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Alfredo Dubra PhD

Alfredo Dubra PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Ophthalmology
Program: Research

Member of the Neuroscience Research Center


Publications

  • Adaptive optics imaging of healthy and abnormal regions of retinal nerve fiber bundles of patients with glaucoma. (Chen MF, Chui TY, Alhadeff P, Rosen RB, Ritch R, Dubra A, Hood DC) Invest Ophthalmol Vis Sci 2015 Jan;56(1):674-81 PMID: 25574048 PMCID: PMC4311778 01/13/2015
  • Assessing photoreceptor structure after macular hole closure. (Hansen S, Batson S, Weinlander KM, Cooper RF, Scoles DH, Karth PA, Weinberg DV, Dubra A, Kim JE, Carroll J, Wirostko WJ) Retin Cases Brief Rep 2015;9(1):15-20 PMID: 25525907 PMCID: PMC4554764 12/20/2014
  • Assessment of perfused foveal microvascular density and identification of nonperfused capillaries in healthy and vasculopathic eyes. (Pinhas A, Razeen M, Dubow M, Gan A, Chui TY, Shah N, Mehta M, Gentile RC, Weitz R, Walsh JB, Sulai YN, Carroll J, Dubra A, Rosen RB) Invest Ophthalmol Vis Sci 2014 Dec;55(12):8056-66 PMID: 25414179 PMCID: PMC4266074 11/22/2014
  • Non-common path aberration correction in an adaptive optics scanning ophthalmoscope. (Sulai YN, Dubra A) Biomed Opt Express 2014 Sep 1;5(9):3059-73 PMID: 25401020 PMCID: PMC4230870 11/18/2014
  • Genotype-dependent variability in residual cone structure in achromatopsia: toward developing metrics for assessing cone health. (Dubis AM, Cooper RF, Aboshiha J, Langlo CS, Sundaram V, Liu B, Collison F, Fishman GA, Moore AT, Webster AR, Dubra A, Carroll J, Michaelides M) Invest Ophthalmol Vis Sci 2014 Nov;55(11):7303-11 PMID: 25277229 PMCID: PMC4235328 10/04/2014
  • Author response: relationship between foveal cone specialization and pit morphology in albinism. (Wilk MA, Dubra A, Curcio CA, Brilliant MH, Summers CG, Carroll J) Invest Ophthalmol Vis Sci 2014 Sep;55(9):5923 PMID: 25237180 09/23/2014
  • A prospective longitudinal study of retinal structure and function in achromatopsia. (Aboshiha J, Dubis AM, Cowing J, Fahy RT, Sundaram V, Bainbridge JW, Ali RR, Dubra A, Nardini M, Webster AR, Moore AT, Rubin G, Carroll J, Michaelides M) Invest Ophthalmol Vis Sci 2014 Sep;55(9):5733-43 PMID: 25103266 PMCID: PMC4161486 08/12/2014
  • In vivo imaging of human cone photoreceptor inner segments. (Scoles D, Sulai YN, Langlo CS, Fishman GA, Curcio CA, Carroll J, Dubra A) Invest Ophthalmol Vis Sci 2014 Jul;55(7):4244-51 PMID: 24906859 PMCID: PMC4095721 06/08/2014
  • Microscopic inner retinal hyper-reflective phenotypes in retinal and neurologic disease. (Scoles D, Higgins BP, Cooper RF, Dubis AM, Summerfelt P, Weinberg DV, Kim JE, Stepien KE, Carroll J, Dubra A) Invest Ophthalmol Vis Sci 2014 Jul;55(7):4015-29 PMID: 24894394 PMCID: PMC4078949 06/05/2014
  • The reliability of parafoveal cone density measurements. (Liu BS, Tarima S, Visotcky A, Pechauer A, Cooper RF, Landsem L, Wilk MA, Godara P, Makhijani V, Sulai YN, Syed N, Yasumura G, Garg AK, Pennesi ME, Lujan BJ, Dubra A, Duncan JL, Carroll J) Br J Ophthalmol 2014 Aug;98(8):1126-31 PMID: 24855115 PMCID: PMC4112420 05/24/2014
  • Relationship between foveal cone specialization and pit morphology in albinism. (Wilk MA, McAllister JT, Cooper RF, Dubis AM, Patitucci TN, Summerfelt P, Anderson JL, Stepien KE, Costakos DM, Connor TB Jr, Wirostko WJ, Chiang PW, Dubra A, Curcio CA, Brilliant MH, Summers CG, Carroll J) Invest Ophthalmol Vis Sci 2014 Jul;55(7):4186-98 PMID: 24845642 PMCID: PMC4098060 05/23/2014
  • Comparison of adaptive optics scanning light ophthalmoscopic fluorescein angiography and offset pinhole imaging. (Chui TY, Dubow M, Pinhas A, Shah N, Gan A, Weitz R, Sulai YN, Dubra A, Rosen RB) Biomed Opt Express 2014 Apr 1;5(4):1173-89 PMID: 24761299 PMCID: PMC3985984 04/25/2014
  • Outer retinal structure after closed-globe blunt ocular trauma. (Flatter JA, Cooper RF, Dubow MJ, Pinhas A, Singh RS, Kapur R, Shah N, Walsh RD, Hong SH, Weinberg DV, Stepien KE, Wirostko WJ, Robison S, Dubra A, Rosen RB, Connor TB Jr, Carroll J) Retina 2014 Oct;34(10):2133-46 PMID: 24752010 PMCID: PMC4175068 04/23/2014
  • Visualization of retinal vascular structure and perfusion with a nonconfocal adaptive optics scanning light ophthalmoscope. (Sulai YN, Scoles D, Harvey Z, Dubra A) J Opt Soc Am A Opt Image Sci Vis 2014 Mar 1;31(3):569-79 PMID: 24690655 PMCID: PMC4465430 04/03/2014
  • Classification of human retinal microaneurysms using adaptive optics scanning light ophthalmoscope fluorescein angiography. (Dubow M, Pinhas A, Shah N, Cooper RF, Gan A, Gentile RC, Hendrix V, Sulai YN, Carroll J, Chui TY, Walsh JB, Weitz R, Dubra A, Rosen RB) Invest Ophthalmol Vis Sci 2014 Mar;55(3):1299-309 PMID: 24425852 PMCID: PMC3943418 01/16/2014
  • In vivo imaging of retinal pigment epithelium cells in age related macular degeneration. (Rossi EA, Rangel-Fonseca P, Parkins K, Fischer W, Latchney LR, Folwell MA, Williams DR, Dubra A, Chung MM) Biomed Opt Express 2013;4(11):2527-39 PMID: 24298413 PMCID: PMC3829547 12/04/2013
  • Retinal structure and function in achromatopsia: implications for gene therapy. (Sundaram V, Wilde C, Aboshiha J, Cowing J, Han C, Langlo CS, Chana R, Davidson AE, Sergouniotis PI, Bainbridge JW, Ali RR, Dubra A, Rubin G, Webster AR, Moore AT, Nardini M, Carroll J, Michaelides M) Ophthalmology 2014 Jan;121(1):234-45 PMID: 24148654 PMCID: PMC3895408 10/24/2013
  • Human cone visual pigment deletions spare sufficient photoreceptors to warrant gene therapy. (Cideciyan AV, Hufnagel RB, Carroll J, Sumaroka A, Luo X, Schwartz SB, Dubra A, Land M, Michaelides M, Gardner JC, Hardcastle AJ, Moore AT, Sisk RA, Ahmed ZM, Kohl S, Wissinger B, Jacobson SG) Hum Gene Ther 2013 Dec;24(12):993-1006 PMID: 24067079 PMCID: PMC3868405 09/27/2013
  • In vivo dark-field imaging of the retinal pigment epithelium cell mosaic. (Scoles D, Sulai YN, Dubra A) Biomed Opt Express 2013;4(9):1710-23 PMID: 24049692 PMCID: PMC3771842 09/21/2013
  • In vivo imaging of human retinal microvasculature using adaptive optics scanning light ophthalmoscope fluorescein angiography. (Pinhas A, Dubow M, Shah N, Chui TY, Scoles D, Sulai YN, Weitz R, Walsh JB, Carroll J, Dubra A, Rosen RB) Biomed Opt Express 2013;4(8):1305-17 PMID: 24009994 PMCID: PMC3756583 09/07/2013
  • A lensing effect of inner retinal cysts on images of the photoreceptor mosaic. (Langlo CS, Flatter JA, Dubra A, Wirostko WJ, Carroll J) Retina 2014 Feb;34(2):421-2 PMID: 23974999 PMCID: PMC3946899 08/27/2013
  • Outer retinal structure in best vitelliform macular dystrophy. (Kay DB, Land ME, Cooper RF, Dubis AM, Godara P, Dubra A, Carroll J, Stepien KE) JAMA Ophthalmol 2013 Sep;131(9):1207-15 PMID: 23765342 PMCID: PMC3968428 06/15/2013
  • Automatic cone photoreceptor segmentation using graph theory and dynamic programming. (Chiu SJ, Lokhnygina Y, Dubis AM, Dubra A, Carroll J, Izatt JA, Farsiu S) Biomed Opt Express 2013 Jun 1;4(6):924-37 PMID: 23761854 PMCID: PMC3675871 06/14/2013
  • Automatic detection of modal spacing (Yellott's ring) in adaptive optics scanning light ophthalmoscope images. (Cooper RF, Langlo CS, Dubra A, Carroll J) Ophthalmic Physiol Opt 2013 Jul;33(4):540-9 PMID: 23668233 PMCID: PMC3690144 05/15/2013
  • Adaptive optics retinal imaging--clinical opportunities and challenges. (Carroll J, Kay DB, Scoles D, Dubra A, Lombardo M) Curr Eye Res 2013 Jul;38(7):709-21 PMID: 23621343 PMCID: PMC4031042 04/30/2013
  • Selective cone photoreceptor injury in acute macular neuroretinopathy. (Hansen SO, Cooper RF, Dubra A, Carroll J, Weinberg DV) Retina 2013 Sep;33(8):1650-8 PMID: 23615345 PMCID: PMC4065781 04/26/2013
  • First-order design of a reflective viewfinder for adaptive optics ophthalmoscopy. (Dubra A, Sulai YN) Opt Express 2012 Nov 19;20(24):26596-605 PMID: 23187514 PMCID: PMC3601596 11/29/2012
  • The effect of cone opsin mutations on retinal structure and the integrity of the photoreceptor mosaic. (Carroll J, Dubra A, Gardner JC, Mizrahi-Meissonnier L, Cooper RF, Dubis AM, Nordgren R, Genead M, Connor TB Jr, Stepien KE, Sharon D, Hunt DM, Banin E, Hardcastle AJ, Moore AT, Williams DR, Fishman G, Neitz J, Neitz M, Michaelides M) Invest Ophthalmol Vis Sci 2012 Dec;53(13):8006-15 PMID: 23139274 PMCID: PMC3816954 11/10/2012
  • Assessing retinal structure in complete congenital stationary night blindness and Oguchi disease. (Godara P, Cooper RF, Sergouniotis PI, Diederichs MA, Streb MR, Genead MA, McAnany JJ, Webster AR, Moore AT, Dubis AM, Neitz M, Dubra A, Stone EM, Fishman GA, Han DP, Michaelides M, Carroll J) Am J Ophthalmol 2012 Dec;154(6):987-1001.e1 PMID: 22959359 PMCID: PMC3498541 09/11/2012
  • Adaptive optics scanning ophthalmoscopy with annular pupils. (Sulai YN, Dubra A) Biomed Opt Express 2012 Jul 1;3(7):1647-61 PMID: 22808435 PMCID: PMC3395488 07/19/2012
  • Adaptive optics retinal imaging in the living mouse eye. (Geng Y, Dubra A, Yin L, Merigan WH, Sharma R, Libby RT, Williams DR) Biomed Opt Express 2012 Apr 1;3(4):715-34 PMID: 22574260 PMCID: PMC3345801 05/11/2012
  • Repeatability of in vivo parafoveal cone density and spacing measurements. (Garrioch R, Langlo C, Dubis AM, Cooper RF, Dubra A, Carroll J) Optom Vis Sci 2012 May;89(5):632-43 PMID: 22504330 PMCID: PMC3348369 04/17/2012
  • Subclinical photoreceptor disruption in response to severe head trauma. (Stepien KE, Martinez WM, Dubis AM, Cooper RF, Dubra A, Carroll J) Arch Ophthalmol 2012 Mar;130(3):400-2 PMID: 22411676 PMCID: PMC3329123 03/14/2012
  • Relationship between the foveal avascular zone and foveal pit morphology. (Dubis AM, Hansen BR, Cooper RF, Beringer J, Dubra A, Carroll J) Invest Ophthalmol Vis Sci 2012 Mar;53(3):1628-36 PMID: 22323466 PMCID: PMC3339921 02/11/2012
  • Spatial and temporal variation of rod photoreceptor reflectance in the human retina. (Cooper RF, Dubis AM, Pavaskar A, Rha J, Dubra A, Carroll J) Biomed Opt Express 2011 Sep 1;2(9):2577-89 PMID: 21991550 PMCID: PMC3184867 10/13/2011
  • Retinal crystals in type 2 idiopathic macular telangiectasia. (Sallo FB, Leung I, Chung M, Wolf-Schnurrbusch UE, Dubra A, Williams DR, Clemons T, Pauleikhoff D, Bird AC, Peto T, MacTel Study Group) Ophthalmology 2011 Dec;118(12):2461-7 PMID: 21839520 PMCID: PMC3433242 08/16/2011
  • Photoreceptor structure and function in patients with congenital achromatopsia. (Genead MA, Fishman GA, Rha J, Dubis AM, Bonci DM, Dubra A, Stone EM, Neitz M, Carroll J) Invest Ophthalmol Vis Sci 2011 Sep;52(10):7298-308 PMID: 21778272 PMCID: PMC3183969 07/23/2011
  • Noninvasive imaging of the human rod photoreceptor mosaic using a confocal adaptive optics scanning ophthalmoscope. (Dubra A, Sulai Y, Norris JL, Cooper RF, Dubis AM, Williams DR, Carroll J) Biomed Opt Express 2011 Jul 1;2(7):1864-76 PMID: 21750765 PMCID: PMC3130574 07/14/2011
  • Reflective afocal broadband adaptive optics scanning ophthalmoscope. (Dubra A, Sulai Y) Biomed Opt Express 2011 Jun 1;2(6):1757-68 PMID: 21698035 PMCID: PMC3114240 06/24/2011
  • Variability in parafoveal cone mosaic in normal trichromatic individuals. (Dees EW, Dubra A, Baraas RC) Biomed Opt Express 2011;2(5):1351-8 PMID: 21559146 PMCID: PMC3087591 05/12/2011
  • Optical properties of the mouse eye. (Geng Y, Schery LA, Sharma R, Dubra A, Ahmad K, Libby RT, Williams DR) Biomed Opt Express 2011;2(4):717-38 PMID: 21483598 PMCID: PMC3072116 04/13/2011
  • Imaging retinal mosaics in the living eye. (Rossi EA, Chung M, Dubra A, Hunter JJ, Merigan WH, Williams DR) Eye (Lond) 2011 Mar;25(3):301-8 PMID: 21390064 PMCID: PMC3178316 03/11/2011
  • Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy. (Hunter JJ, Masella B, Dubra A, Sharma R, Yin L, Merigan WH, Palczewska G, Palczewski K, Williams DR) Biomed Opt Express 2010;2(1):139-48 PMID: 21326644 PMCID: PMC3028489 02/18/2011
  • Race- and sex-related differences in retinal thickness and foveal pit morphology. (Wagner-Schuman M, Dubis AM, Nordgren RN, Lei Y, Odell D, Chiao H, Weh E, Fischer W, Sulai Y, Dubra A, Carroll J) Invest Ophthalmol Vis Sci 2011 Jan;52(1):625-34 PMID: 20861480 PMCID: PMC3053303 09/24/2010
  • First-order design of off-axis reflective ophthalmic adaptive optics systems using afocal telescopes. (Gómez-Vieyra A, Dubra A, Malacara-Hernández D, Williams DR) Opt Express 2009 Oct 12;17(21):18906-19 PMID: 20372626 04/08/2010
  • In vivo imaging of microscopic structures in the rat retina. (Geng Y, Greenberg KP, Wolfe R, Gray DC, Hunter JJ, Dubra A, Flannery JG, Williams DR, Porter J) Invest Ophthalmol Vis Sci 2009 Dec;50(12):5872-9 PMID: 19578019 PMCID: PMC2873188 07/07/2009
  • In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic. (Morgan JI, Dubra A, Wolfe R, Merigan WH, Williams DR) Invest Ophthalmol Vis Sci 2009 Mar;50(3):1350-9 PMID: 18952914 PMCID: PMC2790524 10/28/2008
  • Alternating current sensor with second-harmonic detection. (Ferrari JA, Perciante CD, Dubra A, Arnaud A, Frins EM) Appl Opt 2000 Sep 1;39(25):4638-40 PMID: 18350054 03/20/2008
  • Precision synchronous polarimeter with linear response for the measurement of small rotation angles. (Arnaud A, Silveira F, Frins EM, Dubra A, Perciante CD, Ferrari JA) Appl Opt 2000 Jun 1;39(16):2601-4 PMID: 18345177 03/18/2008
  • Current sensor using heterodyne detection. (Ferrari JA, Dubra A, Arnaud A, Perciante D) Appl Opt 1999 May 1;38(13):2808-11 PMID: 18319858 03/06/2008
  • In vivo imaging of the fine structure of rhodamine-labeled macaque retinal ganglion cells. (Gray DC, Wolfe R, Gee BP, Scoles D, Geng Y, Masella BD, Dubra A, Luque S, Williams DR, Merigan WH) Invest Ophthalmol Vis Sci 2008 Jan;49(1):467-73 PMID: 18172127 01/04/2008
  • Robust one-beam interferometer with phase-delay control. (Ferrari JA, Frins EM, Perciante D, Dubra A) Opt Lett 1999 Sep 15;24(18):1272-4 PMID: 18079777 12/15/2007
  • Conversion of bright nondiffracting beams into dark nondiffracting beams by use of the topological properties of polarized light. (Frins EM, Ferrari JA, Dubra A, Perciante D) Opt Lett 2000 Mar 1;25(5):284-6 PMID: 18059855 12/07/2007
  • Wavefront sensor and wavefront corrector matching in adaptive optics. (Dubra A) Opt Express 2007 Mar 19;15(6):2762-9 PMID: 19532513 03/19/2007
  • In vivo fluorescence imaging of primate retinal ganglion cells and retinal pigment epithelial cells. (Gray DC, Merigan W, Wolfing JI, Gee BP, Porter J, Dubra A, Twietmeyer TH, Ahamd K, Tumbar R, Reinholz F, Williams DR) Opt Express 2006 Aug 7;14(16):7144-58 PMID: 19529085 08/07/2006
  • Preisach classical and nonlinear modeling of hysteresis in piezoceramic deformable mirrors. (Dubra A, Massa J, Paterson C) Opt Express 2005 Oct 31;13(22):9062-70 PMID: 19498942 10/31/2005
  • Double lateral shearing interferometer for the quantitative measurement of tear film topography. (Dubra A, Paterson C, Dainty C) Appl Opt 2005 Mar 1;44(7):1191-9 PMID: 15765699 03/16/2005
  • Study of the tear topography dynamics using a lateral shearing interferometer. (Dubra A, Paterson C, Dainty C) Opt Express 2004 Dec 13;12(25):6278-88 PMID: 19488274 12/13/2004
  • Wave-front reconstruction from shear phase maps by use of the discrete Fourier transform. (Dubra A, Paterson C, Dainty C) Appl Opt 2004 Feb 10;43(5):1108-13 PMID: 15008490 03/11/2004
  • Axial irradiance distribution throughout the whole space behind an annular aperture: comments. (Ferrari JA, Dubra A) Appl Opt 2003 Jul 1;42(19):3754-5; discussion 3792-4 PMID: 12868810 07/19/2003
  • Last update: 07/02/2015