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CURRICULUM VITAE

Susanne M. Cabrera MD
Assistant Professor
Department of Pediatrics
Division of Endocrinology

OFFICE ADDRESS:
Children's Corporate Center
999 N 92 St
Milwaukee, WI 53226
Phone: 414-266-6750
Fax: 414-266-6749

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
Pediatric Endocrinology
11/13/2013
None
 
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
2011 - Present American Diabetes Association (Member)
2015 - Present American Academy of Pediatrics

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Journal Review
11/01/2014 - Present International Journal of Pediatric Endocrinology

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
2014 - 2016 Grant Reviewer, Clinical Translational Science Institute Pilot Grant
2014 - 2016 Grant Reviewer, Children's Research Institute Pilot Grant, Children's Hospital of Wisconsin

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
07/01/2015 - 06/30/2018 Member, PREP Endocrinology Board, American Academy of Pediatrics

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
TrialNet Pathway to Prevention (Natural History) Study of the Development of Type 1 Diabetes
Source:
NIDDK, NIAID, NICHD, NCRR, JDRF, ADA
Role:
Principal Investigator
PI:
Susanne M Cabrera
Dates:
07/01/2009 - Present
 
Title:
A Phase III Multicenter, Double-Blind, Randomized Placebo- Controlled Clinical Trial to Evaluate the Safety and Efficacy of MK-0431A XR (a Fixed-Dose Combination Tablet of Sitagliptin and Extended-Release Metformin) in Pediatric Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination with Insulin)
Source:
Merck Sharp & Dohme Corporation
Role:
Co-investigator
PI:
Rosanna Fiallo-Scharer
Dates:
08/20/2014 - Present
 
Title:
A 26-week open label, randomised, 2-armed, parallel group, multi-centre trial -investigating efficacy and safety of insulin detemir versus insulin Neutral Protamine Hagedorn in combination with metformin and diet/exercise on glycaemic control in children and adolescents with type 2 diabetes insufficiently controlled on metformin ± other oral antidiabetic drug(s) ± basal insulin
Source:
Novo Nordisk
Role:
Principal Investigator
PI:
Susanne Cabrera
Dates:
06/01/2015 - Present
 
Title:
Targeting Polyamines using DFMO in Persons with Type 1 Diabetes
Source:
Juvenile Diabetes Research Foundation
Role:
site investigator
PI:
Linda DiMeglio
Dates:
12/01/2015 - 12/31/2018
Direct Funds:
$1,300,000
 
Prior
Peer Review
Title:
Intestinal Permeability as a Risk Factor for Type 1 Diabetes
Source:
Children's Research Institute Pilot Innovative Research Award
Role:
PI
Dates:
04/01/2014 - 03/29/2015
Direct Funds:
$50,000
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Cabrera SM, Premature Ovarian Insufficiency, Endocrine Grand Rounds, Indiana University School of Medicine, 05/10/2010 - Present
Cabrera SM, The beta cell as therapeutic target in type 1 and type 2 diabetes, Endocrine Grand Rounds, Indiana University School of Medicine, 01/01/2011 - Present
Cabrera SM, Prediction of type 1 diabetes mellitus and prevention strategies, Department of Pediatrics Grand Rounds, Indiana University School of Medicine and Riley Hospital for Children, 07/18/2012 - Present
Cabrera SM, Current and novel prediction techniques of type 1 diabetes mellitus and on-going prevention strategies, RIP/Diabetes Journal Club, Medical College of Wisconsin, 10/02/2012 - Present
Cabrera SM, Prediction and Prevention of Type 1 Diabetes: Where we're at and where we're going, Department of Pediatrics Grand Rounds, Medical College of Wisconsin, 11/15/2012 - Present
Cabrera SM, Thyroid disease in the adolescent, Section of Adolescent Medicine Weekly Academic Conference, Medical College of Wisconsin, 02/15/2013 - Present
Susanne Cabrera, Perioperative Diabetes Management, Pediatric Surgery Basic Science Conference, Medical College of Wisconsin, 08/27/2013 - Present
Susanne M Cabrera, 5-alpha-reductase deficiency: a case report, Disorders of Sexual Development Multidisciplinary Conference, Children's Hospital of Wisconsin, 08/29/2013 - Present
 
Regional
Cabrera SM, Diabetes in the Teen, Best Practices Conference, Glacier Canyon Lodge, Wisconsin Dells, WI, USA, 03/08/2013 - Present
Cabrera SM, Clinical Trials in Type 1 Diabetes, World Diabetes Day - JDRF Southeastern Wisconsin Chapter, Blue Harbor Resort and Conference Center, Sheboygan, Wisconsin, - 11/14/2015
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
National
Monnier (CABRERA) SM, Rapid and controlled polymerization of lactide by structurally characterized ferric alkoxides, National American Chemical Society Undergraduate Symposium, San Diego, CA, USA, 10/01/2001 - Present
Cabrera SM, Behzadi JM, DiMeglio LA, and Walvoord EC, Five-year glycemic control in children with type 1 diabetes: does the type of initial education matter?, Endocrine Society National Meeting, San Francisco, CA, USA, 06/20/2008 - Present
Cabrera SM, Alvarez R, Kaefer MN, Eugster EA, and Nebesio TD, Unexpected finding of intact distal vagina in an infant with mixed gonadal dysgenesis, Endocrine Society Annual Meeting, Poster Session, San Diego, CA, USA, 06/15/2010 - Present
Cabrera SM, Tersey SA, Morris M, Nadler JL, and Mirmira RG, Combination therapy with growth-promoting and pro-differentiation agents increases beta cell mass and reduces insulitis in diabetic NOD mice., American Diabetes Association 71st Scientific Meeting, Guided Audio Tour Presentation, San Diego, CA, USA, 07/20/2011 - Present
Cabrera SM, Eugster EA, Incidence and defining characteristics of pseudoprecocious puberty in children with severe primary hypothyroidism., Pediatric Endocrine Society Meeting, Presidential Poster Session and Poster Symposium, Boston, MA, USA, 04/01/2012 - Present
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Resident and Fellow Education
2015 - Present SURFBoards Pediatric Board Preparation
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
Hyun-Hee Kim, Medical College of Wisconsin, 01/13/2014 - 05/31/2015 Clinical Advisor
 

COMMUNITY SERVICE ACTIVITIES:
2014 - Present Slam Dunk Diabetes Basketball Camp (3 day camp in West Allis, Wisconsin for children and teens with diabetes)
 


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Fisher MM, Cabrera SM, Imel EA. Successful treatment of neonatal severe hyperparathyroidism with cinacalcet in two patients. Endocrinol Diabetes Metab Case Rep. 2015;2015:150040. PMCID: PMC4496565
2. Chen YG, Cabrera SM, Jia S, Kaldunski ML, Kramer J, Cheong S, Geoffrey R, Roethle MF, Woodliff JE, Greenbaum CJ, Wang X, Hessner MJ. Molecular signatures differentiate immune states in type 1 diabetic families. Diabetes. 2014 Nov;63(11):3960-73. PMCID: PMC4207392
3. Cabrera SM, Bright GM, Frane JW, Blethen SL, Lee PA. Age of thelarche and menarche in contemporary US females: a cross-sectional analysis. J Pediatr Endocrinol Metab. 2014 Jan;27(1-2):47-51. PMCID: PMC4137967
4. Cabrera SM, Colvin SC, Tersey SA, Maier B, Nadler JL, Mirmira RG. Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes. Clin Exp Immunol. 2013 Jun;172(3):375-82. PMCID: PMC3646436
5. Cabrera SM, Rogol AD. Testosterone exposure in childhood: discerning pathology from physiology. Expert Opin Drug Saf. 2013 May;12(3):375-88.
6. Cabrera SM, Srivastava NT, Behzadi JM, Pottorff TM, Dimeglio LA, Walvoord EC. Long-term glycemic control as a result of initial education for children with new onset type 1 diabetes: does the setting matter? Diabetes Educ. 2013 Mar-Apr;39(2):187-94. PMCID: PMC4780749
7. Cabrera SM, DiMeglio LA, Eugster EA. Incidence and characteristics of pseudoprecocious puberty because of severe primary hypothyroidism. J Pediatr. 2013 Mar;162(3):637-9. PMCID: PMC4070005
8. Cabrera SM, Srivastava NT, Behzadi JM, Pottorff TM, Dimeglio LA, Walvoord EC. Long-term glycemic control as a result of initial education for children with new onset type 1 diabetes: does the setting matter? Diabetes Educ. 2013 Mar-Apr;39(2):187-94. PMCID: PMC4780749
9. Tersey SA, Nishiki Y, Templin AT, Cabrera SM, Stull ND, Colvin SC, Evans-Molina C, Rickus JL, Maier B, Mirmira RG. Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes. 2012 Apr;61(4):818-27. PMCID: PMC3314371
10. Cabrera SM, Alvarez R, Kaefer MN, Eugster EA, Nebesio TD. Unexpected finding of an intact distal vagina in an infant with mixed gonadal dysgenesis. J Pediatr Endocrinol Metab. 2011;24(9-10):831-3. PMCID: PMC4094021
11. Shull J, Monnier (CABRERA) SM, Solomon SS, Buss N, and Gerling IC. Proteome of H-411E (Liver) cells exposed to insulin and TNF-alpha: Analysis of proteins involved in insulin resistance. J Lab Clin Med 2005;145(5):275-83.
12. Solomon SS, Buss N, Shull J, Monnier S, Majumdar G, Wu J, Gerling IC. Proteome of H-411E (liver) cells exposed to insulin and tumor necrosis factor-alpha: analysis of proteins involved in insulin resistance. J Lab Clin Med. 2005 May;145(5):275-83.
13. Baruah H, Rector CL, Monnier SM, Bierbach U. Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates. Biochem Pharmacol. 2002 Jul 15;64(2):191-200.
14. Baruah H, Rector CL, Monnier(CABRERA) SM, Bierbach U. Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates. Biochem Pharmacol. 2001;64(2): 191-200.
15. O'Keefe B, Monnier (CABRERA) SM, Hillmyer M, Tolman WB. Rapid and Controlled Polymerization of Lactide by Structurally Characterized Ferric Alkoxides. J Am Chem Soc 2001;123: 339-40.
16. O'Keefe BJ, Monnier SM, Hillmyer MA, Tolman WB. Rapid and controlled polymerization of lactide by structurally characterized ferric alkoxides. J Am Chem Soc. 2001 Jan 17;123(2):339-40.
17. Cabrera SM, Wang X, Chen YG, Jia S, Kaldunski ML, Greenbaum CJ, Type 1 Diabetes TrialNet Canakinumab Study Group, Mandrup-Poulsen T, AIDA Study Group, Hessner MJ. Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset. Eur J Immunol. 2016 Apr;46(4):1030-46. PMCID: PMC4828314
18. Cabrera SM, Chen YG, Hagopian WA, Hessner MJ. Blood-based signatures in type 1 diabetes. Diabetologia. 2016 Mar;59(3):414-25. PMCID: PMC4744128
19. Henschel AM, Cabrera SM, Kaldunski ML, Jia S, Geoffrey R, Roethle MF, Lam V, Chen YG, Wang X, Salzman NH, Hessner MJ. Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility. PLoS One. 2018;13(1):e0190351. PMCID: PMC5749787
 
Books, Chapters, and Reviews
1. Cabrera SM, Henschel AM, Hessner MJ. Innate inflammation in type 1 diabetes. Transl Res. 2016 Jan;167(1):214-27. PMCID: PMC4626442
2. Kashmiri, HK, and SM Cabrera. 'Short Stature'. The 5 Minute Pediatric Consult Standard. Ed. Michael Cabana. 7th ed. New York: Wolters-Kluwer, 2015.
3. Cabrera SM, Rigby MR, Mirmira RG. Targeting regulatory T cells in the treatment of type 1 diabetes mellitus. Curr Mol Med. 2012 Dec;12(10):1261-72. PMCID: PMC3709459
4. Cabrera SM, Henschel AM, and Hessner MJ. Innate inflammation in type 1 diabetes. Trans Res. 2015 Apr 29. Epub ahead of print.
 

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