21 in ischemia/reperfusion injury: a double-edged sword? Physiol Genomics. 2014 Nov 01;46(21):789-97. PMCID: PMC4280148 |
16. Olson JM, Yan Y, Bai X, Ge ZD, Liang M, Kriegel AJ, Twaroski DM, Bosnjak ZJ. Up-regulation of microRNA-21 mediates isoflurane-induced protection of cardiomyocytes. Anesthesiology. 2015 Apr;122(4):795-805. PMCID: PMC4366274 |
17. Kriegel AJ, Baker MA, Liu Y, Liu P, Cowley AW Jr, Liang M. Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes. Hypertension. 2015 Oct;66(4):793-9. PMCID: PMC4567475 |
18. Kriegel AJ, Gartz M, Afzal MZ, de Lange WJ, Ralphe JC, Strande JL. Molecular Approaches in HFpEF: MicroRNAs and iPSC-Derived Cardiomyocytes. J Cardiovasc Transl Res. 2017 Jun;10(3):295-304. PMCID: PMC5937699 |
19. Usa KS, Liu Y, Kurth T, Kriegel AJ, Mattson DL, Cowley AW Jr, Liang M. Renal Delivery of Anti-microRNA Oligonucleotides in Rats. Methods Mol Biol. 2017;1527:409-419. |
20. Paterson MR, Kriegel AJ. MiR-146a/b: a family with shared seeds and different roots. Physiol Genomics. 2017 Apr 01;49(4):243-252. PMCID: PMC5407182 |
21. Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, Patullo L, Kriegel AJ. MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4. Kidney Int. 2018 Feb;93(2):375-389. PMCID: PMC5787401 |
22. Widlansky ME, Jensen DM, Wang J, Liu Y, Geurts AM, Kriegel AJ, Liu P, Ying R, Zhang G, Casati M, Chu C, Malik M, Branum A, Tanner MJ, Tyagi S, Usa K, Liang M. miR-29 contributes to normal endothelial function and can restore it in cardiometabolic disorders. EMBO Mol Med. 2018 Mar;10(3). PMCID: PMC5840545 |
23. Miller JJ, Aoki K, Mascari CA, Beltrame AK, Sokumbi O, North PE, Tiemeyer M, Kriegel AJ, Dahms NM. α-Galactosidase A-deficient rats accumulate glycosphingolipids and develop cardiorenal phenotypes of Fabry disease. FASEB J. 2019 Jan;33(1):418-429. PMCID: PMC6629127 |
24. Kriegel AJ, Terhune SS, Greene AS, Noon KR, Pereckas MS, Liang M. Isomer-specific effect of microRNA miR-29b on nuclear morphology. J Biol Chem. 2018 Sep 07;293(36):14080-14088. PMCID: PMC6130969 |
25. Baker MA, Wang F, Liu Y, Kriegel AJ, Geurts AM, Usa K, Xue H, Wang D, Kong Y, Liang M. MiR-192-5p in the Kidney Protects Against the Development of Hypertension. Hypertension. 2019 Feb;73(2):399-406. PMCID: PMC6339564 |
26. Nasci VL, Chuppa S, Griswold L, Goodreau KA, Dash RK, Kriegel AJ. miR-21-5p regulates mitochondrial respiration and lipid content in H9C2 cells. Am J Physiol Heart Circ Physiol. 2019 Mar 01;316(3):H710-H721. PMCID: PMC6459316 |
27. Ilatovskaya DV, Levchenko V, Pavlov TS, Isaeva E, Klemens CA, Johnson J, Liu P, Kriegel AJ, Staruschenko A. Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC). EBioMedicine. 2019 Feb;40:663-674. PMCID: PMC6413684 |
28. Liu Y, Kriegel AJ, Liang M. Library Preparation for Multiplexed Reduced Representation Bisulfite Sequencing with a Universal Adapter. Methods Mol Biol. 2019;2018:177-194. |
29. Lai PY, Jing X, Michalkiewicz T, Entringer B, Ke X, Majnik A, Kriegel AJ, Liu P, Lane RH, Konduri GG. Adverse early-life environment impairs postnatal lung development in mice. Physiol Genomics. 2019 Sep 01;51(9):462-470. PMCID: PMC6766700 |
30. Hader SN, Zinkevich N, Norwood Toro LE, Kriegel AJ, Kong A, Freed JK, Gutterman DD, Beyer AM. Detrimental effects of chemotherapy on human coronary microvascular function. Am J Physiol Heart Circ Physiol. 2019 Oct 01;317(4):H705-H710. PMCID: PMC6843017 |
31. Abais-Battad JM, Alsheikh AJ, Pan X, Fehrenbach DJ, Dasinger JH, Lund H, Roberts ML, Kriegel AJ, Cowley AW Jr, Kidambi S, Kotchen TA, Liu P, Liang M, Mattson DL. Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome. Hypertension. 2019 Oct;74(4):854-863. PMCID: PMC6739138 |
32. Paterson MR, Geurts AM, Kriegel AJ. miR-146b-5p has a sex-specific role in renal and cardiac pathology in a rat model of chronic kidney disease. Kidney Int. 2019 Dec;96(6):1332-1345. PMCID: PMC6941490 |
33. MacKay, M.J., Hooker, A.C., Afshinnekoo, E., Salit, M., Kelly, J., Feldstein, J.V., Haft, N., Schenkel, D., Nambi, S., Cai, Y., Zhang, F., Church, G., Dia, J., Wang, C.L., Levy, S., Huber, J., Ji, H.P., Kriegel, AJ, Wyllie, A.L., & Mason, C.E. The COVID-19 XPRIZE and the need for scalable, fast and widespread testing. Nature biotechnology, 38(9), 1021-1024. PMID: 32820257 |
34. Adam RJ, Paterson MR, Wardecke L, Hoffman BR, Kriegel AJ. Functionally Essential Tubular Proteins are Lost to Urin-Excreted, Large Extracellular Vesicles During Chronic Renal Insuffiiency. Kidney360. 2020 Oct;1(10):1105-1115. Epub 2020 Ooct 29. PMID: 34263177 |
35. Klemens CA, Chulkov EG, Wu J, Hye Khan MA, Levchenko V, Flister MJ, Imig JD, Kriegel AJ, Palygin O, Staruschenko A. Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores. Hypertension. 2021 Feb;77(2):582-593. PMID: 33390052 |
36. Spires DR, Palygin O, Levchenko V, Isaeva E, Klemens CA, Khedr S, Nikolaienko O, Kriegel A, Cheng X, Yeo JY, Joe B, Staruschenko A. Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats. Physiol Genomics. Jun 1;53(6):223-234. PMCID: PMC8285576 |
37. Gohar EY, De Miguel C, Obi IE, Daugherty EM, Hyndman KA, Becker BK, Jin C, Sedaka R, Johnston JG, Liu P, Speed JS, Mitchell T, Kriegel AJ, Pollock JS, and Pollock DM. Acclimation to a High Salt Diet is Sex Dependent. JAHA Accepted 08/03/2021 DOI: 10.1161/JAHA.120.020450 |
38. Adam RJ, Paterson MR, Wardecke L, Hoffmann BR, Kriegel AJ. Functionally Essential Tubular Proteins Are Lost to Urine-Excreted, Large Extracellular Vesicles during Chronic Renal Insufficiency. Kidney360. 2020 Oct;1(10):1105-1115. PMCID: PMC8276873 |
39. Klemens CA, Chulkov EG, Wu J, Hye Khan MA, Levchenko V, Flister MJ, Imig JD, Kriegel AJ, Palygin O, Staruschenko A. Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores. Hypertension. 2021 Feb;77(2):582-593. PMCID: PMC7856014 |
40. Spires DR, Palygin O, Levchenko V, Isaeva E, Klemens CA, Khedr S, Nikolaienko O, Kriegel A, Cheng X, Yeo JY, Joe B, Staruschenko A. Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats. Physiol Genomics. 2021 Jun 01;53(6):223-234. PMCID: PMC8285576 |
41. MacKay MJ, Hooker AC, Afshinnekoo E, Salit M, Kelly J, Feldstein JV, Haft N, Schenkel D, Nambi S, Cai Y, Zhang F, Church G, Dai J, Wang CL, Levy S, Huber J, Ji HP, Kriegel A, Wyllie AL, Mason CE. The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing. Nat Biotechnol. 2020 Sep;38(9):1021-1024. PMCID: PMC7543743 |
42. Moore KJM, Cahill J, Aidelberg G, Aronoff R, Bektaş A, Bezdan D, Butler DJ, Chittur SV, Codyre M, Federici F, Tanner NA, Tighe SW, True R, Ware SB, Wyllie AL, Afshin EE, Bendesky A, Chang CB, Dela Rosa R 2nd, Elhaik E, Erickson D, Goldsborough AS, Grills G, Hadasch K, Hayden A, Her SY, Karl JA, Kim CH, Kriegel AJ, Kunstman T, Landau Z, Land K, Langhorst BW, Lindner AB, Mayer BE, McLaughlin LA, McLaughlin MT, Molloy J, Mozsary C, Nadler JL, D'Silva M, Ng D, O'Connor DH, Ongerth JE, Osuolale O, Pinharanda A, Plenker D, Ranjan R, Rosbash M, Rotem A, Segarra J, Schürer S, Sherrill-Mix S, Solo-Gabriele H, To S, Vogt MC, Yu AD, Mason CE, gLAMP Consortium. Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications. J Biomol Tech. 2021 Sep;32(3):228-275. PMCID: PMC8802757 |
43. Jensen DM, Han P, Mangala LS, Lopez-Berestein G, Sood AK, Liu J, Kriegel AJ, Usa K, Widlansky ME, Liang M. Broad-acting therapeutic effects of miR-29b-chitosan on hypertension and diabetic complications. Mol Ther. 2022 Nov 02;30(11):3462-3476. PMCID: PMC9637778 |
44. Mukherjee D, Rana U, Kriegel AJ, Liu P, Michalkiewicz T, Konduri GG. Fetal pulmonary hypertension: dysregulated microRNA-34c-Notch1 axis contributes to impaired angiogenesis in an ovine model. Pediatr Res. 2023 Feb;93(3):551-558. PMCID: PMC9759620 |
45. Ilatovskaya DV, Levchenko V, Winsor K, Blass GR, Spires DR, Sarsenova E, Polina I, Zietara A, Paterson M, Kriegel AJ, Staruschenko A. Effects of elevation of ANP and its deficiency on cardiorenal function. JCI Insight. 2022 May 09;7(9). PMCID: PMC9090260 |
46. Adam RJ, Williams AC, Kriegel AJ. Comparison of the surgical resection and infarct 5/6 nephrectomy rat models of chronic kidney disease. Am J Physiol Renal Physiol. 2022 Jun 01;322(6):F639-F654. PMCID: PMC9076416 |
47. Patil CN, Ritter ML, Wackman KK, Oliveira V, Balapattabi K, Grobe CC, Brozoski DT, Reho JJ, Nakagawa P, Mouradian GC Jr, Kriegel AJ, Kwitek AE, Hodges MR, Segar JL, Sigmund CD, Grobe JL. Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet. Am J Physiol Regul Integr Comp Physiol. 2022 Jun 01;322(6):R467-R485. PMCID: PMC9054347 |
48. Park J, Foox J, Hether T, Danko DC, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J, Shaiber A, Afshin EE, MacKay M, Rendeiro AF, Bram Y, Chandar V, Geiger H, Craney A, Velu P, Melnick AM, Hajirasouliha I, Beheshti A, Taylor D, Saravia-Butler A, Singh U, Wurtele ES, Schisler J, Fennessey S, Corvelo A, Zody MC, Germer S, Salvatore S, Levy S, Wu S, Tatonetti NP, Shapira S, Salvatore M, Westblade LF, Cushing M, Rennert H, Kriegel AJ, Elemento O, Imielinski M, Rice CM, Borczuk AC, Meydan C, Schwartz RE, Mason CE. System-wide transcriptome damage and tissue identity loss in COVID-19 patients. Cell Rep Med. 2022 Feb 15;3(2):100522. PMCID: PMC8784611 |
49. Gohar EY, De Miguel C, Obi IE, Daugherty EM, Hyndman KA, Becker BK, Jin C, Sedaka R, Johnston JG, Liu P, Speed JS, Mitchell T, Kriegel AJ, Pollock JS, Pollock DM. Acclimation to a High-Salt Diet Is Sex Dependent. J Am Heart Assoc. 2022 Mar;11(5):e020450. PMCID: PMC9075092 |
Editorials, Letters to Editor, Other |
1. Kriegel AJ. Connecting the Bench and Bedside. AHA/ASA Connections, quarterly newsletter, Fall 2017, pg.39. |