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Alfredo Dubra PhD

Alfredo Dubra PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Ophthalmology
Program: Research

Member of the Neuroscience Research Center


Publications

  • Adaptive optics imaging of healthy and abnormal regions of retinal nerve fiber bundles of patients with glaucoma. (Chen MF, Chui TY, Alhadeff P, Rosen RB, Ritch R, Dubra A, Hood DC) Invest Ophthalmol Vis Sci 2015 Jan;56(1):674-81 PMID: 25574048 PMCID: PMC4311778
  • Assessing photoreceptor structure after macular hole closure. (Hansen S, Batson S, Weinlander KM, Cooper RF, Scoles DH, Karth PA, Weinberg DV, Dubra A, Kim JE, Carroll J, Wirostko WJ) Retin Cases Brief Rep 2015;9(1):15-20 PMID: 25525907
  • Assessment of perfused foveal microvascular density and identification of nonperfused capillaries in healthy and vasculopathic eyes. (Pinhas A, Razeen M, Dubow M, Gan A, Chui TY, Shah N, Mehta M, Gentile RC, Weitz R, Walsh JB, Sulai YN, Carroll J, Dubra A, Rosen RB) Invest Ophthalmol Vis Sci 2014 Dec;55(12):8056-66 PMID: 25414179 PMCID: PMC4266074
  • Non-common path aberration correction in an adaptive optics scanning ophthalmoscope. (Sulai YN, Dubra A) Biomed Opt Express 2014 Sep 1;5(9):3059-73 PMID: 25401020 PMCID: PMC4230870
  • Genotype-dependent variability in residual cone structure in achromatopsia: toward developing metrics for assessing cone health. (Dubis AM, Cooper RF, Aboshiha J, Langlo CS, Sundaram V, Liu B, Collison F, Fishman GA, Moore AT, Webster AR, Dubra A, Carroll J, Michaelides M) Invest Ophthalmol Vis Sci 2014 Nov;55(11):7303-11 PMID: 25277229 PMCID: PMC4235328
  • Author response: relationship between foveal cone specialization and pit morphology in albinism. (Wilk MA, Dubra A, Curcio CA, Brilliant MH, Summers CG, Carroll J) Invest Ophthalmol Vis Sci 2014 Sep;55(9):5923 PMID: 25237180
  • A prospective longitudinal study of retinal structure and function in achromatopsia. (Aboshiha J, Dubis AM, Cowing J, Fahy RT, Sundaram V, Bainbridge JW, Ali RR, Dubra A, Nardini M, Webster AR, Moore AT, Rubin G, Carroll J, Michaelides M) Invest Ophthalmol Vis Sci 2014 Sep;55(9):5733-43 PMID: 25103266 PMCID: PMC4161486
  • In vivo imaging of human cone photoreceptor inner segments. (Scoles D, Sulai YN, Langlo CS, Fishman GA, Curcio CA, Carroll J, Dubra A) Invest Ophthalmol Vis Sci 2014 Jul;55(7):4244-51 PMID: 24906859 PMCID: PMC4095721
  • Microscopic inner retinal hyper-reflective phenotypes in retinal and neurologic disease. (Scoles D, Higgins BP, Cooper RF, Dubis AM, Summerfelt P, Weinberg DV, Kim JE, Stepien KE, Carroll J, Dubra A) Invest Ophthalmol Vis Sci 2014 Jul;55(7):4015-29 PMID: 24894394 PMCID: PMC4078949
  • The reliability of parafoveal cone density measurements. (Liu BS, Tarima S, Visotcky A, Pechauer A, Cooper RF, Landsem L, Wilk MA, Godara P, Makhijani V, Sulai YN, Syed N, Yasumura G, Garg AK, Pennesi ME, Lujan BJ, Dubra A, Duncan JL, Carroll J) Br J Ophthalmol 2014 Aug;98(8):1126-31 PMID: 24855115 PMCID: PMC4112420
  • Relationship between foveal cone specialization and pit morphology in albinism. (Wilk MA, McAllister JT, Cooper RF, Dubis AM, Patitucci TN, Summerfelt P, Anderson JL, Stepien KE, Costakos DM, Connor TB Jr, Wirostko WJ, Chiang PW, Dubra A, Curcio CA, Brilliant MH, Summers CG, Carroll J) Invest Ophthalmol Vis Sci 2014 Jul;55(7):4186-98 PMID: 24845642 PMCID: PMC4098060
  • Comparison of adaptive optics scanning light ophthalmoscopic fluorescein angiography and offset pinhole imaging. (Chui TY, Dubow M, Pinhas A, Shah N, Gan A, Weitz R, Sulai YN, Dubra A, Rosen RB) Biomed Opt Express 2014 Apr 1;5(4):1173-89 PMID: 24761299 PMCID: PMC3985984
  • Outer retinal structure after closed-globe blunt ocular trauma. (Flatter JA, Cooper RF, Dubow MJ, Pinhas A, Singh RS, Kapur R, Shah N, Walsh RD, Hong SH, Weinberg DV, Stepien KE, Wirostko WJ, Robison S, Dubra A, Rosen RB, Connor TB Jr, Carroll J) Retina 2014 Oct;34(10):2133-46 PMID: 24752010 PMCID: PMC4175068
  • Visualization of retinal vascular structure and perfusion with a nonconfocal adaptive optics scanning light ophthalmoscope. (Sulai YN, Scoles D, Harvey Z, Dubra A) J Opt Soc Am A Opt Image Sci Vis 2014 Mar 1;31(3):569-79 PMID: 24690655 PMCID: PMC4465430
  • Classification of human retinal microaneurysms using adaptive optics scanning light ophthalmoscope fluorescein angiography. (Dubow M, Pinhas A, Shah N, Cooper RF, Gan A, Gentile RC, Hendrix V, Sulai YN, Carroll J, Chui TY, Walsh JB, Weitz R, Dubra A, Rosen RB) Invest Ophthalmol Vis Sci 2014 Mar;55(3):1299-309 PMID: 24425852 PMCID: PMC3943418
  • In vivo imaging of retinal pigment epithelium cells in age related macular degeneration. (Rossi EA, Rangel-Fonseca P, Parkins K, Fischer W, Latchney LR, Folwell MA, Williams DR, Dubra A, Chung MM) Biomed Opt Express 2013;4(11):2527-39 PMID: 24298413 PMCID: PMC3829547
  • Retinal structure and function in achromatopsia: implications for gene therapy. (Sundaram V, Wilde C, Aboshiha J, Cowing J, Han C, Langlo CS, Chana R, Davidson AE, Sergouniotis PI, Bainbridge JW, Ali RR, Dubra A, Rubin G, Webster AR, Moore AT, Nardini M, Carroll J, Michaelides M) Ophthalmology 2014 Jan;121(1):234-45 PMID: 24148654 PMCID: PMC3895408
  • Human cone visual pigment deletions spare sufficient photoreceptors to warrant gene therapy. (Cideciyan AV, Hufnagel RB, Carroll J, Sumaroka A, Luo X, Schwartz SB, Dubra A, Land M, Michaelides M, Gardner JC, Hardcastle AJ, Moore AT, Sisk RA, Ahmed ZM, Kohl S, Wissinger B, Jacobson SG) Hum Gene Ther 2013 Dec;24(12):993-1006 PMID: 24067079 PMCID: PMC3868405
  • In vivo dark-field imaging of the retinal pigment epithelium cell mosaic. (Scoles D, Sulai YN, Dubra A) Biomed Opt Express 2013;4(9):1710-23 PMID: 24049692 PMCID: PMC3771842
  • In vivo imaging of human retinal microvasculature using adaptive optics scanning light ophthalmoscope fluorescein angiography. (Pinhas A, Dubow M, Shah N, Chui TY, Scoles D, Sulai YN, Weitz R, Walsh JB, Carroll J, Dubra A, Rosen RB) Biomed Opt Express 2013;4(8):1305-17 PMID: 24009994 PMCID: PMC3756583
  • A lensing effect of inner retinal cysts on images of the photoreceptor mosaic. (Langlo CS, Flatter JA, Dubra A, Wirostko WJ, Carroll J) Retina 2014 Feb;34(2):421-2 PMID: 23974999 PMCID: PMC3946899
  • Outer retinal structure in best vitelliform macular dystrophy. (Kay DB, Land ME, Cooper RF, Dubis AM, Godara P, Dubra A, Carroll J, Stepien KE) JAMA Ophthalmol 2013 Sep;131(9):1207-15 PMID: 23765342 PMCID: PMC3968428
  • Automatic cone photoreceptor segmentation using graph theory and dynamic programming. (Chiu SJ, Lokhnygina Y, Dubis AM, Dubra A, Carroll J, Izatt JA, Farsiu S) Biomed Opt Express 2013 Jun 1;4(6):924-37 PMID: 23761854 PMCID: PMC3675871
  • Automatic detection of modal spacing (Yellott's ring) in adaptive optics scanning light ophthalmoscope images. (Cooper RF, Langlo CS, Dubra A, Carroll J) Ophthalmic Physiol Opt 2013 Jul;33(4):540-9 PMID: 23668233 PMCID: PMC3690144
  • Adaptive optics retinal imaging--clinical opportunities and challenges. (Carroll J, Kay DB, Scoles D, Dubra A, Lombardo M) Curr Eye Res 2013 Jul;38(7):709-21 PMID: 23621343 PMCID: PMC4031042
  • Selective cone photoreceptor injury in acute macular neuroretinopathy. (Hansen SO, Cooper RF, Dubra A, Carroll J, Weinberg DV) Retina 2013 Sep;33(8):1650-8 PMID: 23615345 PMCID: PMC4065781
  • First-order design of a reflective viewfinder for adaptive optics ophthalmoscopy. (Dubra A, Sulai YN) Opt Express 2012 Nov 19;20(24):26596-605 PMID: 23187514 PMCID: PMC3601596
  • The effect of cone opsin mutations on retinal structure and the integrity of the photoreceptor mosaic. (Carroll J, Dubra A, Gardner JC, Mizrahi-Meissonnier L, Cooper RF, Dubis AM, Nordgren R, Genead M, Connor TB Jr, Stepien KE, Sharon D, Hunt DM, Banin E, Hardcastle AJ, Moore AT, Williams DR, Fishman G, Neitz J, Neitz M, Michaelides M) Invest Ophthalmol Vis Sci 2012 Dec;53(13):8006-15 PMID: 23139274 PMCID: PMC3816954
  • Assessing retinal structure in complete congenital stationary night blindness and Oguchi disease. (Godara P, Cooper RF, Sergouniotis PI, Diederichs MA, Streb MR, Genead MA, McAnany JJ, Webster AR, Moore AT, Dubis AM, Neitz M, Dubra A, Stone EM, Fishman GA, Han DP, Michaelides M, Carroll J) Am J Ophthalmol 2012 Dec;154(6):987-1001.e1 PMID: 22959359 PMCID: PMC3498541
  • Adaptive optics scanning ophthalmoscopy with annular pupils. (Sulai YN, Dubra A) Biomed Opt Express 2012 Jul 1;3(7):1647-61 PMID: 22808435 PMCID: PMC3395488
  • Adaptive optics retinal imaging in the living mouse eye. (Geng Y, Dubra A, Yin L, Merigan WH, Sharma R, Libby RT, Williams DR) Biomed Opt Express 2012 Apr 1;3(4):715-34 PMID: 22574260 PMCID: PMC3345801
  • Repeatability of in vivo parafoveal cone density and spacing measurements. (Garrioch R, Langlo C, Dubis AM, Cooper RF, Dubra A, Carroll J) Optom Vis Sci 2012 May;89(5):632-43 PMID: 22504330 PMCID: PMC3348369
  • Subclinical photoreceptor disruption in response to severe head trauma. (Stepien KE, Martinez WM, Dubis AM, Cooper RF, Dubra A, Carroll J) Arch Ophthalmol 2012 Mar;130(3):400-2 PMID: 22411676 PMCID: PMC3329123
  • Relationship between the foveal avascular zone and foveal pit morphology. (Dubis AM, Hansen BR, Cooper RF, Beringer J, Dubra A, Carroll J) Invest Ophthalmol Vis Sci 2012 Mar;53(3):1628-36 PMID: 22323466 PMCID: PMC3339921
  • Spatial and temporal variation of rod photoreceptor reflectance in the human retina. (Cooper RF, Dubis AM, Pavaskar A, Rha J, Dubra A, Carroll J) Biomed Opt Express 2011 Sep 1;2(9):2577-89 PMID: 21991550 PMCID: PMC3184867
  • Retinal crystals in type 2 idiopathic macular telangiectasia. (Sallo FB, Leung I, Chung M, Wolf-Schnurrbusch UE, Dubra A, Williams DR, Clemons T, Pauleikhoff D, Bird AC, Peto T, MacTel Study Group) Ophthalmology 2011 Dec;118(12):2461-7 PMID: 21839520 PMCID: PMC3433242
  • Photoreceptor structure and function in patients with congenital achromatopsia. (Genead MA, Fishman GA, Rha J, Dubis AM, Bonci DM, Dubra A, Stone EM, Neitz M, Carroll J) Invest Ophthalmol Vis Sci 2011 Sep;52(10):7298-308 PMID: 21778272 PMCID: PMC3183969
  • Noninvasive imaging of the human rod photoreceptor mosaic using a confocal adaptive optics scanning ophthalmoscope. (Dubra A, Sulai Y, Norris JL, Cooper RF, Dubis AM, Williams DR, Carroll J) Biomed Opt Express 2011 Jul 1;2(7):1864-76 PMID: 21750765 PMCID: PMC3130574
  • Reflective afocal broadband adaptive optics scanning ophthalmoscope. (Dubra A, Sulai Y) Biomed Opt Express 2011 Jun 1;2(6):1757-68 PMID: 21698035 PMCID: PMC3114240
  • Variability in parafoveal cone mosaic in normal trichromatic individuals. (Dees EW, Dubra A, Baraas RC) Biomed Opt Express 2011;2(5):1351-8 PMID: 21559146 PMCID: PMC3087591
  • Optical properties of the mouse eye. (Geng Y, Schery LA, Sharma R, Dubra A, Ahmad K, Libby RT, Williams DR) Biomed Opt Express 2011;2(4):717-38 PMID: 21483598 PMCID: PMC3072116
  • Imaging retinal mosaics in the living eye. (Rossi EA, Chung M, Dubra A, Hunter JJ, Merigan WH, Williams DR) Eye (Lond) 2011 Mar;25(3):301-8 PMID: 21390064 PMCID: PMC3178316
  • Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy. (Hunter JJ, Masella B, Dubra A, Sharma R, Yin L, Merigan WH, Palczewska G, Palczewski K, Williams DR) Biomed Opt Express 2010;2(1):139-48 PMID: 21326644 PMCID: PMC3028489
  • Race- and sex-related differences in retinal thickness and foveal pit morphology. (Wagner-Schuman M, Dubis AM, Nordgren RN, Lei Y, Odell D, Chiao H, Weh E, Fischer W, Sulai Y, Dubra A, Carroll J) Invest Ophthalmol Vis Sci 2011 Jan;52(1):625-34 PMID: 20861480 PMCID: PMC3053303
  • First-order design of off-axis reflective ophthalmic adaptive optics systems using afocal telescopes. (Gómez-Vieyra A, Dubra A, Malacara-Hernández D, Williams DR) Opt Express 2009 Oct 12;17(21):18906-19 PMID: 20372626
  • In vivo imaging of microscopic structures in the rat retina. (Geng Y, Greenberg KP, Wolfe R, Gray DC, Hunter JJ, Dubra A, Flannery JG, Williams DR, Porter J) Invest Ophthalmol Vis Sci 2009 Dec;50(12):5872-9 PMID: 19578019 PMCID: PMC2873188
  • In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic. (Morgan JI, Dubra A, Wolfe R, Merigan WH, Williams DR) Invest Ophthalmol Vis Sci 2009 Mar;50(3):1350-9 PMID: 18952914 PMCID: PMC2790524
  • Alternating current sensor with second-harmonic detection. (Ferrari JA, Perciante CD, Dubra A, Arnaud A, Frins EM) Appl Opt 2000 Sep 1;39(25):4638-40 PMID: 18350054
  • Precision synchronous polarimeter with linear response for the measurement of small rotation angles. (Arnaud A, Silveira F, Frins EM, Dubra A, Perciante CD, Ferrari JA) Appl Opt 2000 Jun 1;39(16):2601-4 PMID: 18345177
  • Current sensor using heterodyne detection. (Ferrari JA, Dubra A, Arnaud A, Perciante D) Appl Opt 1999 May 1;38(13):2808-11 PMID: 18319858
  • In vivo imaging of the fine structure of rhodamine-labeled macaque retinal ganglion cells. (Gray DC, Wolfe R, Gee BP, Scoles D, Geng Y, Masella BD, Dubra A, Luque S, Williams DR, Merigan WH) Invest Ophthalmol Vis Sci 2008 Jan;49(1):467-73 PMID: 18172127
  • Robust one-beam interferometer with phase-delay control. (Ferrari JA, Frins EM, Perciante D, Dubra A) Opt Lett 1999 Sep 15;24(18):1272-4 PMID: 18079777
  • Conversion of bright nondiffracting beams into dark nondiffracting beams by use of the topological properties of polarized light. (Frins EM, Ferrari JA, Dubra A, Perciante D) Opt Lett 2000 Mar 1;25(5):284-6 PMID: 18059855
  • Wavefront sensor and wavefront corrector matching in adaptive optics. (Dubra A) Opt Express 2007 Mar 19;15(6):2762-9 PMID: 19532513
  • In vivo fluorescence imaging of primate retinal ganglion cells and retinal pigment epithelial cells. (Gray DC, Merigan W, Wolfing JI, Gee BP, Porter J, Dubra A, Twietmeyer TH, Ahamd K, Tumbar R, Reinholz F, Williams DR) Opt Express 2006 Aug 7;14(16):7144-58 PMID: 19529085
  • Preisach classical and nonlinear modeling of hysteresis in piezoceramic deformable mirrors. (Dubra A, Massa J, Paterson C) Opt Express 2005 Oct 31;13(22):9062-70 PMID: 19498942
  • Double lateral shearing interferometer for the quantitative measurement of tear film topography. (Dubra A, Paterson C, Dainty C) Appl Opt 2005 Mar 1;44(7):1191-9 PMID: 15765699
  • Study of the tear topography dynamics using a lateral shearing interferometer. (Dubra A, Paterson C, Dainty C) Opt Express 2004 Dec 13;12(25):6278-88 PMID: 19488274
  • Wave-front reconstruction from shear phase maps by use of the discrete Fourier transform. (Dubra A, Paterson C, Dainty C) Appl Opt 2004 Feb 10;43(5):1108-13 PMID: 15008490
  • Axial irradiance distribution throughout the whole space behind an annular aperture: comments. (Ferrari JA, Dubra A) Appl Opt 2003 Jul 1;42(19):3754-5; discussion 3792-4 PMID: 12868810
  • Last update: 07/02/2015