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CURRICULUM VITAE

Daniel J. Stein MD
Assistant Professor
Department of Medicine
Division of Gastroenterology

OFFICE ADDRESS:
Froedtert Hospital
9200 W Wisconsin Ave
Milwaukee, WI 53226

CITIZENSHIP:  United States

EDUCATION:
08/1989 - 05/1994 Diploma, Cudahy High School, Cudahy, WI
08/1994 - 05/1998 B.S. - Biology, Marquette University, Milwaukee, WI
08/1999 - 05/2003 M.D., Creighton University School of Medicine, Omaha, NE

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
07/01/2003 - 06/30/2006 Internal Medicine Internship and Residency, Internal Medicine, University of Arizona, Tucson, AZ
07/01/2007 - 06/30/2010 Gastroenterology and Hepatology Fellowship, Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI
11/01/2009 - 12/01/2009 Visiting Inflammatory Bowel Disease Fellow, Gastroenterology, University of Chicago, Chicago, IL

FACULTY APPOINTMENTS:
07/01/2010 - Present Assistant Professor, Internal Medicine, Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI
07/01/2010 - Present Gastroenterology and Hepatology, Children's Hospital of Wisconsin, Milwaukee, WI
07/01/2011 - Present Gastroenterology and Hepatology, Clement J. Zablocki Veterans Affairs Hospital, Milwaukee, WI

ADMINISTRATIVE APPOINTMENTS:
07/01/2006 - 06/30/2007 Chief Resident - Internal Medicine, Internal Medicine, University of Arizona Internal Medicine, Tucson, AZ
08/2013 - Present Access Champion for the Division of Gastroenterology and Hepatology, Internal Medicine, Gastroenterology and Hepatology, Froedtert and the Medical College of Wisconsin, Milwaukee, WI
06/01/2015 - Present Medical Director of the Inflammatory Bowel Disease Program at Froedtert and the Medical College of Wisconsin, Internal Medicine, Gastroenterology, Medical College of Wisconsin, Milwaukee, WI

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
06/01/2012 - Present Co-Director, M2 GI and Nutrition Subunit, Discovery Curriculum, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
06/03/2010 - Present Children's Hospital of WI, Milwaukee, WI
07/01/2010 - Present Froedtert Hospital, Milwaukee, WI
09/07/2010 - Present Froedtert Surgery Center, Milwaukee, WI
07/01/2011 - Present Zablocki VA Medical Center, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
Internal Medicine
08/2006
12/2016
Gastroenterology
10/2010
12/2020
 
Certificates
Issued By Issue DateExpiration
BLS
American Heart Association
03/2014
03/2016
ACLS
American Heart Association
07/2014
07/2016
 
Licensure
Number Issue DateExpiration
AZ Medicine and Surgery
35649
06/14/2006
02/05/2008
WI Medicine and Surgery
50499
06/12/2007
None
 
AWARDS AND HONORS:
1998 - Present Phi Beta Kappa , Marquette University
1998 - Present Magna Cum Laude , Marquette University
05/2000 - 08/2000 Crohn’s and Colitis Foundation of America: 2000 Solvay Pharmaceuticals Student Research Fellowship “Selective Leukocyte Binding by Microvascular Endothelial Cells in Crohn’s Disease” , Medical College of Wisconsin
10/2005 - Present Selected Attendee to 3rd Annual Choosing a Career in Academic Gastroenterology Conference, Medical College of Wisconsin – Division of Gastroenterology and Hepatology
2005 - 2007 Associate Representative, American College of Physicians
2006 - 2007 Chief Resident Internal Medicine , University of Arizona Internal Medicine Residency Program
2008 - Present Attendee , IBD Mentoring Program for GI Fellows
2010 - Present Fellowship2Leadership, Salix Fellows Program, DDW
07/01/2013 - 06/30/2014 MCW Outstanding Medical Student Teacher Pin, Medical College of Wisconsin

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
07/01/2007 - Present American College of Gastroenterology (Member)
07/01/2007 - Present Crohn's and Colitis Foundation of America (Member)
07/01/2007 - 07/01/2012 American Society for Gastrointestinal Endoscopists (Member)
07/01/2007 - Present American Gastroenterology Association
08/01/2011 - Present Milwaukee GI Society (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
2015 - Present Inflammatory Bowel Disease

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
06/01/2010 - Present Crohn's and Colitis Medical Advisory Board Milwaukee, Crohn's and Colitis Foundation of America, Milwaukee Chapter
03/2012 - Present Director, Annual Inflammatory Bowel Disease Update, Medical College of Wisconsin Inflammatory Bowel Disease Annual Update
01/01/2016 - Present Director, Crohn's and Colitis MCW and CHW Patient and Family Education Program, Medical College of Wisconsin
01/13/2016 - Present Board Member, Crohn's and Colitis Foundation of America Advisory Board, Crohn's and Colitis Foundation of America
01/17/2016 - Present Secretary/Treasurer, Milwaukee GI Society

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Non-Peer Review
Title:
A Long-Term Non-Interventional Registry to Assess Safety and Effectiveness of HUMIRA® (Adalimumab) in Patients with Moderately to Severely Active Ulcerative Colitis (UC)
Source:
Legacy
Role:
PI
 
Title:
A Phase 3, Open-label Study to Determine the Long-term Safety and Efficacy of Vedolizumab (MLN0002) in Patients with Ulcerative Colitis and Crohn’s Disease
Source:
Millennium
Role:
PI
 
Title:
A Non-Interventional Long-term Post-Marketing Registry of Patients Treated with Certolizumab Pegol (Cimzia®) for Crohn's Disease
Source:
SECURE
Role:
PI
 
Title:
AN OPEN-LABEL EXTENSION AND SAFETY MONITORING STUDY OF MODERATE TO SEVERE ULCERATIVE COLITIS PATIENTS PREVIOUSLY ENROLLED IN ETROLIZUMAB PHASE III STUDIES
Source:
GA29102
Role:
PI
 
Title:
PHASE III, DOUBLE BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE EFFICACY AND SAFETY OF ETROLIZUMAB DURING INDUCTION AND MAINTENANCE IN PATIENTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS WHO ARE REFRACTORY TO OR INTOLERANT OF TNF INHIBITORS
Source:
GA 28950
Role:
PI
 
Title:
A Multicenter, Open-Label Study to Evaluate the Long Term Efficacy, Safety, and Tolerability of Repeated Administration of Adalimumab in Subjects with Crohn's Disease
Source:
M14-347
Role:
PI
 
Title:
AN OPEN-LABEL EXTENSION AND SAFETY MONITORING STUDY OF MODERATE TO SEVERE ULCERATIVE COLITIS PATIENTS PREVIOUSLY ENROLLED IN ETROLIZUMAB PHASE III STUDIES
Source:
GA28951
Role:
PI
 
Title:
A Long-Term Non-Interventional Registry to Assess Safety and Effectiveness of HUMIRA® (Adalimumab) in Subjects with Moderately to Severely Active Crohn's Disease (CD)
Source:
Abbott
Role:
PI
 
Title:
A Double-Blind, Randomized, Multicenter Study of Higher Versus Standard Adalimumab Dosing Regimens for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
Source:
M14-033
Role:
PI
 
Title:
A Phase III Randomized, Double Blind, Placebo-controlled, Multicenter, Parallel Group Study to Assess the Efficacy and Safety of Fixed-dose Combination RHB-104 in Subjects with Moderately to Severely Active Crohn’s Disease
Role:
PI
 
Title:
A Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Two Adalimumab Induction Regimens in Subjects with Moderately to Severely Active Crohn's Disease and Evidence of Mucosal Ulceration
Source:
M14-115
Role:
PI
 
INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
1. Probiotics and Inflammatory Bowel Disease, Crohn’s and Colitis Foundation of America – Milwaukee Chapter Monthly Meeting, Milwaukee, WI, 05/10/2010
2. New Therapies in IBD, Crohn’s and Colitis Foundation of America – Milwaukee Chapter Monthly Meeting, Milwaukee, WI, 06/07/2010
3. Inflammatory Bowel Disease and The Endoscopy Lab, Froedtert Lutheran Memorial Hospital Gastroenterology Nursing Education Program, Milwaukee, WI, 08/03/2010
4. Update on the IBD Center, Digestive Disease Center Board Meeting, Milwaukee, WI, 10/2010
5. Lunch and Learn “The Celiac Iceberg”, Plank Road Clinic, Milwaukee, WI, 03/03/2011
6. Lunch and Learn “The Celiac Iceberg”, Sunnyslope Clinic, Milwaukee, WI, 03/16/2011
7. Lunch and Learn “The Celiac Iceberg”, Lincoln Avenue Clinic, Milwaukee, WI, 04/13/2011
8. Autonomic Dysfunction and the Gut, Milwaukee Autonomic Support Group, Milwaukee, WI, 02/2013 - Present
9. Optimizing Therapy for Crohn's Disease, Pharmacy Department Meeting, Froedtert Hospital, 02/10/2014
10. IBD and the Endoscopy Lab, Building a Better Team - Share Your Knowledge, Froedtert Hospital, 02/12/2014
11. Modern Disease Management in IBD, Allergy and Immunology Grand Rounds, Children's Hospital of Wisconsin, 03/07/2014
12. Update on the Inflammatory Bowel Disease Program, Digestive Disease Board Meeting 6/1/2015, Milwaukee, WI, 06/01/2015
13. Approach to Upper GI Bleeding in the CVICU, CVICU Lecture Series, Milwaukee, WI, 06/09/2015 - Present
 
Regional
1. Optimizing Therapy in Crohn's Disease, Medical College of Wisconsin Inflammatory Bowel Disease Update, Medical College of Wisconsin, 03/31/2012
2. Optimizing Therapy for Inflammatory Bowel Disease, Grand Rounds St. Agnes Hospital, Fond Du Lac, Wisconsin, 05/31/2012
3. Celiac Disease and Gluten Sensitivity, Medical College of Wisconsin Internal Medicine Grand Rounds, Milwaukee, WI, 04/05/2013
4. Therapeutic Drug Monitoring In Inflammatory Bowel Disease Patients, Medical College of Wisconsin IBD Update, Milwaukee WI, 04/13/2013
5. Disease and Drug Monitoring in Inflammatory Bowel Disease, MCW IBD Annual Update, Crowne Plaza Hotel - Wauwatosa, WI, 03/15/2014
6. Approach to Chronic Diarrhea, State of the Gut, Brookfield, WI, 09/19/2014
7. Modern Approach to Managing Inflammatory Bowel Disease, WSGNA 2014 Fall Conference, Brookfield, WI, 11/07/2014
8. Update on Crohn’s Disease Therapy, MCW IBD Annual Update, Milwaukee, WI, 03/14/2015
9. Modern Disease Management In Inflammatory Bowel Disease, CCFA Wisconsin Patient Education Program, Milwaukee, WI, 04/27/2015
10. Approach to Patient Care and Research at the Inflammatory Bowel Disease Program at the Medical College of Wisconsin, Digestive Disease Committee Pro-Am Golf Tournament Fundraiser, Milwaukee, WI, 08/24/2015
11. Digestive Disease Week Review - Inflammatory Bowel Disease, Digestive Disease Week Review, Milwaukee, WI, 09/17/2015
12. Clostridium Difficile Update, "State of the Gut" An Update on Gastrointestinal Disorders, Sheraton Brookfield Hotel, 09/18/2015
13. Inflammatory Bowel Disease Patient Question and Answers, Crohn's and Colitis Foundation of America Wisconsin Chapter Meeting, Milwaukee, WI, 10/03/2015
14. Inflammatory Bowel Disease: Taking Control of Your Disease, Froedtert Community Health Education Series, Milwaukee, WI, 11/03/2015
 
PEER REVIEWED WORKSHOPS/PRESENTATIONS:
National
1. Stein,D et. al., Inflammatory Bowel Disease Patients on Immunosuppressive Therapy in Endoscopic Remission Have a High Rate of Post Inflammatory Bowel Disease-Irritable Bowel Syndrome which is Associated with a Diminished Quality of Life., Digestive Disease Week 2012, San Diego, CA, 05/19/2012 - 05/22/2012
2. Modiri, A, Stein, D, et al, Inflammatory Bowel Disease Patients With Solid Organ Transplants Who Require Anti-TNF Therapy Are Not at Increased Risk of Serious Infections., Digestive Disease Week 2015, Washington D.C., 05/16/2015 - 05/19/2015
 
COMMITTEE SERVICE:
Medical College
2011 - Present Interviewer, Incoming Gastroenterology Fellowship Program Applicants, Medical College of Wisconsin
2011 - Present Interviewer, Internal Medicine Residency Program Applicants, Medical College of Wisconsin
06/01/2012 - Present Member, Directors of Medical Student Education Committee
06/01/2012 - Present Co-Director M2 GI and Nutrition Subunit, Discovery Curriculum, Medical College of Wisconsin
06/01/2012 - Present Member, M2 Unit Directors Committee, Medical College of Wisconsin
12/01/2013 - Present Member, Department of Medicine Access Champion Committee
06/01/2014 - Present Member, Division of Gastroenterology and Hepatology Recruitment Committee
06/01/2014 - Present Member, M2 year Curriculum Planning Committee for Medical College of Wisconsin - Green Bay
01/01/2015 - 06/30/2015 Fellow Improvement Sub-committee, Gastroenterology
05/01/2015 - Present Member, GI Daily Improvement Committee, Gastroenterology, Medicine
06/01/2015 - 07/30/2015 Member, Bonus Distribution Guideline Development Task Force, Medicine, Medical College of Wisconsin
 
Hospital
11/01/2014 - Present Member, Ambulatory Care Pharmacy and Therapeutics Committee
08/01/2015 - Present Member, Specialty Pharmacy/340B Advisory Group, GI, Pharmacy, Froedtert Hospital and Medical College of Wisconsin
01/20/2016 - Present Committee Member, MCP Patient Services and Operations Committee, Medical College Physicians
 
MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
06/01/2010 - Present M3 Board Review: GI and Hepatology Review
06/01/2010 - 06/01/2012 M4 Inflammatory Bowel Disease Rotation Attending
07/01/2010 - Present GI Consult Rotation: Outpatient Clinic Attending
06/01/2011 - Present Ambulatory Clinics Rotation Attending
01/01/2013 - Present M1 Clinical Apprenticeship Preceptor
01/09/2014 M2 GI&N Subunit Lecture: Pathology of the Esophagus and Stomach - Case Presentation
01/16/2014 M2 GI&N Subunit Lecture: Case of Weight Loss and Diarrhea
01/21/2014 M2 GI&N Subunit Lecture C. Difficle Colitis
01/21/2014 M2 GI&N Subunit Lecture Approach to Diarrhea
01/21/2014 M2 GI&N Subunit Lecture Miscellaneous Disorders of the GI Tract
01/22/2014 M2 GI&N Subunit Lecture: Celiac Disease
01/23/2014 M2 GI&N Subunit Lecture: Introduction to Inflammatory Bowel Disease
01/23/2014 M2 GI&N Lecture: Subunit Tumors of the Large and Small Bowel - Case based discussion
03/03/2014 ACP/student networking reception. Reception aimed at increasing student interest in Internal Medicine and Medicine Sub-Specialties
04/09/2014 Symptoms M2 Subunit. Lecture: Two Cases of Nausea, Vomiting and Weight Loss
04/09/2014 Symptoms M2 Subunit. Lecture: USMLE Board Review
01/08/2015 M2 GI&N Subunit Lecture: Pathology of the Esophagus and Stomach - Case Presentation
01/15/2015 M2 GI&N Subunit Lecture: Case of Weight Loss and Diarrhea
01/20/2015 M2 GI&N Subunit Lecture: Approach to Diarrhea
01/21/2015 Lecture: Case Based Review of the M2 GI&N Subunit
01/22/2015 M2 GI&N Subunit Lecture: Miscellaneous Disorders of the GI Tract
01/22/2015 M2 GI&N Subunit Lecture: Tumors of the Large and Small Bowel - Case Based Discussion
01/22/2015 M2 GI&N Subunit Lecture: Celiac Disease
01/22/2015 M2 GI&N Subunit Lecture: Introduction to Inflammatory Bowel Disease
03/26/2015 ACP/student networking reception. Reception aimed at increasing student interest in Internal Medicine and Medicine Sub-Specialties.
04/18/2015 Symptoms M2 Subunit. Lecture: Diarrhea
01/07/2016 Clinical Correlations: Upper GI Pathology
01/14/2016 GI&N M2 Subunit:Clinic Correlation: Pancreatic Case Discussion
01/20/2016 GI&N M2 Subunit: Approach to Diarrhea
01/20/2016 GI&N M2 Subunit: Gluten Sensitivity Disorders
01/20/2016 GI&N M2 Subunit: Introduction to Inflammatory Bowel Disease
01/21/2016 GI&N M2 Subunit: Clinical Correlations: Lower GI Pathology
01/26/2016 GI&N M2 Subunit: Breakfast Club Case Discussion
 
Resident and Fellow Education
06/01/2010 - Present IBD and Clinics Rotation Attending
06/01/2010 - Present GI Fellow Board Review: IBD and Infections of the GI Tract
07/01/2010 - Present Inflammatory Bowel Disease Inpatient Service Attending: Educate and supervise GI fellow and internal medicine residents on inpatient IBD service on a weekly basis
07/01/2010 - Present Attending GI Inpatient Consult Service: Teach Fellows, Residents and Students on Inpatient Consult Service
07/01/2010 - Present Teach and Supervise GI Fellows Learning Endoscopy at the Milwaukee VA Hospital
07/01/2010 - Present Clinical Seminar: GI Fellowship Recurring Meeting
07/01/2010 - Present Quality Assurance Meeting: GI Division Recurring Meeting
07/01/2010 - Present Journal Club: GI Fellows (Recurring Meeting)
07/01/2010 - Present Core Curriculum Conference: GI Fellows
07/01/2010 - Present GI Consult Rotation: Outpatient Clinic Attending
07/01/2012 - Present Attending: GI Fellow Continuity Clinic
07/01/2012 - Present Internal Medicine Noon Report Faculty
12/2012 - Present Lecture: Management of Inflammatory Bowel Disease for the Internist
04/2013 - Present Introduction to Endoscopy for First Year Surgical Resident
12/16/2013 - Present Lecture: Introduction to Inflammatory Bowel Disease
12/01/2014 - Present Lecture: Introduction to Inflammatory Bowel Disease
12/10/2015 Resident Academic Halfday lecture: Advanced IBD
 
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Undergraduate Students
Ann Nohl, Medical College of Wisconsin, 06/01/2011 - 07/01/2012 Research Mentor
 
Medical Students
Medical College of Wisconsin, 07/01/2012 - 05/01/2013 M4 Student Advisor
Imaan Ansari, Medical College of Wisconsin, 09/01/2013 - 06/30/2014 Research Mentor
David Ingram, Medical College of Wisconsin, 01/01/2014 - Present Quips Advisor/Scholarly Pathway
 
Clinical/Research Fellows
James Kwiatt, Medical College of Wisconsin, 07/01/2009 - 06/30/2011 Research Mentor
Syed Rizvi, Medical College of Wisconsin, 06/01/2012 - 06/01/2014 Research Mentor
Mukund Venu, Medical College of Wisconsin, 07/01/2012 - 06/30/2013 Research Mentor
Amar Naik, Medical College of Wisconsin, 07/01/2012 - 12/30/2014 Research Mentor
Alexandra Modiri, Medical College of Wisconsin, 06/01/2014 - Present Research Mentor
 
Residents
Sonja Bhati, Medical College of Wisconsin, 07/01/2010 - 06/30/2012 Research Mentor
Parin N. Desai, Medical College of Wisconsin, 06/01/2011 - 07/30/2012 Research Mentor
Amil Patel, Medical College of Wisconsin, 07/01/2011 - 06/30/2012 Research Mentor
Adeeti Chiplunker, Medical College of Wisconsin, 07/01/2012 - 06/30/2014 Research Mentor
Jennifer Cahill, Medical College of Wisconsin, 09/01/2014 - Present Research Mentor
 
Faculty
Vikram Kanagala, Medical College of Wisconsin, 07/01/2012 - 06/30/2015 Research Mentor
 
PROGRAMMATIC DEVELOPMENTS:
Educational Programs
Fellow
07/01/2010 - Present GI Fellow IBD/Clinics rotation: Instrumental in the design and development of the GI fellows IBD rotation
07/01/2010 - Present Visiting IBD Fellow Program: Coordinate and educate visiting GI fellows interested in learning more about the management IBD by rotating through our inflammatory bowel disease program.
09/01/2014 - Present Inflammatory Bowel Disease Working Group: Director of a monthly multidisciplinary meeting focusing on the management of IBD patients
 
 
Clinical Programs
06/01/2012 - Present Fecal Microbiota Transplant Program: Developed and organized the first regulated fecal microbiota transplant program in Southeastern Wisconsin for the treatment of Clostridium difficile infections.
01/01/2013 - Present IBD New Patient Intake Program: Developed an efficient and organized program aimed at optimizing the new patient experience for the Inflammatory Bowel Disease Program
01/2013 - Present Pharmacist Integration with IBD Program: Integrated pharmacist into IBD program helping to monitor and to teach patients about their immunosuppressive medications.
02/2014 - Present Gastroenterology Nutritionist Program: Coordinated with Froedtert hospital for nutritionist support in the GI clinic to help manage our IBD, Celiac Disease, Irritable Bowel Syndrome patients.
01/04/2015 - Present Development of IBD Program ADIET Program: Comprehensive program aimed at improving patient satisfaction of all patients in the Inflammatory Bowel Disease Program
03/01/2015 - Present IBD Program Promotional Development: Work with Medical College Physicians, Froedtert Hospital and the Medical College of Wisconsin to promote the Inflammatory Bowel Disease Program
 
 
COMMUNITY SERVICE ACTIVITIES:
05/2009 - Present Crohn's and Colitis "Take Steps" Walk to raise money for IBD research. Once yearly fundraising walk - participant and fundraiser.
01/04/2011 - Present St. Jude's the Apostle Winterfest, yearly, Church festival volunteer.
06/01/2011 - 07/30/2012 Mentor Community Nurse Practitioner Anne Nohl in volunteer Research project. "Autonomic Dysfunction and Inflammatory Bowel Disease"
06/07/2015 - Present "Pie a GI" at the annual Crohn's and Colitis "Take Steps" Walk to raise money for IBD research. Volunteered to take cream pies in the face for patients who were high fundraisers.
01/21/2016 - Present Men of St. Jude's. Group focused on raising funds to benefit the students and community around St. Jude's the Apostle Church

UNIVERSITY OF MICHIGAN DAILY IMPROVEMENT MODEL WORKSHOP:
06/08/2015 - 06/10/2015 Workshop developed by the University of Michigan College of Engineering that seeks to deepen the understanding of the Daily Improvement Model that works to improve clinical and administrative efficiency.


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Stein DJ, Ananthakrishnan AN, Issa M, Williams JB, Beaulieu DB, Zadvornova Y, Ward A, Johnson K, Knox JF, Skaros S, Binion DG Impact of prior irregular infliximab dosing on performance of long-term infliximab maintenance therapy in Crohn's disease. Inflamm Bowel Dis. 2010 Jul;16(7):1173-9
2. Rafiee P, Stein DJ, Nelson VM, Otterson MF, Shaker R, Binion DG Thalidomide inhibits inflammatory and angiogenic activation of human intestinal microvascular endothelial cells (HIMEC). Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G167-76 PMCID: PMC2822501
3. Nguyen DM, El-Serag HB, Henderson L, Stein DJ, Bhattacharyya A, Sampliner RE. Medication usage and the risk of neoplasia in patients with Barrett's esophagus. Clin Gastroenterol Hepatol. 2009 Dec;7(12):1299-304.
4. Stein DJ, Hashem B. El-Serag, M.D., M.P.H., John Kuczynski, M.D., Jennifer R. Kramer Ph.D., M.P.H., Richard E. Sampliner, M.D. The Association of Barrett's Esophagus and Body Mass Index. Alimentary Pharmacology & Therapeutics. 2005 Nov 15;22(10):1005-10.
5. Fons ME, Stein DJ, Patel A, Ferrer MS, Ammon H, Mackinnon AC, Komorowski RA, Yan BC Extracolonic gastrointestinal tract morphologic findings in a case of pseudomembranous collagenous colitis. Ann Diagn Pathol. 2013 Jun;17(3):291-4
6. Bautista MC, Otterson MF, Zadvornova Y, Naik AS, Stein DJ, Venu N, Perera LP Surgical outcomes in the elderly with inflammatory bowel disease are similar to those in the younger population. Dig Dis Sci. 2013 Oct;58(10):2955-62
7. Perera LP, Ananthakrishnan AN, Guilday C, Remshak K, Zadvornova Y, Naik AS, Stein DJ, Massey BT Dyssynergic defecation: a treatable cause of persistent symptoms when inflammatory bowel disease is in remission. Dig Dis Sci. 2013 Dec;58(12):3600-5
 
Books, Chapters, and Reviews
1. Gastrointestinal Emergencies Third Edition. 2015. "Complications of Upper Gastrointestinal Endoscopy" Daniel J. Stein MD and Reza Shaker MD
2. Stein, DJ. Inflammatory Bowel Disease: A Point of Care Clinical Guide. Can I stop my medications now that I am feeling well? Why maintenance therapy is important at preventing recurrence in Crohn's disease. Stein, DJ (eds) Springer Publishing 2015.91-98
3. Stein DJ. Inflammatory Bowel Disease: A Point of Care Clinical Guide. Was There Something I Did to Get Inflammatory Bowel Disease? Environmental and Dietary Factors That Contribute to IBD. Stein DJ, Kanagala V (eds) Springer Publishing 2015.7-14
4. Stein DJ. Inflammatory Bowel Disease: A Point of Care Clinical Guide. Why Can't I Continue to Take My Narcotics?: The Long Term Negative Effects of Narcotics. Rage A, Stein DJ (eds) Springer Publishing 2015.129-134
5. Stein DJ. Inflammatory Bowel Disease: A Point of Care Clinical Guide. Why Can’t I Just Stay on Prednisone? The Long-Term Adverse Effects of Steroids. Schiro A, Stein DJ (eds) Springer Publishing 2015.119-128
6. Stein DJ. Inflammatory Bowel Disease: A Point of Care Clinical Guide. What Happens If I Do Nothing for My Ulcerative Colitis? The Natural History of Untreated Ulcerative Colitis. Kanagala V, Stein DJ (eds) Springer Publishing 2015.41-51
7. Inflammatory Bowel Disease: A Point of Care Clinical Guide. Stein DJ and Shaker R editors. Springer Publishing. 2015
 
Abstracts
1. S Kugathasan, Daniel J. Stein, MT Rivera, B Seetharam, DG Binion,: Plasma Transcobalamin II (TC II) is elevated in children with established, but not newly diagnosed Crohn's disease (CD): Acquired alteration in microvascular expression. Gastroenterology, 116: A755, 1999.
2. DG Binion, KS Ramanujam, PJ Fisher, S Fu, MT Rivera, Daniel J. Stein, KT Wilson,: Loss of inducible nitric oxide synthase (iNOS) expression in inflammatory bowel disease (IBD) human intestinal microvascular endothelial cells (HIMEC) underlies leukocyte hyper adhesion.Gastroenterology, 116: A668, 1999.
3. MT Rivera, PJ Fisher, Daniel J. Stein, T Condon, J Tami, WE Shanahan, CF Bennett, DG Binion. Antisense oligonucleotides, but not steroids, inhibit human intestinal microvascular endothelial cell (HIMEC) adhesion molecule expression and leukocyte binding: A novel therapeutic strategy in intestinal inflammation. Gastroenterology, 116: A669, 1999.
4. P Rafiee, PJ Fisher, Daniel J. Stein, CP Johnson, DG Binion,: ICAM-1, but not VCAM-1 expression is blocked with tyrosine phosphorylation inhibitors in activated human intestinal microvascular endothelial cells (HIMEC): Potential role of ERK and p38 MAPK. Gastroenterology, 116: A920, 1999.
5. S Kugathasan, Daniel J. Stein, RL Truitt, DG Binion,: Distinct mucosal T cell phenotypes in early and late pediatric Crohn's disease (CD): Increased naïve T cells are found in late, but not early CD. Gastroenterology, 118: A347, 2000.
6. S Kugathasan, A Taras, Daniel J. Stein, PJ Fisher, TH Lamirand, RL Truitt, DG Binion,: Infliximab binds human monocytes, but not mucosal T cells in vitro: no direct anti-T cell mechanism of action. Gastroenterology, 118: A110, 2000.
7. Daniel J. Stein, P Rafiee, A Taras, TH Lamirand, PJ Fisher, H Ogawa, GL Telford, MF Otterson, CP Johnson, Binion DG,: Thalidomide inhibits inflammatory and angiogenic activation of human intestinal microvascular endothelial cells (HIMEC). Gastroenterology, 120: A278, 2001.
8. Daniel J. Stein, R Chiou, B Houghton, G Ochuba. "An Unusual Case of Abdominal Pain and Urethritis." 2003 American College of Physicians Annual Session. San Diego, CA. April 3-5.
9. Daniel J. Stein, W Diaz-Calderon, and GL Woods. "Fibrosing Cholestatic Hepatitis: A Rare Complication After Renal Transplant." American College of Physicians - Arizona Chapter Annual Meeting. Tucson, AZ. October 1-2, 2005.
10. Daniel J. Stein, HB El-Serag, J Kuczynski, JR Kramer, and RE Sampliner. "The Association of Barrett's Esophagus and Body Mass Index." American College of Gastroenterology 70th Annual Scientific Meeting. October 30 - November 2, 2005. Honolulu, Hawaii. A587
11. Daniel J. Stein, Mazen Issa, Sue Skaros, Josh F Knox, Kathryn Lemke, Jeanne Emmons, Mary F Otterson, Ashwin N Ananthakrishnan, David G Binion. "History of interrupted infliximab dosing significantly diminishes efficacy during long-term maintenance therapy in Crohn's Disease." Gastroenterology. 134(4), Suppl 1: A-666, 2008.
12. Stein DJ, Ananthakrishnan A, Ulitsky A, Naik AS, Marn C, Sudakoff G, Otterson MF, Perera LP, Binion DG, Issa M. Pre-operative small bowel follow through detects more strictures on a per stricture analysis than CT enterography when compared to intra-operative findings in patients with Crohn's disease. American College of Gastroenterology annual meeting, San Diego, October 2009.
13. Beaulieu DB, Ananthakrishnan AN, Zadvornova Y, Stein DJ, Mepani R, Antonik SJ, Skaros S, Johnson K, Naik AS, Perera LP, Binion DG. Does Duration of Disease Impact Health Related Quality of Life (HRQoL) in Inflammatory Bowel Disease? Digestive Disease Week, Chicago, June 2009
14. Beaulieu DB, Ashwin N Ananthakrishnan, Zadvornova Y, Stein DJ, Mepani R, Antonik SJ, Skaros S, Johnson K, Naik AS, Perera LP, Binion DG. Seasonal variation in HRQoL and disease activity in patients with inflammatory bowel disease: a tertiary care center experience. Gastroenterology 2009;136(Suppl 1): M1158.
15. Daniel J. Stein, Benson T. Massey, Thangam Venkatesan, Richard Komorowski and Walter J. Hogan. Chronic Idiopathic Enterocolitis (CIE): Maintaining a Corticosteroid Free Response with Immunosuppressive Therapy. Digestive Disease Week, New Orleans, May 2010.
16. Zadvornova Y, Ashwin N Ananthakrishnan, Stein DJ, Skaros S, Johnson K, Naik AS, Perera LP, Issa M. Infliximab monotherapy vs. combined infliximab-immunomodulator therapy in ulcerative colitis. Digestive Disease Week, New Orleans, May 2010.
17. Kwiatt, James T., Stein, Daniel J., Naik, Amar S., Ananthakrishnan, Ashwin N., Perera, Lilani P. The 2009 Influenza Pandemic: Seasonal and H1N1 Influenza Vaccination Rates are Increasing in an IBD Population in 2009. Digestive Disease Week, New Orleans, May 2010.
18. Naik AS, Zadvornova Y, Issa M, Skaros S, Ward S, Ward A, Johnson K, Tyler K, Stein DJ, Perera LP, Ashwin N Ananthakrishnan. Tubular adenoma and low grade dysplasia in inflammatory bowel disease: Who is at risk? Digestive Disease Week, New Orleans, May 2010.
19. Selamawit Tarekegn, Kristin Oimoen, Yelena Zadvornova, Daniel Eastwood, Mazen Issa, Amar S. Naik, Daniel J. Stein, Nanda Venu, Lilani P. Perera Biologics Are Superior to Immunomodulators in Prevention of Post-Operative Recurrence of Crohn's Disease Digestive Disease Week 2011 Chicago, IL Mo1243 -- 2011
20. Adeeti Chiplunker, Yelena Zadvornova, Mazen Issa, Daniel J. Stein, Lilani P. Perera, Nanda Venu, Amar S. Naik Factors Associated with Repeat Hospitalizations in Inflammatory Bowel Disease Digestive Disease Week 2011 Chicago, IL. Tu1264 -- 2011
21. Amar S. Naik, Yelena Zadvornova, Sarah J. Lundeen, Daniel J. Stein, Nanda Venu, Mary F. Otterson, Mazen Issa, Lilani P. Perera Abdominal Venous Thrombosis Following Inflammatory Bowel Disease Related Surgeries While On Dalteparin Prophylaxis. Digestive Disease Week 2011 Chicago, IL Su1213 -- 2011
22. Mazen Issa, Yelena Zadvornova, Amar S. Naik, Daniel J. Stein, Nanda Venu, Lilani P. Perera High Rates of Escalation and Termination of Adalimumab Therapy and Patients Exposed to Infliximab . Digestive Disease Week 2011 Chicago, IL : Mo1226 -- 2011 AGA Poster of Distinction
23. Mazen Issa, Yelena Zadvornova, Daniel J. Stein, Nanda Venu, Lilani P. Perera1, David G. Binion, Amar S. Naik Long-Term Use of Purine Analogues in Inflammatory Bowel Disease: A Single Referral Center Experience Digestive Disease Week 2011 Chicago, IL Tu1293 -- 2011
24. Roy Liu, Kristin Oimoen, Yelena Zadvornova, Jessica Pruszynski, Amar S. Naik, Daniel J. Stein, Nanda Venu, Lilani P. Perera Advanced Age At Diagnosis Does Not Negatively Impact Health Related Quality of Life in IBD: Performance of SIBDQ in a Longterm Cohort Study: Digestive Disease Week 2011 Chicago, IL Tu1312 -- 2011
25. Agnes Libot, Mazen Issa, Yelena Zadvornova, Daniel J. Stein, Nanda Venu, Lilani P. Perera, Amar S. Naik Initial Vancomycin Monotherapy Is Associated with Higher Rates of Subsequent Clostridium Difficile Infection in Inflammatory Bowel Disease Population Digestive Disease Week 2011 Chicago, IL Oral Presentation
26. Perera LP, Zadvornova Y, Binion DG, Guilday C, Stein DJ, Naik AS, Venu N, Best K, Skaros S. Long term outcomes of crohn’s disease patients on maintenance anti-TNF-α therapy. Presented as a poster at Digestive Disease Week 2012.
27. Perera LP, Zadvornova Y, Massey BT, Guilday C, Stein DJ, Naik AS, Best K, Skaros S. Increased rate of non-melanoma skin cancer detection with screening skin exam in inflammatory bowel disease: Is it time to recommend routine dermatology care? Presented as a poster at Digestive Disease Week 2012.
28. Perera LP, Zadvornova Y, Saeian K, Guilday C, Stein DJ, Naik AS, Venu N, Best K, Skaros S. Durability of Anti TNF α therapy in Ulcerative Colitis: Switching is an Effective Strategy in a Small Subset of patients. Presented as a poster at Digestive Disease Week 2012.
29. Perera LP, Zadvornova Y, Binion D, Guilday C, Stein DJ, Naik AS, Venu N, Best K, Skaros S. 10 year performance of anti TNF biologic therapy in inflammatory bowel disease. Digestive Disease Week 2012. San Diego, CA
30. Desai P, Sharma A, Naik AS, Otterson M, Zadvornova Y, Perera L, Venu N, Stein DJ. Timing of Pre-Operative Anti-Tumor Necrosis Factor Therapy Does Not Affect Early Post-Operative Complication Rates in Inflammatory Bowel Disease Patients Undergoing Intestinal Resection. DDW 2012
31. Stein DJ, Zadvornova Y, Lin E, Naik AS, Perera LP, Venu N, Otterson MF, Binion DG. Long-Term Clinical Outcomes Following Surgery in Crohn's Disease Patients on Combination Immunosuppression: Impact of Anastomotic Reconstruction on Quality of Life and Healthcare Utilization. Digestive Disease Week 2013 Orlando, FL
32. Venu M, Dodda A, Gonzaga JE, Naik AS, Venu N, Perera LP, Stein DJ. Outcomes in IBD Patients WHO Are Exposed to a Subsequent Anti-TNF Agent Following Anti-TNF Drug Induced Lupus-Like Reaction. Digestive Disease Week 2013 Orlando, FL
33. Radigan M, Guilday C, Visotcky A, Massey BT, Stein DJ, Naik AS, Venu N, Best K, Skaros S, Perera LP. Development of Irritable Bowel Syndrome Symptoms in Quiescent Inflammatory Bowel Disease: Significant Association With Presence of Psychiatric Illness and Early Onset IBD. Digestive Disease Week 2013 Orlando, FL.
34. Guilday C, Eastwood D, Zadvornova Y, Stein DJ, Naik AS, Best K, Skaros S, Perera LP. Concomitant Use of Immunomodulator Therapy Results in Higher Serum Infliximab Levels Compared to Monotherapy Without Lowering Serum Haca Levels. Digestive Disease Week 2013 Orlando, FL.
35. Aadam AA, Saeian K, Massey BT, Stein DJ, Ashley L, Venu N, Venu M, Oh Y. Proximal Colon Retroflexion With Adult Versus Pediatric Colonoscopies. Digestive Disease Week 2013 Orlando, FL.
36. Ashir Z, Guilday C, Zadvornova Y, Stein DJ, Naik AS, Venu N, Best K, Skaros S, Saeian K, Perera LP. Mucosal Healing by Individual Anti TNF Agent in Crohn's Disease in Tertiary Care Setting. Digestive Disease Week 2013 Orlando, FL.
37. Naik AS, Zadvornova Y, Stein DJ, Shastri N, Venu M, Best K, Perera LP, Saeian K, Venu N. Factors Associated With 30 Day Re-Admission in Inflammatory Bowel Disease. Digestive Disease Week 2013 Orlando, FL.
38. Stein DJ, Zadvornova Y, Lin E, Naik AS, Perera LP, Venu N, Otterson MF, Binion DG. , Long-Term Clinical Outcomes Following Surgery in Crohn's Disease Patients on Combination Immunosuppression: Impact of Anastomotic Reconstruction on Quality of Life and Healthcare Utilization, Digestive Disease Week 2013, Orlando, FL, 5/18/2013 - 5/21/2013
39. Patel A, Zadvornova Y, Stein DJ, Naik AS, Best K, Idstein K, Massey BT, Perera LP. Anti TNF therapy in Inflammatory Bowel Disease: predictors of weight gain and development of obesity. Digestive Disease Week 2014. Chicago, IL.
40. Kanagala V, Zadvornova Y, Naik AS, Perera LP, Stein DJ. Asymptomatic Inflammatory Bowel Disease Patients with an Elevated CRP Are At Increased Risk of Hospitalization and Surgery Within Two Years of Follow up. Digestive Disease Week 2014. Chicago, IL.
41. Naik AS, Zadvornova Y, Stein DJ, Perera LP, Saeian K, Venu N. Impact of BMI on Inflammatory Bowel Disease Patients Diagnosed in Adolescence. Digestive Disease Week 2014. Chicago, IL.
42. Naik AS, Zadvornova Y, Stein DJ, Agrawal D, Venu N, Saeian K. , Impact of Adenomatous Colon Polyps on Inflammatory Bowel Disease (IBD) CRC Surveillance., Digestive Disease Week 2015, Washington DC, 5/16/2015 - 5/19/2015
43. Stein DJ, Ansari I, Cahill J, Agrawal D, Naik AS, Zadvornova Y. , The Majority of Inflammatory Bowel Disease Patients Feel That an Elimination Diet Trial Had Resulted in Disease Symptom Improvement. , Digestive Disease Week 2015, Washington DC, 5/16/2015 - 5/19/2015
44. Modiri A, Naik AS, Rizvi S, Zadvornova Y, Stein DJ. , Inflammatory Bowel Disease Patients With Solid Organ Transplants Who Require Anti-TNF Therapy Are Not at Increased Risk of Serious Infections. , Digestive Disease Week 2015, Washington DC, 5/16/2015 - 5/19/2015
45. Cahill J, Zadvornova Y, Naik AS, Agrawal D, Best K, Stein DJ, Azothioprine or 6-Mercaptopurnine Dose Does Not Effect Serum Infliximab Level or Rate of Antibody to Infliximab Formation, Digestive Disease Week 2015, Washington DC, 5/16/2015 - 5/19/2015
46. Stein DJ, Rizvi S, Modiri A, Fang T, Naik AS. , Two Case Reports of Toxic Megacolon From Clostridium difficile Infection Successfully Treated With Fecal Microbiota Therapy, Digestive Disease Week 2015, Washington DC, 5/16/2015 - 5/19/2015