Medical College of Wisconsin
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Alexander V. Staruschenko PhD

Alexander V. Staruschenko PhD

Professor

Institution: Medical College of Wisconsin
Department: Physiology

Member of the Cardiovascular Center


Publications

  • Genetic mutation of Kcnj16 identifies Kir5.1-containing channels as key regulators of acute and chronic pH homeostasis. (Puissant MM, Muere C, Levchenko V, Manis AD, Martino P, Forster HV, Palygin O, Staruschenko A, Hodges MR) FASEB J 2019 Jan 03:fj201802257R PMID: 30605394 01/04/2019    
  • Visualization and Quantification of Mitochondrial Structure in the Endothelium of Intact Arteries. (Durand MJ, Ait-Aissa K, Levchenko V, Staruschenko A, Gutterman DD, Beyer AM) Cardiovasc Res 2018 Nov 22 PMID: 30476208 11/27/2018    
  • Characterization of purinergic receptor expression in ARPKD cystic epithelia. (Palygin O, Ilatovskaya DV, Levchenko V, Klemens CA, Dissanayake L, Williams AM, Pavlov TS, Staruschenko A) Purinergic Signal 2018 12;14(4):485-497 PMID: 30417216 PMCID: PMC6298916 11/13/2018    
  • Endothelin receptor A and p66Shc regulate spontaneous Ca oscillations in smooth muscle cells controlling renal arterial spontaneous motion. (Palygin O, Miller BS, Nishijima Y, Zhang DX, Staruschenko A, Sorokin A) FASEB J 2019 Feb;33(2):2636-2645 PMID: 30303741 PMCID: PMC6338658 10/12/2018    
  • Inactivation of p66Shc Decreases Afferent Arteriolar K Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats. (Miller BS, Blumenthal SR, Shalygin A, Wright KD, Staruschenko A, Imig JD, Sorokin A) Diabetes 2018 11;67(11):2206-2212 PMID: 30131395 PMCID: PMC6198347 08/23/2018       1 Citations
  • Role of the Scaffold Protein MIM in the Actin-Dependent Regulation of Epithelial Sodium Channels (ENaC). (Shuyskiy LS, Levchenko VV, Negulyaev YA, Staruschenko AV, Ilatovskaya DV) Acta Naturae 2018 Apr-Jun;10(2):97-103 PMID: 30116621 PMCID: PMC6087825 08/18/2018    
  • A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD. (Parnell SC, Magenheimer BS, Maser RL, Pavlov TS, Havens MA, Hastings ML, Jackson SF, Ward CJ, Peterson KR, Staruschenko A, Calvet JP) Hum Mol Genet 2018 10 01;27(19):3313-3324 PMID: 29931260 PMCID: PMC6140781 06/23/2018       1 Citations
  • Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections. (Bukowy JD, Dayton A, Cloutier D, Manis AD, Staruschenko A, Lombard JH, Solberg Woods LC, Beard DA, Cowley AW Jr) J Am Soc Nephrol 2018 Aug;29(8):2081-2088 PMID: 29921718 PMCID: PMC6065078 06/21/2018       1 Citations
  • Protective role of Trpc6 knockout in the progression of diabetic kidney disease. (Spires D, Ilatovskaya DV, Levchenko V, North PE, Geurts AM, Palygin O, Staruschenko A) Am J Physiol Renal Physiol 2018 Oct 01;315(4):F1091-F1097 PMID: 29923767 PMCID: PMC6230750 06/21/2018       3 Citations
  • Distal tubule basolateral potassium channels: cellular and molecular mechanisms of regulation. (Palygin O, Pochynyuk O, Staruschenko A) Curr Opin Nephrol Hypertens 2018 09;27(5):373-378 PMID: 29894319 PMCID: PMC6217967 06/13/2018    
  • βPix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells. (Ho PY, Li H, Pavlov TS, Tuerk RD, Tabares D, Brunisholz R, Neumann D, Staruschenko A, Hallows KR) J Biol Chem 2018 07 20;293(29):11612-11624 PMID: 29858246 PMCID: PMC6065188 06/03/2018       1 Citations
  • A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease. (Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW Jr, Birnbaumer L, Staruschenko A) J Am Soc Nephrol 2018 Jul;29(7):1917-1927 PMID: 29793963 PMCID: PMC6050934 05/26/2018    
  • Beneficial Effects of High Potassium: Contribution of Renal Basolateral K Channels. (Staruschenko A) Hypertension 2018 06;71(6):1015-1022 PMID: 29712740 PMCID: PMC5945313 05/02/2018    
  • Nitric oxide production by glomerular podocytes. (Palygin O, Ilatovskaya DV, Levchenko V, Endres BT, Geurts AM, Staruschenko A) Nitric Oxide 2018 01 30;72:24-31 PMID: 29128399 PMCID: PMC5776695 11/13/2017    
  • Role of adaptor protein p66Shc in renal pathologies. (Wright KD, Staruschenko A, Sorokin A) Am J Physiol Renal Physiol 2018 02 01;314(2):F143-F153 PMID: 28978535 PMCID: PMC5866456 10/06/2017       3 Citations
  • Essential role of Kir5.1 channels in renal salt handling and blood pressure control. (Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Pochynyuk OM, Jacob HJ, Geurts AM, Hodges MR, Staruschenko A) JCI Insight 2017 Sep 21;2(18) PMID: 28931751 PMCID: PMC5621918 09/22/2017       2 Citations
  • Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure. (Palygin O, Evans LC, Cowley AW Jr, Staruschenko A) J Am Heart Assoc 2017 Sep 12;6(9) PMID: 28899893 PMCID: PMC5634305 09/14/2017       4 Citations
  • Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats. (Pavlov TS, Levchenko V, Ilatovskaya DV, Li H, Palygin O, Pastor-Soler NM, Hallows KR, Staruschenko A) Front Physiol 2017;8:227 PMID: 28473772 PMCID: PMC5397526 05/06/2017    
  • Intravital imaging of the kidney in a rat model of salt-sensitive hypertension. (Endres BT, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Kamocka MM, McDermott-Roe C, Staruschenko A, Molitoris BA, Geurts AM, Palygin O) Am J Physiol Renal Physiol 2017 Aug 01;313(2):F163-F173 PMID: 28404591 PMCID: PMC5582897 04/14/2017       4 Citations
  • Hypertension and Diabetes Mellitus: The Chicken and Egg Problem. (Staruschenko A) Hypertension 2017 05;69(5):787-788 PMID: 28373592 PMCID: PMC5391301 04/05/2017       1 Citations
  • The normal increase in insulin after a meal may be required to prevent postprandial renal sodium and volume losses. (Irsik DL, Blazer-Yost BL, Staruschenko A, Brands MW) Am J Physiol Regul Integr Comp Physiol 2017 06 01;312(6):R965-R972 PMID: 28330966 PMCID: PMC5495919 03/24/2017       3 Citations
  • The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling. (Ilatovskaya DV, Palygin O, Levchenko V, Endres BT, Staruschenko A) Sci Rep 2017 03 22;7(1):299 PMID: 28331185 PMCID: PMC5428415 03/24/2017       12 Citations
  • Involvement of ENaC in the development of salt-sensitive hypertension. (Pavlov TS, Staruschenko A) Am J Physiol Renal Physiol 2017 Aug 01;313(2):F135-F140 PMID: 28003189 PMCID: PMC5582899 12/23/2016       10 Citations
  • High salt diet and caffeine: food for thought. (Staruschenko A, Ilatovskaya DV, Pavlov TS) J Thorac Dis 2016 Oct;8(10):E1410-E1412 PMID: 27867643 PMCID: PMC5107454 11/22/2016    
  • Protease-activated receptors in kidney disease progression. (Palygin O, Ilatovskaya DV, Staruschenko A) Am J Physiol Renal Physiol 2016 12 01;311(6):F1140-F1144 PMID: 27733370 PMCID: PMC5210204 10/14/2016       5 Citations
  • Functional and therapeutic importance of purinergic signaling in polycystic kidney disease. (Ilatovskaya DV, Palygin O, Staruschenko A) Am J Physiol Renal Physiol 2016 12 01;311(6):F1135-F1139 PMID: 27654892 PMCID: PMC5210209 09/23/2016       5 Citations
  • Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats. (Blass G, Levchenko V, Ilatovskaya DV, Staruschenko A) Physiol Rep 2016 09;4(17) PMID: 27597769 PMCID: PMC5027357 09/07/2016       2 Citations
  • Regulation of Polycystin-1 Function by Calmodulin Binding. (Doerr N, Wang Y, Kipp KR, Liu G, Benza JJ, Pletnev V, Pavlov TS, Staruschenko A, Mohieldin AM, Takahashi M, Nauli SM, Weimbs T) PLoS One 2016;11(8):e0161525 PMID: 27560828 PMCID: PMC4999191 08/26/2016       2 Citations
  • Renal sodium transport in renin-deficient Dahl salt-sensitive rats. (Pavlov TS, Levchenko V, Ilatovskaya DV, Moreno C, Staruschenko A) J Renin Angiotensin Aldosterone Syst 2016 Jul;17(3) PMID: 27443990 PMCID: PMC5100984 07/23/2016       6 Citations
  • The function of SH2B3 (LNK) in the kidney. (Blass G, Mattson DL, Staruschenko A) Am J Physiol Renal Physiol 2016 10 01;311(4):F682-F685 PMID: 27440780 PMCID: PMC5142233 07/22/2016       1 Citations
  • p66Shc regulates renal vascular tone in hypertension-induced nephropathy. (Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW Jr, Geurts AM, Staruschenko A, Imig JD, Sorokin A) J Clin Invest 2016 07 01;126(7):2533-46 PMID: 27270176 PMCID: PMC4922697 06/09/2016       6 Citations
  • Role and mechanisms of regulation of the basolateral K 4.1/K 5.1K channels in the distal tubules. (Palygin O, Pochynyuk O, Staruschenko A) Acta Physiol (Oxf) 2017 01;219(1):260-273 PMID: 27129733 PMCID: PMC5086442 05/01/2016       5 Citations
  • Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes. (Zappia KJ, Garrison SR, Palygin O, Weyer AD, Barabas ME, Lawlor MW, Staruschenko A, Stucky CL) PLoS One 2016;11(3):e0151602 PMID: 26978657 PMCID: PMC4792390 03/16/2016       10 Citations
  • Two-photon imaging of endothelin-1-mediated intracellular Ca(2+) handling in smooth muscle cells of rat renal resistance arteries. (Palygin O, Miller B, Ilatovskaya DV, Sorokin A, Staruschenko A) Life Sci 2016 Aug 15;159:140-143 PMID: 26682937 PMCID: PMC4902792 12/20/2015       1 Citations
  • Podocyte injury in diabetic nephropathy: implications of angiotensin II-dependent activation of TRPC channels. (Ilatovskaya DV, Levchenko V, Lowing A, Shuyskiy LS, Palygin O, Staruschenko A) Sci Rep 2015 Dec 10;5:17637 PMID: 26656101 PMCID: PMC4674698 12/15/2015       29 Citations
  • Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. (Cowley AW Jr, Yang C, Zheleznova NN, Staruschenko A, Kurth T, Rein L, Kumar V, Sadovnikov K, Dayton A, Hoffman M, Ryan RP, Skelton MM, Salehpour F, Ranji M, Geurts A) Hypertension 2016 Feb;67(2):440-50 PMID: 26644237 PMCID: PMC4713301 12/09/2015       26 Citations
  • Insulin and IGF-1 activate Kir4.1/5.1 channels in cortical collecting duct principal cells to control basolateral membrane voltage. (Zaika O, Palygin O, Tomilin V, Mamenko M, Staruschenko A, Pochynyuk O) Am J Physiol Renal Physiol 2016 Feb 15;310(4):F311-21 PMID: 26632606 PMCID: PMC4839479 12/04/2015       8 Citations
  • Use of Enzymatic Biosensors to Quantify Endogenous ATP or H2O2 in the Kidney. (Palygin O, Levchenko V, Evans LC, Blass G, Cowley AW Jr, Staruschenko A) J Vis Exp 2015 Oct 12(104) PMID: 26485400 PMCID: PMC4684070 10/21/2015       5 Citations
  • S&R Foundation 15th Anniversary. (Staruschenko A, Weber CR, Pochynyuk O, McCole DF) Physiologist 2015 Sep;58(5):241-2 PMID: 26442383 10/08/2015    
  • Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium. (Pavlov TS, Ilatovskaya DV, Palygin O, Levchenko V, Pochynyuk O, Staruschenko A) J Vis Exp 2015 Sep 01(103) PMID: 26381526 PMCID: PMC4581700 09/19/2015       5 Citations
  • Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli. (Ilatovskaya DV, Palygin O, Levchenko V, Staruschenko A) J Vis Exp 2015 Jun 27(100):e52850 PMID: 26167808 PMCID: PMC4544950 07/15/2015       8 Citations
  • Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta. (Endres BT, Staruschenko A, Schulte M, Geurts AM, Palygin O) J Vis Exp 2015 Jun 10(100):e52734 PMID: 26132549 PMCID: PMC4545029 07/02/2015       1 Citations
  • TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases. (Ilatovskaya DV, Staruschenko A) Am J Physiol Renal Physiol 2015 Sep 01;309(5):F393-7 PMID: 26084930 PMCID: PMC4556891 06/19/2015       23 Citations
  • Inhibition of ENaC by endothelin-1. (Sorokin A, Staruschenko A) Vitam Horm 2015;98:155-87 PMID: 25817869 PMCID: PMC4950931 03/31/2015       4 Citations
  • Acetylation stimulates the epithelial sodium channel by reducing its ubiquitination and degradation. (Butler PL, Staruschenko A, Snyder PM) J Biol Chem 2015 May 15;290(20):12497-503 PMID: 25787079 PMCID: PMC4432271 03/20/2015       9 Citations
  • Cross-talk between insulin and IGF-1 receptors in the cortical collecting duct principal cells: implication for ENaC-mediated Na+ reabsorption. (Ilatovskaya DV, Levchenko V, Brands MW, Pavlov TS, Staruschenko A) Am J Physiol Renal Physiol 2015 Apr 01;308(7):F713-9 PMID: 25651558 PMCID: PMC4385890 02/05/2015       10 Citations
  • Impaired epithelial Na+ channel activity contributes to cystogenesis and development of autosomal recessive polycystic kidney disease in PCK rats. (Pavlov TS, Levchenko V, Ilatovskaya DV, Palygin O, Staruschenko A) Pediatr Res 2015 Jan;77(1-1):64-9 PMID: 25279988 PMCID: PMC4268054 10/04/2014       8 Citations
  • Role of Rho GDP dissociation inhibitor α in control of epithelial sodium channel (ENaC)-mediated sodium reabsorption. (Pavlov TS, Levchenko V, Staruschenko A) J Biol Chem 2014 Oct 10;289(41):28651-9 PMID: 25164814 PMCID: PMC4192514 08/29/2014       4 Citations
  • Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. (Endres BT, Priestley JR, Palygin O, Flister MJ, Hoffman MJ, Weinberg BD, Grzybowski M, Lombard JH, Staruschenko A, Moreno C, Jacob HJ, Geurts AM) Proc Natl Acad Sci U S A 2014 Sep 02;111(35):12817-22 PMID: 25136115 PMCID: PMC4156702 08/20/2014       24 Citations
  • To cleave or not to cleave: role of ADAM17 in cell proliferation in PKD. (Staruschenko A) Am J Physiol Renal Physiol 2014 Sep 15;307(6):F658-9 PMID: 25056345 PMCID: PMC4166730 07/25/2014    
  • Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition. (Hye Khan MA, Pavlov TS, Christain SV, Neckář J, Staruschenko A, Gauthier KM, Capdevila JH, Falck JR, Campbell WB, Imig JD) Clin Sci (Lond) 2014 Oct;127(7):463-74 PMID: 24707975 PMCID: PMC4167712 04/09/2014       33 Citations
  • Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli. (Ilatovskaya DV, Palygin O, Chubinskiy-Nadezhdin V, Negulyaev YA, Ma R, Birnbaumer L, Staruschenko A) Kidney Int 2014 Sep;86(3):506-14 PMID: 24646854 PMCID: PMC4149864 03/22/2014       38 Citations
  • PC and PKC: in vivo vs. in vitro. (Staruschenko A, Safonova TA) Am J Physiol Renal Physiol 2014 Mar 01;306(5):F507-8 PMID: 24370588 PMCID: PMC3949034 12/29/2013    
  • Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. (Ilatovskaya DV, Palygin O, Levchenko V, Staruschenko A) Am J Physiol Cell Physiol 2013 Nov 15;305(10):C1050-9 PMID: 24048730 PMCID: PMC3840197 09/21/2013       20 Citations
  • Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells. (Ilatovskaya DV, Chubinskiy-Nadezhdin V, Pavlov TS, Shuyskiy LS, Tomilin V, Palygin O, Staruschenko A, Negulyaev YA) Cell Tissue Res 2013 Dec;354(3):783-92 PMID: 24036843 PMCID: PMC3850072 09/17/2013       5 Citations
  • Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine. (Zaika OL, Mamenko M, Palygin O, Boukelmoune N, Staruschenko A, Pochynyuk O) Am J Physiol Renal Physiol 2013 Nov 01;305(9):F1277-87 PMID: 23986512 PMCID: PMC3840222 08/30/2013       22 Citations
  • Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat. (Hye Khan MA, Neckár J, Manthati V, Errabelli R, Pavlov TS, Staruschenko A, Falck JR, Imig JD) Hypertension 2013 Nov;62(5):905-13 PMID: 23980070 PMCID: PMC3872985 08/28/2013       33 Citations
  • Aldosterone-dependent trans-activation and epigenetic derepression of ENaC: where is the balance? (Staruschenko A) Am J Physiol Renal Physiol 2013 Oct 01;305(7):F968-9 PMID: 23842778 PMCID: PMC3798737 07/12/2013       1 Citations
  • Epidermal growth factors in the kidney and relationship to hypertension. (Staruschenko A, Palygin O, Ilatovskaya DV, Pavlov TS) Am J Physiol Renal Physiol 2013 Jul 01;305(1):F12-20 PMID: 23637204 PMCID: PMC3725676 05/03/2013       17 Citations
  • Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. (Pavlov TS, Levchenko V, O'Connor PM, Ilatovskaya DV, Palygin O, Mori T, Mattson DL, Sorokin A, Lombard JH, Cowley AW Jr, Staruschenko A) J Am Soc Nephrol 2013 Jun;24(7):1053-62 PMID: 23599382 PMCID: PMC3699826 04/20/2013       35 Citations
  • Real-time electrochemical detection of ATP and H₂O₂ release in freshly isolated kidneys. (Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Ryan RP, Cowley AW Jr, Staruschenko A) Am J Physiol Renal Physiol 2013 Jul 01;305(1):F134-41 PMID: 23594827 PMCID: PMC3725679 04/19/2013       18 Citations
  • Detection of endogenous substances with enzymatic microelectrode biosensors in the kidney. (Palygin O, Staruschenko A) Am J Physiol Regul Integr Comp Physiol 2013 Jul 15;305(2):R89-91 PMID: 23594609 PMCID: PMC3726996 04/19/2013       2 Citations
  • Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct. (Pavlov TS, Ilatovskaya DV, Levchenko V, Li L, Ecelbarger CM, Staruschenko A) FASEB J 2013 Jul;27(7):2723-32 PMID: 23558339 PMCID: PMC3688749 04/06/2013       23 Citations
  • Single-channel analysis of TRPC channels in the podocytes of freshly isolated Glomeruli. (Ilatovskaya DV, Staruschenko A) Methods Mol Biol 2013;998:355-69 PMID: 23529444 PMCID: PMC4181531 03/27/2013       13 Citations
  • Recording ion channels in isolated, split-opened tubules. (Mironova E, Bugay V, Pochynyuk O, Staruschenko A, Stockand JD) Methods Mol Biol 2013;998:341-53 PMID: 23529443 PMCID: PMC4181527 03/27/2013       5 Citations
  • 2013 Renal Section Young Investigator Award: Alexander Staruschenko. (Stockand JD) Am J Physiol Renal Physiol 2013 Mar 13: PMID: 23486010 03/15/2013    
  • G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. (Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F) Proc Natl Acad Sci U S A 2012 Dec 26;109(52):21462-7 PMID: 23236168 PMCID: PMC3535663 12/14/2012       19 Citations
  • Regulation of transport in the connecting tubule and cortical collecting duct. (Staruschenko A) Compr Physiol 2012 Apr;2(2):1541-84 PMID: 23227301 PMCID: PMC3516049 12/12/2012       55 Citations
  • Direct activation of ENaC by angiotensin II: recent advances and new insights. (Zaika O, Mamenko M, Staruschenko A, Pochynyuk O) Curr Hypertens Rep 2013 Feb;15(1):17-24 PMID: 23180052 PMCID: PMC3545060 11/28/2012       20 Citations
  • ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1. (Ilatovskaya DV, Pavlov TS, Levchenko V, Staruschenko A) Am J Physiol Cell Physiol 2013 Jan 01;304(1):C102-11 PMID: 23135700 PMCID: PMC3543576 11/09/2012       30 Citations
  • Regulation of TRPC6 Channels by Non-Steroidal Anti-Inflammatory Drugs. (Ilatovskaya DV, Pavlov TS, Negulyaev YA, Staruschenko A) Biochem (Mosc) Suppl Ser A Membr Cell Biol 2012 Jul;6(3):265-272 PMID: 25279100 PMCID: PMC4180105 07/01/2012    
  • Role of βPix in the Kidney. (Staruschenko A, Sorokin A) Front Physiol 2012;3:154 PMID: 22654768 PMCID: PMC3361069 06/02/2012    
  • [Mechanism of epithelial sodium channel (ENaC) regulation by cortactin: involvement of dynamin]. (Ilatovskaia DV, Pavlov TS, Neguliaev IuA, Starushchenko AV) Tsitologiia 2011;53(11):903-10 PMID: 22332421 02/16/2012       3 Citations
  • Angiotensin II increases activity of the epithelial Na+ channel (ENaC) in distal nephron additively to aldosterone. (Mamenko M, Zaika O, Ilatovskaya DV, Staruschenko A, Pochynyuk O) J Biol Chem 2012 Jan 02;287(1):660-71 PMID: 22086923 PMCID: PMC3249120 11/17/2011       81 Citations
  • Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC). (Pavlov TS, Ilatovskaya DV, Levchenko V, Mattson DL, Roman RJ, Staruschenko A) Am J Physiol Renal Physiol 2011 Sep;301(3):F672-81 PMID: 21697242 PMCID: PMC3174560 06/24/2011       39 Citations
  • Cortical actin binding protein cortactin mediates ENaC activity via Arp2/3 complex. (Ilatovskaya DV, Pavlov TS, Levchenko V, Negulyaev YA, Staruschenko A) FASEB J 2011 Aug;25(8):2688-99 PMID: 21536685 05/04/2011       28 Citations
  • NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli. (Ilatovskaya DV, Levchenko V, Ryan RP, Cowley AW Jr, Staruschenko A) Biochem Biophys Res Commun 2011 May 06;408(2):242-7 PMID: 21473850 PMCID: PMC3093766 04/09/2011       17 Citations
  • Novel role of Rac1/WAVE signaling mechanism in regulation of the epithelial Na+ channel. (Karpushev AV, Levchenko V, Ilatovskaya DV, Pavlov TS, Staruschenko A) Hypertension 2011 May;57(5):996-1002 PMID: 21464391 04/06/2011       25 Citations
  • Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells. (Zheleznova NN, Wilson PD, Staruschenko A) Biochim Biophys Acta 2011 Oct;1812(10):1301-13 PMID: 20959142 PMCID: PMC3038174 10/21/2010       39 Citations
  • The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC. (Karpushev AV, Ilatovskaya DV, Staruschenko A) BMC Res Notes 2010 Jul 27;3:210 PMID: 20663206 PMCID: PMC2918634 07/29/2010    
  • Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors. (Pavlov TS, Imig JD, Staruschenko A) PPAR Res 2010;2010:703735 PMID: 20613963 PMCID: PMC2896859 07/09/2010    
  • Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2. (Pavlov TS, Chahdi A, Ilatovskaya DV, Levchenko V, Vandewalle A, Pochynyuk O, Sorokin A, Staruschenko A) J Am Soc Nephrol 2010 May;21(5):833-43 PMID: 20338996 PMCID: PMC2865733 03/27/2010       52 Citations
  • Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel. (Staruschenko A, Jeske NA, Akopian AN) J Biol Chem 2010 May 14;285(20):15167-77 PMID: 20231274 PMCID: PMC2865321 03/17/2010       110 Citations
  • Intact cytoskeleton is required for small G protein dependent activation of the epithelial Na+ channel. (Karpushev AV, Ilatovskaya DV, Pavlov TS, Negulyaev YA, Staruschenko A) PLoS One 2010 Jan 21;5(1):e8827 PMID: 20098689 PMCID: PMC2809106 01/26/2010       34 Citations
  • EGF and its related growth factors mediate sodium transport in mpkCCDc14 cells via ErbB2 (neu/HER-2) receptor. (Levchenko V, Zheleznova NN, Pavlov TS, Vandewalle A, Wilson PD, Staruschenko A) J Cell Physiol 2010 Apr;223(1):252-9 PMID: 20049896 01/06/2010       20 Citations
  • Peroxisome proliferator-activated receptor gamma antagonists decrease Na+ transport via the epithelial Na+ channel. (Pavlov TS, Levchenko V, Karpushev AV, Vandewalle A, Staruschenko A) Mol Pharmacol 2009 Dec;76(6):1333-40 PMID: 19752200 09/16/2009       17 Citations
  • Muscarinic M1 modulation of acid-sensing ion channels. (Dorofeeva NA, Karpushev AV, Nikolaev MV, Bolshakov KV, Stockand JD, Staruschenko A) Neuroreport 2009 Oct 07;20(15):1386-91 PMID: 19730136 09/05/2009       4 Citations
  • Intrinsic voltage dependence of the epithelial Na+ channel is masked by a conserved transmembrane domain tryptophan. (Pochynyuk O, Kucher V, Boiko N, Mironova E, Staruschenko A, Karpushev AV, Tong Q, Hendron E, Stockand J) J Biol Chem 2009 Sep 18;284(38):25512-21 PMID: 19620245 PMCID: PMC2757952 07/22/2009       7 Citations
  • Regulation of ENaC expression at the cell surface by Rab11. (Karpushev AV, Levchenko V, Pavlov TS, Lam V, Vinnakota KC, Vandewalle A, Wakatsuki T, Staruschenko A) Biochem Biophys Res Commun 2008 Dec 12;377(2):521-525 PMID: 18926797 PMCID: PMC2612579 10/18/2008       34 Citations
  • Insight toward epithelial Na+ channel mechanism revealed by the acid-sensing ion channel 1 structure. (Stockand JD, Staruschenko A, Pochynyuk O, Booth RE, Silverthorn DU) IUBMB Life 2008 Sep;60(9):620-8 PMID: 18459164 05/07/2008       76 Citations
  • Mechanisms of non-steroid anti-inflammatory drugs action on ASICs expressed in hippocampal interneurons. (Dorofeeva NA, Barygin OI, Staruschenko A, Bolshakov KV, Magazanik LG) J Neurochem 2008 Jul;106(1):429-41 PMID: 18410516 04/16/2008       45 Citations
  • Ion channel regulation by Ras, Rho, and Rab small GTPases. (Pochynyuk O, Stockand JD, Staruschenko A) Exp Biol Med (Maywood) 2007 Nov;232(10):1258-65 PMID: 17959838 10/26/2007       34 Citations
  • Molecular determinants of PI(4,5)P2 and PI(3,4,5)P3 regulation of the epithelial Na+ channel. (Pochynyuk O, Tong Q, Medina J, Vandewalle A, Staruschenko A, Bugaj V, Stockand JD) J Gen Physiol 2007 Oct;130(4):399-413 PMID: 17893193 PMCID: PMC2151653 09/26/2007       47 Citations
  • Subunit-dependent cadmium and nickel inhibition of acid-sensing ion channels. (Staruschenko A, Dorofeeva NA, Bolshakov KV, Stockand JD) Dev Neurobiol 2007 Jan;67(1):97-107 PMID: 17443775 04/20/2007       42 Citations
  • Acute regulation of the epithelial Na+ channel by phosphatidylinositide 3-OH kinase signaling in native collecting duct principal cells. (Staruschenko A, Pochynyuk O, Vandewalle A, Bugaj V, Stockand JD) J Am Soc Nephrol 2007 Jun;18(6):1652-61 PMID: 17442787 04/20/2007       67 Citations
  • Quantifying RhoA facilitated trafficking of the epithelial Na+ channel toward the plasma membrane with total internal reflection fluorescence-fluorescence recovery after photobleaching. (Pochynyuk O, Staruschenko A, Bugaj V, Lagrange L, Stockand JD) J Biol Chem 2007 May 11;282(19):14576-85 PMID: 17376773 03/23/2007       33 Citations
  • Binding and direct activation of the epithelial Na+ channel (ENaC) by phosphatidylinositides. (Pochynyuk O, Tong Q, Staruschenko A, Stockand JD) J Physiol 2007 Apr 15;580(Pt. 2):365-72 PMID: 17272344 PMCID: PMC2075560 02/03/2007       38 Citations
  • Functional reconstitution of the human epithelial Na+ channel in a mammalian expression system. (Staruschenko A, Booth RE, Pochynyuk O, Stockand JD, Tong Q) Methods Mol Biol 2006;337:3-13 PMID: 16929934 08/26/2006       14 Citations
  • Magnesium permeation through mechanosensitive channels: single-current measurements. (Staruschenko AV, Sudarikova AV, Negulyaev YA, Morachevskaya EA) Cell Res 2006 Aug;16(8):723-30 PMID: 16871269 07/28/2006       8 Citations
  • Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling. (Pochynyuk O, Medina J, Gamper N, Genth H, Stockand JD, Staruschenko A) J Biol Chem 2006 Sep 08;281(36):26520-7 PMID: 16829523 07/11/2006       54 Citations
  • Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides. (Pochynyuk O, Tong Q, Staruschenko A, Ma HP, Stockand JD) Am J Physiol Renal Physiol 2006 May;290(5):F949-57 PMID: 16601296 04/08/2006       51 Citations
  • Regulation of epithelial Na+ channel activity by conserved serine/threonine switches within sorting signals. (Staruschenko A, Pochynyuk O, Stockand JD) J Biol Chem 2005 Nov 25;280(47):39161-7 PMID: 16203727 10/06/2005       27 Citations
  • Identification of a functional phosphatidylinositol 3,4,5-trisphosphate binding site in the epithelial Na+ channel. (Pochynyuk O, Staruschenko A, Tong Q, Medina J, Stockand JD) J Biol Chem 2005 Nov 11;280(45):37565-71 PMID: 16154997 09/13/2005       55 Citations
  • Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel. (Staruschenko A, Pochynyuk OM, Tong Q, Stockand JD) Biochim Biophys Acta 2005 May 20;1669(2):108-15 PMID: 15893513 05/17/2005       26 Citations
  • Actin cytoskeleton disassembly affects conductive properties of stretch-activated cation channels in leukaemia cells. (Staruschenko A, Negulyaev YA, Morachevskaya EA) Biochim Biophys Acta 2005 May 15;1669(1):53-60 PMID: 15842999 04/22/2005       22 Citations
  • Epithelial Na+ channel subunit stoichiometry. (Staruschenko A, Adams E, Booth RE, Stockand JD) Biophys J 2005 Jun;88(6):3966-75 PMID: 15821171 PMCID: PMC1305628 04/12/2005       75 Citations
  • Rho small GTPases activate the epithelial Na(+) channel. (Staruschenko A, Nichols A, Medina JL, Camacho P, Zheleznova NN, Stockand JD) J Biol Chem 2004 Nov 26;279(48):49989-94 PMID: 15448132 09/28/2004       55 Citations
  • Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling. (Staruschenko A, Patel P, Tong Q, Medina JL, Stockand JD) J Biol Chem 2004 Sep 03;279(36):37771-8 PMID: 15215250 06/25/2004       72 Citations
  • Fluorescence resonance energy transfer analysis of subunit stoichiometry of the epithelial Na+ channel. (Staruschenko A, Medina JL, Patel P, Shapiro MS, Booth RE, Stockand JD) J Biol Chem 2004 Jun 25;279(26):27729-34 PMID: 15096495 04/21/2004       56 Citations
  • [Inhibiting and stimulating effect of amiloride on potential-dependent cation channels in K562 cells]. (Starushchenko AV, Neguliaev IuA, Morachevskaia EZ) Tsitologiia 2002;44(7):676-80 PMID: 12455378 11/29/2002    
  • Mechanosensitive cation channels in human leukaemia cells: calcium permeation and blocking effect. (Staruschenko AV, Vedernikova EA) J Physiol 2002 May 15;541(Pt 1):81-90 PMID: 12015421 PMCID: PMC2290313 05/17/2002       15 Citations
  • Giant multimodal heart motoneurons of Achatina fulica: a new cardioregulatory input in pulmonates. (Zhuravlev V, Bugaj V, Kodirov S, Safonova T, Staruschenko A) Comp Biochem Physiol A Mol Integr Physiol 2001 Aug;130(1):183-96 PMID: 11672694 10/24/2001       14 Citations
  • [Activation of mechanosensitive ion channels in plasma membrane of K562 cells]. (Starushchenko AV, Mamin AG, Neguliaev IuA, Vedernikova EA) Tsitologiia 2000;42(7):669-74 PMID: 10994084 09/20/2000       1 Citations
  • Last update: 02/21/2019
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