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CURRICULUM VITAE

Margaret Mary Samyn MD
Professor
Department of Pediatrics
Division of Cardiology

OFFICE ADDRESS:
Children's Hospital
9000 W Wisconsin Ave
Milwaukee, WI 53226

EDUCATION:
09/1977 - 05/1981 Marian High School, Birmingham, MI
08/1981 - 05/1985 BS, University of Detroit, Detroit, MI
08/1985 - 05/1989 MD, Wayne State University, Detroit, MI

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
1986 Surgical Externship, Pediatric Externship, St Joseph Mercy Hospital, Ann Arbor, MI
1989 Oncology Externship, University of Nottingham, England
1989 - 1990 Internship, Pediatrics/Internal Medicine, University of Michigan
1990 - 1992 Residency, Pediatrics, University of Michigan, Ann Arbor, MI
1994 - 1997 Fellowship, Pediatric Cardiology, University of Iowa, Iowa City, IA
09/1997 - 05/2000 Parke – Davis/ Warner Lambert Pharmaceutical Research, 2800 Plymouth Rd, Ann Arbor, MI 48105
05/2000 - 01/2001 Director of Clinical Research, Project: Pediatric Drug Development for Cardiology, Pfizer Global Research & Development, 2800 Plymouth Road, Ann Arbor, MI 48105
02/2001 - 09/2002 Director, Experimental Medicine, Cardiovascular Research projects in hypertension, dyslipidemia, atherosclerosis, and thrombosis, Pfizer Global Research & Development, 2800 Plymouth Road, Ann Arbor, MI 48105
07/2003 - 09/2003 Cardiac MRI Training, Harvard Medical School, Children’s Hospital Boston
01/2014 - 04/2014 Executive Education: Leadership from Analysis to Action, Stanford University, 450 Serra Mall, Stanford, CA 94305

FACULTY APPOINTMENTS:
07/1992 - 06/1994 Child Health Associates, Eisenhower Pkwy, Private Practice Pediatrics, Ann Arbor, MI
07/1992 - 06/1994 Clinical Associate, Department of Pediatrics, University of Michigan, Ann Arbor, MI
09/1997 - 03/2003 Adjunct Assistant Professor, Pediatric Cardiology, University of Michigan, Ann Arbor, MI
04/2003 - 07/2006 Associate Professor, Pediatric Cardiology, Director Pediatric Cardiac MRI, University of Florida, Gainesville, FL
08/2006 - 05/2012 Associate Professor, Pediatric Cardiology, Director, Cardiac MRI Research, Herma Heart Center, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI
02/2011 - Present Adjunct Associate Professor, Biomedical Engineering Department, Marquette University, Milwaukee, WI
07/2012 - Present Professor, Pediatrics, Cardiology, Medical College of Wisconsin, Milwaukee, WI

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
2012 - 2013 Interview of Internship Candidates, Medical College of Wisconsin, Milwaukee, WI 53226
2015 - Present Grant Writting for Foundations Course, Medical College Of Wisconsin, Milwaukee, WI 53226
04/10/2018 12th Annual Fellow/Resident Poster Session Judge, Medical College of Wisconsin, Milwaukee, WI 53226

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
04/2003 - 07/2006 Director, Pediatric MRI, University of Florida, Gainesville, FL
04/2003 - 07/2006 Director, Pediatric Cardiac Prevention Clinic, University of Florida, Gainesville, FL

RESEARCH ADMINISTRATIVE APPOINTMENTS:
08/2007 - 2014 Director, Cardiac MRI Research, Herma Heart Center, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:
07/1992 - 06/1994 Clinical Privileges, Newborn Associates, St. Joseph Mercy Hospital, Ann Arbor, MI
07/1992 - 06/1994 Clinical Associate, Department of Pediatrics, University of Michigan, Ann Arbor, MI
09/1997 - 12/2003 Adjunct Assistant Professor, Department of Pediatrics, Division of Pediatric Cardiology, University of Michigan, Ann Arbor, MI
1998 - 1999 Clinical Privileges, Pediatric Associates of Troy, Troy, MI
04/2003 - 07/2006 Associate Professor, Department of Pediatrics, Division of Pediatric Cardiology, University of Florida & Shands Hospital, Gainesville, FL
12/2003 - 07/2006 Joint Appointment, Radiology, University of Florida Health Sciences Center, FL
01/2004 - 07/2006 Staff Privileges, Wolfson Children’s Hospital & Baptist Health Center, Jacksonville, FL
08/2006 - Present Children’s Hospital of Wisconsin, Milwaukee, WI
07/2007 - Present Wheaton Franciscan Healthcare, St. Joseph's Hospital, 5000 W. Chambers, Milwaukee, WI 53210
2007 - Present Columbia St Mary’s Hospital, 2025 E Newport Avenue, Milwaukee, WI 53211
2007 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226
06/2010 - 03/2017 Aurora Medical Center-Summit, 2350 Summit Avenue, Oconomowoc, WI 53066
2010 - Present Bellin Health, 744 South Webster Avenue, Green Bay, WI 54305
11/2011 - Present Telemedicine, Pediatric Cardiology, St. Vincent Hospital, Green Bay, WI
04/2012 - 03/2017 Telemedicine Staff Member, Cardiovascular & Critical Care Medicine, Aurora Baycare Medical Center, Green Bay, WI
05/23/2013 - Present Courtesy Staff, Specialty Medicine, Pediatric Cardiology, Waukesha Memorial Hospital, 725 American Avenue, Waukesha, WI 53188
2013 - 12/2018 Associate, Aurora Sinai / West Allis Medical Center, Milwaukee, WI

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Pediatrics
1992
None
American Board of Pediatrics - Cardiology
08/2000
None
 
Certificates
Issued By Issue DateExpiration
BLS
AHA
02/19/2008
03/2019
PALS
AHA
02/19/2008
03/2019
 

Licensure
Number Issue DateExpiration
Michigan License
4301054417
06/16/1992
01/31/2020
Iowa License (expired)
30060
07/11/1994
07/31/2011
Florida License (expired)
ME 92658
02/18/2005
01/31/2011
Wisconsin License
49532-020
07/26/2006
10/31/2019
Illinois License (expired)
036.117589
2007
07/31/2017
 

AWARDS AND HONORS:
1981 - 1985 Trustees Scholarships, University of Detroit
1981 Chemistry, Biology, and French Awards, University of Detroit
1983 - 1984 Leo D. Cline Scholarship
1985 Phi Beta Kappa
1985 Alpha Epsilon Delta , Medical Honor Society
1985 American Chemical Society Award
1985 Chemistry, Biology and French Awards, University of Detroit
1985 Valedictorian, University of Detroit
1985 Alpha Sigma Nu , Jesuit Honor Society
1988 Alpha Omega Alpha
1989 Aesculapians , Wayne State University
1989 Distinguished Service Award, Wayne State University School of Medicine
1989 Janet M Glasgow Memorial Achievement Award (AMWA Award)
1991 Mead Johnson Award for Pediatric Research, Michigan Chapter of American Academy of Pediatrics
1994 - 1996 Fellow in Pediatric Cardiology, University of Iowa, National Institutes of Health
2009 Outstanding Medical Student Teacher Award - Evidence Based Medicine Course for M1 Students , Medical College of Wisconsin
2013 Top-Rated Doctors, Milwaukee Magazine
2015 Top-Rated Doctors, Milwaukee Magazine
2016 Top-Rated Doctors, Milwaukee Magazine

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1984 - Present Alpha Sigma Nu (National Jesuit University Honor Society) (Member)
1988 - Present Alpha Omega Alpha (Member)
1997 - Present American Academy of Pediatrics (Member)
1997 - Present American Heart Association (Member)
2001 - Present American College of Cardiology (Full Fellowship (FACC), granted autumn 2001)
2001 - Present ACC Michigan Legislative Committee (Member)
2006 - Present International Society of Magnetic Resonance in Medicine (Member)
2006 - Present Society of Cardiac Magentic Resonance Imaging (Congenital Heart Disease Group)
2007 - Present American Society of Echocardiography (Member)

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
06/2009 National Institutes of Health (NIH): SBIB-V (58) R - RFA OD-09-003 Challenge Grants Panel # 23(John Firrell, PhD Scientific Review Administrator)
2010 Grant Reviewer – Children’s Research Institute Pilot Innovative Research Grant Applications, Children’s Hospital of Wisconsin
2010 - 2011 American College of Cardiology (Abstract Reviewer)
2011 - Present Advisory Editorial Board: Pediatric Cardiology
2012 Midwest Pediatric Cardiology Society Meeting (abstract reviewer)
03/2018 Appropriate Use Multi-modality Imaging During Follow-up Care for Patients with Congenital Heart Disease, American College of Cardiology
09/2019 Reviewer, Therapeutic Accelerator Program (TAP) Research Proposals (Medical College of Wisconsin)
American Society for Gene Therapy Cardiovascular Research Abstracts
Journal of the American College of Cardiology
Journal of the American Society of Echocardiography
Annals of Internal Medicine
Journal of Pediatrics

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2001 - Present Member, Michigan Legislative Committee, ACC
08/01/2014 - 2015 Pediatric Cardiology Chief Search Committee, Medical College of Wisconsin
06/01/2015 - 05/01/2018 Representative, Faculty Affairs, Medical College of Wisconsin
08/2017 - Present Chair, Research Strategy Committee, Pediatric Cardiology, Medical College of Wisconsin
11/2017 - Present Chair, Pediatric Cardiology Fellowship Scholarship Oversight Committee, Medical College of Wisconsin
02/06/2019 - 02/09/2019 Chair, Congenital Heart Research, SCMR 22nd Annual Scientific Sessions

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
09/1997 - 05/2000 Chair, CI 1023 Clinical Development Team, Parke – Davis/ Warner Lambert
09/1997 - 05/2000 Member, CI 1023 (AdGVVEGF121 Gene Therapy) Core Development Team, Parke – Davis/ Warner Lambert
01/1998 - 05/2000 Member, CI 1023 Publication Work Group, Parke – Davis/ Warner Lambert
01/1998 - 05/2000 Member, CI 1023 Device Task Force, Parke – Davis/ Warner Lambert
2001 - 2002 Member, Global Cardiovascular Strategy Team, Pfizer Global Research & Development
2001 - 2002 Member, Ann Arbor Cardiovascular Discovery Team, Pfizer Global Research & Development
2001 - 2002 Member, Sub Team on RAM Prioritization, Pfizer Global Research & Development
2001 - 2002 Member, Sub Team on Technology Support, Pfizer Global Research & Development
2001 Chair, Sub Team on Cardiovascular Imaging, Pfizer Global Research & Development
2001 - 2002 Member, Global Cardiovascular Product Licensing Team, Pfizer Global Research & Development
2001 - 2002 Member, Sub Team on CV Strategy, Pfizer Global Research & Development
2001 - 2002 Member, Preclinical Protocol Review Committee Thrombosis Related Compounds, Pfizer Global Research & Development
2001 - 2002 Member, Ann Arbor CV New Targets Team, Pfizer Global Research & Development
2001 - 2002 Member, Pediatric Advisory Council, Pfizer Global Research & Development
2001 - 2002 Member, CV Biomarker Strategy Team, Pfizer Global Research & Development
01/2005 - 07/2006 Member, Data Safety and Monitoring Committee (DSMB) for the General Clinical Research Center (GCRC), University of Florida
2006 - Present Member, Congenital Heart Disease Sub Committee, Society of Cardiac Magnetic Resonance Imaging
2008 - 2011 Co-Chair, Pediatric Normative Data Sub Committee, Society of Cardiac Magnetic Resonance Imaging
2010 - 2017 Pediatric /Congenital Heart Steering Committee, Society of Cardiac Magnetic Resonance Imaging
04/01/2018 - 03/31/2019 Expert Panel Member, American College of Radiology (ACR) Committee on Appropriateness Criteria

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Pending
Peer Review
Title:
Cardiac Magnetic Resonance Evaluation of Cardiac Transplant
Role:
Principal investigator
Dates:
10/08/2018 - Present
 
Prior
Peer Review
Title:
Pediatric Atorvastatin in Diabetes Intervention Trial (PADIT)
Source:
NIH GCRC Grant M-01 RR 000082
Role:
Consultant
PI:
Dr. Michael Haller
Dates:
2005 - 2006
Direct Funds:
$26,445
 
Title:
Cardiac MRI Assessment of Early Atherosclerosis in Pediatric Type I and 2 (T1DM & T2DM) Diabetes
Source:
Children’s Miracle Network Grant Award
Role:
Principal Investigator
PI:
Self
Dates:
2005
Direct Funds:
$16,000
 
Title:
Pediatric Atorvastatin in Diabetes Intervention Trial (PADIT)
Source:
NIH
Role:
Consultant
PI:
Dr. Michael Haller
Dates:
2005 - 2007
Direct Funds:
$87,456
 
Title:
Cardiac Magnetic Resonance Imaging Assessment of Early Atherosclerosis in Pediatric Type 1 Diabetic, Type 2 Diabetic, and Metabolic Syndrome Patients
Source:
Children’s Research Institute, Milwaukee
Role:
Principal Investigator
PI:
Self
Dates:
2007 - 2009
Direct Funds:
$30,000
 
Title:
Quantifying Altered Hemodynamics in Response to Stenting for
Source:
NIH Subcontract, National Heart, Lung, and Blood Institute
Role:
Co-Principal Investigator
Dates:
05/15/2009 - 04/30/2011
Direct Funds:
$21,498
 
Title:
Translating Near Infrared Spectroscopy (NIRS) Oxygen Saturation Data for the Noninvasive Prediction of Spatial and Temporal Hemodynamics During Exercise
Source:
American Heart Association Midwest Affiliate Postdoctoral Fellowship
Role:
Consultant
PI:
Dr. Laura Ellwein
Dates:
07/01/2010 - 06/30/2012
Direct Funds:
$8,000
 
Title:
Optimization of Cardiovascular Magnetic Resonance Imaging in Pediatric Patients
Source:
Siemens MRI Research Agreement
Role:
Principal Investigator
Dates:
03/01/2012 - 02/28/2016
 
Title:
Characterization of the Systemic Right Ventricle for Patients with Transposition of the great arteries
Source:
NHLBI T35 grant (managed by Seema B Semovitz, MSEd, Program Manager Medical Student Summer Research Program and LCMW Associate Coordinator
Role:
Principal Investigator, mentoring summer student
Dates:
06/01/2015 - 08/14/2015
Direct Funds:
$5,000 (Stipend to fund summer student Conor Masterson M1, MCW)
 
Title:
Evaluation of Myocardial T1 Mapping and Extracellular Volume (ECV) After Pediatric Heart Transplantation: A Pilot Study
Source:
NHLBI T35 HL072483 grant (Medical Student Summer Research Program)
Role:
Mentor, MCW summer student
PI:
David R Harder PhD with coordinator Seema B. Semovitz MSEd
Dates:
06/01/2017 - 09/14/2017
Direct Funds:
$5,000 (Stipend to fund summer student Adam Gordon M2, MCW)
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
MRI Assessment of Tetralogy of Fallot, Children’s Hospital of Wisconsin Herma Heart Center Journal Club, Milwaukee, WI, 12/2006
Magnetic Resonance Imaging (CMRI): Beyond Anatomy, Cardiology Fellowship Core Lecture Cardiac, Children's Hospital of Wisconsin, 02/2007
Preventive Cardiology, Children’s Hospital of Wisconsin Fellowship Core Lecture, Milwaukee, WI, 05/2007
Clinical Research Using Cardiac Magnetic Resonance Imaging (CMRI), Children’s Hospital of Wisconsin/ Medical College of Wisconsin Grand Rounds, Milwaukee, WI, 05/2007
Cardiac Magnetic Resonance Imaging (CMRI) in Congenital Heart Disease (CHD) Patients, Children’s Hospital of Wisconsin Cardiology Fellow Lecture, Milwaukee, WI, 08/2007
Premature Atherosclerosis Associated with Systemic Lupus Erythematosis (SLE), Journal Club, Division of Rheumatology, Children’s Hospital of Wisconsin, Milwaukee, WI, 05/01/2008
Cardiac MRI: Flow Assessment, Lecture for Pediatric Cardiology Fellows. Herma Heart Center, Milwaukee, WI, 01/07/2009
Cardiac Magnetic Resonance Imaging (cMRI) Assessment of Early Atherosclerosis in Pediatric Type 1 Diabetic (T1DM), Type 2 Diabetic (T2DM), and Metabolic Syndrome Patients, Medical College of Wisconsin First Annual Cardiovascular Translational Research Symposium, Milwaukee, WI, 01/09/2009
Cardiac Magnetic Resonance Imaging, Marshfield Clinic, Grand Rounds, Marshfield, WI, 03/20/2009
2009 NIH Challenge Grant: Cardiac Magnet Resonance Imaging (CMR) Assessment of Early Atherosclerosis in Pediatric Patients, Herma Heart Center Cardiac Research Focus Meeting, Milwaukee, WI, 05/12/2009
Cardiac MRI of Coarctation of the Aorta, Lecture for CMR Staff and Cardiology fellows: Children’s Hospital of Wisconsin, Milwaukee, WI, 09/17/2009
Cardiac MRI: Considerations for Biomedical Engineers, Brotz Seminar Series, Marquette University Biomedical Engineering Department, Milwaukee, WI, 09/18/2009
Safe and Effective Cardiac Magnetic Resonance Imaging of Infants, Journal Review of Relevant Literature, Cardiology Case Review Meeting, Children's Hospital of Wisconsin (with Eckehard Stuth and David Hehir), 02/2010
Value of Cardiac MRI in Unique Cardiomyopathies: Arrhythmogenic Right Ventricular Dysplasia and Left Ventricular Non-compaction, Fellow Lecture, Children's Hospital of Wisconsin, 05/05/2010
Cardiac Magnetic Resonance Imaging Can Detect Early Vascular Changes in Diabetic Children, Children’s Research Institute Diabetes Symposium, Milwaukee, WI, 05/14/2010
Cardiac Magnetic Resonance Imaging Can Detect Early Vascular Changes in Diabetic Children, Herma Heart Center Grand Rounds, Milwaukee, WI, 06/02/2010
Cardiac Magnetic Resonance Imaging Can Detect Early Vascular Changes in Diabetic Children, Froedtert Hospital Cardiovascular Center Vascular Biology Affinity Working Group Meeting, Milwaukee, WI, 06/14/2010
How Does Cardiac Magnetic Resonance (CMR) Imaging Aid Management of Congenital Heart Disease?, Marquette University Department of Biomedical Engineering, Milwaukee, WI, 03/28/2011
Cardiac MRI for Assessing Left Ventrical Non-Compaction, Froedtert Hospital & Children's Hospital of Wisconsin Joint Cardiovascular Magnetic Resonance Imaging Conference, Froedtert Hospital, 03/18/2015
Utility of Magnetic Resonance Imaging in Cardiomyopathies, Fellow Lecture, Medical College of Wisconsin, 05/18/2015
Novel Application of Cardiovascular Magnetic Resonance Imaging Computational Fluid Dynamics Modeling: From Congenital Heart Disease to Acquired Heart Disease, Quality Improvement / Research Conference, Children's Hospital of Wisconsin, 11/17/2015
The State of MRI Research, Quality Improvement / Research Conference, Children's Hospital of Wisconsin, 11/22/2016
Myocardial Tissue Characterization by Cardiac Magnetic Resonance Imaging, Children's Hospital of Wisconsin, 03/07/2017
Cardiac Manifestations of Rheumatologic Diseases, Rheumatology Division Lecture, Children's Hospital of Wisconsin, 05/11/2017
Cardiac Magnetic Resonance Imaging for Diagnosis of Cardiovascular Disease, Herma Heart Institute Talk for Summer Research Students, Children's Hospital of Wisconsin, 06/12/2018
Samyn, MM; Cava, JR; Goot, B.; Gerardin, J., Cardiac MRI Research - State of the Art, QI/Research Conference, Children's Hospital of Wisconsin, Herma Heart Institute, 09/25/2018
Cardiac Magnetic Resonance Evaluation of Cardiac Tumors, QI/Research Conference, Children's Hospital of WI; Herma Heart Institute, 01/29/2019
Patel, C. and Samyn, MM, CMR Evaluation of Single Ventricle Patients, Froedtert Cardiology, 02/26/2019
Hypertension and Hyperlipidemia, Herma Heart Institute Fellow Core Conference, Children's Hospital of Wisconsin, 06/10/2019
 
Regional
William Stewart Halsted, Lecture, Surgery Conference, Historical Presentation, Harper Hospital, Wayne State University; Detroit, MI, 12/1987
Septic Shock, Lecture, Pediatrics Grand Rounds, University of Michigan, 02/1991
Children's Views of Cancer (Presentation of Work done at UCLA with Lonnie Zeltzer, M.D.), Michigan Chapter of the American Academy of Pediatrics, Traverse City, MI, 07/1991
Office Practice Cardiology, Resident Teaching Conference, University of Iowa, 11/1996
Subacute Bacterial Endocarditis, Invited Speaker, University of Iowa Dental School, 02/1997
Influence of Bicuspid Aortic Valve on Surgical Intervention for Subaortic Obstruction, Samyn MM, Burns TL, Delius RE, Behrendt DM, Invited Speaker - Midwest Pediatric Cardiology Society 21st Annual Scientific Session, Washington University School of Medicine, St. Louis, 09/1997
Gene Therapy and Cardiovascular Disease, St Joseph Mercy Hospital Grand Rounds, Ann Arbor, MI, 09/1998
Will Gene Therapy Replace CABG and TMR?, Beaumont Hospital Interventional Cardiology Symposium, Dearborn, MI, 09/1998
Hyperlipidemia and Hypertension in Children, University of Michigan Residents’ Conference, Ann Arbor, MI, 10/1998
Pediatric Preventive Cardiology, University of Michigan Residents’ Conference, Ann Arbor, MI, 11/2000
Pediatric Pharmaceutical Development: Dawning of a New Era, University of Michigan Department of Pediatric Cardiology Monday Conference, Ann Arbor, MI, 01/2002
Office Practice Cardiology East Ann Arbor Health Center, East Ann Arbor Health Center University of Michigan Department of Pediatrics, Ann Arbor, MI, 02/28/2002
Preventative Cardiology, University of Michigan Residency Program, Ann Arbor, MI, 05/09/2002
Pharmaceutical Research – Addressing the Needs of Pediatric Patients, Grand Rounds: University of Michigan Department of Pediatrics, Ann Arbor, MI, 07/23/2002
Pharmaceutical Development: Reasons to Participate, Grand Rounds: University of Iowa Hospitals and Clinics, Iowa City, IA, 10/11/2002
Childhood Obesity: Scope and Long – term Consequences, Michigan Department of Community Health Conference, Eat Healthy + Play Hard = Smart Kids, Lansing, MI, 04/15/2003
Congenital Heart Disease MRI for Radiologists, Video Conference, University of Florida, Gainesville, FL, 01/25/2006
What Should the Primary Care Practitioner Know About Cardiac MRI? MRI for Pediatric Heart Disease, Condell Medical Center Grand Rounds, Libertyville, IL, 06/17/2008
Cardiac Magnetic Resonance Imaging Can Detect Early Vascular Changes in Children with Type I Diabetes (T1DM), Samyn M, Simpson P, Widlansky M, Leibham S, Cava J, Krolikowski M, Moore S, LaDisa J, Alemzadeh R, Abstract Oral Presentation - 34th Annual Midwest Pediatric Cardiology Society Scientific Session, Indianapolis, IN, 09/24/2010
Restrictive versus Nonrestrictive Physiology Following Repair of Tetralogy of Fallot: Is there a Difference? Samyn M, Kwon E, Gorentz J, Yan K, Cava J, Simpson P, Frommelt P, Tweddell J, 2nd Annual Joint Conference on Advances in Pediatric Cardiothoracic Disease Management, Grand Traverse, MI, 09/22/2012
Impact of service learning on medical students' attitudes toward healthcare for the homeless, Spindler D, Meurer L, Diehr S, Samyn M, Family Medicine Midwest 2013 Conference, Milwaukee, WI, 10/05/2013
Novel Applications of Cardiovascular Magnetic Resonance Imaging Computational Fluid Dynamics Modeling: From Congenital Heart Disease to Acquired Heart Disease, Olin Engineering Buildling, Marquette University, 02/05/2016
Evaluation of Myocardial T1 Mapping and Extracellular Volume (ECV) After Pediatric Heart Transplantation. Gordon A, Goot B, Punnoose A. Yan K, Cava JR, Krolikowski M, Kindel S, Samyn MM, Midwest Society Meeting (presented on behalf of medical student A. Gordon), St Louis MO, 09/08/2017
 
National
Gene Therapy for Angiogenesis, Hartford Hospital 15th Annual Cardiovascular Symposium, Hartford, CT, 10/1999
Optimizing Pharmaceutical to Patient Care Center Interactions in Pediatric Recruitment, Barnett International Conference Group, Philadelphia, PA, 03/07/2002
Pediatric Clinical Trials, Barnett International Conference, Philadelphia, PA, 09/18/2002 - 09/20/2002
Pediatric Recruitment, Barnett International Conference, Philadelphia, PA, 03/10/2003 - 03/11/2003
Pediatric Congestive Heart Failure Research in the ICU Setting, Pediatric Intensive Care Unit, University of Florida, Gainesville, FL, 05/09/2003
Partnering for Expertise: Pharmaceutical Industry Collaborating with Academic Medical Centers for Successful Pediatric Trials, Barnett International Conference, Pediatric Clinical Trials, Philadelphia, PA, 11/19/2003 - 11/20/2003
Preventive Cardiology When to refer?, Pediatric Grand Rounds: University of Florida, Gainesville, FL, 12/12/2003
Pediatric Clinical Trials, Barnett International Conference, Philadelphia, PA, 03/31/2004 - 04/01/2004
Preventive Cardiology, Fellows Conference, University of Florida, 05/13/2004
Congenital Heart Disease in Children and Adolescents, The Osler Institute Pediatric Board Review Course and Cardiac Problems Associated with Systemic Disease, Tampa, FL, 06/02/2004
MRI Evaluation of the Right Ventricular Anatomy and Function in Tetralogy of Fallot, Southeast Pediatric Cardiology Society Meeting, Howey – in – the Hills, FL, 09/08/2004 - 09/11/2004
The Value of Cardiac MR/CT for Pediatric Cardiology, North American Society of Cardiac Imaging, Amelia Island, FL, 10/02/2004 - 10/05/2004
Cardiac MRI/ MRA for Congenital Heart Disease, Pediatric Grand Rounds University of Florida, Gainesville, FL, 02/11/2005
Congenital Heart Disease, Medical Student Lecture. University of Florida, Gainesville, FL, 02/14/2005
Radiology Hot Seats. Pediatric Cardiac MRI – Interesting Cases, University of Florida. Hilton Hotel, Gainesville, FL, 04/23/2005 - 04/24/2005
Congenital Heart Disease in Children and Adolescents and Cardiac Problems Associated with Systemic Disease and The Pediatric Cardiovascular Physical Examination, The Osler Institute Pediatric Board Review Course, Tampa, FL, 05/22/2005
Functional Cardiac Magnetic Resonance Imaging (CMRI): Right Ventricular Evaluation in Congenital Heart Disease (CHD) Patients, North American Society of Cardiac Imaging, Amelia Island, FL, 10/10/2005
Cardiac MRI/ MRA for Congenital Heart Disease, University of Florida: MRI for Technologists, Gainesville, FL, 11/19/2005
Pediatric Cardiology as a Career, University of Florida Mentoring Conference for Pediatrics Residents, 12/01/2005
Managing and Facilitating Clinical Trial for the Pediatric Community., Marcus Evans 2nd Annual Pediatric Clinical Trials Conference, Cambridge, MA, 12/06/2005
“Radiology Hot Seats.” “Cardiac MRI for Congenital Heart Disease.”, Radiology Board Review Courses, University of Florida, Gainesville, FL, 04/05/2006 - 04/09/2006
Radiology Hot Seats and Cardiac MRI for Congenital Heart Disease, Radiology Board Review Courses, University of Florida, Gainesville, FL, 04/26/2006 - 04/30/2006
Adult Congenital Heart Disease: MRI versus Echocardiography, Echocardiography Conference for Technologists, University of Florida, 04/29/2006
Cardiac Magnetic Resonance Imaging (cMRI) Assessment of Early Atherosclerosis in Pediatric Type 1 Diabetic (T1DM), Type 2 Diabetic (T2DM), and Metabolic Syndrome, Children’s Hospital of Philadelphia/ University of Pennsylvania, Guest of Drs Mark Fogel & Robert Shaddy, Children's Hospital of Philadelphia, 11/2008
Ventricular Volumes: How to Get and How to Interpret Them (Pediatric CMR Tools Session), Society for Cardiovascular Magnetic Resonance (SCMR) 16th Annual Scientific Sessions, San Francisco, California, 01/30/2013 - 02/03/2013
Translating near-infrared spectroscopy O2 saturation data for the non-invasive prediction of spatial and temporal hemodynamics during exercise, Ellwein L, Samyn M, Danduran M, Schindler-Ivens S, Leibham S, Ladisa JF, Jr, Society of Mathematical Biology Annual Meeting, Atlanta, GA, 2015
Moderator: Pediatric/ Congenital Heart Collaborative Research Meeting., Society for Cardiovascular Magnetic Resonance (SCMR) 22nd Annual Meeting., Bellevue Washington, 02/08/2019
CMR Evaluation of Cardiac Tumors in Children, Society of Cardiovascular Magnetic Resonance (SCMR), Seattle, WA, 02/2019
 
International
MRI Assessment of the Single Ventricle, Society for Cardiac Magnetic Resonance (SCMR) Scientific Sessions, Nice, France, 02/05/2011
Ventricular Function: Acquisition and Interpretation, Society for Cardiac Magnetic Resonance (SCMR) Scientific, Nice, France, 02/05/2015
Evaluation of Myocardial T1 Mapping and Extracellular Volume (ECV) After Pediatric Heart Transplantation. Adam Gordon BS, Ann Punnoose MD, Ke Yan PhD, Benjamin Goot MD, Joseph R Cava MD PhD, Mary Krolikowski MS, Steve Kindel MD, and Margaret M Samyn MD, The Joint EuroCMR*/SCMR Meeting, Barcelona, Spain, 01/31/2018 - 02/02/2018
 

COMMITTEE SERVICE:
Medical College
2004 - 2006 Member, Data Safety and Monitoring Committee General Clinical Research Center, University of Florida
2006 - 2007 Member, Quality Improvement Project Coordinator for Fellows, Medical College of Wisconsin
2006 - 2008 Member, Pediatric Resident Interview, Medical College of Wisconsin
2007 - 2008 Member, CSG Quality Service Committee, Medical College of Wisconsin
2007 Member, Consultation Guideline Subcommittee, CSG Quality Service, Medical College of Wisconsin
2007 - 2010 Member, Advisor Program for Pediatric Interns, Medical College of Wisconsin
2009 - 2010 Member, Parliamentary Committee, Children’s Hospital of Wisconsin
2010 Member, Clinical Effectiveness Research Task Force, Children’s Hospital of Wisconsin
2010 - Present Member, Credentials Committee, Children’s Hospital of Wisconsin
2012 Member, Intern Selection, Medical College of Wisconsin/Children's Hospital of Wisconsin
08/01/2014 - Present Member, Search Committee, Pediatric Cardiology, Medical College of Wisconsin
2014 - 05/2015 Alternate, Faculty Council, Medical College of Wisconsin
06/01/2015 - 05/01/2018 Representative, Faculty Council, Medical College of Wisconsin
06/2018 Reviewer, Therapeutic Accelerator Program (TAP) Research Proposals, Drug Discovery Center/ Department of Pharmacology & Toxicology, Medical College of Wisconsin
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
01/2009 - 05/2009 Instructor for Medical College of Wisconsin Course CC 002 Foundations of Evidence Based Medicine
09/2009 - 11/2009 Instructor for Course CC002 Foundations of Evidence Based Medicine (Course Director: Linda Meurer, MD Department of Family Medicine)
10/27/2010 Case Based Discussion 2 at Medical College of Wisconsin: Atherosclerosis in Diabetes with Dr Jung-JA Kim (Biochemistry faculty)
07/2013 - 06/2014 Phoebe Jensen (M1) - Mentor
09/01/2013 Lecturer for M2 Class, Cardiovascular Modules, Tetrlogy of Fallot
10/17/2014 Lecturer for M2 Class, Cardiovascular Modules, Tetrlogy of Fallot
10/17/2016 Lecturer for M2 Class, Cardiovascular Modules, Tetrlogy of Fallot
 

EXTRAMURAL TEACHING:
Medical Student Education
08/2006 - Present Medical College of Wisconsin, Active in teaching medical students on the cardiology inpatient (4th floor ward) and outpatient cardiology clinic
05/2009 - 04/2010 Children’s Hospital of Wisconsin, General Pediatric Ward Attending
09/2009 Marquette University, Invited speaker, Brotz Seminar Series, Biomedical Engineering Department. “Cardiac MRI: Considerations for Biomedical Engineers,” Milwaukee, Wisconsin
 
Resident and Fellow Education
08/2006 - Present Children’s Hospital of Wisconsin, Active in teaching radiology technicians and cardiology fellows how to perform diagnostic cardiac MRI/ MRA studies for congenital heart disease
08/2006 - Present Medical College of Wisconsin, Participate in Echocardiography Laboratory QA and case presentations/ teaching
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Karla Wehrheim, Medical College of Wisconsin, 06/2007 - 09/2007 Research mentor for MCW summer student Project: Retrospective review of the management of pediatric and young adult patients with aortic valve regurgitation
Angela Schnell, Medical College of Wisconsin, 06/2008 - 09/2008 Research mentor for MCW summer student: Retrospective review of clinical status of post operative patients with systemic right ventricle: "The systemic right ventricle: Are atrial switch and Fontan patients similar?"
Derek Spindler, Medical College of Wisconsin, 06/2011 - 08/2011 Research mentor for MCW summer student Project: Retrospective review of pediatric patient characteristics and outcomes after the “New Ross”procedure for aortic regurgitation.
Derek Spindler, Medical College of Wisconsin, 2011 MCW Core Pathways Advisor
Phoebe Jensen (M1), Medical College of Wisconsin, 07/2013 - 06/2014 Mentor
Phoebe Jensen (M2), Medical College of Wisconsin, 07/2014 - 06/2015 Clinical Apprenticeship
Daniel Lee (M3), Medical College of Wisconsin, 2014 Mentor
Conor Masterson (M1), Medical College of Wisconsin, 2014 - 2018 Mentor Physician Scientist MCW Pathway and 2015 summer research mentor - Transposition of Great Arteries Project
Kristi Weinmeister (M1), Medical College of Wisconsin, 01/2015 - 04/2015 Clinical Apprentiship
Adam Gordon (M2), Medical College of WI, 06/2017 - 05/2018, Mentor Physician Scientist MCW Pathway and 2017 summer research mentor - CMR for Cardiac Allograft Assessment
Madeline Bireley, Medical College of Wisconsin, 06/2018 - Present Pathways student
 
Clinical/Research Fellows
Shelby Kutty, MD, Medical College of Wisconsin, 09/2006 - 06/2007 Outpatient cardiology clinic mentor
Jennifer Co-Vu, Medical College of Wisconsin, 08/2007 - 09/2009 Research mentor for prospective MRI study of early atherosclerosis in at-risk pediatric populations
Elena Kwon, MD, Medical College of Wisconsin, 08/2007 - 06/2010 Research Mentor
Elena Kwon, MD, Medical College of Wisconsin, 2007 - 2010 MCW Cardiology Fellow Scholarship Oversight Committee Member
David Saudek, MD, Medical College of Wisconsin, 07/2008 - 06/2009 MRI Mentor for 4th year imaging fellowship
Joseph Camarda, MD, Medical College of Wisconsin, 2008 - 2011 MCW Cardiology Fellow Scholarship Oversight Committee Member
Joseph Camarda, MD, Medical College of Wisconsin, 03/2009 - 2012 Research mentor for study of aortic flow characteristics in Marfan patients
Joseph Camarda, MD, Medical College of Wisconsin, 07/2012 - 06/2013 Mentor - 4th year imaging fellowship
Daniel Cox, MD, Medical College of Wisconsin, 07/2013 - 06/2014 Scholarship Oversight Committee Member
Garick Hill, MD, Medical College of Wisconsin, 07/2013 - 06/2014 Mentor - 4th year imaging fellowship
Chad Mackman, MD, Medical College of Wisconsin, 2013 - 2014 Mentor for case series of cor triatriatum dexter patients
Christen Chamberland, MD, Medical College of Wisconsin, 07/2014 - 06/2015 Mentor - 4th year imaging fellowship
Mamata Eagam, MD, Medical College of Wisconsin, 07/2014 - 06/2014 Scholarship Oversight Committee Member
Karla Wehrheim, MD, Medical College of Wisconsin, 07/01/2016 - 06/30/2017 Mentor - 4th year Pediatric Cardiology Imaging Fellow
Margaret Keane, MD, Medical College of WI, 07/01/2016 - 06/30/2018 Clinical mentor / research mentor - CMR for VVI
Shagun Sachdeva, MD, Medical College of Wisconsin, 07/01/2017 - 06/30/2017 4th year imaging fellowship MRI mentor
 
Residents
Laura Norton, MD, Medical College of Wisconsin, 2007 - 2010 Resident Advisor
Tan Wyllie, MD, Medical College of Wisconsin, 2008 - 2011 Resident Advisor
Steffany Moen, MD, Medical College of Wisconsin, 2010 - 2012 Resident Advisor
Keowa Bonilla, MD, Medical College of Wisconsin, 2014 - 2015 Resident Advisor
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
Graduate Students
PhD Students Advised
David Wendell, BS, Marquette University, 2008 - 2011 Biomedical Engineering PhD Advisory Committee Member Project: "Incorporating the Aortic Valve in Computational Fluid Dynamic Models Using Phase Contrast Magnetic Resonance Imaging and Valve Tracking"
Arjun Menon, Marquette University, 2011 - 05/2012 Biomedical Engineering PhD Advisory Committee Member Project: Computational fluid dynamics modeling for a rabbit model of aortic coarctation
MS Students Advised
Ronak Dholakia, Marquette University, 2009 - 2010 Biomedical Engineering Masters Thesis Committee Member Project: “Numerical Modeling of Hemodynamics in the Thoracic Aorta and Alterations by Dacron Patch Treatment of Aortic Coarctation”)
Sung Kwon, Marquette University, 05/2011 - 06/2012 Biomedical Engineering Masters Thesis Committee Member
 
Postdoctoral Students
Laura Ellwein, PhD, Marquette University, 2009 - 2012 Consultant for American Heart Association Midwest Affiliate Grant: "Near Infrared Spectroscopy (NIRS) as a Measure of Vascular Dynamics duirng Exercise, and its Use in Computational Fluid Dynamic (CFD) Modeling", awarded May 2010
 
Clinical/Research Fellows
Nisha Surenderanath, MD, University of Florida, 2004 - 2006 Pediatric Cardiology, Research Mentor
Michael Haller, MD, University of Florida, 2004 - 2006 NIH Grant Mentor Pediatric Endocrinology Fellow
Faris Al-Mousily, MD, University of Florida, 2004 - 2006 Pediatric Cardiology Fellow, MRI and Research Mentor
 

PROGRAMMATIC DEVELOPMENTS:
 
 
Clinical Programs
2004 - 2006 Cardiac Prevention Program, University of Florida Gainesville
2004 - 2006 Cardiac MRI Program, University of Florida Gainesville
 
 

COMMUNITY SERVICE ACTIVITIES:
1998 - Present Founding Member Operation Smile Southeastern Michigan Chapter
1999 - 2003 Annual Speaker for Explorathon: Career Symposium for Southeastern Michigan High School Students Workshop: “And the Beat Goes On: Pediatric Cardiology"
1999 - 2002 St Vincent de Paul Society: Thanksgiving Meals for the Needy, Pontiac, Michigan
2000 - 2002 AMWA Mentorship Program, University of Michigan Medical School
2000 - 2002 Biology Advisory Committee, University of Detroit Mercy
2001 - 2002 Instructor: Catechism St Francis of Assisi Parish – First grade class
2001 - 2003 American College of Cardiology Michigan Legislative Committee member
04/2005 Boggy Creek Heart Camp, Parents’ Weekend Volunteer
2005 - 2006 American Heart Association, Florida Chapter, Community Board member
08/2008 Children’s Hospital of Wisconsin, Herma Heart Center Annual Zoo Picnic
05/22/2010 David A. Lewis Family Education Day, “Ask the Experts” panel member
 

EMPLOYMENT:
09/1997 - 05/2000 Parke - Davis/Warner Lambert 2800 Plymouth Road Ann Arbor, MI 48105 Director of Clinical Research, Cardiovascular. Project: Gene Therapy for Angiogenesis (CI 1023) AD GV VEGF 121
05/2000 - 03/2003 Pfizer Global Research & Development 2800 Plymouth Road; Ann Arbor, MI 48105
2000 - 2003 Director of Clinical Research Projectc: Pediatric Drug Development for Cardiology
02/2001 - 09/2002 Pfizer: Director, Experimental Medicine (Clinical Sciences). Projects: Cardiovascular research including projects in hypertension, dyslipidemia, atherosclerosis, and thrombosis; Cardiac imaging & soluble biomarker research.

FDA / NIH ACCEPTED PHARMACEUTICAL INDUSTRY CLINICAL PROTOCOLS:
1999 - 2000 Protocol 1023 – 020 A Phase II, Randomized, Multicenter, 26 – Week Study to Assess the efficacy and Safety of CI 1023 Delivered Through Minimally Invasive Surgery Versus Maximal Medical Therapy in Patients with Sever Angina, Advanced Coronary Artery Disease, and No Options for Revascularization
1999 - 2000 Protocol 1023 – 005 A Double Blind, Randomized, Placebo – Controlled, Dose Ranging, 26 Week Study to Assess the safety and Efficacy of CI 1023 (AdGVVEGF 121.10) in Peripheral Arterial Disease Patients with Severe Disabling Intermittent Claudication
1999 - 2000 Protocol 1023 – 008 A Randomized, Double – Blind, Placebo Controlled, 12 Week Follow – up Pilot Study of the Tolerability and Feasibility of Administering AdGVVEGF121.10 (CI 1023) Via the Boston Scientific Corporation Scimed, Inc Endocardial Direct Injection Catheter System to Patients With Advanced Coronary Artery Disease
1999 - 2000 Protocol 1023 – 007 A Randomized, Double – Blind, Placebo Controlled, 12 Week Follow – up Study of AdGVVEGF121.10 Delivered Via the BiosenseNOGA Catheter in Coronary Artery Disease Patients with CCS Class III & IV Angina and Diffuse Disease Who Have Maximized Adequate Medical Therapy and Are Not Candidates for PTCA, CABG, or Stenting

INVESTIGATOR'S BROCHURE:
(Authored while employed at Parke – Davis Pharmaceutical Research) Herman J, Gordon D, Keiser J, Samyn M, Vartanian MA, and Whitfield L. Investigators’ Brochure for CI 1023 – AdGVVEGF 121 Issued February 25, 2000; First issued May 30, 1998.

PATENTS:
03/06/2004 WO/2004/045513 Inventors: Margaret Samyn, Milton L Pressler, Donald M. Black, Paul A Fischer, Henrik Rasmussen, Grant Yonehiro. Agent: John Kilyk of Leydig Voit & Mayer, Ltd, Chicago, IL, USA
09/01/2005 Coronary Artery Disease Treatment. USPTO Application #: 20050191278

PHARMACEUTICAL COMPANY COLLABORATIONS:
2004 Clinical Protocol Site PI: Margaret Samyn with Co-PI: F. Jay Fricker, @ University of Florida. "A multicenter, placebo-controlled, 8-month study of the effect of twice daily carvedilol in children with congestive heart failure due to systemic ventricular systolic dysfunction." Protocol 105517/321. Performed in conjunction with University of Utah and Glaxo Smith Kline.

PHARMACEUTICAL CORPORATE WHITE PAPERS:
02/2000 CI 1023 - 020 Enrollment, Parke – Davis/ Warner Lambert Pharmaceutical Research
10/2000 Preliminary Pediatric Considerations for Clinical Investigational Compounds in the Ann Arbor (Cardiovascular) Portfolio, Parke – Davis/ Warner Lambert Pharmaceutical Research
05/2001 Use of the Thrombogram in the Development of Novel Antithrombotics, Pfizer Global Research and Development

PHARMACEUTICAL INDUSTRY RESEARCH REPORTS:
08/1999 Parke – Davis/ Warner Lambert Research Report: Results as of Cutoff Date June 2, 1999, from an Ongoing Phase I Dose Ranging Study of Direct Single Administration of a Replication Deficient Adenovirus Vector Containing the VEGF 121 cDNA (AdGVVEGF121.10) (CI 1023) in a Subset of Patients With Peripheral Arterial Occlusive Disease Who Had Intermittent Claudication (Protocol 1023-002) Vartanian MA, Chartier K, Hurley C, Pak R, and Samyn M
08/1999 Parke – Davis/ Warner Lambert Research Report: Results as of Cutoff Date June 1, 1999, from an Ongoing, Single Center, Open Label, Phase I Study of Direct Single Administration of a Replication Deficient Adenovirus Vector Containing the VEGF 121 cDNA (AdGVVEGF121.10) (CI 1023) to the Ischemic Myocardium of Individuals with Life Threatening Diffuse Coronary Artery Disease After 6 Months of Follow – up (Protocol 1023-001) Kline TA, Vartanian MA, Burnett Diana, McBride S, and Samyn M
08/1999 Parke – Davis/ Warner Lambert Research Report: Results as of Cutoff Date June 2, 1999, from an Ongoing, Single Center, Open Label, Phase I Study of Direct Single Administration of a Replication Deficient Adenovirus Vector Containing the VEGF 121 cDNA (AdGVVEGF121.10) (CI 1023) to the Ischemic Myocardium of Individuals with Diffuse Coronary Artery Disease Via Minimally Invasive Surgery After 4 Weeks of Follow – up (Protocol 1023-003) Kline TA, Vartanian MA, Burnett Diana, McBride S, and Samyn M
11/1999 Parke – Davis/ Warner Lambert Research Report: Results as of Cutoff Date June 30, 1999, from an Ongoing Phase I Dose Ranging Study of Direct Single Administration of a Replication Deficient Adenovirus Vector Containing the VEGF 121 cDNA (AdGVVEGF121.10) (CI 1023) in a Subset of Patients With Peripheral Arterial Disease Who Had Rest Pain and Limb Threatening Ischemia (Protocol 1023-002) Vartanian MA, Chartier K, Hurley C, Pak R, and Samyn M
01/2000 Parke – Davis/ Warner Lambert Research Report: Results After 1 Year of Follow – up from an Ongoing, Single Center, Open-label, Phase I Study of Direct Administration of a Replication Deficient Adenovirus Vector Containing the VEGF 121 cDNA (AdGVVEGF121.10) (CI 1023) to the Ischemic Myocardium of Individuals with Life Threatening Diffuse Coronary Artery Disease (Protocol 1023-001) Khodadad TA, Isaacson JL, Vest JD, MA Vartanian, Pak R, McBride S, Hurley CC, Pressler M, and Samyn M


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Pieper DR, Samyn MM, Heverly RN. Olfactory bulbectomy prevents short photoperiod-induced anestrus in female golden hamsters. Brain Res. 1986 Aug 13;380(1):54-8.
2. Pieper DR, Samyn MM, Subramanian MG. Pituitary gonadotropin releasing hormone (GnRH) receptor levels in intact and ovariectomized-adrenalectomized female golden hamsters on a short photoperiod. Experientia. 1986 Jun 15;42(6):615-7.
3. Samyn, MM, Atkins DL, and Nazarian LF. CD ROM: Index of Suspicion, (Case Report: Pneumomediastinum) Pediatrics in Review - November 1997.
4. Samyn MM, Petershack JA, Bedell KA, Mathews MS, Segar JL. Ontogeny and regulation of cardiac AT1 and AT2 receptors during fetal life in sheep. Pediatric Research 1998 Sep; 44 (3): 323-9.
5. Delius RE, Samyn MM, Behrendt DM. Should a bicuspid aortic valve be replaced in the presence of subvalvar or supravalvar aortic stenosis? Ann Thorac Surg. 1998 Oct;66(4):1337-42.
6. Goldberg CS, Samyn MM. A method for preventive cardiology in children. Prog Pediatr Cardiol. 2001 Jan;12(2):155-160.
7. Samyn, MM. Commentary for 50 years Ago in The Journal of Pediatrics Atrial Septal Defect in Infants & Children. J Pediatrics 2004 AprilVol. 144 (4): 479.
8. Haller MJ, Samyn MM, Nichols WW, Brusko TA, Wasserfall C, Schwartz RF, Atkinson M, Shuster J, and Silverstein J. Radial Artery Tonometry Demonstrates Arterial Stiffness in Children with Type I Diabetes. Diabetes Care. 2004 Dec; 27 (12): 2911-17.
9. Samyn MM. A review of the complementary information available with cardiac magnetic resonance imaging and multi-slice computed tomography (CT) during the study of congenital heart disease. Int J Cardiovasc Imaging. 2004 Dec;20(6):569-78.
10. Chandran A, Fricker FJ, Schowengerdt KO, Cumming WA, Saidi A, Spencer CT, Paolillo J, Samyn MM. An institutional review of the value of computed tomographic angiography in the diagnosis of congenital cardiac malformations. Cardiol Young. 2005 Feb;15(1):47-51.
11. Samyn, MM. Three congenital heart case reports accepted to Society for Cardiac Magnetic Resonance (SCMR) / Medis 2006 self-assessment test. (a. Tricuspid atresia in infancy, b. partial anomalous pulmonary venous return, c. tricuspid atresia status post Fontan).
12. Janicke, D.M., Storch, E., A., Novoa, W., Silverstein, J.H., & Samyn, M.M. Assessing Barriers to Healthy Dietary Habits in Children and Adolescents: Psychometric Properties of the Pediatric Barriers to Healthy Diet Scale. Children's Health Care, 2007; 36 (2): 155-168.
13. Samyn MM, Powell AJ, Garg R, Sena L, Geva T. Range of ventricular dimensions and function by steady-state free precession cine MRI in repaired tetralogy of Fallot: right ventricular outflow tract patch vs. conduit repair. J Magn Reson Imaging. 2007 Oct;26(4):934-40.
14. Haller MJ, Stein JM, Shuster JJ, Theriaque D, Samyn MM, Pepine C, Silverstein JH. Pediatric Atorvastatin in Diabetes Trial (PADIT): a pilot study to determine the effect of atorvastatin on arterial stiffness and endothelial function in children with type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2009 Jan;22(1):65-8. PMCID: PMC3621084
15. Salm CM, Clair NE, Lustig JV, Samyn MM. Cardiac Manifestations from Non-FIP1L1-PDGFRα-Associated Hypereosinophilic Syndrome in a 13-Year-Old African American Boy. J Allergy (Cairo). 2009;2009:804910. PMCID: PMC2957620
16. Co-Vu JG, Kirkpatrick EC, Samyn MM. A rare case of hypoplastic left heart syndrome and scimitar syndrome: value of neonatal cardiac magnetic resonance imaging. Pediatr Cardiol. 2010 Jul;31(5):739-40.
17. Samyn MM, Bick D, Humphrey JA, Gandy KL. Successful congenital heart surgery for a toddler with idiopathic infantile arterial calcification. Pediatr Cardiol. 2010 Oct;31(7):1096-9.
18. Kwon EN, Mussatto K, Simpson PM, Brosig C, Nugent M, Samyn MM. Children and Adolescents with Repaired Tetralogy of Fallot Report Quality of Life Similar to Healthy Peers. Congenit Heart Dis. 2011;6:18-27.
19. LaDisa JF Jr, Dholakia RJ, Figueroa CA, Vignon-Clementel IE, Chan FP, Samyn MM, Cava JR, Taylor CA, Feinstein JA. Computational simulations demonstrate altered wall shear stress in aortic coarctation patients treated by resection with end-to-end anastomosis. Congenit Heart Dis. 2011 Sep-Oct;6(5):432-43. PMCID: PMC3208403
20. Wendell DC, Samyn MM, Cava JR, Ellwein LM, Krolikowski MM, Gandy KL, Pelech AN, Shadden SC, LaDisa JF Jr. Including aortic valve morphology in computational fluid dynamics simulations: initial findings and application to aortic coarctation. Med Eng Phys. 2013 Jun;35(6):723-35. PMCID: PMC3577975
21. Chaves AH, Cava JR, Simpson P, Hoffman GM, Samyn MM. Infant cardiac magnetic resonance imaging using oscillatory ventilation: safe and effective. Pediatr Cardiol. 2013 Jun;34(5):1201-5.
22. Samyn MM, Kwon EN, Gorentz JS, Yan K, Danduran MJ, Cava JR, Simpson PM, Frommelt PC, Tweddell JS. Restrictive versus nonrestrictive physiology following repair of tetralogy of Fallot: is there a difference? J Am Soc Echocardiogr. 2013 Jul;26(7):746-55.
23. Fratz S, Chung T, Greil GF, Samyn MM, Taylor AM, Valsangiacomo Buechel ER, Yoo SJ, Powell AJ. Guidelines and protocols for cardiovascular magnetic resonance in children and adults with congenital heart disease: SCMR expert consensus group on congenital heart disease. J Cardiovasc Magn Reson. 2013 Jun 13;15:51. PMCID: PMC3686659
24. Lee DD, Veith RL, Dimmock DP, Samyn MM. Hypertrophic cardiomyopathy: A new mutation illustrates the need for family-centered care. Pediatr Cardiol.2014 Dec;35(8):1474-7. PMID: 25182012.
25. Samyn MM, Plymale JM, Cousineau A, Tweddell J. TAPVR in a kindergartner presenting with fatigue. BMJ Case Reports 2014;Oct 09;2014.PMCID: PMC4194985.
26. Mackman CA, Liedel JL, Woods RK, Samyn MM. A case series of patients with cor triatriatum dexter: unique cause of neonatal cyanosis. Pediatr Cardiol.2015 Jan;36(1):240-3.PMID:25179457.
27. Samyn MM, Dholakia R, Wang H, Co-Vu J, Yan K, Widlansky M, LaDisa JF, Simpson P, Alemzadeh R. Cardiovascular magnetic resonance imaging based computational fluid dynamics/fluid-structure interaction pilot study to detect early vascular changes in pediatric patients with type 1 diabetes. Pediatr Cardiol. 2015 Apr: 36 (4):851-61. Doi: 1007/200246-014-1071-7 Epub 2015.Jan.11
28. Banka P, Robinson JD, Uppu SC, Harris MA, Hasbani K, Lai WW, Richmond ME, Fratz S, Jain S, Johnson TR, Maskatia SA, Lu JC, Samyn MM, Patton D, Powell AJ. Cardiac Magnetic Resonance Techniques and Findings in Children with Myocarditis: a Multi center Retrospective Study. J Cardiovasc Magn Reson. 2015 Nov 17;17:96. doi: 10.1186/s12968-015-0201-6. PMCIC:PMC4650339
29. Ellwein L, Samyn MM, Danduran M, Schindler-Ivens S, Liebham S, LaDisa JF Jr. Toward translating near-infrared spectroscopy oxygen saturation data for the non-invasive prediction of spatial and temporal hemodynamics during exercise. Biomech Model Mechanobiol. 2017 02;16(1):75-96. PMCID: PMC5217163
30. Wendell DC, Samyn MM, Cava JR, Krolikowski MM, LaDisa JF Jr. The Impact of Cardiac Motion on Aortic Valve Flow Used in Computational Simulations of the Thoracic Aorta. J Biomech Eng. 2016 09 01;138(9). PMCID: PMC4967883
31. Wendell DC, Friehs I, Samyn MM, Harmann LM, LaDisa JF Jr. Treating a 20 mm Hg gradient alleviates myocardial hypertrophy in experimental aortic coarctation. J Surg Res. 2017 10;218:194-201. PMCID: PMC5679105
32. Sharma AM, Zangwill S, Southern JF, Holland K, Geddes G, Samyn MM. Cardiac Magnetic Resonance Imaging Findings for Dilated Cardiomyopathy caused by Pathogenic Disruption of Desmoplakin Gene Influences Decision for Heart Transplantation. Annals of Pediatric Research 2017 Aug; 1 (1).
33. Rogers T, Samyn MM, Gudausky T. Electrocardiographic evidence of ischemia in a young male with anomalous origin of a coronary artery from the opposite sinus accepted for publication (June 28, 2019), Progress in Pediatric Cardiology
34. Samyn MM, Soslow J. Multi-modal Imaging of the Pediatric Heart Transplant Recipient. (Special Edition) Translational Pediatrics
35. Johnson TR, Samyn MM, Sena L. Cardiac CT and MR evaluation of the adult fontan patient Cardiac CT and MR for Adult Congenital Heart Disease. 1 November 2013;9781461488750:481-497.
36. Janicke DM, Storch EA, Novoa W, Silverstein JH, Samyn MM. The pediatric barriers to a healthy diet scale Children's Health Care. Spring 2007;36(2):155-168.
37. Goldberg CS, Samyn MM. A method for preventive cardiology in children Progress in Pediatric Cardiology. 2001;12(2):155-160.
38. Haller MJ, Samyn M, Nichols WW, Brusko T, Wasserfall C, Schwartz RF, Atkinson M, Shuster JJ, Pierce GL, Silverstein JH. Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes. Diabetes Care. 2004 Dec;27(12):2911-7.
39. Rogers TP, Samyn M, Gudausky TM. Electrocardiographic evidence of ischemia in a young male with anomalous origin of a coronary artery from the opposite sinus Progress in Pediatric Cardiology. 2019.
 
Books, Chapters, and Reviews
1. Samyn, MM. Chapter 57: Hyperlipidemia and Preventive Cardiology. Essential Pediatric Cardiology. Editors: Peter Koenig, Ziyad M. Hijazi, and Franklin H. Zimmerman. McGraw Hill, 2004.
2. Invited Author. Chapter Submitted June 2009. Saudek, D, Strasburger J, and Samyn MM. Syncope and Bradycardia. Challenging Cases in Pediatric Cardiology. W. Robert Morrow, Editor; Stuart Berger, MD, Steven Neish, MD, Robert Spicer, Associate Editors (Publication supported by the American Academy of Pediatrics), 2009.
3. Samyn MM. Tetralogy of Fallot in Clinical Decision Support: Pediatrics, edited by McMillan JM, Barrett DJ, Boney CM, Jones MD. 2013. Decision Support in Medicine, LLC. Wilmington, DE
4. Johnson TR, Sena L, Samyn MM. Chapter 21: Cardiac CT and MR Evaluation of the Adult Fontan Patient. In Cardiac CT and MR for Adult Congenital Heart Disease. Springer Science+Business Media, New York 2013.
5. Samyn MM and LaDisa JF. Novel Applications of Cardiovascular Magnetic Resonance Imaging Computational Fluid Dynamics Modeling in Congenital Heart Disease and Acquired Cardiovascular Disease in Young Patients. Magnetic Resonance Imaging. InTech. Rijeka, Croatia. ISBN 978-953-51-4829-6.
 
Abstracts
1. Samyn MM, Petershack JE, Mathews MS, Segar JL, and Robillard JE. Effects of losartan on angiotensin receptors during fetal cardiac development in sheep. Society for Pediatric Research May 1997.
2. Rajagopalan S, Shah MB, Luciano A, Lederman RJ, Samyn MM, and Nabel EG. Effect of Intramuscular Gene Transfer with VEGF121 on Lower Extremity Blood Flow in Patients with Peripheral Atherosclerotic Occlusive Disease. American College of Cardiology, March 2000.
3. Samyn MM, Garg R, Powell A, Laureen Sena L, Geva T. Range of biventricular dimensions and function evaluated by steady state free precession cine MRI in patients with repaired tetralogy of Fallot. Poster, University of Florida College of Medicine Research Day, Gainesville FL. April 2004.
4. Haller MJ, Samyn MM, Nichols W, Silverstein JH. Radial Tonometry as a Surrogate Marker for Endothelial Dysfunction in Children with Type 1 Diabetes. Poster, American Diabetes Association Meeting, June 2004.
5. Novoa W, Janicke D, Storch E, Silverstein J, and Samyn MM.. Barriers to physical activity among overweight youth. National Conference in Child Health Psychology, 2006.
6. Samyn MM, Sena L, Powell A, Garg R, Geva T. Range of biventricular dimensions and function evaluated by steady state free precession cine MRI in patients with repaired tetralogy of Fallot. Poster, International Society of Magnetic Resonance in Medicine (ISMRM), 14th Annual Scientific Session, Seattle WA. May, 2006.
7. Wehrheim K, Krolikowski M, Mussatto K, Danduran M, Cava J, Samyn MM. Retrospective review of the management of pediatric and young adult patients with aortic valve regurgitation. Poster, Midwest Pediatric Cardiology Society Meeting, St Louis MO. September 21, 2007.
8. Tomassini J, Earing MG, Bartz P, Deatsman SL, Samyn MM, Cava J, Frommelt M, Frommelt P. Assessment of RV Function in Adult Patients After Repair of Tetralogy of Fallot Using Velocity Vector Imaging: Comparison with Cardiac MRI. Oral Presentation, Midwest Pediatric Cardiology Society Meeting, St Louis MO. September 21, 2007.
9. Tommasini J, Earing MG, Bartz P, Deatsman SL, Samyn MM, Frommelt M, Frommelt PC. Velocity Vector Imaging: A Novel Technique for the Assessment of Systemic RV Function in Patients with Transposition of the Great Arteries. Oral Presentation, Midwest Pediatric Cardiology Society Meeting, St Louis MO. September 21, 2007.
10. Surenderanath N, Al-Mousily F, Theriaque D, Shuster J, Spencer C, Samyn MM. Evaluation of Aortic Valve Regurgitation by Cardiac Magnetic Resonance Imaging (CMRI): A Comparison with Echocardiogram. Poster, Society for Cardiac Magnetic Resonance (SCMR) January 2008.
11. Schnell A, Krolikowski M, Dasgupta M, Danduran M, Simpson P, Samyn MM. The systemic right ventricle: Are atrial switch and Fontan patients similar? Oral Presentation, Midwest Pediatric Cardiology Society Meeting, Minneapolis MN. September 26, 2008.
12. Dholakia R, Wendell D, Cava JR, Krolikowski M, Samyn MM, LaDisa JF. A Comparative Study of Hemodynamics in Coarctation Patients Treated with Dacron Patch Aortoplasty and Normal Subjects. Marquette University Biomedical Engineering Symposium, Milwaukee WI. March 26, 2009.
13. Wendell DC, Cava JR, Samyn MM, LaDisa JF. Incorporating the Aortic Valve into Computational Fluid Dynamic Models of Aortic Arch Geometrics Observed After Successful Repair of Aortic Coarctation. Marquette University Biomedical Engineering Symposium, Milwaukee WI. March 26, 2009.
14. Samyn MM, Saudek DE, Dasgupta M, Schnell AK, Krolikowski M, Simpson P, Cava J, and Frommelt P. Are Echocardiographic and Cardiac Magnetic Resonance Assessments Reliable and Reproducible in Patients with A Systemic Right Ventricle? Poster, American Society of Echocardiography Meeting. Washington DC. June 6 - 10, 2009.
15. Kwon EN, Yan K, Kutty S, Gorentz J, Danduran MJ, Cava JR, Simpson PM, Frommelt PC, Samyn MM. Global and Regional Right Ventricular Function and Exercise Capacity in Postoperative Tetralogy of Fallot: An Echocardiographic and Cardiac Magnetic Resonance Imaging Study. Poster American Society of Echocardiography Meeting, Washington DC. June 6 - 10, 2009.
16. Wendell DC, Cava JR, Samyn MM, LaDisa JF. Influence of Aortic Valve Morphology on Arch Hemodynamics after Successful Aortic Coarctation Repair, Poster Biomedical Engineering Society Annual Fall Meeting, Pittsburgh PA. October 7-10, 2009.
17. Kwon EN, Brosig C, Nugent ML, Simpson PM, Mussatto K, Samyn MM. Children and Adolescents with Repaired Tetralogy of Fallot Report Health-Related Quality of Life Similar to Healthy Peers, Oral, Children's Hospital of Philadelphia (CHOP) Cardiology Mtg, Orlando FL. Feb 10-14, 2010.
18. Kwon EN, Brosig C, Nugent ML, Simpson PM, Mussatto K, Samyn MM. Children and Adolescents with Repaired Tetralogy of Fallot Report Health-Related Quality of Life Similar to Healthy Peers, Oral Presentation, 3rd Annual Interdisciplinary Pediatric Behavioral Health Research Conference, Milwaukee WI. February 26, 2010.
19. Samyn MM, Simpson P, Widlansky M, Leibham S, Cava JR, Krolikowski M, Moore S, LaDisa JF, Alemzadeh R. Cardiac Magnetic Resonance Imaging Can Detect Early Vascular Changes in Children with Type 1 Diabetes (T1DM). Oral Presentation, 34th Annual Midwest Pediatric Cardiology Society Scientific Session, Indianapolis IN. September 24, 2010.
20. Camarda JA, Earing MG, LaDisa JF, Dholakia RJ, Wendell DC, Samyn MM. "Quantification of Cardiovascular Physiology Using Computational Fluid Dynamic Simulations Created From Magnetic Resonance Imaging of Marfan Patients Before and After Aortic Root Replacement. Poster, 34th Annual Midwest Pediatric Cardiology Society Scientific Session, Indianapolis IN. September 24, 2010.
21. Gandy K, Samyn MM, Simpson P, LaDisa JF. Computational Modeling of Aortic Arch Hemodynamics in Hypoplastic Left Heart Syndrome. Oral Presentation Annual Meeting of the Congenital Heart Surgeons Society (CHSS). October 24 - 25, 2010.
22. Samyn MM, Simpson P, Widlansky ME, Krolikowski M, Co-Vu JG, Ronak Dholakia R, LaDisa JF, Alemzadeh R. Cardiac magnetic resonance imaging can detect early vascular changes in children with type 1 diabetes (T1DM). Poster Presentation at Society for Cardiac Magnetic Resonance (SCMR) Scientific Sessions, Nice France. February 2011.
23. Camarda JA, Earing MG, Dholakia RJ, Kwon S, Wang H, LaDisa JF, Samyn MM. Biophysical Properties of the Aorta in Patients with Marfan Syndrome and Related Connective Tissue Disorders: Evaluation with MRI and Computational Fluid Dynamic Modeling. Poster, Society for Cardiac Magnetic Resonance (SCMR) Scientific Sessions, Nice France. February 2011.
24. Chaves A, Cava JR, Hoffman G, Simpson P, Samyn MM. Infant Cardiac MRI Using Oscillatory Ventilation: Safe and Effective. Poster, 36th Annual Midwest Pediatric Cardiology Society Scientific Session, Milwaukee WI. September 28, 2012.
25. Ellwein LM, LaDisa JF, Jr, Liebham S, Schindler-Ivens S, Samyn MM. Quantification of thoracic aorta blood flow by magnetic resonance imaging during supine cycling exercise of increasing intensity. Poster, Society for Cardiovascular Magnetic Resonance 16th Annual Scientific Sessions San Francisco, CA. January 30 - February 3, 2013.
26. Spindler D, Meurer L, Diehr S, Samyn MM. Impact of service learning on medical students' attitudes toward healthcare for the homeless. Poster, Society of Teachers of Family Medicine Annual Meeting Baltimore MD. May 1-5, 2013.
27. Banka P, Uppu S, Harris M, Hasbani K, Lai WW, Richmond ME, Fratz S, Jain S, Johnson T, Maskatia SA, Lu J, Samyn MM, Patton D, Powell AJ. Poster, CMR Techniques and Findings in Children with Myocarditis: A Multicenter Retrospective Study. 18th Annual Society of Cardiovascular Magnetic Resonance, New Orleans LA. January 16 – 19, 2014.
28. Lee DD, Veith RL, Dimmock DP, Samyn MM. Hypertrophic cardiomyopathy: A new mutation illustrates the need for family-centered care. Poster, 38th Annual Midwest Pediatric Cardiology Society Scientific Session, Ann Arbor MI. September 11-12, 2014.
29. Mackman CA, Liedel JL, Woods RK, Samyn MM. A case series of patients with cor triatriatum dexter: unique cause of neonatal cyanosis. Poster 38th Annual Midwest Pediatric Cardiology Society Scientific Session, Ann Arbor MI. September 11-12, 2014.
30. Masterson C, Saudek D, Cohen S, Slicker J, Kinney A, Krolikowski M, Samyn MM. Utility of Speckle Tracking Echocardiography in Measuring Systemic Right Ventricular Systolic Function for Patients with d-Transposition of the Great Arteries Status post Atrial Switch Procedure: A Comparison with Cardiac Magnetic Resonance Imaging. Oral presentation, Midwest Pediatric Cardiology Society Meeting, Peoria IL. September 11, 2015.
31. Masterson C, Saudek D, Cohen S, Slicker J, Kinney A, Krolikowski M, Samyn MM. Utility of Speckle Tracking Echocardiography in Measuring Systemic Right Ventricular Systolic Function for Patients with d-Transposition of the Great Arteries Status post Atrial Switch Procedure: A Comparison with Cardiac Magnetic Resonance Imaging. Poster, Society for Cardiovascular Magnetic Resonance (SCMR) Scientific Sessions, Los Angeles CA. January 27-30, 2016.
32. Samyn MM, Slicker J, Allen S, Cava JR, Goot B, Saudek D. Quality Improvement in Cardiac Magnetic Resonance Imaging. Poster, Midwest Pediatric Cardiology Society 40th Annual Meeting, Madison WI, September 15-16, 2016.
33. Singh NM, Kovach JR, Gudausky TM, Kouretas PC, Woods RK, Samyn MM. Cardiac Magnetic Resonance Imaging Aids Diagnosis for Cardiac Arrest in a Previously Healthy Child. Poster, Society for Cardiovascular Magnetic Resonance (SCMR) Scientific Sessions, Washington DC. February 1-4, 2017.
34. Gordon A, Goot B, Punnoose A, Yan K, Cava JR, Krolikowski M, Kindel S, Samyn MM. Evaluation of Myocardial T1 Mapping and Extracellular Volume (ECV) After Pediatric Heart Transplantation, Oral presentation, 41st Annual Midwest Pediatric Cardiology Society Meeting, St Louis MO, September 7-8, 2017.
35. Gordon A, Goot B, Punnoose A, Yan K, Cava JR, Krolikowski M, Kindel S, Samyn MM. Evaluation of Myocardial T1 Mapping and Extracellular Volume (ECV) After Pediatric Heart Transplantation: A Pilot Study. Society for Cardiovascular Magnetic Resonance (SCMR) Scientific Sessions, Barcelona Spain. January 31-February 3, 2018.
36. Bireley M, Kovach J, Morton C, Pan A, Nugent M, Samyn MM, Are Pacemakers Altered by Magnetic Resonance Imaging. Poster session: Feb 8, 2019 SCMR Seattle WA
37. Patel C, Ginde S, Samyn MM, Gerardin J. SCMR Oral case presentation for 4th yr fellow, C Patel Pulmonary Atresia/ Intact Ventricular Septum with Coronary Cameral Fistula: CMR Detects Myocardial Compromise
38. Patel C, Ginde S, Samyn MM, Gerardin J. Pulmonary Atresia/ Intact Ventricular Septum with Coronary Cameral Fistula: CMR Detects Myocardial Compromise. SCMR 22nd Annual Scientific Sessions. Feb 6-9, 2019 Bellevue, WA
39. Bireley M, Kovach J, Morton C, Pan A, Nugent M, Samyn MM. Are Pacemakers Altered by Magnetic Resonance Imaging? Poster presentation. SCMR 22nd Annual Scientific Sessions. Feb 6-9, 2019 Bellevue, WA
 
Non-Peer Reviewed Educational Products
1. Video Conference: “Congenital Heart Disease MRI for Radiologists” University of Florida, Gainesville. January 25, 2006
 

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