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Juliana Perez Botero MD
Assistant Professor
Department of Medicine
Division of Hematology and Oncology - Medicine

Froedtert Hospital
9200 W Wisconsin Ave
Milwaukee, WI 53226

08/2003 - 06/2010 M.D. Universidad de los Andes, Bogotá, Colombia

06/2011 - 06/2014 Resident, Department of Internal Medicine, Mayo Clinic School of Graduate Medical Education, 200 First Street SW, Rochester, MN 55905
07/2014 - 06/2017 Fellow, Department of Internal Medicine, Division Hematology and Division of Oncology Medicine, Mayo Clinic School of Graduate Medical Education, 200 First Street SW, Rochester, MN 55905

10/2017 - Present Assistant Professor, Department of Medicine, The Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226

10/2017 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226

Board Certified
Issue DateExpiration
American Board of Internal Medicine
ABIM- Oncology
ABIM - Hematology
Juliana Perez Botero, Congenital/hereditary Thrombocytopenias and Thrombocytopathies. 16th Bleeding and Thrombosing Diseases Conference and Workshop. Mayo Medical Laboratories, Mayo Clinic, Rochester, 09/13/2017

Pérez J, Llinás, A, Duarte M, Ucrós G, Pharmacovigilance in patients who underwent radiosynovectomy with colloidal chromic phosphate P 32., 2th International Musculoskeletal Congress of the World Federation of Hemophilia., Dubai, United Arab Emirates, 04/2011
J Perez Botero, D Chen, MM Patnaik, Comparing the platelet ultrastructural phenotype in ANKRD26 and RUNX1 mutated thrombocytopenias, Friday Scientific Workshop on Inherited Hematopoietic Malignancies American Society of Hematology 57th Annual Meeting and Exposition, San Diego, Ca, 12/02/2016
Ho TH, Perez Botero J, Hogan WJ, Kenderian S, Gangat N, Tefferi A, Abraham RS, Nguyen P, Oliveira JL, He R, Chen D, Viswanatha D, Rodriguez V, Khan SP, Patnaik MM, Clinical Spectrum of Germline Mutations with Predisposition to Myeloid Neoplasms- 2016 World Health Organization Classification Update, American Society of Hematology 57th Annual Meeting and Exposition., San Diego, CA, 12/04/2016
Juliana Perez Botero, Diagnostic Challenges in Patients with Suspected Inherited Platelet Disorders, ISTH SSC 2018, Dublin, Ireland, 07/20/2018

Refereed Journal Publications/Original Papers
1. Go RS, Winters JL, Leung N, Murray DL, Willrich MA, Abraham RS, Amer H, Hogan WJ, Marshall AL, Sethi S, Tran CL, Chen D, Pruthi RK, Ashrani AA, Fervenza FC, Cramer CH 2nd, Rodriguez V, Wolanskyj AP, Thomé SD, Hook CC, Mayo Clinic Complement Alternative Pathway-Thrombotic Microangiopathy Disease-Oriented Group. Thrombotic Microangiopathy Care Pathway: A Consensus Statement for the Mayo Clinic Complement Alternative Pathway-Thrombotic Microangiopathy (CAP-TMA) Disease-Oriented Group. Mayo Clin Proc. 2016 09;91(9):1189-211.
2. Marshall AL, Botero JP, Ashrani AA, Pruthi RK, Heit JA, Chintakuntlawar A, Guenther JC, Patnaik MM. The Impact of Antithrombin Deficiency on Women's Reproductive Health Experiences and Healthcare Decision-Making. J Womens Health (Larchmt). 2017 12;26(12):1350-1355.
3. Perez Botero J, Coon LM, Majerus JA, Chen D, Pruthi RK. Factor IX Gene (F9) Genotyping Trends and Spectrum of Mutations Identified: A Reference Laboratory Experience. Semin Thromb Hemost. 2018 Apr;44(3):287-292.
4. McBane Ii R, Loprinzi CL, Ashrani A, Perez-Botero J, Leon Ferre RA, Henkin S, Lenz CJ, Le-Rademacher JG, Wysokinski WE. Apixaban and dalteparin in active malignancy associated venous thromboembolism. The ADAM VTE Trial. Thromb Haemost. 2017 10 05;117(10):1952-1961.
5. Perez Botero J, Warad DM, He R, Uhl CB, Tian S, Otteson GE, Barness RL, Olson MC, Gossman SC, Charlesworth JE, Nichols WL, Pruthi RK, Chen D. Comprehensive Platelet Phenotypic Laboratory Testing and Bleeding History Scoring for Diagnosis of Suspected Hereditary Platelet Disorders: A Single-Institution Experience. Am J Clin Pathol. 2017 Jul 01;148(1):23-32.
6. Perez Botero J, Majerus JA, Strege AK, Johnson RD, Chen D, Pruthi RK. Diagnostic Testing Approaches for Activated Protein C Resistance and Factor V Leiden: A Comparison of Institutional and National Provider Practices. Am J Clin Pathol. 2017 Jun 01;147(6):604-610.
7. Perez Botero J, Pruthi RK, Majerus JA, Coon LM, Uhl CB, Chen D, Patnaik MM. Practice patterns in the diagnosis of inherited platelet disorders within a single institution. Blood Coagul Fibrinolysis. 2017 Jun;28(4):303-308.
8. Perez Botero J, Ormsby WD, Ashrani AA, McBane RD 2nd, Wysokinski WE, Patnaik MM, Lewis BR, Grill DE, Pruthi RK, Heit JA. Do incident and recurrent venous thromboembolism risks truly differ between heterozygous and homozygous Factor V Leiden carriers? A retrospective cohort study. Eur J Intern Med. 2016 May;30:77-81.
9. Perez Botero J, Spoon DB, Patnaik MS, Ashrani AA, Trousdale RT, Pruthi RK. Incidence of symptomatic venous thromboembolism in patients with hemophilia undergoing joint replacement surgery: a retrospective study. Thromb Res. 2015 Jan;135(1):109-13.
10. Botero JP, Thanarajasingam G, Warsame R. Capturing and Incorporating Patient-Reported Outcomes into Clinical Trials: Practical Considerations for Clinicians. Curr Oncol Rep. 2016 10;18(10):61.
11. Jatoi A, Grudem ME, Dockter TJ, Block MS, Villasboas JC, Tan A, Deering E, Kasi PM, Mansfield AS, Botero JP, Okuno SH, Smith DR, Fields AP. A proof-of-concept trial of protein kinase C iota inhibition with auranofin for the paclitaxel-induced acute pain syndrome. Support Care Cancer. 2017 03;25(3):833-838. PMCID: PMC5269609
Editorials, Letters to Editor, Other
1. Perez Botero J, Ho TP, Rodriguez V, Khan SP, Pruthi RK, Patnaik MM. Coagulation abnormalities and haemostatic surgical outcomes in 142 patients with Noonan syndrome. Haemophilia. 2017 05;23(3):e237-e240.
2. Perez Botero J, Ho TP, Hogan WJ, Kenderian S, Gangat N, Tefferi A, Abraham RS, Nguyen P, Oliveira JL, He R, Chen D, Viswanatha D, Rodriguez V, Khan SP, Patnaik MM. Clinical spectrum and clonal evolution in germline syndromes with predisposition to myeloid neoplasms. Br J Haematol. 2018 07;182(1):141-145.
3. Perez Botero J, Rodriguez V. Primary Lymphedema and Viral Warts in GATA2 Haploinsufficiency. Mayo Clin Proc. 2017 03;92(3):482.
4. Perez Botero J, Chen D, Cousin MA, Majerus JA, Coon LM, Kruisselbrink TM, Klee EW, Lazaridis KN, Pruthi RK, Patnaik MM. Clinical characteristics and platelet phenotype in a family with RUNX1 mutated thrombocytopenia. Leuk Lymphoma. 2017 08;58(8):1963-1967.
5. Perez Botero J, Chen D, He R, Viswanatha DS, Majerus JA, Coon LM, Nguyen PL, Reichard KK, Oliveira JL, Tefferi A, Gangat N, Pruthi RK, Patnaik MM. Clinical and laboratory characteristics in congenital ANKRD26 mutation-associated thrombocytopenia: A detailed phenotypic study of a family. Platelets. 2016 Nov;27(7):712-715.
6. Perez Botero J, Patnaik MM. Delayed diagnosis of MYH-9–related disorder and the role of light microscopy in congenital macrothrombocytopenias. Blood. 2016 Apr 14;127(15):1940.
7. Perez Botero J, Patnaik MM. Fanconi Anemia-Protean Manifestations of Defective DNA Repair. Mayo Clin Proc. 2016 06;91(6):824-5.
8. Perez Botero J, Im R, Chen D, Patnaik MM. Grey platelet syndrome misdiagnosed as ITP. Br J Haematol. 2016 06;173(5):662.
9. Perez Botero J, Pruthi RK, Nichols WL, Ashrani AA, Patnaik MM. von Willebrand disease type1/type 2N compound heterozygotes: diagnostic and management challenges. Br J Haematol. 2017 03;176(6):994-997.
10. Perez Botero J, Oliveira JL, Chen D, Reichard KK, Viswanatha DS, Nguyen PL, Pruthi RK, Majerus J, Gada P, Gangat N, Tefferi A, Patnaik MM. ASXL1 mutated chronic myelomonocytic leukemia in a patient with familial thrombocytopenia secondary to germline mutation in ANKRD26. Blood Cancer J. 2015 May 22;5:e315. PMCID: PMC4476020
11. Botero JP, Pruthi RK. Refractory bleeding from intestinal angiodysplasias successfully treated with danazol in three patients with von Willebrand disease. Blood Coagul Fibrinolysis. 2013 Dec;24(8):884-6.
12. Perez J, Lucena E, Hughes M, Lizcano L, Kasper CK. Preimplantation genetic diagnosis--a historical annotation: first PGD baby turns fifteen. Haemophilia. 2011 Jul;17 Suppl 1:18-9.
13. Partain DK, Botero JP, Shi M, Poterucha JJ, Ashrani AA, Thompson CA. Spur cell anemia in the setting of progressive liver allograft failure. Am J Hematol. 2016 Oct;91(10):1061.
14. Perez Botero J, Burns D, Thompson CA, Pruthi RK. Successful treatment with thalidomide of a patient with congenital factor V deficiency and factor V inhibitor with recurrent gastrointestinal bleeding from small bowel arteriovenous malformations. Haemophilia. 2013 Jan;19(1):e59-61.
15. Sharma R, Perez Botero J, Jobe SM. Congenital Disorders of Platelet Function and Number. Pediatr Clin North Am. 2018 06;65(3):561-578.
16. Haddox CL, Carr RM, Abraham RS, Perez Botero J, Rodriguez V, Pardanani A, Patnaik MM. Phenotypic heterogeneity associated with germline haploinsufficiency: a comprehensive kindred study. Leuk Lymphoma. 2019 Jun 27:1-5.
17. McBane R 2nd, Wysokinski WE, Le-Rademacher JG, Zemla T, Ashrani A, Tafur A, Perepu U, Anderson D, Gundabolu K, Kuzma C, Perez Botero J, Leon Ferre RA, Henkin S, Lenz CJ, Houghton DE, Vishnu P, Loprinzi CL. Apixaban and Dalteparin in Active Malignancy Associated Venous Thromboembolism: The ADAM VTE Trial. J Thromb Haemost. 2019 Oct 20.

jenkins-FCD Prod-409 d1e206b0be345926047b0d9c353c78a4cce4058b