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CURRICULUM VITAE

Kevin Richard Rarick PhD
Assistant Professor
Department of Pediatrics
Division of Critical Care

OFFICE ADDRESS:
Children's Research Institute
9000 W Wisconsin Ave
Milwaukee, WI 53226

EDUCATION:
08/1996 - 05/2000 B.S., The Pennsylvania State University, State College, PA
08/2000 - 08/2001 M.S., East Stroudsburg University, East Stroudsburg, PA
08/2007 - 07/2012 Ph.D., The University of Iowa, Iowa City, IA

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
03/2007 - 08/2007 Technical Services Contractor, Military Performance Division, United States Army Research Institute of Environmental Medicine, Natick, MA 01760
09/2012 - 05/2015 Postdoctoral Fellow, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226
05/2015 - 12/2016 Research Scientist, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226

MILITARY SERVICE:
03/2002 - 03/2007 U.S. Army, United States Army Research Institute of Environmental Medicine, Natick, MA 01760

FACULTY APPOINTMENTS:
01/2017 - Present Assistant Professor, Department of Pediatrics, Division of Critical Care, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226

ADMINISTRATIVE APPOINTMENTS:
02/2017 - Present Member, Neurocritical Care Development Team, Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226
12/2018 - 05/2019 Member, Community Advisory Committee, Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226

RESEARCH ADMINISTRATIVE APPOINTMENTS:
01/2017 - Present Assistant Director of Critical Care Research, Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226
03/2017 - Present Member, Critical Care Research Operations Committee, Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226

AWARDS AND HONORS:
10/2011 - Present Public Policy Relevance Award, 12th Annual Student Interdisciplinary Health Research Poster Session, The University of Iowa
04/2012 - Present Cardiovascular Section Research Recognition Award, The American Physiological Society

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
01/2013 - Present American Physiological Society
01/2015 - Present American Heart Association

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
11/2014 - Present Present, PLOS ONE
05/2018 - Present Journal of Nerophysiology

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
Neurovascular injury detection in subarachnoid hemorrhage
Source:
Daniel M. Soref Charitable Trust
Role:
Principal Investigator
PI:
Yes
Dates:
12/04/2018 - 12/03/2019
 
Title:
Role of myeloperoxidase in reactive gliosis
Source:
MCW Neuroscience Research Center
Role:
Principal Investigator
PI:
Yes
Dates:
07/01/2019 - 06/30/2020
 
Title:
Esophago-cardiovascular reflexes following acute and chronic esophageal exposure in rats
Source:
MCW Digestive Disease Center
Role:
Multiple Principal Investigator
PI:
Yes
Dates:
07/01/2019 - 06/30/2020
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
Local
Cohen SS, Liu Q, Rarick K, and Harder D:, Gestational diabetes impairs cerebral blood flow autoregulation during the reperfusion phase following ischemia, Neuroscience Research Center Retreat, Medical College of Wisconsin, Milwaukee, WI, 05/10/2018
 
Regional
Rarick KR, Pikosky MA, Young AJ, Grediagin A, Smith TJ, Staab JS, Alemany JA, Glickman E, and Nindl BC, The insulin-like growth factor-I system during seven days of increased physical activity: comparison of sedentary versus fit individuals., 2006 New England Regional ACSM Conference, Providence, RI, 2006
Meyers N, Staricha K, Rarick K, Harder D, Cohen S, High glucose results in decreased glutamate-stimulated lactate release in astrocytes during glucose deprivation, 47th Annual Meeting of the Child Neurology Society, Chicago, IL, 10/2018
Medda BK, Rarick KR, Ryan RP, Lang IM, Harder DR, Sengupta JN, Shaker R, Strain differences in acid mediated esophago-cardiovascular reflex in rats, Digestive Disease Week 2019 Conference, Chicago, IL, 05/18/2019 - 05/21/2019
 
National
Rarick KR, Deklotz, RJ and Stauss HM, Myogenic and Baroreflex Responses Alter Blood Pressure Variability at Different Frequencies., Iowa Physiological Society 2008 Annual Meeting, Iowa City, Iowa, 2008
Rarick KR, Stauss HM, and Anderson MG, Assessment of chronic structural and functional microvascular responses to hypertension by repetitive in vivo imaging of the iris in albino rats., Iowa Physiological Society 2010 Annual Meeting, Iowa City, IA, 2010
Rarick KR, Larson DJ, Nash AL, Rotella DL, Stauss HM., Structural and functional cardiovascular responses to enhanced blood pressure variability, Iowa Physiological Society 2011 Annual Meeting, Iowa City, IA, 2011
Rarick KR, Eisenhauer JA, Harder DR, Calcium signaling and glucose response is different in adult compared to neonatal rat astrocytes., Erlanger Mini Symposium, Chattanooga, TN, 05/14/2014
Wright M, Garvin J, Liu Q, Rarick KR, Harder D, Cohen S, High glucose environment modifies astrocyte angiogenic activity: role of VEGF, Pediatric Academic Societies Meeting, San Francisco, CA, 05/2017
O'Hare C, Garvin J, Liu Q, Baack M, Rarick KR, Harder D, Cohen S, In utero hyperglycemia results in cerebral vascular remodeling in newborn rat pups, Pediatric Academic Societies Meeting, San Francisco, CA, 05/2017
Garvin J, Rarick KR, Liu Q, Harder D, Cohen S, High glucose increases astrocytic secretion of VEGF in co-culture with cerebral microvessel endothelial cells, Pediatric Academic Society Meeting, Baltimore, MD, 04/27/2019 - 04/30/2019
 
International
Staricha K, Liu Q, Rarick K, Harder D and Cohen SS, High glucose results in maladaptive astrocytic metabolic response to glucose deprivation challenge, Pediatric Academic Society Meeting, Toronto, Canada, 05/05/2018 - 05/08/2018
Kim M, Liu Q, Rarick K, Harder D and Cohen SS, Gestational diabetes results in cerebral vascular remodeling in adolescent rats, Pediatric Academic Society Meeting, Toronto, Canada, 05/05/2018 - 05/08/2018
Garvin J, Liu Q, Rarick K, Harder D and Cohen SS, High glucose decreases connexin 43 in cultured hippocampal astrocytes, Pediatric Academic Society Meeting, Toronto, Canada, 05/05/2018 - 05/08/2018
Cohen SS, Liu Q, Rarick K, and Harder D:, Gestational diabetes impairs cerebral blood flow autoregulation during the reperfusion phase following ischemia, Pediatric Academic Society Meeting, Toronto, Canada, 05/05/2018 - 05/08/2018
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Eric Yu, MCW, 06/2015 - Present (Research advisor)
Nicholas Meyer, MCW, 06/2016 - Present (Research advisor)
 
Clinical/Research Fellows
Jodi Garvin, Medical College of Wisconsin, 09/2016 - 06/2019 Scholarly Oversight Committee member
Ira Shukla, Medical College of Wisconsin, 07/2017 - Present Scholarly Oversight Committee member
Matthew Amidon, Medical College of Wisconsin, 07/2017 - Present Scholarly Oversight Committee member
Raji Venkitachalam, Medical College of Wisconsin, 07/2017 - Present Scholarly Oversight Committee member
Nital Patel, Medical College of Wisconsin, 07/2017 - 06/2019 Scholarly Oversight Committee member
Matthew Powell, Medical College of Wisconsin, 07/2017 - Present Scholarly Oversight Committee member
Whitney Kopp, Medical College of Wisconsin, 07/2017 - 06/2019 Scholarly Oversight Committee member
Samantha Friedman, Medical College of Wisconsin, 07/2017 - 06/2019 Scholarly Oversight Committee member
Palak Shah, Medical College of Wisconsin, 07/2018 - Present Scholarly Oversight Committee member
Ashwini Bhat, Medical College of Wisconsin, 07/2018 - Present Scholarly Oversight Committee member
Ali Hemyari, Medical College of Wisconsin, 07/2018 - Present Scholarly Oversight Committee member
Kellie Snooks, Medical College of Wisconsin, 07/2018 - Present Scholarly Oversight Committee member
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Graduate Students
MS Committees
Rex Chin-Hao Chen, University of Wisconsin-Milwaukee, 12/2016
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Atry F, DeLaRosa IJ, Rarick KR, Pashaie R. Design and implementation guidelines for a modular spectral-domain optical coherence tomography scanner. International Journal of Optics, vol. 2018, Article ID 3726207, 22 pages, 2018. doi:10.1155/2018/3726207.
2. Nindl BC, Alemany JA, Rarick KR, Eagle SR, Darnell ME, Allison KF, Harman EA. Differential basal and exercise-induced IGF-I system responses to resistance vs. calisthenic-based military readiness training programs. Growth Horm IGF Res. 2017 Feb 32:33-40.
3. Gebremedhin D, Zhang DX, Carver KA, Rau N, Rarick KR, Roman RJ, Harder DR. Expression of CYP 4A ω-hydroxylase and formation of 20-hydroxyeicosatetreanoic acid (20-HETE) in cultured rat brain astrocytes. Prostaglandins Other Lipid Mediat. 2016 May 9; 124:16-26.
4. Hye Khan MA, Sharma A, Rarick KR, Roman RJ, Harder DR, Imig JD. Elevated aminopeptidase P attenuates cerebral arterial responses to bradykinin in Fawn-Hooded Hypertensive rats. PLoS One. 2015 Dec 18; 10(12):e0145335.
5. Nindl BC, Pierce JR, Rarick KR, Tuckow AP, Alemany JA, Sharp MA, Kellogg MD, Patton JF. 20-hour growth hormone secretory profiles following aerobic and resistance exercise. Med Sci Sports Exerc. 2014 Oct; 46(10):1917-27.
6. Sarkar P, Zaja I, Bienengraeber M, Rarick KR, Terashvili M, Canfield S, Falck JR, Harder DR. Epoxyeicosatrienoic acids pretreatment improves amyloid β-induced mitochondrial dysfunction in cultured rat hippocampal astrocytes. Am J Physiol Heart Circ Physiol. 2014 Feb 15; 306(4):H475-84.
7. Wang L, Cossette SM, Rarick KR, Gershan J, Dwinell MB, Harder DR, Ramchandran R. Astrocytes directly influence tumor cell invasion and metastasis in vivo. PLoS One. 2013 Dec 4; 8(12):e80933.
8. Gregory SM, Spiering BA, Alemany JA, Tuckow AP, Rarick KR, Staab JS, Hatfield DL, Kraemer WJ, Maresh CM, Nindl BC. Exercise-induced insulin-like growth factor I system concentrations after training in women. Med Sci Sports Exerc. 2013 Mar; 45(3):420-8.
9. Henning PC, Scofield DE, Rarick KR, Pierce JR, Staab JS, Lieberman HR, Nindl BC. Effects of acute caloric restriction compared to caloric balance on the temporal response of the IGF-I system. Metabolism. 2013 Feb; 62(2):179-87.
10. Stauss HM and Rarick KR. Overestimation of mean heart rate by the arithmetic average of beat- by-beat sampled heart rate values. The Open Hypertens J. 2011 Oct; 4:33-36.
11. Stauss HM, Rarick KR, Leick KM, Burkle JW, Rotella DL, Anderson MG. Noninvasive assessment of vascular structure and function in conscious rats based on in vivo imaging of the albino iris. Am J Physiol Regul Integr Comp Physiol. 2011 Jun; 300(6):R1333-43.
12. Scofield DE, McClung HL, McClung JP, Kraemer WJ, Rarick KR, Pierce JR, Cloutier GJ, Fielding RA, Matheny RW Jr, Young AJ, Nindl BC. A novel, noninvasive transdermal fluid sampling methodology: IGF-I measurement following exercise. Am J Physiol Regul Integr Comp Physiol. 2011 Jun; 300(6):R1326-32.
13. Bhatia V, Rarick KR, Stauss HM. Effect of the data sampling rate on accuracy of indices for heart rate and blood pressure variability and baroreflex function in resting rats and mice. Physiol Meas. 2010 Sep; 31(9):1185-201.
14. Nindl BC, Alemany JA, Tuckow AP, Rarick KR, Staab JS, Kraemer WJ, Maresh CM, Spiering BA, Hatfield DL, Flyvbjerg A, Frystyk J. Circulating bioactive and immunoreactive IGF-I remain stable in women, despite physical fitness improvements after 8 weeks of resistance, aerobic, and combined exercise training. J Appl Physiol. 2010 Jul; 109(1):112-20.
15. Stauss HM, Rarick KR, Deklotz RJ, Sheriff DD. Frequency response characteristics of whole body autoregulation of blood flow in rats. Am J Physiol Heart Circ Physiol. 2009 May; 296(5):H1607-16.
16. Pierce JR, Tuckow AP, Alemany JA, Rarick KR, Staab JS, Harman EA, Nindl BC. Effects of acute and chronic exercise on disulfide-linked growth hormone variants. Med Sci Sports Exerc. 2009 Mar; 41(3):581-7.
17. Rarick KR, Pikosky MA, Grediagin A, Smith TJ, Glickman EL, Alemany JA, Staab JS, Young AJ, Nindl BC. Energy flux, more so than energy balance, protein intake, or fitness level, influences insulin-like growth factor-I system responses during 7 days of increased physical activity. J Appl Physiol. 2007 Nov; 103(5):1613-21.
18. Tuckow AP, Rarick KR, Kraemer WJ, Marx JO, Hymer WC, Nindl BC. Nocturnal growth hormone secretory dynamics are altered after resistance exercise: deconvolution analysis of 12-hour immunofunctional and immunoreactive isoforms. Am J Physiol Regul Integr Comp Physiol. 2006 Dec; 291(6):R1749-55.
19. Nindl BC, Tuckow AP, Alemany JA, Harman EA, Rarick KR, Staab JS, Faupel ML, Khosravi MJ. Minimally invasive sampling of transdermal body fluid for the purpose of measuring insulin-like growth factor-I during exercise training. Diabetes Technol Ther. 2006 Apr; 8(2):244-52.
20. Nindl BC, Rarick KR, Castellani JW, Tuckow AP, Patton JF, Young AJ, Montain SJ. Altered secretion of growth hormone and luteinizing hormone after 84 h of sustained physical exertion superimposed on caloric and sleep restriction. J Appl Physiol. 2006 Jan; 100(1):120-8.
21. Cohen S, Liu Q, Wright M, Garvin J, Rarick K, Harder D. High glucose conditioned neonatal astrocytes results in impaired mitogenic activity in cerebral microvessel endothelial cells in co-culture. Heliyon. 2019 May 23;5(5):e01795. doi: 10.1016/j.heliyon.2019.e01795.
22. Nindl BC, Eagle SR, Matheny RW Jr, Martin BJ, Rarick KR, Pierce JR, Sharp MA, Kellogg MD, Patton JF. Characterization of growth hormone disulfide-linked molecular isoforms during post-exercise release vs nocturnal pulsatile release reveals similar milieu composition. Growth Horm IGF Res. 2018 Oct - Dec;42-43:102-107.
23. Gong X, Hou Z, Endsley MP, Gronseth EI, Rarick KR, Jorns JM, Yang Q, Du Z, Yan K, Bordas ML, Gershan J, Deepak P, Geethadevi A, Chaluvally-Raghavan P, Fan Y, Harder DR, Ramchandran R, Wang L. Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes. NPJ Precis Oncol. 2019;3:24. PMCID: PMC6776663
 
Books, Chapters, and Reviews
1. Harder DR, Rarick KR, Gebremedhin D. Regulation of Cerebral Blood Flow: Response to Lipid Mediators. Comprehensive Physiology, in press January 2018.
 
Abstracts
1. Rarick KR, Nindl BC, Castellani JW, Tuckow AP, Young AJ, and Montain SJ. Luteinizing hormone secretion is altered after prolonged metabolic stress in men. The Physiologist, 47(4): 305, 2004.
2. Rarick KR, Tuckow AP, Alemany JA, Staab JS, Welsh TT, Sharp MA, Kellogg MD, and Nindl BC. Exercise mode and volume differentially affect growth hormone and luteinizing hormone secretion patterns. Med Sci Sports Exerc, 37(5): S352, 2005.
3. Rarick KR, Pikosky MA, Young AJ, Grediagin A, Smith TJ, Staab JS, Alemany JA, Mathow MM, Tuckow AP, Glickman E, and Nindl BC. Effect of protein intake on IGF-I system responses to a 7-day exercise-induced negative energy balance. Med Sci Sports Exerc, 38(5): 2006.
4. Rarick KR, Pikosky MA, Young AJ, Grediagin A, Smith TJ, Staab JS, Alemany JA, Glickman E, and Nindl BC. Insulin-like growth factor-I system response to increased energy flux: low versus high aerobic fitness. Med Sci Sports Exerc, 39(5):S456, 2007.
5. Rarick KR., Stauss HM, Larson DJ, Rotella DL, and Anderson MG. In vivo determination of microvascular responses to hypertension in conscious rats. FASEB J.25:681.6, 2011.
6. Rarick KR, Larson DJ, Rotella DL, Anderson MG, Stauss HM. Functional and structural vascular responses to increased blood pressure variability is frequency dependent. FASEB J. 25:818.9, 2011.
7. Rarick KR, Klepper KM, Nash AL, Rotella DL, and Stauss HM. Functional cardiovascular responses precede structural responses to enhanced blood pressure variability. FASEB J. 26:684.20, 2012.
8. Rarick KR, Ryan RP, Harder DR. Hypercapnia impairs cerebral blood flow autoregulation in conscious, unrestrained rats. FASEB J. 29:832.10, 2015
9. Yu E, Cohen S, Liu Q, Ryan R, Gebremedhin D, Harder D, Rarick KR. High glucose concentration attenuates insulin-stimulated protein kinase B levels in cultured astrocytes. FASEB J. 30:lb638, 2016.
10. Cohen S, Liu Q, Ryan R, Gebremedhin D, Harder D, Rarick KR. Change in environmental glucose concentration alters astrocytic insulin and insulin receptor levels. FASEB J. 30:lb632, 2016.
11. Banerjee B, Zhang J, Medda B, Rarick KR, Ryan R, Harder D, Shaker R. Effect of early-in life esophageal acid exposures on mitochondrial morphology and expression in anterior cingulate cortex neurons in rats. Gastroenterology. 152:S926-S927, 2017.
12. Rarick KR, Medda B, Ryan R, Lang, I, Harder D, Shaker R. Cardiovascular responses to acute and chronic esophageal acid exposure in rats; description of an acid mediated esophago-cardiovascular reflex. Gastroenterology. 154:S473, 2018.
13. Rarick KR, Eisenhauer JA, Harder DR. Calcium signaling and glucose response is different in adult compared to neonatal rat astrocytes. FASEB J. 28:1177.7, 2014.
 

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